PI, OncoScan CNV Array - Thermo Fisher Scientific

PI, OncoScan CNV Array - Thermo Fisher Scientific
Storage, Handling and Stability
The probe array consists of a square glass substrate mounted in a plastic cartridge
(Figure 1). The glass contains an array of oligonucleotides that, when mounted,
is on the inner glass surface. A chamber in the plastic housing directly under the
glass acts as a reservoir where hybridization and washing occur.
PackageInsert
Although the inner glass surface of the array is protected, any contamination
or scratches on the outer surface of the glass can compromise the accuracy of
the scan. Avoid touching the surface of the glass with your fingers. Skin oils and
other substances, such as lotions or ink, can fluoresce. If the surface of the glass
is noticeably dirty, it can be carefully cleaned with a non-abrasive laboratory
tissue.
OncoScan CNV Array
®
Figure 1. GeneChip® Probe Array
For Research Use Only
Not for use in diagnostic procedures.
Plastic cartridge
Notch
Septa
Front
Introduction
The OncoScan CNV FFPE Assay Kit includes the OncoScan CNV Arrays and the
OncoScan® CNV Reagent Kit. The OncoScan CNV FFPE Assay Kit detects genome
wide copy number gains and losses, as well as loss of heterozygosity (LOH)
including copy neutral LOH using limited DNA from Formalin-Fixed ParaffinEmbedded (FFPE) samples of various ages. The OncoScan CNV Array contains
328,000 tags, in triplicate, that hybridize to amplified DNA target generated
during the assay.
®
®
Probes on a
glass substrate
Back
OncoScan® CNV FFPE Assay Kit is for research use only and not intended for
use in diagnosis of disease. Please refer to www.affymetrix.com for a list of
supporting manuals for assay and data analysis procedures.
The GeneChip® arrays should be stored at 2° to 8°C. Refer to the expiration date
on the package label. Do not use probe arrays or reagents after the expiration
date.
Instrumentation and Software Required
1. GeneChip® Scanner 3000 7G
2. GeneChip® Fluidics Station 450
3. GeneChip® Hybridization Oven 645
4. GeneChip® Command Console® Software (AGCC)
5. OncoScan® Console Software (analysis) (AGCC)
Limited License
Ordering Information
P/N
Product Name
Description
902695
OncoScan® CNV FFPE Assay Kit
Array and Reagent Kit Bundle
Sufficient for 24 samples and includes
48 OncoScan® CNV Arrays
902693
OncoScan® CNV Training Kit
Array and Reagent Kit Bundle
Sufficient for 18 samples and includes
36 OncoScan® CNV Arrays
Affymetrix® products can be purchased directly from Affymetrix in the United
States, and many European and Asian countries. For all other territories,
please view a list of our distribution partners, which can be located at:
www.affymetrix.com/site/contact/index.affx.
Precautions
1. ONCOSCAN CNV ARRAYS ARE FOR RESEARCH USE ONLY; NOT FOR
DIAGNOSTIC PROCEDURES.
2. Avoid microbial contamination, which may cause erroneous results.
3. WARNING: All biological specimens and materials with which they
come into contact should be handled as if capable of transmitting
infection and disposed of with proper precautions in accordance with
federal, state, and local regulations. This includes adherence to the
OSHA Bloodborne Pathogens Standard (29 CFR 1910.1030) for bloodderived and other samples governed by this act. Never pipet by
mouth. Avoid specimen contact with skin and mucous membranes.
4. CAUTION: Exercise standard precautions when obtaining, handling, and
disposing of potentially carcinogenic reagents.
5. Exercise care to avoid cross-contamination of samples during all steps of this
procedure, as this may lead to erroneous results.
6. Use powder-free gloves whenever possible to minimize introduction of
powder particles into sample or probe array cartridges.
Affymetrix hereby grants to buyer a non-exclusive, non-transferable, nonsublicensable license to Affymetrix’ Core Product IP to use the product(s), but only
in accordance with the product labels, inserts, manuals and written instructions
provided by Affymetrix. “Core Product IP” is the intellectual property owned or
controlled by Affymetrix as of the shipment date of a product that covers one or
more features of the product that are applicable in all applications of the product
that are in accordance with the product labels, inserts, manuals and written
instructions provided by Affymetrix. The license granted herein to buyer to the
Core Product IP expressly excludes any use that: (i) is not in accordance with the
product labels, inserts, manuals and written instructions provided by Affymetrix,
(ii) requires a license to intellectual property that covers one or more features
of a product that are only applicable within particular fields of use or specific
applications, (iii) involves reverse engineering, disassembly, or unauthorized
analysis of the product and/or its methods of use, or (iv) involves the re-use of a
consumable product. Buyer understands and agrees that except as expressly set
forth, no right or license to any patent or other intellectual property owned or
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implication, estoppel or otherwise. In particular, no right or license is conveyed
or implied to use any product provided hereunder in combination with a product
or service not provided, licensed or specifically recommended by Affymetrix
for such use. Furthermore, buyer understands and agrees that buyer is solely
responsible for determining whether buyer possesses all intellectual property
rights that may be necessary for buyer’s specific use of the product, including
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Contact Information
Patents
Affymetrix, Inc.
Products may be covered by one or more of the following patents: U.S. Patent
Nos. 5,445,934; 5,744,305; 5,945,334; 6,140,044; 6,399,365; 6,551,817;
6,733,977; 7,629,164; 7,790,389 and D430,024 and other U.S. or foreign
patents. Products are manufactured and sold under license from OGT under
5,700,637.
3420 Central Expressway
Santa Clara, CA 95051 USA
E-mail: [email protected]
Tel: 1-888-362-2447 (1-888-DNA-CHIP)
Fax: 1-408-731-5441
Affymetrix UK Ltd
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Wycombe Lane, Wooburn Green,
High Wycombe HP10 0HH
United Kingdom
E-mail: [email protected]
UK and Others Tel: +44 (0) 1628 552550
France Tel: 0800919505
Germany Tel: 01803001334
Fax: +44 (0) 1628 552585
Trademarks
Affymetrix®, Axiom®, Command Console®, CopyView™, CytoScan®, DMET™,
GeneAtlas®, GeneChip®, GeneChip–compatible™, GeneTitan®, Genotyping
Console™, myDesign™, NetAffx®, OncoScan®, Powered by Affymetrix™,
PrimeView®, Procarta®, ViewRNA®, and QuantiGene® are trademarks or
registered trademarks of Affymetrix, Inc. All other trademarks are the property
of their respective owners.
Copyright
©2015 Affymetrix, Inc. All rights reserved.
Affymetrix Japan, K. K.
ORIX Hamamatsucho Bldg, 7F
1-24-8 Hamamatsucho, Minato-ku
Tokyo 105-0013, Japan
Tel: +81-3-6430-4020
Fax: +81-3-6430-4021
E-mail: [email protected]
Please visit our web site for international distributor contact information
www.affymetrix.com
OncoScan® CNV Array P/N 703328 Rev. 1
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