Denmark, Finland, Iceland, Norway, Sweden

Denmark, Finland, Iceland, Norway, Sweden
Thermo Scientific Training Courses
The key to your laboratory’s success
2
016 Training Programme Denmark, Finland,
Iceland, Norway, Sweden
Invest in Yourself
People are the most valuable assets in any lab. We offer comprehensive, professional training
and certification through a complete course portfolio that can help you achieve the most from
your instrumentation and results.
Our ultimate goal is to provide you with a total solution for your analytical needs, and so
we offer a wide range of training courses on:
• Instrument operation - hardware and software
• Instrument maintenance
• Software and applications
Optimal classroom settings and world-class instructors will enhance your learning
experience and allow you to gain greater productivity. As experts in their disciplines,
our experienced specialists can provide a variety of education solutions to ensure
that students are able to get the most value from their investment and achieve
relative practical and theoretical knowledge. A range of venues are available for your
convenience: on-site or at one of our Centers of Excellence.
We look forward to discussing your training needs and working with you to ensure
your success with our products.
Table of Contents
Life Sciences Mass Spectrometry (LSMS)
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Proteomics 5
Small Molecules
3
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Training Schedule 2016
17
Chromatography
18
GC
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GC-MS
21
Chromeleon Software 26
Ion Chromatography 28
HPLC Systems 29
On-Site Training Courses 31
Training Schedule 2016 32
Trace Elemental Analysis
33
Atomic Absorption Spectroscopy (AAS)
34
Inductively Coupled Plasma Spectroscopy (ICP-OES)
35
Training Schedule 2016
36
Inorganic Mass Spectrometry
37
ICP-MS
38
Training Schedule 2016 39
Advance your Knowledge
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How to Register
41
Life Sciences Mass Spectrometry
Invest in Yourself. Whether you would like to enhance your learning experience or gain
greater productivity, the Life Sciences Mass Spectrometry courses are designed to ensure
each student has time to address their specific topics of interest. The courses offer both
practical and theoretical training and are taught by experienced and certified instructors.
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Life Sciences Mass Spectrometry
Proteomics
Training: Ion Trap and LTQ Orbitrap Biotech Operations
Course Objective:
This course is designed for users that have previous LC-MS experience and are interested in protein and peptide analysis. It is specific to the
Thermo Scientific™ LTQ Orbitrap™ and ion trap mass spectrometers and will include instruction for electrospray ionization (ESI) of proteins and
peptides, instruction for setting up dynamic and static nanospray (NSI), calibration and basic maintenance, setup and optimization of various
data-dependent acquisition methods. In addition, there will be an in depth discussion of qualitative analysis and processing of accurate mass
methods with Thermo Scientific™ Xcalibur™, Proteome Discoverer™ and SIEVE™ software programs. When ETD training is requested, the
following topics can be incorporated to the course timetable: maintenance of ETD source, optimization, tuning and calibration of the ETD
components, experimental set-up, ETD data processing.
The course material includes:
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•
•
•
•
Ion Trap and Orbitrap Theory
Tuning and Calibration
Hands-on ESI and NSI MS
Data Dependent Method Design
Post-Translational Modification Methods
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•
Parallel Detection Methods
Accurate Mass Methods
Xcalibur Software for Qualitative Methods
Proteome Discoverer Software
Basic Thermo Scientific LTQ Maintenance
This course is offered at customer site only
Training: Q Exactive Biotech Operations
Course Objective:
This course is designed for users that have previous LC-MS experience and are interested in protein and peptide analysis. It is specific to
the Thermo Scientific™ Q Exactive™ mass spectrometer and will include instruction for electrospray ionization (ESI) of proteins and peptides,
instruction for setting up dynamic and static nanospray (NSI), calibration and basic maintenance, setup and optimization of the various data
dependent acquisition methods. In addition, there will be an in depth discussion of qualitative analysis and processing of accurate mass
methods with Thermo Scientific Xcalibur, Proteome Discoverer, FT and SIEVE software programs. Information on the Thermo Scientific™
Pinpoint software can be also be included in the training course.
The course material includes:
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•
•
•
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Quadrupole and Orbitrap Theory
Quadrupole and Orbitrap Hardware Instrument Tuning and Calibration
Nano-flow LC Method Development
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Data Dependent and Multiplexing Method Design
Xcalibur Set Up and Processing
Proteome Discoverer Software
Processing of Post Translation Modification Methods
Life Sciences Mass Spectrometry
Proteomics
Training: TSQ Biotech Operations
Course Objective:
The aim of this training course is to familiarize the new Thermo Scientific™ TSQ™ mass spectrometer user with instrument operation for the
purposes of protein and peptide quantitation. It includes instruction for electrospray (ESI) and nanospray (NSI) ionization of proteins and peptides,
instrument calibration and tuning, data collection, maintenance and functionality of Thermo Scientific Xcalibur and Pinpoint software packages.
The training content can be customized according to the customer’s specific needs.
The course material includes:
• TSQ Hardware and Theory
• Tuning and Calibration
• Hands-on ESI and NSI MS
•Maintenance
• Parameters necessary for Good Quantitation
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•
•
•
•
Xcalibur Software for Quantitative Methods
Pinpoint Software
Instrument Method Development
Data Processing
Introduction to Skyline
This course is offered at customer site only
Training: Fusion Biotech Operations
Course Objective:
This course is designed for users who have previous LC-MS experience and are interested in protein and peptide analysis. It is specific to the
Thermo Scientific™ Orbitrap Fusion™ and Fusion Lumos Tribrid Mass Spectrometers and will include instruction for electrospray ionization
(ESI) of proteins and peptides, instruction for setting up dynamic and static nanospray (NSI), calibration and basic maintenance, and setup
and optimization of various data-dependent acquisition methods. In addition, there will be an in depth discussion of qualitative analysis and
processing of accurate mass methods with Thermo Scientific Xcalibur, Proteome Discoverer, and SIEVE software programs. When ETD training is
requested, the following topics can be incorporated to the course timetable: maintenance of ETD source, optimization, tuning and calibration of
the ETD components, experimental set-up, ETD data processing.
The course material includes:
• Dual Pressure Linear Ion Trap, Quadrupole and Orbitrap Theory
• Basic Tune and Calibration
• Hands-on ESI and NSI MS
• Data Dependent Method Design
• Post-Translational Modification Methods
• Parallel Detection Methods
• Accurate Mass Methods
This course is offered at customer site only
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• Proteome Discoverer Software
• Basic Maintenance
Life Sciences Mass Spectrometry
Proteomics
Training: Proteome Discoverer Software
Course Objective:
The aim of this training course is to provide new users with the ability to use the Thermo Scientific Proteome Discoverer software to its full
potential. Proteome Discoverer is a flexible, expandable software platform for the analysis of qualitative and quantitative proteomics data.
Detailed presentations will be given on all modules together with hands on exercises in order to ensure understanding of all the processes.
The students will become familiar with database manipulation, database search parameters as well as the interpretation of results. By the
end of the course they should be able to apply all software tools for their own purposes.
Training: SIEVE Software
Course Objective:
Thermo Scientific SIEVE software provides label-free quantitative differential expression analysis of proteins and peptides from the comparison
of multiple LC/MS datasets. It is a statistically rigorous tool for analyzing data from biomarker discovery experiments. This course will allow
the new user to use all modules of the software successfully. The students will become familiar with chromatographic alignment, statistical
evaluation and database searching. By the end of the course they should be able to apply all software tools for their own purposes.
Training: PepFinder Software
Course Objective:
For biotherapeutic proteins to be effective, they must be produced in biologically active forms with proper folding and post-translation
modifications (PTMs).
Thermo Scientific™ PepFinder software makes it easy to define the target protein sequence, select a proteolytic digest enzyme, and assign known
and potential post-translational modifications to search. Protein sequences can be imported from FASTA and text files, or sequences can be
pasted into a text box.
The aim of this training course is to provide new users with the ability to use PepFinder software to its full potential.The user will be able to
create automated workflows necessary for an in-depth characterization of biotherapeutic proteins (glycopeptides identification, disulfide bond
mapping, quantification of PTM’s including oxidation, deamidation, phosphorylation). The users will also learn how to perform error tolerant and
amino acid searches as well as processing Peptide Mapping raw data.
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Life Sciences Mass Spectrometry
Proteomics
Training: Pinpoint software
Course Objective:
The aim of this training course is to provide new users with the ability to use the Pinpoint software to its full potential in combination with
TSQ, LTQ Orbitrap or Q Exactive data. Pinpoint software assists in the fast development of quantitative protein/peptide assays and provides
a great tool for processing data from quantitative analyses. The course will cover all aspects of the identification, characterisation and
quantification of biological samples, providing a complete start-to-finish workflow for biomarker ID and verification. MSn and High-Resolution/
Accurate Mass (HR/AM) data as well as Selected Reaction Monitoring (SRM and iSRM) transitions data can be processed. The training
content can be customized for the customer’s needs and this module can also be combined with the TSQ, LTQ orbitrap and Q Exactive Biotech
Operations courses on offer.
Training: ProSightPC Software
Course Objective:
The aim of this training course is to provide new users with the ability to use Thermo Scientific™ ProSightPC software to its full potential.
ProSightPC is an all round tool for identification and characterization of both intact proteins and peptides. It enables high-throughput processing
of all accurate-mass MS/MS data, whether from top-down, middle-down or bottom-up experiments including the characterization of proteins
with known PTMs. Detailed presentations will be given on all the options available with hands on exercises in order to ensure understanding
of all the processes. The course will cover all the steps from software setup to data reporting, including the use of the multiple search modes
available to determine the exact protein sequence including modifications and alternative splicing.
Training: Protein Deconvolution Software
Course Objective:
The aim of this training course is to provide new users with the ability to use Thermo Scientific™ Protein Deconvolution software to its full
potential. Protein Deconvolution significantly improves the identification and characterization of intact proteins from mass spectrometric data.
It is the only protein deconvolution software available today that takes full advantage of the ultra-high-resolution, accurate-mass data produced
by Orbitrap-based mass spectrometers. Detailed presentations will be given on all the options available with hands on exercises in order to
ensure understanding of all the processes. The course will cover all the steps necessary to the use of the two built-in algorithms (Xtract and
ReSpect), deconvoluted data handling and reporting. Guidelines on intact protein analysis for Thermo Scientific mass spectrometers will also
be provided.
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Life Sciences Mass Spectrometry
Small Molecules
Training: Fusion Operations
Course Objective:
The Fusion Operations course is designed for users that have previous LC-MS experience and would like to familiarize themselves with the
Orbitrap Fusion mass spectrometer. The course will cover API and ion trap theory, tuning, calibration, data collection, general functionality
of the Xcalibur software and main workflows for additional processing softwares. The emphasis of the training is on small molecule analysis,
accurate mass applications and data processing.
The course material includes:
• Dual Pressure Linear Ion Trap, Quadrupole and Orbitrap Theory
• Basic Tune and Calibration
• Compound Tuning for MS and MS/MS Purposes
• Data Dependent Method Design
• Introduction to Qual Browser/Freestyle
• Accurate Mass Methods
• Parallel Detection Methods
• Introduction to Elemental Composition and Structure Elucidation
Training: Ion Trap Operations
Course Objective:
The aim of this training course is to familiarize the new ion trap user with basic instrument operation, including API and ion trap theory (linear
and 3D, single and dual traps), tuning, calibration, data collection, maintenance, and general functionality of the Xcalibur software package.
The focus of this course is small molecule analysis for both qualitative and quantitative purposes. No attempt is made to teach protein mapping
or peptide sequencing. Students desiring focused instruction on peptide/protein analysis should explore the possibility of taking one of the
Biotech courses on offer, in lieu of this course.
The course material includes:
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•
•
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Ion Trap Theory
Tuning and Calibration
Hands-on APCI and ESI MS
Instrument Method Development for LC/MS
This course is offered at customer site only
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Multi-Stage MS Method Building
Quantitative Analysis
Xcalibur Software
Basic Maintenance
Life Sciences Mass Spectrometry
Small Molecules
Training: LTQ Orbitrap Operations
Course Objective:
The LTQ Orbitrap Operations course is designed for users that have previous LC-MS experience and would like to familiarize themselves with
the LTQ Orbitrap mass spectrometer. The course will cover API and ion trap theory, tuning, calibration, data collection and general functionality of
the Xcalibur software. The emphasis of the training is on small molecule analysis, accurate mass applications and data processing.
The course material includes:
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•
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LTQ 2D Ion Trap and Orbitrap Theory (Single and Dual Traps)
Basic Tune and Calibration
Compound Tuning for MS and MS/MS Purposes
Instrument Method Development for LC/FTMS
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Introduction to Qual Browser
Accurate Mass Methods
Data Dependent Analysis
Quantitation using Xcalibur
This course is offered at customer site only
Training: Metabolite Identification
Course Objective:
The aim of this training course is to familiarize new Thermo Scientific mass spectrometer users with optimal instrument operation and software
options for performing efficient identification of metabolites. The course will cover API and MS theory, tuning, calibration, data collection and
general functionality of the Xcalibur software. In addition, data processing for the purposes of metabolite identification will be performed
using Thermo Scientific software packages.
The course material includes:
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•
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MS Theory
Basic Tune and Calibration
Compound Tuning for MS and MS/MS purposes
Method Development
Data Dependent Analysis and Accurate Mass Methods
This course is offered at customer site only
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Introduction to Qual Browser/Freestyle
Identification of Metabolites using Metworks
Structure Elucidation using Mass Frontier
Cross-Species Comparison using Mass Frontier
Life Sciences Mass Spectrometry
Small Molecules
Training: Structure Elucidation of Unknowns
Course Objective:
The aim of this training course is to familiarize new Thermo Scientific MS users with optimal instrument operation and software options for
performing efficient structure elucidation of unknown small molecules such as: impurities in synthetic samples, toxic compounds, explosives,
environmental components, etc. The course will cover API and MS theory, tuning, calibration, data collection and general functionality of the
Xcalibur software. In addition, Mass Frontier will be used for automatic chromatographic processing, library building and searches of
unknowns, as well as spectra interpretation.
The course material includes:
•
•
•
•
•
Ion Trap and Orbitrap Theory
Basic Tune and Calibration
Compound Tuning for MS and MS/MS Purposes
Method Development
Data Dependent Analysis and Accurate Mass Methods
This course is offered at customer site only
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•
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Introduction to Qual Browser/Freestyle
Component Detection using Mass Frontier
Creation and Interrogation of Libraries in Mass Frontier
Spectra Interpretation using Mass Frontier
Life Sciences Mass Spectrometry
Small Molecules
Training: SIEVE Software
Course Objective:
Thermo Scientific SIEVE software provides a label-free quantitative analysis of metabolic pools by comparison of multiple LC-MS datasets.
It can be used to compare the metabolomes of control versus treated samples as well as from time-course experiments. This course will
enable the new user to utilize all the modules of this software package in order to perform statistically valid metabolome experiments.
The course topics include a familiarization with chromatographic alignments, statistical evaluation of metabolic pool sizes and exact mass
database queries. By the end of the course the student will be able to apply all software tools to fulfill their experimental requirements.
Training: Compound Discoverer Software
Course Objective:
The aim of this training course is to provide new users with the ability to use the Thermo Scientific™ Compound Discoverer™ software to its
full potential.
Compound Discoverer software ensures confident compound identification and structural elucidation in applications as diverse as pharmaceutical
metabolism, impurity analysis, forensic toxicology, and environmental research. The software helps researchers plan how data will be collected,
organized, stored and reported with the final result in mind. Its node-assembled processing workflows, advanced algorithms, and study-oriented
data storage allow users to quickly process and assemble data collected from multiple samples into a unified report.
The training course will cover all the aspects of the software including:
• Isotope pattern trace
• Fragment ion search trace
• Multiple mass defect filtering
•Expected compound search including dealkylation and
dearylation predictions and transformation products
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•Untargeted compound detection with isotope and
adduct grouping
• Fragment ion search (FISh) and structure annotations
• Compare with control experiments
•Reporting
Life Sciences Mass Spectrometry
Small Molecules
Training: TSQ Operations
Course Objective:
The aim of this training course is to familiarize the new TSQ user with instrument operation including atmospheric pressure ionization,
quadrupole principles, compound tuning, instrument calibration, data collection, maintenance and general functionality of Xcalibur and
Thermo Scientific™ TraceFinder™ software packages. The focus of this training course is small molecule quantitation and the different
approaches enabled by hardware and software in this field will be explored. Customers interested in the quantitation of peptides
and proteins should choose the TSQ Biotech Operations course instead.
The course material includes:
• TSQ Hardware Components
• TSQ Scan Modes
• TSQ Instrument Control
• Quantitation using TraceFinder
•XReport
• User Maintenance
Training: Exactive Operations
Course Objective:
The aim of this training course is to familiarize the new Thermo Scientific™ Exactive™ mass spectrometer user with the Orbitrap technology.
This will cover API and Orbitrap theory, tuning, calibration, data collection and general functionality of the Thermo Scientific Xcalibur and
ToxID software packages. The emphasis of the training is on small molecule analysis, accurate mass applications and data processing.
The course material includes:
• Overview of Theory and Practical Operation of the
Thermo Scientific Orbitrap Mass Analyzer
• System Tuning and Calibration Procedures
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• Preventative Maintenance and Troubleshooting Procedures
• Method and Sequence Setup
• Data Processing.
Life Sciences Mass Spectrometry
Small Molecules
Training: Q Exactive Operations
Course Objective:
The aim of this training course is to familiarise the new Q Exactive user with Orbitrap technology. The training agenda covers API, Quadrupole
and Orbitrap theory, tuning, calibration, data collection and general functionality of the Thermo Scientific Xcalibur, LCQuan and Tox ID software
packages. The emphasis of the training course is on small molecule analysis both from a qualitative and quantitative point of view, on accurate
mass applications and data processing.
The course material includes:
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•
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API, Quadrupole and Orbitrap Theory
Q Exactive Hardware Components
Tuning and Calibration
Quantitative Set Up and Processing
• Qualitative Set Up and Processing
• Non Targeted/Unknown Screening
• Troubleshooting and Maintenance
Training: Transcend II Operations
Course Objective:
The aim of this training course is to familiarize the new user with Thermo Scientific™ TurboFlow™ technology that can be used in conjunction with
Thermo Scientific mass spectrometers and allows elimination of sample preparation techniques. The training will cover the theory of turbulent
flow chromatography, hardware setup and maintenance, method development and data acquisition. The students will be guided through all
principles of operation and hands on examples will be used for successful method development.
The course material includes:
• Theory of Turbulent Flow Chromatography
• Hardware Set Up: Autosampler, Injector Ports, Loading and
Eluting Pumps, Multiple Column Module (MCM)
• Acquisition and processing Software: Method Creation, Batch
Set Up, Pressure Trace Read Backs
This course is offered at customer site only
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• Quick Elute Methods
• Focus Mode Method Set Up
- Turbo Flow Column Selection
- Elution Optimization from Analytical Columns
- Method Variables
Life Sciences Mass Spectrometry
Small Molecules
Training: EQuan
Course Objective:
The aim of this course is to familiarize the new user with the Thermo Scientific™ EQuan large volume injection technique. The training will
cover the principles of operation and the theory of the method, hardware setup and maintenance, method setup and data acquisition. All
considerations with respect to large volume injections will be discussed. This training module can be combined with any of the instrument
Operations courses on offer.
Training: TraceFinder Software
Course Objective:
Thermo Scientific™ TraceFinder™ is a software package with built-in workflows that have been developed to assist in routine analysis of
environmental and food residue applications. The aim of this training course is to provide new users with the ability to use the software
to its full potential. Detailed presentations will be given on all TraceFinder functionalities together with hands on exercises in order to ensure
understanding of all the processes. The software setup, user selection and all the steps necessary for data collection and processing, data
analysis and report generation will be covered. This training module can be combined with any of the instrument Operations courses on offer.
Training: LipidSearch
Course Objective:
Thermo Scientific LipidSearch software provides automatic identification and relative quantification of cellular lipid molecular species from large
amounts of mass spectrometric data obtained in nano-infusion or LC-MS experiments. During the course you will learn how to use the software
for different analysis conditions. The student will use practical examples to explore the lipid database, the ID module and how to perform
relative quantitation. The various output options will be discussed. By the end of the student will be able to use LipidSearch to successfully
analyse their lipidomics data.
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Life Sciences Mass Spectrometry
Small Molecules
Training: MSQ Plus Operations
Course Objective:
The aim of this training course is to familiarize the new Thermo Scientific™ MSQ™ mass spectrometer Plus user with instrument operation
including atmospheric pressure ionization, quadrupole principles, compound tuning, instrument calibration, data collection, maintenance
and general functionality of the Thermo Scientific™ Dionex™ Chromeleon™ software package. The focus of this course is small molecule
analysis for both qualitative and quantitative purposes.
The course material includes:
• MSQ Hardware Components
• Maintenance
• Tuning and Mass Calibration
• Compound Optimization and Method Development
• Quantitative SIM Analysis by Electrospray
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• Quantitation using Chromeleon
• Quantitation by APCI
• Cone Fragmentation
• Qualitative Processing
Training Schedule 2016
We currently don’t offer any LSMS courses in our facilities in Denmark, Finland, and Sweden. However all the courses described
in the brochure can be offered at customer sites. LSMS courses are offered at the following facilities:
• Hemel Hempstead, UK
• Villebon sur Yvette, France
• Dreieich, Germany
• Reinach, Switzerland.
For information on training dates and tuition language, please refer to the corresponding brochure.
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Chromatography
Real-World Knowledge. For experienced and new users to our extensive line of
Chromatography instruments, we offer both practical and theoretical training courses
taught by experienced and certified instructors. Course sizes are kept to a minimum
to ensure each student has access to instruments, as well as time to address their
specific topics of interest.
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Chromatography
GC
Training: GC Operations
Course Objective:
The aim of this course is to familiarize the new Thermo Scientific GC user with basic instrument operation including gas chromatography
theory and optimization, routine maintenance, data acquisition and data processing.
The course material includes:
• GC Theory & Optimization
• GC Routine Maintenance
• GC Method and Sequence Set up
• Calibration strategies
• Evaluation of Quantitative Data
•Reporting
Training: Headspace Gas Chromatography
– Technique and TriPlus 300 HS Familiarization
Course Objective:
The course is intended for those new to the technique of Headspace Gas Chromatography and seeks to demonstrate how to build and
optimize methods to maximize both sensitivity and precision. The course explores various headspace techniques such as partition, total
vaporization and Multiple Headspace Extraction (MHE) and explains which technique is most appropriate for various analytical challenges.
This training course is an intensive mixture of theory and practical with instrument operation and maintenance high on the agenda.
The course material includes:
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•
•
•
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Basic Headspace GC Theory
Method Development
Influence of HS variables
HS-GC techniques
• Instrument Calibration
• Liner and column selection
• Instrument maintenance
•Troubleshooting
Chromatography
GC
Training: Triplus Robotic Sampler Handler Familiarization
– Gas Chromatography
Course Objective:
This operations training course is intended for new users of the Thermo Scientific™ Triplus RSHTM Autosampler. The aim of the course is to
deliver a better understanding of automated liquid injection, headspace sampling and solid phase micro extraction using the Triplus RSH.
This training course is an intensive mixture of theory and practical with instrument operation and maintenance high on the agenda.
The course material includes:
•
•
•
•
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Brief Introduction to liquid injection, Headspace and SPME
Introduction to the Triplus RSH and components options
Teaching and checking your objects
Configuring your Triplus RSH for Liquids, Headspace and SPME
• Method Development (liquids, Headspace and SPME)
• Instrument maintenance
• Prep cycles
•Troubleshooting
Chromatography
GC-MS
Training: ISQ Operations
Course Objective:
The aim of this training course is to familiarize the new Thermo Scientific™ ISQ™ GC-MS system user with basic instrument operation
including gas chromatography, optimization for mass spectrometry, maintenance, EI, CI and quadrupole theory, tuning, calibration, data
acquisition, data processing and the general functionality of the Thermo Scientific Xcalibur software package.
The course material includes:
•
•
•
•
GC Theory and Optimisation (EI and CI)
Quadrupole Theory
GC and ISQ Hardware and Maintenance
Scan Functions
• Qualitative Set Up and Processing
• Quantitative Set Up and Processing
• Introduction to new software packages for GC-MS
Training: TSQ 8000 Evo Operations
Course Objective:
The aim of this training course is to familiarize new users of the Thermo Scientific™ TSQ™ 8000 Evo system with basic instrument
operation including gas chromatography optimization for mass spectrometry, maintenance, EI, CI and quadrupole theory, tuning,
calibration, data acquisition, automated SRM development, data processing and the general functionality of the Thermo Scientific
TraceFinder software package.
The course material includes:
• GC Theory and Optimization (EI and CI)
• Quadrupole Theory
• GC and TSQ 8000 Hardware and Maintenance
• Scan Functions
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• Qualitative Set Up and Processing with Xcalibur and Tracefinder
• Quantitative Set Up and Processing with Xcalibur and Tracefinder
Chromatography
GC-MS
Training: Q Exactive GC-MS/MS Operations
Course Objective:
The aim of this training course is to familiarize new users of the Thermo Scientific™ Q Exactive™ GC Orbitrap™ GC-MS/MS system with basic
instrument operation including gas chromatography optimization for mass spectrometry, maintenance, EI, CI, MS/MS and Orbitrap theory,
tuning, calibration, data acquisition, data processing and the general functionality of the TraceFinder software package.
The course material includes:
• GC Theory and MS Source Optimization (EI and CI)
• High resolution and accurate mass: definitions
• Orbitrap Theory
• GC and Q Exactive Hardware and Maintenance
• Scan Functions
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• Qualitative Set Up and Processing TraceFinder
– Target screening with a database
– Deconvolution and High Resolution screening
• Quantitative Set Up and Processing TraceFinder
Chromatography
GC-MS
Training: ISQ Operations
Course Objective:
The aim of this training course is to familiarize the new Thermo Scientific™ ISQ™ GC-MS system user with basic instrument operation
including gas chromatography, optimization for mass spectrometry, maintenance, EI, CI and quadrupole theory, tuning, calibration,
data acquisition, data processing and the general functionality of the Thermo Scientific Chromeleon and TraceFinder software packages.
The course material includes:
• GC Theory and Optimisation (EI and CI)
• Quadrupole Theory
• GC and ISQ (LD and QD) Hardware and Maintenance
• Scan Functions
• Qualitative Set Up and Processing
• Quantitative Set Up and Processing
• Introduction to new software packages for GC-MS
Training: TSQ 8000 Evo Operations
Course Objective:
The aim of this training course is to familiarize new users of the Thermo Scientific™ TSQ™ 8000 Evo system with basic instrument operation
including gas chromatography optimization for mass spectrometry, maintenance, EI, CI and quadrupole theory, tuning, calibration, data
acquisition, automated SRM development, data processing and the general functionality of the Thermo Scientific TraceFinder software
package.
The course material includes:
• GC Theory and Optimization (EI and CI)
• Quadrupole Theory
• GC and TSQ 8000 Hardware and Maintenance
• Scan Functions
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• Qualitative Set Up and Processing with Xcalibur and Tracefinder
• Quantitative Set Up and Processing with Xcalibur and Tracefinder
Chromatography
GC-MS
DFS Instrument Operator Training for Quantitative Applications
Course Objective:
The general objective of the Thermo Scientific™ DFS™ instrument operator training for quantitative applications is to introduce the new
user to quantitative GC/HRMS techniques using dioxin/furan analysis as an example. The course will familiarize users with the operational
techniques and data evaluation procedures needed for high resolution GC/MS MID methods for isotope dilution techniques, following EPA
method 1613 for the analysis of Dioxins/Furans. Please note that for this course, knowledge of the EPA method 1613 or equivalent methods
is required, as well as proficient understanding of mass spectrometry (MS). The participants should have experience in the field
of chromatographic analysis, especially in gas chromatography.
The course material includes:
•Introduction into the Hardware and Basics
of the DFS and General HRM
• Instrument Setup for Dioxin Analysis
• MID (Multiple Ion Detection)
• Data Evaluation using Qual Browser
• Processing Data Using Target Quan
• Generating reports using the Reporter Application
DFS Dual Data Operator Training
Course Objective:
The general objective of the DFS Dual Data Operator training course is to introduce Dual Data acquisition for high throughput applications.
For this course, a proficient understanding of mass spectrometry and DFS operation is expected. The participants should have the Dual Data
option on the DFS system.
The course material includes:
•Introduction into the Hardware and Basics
of the Dual Data Acquisition
• Instrument setup for Dual Data Analysis
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•Troubleshooting and Maintenance
of the Dual Data Configuration
Chromatography
GC-MS
Training: Xcalibur Software
Course Objective:
This course is designed to familiarize the student with the operation of Xcalibur software for use in qualitative and quantitative analysis.
Detailed presentations will be given on all Xcalibur modules together with hands on exercises in order to ensure understanding of all the
processes. The students will become familiar with the subjects of method and sequence set-up, data manipulation, automated processing
and report generation. By the end of the course they should be able to apply all software tools for their own purposes.
Training: TraceFinder Software
Course Objective:
TraceFinder is a software package with built-in workflows that have been developed to assist in routine analysis of environmental and food
residue applications. The aim of this training course is to provide new users with the ability to use the software to its full potential. Detailed
presentations will be given on all TraceFinder functionalities together with hands on exercises in order to ensure understanding of all the
processes. The software setup, user selection and all the steps necessary for data collection and processing, data analysis and report
generation will be covered. This training module can be combined with any of the instrument Operations courses on offer.
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Chromeleon Software
Training: Introduction to Chromeleon 7 – Level 1
Course Outline
• Getting started
• Manual and automatic instrument operation
• General navigation
• Collecting data
• Basic sequencing and programming
• Data processing
• Basic calibration
• Specially requested topics (time permitting)
Who Should Attend?
This course has been designed for chromatographers who are new to the Chromeleon workstation
or for existing users who require refresher training.
Training: Next Steps in Chromeleon 7 – Level 2
Course Outline
• Advanced sequencing and programming
• Queries
• Building and managing eWorkflows
• System suitability testing
• Report writing and editing
• Specially requested topics (time permitting)
Who Should Attend?
This course has been designed for chromatographers who are new to the Chromeleon workstation
or for existing users who require refresher training.
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Chromeleon Software
Training: Chromeleon 7.2 – Reporting
Description
The training lasts one day and addresses experienced users, who want to create customized report definition files
taking full advantage ofthe possibilities that are offered by Chromeleon. During the training, a customised report
will be created and it will represent a template for future needs.
The training contains the following topics:
• Report definition files overview
• Use of excel formulas
• Report objects overview
• Use of “unique identifiers”
• Special report variables
Training: Chromeleon 7.2 – IT Administrator
Description
The training lasts one day and addresses employees who need to integrate Chromeleon into the existing IT infrastructure.
The training contains the following topics:
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• Overview of the new architecture in Dionex Chromeleon 7.2.
– Scheduler (Archiving and Backup).
• Installation and Configuration of Dionex Chromeleon 7.2.
– Global Dionex Chromeleon Policies.
– License Management.
– Instrument Configuration.
– User Management (Roles, Privileges and Access Groups).
• Troubleshooting.
– Data Vault Management (with SQL Server).
• The new Enterprise Documentation
Ion Chromatography (IC)
Training: Ion Chromatography New Operator Course
Course Objective:
The course covers basic ion chromatography theory with explanations as to how each component of the
system functions, ensuring the operator can perform basic analysis together with a useful understanding
of ion chromatography instrumentation, including automation.
Courses are grouped to suit customer needs.
Who Should Attend?
The courses are designed to help users who are new to the technique and instrumentation of Ion Chromatography
or for those who want to enhance their theoretical understanding of Ion Chromatography.
Which Systems are Covered?
Thermo Scientific™ Dionex ICS-900, Dionex ICS-1100, Dionex ICS-1600, Dionex ICS-2100, Dionex ICS-3000,
Dionex ICS-5000 systems.
Training: Ion Chromatography Maintenance and Troubleshooting
Course Objective:
The maintenance and troubleshooting courses will assist those undertaking basic maintenance of their
Ion Chromatography systems. The courses cover front line hardware maintenance, column care and
assist the operator in developing troubleshooting skills.
Courses are grouped to suit customer needs.
Who Should Attend?
These courses would suit users who have attended the new operator courses or who are confident
in the use of Ion Chromatography systems and wish to carry out front line maintenance.
Which Systems Are Covered?
Dionex ICS-900, Dionex ICS-1100, Dionex ICS-1600, Dionex ICS-2100, Dionex ICS-3000, Dionex ICS-5000 systems.
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HPLC Systems
Training: New Operator Course for UltiMate 3000
Course Outline
• A basic introduction to HPLC
– Fluid mechanics
– HPLCS Theory
– Method Transfer
• Understanding of the practical aspects of the instrument
– General setup of HPLC systems
– Familiarization with the Thermo Scientific™ Dionex™ UltiMate™ 3000
– Instrument Control
– Practical tips to improve system performance
• Maintenance and Troubleshooting
– Effectively detecting, troubleshooting and rectifying common issues
– Performing instrument maintenance
– Carrying out relevant diagnostic tests
– Experience from hands-on laboratory exercises
– Replacing common HPLC parts
Who Should Attend?
This course has been designed for new users or potential users of
the UltiMate 3000 HPLC, Ultimate 3000 RSLC (Rapid Separation)
and Vanquish systems.
29
HPLC Systems
Training: New Operator Course for Vanquish
Course Outline
• A basic introduction to HPLC
– Fluid mechanics
– HPLCS Theory
– Method Transfer
• Understanding of the practical aspects of the instrument
– General setup of HPLC systems
– Familiarization with the Thermo Scientific™ Vanquish™ system
– Instrument Control
– Practical tips to improve system performance
• Maintenance and Troubleshooting
– Effectively detecting, troubleshooting and rectifying common issues
– Performing instrument maintenance
– Carrying out relevant diagnostic tests
– Experience from hands-on laboratory exercises
– Replacing common HPLC parts
30
On-Site Training Course
Course Description
On-site training provides your company with the opportunity to create a custom made course which meets
your specific requirements. Customized training courses of various lengths and content can be designed
and held in your training facility, laboratory or at one of our locations.
Courses can include any of the topics covered in the previous pages plus:
• Software Features for Photodiode Array Detection
• Software Features for Report Publishing
• Using Chromeleon to Comply with 21 CFR 11
• Advanced Software Features for Fraction Collection
• Ion Chromatography – Carbohydrates in theory and practice
• Ion Chromatography - Anions and Cations
• AutoTrace Solid Phase Extraction
• Electrochemical and CAD Detectors
• New Operator Course for Ultimate 3000 Nano and Capillary LC Systems
• Introduction to Accelerated Solvent Extraction (ASE)
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Training Schedule 2016
COURSE
JAN
FEB
MAR
Chromeleon 7
– Level 1
Chromeleon 7
– Level 2
Vantaa, tuition in English.
Hvidovre, tuition in Danish.
Stockholm, tuition in Swedish.
32
APR
MAY
JUN
JUL
AUG
SEP
OCT
NOV
13
21
2
16
19
9
14
3
DEC
Trace Elemental Analysis
Optimize Your Processes. From AAS to ICP, our experience and intrinsic knowledge
of the market will help you expedite applications and streamline your process for
maximum efficiency and productivity. Whether it’s environmental, petrochemical or
clinical, our experienced instructors will prepare you to operate your instrument and
software with ease.
33
Trace Elemental Analysis
Atomic Absorption Spectroscopy (AAS)
Training: Flame AAS Operations
Course Objective:
This course is designed for the Thermo Scientific AAS Operator and covers all the essential topics related to flame optimization, method
development and efficient operation of the instrument.
The course material includes:
•
•
•
•
•
Absorption and Emission Theory
Hardware: Set up, Use and Optimization
Correction System for Non-Specific Absorptions
Influence of Experimental Parameters
Absorption and Emission Analysis
• Non-Specific Absorption and Chemical Interferences
•Maintenance
• Sample Solubilization
• Quality Control Tests
Training: Furnace AAS Operations
Course Objective:
This course is designed for the Thermo Scientific AAS Operator and covers all the essential topics related to optimization
of a furnace AAS system, method development and efficient operation of the instrument.
The course material includes:
•
•
•
•
•
34
Theory of Absorption
Development of an Analytical Method
Hardware: Set Up, Use and Optimization
Non-Specific Absorption and Matrix Modifiers
Correction System for Non-Specific Absorptions
•Maintenance
• Sample Solubilization
• Influence of Experimental Parameters
• Quality Control Tests
Trace Elemental Analysis
ICP-OES
Training: ICP-OES Operations
Course Objective:
The aim of this is to improve the theoretical knowledge and practical skills of the Thermo Scientific ICP-OES user. The course will cover atomic
spectroscopy theory, plasma related topics, instrument hardware, tuning and method set-up, functionalities of the software package, basic
maintenance and troubleshooting.
The course material includes:
• Atomic Spectroscopy Theory
• Instrument Optimisation
• Identifying and Overcoming Interferences in ICP
35
• Overview of Software Packages available
• Quantitative Analysis
• Instrument Hardware, Maintenance and Troubleshooting
Training Schedule 2016
We currently don’t offer any TEA courses in our facilities in Denmark, Finland, and Sweden. However all the courses described in the brochure
can be offered at customer sites. TEA courses are offered at the following facilities:
• Hemel Hempstead, UK
• Villebon sur Yvette, France
• Dreiech, Germany
• Reinach, Switzerland
For information on training dates and tuition language, please refer to the corresponding brochure.
36
Inorganic Mass Spectrometry
Increase Your Efficiency. Designed to offer both practical and theoretical training, the
Inorganic Mass Spectrometry courses are taught by experienced and certified instructors.
Covering a wide range of techniques our courses ensure that the customer interests and
needs are covered regardless of the uniqueness of their application.
37
Inorganic Mass Spectrometry
ICP-MS
Training: iCAP Q Operations
Course Objective:
This course covers the fundamentals of the Thermo Scientific™ iCAP™ Q ICP-MS system operation and maintenance with a mixture of lectures
and practical sessions. Topics include atomic spectroscopy theory, plasma description, hardware, tuning and method setup, functionalities
of the Thermo Scientific™ Qtegra™ software package, basic maintenance and troubleshooting.
The course material includes:
• Quadrupole ICP-MS Fundamentals
• ICP-MS Analysis and Method Development
• Analytical Issues: Sample Preparation, Matrix Effects
•Calibration
• Data Management and Processing
38
• Qualification and Performances Report
•Maintenance
• Interferences and Solutions
• Flatapole Technology (Q Cell)
• Multi-Elements and Multi-Modes Analysis
Training Schedule 2016
We currently don’t offer any IOMS courses in our facilities in Denmark, Finland, Iceland, Norway and Sweden. However all the courses described
in the brochure can be offered at customer sites. IOMS courses are offered at the following facilities:
• Hemel Hempstead, UK
• Villebon sur Yvette, France
• Dreiech, Germany
• Rodano, Italy
• Bremen, Germany
For information on training dates and tuition language, please refer to the corresponding brochure.
39
Advance Your Knowledge
Stay in touch and receive tailored communications specific to your interests
Join one of our communities to access a wealth of information housed in our Knowledge Libraries.
Each library is a collection of scientific applications literature, videos, webinars and resources
based on your preference.
Scan the QR code or visit www.thermoscientific.com/signup
Information Systems
Water Analysis
Biopharmaceutical
Proteomics
Material Sciences
Chemical
Environmental
Glycomics
Pharmaceutical
Food & Beverage Solutions
GeoSciences
Metabolomics
Clinical Research & Forensics
40
How to Register
For further information or to register on any of the
courses listed, please use the following:
Email:[email protected]
Web: www.thermoscientific.com/eutraining
Sweden:
Thermo Fisher Scientific
Telefonvägen 30
126 26 Hägersten
Phone: +46 8 556 468 00
Fax: +46 8 556 468 08
Denmark:
Thermo Fisher Scientific
Stanholmen 193, 2650 Hvidovre
Phone: +45 7023 6260
Fax: +45 7023 6263
Cancellation Policy
• We reserve the right to cancel any course, 30 calendar days prior to the scheduled start date, due to
insufficient enrollment.
• We reserve the right to change the venue of the course, 30 calendar days prior to the scheduled start date.
• In the event of a venue change, you will be notified by a Thermo Scientific representative.
• Thermo Fisher Scientific will not be responsible for expenses incurred (for example, non-refundable airline
reservations) if the course is cancelled or moved 30 calendar days prior to the scheduled start date.
• Attendee substitutions may be made at any time upon notification of the Training Institute Co-ordinator.
• Enrollment in your desired training course(s) is not guaranteed until receipt of the registration documents and
confirmed method of payment.
Refund Policy
• 100% refund for cancellations received 15+ business days prior to course date.
• 50% refund for cancellations received 10-15 business days prior to course date.
• No refund for cancellations received fewer than 10 business days prior to course date.
• No refund for no-shows.
www.thermoscientific.com
©2015 Thermo Fisher Scientific Inc. All rights reserved. ISO is a trademark of the International Standards Organization. All other trademarks are the property of Thermo Fisher
Scientific and its subsidiaries. This information is presented as an example of the capabilities of Thermo Fisher Scientific products. It is not intended to encourage use of these
products in any manners that might infringe the intellectual property rights of others. Specifications, terms and pricing are subject to change. Not all products are available in all
countries. Please consult your local sales representative for details.
Africa +43 1 333 50 34 0
Australia +61 3 9757 4300
Austria +43 810 282 206
Belgium +32 53 73 42 41
Canada +1 800 530 8447
China 800 810 5118 (free call domestic)
400 650 5118
BR64296-EN 1115S
Denmark +45 70 23 62 60
Europe-Other +43 1 333 50 34 0
Finland +358 9 3291 0200
France +33 1 60 92 48 00
Germany +49 6103 408 1014
India +91 22 6742 9494
Italy +39 02 950 591
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Norway +46 8 556 468 00
Russia/CIS +43 1 333 50 34 0
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Switzerland +41 61 716 77 00
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