BioLogic DuoFlow Systems
™
A family of high-resolution chromatography systems.
BioLogic DuoFlow Systems
The BioLogic DuoFlow family of chromatography systems offers flexibility with multiple
system configurations, many optional upgrades, and a common software platform that
is intuitive and easy to follow. Key features of all systems include:
I
Friendly, intuitive software
I
Onscreen help menu that is easily accessible
and provides extensive explanations, diagrams,
and a system and application troubleshooting
guide
I
Modular hardware components that allow for
optimal placement of valves, detectors, and
columns to minimize dead volumes; modularity
makes the systems easily upgradable to fit all
applications and budgets
I
Flow rate flexibility — the workstation is configured
with an F10 or F40 pump to accommodate
different flow rates; optional pump kits provide
convenient reconfiguration at any time
I
I
I
I
Scouting wizard that provides quick and easy
setup to optimize a purification method of a target
molecule by changing a variable (e.g., buffer pH,
flow rate, or length of step) over multiple runs
automatically
I
Method templates that allow easy method creation
with predefined chromatography methods for all
common chromatography applications, including
affinity, ion exchange, chromatofocusing,
hydrophobic interaction, hydroxyapatite, size
exclusion, and multidimensional chromatography
I
Trace Compare function that permits overlay
of any number of different chromatograms for
comparison of runs performed under different
conditions (e.g., pH, flow rate, or buffer gradients)
I
Ability to connect auxiliary pump for large
sample loading (e.g., Econo™ gradient pump or
Model EP-1 Econo pump)
Endless valving options to perform diverse
applications: reverse-flow chromatography,
column switching, tandem chromatography,
multidimensional chromatography, buffer scouting,
and large sample loading
I
Ability to integrate up to 2 external detectors
(e.g., refractive index or fluorescence detectors)
I
Optional EZLogic™ integration software that offers
additional data analysis functions to the BioLogic
DuoFlow software
A starter kit and UNO® Q1 column — easy-tofollow instructions enable the user to learn how to
run a sample under controlled conditions
I
Optional BioFrac™ ice bath/microplate rack to
keep samples cool
I
Coldroom compatibility
Make-Before-Break (MBB) technology in all
automated valves to provide uninterrupted flow
(when valve is switching positions), which
eliminates baseline interference
BioLogic DuoFlow
Systems
BioLogic DuoFlow 10 System
10 ml/min flow rate at 3,500 psi
(233 bar, 23.3 MPa)
BioLogic DuoFlow 40 System
40 ml/min flow rate at 1,000 psi
(66 bar, 6.6 MPa)
Both systems include:
I
Standard UV detector with fixed 254
and 280 nm filters; additional drop-in
expansion filters (214, 365, 405, and
436 nm) are available
I
Conductivity monitor that monitors salt
concentration to ensure reliable gradient
formation and pump functions
I
BioFrac fraction collector that offers
flexibility with 15 different rack options to
collect microliter to liter sample volumes
I
Workstation with dual-piston pumps
and valving connections — able to
connect up to 3 low-pressure and
3 high-pressure valves
I
Gradient mixer to ensure accurate
gradient formation
I
AVR7-3 automated injection valve with
MBB technology
BioLogic DuoFlow QuadTec 10 System
10 ml/min flow rate at 3,500 psi
(233 bar, 23.3 MPa)
BioLogic DuoFlow QuadTec 40 System
40 ml/min flow rate at 1,000 psi
(66 bar, 6.6 MPa)
Both systems include:
I
Conductivity monitor that ensures reliable
gradient formation and pump functions
I
BioFrac fraction collector that offers
flexibility with 15 different rack options to
collect microliter to liter sample volumes
I
BioLogic DuoFlow
QuadTec™ Systems
Workstation with dual-piston pumps
and valving connections — able to
connect up to 3 low-pressure and
3 high-pressure valves
I
Gradient mixer to ensure accurate
gradient formation
I
AVR7-3 automated injection valve with
MBB technology
I
BioLogic QuadTec™ UV/Vis detector
that enables simultaneous monitoring of
4 wavelengths for greater sensitivity
without background interference
BioLogic DuoFlow Maximizer 20 System
20 ml/min flow rate at 3,500 psi
(233 bar, 23.3 MPa)
BioLogic DuoFlow Maximizer 80 System
80 ml/min flow rate at 1,000 psi
(66 bar, 6.6 MPa)
Both systems include:
I
Standard UV detector with fixed 254
and 280 nm filters; optional filters
(214, 365, 405, and 436 nm) are
available
I
Conductivity monitor that ensures reliable
gradient formation and pump functions
I
pH monitor — high-precision calomel
electrode, fully compatible with buffers
such as Tris
I
BioFrac fraction collector that offers
flexibility with 15 different rack options to
collect microliter to liter sample volumes
I
BioLogic DuoFlow
Maximizer™ Systems
Maximizer valve system that enables
automated buffer blending, which
eliminates manual buffer titrations;
doubles flow rates for F10 and F40
pumpheads; and doubles valving
capacity (6 low-pressure and 3 highpressure valves)
I
AVR7-3 automated injection valve with
MBB technology
I
Gradient mixer with barrel extenders
to ensure accurate gradient formation
at higher flow rates
BioLogic DuoFlow Pathfinder 20 System
20 ml/min flow rate at 3,500 psi
(233 bar, 23.3 MPa)
BioLogic DuoFlow Pathfinder 80 System
80 ml/min flow rate at 1,000 psi
(66 bar, 6.6 MPa)
Both systems include:
I
BioLogic QuadTec UV/Vis detector that
enables simultaneous monitoring of 4
wavelengths for greater sensitivity
without background interference
I
Conductivity monitor that ensures reliable
gradient formation and pump functions
I
pH monitor — high-precision calomel
electrode, fully compatible with buffers
such as Tris
I
BioFrac fraction collector that offers
flexibility with 15 different rack options to
collect microliter to liter sample volumes
I
BioLogic DuoFlow
Pathfinder™ Systems
Maximizer valve system that enables
automated buffer blending, which
eliminates manual buffer titrations;
doubles flow rates for F10 and F40
pumpheads; and doubles valving
capacity (6 low-pressure and 3 highpressure valves)
I
AVR7-3 automated injection valve with
MBB technology
I
Gradient mixer with barrel extenders
to ensure accurate gradient formation
at higher flow rates
Ordering Information
Catalog #
Description
BioLogic DuoFlow Systems*
760-0037
BioLogic DuoFlow 10 System, 100/120 V, includes Dell controller
and monitor, USB Bitbus communicator, workstation, MX-1
mixer, 3-tray rack, AVR7-3 sample inject valve, fittings kit, UV
detector with 5 mm flow cell and 254/280 nm filters, conductivity
monitor, starter kit, UNO Q1 column, instructions
760-0036
BioLogic DuoFlow 10 System, 100/120 V, for Japan and Korea only
760-0038
BioLogic DuoFlow 10 System, 220/240 V
760-4037
BioLogic DuoFlow 40 System, 100/120 V
760-4036
BioLogic DuoFlow 40 System, 100/120 V, for Japan and Korea only
760-4038
BioLogic DuoFlow 40 System, 220/240 V
760-0047
BioLogic DuoFlow 10 System With BioFrac Fraction Collector,
100/120 V, includes same as 760-0037 with diverter valve and
two F1 racks
760-0046
BioLogic DuoFlow 10 System With BioFrac Fraction Collector,
100/120 V, for Japan and Korea only
760-0048
BioLogic DuoFlow 10 System With BioFrac Fraction Collector,
220/240 V
760-4047
BioLogic DuoFlow 40 System With BioFrac Fraction Collector,
100/120 V
760-4046
BioLogic DuoFlow 40 System With BioFrac Fraction Collector,
100/120 V, for Japan and Korea only
760-4048
BioLogic DuoFlow 40 System With BioFrac Fraction Collector,
220/240 V
BioLogic DuoFlow QuadTec Systems*
760-1137
BioLogic DuoFlow QuadTec 10 System, 100/120 V, includes
Dell controller and monitor, USB Bitbus communicator,
workstation, MX-1 mixer, 3-tray rack, AVR7-3 sample inject
valve, fittings kit, QuadTec UV/Vis detector with 3 mm PEEK flow
cell, instrument control module (ICM), system cables 25 and 26
(RS-232 and ICM power), conductivity monitor, starter kit, UNO
Q1 column, instructions
760-1136
BioLogic DuoFlow QuadTec 10 System, 100/120 V, for Japan
and Korea only
760-1138
BioLogic DuoFlow QuadTec 10 System, 220/240 V
760-4137
BioLogic DuoFlow QuadTec 40 System, 100/120 V
760-4136
BioLogic DuoFlow QuadTec 40 System, 100/120 V, for Japan
and Korea only
760-4138
BioLogic DuoFlow QuadTec 40 System, 220/240 V
760-1147
BioLogic DuoFlow QuadTec 10 System With BioFrac Fraction
Collector, 100/120 V, includes same as 760-1137 with diverter
valve and two F1 racks
760-1146
BioLogic DuoFlow QuadTec 10 System With BioFrac Fraction
Collector, 100/120 V, for Japan and Korea only
760-1148
BioLogic DuoFlow QuadTec 10 System With BioFrac Fraction
Collector, 220/240 V
760-4147
BioLogic DuoFlow QuadTec 40 System With BioFrac Fraction
Collector, 100/120 V
760-4146
BioLogic DuoFlow QuadTec 40 System With BioFrac Fraction
Collector, 100/120 V, for Japan and Korea only
760-4148
BioLogic DuoFlow QuadTec 40 System With BioFrac Fraction
Collector, 220/240 V
BioLogic DuoFlow Maximizer Systems*
760-2237
BioLogic DuoFlow Maximizer 20 System, 100/120 V, includes
Maximizer valve unit, Maximizer mixer, pH monitor, Dell controller
and monitor, USB Bitbus communicator, F10 workstation, MX-1
mixer, 3-tray rack, AVR7-3 sample inject valve, fittings kit, UV
detector with 5 mm flow cell and 254/280 nm filters, conductivity
monitor, starter kit, UNO Q1 column, BioFrac fraction collector,
diverter valve, two F1 racks, instructions
760-2236
BioLogic DuoFlow Maximizer 20 System, 100/120 V, for Japan
and Korea only
760-2238
BioLogic DuoFlow Maximizer 20 System, 220/240 V
760-2247
BioLogic DuoFlow Maximizer 80 System, 100/120 V
Catalog #
Description
BioLogic DuoFlow Maximizer Systems* (cont.)
760-2246
BioLogic DuoFlow Maximizer 80 System, 100/120 V, for Japan
and Korea only
760-2248
BioLogic DuoFlow Maximizer 80 System, 220/240 V
BioLogic DuoFlow Pathfinder Systems*
760-2257
BioLogic DuoFlow Pathfinder 20 System, 100/120 V, includes
Maximizer valve unit, Maximizer mixer, pH monitor, Dell controller
and monitor, USB Bitbus communicator, workstation, MX-1
mixer, 3-tray rack, AVR7-3 sample inject valve, fittings kit,
QuadTec UV/Vis detector with 3 mm PEEK flow cell, system cable
25 (RS-232), conductivity monitor, starter kit, UNO Q1 column,
BioFrac fraction collector, diverter valve, two F1 racks, instructions
760-2256
BioLogic DuoFlow Pathfinder 20 System, 100/120 V, for Japan
and Korea only
760-2258
BioLogic DuoFlow Pathfinder 20 System, 220/240 V
760-2267
BioLogic DuoFlow Pathfinder 80 System, 100/120 V
760-2266
BioLogic DuoFlow Pathfinder 80 System, 100/120 V, for Japan
and Korea only
760-2268
BioLogic DuoFlow Pathfinder 80 System, 220/240 V
Pump Kits
760-0110
F10 Pump Kit, converts F40 workstation to F10 pumps to
enable flow rates as low as 0.01 ml/min; includes 2 fully
assembled pumpheads, 4 piston assemblies, F10 tubing kit,
tools, instructions
760-0180
F40 Pump Kit, expands pumping capabilities to 40 ml/min;
includes 2 fully assembled pumpheads with seals and check
valves installed, 4 piston assemblies, mixer barrel extender,
2 mm UV flow cell, F40 tubing kit, tools, instructions
BioLogic Maximizer™ Valve System
760-2200
BioLogic Maximizer Kit, 100/120 V, for US, Japan, Korea;
includes Maximizer base unit, pH monitor, Maximizer mixer,
starter kit, tubing kit, system cable 30, US power cord
760-2204
BioLogic Maximizer Kit, 220/240 V, same as 760-2200
without US power cord
Detectors and Accessories
750-0200
BioLogic DuoFlow Detector Kit, includes UV optics module and
conductivity monitor, 5 mm analytical flow cell
760-1300
BioLogic QuadTec Detector Kit, includes QuadTec detector with
3 mm PEEK flow cell, instrument control module (ICM), system
cables 25, 26, and 17 (QuadTec RS-232, ICM power, and bus
communication), US power cord, instructions, 40 psi
backpressure regulator
760-2040
BioLogic DuoFlow pH Monitor, includes SIM module, pH
electrode, flow cell, and tubing
750-0502
Signal Import Module, includes 4' communication cable
(system cable 17), required for external detectors
760-2034
Universal AC/DC Inline Adaptor for USB Bitbus Device, required
when connecting pH monitor or other external detector through
SIM module on BioLogic DuoFlow systems
BioLogic DuoFlow Valves
760-0406
AVR7-3 Automated Sample Injection Valve, 7-port, 3-position
high-pressure valve, 3,500 psi (233 bar) limit
760-0408
AVR9-8 Stream-Select Valve, 9-port, 8-position high-pressure
valve, 3,500 psi (233 bar) limit
760-0410
SVT3-2 Diverter Valve, 3-port, 2-position solenoid valve,
30 psi (2 bar) limit
750-0415
SV5-4 Select Valve, 5-port, 4-position solenoid valve,
30 psi (2 bar) limit
* The 10 and 20 systems include F10 workstation; the 40 and 80 systems
include F40 workstation. 100/120 V systems for Japan and Korea and
220/240 V systems do not include Dell monitor.
Dell is a trademark of Dell Laboratories. MBB is a trademark of Rheodyne, LLC.
MBB technology is covered by US patent 4,506,558, issued to Rheodyne, LLC.
PEEK is a trademark of Victrex PLC.
Bio-Rad
Laboratories, Inc.
Web site www.bio-rad.com USA 800 4BIORAD Australia 02 9914 2800 Austria 01 877 89 01 Belgium 09 385 55 11 Brazil 55 21 3237 9400
Canada 905 712 2771 China 86 21 6426 0808 Czech Republic 420 241 430 532 Denmark 44 52 10 00 Finland 09 804 22 00 France 01 47 95 69 65
Germany 089 318 84 0 Greece 30 210 777 4396 Hong Kong 852 2789 3300 Hungary 36 1 455 8800 India 91 124 4029300/5013478 Israel 03 963 6050
Italy 39 02 216091 Japan 03 5811 6270 Korea 82 2 3473 4460 Mexico 55 5200 05 20 The Netherlands 0318 540666 New Zealand 64 9415 2280
Norway 23 38 41 30 Poland 48 22 331 99 99 Portugal 351 21 472 7700 Russia 7 095 721 14 04 Singapore 65 6415 3188 South Africa 27 0861 246 723
Spain 34 91 590 5200 Sweden 08 555 12700 Switzerland 061 717 95 55 Taiwan 886 2 2578 7189/2578 7241 United Kingdom 020 8328 2000
Life Science
Group
Bulletin 5369
US/EG
Rev A
05-0807
0506
Sig 1205
Download PDF