DAVID KOPF INSTRUMENTS
Precision Designs for Research
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DAVID KOPF INSTRUMENTS
STEREOTAXIC INSTRUMENTS
SPINAL UNITS
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ANIMAL ADAPTORS
MICROPOSITIONERS
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DRILLS
PIPETTE PULLERS
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DAVID KOPF INSTRUMENTS
Ordering Information
Please contact KOPF for all of your
laboratory research requirements. Our
primary goal is to provide our customers
with uncompromised quality, continuous
technical support, as well as dependable
customer service.
TOLL FREE
1-877-352-3275
TELEPHONE
1-818-352-3274
FAX
1-818-352-3139
David Kopf Instruments has compiled an easy to
read condensed catalog to provide our customers with an
outline of the various products we manufacture.
We encourage customers to contact our customer service
for assistance in assembling a stereotaxic instrumentation
package. Our knowledgeable staff will work with you to
identify which stereotaxic frame set-up, animal adaptor(s)
and surgical tools are needed to fulfill your research requirements.
For complete product information and specifications please
visit www.kopfinstruments.com
How To Order –
All orders should be addressed to
our Tujunga office. Orders may be placed by telephone,
fax or email. Formal purchase order and/or credit card is
required to process order. Products for sale, delivery or use
outside the United States must be purchased through an
authorized David Kopf Instruments representative or direct
through our Tujunga office.
Pricing –
Prices are per the current price list and are
subject to change without notice. Special items and low
volume items will be quoted upon request.
Minimum Order – $50 (Domestic) $75 (Foreign)
E-MAIL
sales@kopfinstruments.net
WEB SITE
www.kopfinstruments.com
MAIL
7324 Elmo Street
Tujunga, CA 91042
Terms of Sale – F.O.B. Tujunga, California USA
Terms of Payment – Net to established institutions.
We reserve the right to hold orders pending payment of
overdue accounts or to require payment in advance.
Form of Payment –
U.S. currency only. Check,
Wire Transfer, Visa, MasterCard and American Express
accepted.
Taxes –
Quotations and invoices do not include local
taxes or tariffs. David Kopf Instruments will not be responsible for their collection of payment except for non-exempt
California sales.
Service –
David Kopf Instruments products are
available on a worldwide basis through
selected sales and service representatives. Contact our main office for your
authorized factory representative.
Complete service facilities are located at our
factory in Tujunga, California. Repairs and modifications
are available. Some items could be rendered obsolete by
design changes. In this instance, replacement items can
generally be substituted. All returned items must include
proper documentation, including name, telephone number
and address.
David Kopf Instruments • www.kopfinstruments.com
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DAVID KOPF INSTRUMENTS
Contents
Ordering Information.................................................................................................. inside cover
Table of Contents.......................................................................................................................... 1
Stereotaxic Alignment System..................................................................................................... 4
Stereotaxic Alignment Tools........................................................................................................ 5
Small Animal Stereotaxic Instruments........................................................................................ 6
Small Animal Stereotaxic Frame Upgrade Options.................................................................... 9
Small Animal Stereotaxic Instruments Motorized.................................................................... 10
Large Animal Stereotaxic Instruments...................................................................................... 12
Stereotaxic Manipulators for large animal frames................................................................... 14
MRI Stereotaxic Frames for small and large animals.............................................................. 15
Animal Adaptors.......................................................................................................................... 16
Ear Bars........................................................................................................................................ 19
Anesthesia Masks....................................................................................................................... 19
Stereotaxic Holders..................................................................................................................... 20
Drills............................................................................................................................................. 21
Microinjection Unit...................................................................................................................... 22
Temperature Controller............................................................................................................... 22
Spinal Units.................................................................................................................................. 23
Pipette Pullers............................................................................................................................. 24
Micropositioners.......................................................................................................................... 25
Warranty & Disclaimer................................................................................................................ 26
For complete Kopf product line including equipment specifications please refer to
www.kopfinstruments.com
Toll Free: 1-877-352-3275 • Fax: 1-818-352-3139 • E-mail: sales@kopfinstruments.net
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DAVID KOPF INSTRUMENTS
Complete line of Kopf instrumentation is listed below. Product details and
specifications are available at www.kopfinstruments.com.
Stereotaxic Alignment System
Model 1900 Stereotaxic Alignment Instrument
Model 1901 Adjustable Stage Platform
Model 1905 Alignment Indicator
Model 1910 Dial Test Indicator
Model 1911 Stereotaxic Drilling Unit
Model 1915 Centering Scope
Model 1923-B Mouse Gas Anesthesia Head Holder
Model 1924-B Neonatal Rat Gas Anesthesia Head Holder
Model 1925 15 Degree Angle Adapter
Model 1929-B Rat Gas Anesthesia Head Holder
Model 1940 Micro Manipulator Digital Display
Model 1950 Universal Off-Plane Adapter
Model 1966 Cannula Holder
Model 1970 Electrode Holder
Model 1971 Syringe Pump Adapter
Model 1972 Syringe Holder
Model 1973 Dual / Model 1974 Single Cannula Insertion Tool
Model 1975 Glass Pipette Holder
Small Animal Stereotaxic Instruments
Model 900 Small Animal Stereotaxic
Model 900LS Lazy Susan Small Animal Stereotaxic
Model 900SD Motorized Small Animal Stereotaxic
Model 902 Dual Small Animal Stereotaxic
Model 930 Small Animal Stereotaxic Frame Assembly
Model 932 Dual Small Animal Stereotaxic Frame Assembly
Model 940 Digital Small Animal Stereotaxic
Model 942 Dual Digital Small Animal Stereotaxic
Model 962 Dual Ultra Precise Small Animal Stereotaxic
Model 963 Ultra Precise Small Animal Stereotaxic
Model 963SD Motorized Ultra Precise Small Animal Stereotaxic
Large Animal Stereotaxic Instruments
Model 1404 Heavy-Duty Research Model Stereotaxic
Model 1430 Stereotaxic Frame Assembly
Model 1504 Heavy-Duty Research Model Stereotaxic
Model 1530 Stereotaxic Frame Assembly
Model 1730 Intracellular Frame Assembly
MRI Stereotaxic Instruments for Small & Large Animals
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Model 324 Rat and Model 325 Mouse MRI Head Holder
Model 900M Small Animal MRI Stereotaxic
Model 923M Mouse Gas Anesthesia Head Holder
Model 1430M Large Animal MRI Stereotaxic
Model 1530M Large Animal MRI Stereotaxic
Model 1630M Large Animal MRI Stereotaxic
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DAVID KOPF INSTRUMENTS
Animal Adaptors
Bird
Cat
Dog
Ferret, Mink
Guinea Pig
Monkey
Mouse
Prairie Vole
Rabbit
Rat
Siberian Hamster
Squirrel Monkey
Ear Bars
Optical and Semi Chronic Head Holding Devices
35 mm Offset Adaptors & Raised Eye Bars, Inverted Palate Clamp
Special Order Animal Adaptors
Stereotaxic Accessories
Adjustable Stage Platform
Alignment Tools
Anesthesia Masks
A/P Slide Attachment
Base Plates
Drills, Drill Press
Ear Bar Adaptor
Electrode Angle Calibrator, Calibrated A/P Zeroing Bar & Carrier Stand
Electrode Holders & Clamping Devices
Electrode & Micro Manipulators
Microinjection Unit
Removable Zero Point
Temperature Control System
45 Degree Adaptor Slide
Spinal Units
Model 980 Small Animal Spinal Unit
Model 1780 Large Animal Spinal Unit
Pipette Pullers
Model 720 Needle Pipette Puller
Model 730 Needle Pipette Puller
Model 750 Programmable Needle Pipette Puller
Micropositioners
Model 608 X/Y Chronic Adapter
Model 640 Manual Hydraulic Micropositioner
Model 2650 Hydraulic Micropositioner
Model 2660 Direct Drive High Speed Micropositioner
Model 2662 Direct Drive High Speed Micropositioner
Model 2670 Hydraulic Micropositioner
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Stereotaxic Alignment System
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DAVID KOPF INSTRUMENTS
Offering a new level of precision and accuracy,
Model 1940 Micro Manipulator provides 1 micron
resolution linear glass scales with digital display
readout, proving this instrument to be the most advanced manual manipulator available today. Our
quick change tool holder allows you to attach any
stereotaxic alignment tool and maintain an exact
common vertical centerline position tool-to-tool.
This valuable feature will assist in reducing surgical
time, increase hit rates and greatly reduce potential
time consuming errors, which provides a repeatable
platform for your research.
Model 1900 Standard Accessories
(supplied with Model 1900)
Model 1900-B Head Holder Assembly
Model 1900-C Base Plate and Slide Assembly
Model 1900 Stereotaxic Alignment System
Model 1923-B Mouse Gas Anesthesia Head Holder
provides the ability to manipulate and refine the
position of the head in 3 dimensional space, prior to
exploring inside the head and brain.
Model 1922 Non-Rupture 60° Tip Mouse Ear Bars
The stereotaxic alignment system was originally
designed and developed by Joseph Saracione,
Cartesian Research Inc. Our patented design offers the maximum stereotaxic adjustment available
for positioning the animal’s head; dorsal/ventral,
dorsal tilt, coronal tilt, anterior/posterior and midline
alignment (nose left/nose right) adjustments. This
complete unit is mounted to 18˝x 18˝x 1˝ precision
ground aluminum base plate. The overall mass and
rigidity of this instrument provides ultimate stability.
Recommended Accessories
The instrument is fitted with two large dovetail rails
for mounting manipulators and additional accessories. The sagittal alignment plate is designed for use
with and includes a centering height gauge. This
gauge represents the position of the bregma landmark on the top of the skull of the research subject
when mounted to the sagittal alignment plate.
Model 1911 Stereotaxic Drilling Unit
Model 1923-B Gas Anesthesia Head Holder and
Model 1922 Non-Rupture 60° Tip Ear Bars for mice
are included. Custom palate bar design will insure
absolute stability of the head. We have incorporated
a custom nose clamping device that can be utilized
for delivering gas anesthesia via connection to the
inlet/outlet port located on the anesthesia mask.
Model 1900-51 Centering Height Gauge
Model 1905 Alignment Indicator provides dimensional feedback required for leveling the head.
Model 1910 Dial Test Indicator is necessary for
calibrating the stereotaxic manipulator. Indicator
will provide dimensional feedback required to verify
manipulator alignment is perpendicular and square
relative to the precision ground stereotaxic base
plate.
Model 1915 Centering Scope 40X magnification is
used to assist with positioning the manipulator accurately over the centering height gauge (zero point
of reference). This zero point is used to zero out
the manipulator readout display and for setting the
tool height for all tools to be used in the surgical
procedure.
Model 1940 Micro Manipulator with Digital Display
1 micron resolution, 3-axis
***Additional tools may be necessary based on
surgical requirements. Custom tools available and
quoted upon request.
Patent number 6,258,103
Patent number 6,716,220
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David Kopf Instruments • www.kopfinstruments.com
Stereotaxic Alignment Tools
Model 1905
Alignment Tool
Model 1973
Dual Cannula Holder
(26 guage)
Model 1910
Dial Test
Indicator
Model 1974
Cannula Holder
(26 guage)
Model 1911
Drilling Unit
Model 1966
Cannula Holder
Alzet/Plastic One
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DAVID KOPF INSTRUMENTS
Model 1915
Centering
Scope 40x
Model 1972
Syringe Holder
Model 1975
Pipette Holder
(1 mm, 1.5 mm
or 2 mm)
Model 1970
Electrode Holder
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DAVID KOPF INSTRUMENTS
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Small Animal Stereotaxic Instruments
Model 900 Single Manipulator 100 micron
Model 900LS Single Manipulator 100 micron
Model 963 Single Manipulator 10 micron
Model 940 Single Manipulator 10 micron
David Kopf Instruments • www.kopfinstruments.com
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DAVID KOPF INSTRUMENTS
Kopf Small Animal Stereotaxic Instrument
originally designed by David Kopf Instruments in
1963, is a versatile, easy-to-use instrument that
facilitates proper alignment of small animals for the
stereotaxic placement of electrodes, micropipettes,
cannula and other devices.
The precise manner in which the instrument is built
and assembled assures that the researcher will be
able to make accurate and repeatible placements.
Precise alignment of the slides assures smooth
movements resulting in correct use of the atlases.
Kopf Small Animal Stereotaxic Frames
These instruments consist of a rugged “U” frame
assembly to which is affixed a specified Kopf threedimensional manipulator.
Manipulator X,Y,Z adjustment – Metric scale
80mm travel, 100 micron, 10 micron and 10 micron
digital display, single or dual options available.
Angle adjustment – Fully universal joint calibrated on two planes for access from any angle.
Vertical alignment pin can be removed for angled
settings from 0°– 90° either side of vertical, 2° increments. New design includes a precision t-bolt
locking mechanism to insure angles are held firm
and rigid in place to provide positive angle presentations. (Photos do not display t-bolt design)
Rotation adjustment – Manipulator swivel base
can be rotated up to 360°. Manipulator X/Z axis can
be repositioned at 90° increments.
The stereotaxic frame is mounted to a 17˝L x 10˝W
base plate and is elevated to bring ear bar height to
53 mm. Ear bar slots on the “U” frame have 0.1 mm
verniers for ease in centering an animal. Ear bar
zero to posterior end of base plate is 8.763˝.
Model 1770 Electrode Holder with corner clamp
and Model 920 Rat Adaptor are standard accessories included. Standard accessories that are not
required can be omitted.
Rat Adaptor features:
Dorsal/Ventral adjustment dial – Calibrated in 100 micron increments, 1 mm per revolution Dorsal/Ventral adjustment – 30 mm Dorsal – 10 mm above ear bar zero Ventral – 20 mm below ear bar zero Adaptor Plate A/P adjustment – 44 mm Ear Bars – Model 957 18° Tip Rat Ear Bars (6.3 mm square with 35 mm of calibration)
Kopf Small Animal Stereotaxic Frames
with standard accessories
100 micron resolution Model 900 Single/902 Dual Small Animal Frame Stereotaxic “U” Frame Assembly Model 960 Electrode Manipulator (0.1 mm res.)
(x2 for Model 902) Model 1770 Electrode Holder with corner clamp
Model 920 Rat Adaptor including one set of
Model 957 18° Tip Rat Ear Bars Model 900-C Base Plate (17˝L x 10˝W)
10 micron resolution Model 963 Single/962 Dual Ultra Precise
Small Animal Frame Stereotaxic “U” Frame Assembly Model 961 Micro Manipulator (0.01 mm res.) (x2 for Model 962) Model 1770 Electrode Holder with corner clamp
Model 920 Rat Adaptor including one set of
Model 957 18° Tip Rat Ear Bars Model 900-C Base Plate (17˝L x 10˝W)
10 micron resolution digital Model 940 Single/942 Dual Small Animal Frame
with Digital Display Console Stereotaxic “U” Frame Assembly Model 940-B Linear Scale Assembly with Digital
Display Readout Console (0.01 mm resolution) (Model 942-B Dual Display for Model 942)
Model 960 Electrode Manipulator (0.1 mm res.)
(x2 for Model 942) Model 1770 Electrode Holder with corner clamp
Model 920 Rat Adaptor including one set of
Model 957 18° Tip Rat Ear Bars Model 900-C Base Plate (17˝L x 10˝W)
Model 930 Single/932 Dual Small Animal Frame
Model 930-B Stereotaxic Frame Assembly
(one AP Bar) with Base Plate (17˝L x 10˝W)
(Model 932-B Dual AP Bars)
Model 920 Rat Adaptor including one set of
Model 957 18° Tip Rat Ear Bars
Manipulators for use with Model 930 and 932 are
sold separate (see page 12).
Toll Free: 1-877-352-3275 • Fax: 1-818-352-3139 • E-mail: sales@kopfinstruments.net
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DAVID KOPF INSTRUMENTS
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Small Animal Stereotaxic Instruments
Model 902 Dual Manipulator 100 micron
Model 962 Dual Manipulator 10 micron
Model 942 Dual Manipulator 10 micron
Model 930 Frame with
Model 1460 Electrode Manipulator
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DAVID KOPF INSTRUMENTS
Kopf provides a variety of frame
upgrades options
Add a second manipulator
Model 940-B Digital Display upgrade is designed for
use on Model 900 Small Animal Stereotaxic frame.
Model 942-B Digital Display upgrade is designed
for use on Model 902 Dual Small Animal Frame.
The linear scales/encoders along with the easy-toread digital display readout console will upgrade a
100 micron resolution set-up to an improved 10 micron resolution. The digital display control features
allow “zero” reset at any position.
100 micron resolution Model 960-RIGHT Electrode Manipulator – Metric scale 80 mm travel, calibrated 0.1 mm
vernier scale (3.00 mm advance per revolution)
Kopf provides repair and calibration
services
Upgrading an existing Small Animal Stereotaxic
Instrument is an affordable way to increase the accuracy of your stereotaxic set-up. Adding a second
manipulator enables the use of additional tools during a surgerical procedure.
10 micron resolution Model 961-RIGHT Micro Manipulator – Metric scale 80 mm travel,
calibrated dial – 0.01 mm resolution
(1.0 mm advance per revolution)
Add digital display
10 micron resolution digital display Model 940-B Digital Display upgrade – Linear scales 10 micron resolution encoders with
digital display console.
Model 900 Single Manipulator 100 micron
Due to extensive usage or in some cases negligent
care Kopf offers repairs/reconditioning/calibration
services. This service will insure that alignment and
calibration of instruments are within our quality specifications. Any mechanical instrument regardless of
how well it is made will require calibration and or repair. This service is critical to insuring the continued
accuracy of the equipment and will prolong the life
of your Kopf instrumentation for decades.
Model 940-B upgrade mounted to Model 900
= Model 940 Digital Small Animal Stereotaxic
*All frame upgrades require factory installation and calibration.
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DAVID KOPF INSTRUMENTS
Small Animal Stereotaxic Instruments
Model 900SD Neurostar Motorized Small Animal Stereotaxic Instrument
Model 963SD Neurostar Ultra Precise Motorized Small Animal Stereotaxic Instrument
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DAVID KOPF INSTRUMENTS
David Kopf Instruments is pleased to introduce our
collaboration with Neurostar, Germany, the inventor
of the Motorized Stereotaxic (www.neurostar.de).
We now offer Kopf stereotaxic instruments and manipulators with robotic features including state-of-art
software.
Features
Kopf’s area of expertise will continue to focus on
the design, accuracy and mechanical functioning
of the stereotaxic frame, mechanical manipulator
and head holding devices. Kopf frames will be the
mechanical foundation for the Neurostar Motorized
Stereotaxic. Robotic features and software are integrated by Neurostar. The finished product will be
supported by Neurostar.
xx Avoids Human Errors
Using the Motorized Stereotaxic you can focus on
the experiment without having to manipulate the stereotaxic by hand. Neurostar’s software allows you
to control the motorized positioning of the probe in
all three orthogonal axes by using the keyboard arrow keys, by clicking on the screen with the mouse
or by using a joystick.
xx Ultra Precise
Neurostar’s Atlas Integration and Intuitive Movement Control enable ultra precise and reproducible
stereotaxic microinjections, probe positioning and
highly accurate automated drilling, craniotomy and
brain windowing. Automated atlas adjustment by
smart software algorithms compensates for human
errors, interindividual variations and alignment inaccuracies.
Neurostar’s software facilitates experiment planning by atlas browsing, target definition, storage
and retrieval. The optional usage of Robot AddOns such as Robot Drill, Robot Microinjection and
Smart Bregma Finder saves time, increases experiment accuracy and reproducibility, enabling highthroughput stereotaxic procedures.
xx Computer Control
xx Atlas Integration
xx Head Tilt Correction
xx Experiment Planning
xx Define/Store Targets
xx Intuitive Navigation
xx Angle Adjustments
xx Bregma Setting
xx Time Saving
xx High Throughput
Stereotaxic Frame Includes:
Stereotaxic “U” Frame Assembly
Model 1770 Electrode Holder with corner clamp
Model 920 Rat Adaptor including one set of
Model 957 18° Tip Rat Ear Bars Model 900-C Base Plate (17˝L x 10˝W)
Any standard accessories that are not required
can be omitted and the appropriate accessories
quoted.
Kopf offers a wide range of animal adaptor, ear
bars and stereotaxic holders.
Existing Kopf frames can be upgraded to incorporate any of these motorized options.
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DAVID KOPF INSTRUMENTS
Large Animal Stereotaxic Instruments
Model 1404 Frame
with Model 1460 Manipulators
Model 1504 Frame
with Model 1460 Manipulators
Model 1730 Intracellular Frame
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DAVID KOPF INSTRUMENTS
Model 1404 Stereotaxic Instrument consists of
Model 1430 Frame Assembly with four Model 1460
Electrode Manipulators. Manipulator resolution is
100 microns (0.1 mm) all axis. Frame is equipped
for use with cat or monkey but can be easily adapted for other animals. Frame and manipulators can
be quoted separately.
A/P Bar(s) – 18.70 mm square
A/P Bar length – 30.50 cm
A/P Bar calibration – 100 mm each side of zero
(ear bar centerline)
Model 1404 Standard Accessories
(supplied with Model 1404)
Model 1430-B Stereotaxic Frame Assembly
with one set of ear bar locators
Model 1210 Table Mount Base Plate 4¾˝ x 3½˝
Model 1225 Universal Swivel Stand
Model 1245 Cat / Monkey Adaptor including
Model 851 Standard Solid Ear Bars
Model 1460 Electrode Manipulator (Qty. 4)
Model 1770 Standard Electrode Holder
Frame Bar centerline distance – 17.78 cm
A/P zero to posterior end of bar – 12.08 cm
Ear Bar Locator position – A/P zero
Model 1504 Stereotaxic Instrument consists of
Model 1530 Frame Assembly with four Model 1460
Electrode Manipulators. Manipulator resolution is
100 microns (0.1 mm) all axis. Frame is equipped
for use with dog or large monkey. Frame and manipulators can be quoted separately.
A/P Bar(s) – 18.70 mm square
A/P Bar length – 37.47 cm
A/P Bar calibration – 100 mm each side of zero
(ear bar centerline)
Frame Bar centerline distance – 17.78 cm
A/P zero to posterior end of bar – 12.08 cm
Ear Bar Locator position – A/P zero and 5 cm
anterior
Model 1730 Intracellular Frame Assembly
is designed primarily for intracellular recording and
stimulation where high inertia, precision and clear
access to the head during surgery are paramount.
Frame is equipped for use with cat or monkey but
can be easily adapted for other animals. Designed
for use with 1760 and 1460-LB series manipulators
(shown on page 12).
A/P Bar(s) – 21.65 mm square
A/P Bar length – 30.50 cm
A/P Bar calibration – 100 mm each side of zero
(ear bar centerline)
Frame Bar centerline distance – 17.78 cm
A/P zero to posterior end of bar –12.08 cm
Ear Bar Locator position – A/P zero
Model 1430 Stereotaxic
Frame Assembly
Model 1504 Standard Accessories
(supplied with Model 1504)
Model 1530-B Stereotaxic Frame Assembly
with one set of double ear bar locators Model 1210 Table Mount Base Plate 4¾˝ x 3½˝ Model 1225 Universal Swivel Stand
Model 1535 Dog / Monkey Adaptor including
Model 851 Standard Solid Ear Bars Model 1460 Electrode Manipulator (Qty. 4)
Model 1770 Standard Electrode Holder
Model 1730 Standard Accessories
(supplied with Model 1730)
Model 1730-B Intracellular Frame Assembly
with one set of ear bar locators
Model 1711 Intracellular Base Plate
Dimensions: 22˝L x 12˝W x 1½˝H
Model 1725 Universal Clamp and Stand Post
Model 1735 Vertical Outboard Posts and Tie Bar
Model 1745 Cat / Monkey Adaptor including
Model 1751 Standard Solid Ear Bars
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Manipulators for Large Animal Frames
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DAVID KOPF INSTRUMENTS
Kopf Electrode Manipulators
100 micron resolution
Model 1460, 1460-61, 1460-LB, 1460-61-LB
Manipulator X, Z adjustment – Metric scale 80 mm travel, calibrated 0.1 mm
vernier scale (3.00 mm advance per revolution)
Manipulator Y adjustment –
Model 1460 – Manual adjustment 100 mm each
side of zero (A/P bar) 0.1 mm vernier scale
Manipulator Y adjustment –
Model 1460-61 – Metric scale 25 mm travel, calibrated dial – 0.01 mm resolution
(1.0 mm advance per revolution)
1460-61
1460
Angle adjustment – Fully universal joint calibrated on two planes for access from any angle. Vertical alignment pin can be removed
for angled settings from 0° – 90° either side of
vertical, 2° increments. Manipulator swivel design includes a precision t-bolt locking mechanism to insure angles are held firm and rigid in
place to provide positive angle presentations. (Photos do not display t-bolt design)
Rotation adjustment – Manipulator swivel base
can be rotated up to 360°. Manipulator X/Z axis can
be repositioned at 90° increments.
Kopf Micro Manipulators
10 micron resolution
Model 1760, 1760-61, 1760-SB, 1760-61-SB
Manipulator X, Z adjustment – Metric scale 80 mm travel,
calibrated dial – 0.01 mm resolution
(1.0 mm of travel per revolution)
Manipulator Y adjustment – Model 1760 – Manual adjustment 100 mm each
side of zero (A/P bar) 0.1 mm vernier scale
Manipulator Y adjustment – Model 1760-61 – Metric scale 25 mm travel,
calibrated dial – 0.01 mm resolution (1.0 mm advance per revolution)
Angle and Rotation adjustment – Same specifications as noted for 1400 series
manipulators above.
1760-61
1760
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Models 1460, 1460-61, 1760-SB, 1760-61-SB
compatible for use with 18.70 mm AP bar.
Models 1760, 1760-61, 1460-LB, 1460-61-LB
compatible for use with 21.65 mm AP bar.
David Kopf Instruments • www.kopfinstruments.com
MRI STEREOTAXIC INSTRUMENTS
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DAVID KOPF INSTRUMENTS
Model 900M Small Animal MRI Stereotaxic Instrument is designed to successfully stabilize small
animals for stereotaxic surgery. Model 900M-B MRI
Head Holder Assembly with Model 920M Rat Adaptor with ear bars provides easy access and removal
from the stereotaxic base for insertion into MRI device. The removable MRI head holder is designed
to fit into a MRI device 12 cm diameter (or larger).
A/P Bar – 18.70 mm square
A/P Bar length – 25.40 cm
A/P Bar calibration – 100 mm each side of zero
(ear bar centerline)
A/P zero to posterior end of bar – 12.70 cm
Ear Bar Locator position – A/P zero
Model 900M-B MRI Head Holder Assembly
Dimensions:
16˝ (40.64 cm) length
3.964˝ (10.07 cm) width
3.430˝ (8.71 cm) height
Material:
ULTEM-1000,
Nylon 6-6, Delrin
Model 1430M MRI Stereotaxic Instrument is
designed to successfully stabilize a cat or monkey
for stereotaxic surgery. Unit can be repositioned into
a MRI device without generating electromagnetic
interference. Model 1245M Cat / Monkey Adaptor
with ear bars are included.
A/P Bar(s) – 18.70 mm square
A/P Bar length – 30.50 cm
A/P Bar calibration – 100 mm each side of zero
(ear bar centerline)
Frame Bar centerline distance – 17.78 cm
A/P zero to posterior end of bar – 12.08 cm
Ear Bar Locator position – A/P zero
Dimensions:
16.500˝ (42 cm) length
7.937˝ (20.16 cm) width
8.857˝ (22.5 cm) height
Weight: 7lbs. 12 oz
Material:
ULTEM-1000,
Nylon 6-6, Delrin
Model 1530M MRI for Dog / Large Monkey
Frame A/P Bar Length – 37.46 cm
Frame Bar centerline distance – 17.78 cm
Model 1630M MRI Special (larger frame width)
Frame A/P Bar Length – 37.46 cm
Frame Bar centerline distance – 22.86 cm
Toll Free: 1-877-352-3275 • Fax: 1-818-352-3139 • E-mail: sales@kopfinstruments.net
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Animal Adaptors
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DAVID KOPF INSTRUMENTS
Rat
Mouse
Model 921-E Low Profile
Model 920-E Low Profile
Mouse
Rat
Model 920 Traditional
Model 926 Traditional
Mouse
Rat
Model 929-B
Gas Anesthesia
Model 923-B
Gas Anesthesia
Neonatal Rat
Neonatal Mouse
Model 933-B
Gas Anesthesia
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Model 973-B
Gas Anesthesia
David Kopf Instruments • www.kopfinstruments.com
Animal Adaptors
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DAVID KOPF INSTRUMENTS
Neonatal Rat
Model 970
Guinea Pig
Model 916
Bird
Small Bird
Model 1215
Model 914
Squirrel Monkey
Pigeon
Model 1218
Model 1248
Cat / Monkey
Model 1245
Dog / Monkey
Model 1535
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Animal Adaptors
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DAVID KOPF INSTRUMENTS
Rabbit
Ferrett
Model 1240
Model 927
Rotational Rat
Model 924
Piglet
Model 1541
Prairie Vole
Neonatal Lamb
Model 931
Model 1247
Cat / Monkey
Model 865
35mm Offset Ear Bars & Riser Block
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Cat / Monkey
Model 866
35mm Offset Ear Bars & Riser Block
David Kopf Instruments • www.kopfinstruments.com
Ear Bars
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DAVID KOPF INSTRUMENTS
Set # Model #
Name
Description
1
821
921
1721
Non-Rupture
(Mouse, Neonatal Rat)
Zygoma ear cups
(serrated and soft tissue)
2
822
922
1722
Non-Rupture
(Mouse, Siberian Hamster)
60° Non-Rupture tip
3
851
951
1751
Standard Solid
(Cat / Monkey)
20° tapered tip with
a 1.5 mm radius
4
852
952
1752
Non-Rupture
(Cat / Monkey)
20° tapered tip to a 4.8 mm
shoulder with a 3 mm dia. by
2 mm long protrusion
5
853
953
1753
Hollow
(Cat / Monkey)
4 mm hole through for
auditory stimulation
6
855
955
1755
Non-Rupture
(Bird, Guinea Pig, Prairie Vole,
Rat, Squirrel Monkey)
45° Non-Rupture tip with
a 0.8 mm radius
Hollow Ear Bars are also available
7
856
956
1756
(Pigeon)
3 mm dia. by 6 mm long tip
with a full radius on end
8
857
957
1757
(Rat)
Tip Shape Shown
Hollow Ear Bars are also available
18° tip with 0.8 mm radius
Hollow Ear Bars are also available
800 series ear bars have 50 mm calibration markings, 6.3 mm square for use on 1430 / 1530 frames.
900 series ear bars have 35 mm calibration markings, 6.3 mm square for use on 900 series frames.
1700 series ear bars have 50 mm calibration markings, 9.4 mm square for use on 1730 frame.
Anesthesia Mask
Model 906 Rat Anesthesia Mask compatible
with Model 920, 1220, 1520 & 1720 Rat Adaptors.
Design includes a dorsal adjustment screw which
can be used to apply pressure down onto the nose
for securing upper jaw onto adaptor tooth bar. A
rubber seal insert lines the internal cavity of the rat
anesthesia mask. Inlet and outlet ports are 5/16˝
outside diameter.
Model 907 Mouse Anesthesia Mask compat-
ible with Model 921-E, 926, 1226, 1526 & 1726
Mouse Adaptors. Inlet and outlet ports are 5/16˝
outside diameter.
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Stereotaxic Holders
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DAVID KOPF INSTRUMENTS
Electrode, Glass Pipette, Hypodermic Tubing
1770
1771
Model 1769 90° holds electrodes
from 0.4 mm to 1.3 mm diameter.
Model 1770 with Corner Clamp
holds electrodes from 0.4 mm to
1.3 mm diameter.
Model 1771 with Straight Clamp
holds electrodes from 0.4 mm to
3.8 mm diameter.
1773
1774
Model 1771-A-Mod includes a
clamp pad adhered to the inside
of clamp for holding glass pipettes
.092 mm to 2.325 mm.
Model 1773 with Removable
Open Side Clamp holds electrodes from 0.4 mm to 3.6 mm
diameter.
1769
Model 1774 Wedge Holder with
Removable Flag has a tapered
profile for positioning numerous
electrodes close together.
Cannula, Syringe
1766-AP
1772-F
1776-P2
Model 1766-AP holds Alzet and
Plastic One cannula 3.4 mm to
3.5 mm diameter pedestal.
Model 1772 Universal holds diameters from 2.8 mm to 11 mm
diameter. Model 1772-F includes
needle support foot designed to
hold Hamilton syringes.
Model 1776 Custom drilled to
hold specific diameter. Hole sizes
available from 1.5 mm to 6 mm.
(Special Order)
1776-P1
1779
Model 1776-P2 Dual Adjustable
Cannula holds (2) Alzet and Plastic One cannula 3.4 mm to 3.5 mm
diameter pedestal.
Model 1776-P1 holds Alzet and
Plastic One cannula 3.4 mm to
3.5 mm diameter pedestal.
Model 1779 Cannula holds a variety of guide cannula manufactured
by CMA Microdialysis.
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David Kopf Instruments • www.kopfinstruments.com
Stereotaxic Drills
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DAVID KOPF INSTRUMENTS
Model 1474 High Speed Stereotaxic Drill can
be run at a variable speed with dial or foot pedal
control. Control speed range is 0–45,000 rpm. Both
the micro motor and foot pedal control have forward
and reverse operation. Steady constant speed can
be achieved with proper flip of the switch from foot
to manual control.
Additional design features includes a quick change
rotary chuck handpiece with DC motor housed
within. This handpiece is distinguished from flexible
shaft machines by higher speed performance and
added flexibility. Standard collet 1/8˝. The handpiece
is vibration-free, quiet running and lightweight.
Model 1474 Handpiece
Collet 1/8˝
Size: 6˝ overall length
5/8˝ grip diameter
1˝ motor diameter
1.75 amps (110V)
.75 amps (220V)
Weight: 7.5 ounces
Model 1464 Handpiece Holder included.
(Drill bits sold separately)
Models 1470 and 1471 Stereotaxic Drills
include the Foredom hanging motor with foot
pedal. Speed control range from 0–14,000 rpm,
110–130 volts AC/DC.
Model 1470 Handpiece
Collet 3/32˝
Size: 3/4˝ diameter
Length: 10¾˝
Weight: 5 ounces (handpiece only)
Model 1466 Handpiece Holder included.
(Drill bits for 3/32” not provided)
Model 1471 Handpiece
Collet Jacobs chuck 0 to 3.9 mm diameter
Size: 1˝ diameter
Length: 5¼˝
Weight: 6 ounces (handpiece only)
Model 1469 Handpiece Holder included.
(Drill bits sold separately)
1470
1471
Toll Free: 1-877-352-3275 • Fax: 1-818-352-3139 • E-mail: sales@kopfinstruments.net
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DAVID KOPF INSTRUMENTS
Model 5000 Microinjection Unit
Model 5000 Microinjection Unit provides a simple and
reliable method of standardizing the use of µL syringes for
accurate, repeatable delivery of minute amounts of fluid.
It consists of an inter-changeable syringe holder plunger
drive mechanism, delivery control knob and adjustable foot
support to stabilize the needle tip.
The syringe holder firmly holds the syringe in position while
the plunger remains stationary until it is moved by the control knob. The finely calibrated control knob permits smooth,
precise dispensing of increments smaller than .001 µL of
fluid. The quick-release syringe holder allows syringes to
be refilled and repositioned rapidly and accurately.
Model 5000 Standard Accessories
(supplied with Model 5000)
Model 5001 Syringe Holder Hamilton syringes .305 barrel diameter (25 gauge)
Model 1770-C Upper Bracket Assembly for attachment to Kopf manipulator.
Optional Accessories
Model 5002 Syringe Holder Hamilton syringes .260 barrel diameter (26 gauge)
Model 5003 Micro Pipette Holder
Model 5000-G
Coarse Adjustment Handle
Model 5004 Syringe Holder Hamilton syringes .305 barrel diameter (22 gauge)
Model 5000-G Coarse Adjustment Handle is used to rotate
control knob at a rapid pace.
Model TCAT-2LV
Temperature Controller
Model TCAT-2LV Temperature Controller combined
with Model HP-1M Heating Plate and appropriate animal
rectal probe, Model RET-2-ISO (rat) or Model RET-3-ISO
(mouse) is designed to monitor and maintain a specified
body temperature of anesthetized animal during stereotaxic surgical procedures. (rectal probes not shown)
22
David Kopf Instruments • www.kopfinstruments.com
Model 980 Small Animal Spinal Unit
Model 980 Small Animal Spinal Unit is ideal for
a variety of spinal procedures. A combination of spinal clamps are included, making this unit extremely
versatile for research with various small animals. It
is easily the most flexible spinal unit available to researchers today.
Model 912 Spinal Base Plate is precision machined
and has two full length tee slots for rapid mounting
and removal of components. The top is left natural
to assure precise location of the various spinal accessories. Base plate design incorporates mounting
holes for attaching a Kopf small animal stereotaxic
frame if required.
Attached to the plate by way of tee slots are seven
base mounts with vertical posts and clamps. The
mounts are secured to the base plate by thumb
screws and tee nuts for fast, rigid clamping. No
wrenches are needed.
The posts have 3/8˝ shaft and have 4.5˝ of vertical
adjustment. The upright assembly clamps are designed with thumb screws for fast and easy height
adjustment. The design of the 980 assures ample
lateral, A/P and vertical travel of all components.
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DAVID KOPF INSTRUMENTS
Model 980 Standard Accessories
(supplied with Model 980)
Model 912 Spinal Base Plate
Dimensions: 22˝L x 12˝W x 1˝H
Weight: 27 lbs.
Model 981C Retractor (pair)
Model 982 Adjustable Base Mounts
with Post and Clamp (Qty. 7)
Model 985 Hip Spikes (pair)
Model 986C Vertebrae Clamp
Model 987 “V” Notch Spikes (pair)
Model 1780 Large Animal Spinal Unit
(supplied with Model 1780, product not shown)
Model 1712 Spinal Base Plate
Dimensions: 36˝L x 12˝W x 2¼˝H
Weight: 77 lbs.
Model 1782 Base Mounts with Adjustable Vertical
Posts (Qty. 4)
Model 1785 Adjustable Hip Spikes and Mounting
Block (pair)
Model 1786 Vertebrae Clamp and Mounting Block
(pair)
Toll Free: 1-877-352-3275 • Fax: 1-818-352-3139 • E-mail: sales@kopfinstruments.net
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Needle Pipette Puller
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DAVID KOPF INSTRUMENTS
Model 720 Single Stage Needle ­Pipette Puller
is the ideal instrument for the busy laboratory where
a number of pipettes are required. This unit is easyto-use, versatile and a reliable vertical pipette puller
with excellent repeatability.
Model 730 Two Stage Needle Pipette Puller
has truly advanced features. In addition to controllable parameters in the pulling sequence, this unit has
separate heater controls for patch clamp pipettes.
By setting or adjusting values for the first and/or
second pull, in conjunction with the other various
parameters, you can vary the length, taper and tip
to achieve an endless variety of shapes and sizes.
This is possible because all Kopf pullers have the
ability to control the parameters in the pulling sequence. Parameter controls include two heater
control knobs and digital display with 0.1 resolution,
DC regulated solenoid control and optical switch
with adjustable flags to set the length of gravity fall.
These controllable parameters coupled with heater
configuration allow a wide variety of pipettes to be
pulled.
Model 750 Two Stage Programmable ­Needle
Pipette Puller is a microprocessor controlled needle pipette puller with keypad control and digital display, capable of storing up to 100 programs.
Microprocessor control of parameters in the pulling
sequence, as well as heater size and proximity adjustment, allow a large variety of single and patch
clamp micropipettes to be produced. Patch clamp
pipettes can be produced with a one stage pull as
well as the two stage classical shape. Large tips of
five to six microns, as well as extremely fine tips,
can be obtained. Pipette glass diameters of 0.4 mm
to 3.0 mm, thin as well as heavy walled, can be held
and pulled.
In addition, an internal timer accurately measures
the pull time of the gravity fall. This reading, in combination with the known parameter settings, allow
you to duplicate the precise alignment of the heater
filaments for various pipette configurations.
Small fluctuations in heater temperature can significantly affect the shape of a pipette during pulling sequence. To help prevent this, Kopf pullers
are designed to be less susceptible to line voltage
changes. Heater voltage is divided into 20 units with
a resolution of 0.1 units.
All units pull pipettes vertically to assure straight,
concentric shapes. The slide mechanism employs
super accurate bearing components. The vertical
design is so effective that there is no need for air
jet cooling.
Specifications
Size: 9½˝W x 14½˝H x 11˝D • Weight: 37 lbs (total shipping)
Power Requirements: 100/120/220/240 VAC, 50-60 Hz via rear
panel entry module with appropriate power cord.
Solenoid Current: 0-5 amp DC current regulated with resolution of 0.1 amp. (Model 750) Solenoid Current: 0-5 amp DC
regulation.
Delay Time: 0-3 sec. with resolution of 0.001 sec.
Optical Switch: Adjustable micrometer with positive lock calibrated in .01 mm increments. (Model 750) Optical Switch: Fixed
location with adjustable flags. (Model 720 & 730)
Fuses: 4 amp, 2.5 amp (100/120 VAC); 3.15 amp., 2.5 amp
(220/240 VAC)
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David Kopf Instruments • www.kopfinstruments.com
Direct Drive and Hydraulic Micropositioners
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DAVID KOPF INSTRUMENTS
Model 2660 and 2662 Direct Drive Micropositioners are an electronically controlled direct drive micro stepping positioner
ideal for high penetration velocity with exact actual
movement of the probe.
The probe drive assembly is designed to support
linear movement with travel range of 25 mm (Model
2660) or 50 mm (Model 2662). The probe is motor
driven and has zero creep and zero backlash. Probe
design incorporates a pin for grounding the probe.
Probe drive assembly incorporates a 15 foot cable
for connecting to the electronic control assembly.
Model 2650 and 2670 Hydraulic Micropositioners are an electronically controlled hydraulic drive micro stepping positioner.
The hydraulic assembly is designed to support linear movement with travel range of 25 mm (Model
2650) or 35 mm (Model 2670).
(NOT FOR USE ON HUMANS)
Model 2660 Micropositioner
Electronic control assembly is designed for travel
speeds that can be pre-selected up to 10 pre-defined speed settings with ranges from 1 µm/sec.
to 4 mm/sec. Direct Drive maximum resolution of
0.1 µm. Rapid single motion (Burst): from 0.1 µm to
99.9 µm. Hydraulic Drive – due to the performance
characteristics of a hydraulic system, select speeds
and distances of .5 µm or higher are recommended
with maximum resolution of 0.5 µm.
Model 2650-Z Hand Control with 10 foot cable provides absolute control of the microdrive. A retract /
advance rocker switch is utilized for directional positioning. Burst and run movement are controlled
with individual pushbuttons. A reset button (recessed
guard protection) is used for resetting the control
panel display readout. We also offer Model 2650-Z-T
Hand Control with spring loaded toggle run switch
as an alternative to the standard pushbutton style
run switch.
Standard unit is a bench top set-up, rack mount accessories are quoted upon request. A 6 foot power
cord with applicable power plug is included.
All Kopf 2600 series Micropositioners are FCC, Part
15 and CE approved.
(NOT FOR USE ON HUMANS)
Model 2650 Micropositioner
Model 640
Manual Hydraulic Micropositioner
Travel range: 25 mm
(product not shown)
Toll Free: 1-877-352-3275 • Fax: 1-818-352-3139 • E-mail: sales@kopfinstruments.net
25
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DAVID KOPF INSTRUMENTS
Warranty & Disclaimer
All product components manufactured by David
Kopf Instruments are warranted to be free of defects in materials and workmanship for one year
from date of shipment. Other manufacturer's products used are subject to their warranty.
Each and every product designed, manufactured
and sold by David Kopf Instruments is intended exclusively for use in animal research and is not under
any circumstances intended for use on humans or
clinical practice on privately owned animals.
There are no express warranties except as listed
above. Additionally, such warranty becomes null
and void because of abuse, disassembly or unauthorized repair of product. Refer to maintenance
section located on www.kopfinstruments.com and/
or instruction manual included with equipment.
Because our products are intended exclusively for
use in animal research, none of the products designed, manufactured or sold by David Kopf Instruments has been approved for use on humans by the
Federal Drug Administration or any other federal or
state agency. It has always been our position that
our products are to be used exclusively in animal research. Any use of our products, except as provided
in this paragraph, shall immediately terminate any
warranty that might otherwise apply.
All express and implied warranties, including warranties of merchantability and fitness for a particular
purpose, are limited to the applicable warranty period set forth above.
Warranties will be honored only on products purchased directly through our
Tujunga office or authorized David Kopf Instruments representative.
26
David Kopf Instruments • www.kopfinstruments.com
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DAVID KOPF INSTRUMENTS
DAVID KOPF INSTRUMENTS
7324 Elmo Street
Tujunga, CA 91042
Telephone:
Toll Free:
Fax:
818-352-3274
877-352-3275
818-352-3139
sales@kopfinstruments.net
www.kopfinstruments.com
DAVID KOPF INSTRUMENTS
Precision Designs for Research
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DAVID KOPF INSTRUMENTS
Introducing an interactive summary catalog, all photos are
linked to our website to provide full product specifications.
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DAVID KOPF INSTRUMENTS
Precision Designs for Research
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2013 Price List
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DAVID KOPF INSTRUMENTS
Precision Designs for Research
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2013 Price List
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STEREOTAXIC INSTRUMENTS
SPINAL UNITS
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