DuPont ISCEON MO79 (R-422A) Refrigerant Safety Data Sheet

DuPont ISCEON MO79 (R-422A) Refrigerant Safety Data Sheet
Safety Data Sheet
Sid Harvey item # R42AX24
SDS # Z0331
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
This SDS adheres to the standards and regulatory requirements of the United States and may not meet the regulatory
requirements in other countries.
SECTION 1. PRODUCT AND COMPANY IDENTIFICATION
™
®
Product name
Tradename/Synonym
:
:
DuPont ISCEON MO79 (R-422A) Refrigerant
®
ISCEON MO79
R-422A
MO79
Product Grade/Type
:
ASHRAE Refrigerant number designation: R-422A
Product Use
:
Refrigerant, For professional users only.
Restrictions on use
Manufacturer/Supplier
:
:
Do not use product for anything outside of the above specified uses
DuPont
1007 Market Street
Wilmington, DE 19898
United States of America
Product Information
Medical Emergency
Transport Emergency
:
:
:
+1-800-441-7515 (outside the U.S. +1-302-774-1000)
1-800-441-3637 (outside the U.S. 1-302-774-1139)
CHEMTREC: +1-800-424-9300 (outside the U.S. +1-703-527-3887)
SECTION 2. HAZARDS IDENTIFICATION
Product hazard category
Gases under pressure
Liquefied gas
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
Label content
Pictogram
:
Signal word
: Warning
Hazardous warnings
: Contains gas under pressure; may explode if heated.
Hazardous prevention
measures
: Protect from sunlight. Store in a well-ventilated place.
Other hazards
Misuse or intentional inhalation abuse may lead to death without warning., Vapours are heavier than air and can
cause suffocation by reducing oxygen available for breathing., Rapid evaporation of the liquid may cause
frostbite.
SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS
Component
CAS-No.
Pentafluoroethane (HFC-125)
354-33-6
85.1 %
1,1,1,2-Tetrafluoroethane (HFC-134a)
811-97-2
11.5 %
Isobutane (HC-600a)
75-28-5
3.4 %
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Concentration
Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
SECTION 4. FIRST AID MEASURES
General advice
: Never give anything by mouth to an unconscious person. When symptoms
persist or in all cases of doubt seek medical advice.
Inhalation
: Remove from exposure, lie down. Move to fresh air. Keep patient warm and at
rest. Artificial respiration and/or oxygen may be necessary. Consult a physician.
Skin contact
: In case of contact, immediately flush skin with plenty of water for at least 15
minutes. Take off all contaminated clothing immediately. Consult a physician.
Wash contaminated clothing before re-use. Treat for frostbite if necessary by
gently warming affected area.
Eye contact
: In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Consult a physician if necessary.
Ingestion
: Is not considered a potential route of exposure.
Most important
symptoms/effects, acute
and delayed
: Anaesthetic effects Light-headedness irregular heartbeat with a strange
sensation in the chest, heart thumping, apprehension, feeling of fainting,
dizziness or weakness
Protection of first-aiders
: If potential for exposure exists refer to Section 8 for specific personal protective
equipment.
Notes to physician
: Because of possible disturbances of cardiac rhythm, catecholamine drugs,
such as epinephrine, that may be used in situations of emergency life support
should be used with special caution.
SECTION 5. FIREFIGHTING MEASURES
Suitable extinguishing media
: Use extinguishing measures that are appropriate to local circumstances and
the surrounding environment.
Unsuitable extinguishing
media
: No applicable data available.
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
Specific hazards
: Cylinders are equipped with pressure and temperature relief devices, but may
still rupture under fire conditions. Decomposition may occur. Contact of
welding or soldering torch flame with high concentrations of refrigerant can
result in visible changes in the size and colour of the torch flame. This flame
effect will only occur in concentrations of product well above the
recommended exposure limit. Therefore stop all work and ventilate to
disperse refrigerant vapors from the work area before using any open flames.
This substance is not flammable in air at temperatures up to 100 deg. C (212
deg. F) at atmospheric pressure. However, mixtures of this substance with
high concentrations of air at elevated pressure and/or temperature can
become combustible in the presence of an ignition source. This substance
can also become combustible in an oxygen enriched environment (oxygen
concentrations greater than that in air). Whether a mixture containing this
substance and air, or this substance in an oxygen enriched atmosphere
become combustible depends on the inter-relationship of 1) the temperature
2) the pressure, and 3) the proportion of oxygen in the mixture. In general,
this substance should not be allowed to exist with air above atmospheric
pressure or at high temperatures; or in an oxygen enriched environment. For
example this substance should NOT be mixed with air under pressure for leak
testing or other purposes. Experimental data have also been reported which
indicate combustibility of this substance in the presence of certain
concentrations of chlorine.
Special protective equipment
for firefighters
: In the event of fire, wear self-contained breathing apparatus. Use personal
protective equipment. Wear neoprene gloves during cleaning up work after a
fire.
Further information
: Cool containers/tanks with water spray. Water runoff should be contained
and neutralized prior to release.
SECTION 6. ACCIDENTAL RELEASE MEASURES
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL) sections before proceeding with clean-up.
Use appropriate PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Safeguards (Personnel)
: Evacuate personnel to safe areas. Ventilate area, especially low or enclosed
places where heavy vapours might collect.
Environmental precautions
: Should not be released into the environment.
In accordance with local and national regulations.
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
Spill Cleanup
: Evaporates.
Ventilate area using forced ventilation, especially low or enclosed places
where heavy vapors might collect.
Accidental Release Measures
: Avoid open flames and high temperatures. Self-contained breathing
apparatus (SCBA) is required if a large release occurs.
SECTION 7. HANDLING AND STORAGE
Handling (Personnel)
: Avoid breathing vapours or mist. Avoid contact with skin, eyes and clothing.
Provide sufficient air exchange and/or exhaust in work rooms. For personal
protection see section 8.
Handling (Physical Aspects)
: Contact with chlorine or other strong oxidizing agents should also be avoided.
Dust explosion class
: Not applicable
Storage
: Valve protection caps and valve outlet threaded plugs must remain in place
unless container is secured with valve outlet piped to use point. Do not drag,
slide or roll cylinders. Use a suitable hand truck for cylinder movement. Use a
pressure reducing regulator when connecting cylinder to lower pressure
(<3000 psig) piping or systems. Never attempt to lift cylinder by its cap. Use a
check valve or trap in the discharge line to prevent hazardous back flow into
the cylinder. Cylinders should be stored upright and firmly secured to
prevent falling or being knocked over.
Separate full containers from empty containers. Keep at temperature not
exceeding 52°C. Do not store near combustible materials. Avoid area where
salt or other corrosive materials are present.
The product has an indefinite shelf life when stored properly.
Storage period
: > 10 yr
Storage temperature
: < 52 °C (< 126 °F)
SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Engineering controls
: Normal ventilation for standard manufacturing procedures is generally
adequate. Local exhaust should be used when large amounts are released.
Mechanical ventilation should be used in low or enclosed places. Refrigerant
Concentration monitors may be necessary to determine vapor concentrations
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
in work areas prior to use of torches or other open flames, or if employees are
entering enclosed areas.
Personal protective equipment
Respiratory protection
: Under normal manufacturing conditions, no respiratory protection is required
when using this product.
Hand protection
: Additional protection: Impervious gloves
Eye protection
: Wear safety glasses with side shields. Additionally wear a face shield where
the possibility exists for face contact due to splashing, spraying or airborne
contact with this material.
Protective measures
: Self-contained breathing apparatus (SCBA) is required if a large release
occurs.
Exposure Guidelines
Exposure Limit Values
Pentafluoroethane (HFC-125)
AEL *
(DUPONT)
1,000 ppm
8 & 12 hr. TWA
1,1,1,2-Tetrafluoroethane (HFC-134a)
AEL *
(DUPONT)
1,000 ppm
8 & 12 hr. TWA
Isobutane (HC-600a)
TLV
1,000 ppm
STEL
(ACGIH)
* AEL is DuPont's Acceptable Exposure Limit. Where governmentally imposed occupational exposure limits which are
lower than the AEL are in effect, such limits shall take precedence.
SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Physical state
Form
Color
: gaseous
: Liquefied gas
: colourless
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
Odor
: slight, ether-like
Odor threshold
: No applicable data available.
pH
: neutral
Melting point/freezing point
: Melting point/range
Not available for this mixture.
Boiling point/boiling range
: Boiling point
-46.5 °C (-51.7 °F)
Flash point
:
Evaporation rate
: No applicable data available.
Flammability (solid, gas)
:
Not applicable
Upper explosion limit
:
Method: None per ASTM E681
Lower explosion limit
:
Method: None per ASTM E681
Vapor pressure
: 12,757 hPa at 25 °C (77 °F)
Vapor density
: 4.0 at 25°C (77°F) and 1013 hPa (Air=1.0)
Specific gravity (Relative
density)
: 1.14 at 25 °C (77 °F) at (1,013 hPa)
Water solubility
: 1.0 g/l at 25 °C (77 °F)
Solubility(ies)
: No applicable data available.
Partition coefficient: noctanol/water
: No applicable data available.
Auto-ignition temperature
:
No applicable data available.
Decomposition temperature
:
No applicable data available.
Viscosity, kinematic
:
No applicable data available.
Viscosity
:
No applicable data available.
does not flash
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
% Volatile
: 100 %
SECTION 10. STABILITY AND REACTIVITY
Reactivity
Chemical stability
:
:
No applicable data available.
Stable under recommended storage conditions.
Possibility of hazardous
reactions
Conditions to avoid
:
Polymerization will not occur.
:
The product is not flammable in air under ambient conditions of temperature
and pressure. When pressurised with air or oxygen, the mixture may become
flammable. Certain mixtures of HCFCs or HFCs with chlorine may become
flammable or reactive under certain conditions.
Incompatible materials
:
Alkali metals Alkaline earth metals, Powdered metals, Powdered metal salts
Hazardous decomposition
products
:
Decomposition products are hazardous., This material can be decomposed
by high temperatures (open flames, glowing metal surfaces, etc.) forming
hydrofluoric acid and possibly carbonyl fluoride., These materials are toxic
and irritating., Avoid contact with decomposition products
SECTION 11. TOXICOLOGICAL INFORMATION
Pentafluoroethane (HFC-125)
Inhalation 4 h LC50
:
> 800000 ppm , Rat
Inhalation No Observed
Adverse Effect
Concentration
Inhalation Low Observed
Adverse Effect
Concentration (LOAEC)
Skin sensitization
:
100000 ppm , Dog
Cardiac sensitization
:
75000 ppm , Dog
Cardiac sensitization
:
Does not cause respiratory sensitisation., human
Repeated dose toxicity
:
Inhalation
Rat
gas
NOAEL: > 50000,
No toxicologically significant effects were found.
Carcinogenicity
:
Not classifiable as a human carcinogen.
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
Overall weight of evidence indicates that the substance is not
carcinogenic.
Mutagenicity
:
Animal testing did not show any mutagenic effects.
Evidence suggests this substance does not cause genetic damage in
cultured mammalian cells.
Did not cause genetic damage in cultured bacterial cells.
Reproductive toxicity
:
No toxicity to reproduction
Animal testing showed no reproductive toxicity.
Teratogenicity
:
Animal testing showed no developmental toxicity.
Further information
:
Cardiac sensitisation threshold limit : 490000 mg/m3
:
> 567000 ppm , Rat
:
40000 ppm , Dog
Cardiac sensitization
1,1,1,2-Tetrafluoroethane (HFC-134a)
Inhalation 4 h LC50
Inhalation No Observed
Adverse Effect
Concentration
Inhalation Low Observed
Adverse Effect
Concentration (LOAEC)
Skin irritation
:
80000 ppm , Dog
Cardiac sensitization
:
No skin irritation, Rabbit
Eye irritation
:
No eye irritation, Rabbit
Skin sensitization
:
Does not cause skin sensitisation., Guinea pig
Does not cause respiratory sensitisation., Rat
Repeated dose toxicity
:
Inhalation
Rat
gas
NOAEL: 50000,
No toxicologically significant effects were found.
Carcinogenicity
:
Not classifiable as a human carcinogen.
Overall weight of evidence indicates that the substance is not
carcinogenic.
Mutagenicity
:
Animal testing did not show any mutagenic effects.
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
Tests on bacterial or mammalian cell cultures did not show mutagenic
effects.
Reproductive toxicity
:
No toxicity to reproduction
No effects on or via lactation
Animal testing showed no reproductive toxicity.
Teratogenicity
:
Animal testing showed no developmental toxicity.
Further information
:
Cardiac sensitisation threshold limit : 334000 mg/m3
Isobutane (HC-600a)
Inhalation 4 h LC50
:
276808 ppm , Rat
The toxicological data has been taken from products of similar
composition.
Inhalation 4 h LC50
:
> 31 mg/l , Rat
Inhalation Low Observed
Adverse Effect
Concentration (LOAEC)
Inhalation No Observed
Adverse Effect
Concentration
Dermal
:
50000 ppm , Dog
Cardiac sensitization
:
25000 ppm , Dog
Cardiac sensitization
:
Not applicable
Oral
:
Not applicable
Skin irritation
:
No skin irritation, Not tested on animals
Not expected to cause skin irritation based on expert review of the
properties of the substance.
Eye irritation
:
No eye irritation, Not tested on animals
Not expected to cause eye irritation based on expert review of the
properties of the substance.
Skin sensitization
:
Not tested on animals
Not expected to cause sensitization based on expert review of the
properties of the substance.
Repeated dose toxicity
:
Inhalation
Rat
No toxicologically significant effects were found.
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
Mutagenicity
:
Tests on bacterial or mammalian cell cultures did not show mutagenic
effects.
Animal testing did not show any mutagenic effects.
Reproductive toxicity
:
No toxicity to reproduction
Animal testing showed no reproductive toxicity.
Teratogenicity
:
Animal testing showed no developmental toxicity.
Further information
:
Cardiac sensitisation threshold limit : 118.9 mg/m3
Carcinogenicity
The carcinogenicity classifications for this product and/or its ingredients have been determined according
to HazCom 2012, Appendix A.6. The classifications may differ from those listed in the National Toxicology
Program (NTP) Report on Carcinogens (latest edition) or those found to be a potential carcinogen in the
International Agency for Research on Cancer (IARC) Monographs (latest edition).
None of the components present in this material at concentrations equal to or greater than 0.1% are listed
by IARC, NTP, or OSHA, as a carcinogen.
SECTION 12. ECOLOGICAL INFORMATION
Aquatic Toxicity
Pentafluoroethane (HFC-125)
96 h LC50
:
Oncorhynchus mykiss (rainbow trout) 450 mg/l
Information given is based on data obtained from similar substances.
96 h ErC50
:
Algae 142 mg/l
Information given is based on data obtained from similar substances.
72 h NOEC
:
Pseudokirchneriella subcapitata (green algae) 13.2 mg/l
Information given is based on data obtained from similar substances.
48 h EC50
:
Daphnia magna (Water flea) 980 mg/l
Information given is based on data obtained from similar substances.
1,1,1,2-Tetrafluoroethane (HFC-134a)
96 h LC50
:
Oncorhynchus mykiss (rainbow trout) 450 mg/l
96 h ErC50
:
Algae 142 mg/l
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
Information given is based on data obtained from similar substances.
72 h NOEC
:
Pseudokirchneriella subcapitata (green algae) 13.2 mg/l
Information given is based on data obtained from similar substances.
48 h EC50
:
Daphnia magna (Water flea) 980 mg/l
Isobutane (HC-600a)
96 h LC50
:
Fish 24.11 mg/l
72 h EC50
:
Algae 7.71 mg/l
48 h EC50
:
Daphnia (water flea) 14.22 mg/l
SECTION 13. DISPOSAL CONSIDERATIONS
Waste disposal methods Product
: Can be used after re-conditioning. Recover by distillation or remove to a
permitted waste disposal facility. Comply with applicable Federal,
State/Provincial and Local Regulations.
Contaminated packaging
: Empty pressure vessels should be returned to the supplier.
SECTION 14. TRANSPORT INFORMATION
DOT
IATA_C
UN number
: 1078
Proper shipping name
: Refrigerant gases, n.o.s. (1,1,1,2-Tetrafluoroethane,
Pentafluoroethane)
: 2.2
: 2.2
: 1078
Class
Labelling No.
UN number
Proper shipping name
IMDG
Class
Labelling No.
UN number
: Refrigerant gas, n.o.s. (1,1,1,2-Tetrafluoroethane,
Pentafluoroethane)
: 2.2
: 2.2
: 1078
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
Proper shipping name
Class
Labelling No.
: REFRIGERANT GAS, N.O.S. (1,1,1,2-Tetrafluoroethane,
Pentafluoroethane)
: 2.2
: 2.2
SECTION 15. REGULATORY INFORMATION
SARA 313 Regulated
Chemical(s)
: This material does not contain any chemical components with known CAS
numbers that exceed the threshold (De Minimis) reporting levels established
by SARA Title III, Section 313.
PA Right to Know
Regulated Chemical(s)
: Substances on the Pennsylvania Hazardous Substances List present at a
concentration of 1% or more (0.01% for Special Hazardous Substances):
Isobutane (HC-600a)
NJ Right to Know
Regulated Chemical(s)
: Substances on the New Jersey Workplace Hazardous Substance List present
at a concentration of 1% or more (0.1% for substances identified as
carcinogens, mutagens or teratogens): Isobutane (HC-600a)
California Prop. 65
: Chemicals known to the State of California to cause cancer, birth defects or
any other harm: none known
SECTION 16. OTHER INFORMATION
ISCEON is a registered trademark of E. I. du Pont de Nemours and Company
DuPont's registered trademark
Before use read DuPont's safety information.
For further information contact the local DuPont office or DuPont's nominated distributors.
®
Revision Date
: 04/01/2015
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the
date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage,
transportation, disposal and release and is not to be considered a warranty or quality specification. The information
relates only to the specific material designated and may not be valid for such material used in combination with any
other materials or in any process, unless specified in the text.
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Safety Data Sheet
DuPont™ ISCEON® MO79 (R-422A) Refrigerant
Version 2.0
Revision Date 04/01/2015
Ref. 130000027388
Significant change from previous version is denoted with a double bar.
14 / 14
<[UPON)?
The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
Page
DuPont
Material Safety Data Sheet
DuPont (TM) ISCEON(R) M079
Revised 20-SEP-2005
6208FR
CHEMICAL PRODUCT/COMPANY IDENTIFICATION
Material Identification
Molecular Weight
114
Tradenames and Synonyms
R-422A
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont Fluoroproducts
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information
Transport Emergency
Medical Emergency
1-800-441-7515 (outside the U.S.
302-774-1000)
CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
1-800-441-3637 (outside the U.S.
302-774-1000)
COMPOSITION/INFORMATION ON INGREDIENTS
Components
Material
1, 1, 1, 2-Tetrafluoroethane
Pentafluoroethane
Isobutane
CAS Number
811-97-2
354-33-6
75-28-5
%
11.5
85.1
3.4
HAZARDS IDENTIFICATION
Potential Health Effects
Gross overexposure by inhalation may cause central nervous
system depression with dizziness, confusion, incoordination,
drowsiness or unconsciousness; irregular heart beat with a
strange sensation in the chest, "heart thumping",
apprehension, lightheadedness, feeling of fainting,
dizziness, weakness, sometimes progressing to loss of
consciousness and death; and suffocation, if air is
displaced by vapors.
Skin contact with liquid or escaping vapor may cause
frostbite. Significant skin per.meation, and systemic
1
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DuPont
Material Safety Data Sheet
Page
(HAZARDS IDENTIFICATION - Continued)
toxicity, after contact appears unlikely. There are no
reports of human sensitization.
"Frostbite-like" effects may occur if liquid or escaping
vapors contact the eyes.
Increased susceptibility to the effects of overexposure to
this product may be observed in persons with pre-existing
disease of the central nervous system or cardiovascular
system.
Carcinogenicity Infor.mation
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARe, NTP, OSHA or ACGIH
as a carcinogen.
FIRST AID MEASURES
First Aid
INHALATION
If inhaled, immediately remove to fresh air. Keep person calm.
If not breathing, give artificial respiration.
If breathing is
difficult, give oxygen. Call a physician.
SKIN CONTACT
Flush area with lukewarm water. Do not use hot water.
frostbite has occurred, call a physician.
If
EYE CONTACT
In case of contact, immediately flush eyes with plenty of water
for at least 15 minutes. Call a physician.
INGESTION
Ingestion is not considered a potential route of exposure.
Notes to Physicians
Because of possible disturbances of cardiac rhythm, catecholamine
drugs, such as epinephrine, should only be used with special
caution in situations of emergency life support.
2
6208FR
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DuPont
Material Safety Data Sheet
FIRE FIGHTING MEASURES
Flammable Properties
Flash Point,:
,No Flash point
Flammable Limits in Air, % by Volume:
LEL,,:,None per ASTM E681-98
UEL,,: ,None per ASTM E681-98
Autoignition,: ,Not determined
Fire and Explosion Hazards:
Cylinders may rupture under fire conditions.
may occur.
Decomposition
Contact of welding or soldering torch flame with high
concentrations of refrigerant can result in visible changes
in the size and color of torch flames.
This flame effect
will only occur in concentrations of product well above the
recommended exposure limit, therefore stop all work and
ventilate to disperse refrigerant vapors from the work area
before using any open flames.
This product is not flammable in air at temperatures up to
100 deg. C (212 deg. F) at atmospheric pressure. However,
mixtures of this product with high concentrations of air at
elevated pressure and/or temperature can become combusti ble
in the presence of an ignition source.
This product can
also become combustible in an oxygen enriched environment
(oxygen concentrations greater than that in air). Whether a
mixture containing this product and air, or this product in
an oxygen enriched atmosphere becomes combustible depends on
the inter-relationship of 1) the temperature 2) the
pressure, and 3) the proportion of oxygen in the mixture.
In general, this product should not be allowed to exist with
air above atmospheric pressure or at high temperatures, or
in an oxygen-enriched environment.
For example:
This
product should NOT be mixed with air under pressure for leak
testing or other purposes.
Experimental data have also been reported which indicate
combustibility of HFC-134a, a component in this blend, in
the presence of chlorine.
Extinguishing Media
Use media appropriate for surrounding material.
Fire Fighting Instructions
Cool cylinders with water spray or fog.
Self-contained
breathing apparatus (SCBA) is required if cylinders rupture
and contents are released under fire conditions. Water
runoff should be contained and neutralized prior to release.
3
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DuPont
Material Safety Data Sheet
Page
ACCIDENTAL RELEASE MEASURES
Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Initial Containment
Prevent material from entering sewers, waterways, or low areas.
Spill Clean Up
Recover free liquid for reuse or reclamation.
Accidental Release Measures
Ventilate area using forced ventilation, especially in low
or enclosed places where heavy vapors might collect. Remove
open flames.
Use self-contained breathing apparatus (SCBA)
for large spills or releases.
HANDLING AND STORAGE
Handling (Personnel)
Avoid breathing vapor. Avoid liquid contact with eyes and
skin. Use with sufficient ventilation to keep employee
exposure below recommended limits. Contact with chlorine or
other strong oxidizing agents should also be avoided.
See
Fire and Explosion Data section.
Handling (Physical Aspects)
Keep container tightly closed.
Storage
Store in a cool, dry place.
Store below 52 C (125 F).
EXPOSURE CONTROLS/PERSONAL PROTECTION
Engineering Controls
Avoid breathing vapors. Avoid contact with skin or eyes.
Use with sufficient ventilation to keep employee exposure
below the recommended exposure limit.
Local exhaust should
be used if large amounts are released. Mechanical
ventilation should be used in low or enclosed places.
4
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DuPont
Material Safety Data Sheet
Page
5
(EXPOSURE CONTROLS/PERSONAL PROTECTION - Continued)
Refrigerant concentration monitors may be necessary to
deter.mine vapor concentrations in work areas prior to use of
torches or other open flames, or if employees are entering
enclosed areas.
Personal Protective Equipment
Impervious gloves should be used to avoid prolonged or
repeated exposure.
Chemical splash goggles should be
available for use as needed to prevent eye contact. Under
normal manufacturing conditions, no respiratory protection
is required when using this product.
Self-contained
breathing apparatus (SCBA) is required if a large release
occurs.
Exposure Guidelines
Applicable Exposure Limits
1, 1, 1, 2-Tetrafluoroethane
PEL
(OSHA)
TLV
(ACGIH)
AEL • (DuPont)
WEEL (AIHA)
None Established
None Established
1000 ppm, 8 & 12 Hr. TWA
1000 ppm, 8 Hr. TWA
Pentafluoroethane
PEL
TLV
AEL •
WEEL
(OSHA)
(ACGIH)
(DuPont)
(AIHA)
None Established
None Established
1000 ppm, 8 & 12 Hr. TWA
1000 ppm, 4900 mg/m3, 8 Hr. TWA
Isobutane
TLV
(ACGIH)
: 1000 ppm, 8 Hr. TWA
* AEL is DuPont's Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
PHYSICAL AND CHEMICAL PROPERTIES
Physical Data
C) @ atmospheric pressure
77 F (25 C)
1) @ 77F (25 C)
Boiling Point:
Vapor Pressure:
Vapor Density:
% Volatile:
Solubility in Water:
-52 F (-47
185 psia @
4.0 (Air
100%
-0.1 wt% @
pH:
Neutral
Odor:
Slight Ether-like
Form:
Liquified Gas
Colorless
Color:
Specific Gravity:
Density:
77 F (25 C)
1.14 @ 77 F (25 C)
Liquid = 70.9 1hs/eu ft @ 77 F {25 C
620BFR
DuPont
Material Safety Data Sheet
Page
STABILITY AND REACTIVITY
Chemical Stability
Stable.
Incompatibility with Other Materials
Incompatible with alkali or alkaline earth metals - powdered
AI, Zn, Be, etc.
Decomposition
Decomposition products are hazardous.
This material can be
decomposed by high temperatures (open flames, glowing metal
surfaces, etc.) forming hydrofluoric acid and possibly
carbonyl fluoride.
These materials are toxic and irritating.
avoided.
Contact should be
Polymerization
Polymerization will not occur.
TOXICOLOGICAL INFORMATION
Animal Data
1,1,1,2-Tetrafluoroethane (HFC-134a):
Inhalation 4 hour ALe:
567,000 ppm in rats
A short duration spray of HFC-134a vapor produced very
slight eye irritation. Animal testing indicates HFC-134a is
a slight skin irritant, but not a skin sensitizer.
Single inhalation exposures caused lethargy, narcosis,
increased respiratory difficulties, incoordination, tremors,
lack of response to sound and salivation; following the
cessation of treatment most animals returned to nor.mal.
Death occurred at very high concentrations (> 500,000 ppm)
in some animals.
Single exposure to near lethal doses
caused pulmonary edema.
Repeated exposure caused increased
weight of the adrenals, liver and spleen, and decreased
uterine and prostate weight.
Repeated dosing of higher
concentrations caused temporary tremors and incoordination.
In other repeated exposure studies with rats exposed to
concentrations of 49,500 ppm, and mice exposed up to 300,000
ppm, no significant differences were seen between exposed
and control animals; in a different study mice exposed to
concentrations up to 350,000 ppm there were mortalities,
tremors and incoordination in the 350,000 ppm group.
Head
shaking and salivation occurred in dogs exposed to 150,000
6
6208FR
DuPont
Material Safety Data Sheet
Page
(TOXICOLOGICAL INFORMATION - Continued)
ppm for 7 days; other parameters such as hematology,
clinical chemical, body weight, and food consumption were
unaffected. Testicular hormonal levels were affected in
male rats and pituitary hor.mone changes occurred in female
rats in a 2-week inhalation study but there were no other
treatment-related changes.
In a long-ter.m inhalation study
in rats and mice no treatment-related effects were seen. No
signs of neurological disturbances were seen in an
inhalation study to access neurotoxicity in rats.
Cardiac sensitization, a potentially fatal disturbance of
heart rhythm associated with a heightened sensitivity to the
action of epinephrine, occurred in dogs at concentrations of
75,000 ppm and higher.
In a two-year inhalation study, HFC-134a, at a concentration
of 50,000 ppm, produced an increase in late-occurring benign
testicular tumors, testicular hyperplasia and testicular
weight. The no-effect-level for this study was 10,000 ppm.
Animal data show slight fetotoxicity but only at exposure
levels producing other toxic effects in the adult animal.
Reproductive data on male mice and male or female rats show
no change in reproductive performance.
Tests have shown
that HFC-134a does not cause genetic damage in bacterial or
mammalian cell cultures, or in animals.
In animal testing
testing, HFC-134a has not caused permanent genetic damage in
reproductive cells of mammals (has not produced heritable
genetic damage).
Pentafluoroethane:
Inhalation 4 hour, ALC, rat: > 709,000 ppm
This material has not been tested for eye irritation.
This material has not been tested for skin irritation or
sensitization.
Single exposure to high doses by inhalation caused:
Lethargy.
Labored breathing. Weak cardiac sensitization, a
potentially fatal disturbance of heart rhythm caused by a
heightened sensitivity to the action of epinephrine.
Lowest-Observed-Adverse-Effect-Level for cardiac
sensitization: 100,000 ppm. Repeated exposure caused: No
significant toxicological effects.
NO-Observed-Adverse-Effect-Level (NOAEL); 50,000 ppm
No animal data are available to define the following effects
of this material: carcinogenicity, reproductive toxicity. In
animal testing this material has not caused developmental
toxicity. Tests have shown that this material does not cause
genetic damage in bacterial or mammalian cell cultures, or
in animals.
This material has not been tested for its
ability to cause permanent genetic damage in reproductive
7
DuPont
Material Safety Data Sheet
6208FR
Page
(TOXICOLOGICAL INFORMATION - Continued)
cells of mammals (not tested for heritable genetic damage).
Isobutane:
Inhalation 15 minute LeSO:
570,000 ppm in rats
The compound is untested for skin or eye irritancy, and for
animal sensitization.
Inhalation:
Exposure to large amounts caused central
nervous system depression and anesthesia, constriction of
upper airways and depression of the heart with lowered blood
pressure.
No animal test reports are available to define carcinogenic,
developmental, or reproductive hazards.
This material does not produce genetic damage in bacterial
cell cultures but has not been tested in animals.
ECOLOGICAL INFORMATION
Ecotoxicological Information
Aquatic Toxicity:
1, 1,1, 2-Tetrafluoroethane:
48 hour LCSO - daphnia magna:
96 hour LCSO - rainbow trout:
980 mg/L
450 mg/L
DISPOSAL CONSIDERATIONS
Waste Disposal
Treatment, storage, transportation, and disposal must be in
accordance with applicable Federal, State/Provincial, and Local
regulations.
TRANSPORTATION INFORMATION
# Shipping Information
DOT/IMO
Proper Shipping Name
Hazard Class
No.
Reportable quantity
Marine Pollutant
UN
Refrigerant Gas, N.D.S.
(l,1,l,2-Tetrafluoroethane and
Pentafluoroethane)
2.2
1078
No
No
8
620BFR
DuPont
Material Safety Data Sheet
Page
(TRANSPORTATION INFORMATION - Continued)
DOT/IMO Label
: Nonflammable Gas
REGULATORY INFORMATION
u.s. Federal Regulations
TSCA Inventory Status
: Listed.
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute
Chronic
Fire
Reactivity
Pressure
Yes
Yes
No
No
Yes
OTHER INFORMATION
NFPA, NPCA-HMIS
NPCA-HMIS Rating
Health
Flammability
Reactivity
1
o
1
Personal Protection rating to be supplied by user depending on use
conditions.
The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS
>
Address
Telephone
MSDS Coordinator
DuPont Fluoroproducts
Wilmington, DE 19898
(BOO) 441-7515
# Indicates updated section.
This information is based upon technical information believed to be
reliable.
It is Subject to revision as additional knowledge and
experience is gained.
End of MSDS
9
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