UNICORN 7.0.1 Information Letter

UNICORN™ 7.0.1
Information Letter
1 Introduction
1
Introduction
This Information letter contains descriptions of different scenarios that may occur when
UNICORN 7.0.1 is used. If applicable, actions to avoid or correct problems resulting from
the described scenarios are suggested.
The information is valid for UNICORN 7.0.1 software (build 7.0.1.167).
Operating systems
UNICORN 7.0.1 Client and Instrument Server is verified on the following operating system:
•
Windows® 7 Professional with SP1 installed, 32-bit and 64-bit
SQL Server
The UNICORN database is verified for:
2
•
SQL Server® 2008 R2, 32-bit and 64-bit, running on Windows 7 Professional with
SP1 installed, 32-bit and 64-bit
•
SQL Server 2012 with SP1 installed, 64-bit, running on Windows Server 2012
•
SQL Server 2014, 64-bit, running on Windows Server 2012
UNICORN 7.0.1 Information Letter 29159401 AA
2 General items
2
General items
The following scenarios concern miscellaneous general functions in UNICORN 7.0.1.
OPC
Scenario
Action
Scouting on the Any column and/or ColumnSameAsMain is not supported for OPC.
No further action required.
Ref nbr 33793
The data gets truncated when retrieving very large
quantities of data through OPC Historical Data
Access. For example when retrieving the global
audit trail for a year.
Narrow down the data selection.
Ref nbr 35213
On a Windows 7 64-bit installation the OPC Core
Redistributable is wrongly named as being version
105.0. The correct and installed version number
is 105.1.
It is possible to verify that version 105.1 is installed by checking the Version column for OPC
Core Redistributable in the Programs and Features item in
Control Panel. The correct version is listed as 3.00.10501.
An internal error is displayed when a user that
belongs to a different user group than the previously logged in user tries to log in.
Restart the OPC Historical Data
Access service.
Ref nbr 298995
UNICORN 7.0.1 Information Letter 29159401 AA
3
2 General items
Upgrade
Scenario
Action
When upgrading the database from the installation program only the database on
localhost/UNICORN named UNICORN will be upgraded.
If another UNICORN database is
in use you must perform a
manual database upgrade. Refer to a GE representative for instructions on how to do this.
Note:
This scenario only applies if you are using an external SQL server.
Other
Scenario
Action
Buttons and other interface items are not positioned correctly in the UNICORN dialog boxes.
The size of Windows interface
text must be set 100% in Windows Control Panel.
The system may behave unexpectedly if the client
computer's clock is not in sync with the clock of
the database server.
Ref nbr 23899
4
1
Click the Windows Start
button.
2
Type Display in the Start
menu search field.
3
Click the Display item that
is displayed as the search
result
4
Click 100% to set the size of
text and other items on your
screen.
5
Click Apply.
Ensure that the computer clocks
are synchronized between the
database server and all client
computers in the network.
UNICORN 7.0.1 Information Letter 29159401 AA
2 General items
Scenario
Action
Printing system performance reports from evaluation procedures does not work.
There are two possible solutions:
Ref nbr 29755
•
Ref nbr 29748
Ref nbr 28474
Make sure that the Print to
file check box is selected
when starting a system performance run (this is the default option).
This will save a local copy in
the UNICORN\Temp folder
on the UNICORN instrument
server computer.
•
Make sure that the
UNICORN instrument server
process is run by a Windows
user with administration
properties and defined
printers instead of by the
default local system account.
This will make the system
performance and evaluation
procedure to print as expected.
An anti-virus and malware program detects a
threat from the file opcenum.exe.
Allow the file to run as it is.
Ref nbr 32798
The UNICORN performance is not optimal.
Shut down and restart UNICORN
at regular intervals to ensure
optimal performance.
Files that UNICORN needs to write to are locked
because of a virus scan in the UNICORN folder.
Avoid virus scanning the
UNICORN folder since some
scanning software can lock files
that UNICORN needs to write to.
External software can affect the UNICORN software.
As a first step of troubleshooting, remove or deactivate any
external software installed on
the computer.
UNICORN 7.0.1 Information Letter 29159401 AA
5
2 General items
Scenario
Action
When setting passwords in a dialog box, it is not
possible to set Log on password and Signature
password to the same password.
All users should be informed
about this limitation when
changing passwords.
For example, in the Log on - UNICORN dialog box
when you access a newly installed system for the
first time. If you set the same password for both
Log on password and Signature password, a
warning message is received and you need to
change the passwords before you can continue.
However, it is possible to change passwords in
any UNICORN module and then also to set the
same password for both Log on password and
Signature password. If you set the same password in this manner, you will not receive a warning
and you do not have to change passwords in order to continue.
6
UNICORN 7.0.1 Information Letter 29159401 AA
3 Administration module
3
Administration module
The following scenarios mainly concern functions in the UNICORN 7.0.1 Administration
module.
Scenario
Action
A new e-mail address has been set in E-mail Setup, but alarm notifications are still sent from the
old address.
Restart the instrument server for
the changes in E-mail Setup to
take effect.
Ref nbr 37333
UNICORN 7.0.1 Information Letter 29159401 AA
7
4 Method editor module
4
Method editor module
The following scenarios mainly concern functions in the UNICORN 7.0.1 Method Editor.
Scenario
Action
Error message is shown when saving a user created method phase to the phase library if the
phase contains a column.
No further action required.
Ref nbr 11498
When a method containing invalid instructions is
open, it is not possible to open the Print or Duration & Variables dialog boxes.
No further action required.
Ref nbr 11476
Importing an individual column may cause a
change in the access scope of the associated
column type, for example a predefined or personal
column type is changed to global.
No further action required.
Ref nbr 23172
Importing a method block into a phase will cause
the phase to be shown as text edited. However, if
the imported block also causes consequential
changes in subsequent phases, the affected
phases may not be shown as text edited. Changes
made in the phase properties for these phases
may cause errors.
No further action required.
Ref nbr 23233
When using the option Inject all sample using air
sensor for more than one sample with inlets on
an extra sample inlet valve, sample injected after
the first injection will not be applied to the column.
This is because air may be introduced between
the first and the second sample inlet valves.
If the air sensor sensitivity is set
to High, the sample application
may still proceed. Contact the
GE Healthcare support for information.
Ref nbr 26205
8
UNICORN 7.0.1 Information Letter 29159401 AA
4 Method editor module
Scenario
Action
When importing a method created for ÄKTA™
avant 25 to an ÄKTA avant 150 system, the
method will be saved for the larger system but
the system related parameters will not be adjusted.
A method that is imported from
one system type to be used with
another system must be converted.
Ref nbr 30147
Ref nbr 30307
When importing a method created for ÄKTA pure
25 to an ÄKTA pure 150 system, the method will
be saved for the larger system but the system related parameters will not be adjusted.
If a method is imported and not
converted, the conversion of
method parameters must be
done manually.
A method that is imported from
one system type to be used with
another system must be converted.
The conversion of method parameters must be done manually. The Adapt method function
is not supported between ÄKTA
pure 25 and ÄKTA pure 150 systems, and vice versa. For more
information, refer to ÄKTA pure
User Manual.
Importing a new column list does not work. An
error message is displayed, stating that the file is
corrupt.
The column list must be imported with the Column Type tab
selected. It is not possible when
the Column tab is selected.
Messages during AxiChrom™ packing with Master
are incorrect. They tell you to click Continue after
a specified action but the button is named Confirm and Continue.
Click Confirm and Continue
when the wizard states that you
should click Continue.
The buttons are named differently in
UNICORN 7.0.1 than in UNICORN 5 and since the
wizard has not been changed between the two
versions the information is invalid.
Ref nbr 35815
The column list installed in the UNICORN database
is outdated.
Ref nbr 36473
UNICORN 7.0.1 Information Letter 29159401 AA
Install the column list supplied
on the DVD or download the
latest version of the column list
from the web (updated regularly).
9
4 Method editor module
Scenario
Action
Signatures are not visible in an imported method
created with a system using a different instrument
configuration than the connected system.
The imported method must be
saved before the signatures can
be seen.
Ref nbr 37649
The same instrument configuration as from where the method
was exported must be installed
in the target database prior to
method import.
A user without access to create or edit global
phases saves a personal phase with the same
name as a global phase and overwrites the global
phase.
Avoid creating a personal phase
with the same name as a global
phase.
Ref nbr 34584
Multiple Hold until instructions on the same
breakpoint in a method does not work as expected.
Separate each Hold until instruction by at least the minimum
time resolution, 0.01 hours.
Ref nbr 40869
10
UNICORN 7.0.1 Information Letter 29159401 AA
5 System Control module
5
System Control module
The following scenarios mainly concern functions in the UNICORN 7.0.1 System Control
module.
Scenario
Action
Several methods using the same column are
placed in a system queue. If the column reaches
the notification limit of how many runs that can
be performed before a CIP must be run, the
method runs will still proceed until all methods in
the queue are finished. The system queue will in
effect bypass the set maximum number of runs
before CIP.
Verify that the column can be
used for enough runs before
more method runs are added to
the system queue.
Ref nbr 22042
Column statistics for the current run may be lost
when data is recovered after a temporary connection failure between the instrument server and
the database.
No further action required.
Ref nbr 22264
For ÄKTA avant the process picture in the Process
Picture pane is not updated properly with live information.
•
Ref nbr 22956
Repair the OPC Core Components. In Windows Control
Panel, click Programs and
features, right-click the OPC
Core Components item and
then click Repair
or
•
Selecting to unhide or hide the run log in System
Control may have unexpected effects. For example, the run log may appear behind the process
picture if it is first hidden and the user then selects
to show the run log.
Update the instrument configuration to version 2.0 or
later (ÄKTA avant 150); or
version 3.0 or later (ÄKTA
avant 25).
Restore the default view. On the
View menu, click Restore to Default.
Ref nbr 23449
UNICORN 7.0.1 Information Letter 29159401 AA
11
5 System Control module
Scenario
Action
Copy to clipboard and Copy to metafile do not
show curves when pasted into other applications
and do not open at all in some viewers. This may
be caused by additional data samples arriving at
the copy operation, or by too much data in the
copied chromatogram.
•
Try again.
•
Use an external software
tool to make a screen capture.
•
Wait until the method has
ended and then retry.
•
Wait until the method has
ended and open the created
result file. Perform copy to
clipboard/copy to metafile
from the Evaluation module.
Ref nbr 24932
An instrument module is lost and found during a
scouting run and Preparing for new run is stated
over and over again.
Reboot the computer.
This is due to that re-scan and start of next
method are not synchronized, so a strategy
download during run causes the queue in the CU
to get full and the communication is lost.
Ref nbr 34895
No data update is shown on the screen in System
Control. This can happen when the network cable
between the CU and the PC has been disconnected and the CU memory gets full. The method run
at the time will complete its run, but the scouting
runs and the queued methods that follow will be
cancelled.
Connect the cable and restart
the UNICORN instrument server,
then start the methods or
method queue again.
Ref nbr 34458
For CU-950 and CU-960 based systems, it is not
possible to trigger the system notifications set in
the Maintenance Manager in System Control.
Restart the instrument server to
activate the system notifications.
Ref nbr 35394
Parameter values for the quaternary valve are
changed in the start protocol, but the run log includes the original parameter values.
Ref nbr 33608
12
Do not change the parameter
values for the quaternary valve
in the start protocol. Update the
method instead.
UNICORN 7.0.1 Information Letter 29159401 AA
5 System Control module
Scenario
Action
The System Control panes are minimized and
fixed in the upper left corner.
1
Disconnect from the system.
2
In System Control, hide or
unhide the Method Navigator pane.
3
Connect to the system
1
Restore the default view. On
the View menu, click Restore to Default.
2
Disconnect and reconnect
the system.
1
Restore the default view. On
the View menu, click Restore to Default.
2
Disconnect and reconnect
the system.
Ref nbr 35568
The System Control panes do not open after reconnecting to an instrument that has been in
power save mode.
Ref nbr 37743
It is not possible to perform manual instructions
after reconnecting to an instrument that has been
in power save mode and a method run has been
started.
Ref nbr 37743
The instrument connection progress bar is neverending and cannot be canceled.
Disconnect and reconnect the
system.
Ref nbr 35594
Variable values are pasted into the Start Protocol,
but when the method starts, the old variable values are used.
Type in the variables, do not
copy and paste.
Ref nbr 38004
The Windows user has been logged out, or the
computer has been shut down during a manual
or a method run. When the computer has
restarted and the user has logged on to Windows,
the controls in System Control are grayed out
during the data upload from CU-950 or CU-960.
Let the data completely upload
from the CU-950 or CU-960. A
progress bar is shown during
the upload.
Note:
Data upload is only possible if it is an Ethernet
connection between the computer and the CU, and
if the CU has a flash memory installed.
UNICORN 7.0.1 Information Letter 29159401 AA
13
5 System Control module
Scenario
Action
Not possible to reconnect to the system, in a network installation, if the instrument controlling
computer or in the case of cell cultivation, the
rocker, loses network connection for a longer period of time.
Set up the network to use a fixed
IP-address for the rocker.
The rocker has been given a new IP-address when
reconnecting to the network.
Ref nbr 40657
For ÄKTA avant systems: there is indications in the
Run Log and the Audit Trail, that user OPC is
connected in view mode.
No further action required.
Since the Process Picture for ÄKTA avant uses
OPC for receiving information from the system
this does not indicate an error in the system.
14
UNICORN 7.0.1 Information Letter 29159401 AA
6 Evaluation Classic module
6
Evaluation Classic module
The following scenarios mainly concern functions in the UNICORN 7.0.1 Evaluation
Classic module.
Scenario
Action
The RUN_PROGRAM instruction does not open
and display an image editing application as expected when it is used in an evaluation procedure
at the end of a method run.
The instrument service has no
access to the desktop of the
logged in users so the user interface of the application started
by the RUN_PROGRAM instruction will not be displayed, even
if it is started by the instruction.
Ref nbr 14071
When copying a curve to a chromatogram where
the properties of the x-axis have been adjusted
to 0 at injection, the copied curve will not align
correctly since the injection mark for the copied
curve is not included.
Ref nbr 23914
When importing UNICORN 5 results larger than
10 MB, an files could not be imported error is
displayed.
Ref nbr 36448
When trying to export a result that contains
curves, the menu item Curves on the To Unicorn
menu and the Externally menu (under the File
and Export menus) are unavailable even though
it should be possible to click Curves.
Instead of copying, use the
Open Curve function to open a
copy of the curve including the
injection mark curve.
Note that the result containing
the curve must be saved before
the curve can be opened.
Split the result into smaller results and import the subset results. Then merge them in
UNICORN 7.0.1.
Close and reopen the result.
Ref nbr 37631
Some instructions in the Evaluation Procedure
Editor are not correctly implemented and will not
produce any output.
No further action required.
This applies to some of the export formats and
some chromatogram operations.
UNICORN 7.0.1 Information Letter 29159401 AA
15
7 Evaluation module
7
Evaluation module
The following scenarios mainly concern functions in the UNICORN 7.0.1 Evaluation
module.
Scenario
Action
When importing UNICORN 5 results larger than
10 MB, an files could not be imported error is
displayed.
Split the result into smaller results and import the subset results. Then merge them in
UNICORN 7.0.1.
Ref nbr 36448
When importing UNICORN 5.x results where Any
column has been used, the column volume will
not be stored correctly. As a result the function
Compare in CV does not work.
16
No further action required.
UNICORN 7.0.1 Information Letter 29159401 AA
For local office contact information, visit
www.gelifesciences.com/contact
GE and GE monogram are trademarks of General Electric Company.
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Björkgatan 30
751 84 Uppsala
Sweden
Windows, Microsoft and SQL Server are registered trademarks of Microsoft
Corporation.
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www.gelifesciences.com/unicorn
ÄKTA, AxiChrom and UNICORN are trademarks of General Electric Company or
one of its subsidiaries.
All other third party trademarks are the property of their respective owner.
Any use of UNICORN is subject to GE Healthcare Standard Software End-User
License Agreement for Life Sciences Software Products. A copy of this Standard
Software End-User License Agreement is available on request.
UNICORN 7 © 2009 - 2015 General Electric Company
© 2009 - 2015 General Electric Company – All rights reserved.
First published Oct. 2015
All goods and services are sold subject to the terms and conditions of sale of
the company within GE Healthcare which supplies them. A copy of these terms
and conditions is available on request. Contact your local GE Healthcare representative for the most current information.
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29159401 AA 10/2015 a201