LCQ Fleet Preinstallation Requirements Guide

LCQ Fleet Preinstallation Requirements Guide
LCQ Fleet
Preinstallation Requirements Guide
97055-97223 Revision A
September 2015
© 2015 Thermo Fisher Scientific Inc. All rights reserved.
Foundation and Ion Max-S are trademarks, and Accela, Ion Max, LCQ, LCQ Fleet, Thermo Scientific, and
Xcalibur are registered trademarks of Thermo Fisher Scientific Inc. in the United States.
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All other trademarks are the property of Thermo Fisher Scientific and its subsidiaries.
Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to use in the
product operation. This document is copyright protected and any reproduction of the whole or any part of this
document is strictly prohibited, except with the written authorization of Thermo Fisher Scientific Inc.
The contents of this document are subject to change without notice. All technical information in this
document is for reference purposes only. System configurations and specifications in this document supersede
all previous information received by the purchaser.
This document is not part of any sales contract between Thermo Fisher Scientific Inc. and a purchaser. This
document shall in no way govern or modify any Terms and Conditions of Sale, which Terms and Conditions of
Sale shall govern all conflicting information between the two documents.
Release history: Rev A, September 2015
Software version: Microsoft Windows 7 Professional (32-bit and 64-bit) SP1—Thermo Foundation™ 2.0 and
later, and Thermo Xcalibur 2.2 and later; Windows XP Workstation SP3—Foundation 1.0.2 SP2 or earlier,
and Xcalibur 2.1 SP1 or earlier; Thermo LTQ Tune Plus 2.7.0 and later
For Research Use Only. Not for use in diagnostic procedures.
LCQ Fleet Installation Request Form
Before completing this installation request form, read the LCQ Fleet Preinstallation Requirements Guide. For U.S.
laboratory locations, send this completed and signed form to [email protected] For
other countries or regions, go to www.thermoscientific.com/support, click Contact Us, click the email option,
,
and attach this form to your request to schedule the installation.
Laboratory setup
 1. All laboratory remodeling is complete and
complies with all relevant safety regulations.
 2. The LCQ Fleet is on site.
 3. A principal operator will be on site during the
installation/certification period.
 4. Doorways, hallways, and so on are a minimum
width of 99 cm (39 in.).
 5. Laboratory lighting is adequate.
 6. Air conditioning is adequate for temperature,
humidity, and particulate matter control.
 7. Relative humidity is 40–80%, noncondensing.
 8. The work area is free from magnetic disruption
and electrostatic discharge.
 9. A step stool is on site.
 10. A voice telephone line is installed near the system.
 11. (Optional) The laboratory has Internet access.
 12. Floor space is sufficient and flooring will support
the load.
Power
13. Main power is installed and complies with local
electrical codes.
 14. Power is free from fluctuations due to slow
changes in the average voltage or changes due to
surges, sags, or transients.
 15. Power outlets are of the correct configuration for
the power cords. See page 20.
Note NEMA type: ____________________
 16. Voltage of power outlet has been measured.
Note measured voltage:
AC line-to-ground: __________________ V
AC neutral-to-ground: _______________ V
AC line-to-neutral: __________________ V
 17. Power outlets are available for testing and cleaning
equipment.

Gas and exhaust
 18. All required gases are on site, gas lines are
installed, and appropriate gas regulators are
available. For pressures, see page 24.
Note gas types and actual purity levels:
Gas: _____________ purity:_______________
Gas: _____________ purity:_______________
 19. All gas lines are clean and have no leaks.
 20. A suitable fume exhaust system is separate from
the solvent waste and is within 2.4 m (8 ft) of the
system. See page 7 and page 29.
System setup
 21. Data system computer: (a) a new computer shows
no changes to ANY settings and has no additional
software, or (b) an existing computer meets the
software system requirements. (a) __ (b) __
 22. System setup provides for collecting solvent waste
from the API source.
 23. A new or recently cleaned HPLC system is
available that produces pulse-free, continuous flow
of 100–1000 μL/min.
 24. LC/MS-grade acetonitrile, isopropyl alcohol,
methanol, and water are available for testing the
instrument’s performance.
 25. Sufficient bench or table space is available for all
of the equipment. Note the dimensions:
Width: _____________________________
Depth: _____________________________
Height: _____________________________
Does the bench (table) have wheels? Yes__ No__
 26. Sufficient clearance is provided behind the bench
(or table). See page 5.
 27. The bench (or table) can support twice the load of
the instrument (see page 5) and is free from
vibration.
IMPORTANT Thermo Fisher Scientific reserves the right to invoice for the field service engineer’s time if the
installation requirements are not met by the installation date.
CONTINUED ON THE NEXT PAGE
For customized installations
Does your contract contain any special acceptance specifications?
If YES, attach full details of the specifications.

Yes
 No
Does the system require additional equipment?
If YES, attach full details of the additional equipment.

Yes
 No
I certify that the preinstallation requirements for the LCQ Fleet are complete and accurate.
Signature __________________________________________________ Date _____________________________
Print name _________________________________________________Telephone _________________________
Email address ________________________________________________________________________________
Principal instrument operator:
Print name _________________________________________________ Telephone ________________________
Email address ________________________________________________________________________________
Company __________________________________________________ Telephone ________________________
Address _____________________________________________________________________________________
Address _____________________________________________________________________________________
City ____________________________________ State _____________ Country __________________________
Sales order number __________________________________________
Note This form is intended to cover the essential components of your LCQ Fleet installation. However, you must
use the information in this guide and any additional information that your Thermo Fisher Scientific field service
engineer provides to ensure the proper setup of your system. After receiving this form, the field service engineer
contacts you to schedule the installation.
Regulatory Compliance
Thermo Fisher Scientific performs complete testing and evaluation of its products to ensure full compliance with
applicable domestic and international regulations. When the system is delivered to you, it meets all pertinent
electromagnetic compatibility (EMC) and safety standards as described in the next section or sections by product name.
Changes that you make to your system may void compliance with one or more of these EMC and safety standards.
Changes to your system include replacing a part or adding components, options, or peripherals not specifically
authorized and qualified by Thermo Fisher Scientific. To ensure continued compliance with EMC and safety standards,
replacement parts and additional components, options, and peripherals must be ordered from Thermo Fisher Scientific
or one of its authorized representatives.
EMC Directive 2004/108/EC
EMC compliance has been evaluated by TUV Rheinland of North America.
CFR 47, FCC Part 15, Subpart B, Class A: 2015
EN 61000-4-2: 2009
CISPR 11: 2009 + A1
EN 61000-4-3: 2006 + A1 + A2
ICES-003: 2014
EN 61000-4-4: 2004 + A1
EN 55011: 2009 + A1
EN 61000-4-5: 2006
EN 61326-1: 2013
EN 61000-4-6: 2009
EN 61000-3- 2: 2006 + A1 + A2
EN 61000-4-11: 2004
EN 61000-3-3: 2008
Low Voltage Safety Compliance
This device complies with Low Voltage Directive 2006/95/EC and harmonized standard IEC/EN/CSA/UL 61010-1,
Third Edition.
FCC Compliance Statement
THIS DEVICE COMPLIES WITH PART 15 OF THE FCC RULES. OPERATION IS SUBJECT TO
THE FOLLOWING TWO CONDITIONS: (1) THIS DEVICE MAY NOT CAUSE HARMFUL
INTERFERENCE, AND (2) THIS DEVICE MUST ACCEPT ANY INTERFERENCE RECEIVED,
INCLUDING INTERFERENCE THAT MAY CAUSE UNDESIRED OPERATION.
CAUTION Read and understand the various precautionary notes, signs, and symbols contained inside
this manual pertaining to the safe use and operation of this product before using the device.
Notice on Lifting and Handling of
Thermo Scientific Instruments
For your safety, and in compliance with international regulations, the physical handling of this Thermo Fisher Scientific
instrument requires a team effort to lift and/or move the instrument. This instrument is too heavy and/or bulky for one
person alone to handle safely.
Notice on the Proper Use of
Thermo Scientific Instruments
In compliance with international regulations: This instrument must be used in the manner specified by Thermo Fisher
Scientific to ensure protections provided by the instrument are not impaired. Deviations from specified instructions on
the proper use of the instrument include changes to the system and part replacement. Accordingly, order replacement
parts from Thermo Fisher Scientific or one of its authorized representatives.
WEEE Directive
2012/19/EU
Thermo Fisher Scientific is registered with B2B Compliance (B2Bcompliance.org.uk) in the UK and with the
European Recycling Platform (ERP-recycling.org) in all other countries of the European Union and in Norway.
If this product is located in Europe and you want to participate in the Thermo Fisher Scientific Business-to-Business
(B2B) Recycling Program, send an email request to [email protected] with the following information:
• WEEE product class
• Name of the manufacturer or distributor (where you purchased the product)
• Number of product pieces, and the estimated total weight and volume
• Pick-up address and contact person (include contact information)
• Appropriate pick-up time
• Declaration of decontamination, stating that all hazardous fluids or material have been removed from the product
For additional information about the Restriction on Hazardous Substances (RoHS) Directive for the European Union,
search for RoHS on the Thermo Fisher Scientific European language websites.
IMPORTANT This recycling program is not for biological hazard products or for products that have been medically
contaminated. You must treat these types of products as biohazard waste and dispose of them in accordance with
your local regulations.
Directive DEEE
2012/19/EU
Thermo Fisher Scientific s'est associé avec une ou plusieurs sociétés de recyclage dans chaque état membre de l’Union
Européenne et ce produit devrait être collecté ou recyclé par celle(s)-ci. Pour davantage d'informations, rendez-vous sur
la page www.thermoscientific.fr/rohs.
WEEE Direktive
2012/19/EU
Thermo Fisher Scientific hat Vereinbarungen mit Verwertungs-/Entsorgungsfirmen in allen EU-Mitgliedsstaaten
getroffen, damit dieses Produkt durch diese Firmen wiederverwertet oder entsorgt werden kann. Weitere Informationen
finden Sie unter www.thermoscientific.de/rohs.
C
Contents
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi
Related Documentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xi
Cautions and Special Notices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiii
Contacting Us . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiv
Thermo Scientific
Chapter 1
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Chapter 2
Site Preparation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3
Shipping Containers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Space and Load Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
Workbench Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Data System Layout. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
LC and MS System Layouts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Forepump . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
Telephone . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Chapter 3
Operating Environment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11
Summary of Environmental Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Humidity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
Temperature . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
Particulate Matter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Electrostatic Discharge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Lighting. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
Vibration. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
Chapter 4
Line Power . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .15
Quality of Power . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
Power Monitoring Devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
Power Conditioning Devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
Uninterruptible Power Supply. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
Circuit Breakers. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
Earth Ground . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
Electrical Outlets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
Power Supply Cords . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
Technical Assistance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
LCQ Fleet Preinstallation Requirements Guide
ix
Contents
Chapter 5
Gases and Solvents. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23
Gases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
Helium Supply . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
Nitrogen Supply . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
Compressed Air . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
Solvent Recommendations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
Chapter 6
Waste Exhaust . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .29
Exhaust System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
Solvent Waste . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
Chapter 7
Instrument Shipments. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31
Receiving Shipping Packages and Reporting Damage . . . . . . . . . . . . . . . . . . . . 31
Filing a Damage Claim Against the Carrier . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
Chapter 8
Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .33
Installation Kits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34
Customer-Supplied Hardware . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34
Basic On-Site Training . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35
Advanced Training Courses. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36
Preventive Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36
Glossary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .37
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .39
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LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
P
Preface
The LCQ Fleet Preinstallation Requirements Guide provides information for planning and
preparing your laboratory before delivery and installation of your Thermo Scientific™
LCQ™ Fleet™ mass spectrometer (MS). Read each section carefully to ensure that your lab is
ready for the system.
Contents
• Related Documentation
• Cautions and Special Notices
• Contacting Us
 To suggest changes to the documentation or to the Help
Complete a brief survey about this document by clicking the button below.
Thank you in advance for your help.
Related Documentation
The LCQ Fleet mass spectrometer includes complete documentation. In addition to this
guide, you can also access the following documents as PDF files from the data system
computer:
• LCQ Fleet Getting Connected Guide
• LCQ Fleet Getting Started Guide
• LCQ Fleet Hardware Manual
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
xi
Preface
• Ion Max and Ion Max-S API Source Hardware Manual
• Safety and Regulatory Guide
The LCQ Fleet also ships with a printed copy of the Safety and Regulatory Guide. This
guide contains important safety information about Thermo Scientific liquid
chromatography (LC) and mass spectrometry (MS) systems. Make sure that all lab
personnel have read and have access to this document.
 To view the product manuals
From the Microsoft™ Windows™ taskbar, choose Start > All Programs > Thermo
Instruments > Manuals > LCQ Fleet, and then open the PDF file to view it.
The LCQ Fleet application also provides Help.
 To view the data system Help
• From the application window, choose Help from the menu bar.
• If information about setting parameters is available for a specific view, page, or dialog
box, click Help or press the F1 key for information about setting parameters.
 To download user documentation from the Thermo Scientific website
1. Go to www.thermoscientific.com.
2. In the Search box, type the product name and press ENTER.
3. In the left pane, select Documents & Videos, and then under Refine By Category, click
Operations and Maintenance.
4. (Optional) Narrow the search results or modify the display as applicable:
• For all related user manuals and quick references, click Operator Manuals.
• For installation and preinstallation requirements guides, click Installation
Instructions.
• For documents translated into a specific language, use the Refine By Language
feature.
• Use the Sort By options or the Refine Your Search box (above the search results
display).
5. Download the document as follows:
a. Click the document title or click Download to open the file.
b. Save the file.
xii
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
Preface
Cautions and Special Notices
Make sure you follow the cautions and special notices presented in this guide. Cautions and
special notices appear in boxes; those concerning safety or possible system damage also have
corresponding caution symbols.
This guide uses the following types of cautions and special notices.
CAUTION Highlights hazards to humans, property, or the environment. Each CAUTION
notice is accompanied by an appropriate CAUTION symbol.
IMPORTANT Highlights information necessary to prevent damage to software, loss of
data, or invalid test results; or might contain information that is critical for optimal
performance of the system.
Note Highlights information of general interest.
Tip Highlights helpful information that can make a task easier.
The LCQ Fleet Preinstallation Requirements Guide contains the following caution-specific
symbols (Table 1).
Table 1. Caution-specific symbols and their meaning
Symbol
Meaning
Chemical hazard: Observe Good Laboratory Practices (GLP) when
handling chemicals. Only work with volatile chemicals under a fume
or exhaust hood.Wear gloves and other protective equipment, as
appropriate, when handling toxic, carcinogenic, mutagenic, corrosive,
or irritant chemicals. Use approved containers and proper procedures
to dispose of waste oil and when handling wetted parts of the
instrument.
Risk of electric shock: This instrument uses voltages that can cause
electric shock and/or personal injury. Before servicing, shut down the
instrument and disconnect it from line power. While operating the
instrument, keep covers on.
Risk of eye injury: Eye injury could occur from splattered chemicals or
airborne particles. Wear safety glasses when handling chemicals or
servicing the instrument.
Trip obstacle: Be aware of cords, hoses, or other objects located on the
floor.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
xiii
Preface
Contacting Us
There are several ways to contact Thermo Fisher Scientific for the information you need. You
can use your smartphone to scan a QR code, which opens your email application or browser.
Contact us
Customer Service and Sales
Technical Support
(U.S.) 1 (800) 532-4752
(U.S.) 1 (800) 532-4752
(U.S.) 1 (561) 688-8731
(U.S.) 1 (561) 688-8736
us.customer-support.analyze
@thermofisher.com
us.techsupport.analyze
@thermofisher.com
 To find global contact information or customize your request
1. Go to www.thermoscientific.com.
2. Click Contact Us, select the Using/Servicing a Product option, and then
type the product name.
3. Use the phone number, email address, or online form.
 To find product support, knowledge bases, and resources
Go to www.thermoscientific.com/support.
 To find product information
Go to www.thermoscientific.com/lc-ms.
Note To provide feedback for this document:
• Send an email message to Technical Publications ([email protected]).
• Complete a survey at www.surveymonkey.com/s/PQM6P62.
xiv
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
1
Introduction
The Thermo Scientific LCQ Fleet mass spectrometer is intended to operate under carefully
controlled environmental conditions.
You are responsible for providing a suitable location and operating environment for the
system, a source of power of acceptable quality, correct gas and solvent supplies, and proper
waste and exhaust systems.
CAUTION Operating a system or maintaining it outside the power and operating
environment specifications described in this guide might cause failures of many types. The
repair of such failures is specifically excluded from the Thermo Fisher Scientific standard
warranty and service contract coverage.
Note
• For preinstallation support and additional information, contact your local Thermo
Fisher Scientific office.
• The Glossary defines some of the terms used in this guide.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
1
1
2
Introduction
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
2
Site Preparation
Before a Thermo Fisher Scientific field service engineer can install your LCQ Fleet MS, make
sure your laboratory meets these requirements:
• When transporting the equipment to the designated site, you have a wide turning radius
through entrances, hallways, elevators, and so on. Remember to consider the width of the
device transporting the shipping container to the lab.
• You have workbenches that are strong enough to support the weight of the instruments.
You are responsible for providing an acceptable installation site before the Thermo Fisher
Scientific field service engineer arrives.
Contents
• Shipping Containers
• Space and Load Requirements
• Forepump
• Telephone
Shipping Containers
You system ships in multiple containers. Table 2 lists the overall dimensions and weights of
the shipping containers for the LCQ Fleet system that are too large to carry by hand. Use this
information to determine how to transport the containers and remove their contents. Other
equipment in your order have their own smaller shipping containers and do not require
special considerations. The chemicals kit typically arrives earlier than the other parts of your
order.
See “Installation Kits” on page 34 for the kit part numbers.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
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2
Site Preparation
Space and Load Requirements
Table 2. Shipping container dimensions and weightsa
Box
a
Size
Weight
Content
1
104 × 94 × 135 cm (l × w × h)
(41 × 37 × 53 in.) (l × w × h)
181 kg
(400 lb)
LCQ Fleet MS in the system crate
2
71 × 71 × 132 cm (l × w × h)
(28 × 28 × 52 in.) (l × w × h)
62 kg
(136 lb)
Data system and accessories (in utility
box located in system crate)
3
79 × 31 × 46 cm (l × w × h)
(31 × 12 × 18 in.) (l × w × h)
50 kg
(110 lb)
Forepump
The height and weight measurements include the shipping pallets.
Space and Load Requirements
Table 3 lists the dimensions and weights for the data system and LCQ Fleet system modules.
Use this information to ensure that all workbenches are large enough and strong enough to
support the modules.
Table 3. Space and load requirementsa for the system modules
Width (w)
cm (in.)
Height (h)
cm (in.)
Depth (d)
cm (in.)
Weight
kg (lb)
LCQ Fleet mass spectrometer
76 (30)
56 (22)
59 (23)b
104 (230)
Forepump
58 (23)
25 (10)
18 (7)
44 (97)
(Optional) LC systemc
38 (15)
73 (29)
51 (20)
68 (150)
Computer, mini-tower
17.5 (7)
36 (14.2)
41.7 (16.4)
9.4 (21)
Monitor
57 (22.4)
37 (14.6)
18 (7.1)
6.2 (13.7)
Ethernet switch
15.4 (6.1)
2.9 (1.14)
11 (4.3)
0.165 (0.4)
45 (18)
32 (12.4)
41 (16)
16 (35)
Modules
LC/MS system
Data system
(Optional) Printer
4
a
These values are approximate.
b
Excludes the API source housing.
c
These values are for an LC system consisting of a Thermo Scientific Accela™ PDA Detector, Accela Autosampler,
and Accela pump and excludes the solvent bottles and tubing.
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
2 Site Preparation
Space and Load Requirements
This section discusses the following:
• Workbench Requirements
• Data System Layout
• LC and MS System Layouts
Workbench Requirements
Table 4 lists the recommended minimum surface dimensions and load capacities for each
workbench. Thermo Fisher Scientific recommends that workbenches have a load capacity of
at least twice the combined weight of all expected devices. You must provide the workbenches
for your system.
Table 4. Minimum workbench surface dimensions and load capacities
Equipment
Surface
Load capacity
Data system
122 × 91 cm (48 × 36 in.)
64 kg (140 lb)
LC system and LCQ Fleet MS
152 × 91 cm (60 × 36 in.)
209 kg (460 lb)
Follow these clearance guidelines for the workbenches:
• Place the data system and LC/MS workbenches adjacent to each other to prevent strain
on the interconnecting Ethernet communications cables.
CAUTION Safety and EMC regulations require the use of Category 5 shielded
Ethernet communications cables, maximum 3 m (10 ft) long.
• For all systems, allow for a minimum vertical clearance of 92 cm (36 in.) between the top
of the system and any shelves above it.
• For all systems, allow for 61 cm (24 in.) minimum horizontal clearance on the right side
of the system for access to the Main Power Switch.
• For an LC/MS system, allow for a minimum horizontal clearance of 8 cm (3 in.) between
the wall and the back of the system for proper air circulation and clearance of the installed
gas lines and tubing.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
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2
Site Preparation
Space and Load Requirements
Figure 1 shows the top view (footprint) for the system workbenches.
Figure 1.
Top view and recommended placement of the workbenches (tables)
Laboratory wall
Minimum 8 cm (3 in.) horizontal clearance
LC/MS table
Data system table
Data System Layout
Figure 2 shows an optional layout for the data system. Not all connections are shown; for
connection information, refer to the LCQ Fleet Getting Connected Guide.
Figure 2.
Workbench for the data system
122 cm (4 ft)
Monitor
Data system
computer
Printer
(optional)
Ethernet switch
120 Vac electrical outlets
(for North America)
6
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
2 Site Preparation
Space and Load Requirements
LC and MS System Layouts
Figure 3 show the recommended layout for the LC/MS system. Not all connections are
shown; for connection information, refer to the LCQ Fleet Getting Connected Guide.
CAUTION For information about the LC drainage systems, refer to the LC instrument
manual.
Figure 3.
Workbench for the LCQ Fleet mass spectrometer and the optional Accela LC system
10 cm (4 in.)
38 cm
(15 in.)
76 cm
(30 in.)
Accela
LC system
LCQ Fleet mass spectrometer
114 cm
(45 in.)
Ethernet cables
120 Vac
electrical outlets
(for North America)
External vent for the
solvent trap connected
to the API source
Thermo Scientific
230 Vac
electrical outlets
External vent for
the forepump
exhaust
Solvent trap
Forepump with optional
noise reduction cover
LCQ Fleet Preinstallation Requirements Guide
7
2
Site Preparation
Forepump
Forepump
The LCQ Fleet system includes one forepump. Depending on available space, you have two
options for the placement of the forepump and for connecting the vacuum hose from the
mass spectrometer to the forepump:
• If there is space below the workbench, place the forepump underneath, immediately
behind the mass spectrometer. Either run the vacuum hose behind the workbench or
make a 6.4 cm (2.5 in.) diameter hole through the workbench for the vacuum hose and
the power supply cord from the forepump.
• If there is no space below the workbench, place the forepump on the floor in front of the
mass spectrometer.
CAUTION Trip hazard. Whenever possible, provide space under the workbench for the
forepump. If placed in front of the mass spectrometer, the forepump becomes a trip
hazard.
CAUTION
• Do not place the forepump on a shelf or other surface connected to the workbench.
Vibration from the pump can affect system performance.
• The exhaust hose tubing acts as a trap for exhaust fumes that would otherwise
recondense in the forepump oil.
–
To maintain forepump integrity, route the exhaust tubing from the exhaust port
down to the floor, not from the forepump vertically toward the ceiling.
–
Run the exhaust hose at floor level for a minimum of 2 m (79 in.) before it
reaches the external exhaust system.
Figure 4 shows the blue exhaust hose connected to the optional oil mist filter, which connects
to the exhaust port of the forepump. For information about connecting the forepump, refer to
the LCQ Fleet Getting Connected Guide and the installation instructions provided with the
forepump.
8
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
2
Figure 4.
Site Preparation
Telephone
Forepump exhaust system connections
Vacuum port
EDWARDS
Oil Mist Filter EMF 20
Forepump
Optional noise
reduction cover
(not shown)
Optional oil
mist filter
Blue hose connects
to external exhaust
system
Telephone
Make sure all of the laboratory staff have access to a telephone (landline or mobile) in the lab
near the system so that, if necessary, you can operate the mass spectrometer while speaking
with Thermo Fisher Scientific Technical Support. For a landline connection, make sure that
the telephone jack is within 1.8 m (6 ft) of the mass spectrometer.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
9
2
Site Preparation
Telephone
10
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
3
Operating Environment
Attention to the operating environment ensures continued high performance of your Thermo
Scientific LC/MS system. Any expenditures for air conditioning are more than offset by good
sample throughput and reduced repair costs.
For proper operation of the system, you are responsible for providing the operating
environment described in this chapter.
Contents
• Summary of Environmental Requirements
• Humidity
• Temperature
• Particulate Matter
• Electrostatic Discharge
• Lighting
• Vibration
Summary of Environmental Requirements
Table 5 lists the environmental requirements for the designated laboratory.
Table 5. Summary of environmental requirements (Sheet 1 of 2)
Parameter
Specification
Humidity
40–80%, noncondensing
Temperature
• Standard performance: 15–27 °C (59–81 °F)
• Optimum performance: 18–21 °C (65–70 °F)
• Ambient temperature: Fluctuations of less than
1 °C or 2 °F over a one-hour period
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
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3
Operating Environment
Humidity
Table 5. Summary of environmental requirements (Sheet 2 of 2)
Parameter
Specification
Particulate Matter
Does not exceed 3 500 000 particles per cubic meter
(100 000 particles per cubic foot).
Electrostatic Discharge (ESD)
Follow the stated precautions to help prevent ESD.
Lighting
• Operating: Typical laboratory lighting
• Cleaning: Use a small, high-intensity lamp
Vibration
Choose a lab location that is vibration-free.
Humidity
Maintain the relative humidity in the designated lab at 40–80 percent, without condensation.
Operating a Thermo Scientific mass spectrometer in an environment with very low humidity
can cause the accumulation and discharge of static electricity that can shorten the life of the
electronic components. Operating the mass spectrometer in an environment with high
humidity can cause condensation, oxidation, and short electronic circuits. It can also cause the
accumulation of dust that can block filters on the cooling fans.
To ensure that the lab is always within the required temperature and humidity specifications,
Thermo Fisher Scientific recommends that you install a temperature and humidity monitor in
the lab.
Temperature
For precision instruments, such as the Thermo Scientific LCQ Fleet MS, maintain the lab
temperature at 15–27 °C (59–81 °F). For optimum performance, maintain the lab
temperature at 18–21 °C (65–70 °F). Temperature control is vital to acquiring accurate mass
measurements. Therefore, make sure that during any one-hour period, ambient temperature
fluctuations are less than 1 °C or 2 °F.
IMPORTANT
• All electronic components generate heat while operating. This heat must dissipate to
the surrounding air for the components to continue to operate reliably.
• Do not locate the instrument under an air duct, near windows, or near heating and
cooling sources. As the lab ambient temperature increases, the LCQ Fleet system
reliability decreases.
12
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3
Operating Environment
Particulate Matter
There must be good air flow around the system, and the air conditioning system must
maintain a constant temperature in the immediate vicinity of the instrument. Table 6 lists the
approximate heat output (power) for the system. For the heat output of your specific LC
devices, refer to the instrument manuals.
Table 6. Maximum heat output
Heat output
(W)
Heat output
(BTU/h)
LCQ Fleet MS
2300
7848
LC system and data systema
1950
6654
Total
4250
14 502b
Module
a
Approximate values. The actual values depend on your installed equipment.
b
The maximum heat output for an LC/MS system and data system.
Particulate Matter
Make sure that the air in the lab is free from excessive dust, smoke, or other particulate matter
in excess of 5 μm—that is, fewer than 3 500 000 particles per cubic meter (100 000 particles
per cubic foot).
Dust can clog the air filters, causing a reduction in air flow around the electronic components.
Dust on electronic components can act as an insulating blanket, which reduces the transfer of
heat from the components to the surrounding air.
Electrostatic Discharge
Electrostatic discharge (ESD) can damage the electronic components of the LCQ Fleet MS.
Most Thermo Scientific instruments are designed to withstand ESD up to 4 kV (air
discharge) and 4 kV (contact discharge) with all panels in place. However, removing the
panels and handling the printed circuit boards (PCBs) without proper precautions might
damage the electrical components or cause them to fail prematurely.
Because of ESD, take the following precautions, especially when operating the system at the
lower end of the relative humidity specification:
• Use a static-dissipating floor covering (such as tile or conductive linoleum) in the lab.
• Use laboratory chairs covered with natural fibers or other static-dissipating material.
• Wear a laboratory coat and clothing made of natural fiber or other static-dissipating
material when operating the instrument.
• Keep Styrofoam cups or packing materials away from the instrument.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
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3
Operating Environment
Lighting
Lighting
Good lighting makes any work area more enjoyable. Thermo Fisher Scientific recommends
that you use a small, high-intensity lamp when cleaning the instrument components.
Vibration
Select a lab location that is free from vibration—floors at ground level usually have less
vibration. When selecting the location, be aware of adjacent rooms with equipment that could
transmit vibrations through the floor to the instrument workbench.
Because of the natural vibration of the forepump during operation, install the forepump on
the floor under the instrument.
14
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
4
Line Power
The quality of line power (ac mains power system) delivered to the LCQ Fleet system can
affect its performance and longevity. To ensure that the system performs optimally and is not
damaged by line power fluctuations, verify that the lab’s electrical supply complies with all
power quality requirements.
You are responsible for providing a power source of acceptable quality to operate the system.
CAUTION To support compliance and safety requirements, all devices connected between
the power source and the mass spectrometer must be certified by recognized organizations
for your country (for example, UL, CSA, SEMKO, VDE, or TÜV).
Such devices include the power supply cords, electrical outlets, circuit breakers,
uninterruptible power supplies (UPSs), and so on.
Contents
• Quality of Power
• Power Monitoring Devices
• Power Conditioning Devices
• Uninterruptible Power Supply
• Circuit Breakers
• Earth Ground
• Electrical Outlets
• Power Supply Cords
• Technical Assistance
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
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4
Line Power
Quality of Power
Quality of Power
Establishing the quality of power supplied to the LC/MS system is very important for these
reasons:
• Constant high line voltage, impulses, or surges in voltage can cause overheating and
component failures.
• Constant low line voltage or sags in voltage can cause the system to function erratically or
not at all.
• Transients—even a few microseconds in duration—can cause electronic devices to
degrade or fail catastrophically, shortening the lifetime of the system.
Before a Thermo Fisher Scientific field service engineer arrives to install your system, make
sure the line voltage is stable and within the recommended specifications. The line voltage
must be free of fluctuations due to slow changes in the average sags, surges, transients, or
voltage. For the mass spectrometer’s electrical ratings, see Table 8 on page 19.
Table 7 lists the definitions for the three most common voltage disturbances.
Table 7. Common voltage disturbances
Voltage disturbance
Definition
Slow average
A gradual, long-term change in the average root mean square
(RMS) voltage level, with typical durations greater than 2 s
Sags and surges
Sudden changes in the average RMS voltage level, with typical
durations between 50 ms and 2 s
Transients or impulses
A brief voltage spike of up to several thousand volts, with
typical durations up to 50 μs
Power Monitoring Devices
Several devices are available to monitor the quality of the line power. These devices provide a
continuous record of line performance by analyzing and printing out data for the three most
common voltage disturbances (see Table 7).
In the first two cases, the time interval recording indicates the duration and the amplitude of
the disturbance. A power line disturbance analyzer detects and records most types of line
power problems. The Dranetz™1 system is an example of a suitable analyzer. In some
countries, electrical equipment suppliers have power line analyzers to rent.
1
16
Thermo Fisher Scientific does not endorse any power monitoring company, nor does it endorse products other
than its own. Companies and products listed in this guide are given as examples only.
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
4 Line Power
Power Conditioning Devices
Monitor the power line 24 hours a day for seven consecutive days. If inspection of the
printout indicates disturbances, stop the test and take corrective action. Monitor the power
again as previously described.
Power Conditioning Devices
You can correct a line voltage problem by using various line voltage conditioning devices. If
the power regulation is good but the power line disturbance analyzer shows transient voltages,
an isolation/noise-suppression transformer can resolve the problem. For both transient and
regulation problems, consider the use of power conditioners to control these problems. See
the CAUTION statement on page 15.
CAUTION Any conditioning devices installed with the system must be able to handle the
potentially high currents that are drawn during the initial startup of the system. For
example, during startup, the forepump can draw a high inrush current.
Because the LCQ Fleet system requires the use of a forepump, it draws an inrush current.
The maximum inrush (start) current for the forepump (Edwards Model E2M30)
connected to the mass spectrometer is 20 A. The average duration of the forepump’s
inrush current is less than 1 s. Therefore, this initial energy demand from the ac power
line is very low.
Thermo Scientific systems are protected from overcurrents with time-delay fuses and
active switches. For more information, contact your Thermo Fisher Scientific field service
engineer.
When the line voltage is free from voltage sags, surges, and impulses but is more than
10 percent outside of the voltage specifications, a buck/boost transformer can lower (buck
10 percent) or raise (boost 10 percent) the line voltage as appropriate for the rated voltage.
Order the Buck/Boost Transformer Kit (P/N OPTON-01460) from Thermo Fisher Scientific
San Jose. Each buck/boost transformer is encased in a metal housing approximately
13 × 13 × 26 cm (5 × 5 × 10 in.) and ships with a 2 m (6.5 ft) power supply cord. Have a
certified electrician install the transformer, using the installation instructions that are
included. Then, install the LCQ Fleet system.
CAUTION Systems installed in areas with 208 Vac power can experience voltage sags
during high use periods that might place the line voltage below the operating parameters
discussed in this section. In this case, protect the system by using a buck/boost
transformer to ensure that power stays within the specified parameters.
Uninterruptible Power Supply
If your local area is susceptible to corrupted power or power disruptions, install an
uninterruptible power supply (UPS) in the lab. See the CAUTION statement on page 15.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
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4
Line Power
Circuit Breakers
Circuit Breakers
Make sure that each circuit breaker is suitably rated so that the equipment connected to the
electrical outlets does not lose power by triggering a current overload condition. For added
protection, install a surge protector at the input to the circuit breaker panel.
Earth Ground
Make sure that the earth ground connections in the lab are hardwired to the same ground
used for the main circuit breaker panel. Multiple external ground points can cause noise
current to flow through the ground loop that is formed.
Electrical Outlets
The lab requires several grounded, electrical outlets that are suitably rated. In addition to the
required number of electrical outlets for the LCQ Fleet system, Thermo Fisher Scientific
recommends that there be several additional outlets close to the work area for testing and
cleaning equipment, such as an oscilloscope and sonicator.
CAUTION To avoid an electric shock, always have a certified electrician install any new
wall receptacles.
Installing a complete LCQ Fleet system can require extensive electrical resources. Plan the
power system properly, with several outlets, to make sure that you can connect all of the
equipment. Table 8 lists the electrical ratings for the modules in a typical lab setup. For the
LC modules, refer to the manufacturer’s manuals. To prevent overloading the outlets, select
outlets with a load rating that is suitable for the expected total current per outlet.
IMPORTANT In North America, the LC/MS system requires both 120 and 230 Vac
single-phase electrical outlets.
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LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
4 Line Power
Electrical Outlets
Table 8. Electrical ratings and required outlets per module
Voltage
(Vac)
Current
(A)
Required
outlets
Computer, mini-tower
100–240
5
1
Monitor
100–240
1.5
1
Ethernet switch
100–240
<1
1
110
–or–
220
8.6
–or–
4.2
1
230
15
1
High-intensity lamp (for instrument maintenance)
–
–
1
Laboratory stereoscope (for inspecting fused-silica
parts)
–
–
1
Module
Data system
(Optional) Printer, laser
MS systema
LCQ Fleet smass spectrometer
Optional devicesb
Total number of electrical outletsc
7+
a
The current draw excludes the forepump.
b
Refer to the equipment manual for the electrical rating.
c
Remember to add the number of outlets required for your LC system.
IMPORTANT After planning the location of the workbenches (see Chapter 2), consider
the following before installing the electrical outlets:
• Each module’s location and whether each requires a 120 or 230 Vac outlet (see
Table 8)
• The minimum number of outlets needed for a given voltage and adding the number
of outlets needed for any additional lab equipment (see Table 8)
• The length of the power supply cords (see Power Supply Cords)
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
19
4
Line Power
Power Supply Cords
Power Supply Cords
Your order includes two detachable power supply cords for the LCQ Fleet MS: one for North
American destinations and the other for international destinations. Both power supply cords
measure 2.5 m (8 ft). However, the international power supply cord does not include the plug
that connects to the electrical outlet. You must provide a suitable 230 Vac plug that meets
your country’s compliance requirements. Table 9 lists the plug types and electrical ratings for
various countries and territories.
The peripheral components (data system computer, monitor, and Ethernet switch) ship with
detachable power supply cords that are appropriate for your country or territory. The power
supply cord for the optional laser printer has either a NEMA 5-15P plug or a European
CEE 7/7 (Schuko) plug, which is rated 16 A, 220 Vac. The power supply cords for the data
system modules are 1.8 m (6 ft).
Note The electrical code for your area might require the use of another type of plug and
receptacle (electrical outlet).
Table 9. Power plug type and rating by country or region
20
Destination
Plug type
Electrical rating
North America
NEMA 5-15P
15 A, 125 Vac
NEMA 6-15P
15 A, 250 Vac
China
GB 2099-1,GB 1002-1
10 A, 250 Vac
Europe
CEE 7/7
10 A, 250 Vac
India
BS 546
15 A, 250 Vac
Japan
JIS 8303
15 A, 125 Vac
Switzerland
SEV 1011
10 A, 250 Vac
United Kingdom and
Ireland
BS 1363
5 A, 250 Vac
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
4 Line Power
Power Supply Cords
Figure 5 through Figure 7 show the specific plug configurations listed in Table 9 on page 20.
Figure 5.
Plug configurations for North America
NEMA 6-15P
receptacle and plug
NEMA 5-15P
receptacle and plug
Figure 6.
Plug configurations for Europe
CEE 7/7 (Schuko) plug
(Europe)
BS 1363 plug
(UK and Ireland)
SEV 1011 plug
(Switzerland)
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
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4
Line Power
Technical Assistance
Figure 7.
Plug configurations for Asia
GB 2099-1, GB 1002-1 plug
(China)
JIS 8303 plug
(Japan)
BS 546 plug
(India)
Technical Assistance
Occasionally, you might encounter line power sources with unacceptable quality that
adversely affect the operation of the LCQ Fleet system. You are responsible for correcting any
line power problems. Contact Thermo Fisher Scientific for assistance in monitoring the line
voltage in your lab and in selecting a line conditioner.
Specifying power conditioning equipment is a complex task that is best handled by a company
or consultant specializing in that field. Contact Thermo Fisher Scientific for assistance in
locating a power consultant in your area.
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5
Gases and Solvents
The LCQ Fleet MS requires high-purity (HP) helium and nitrogen gases, and solvents. The
Thermo Fisher Scientific field service engineer might also require certain solvents for the
installation verification of your system.
You are responsible for providing the correct gas, solvent, and regulators to operate the system.
Contents
• Gases
• Solvent Recommendations
Gases
The LCQ Fleet MS uses helium as the damping gas and collision gas in the linear trap.
Nitrogen is used as the atmospheric pressure ionization (API) sheath gas, auxiliary gas, and
sweep gas. The instrument can use large amounts of gases during daily operations. Make sure
that the gases are delivered with the necessary pressure and purity.
Figure 8 shows the location of the gas connections on the back of the instrument. For
information about connecting the gas lines, refer to the LCQ Fleet Getting Connected Guide.
Figure 8.
Gas connections on the back of the LCQ Fleet
Nitrogen In
Helium In
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
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5
Gases and Solvents
Gases
CAUTION
• Contaminants introduced during the installation of house lines used for gas delivery
can cause damage to the instrument. Make sure that all gas lines used with the
instrument have been cleaned of all particulates and oils. You are responsible for any
damage to the instrument caused by contaminants introduced from your gas delivery
system.
• Because particulate filters can be a source of contamination, Thermo Fisher Scientific
does not recommend their use.
Helium Supply
The LCQ Fleet MS uses helium as the damping and collision gas. The helium supply
requirements are as follows:
• UHP gas of 99.999%, with less than 1.0 ppm each of water, oxygen, and total
hydrocarbons
• 275 ±70 kPa (40 ±10 psi) gas pressure
To dispense helium from a tank (such as one containing 245 ft3 of helium), use a regulator
suitable for helium. Use either stainless steel tubing or the provided copper tubing for the
helium gas line, and make sure that it is free of oil and preferably flame dried.
Note
• After you start using the LCQ Fleet MS, do not shut off the helium gas. Optimum
performance requires a continuous flow of helium.
• If you intend to use helium for sparging your LC solvents, you must have a second
tank and regulator.
Nitrogen Supply
The LCQ Fleet MS uses nitrogen as the API sheath, auxiliary, and sweep gases. The nitrogen
supply requirements are as follows:
• HP gas of 99%
• 690 ±140 kPa (100 ±20 psi) gas pressure
Note You must provide a regulator for the nitrogen supply that you can adjust over the
specified pressure range.
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5
Gases and Solvents
Gases
When operating 24 hours a day and 7 days a week, the LCQ Fleet MS typically consumes
5560–26700 L (196–943 ft3) of nitrogen gas daily. Thermo Fisher Scientific recommends
one of the following sources for the nitrogen supply:
• A large, sealed, thermally insulated cylinder containing liquid nitrogen from which the
nitrogen gas is boiled off. The selected Dewar flask must be able to provide the required
gas flows and a head pressure of 690 ±140 kPa (100 ±20 psi) going to the instrument.
• A nitrogen generator that can generate up to 21 L/min (44.5 ft3/h) of HP nitrogen with a
head pressure of 690 ±140 kPa (100 ±20 psi).
Note When you turn on the system, the initial nitrogen surge might exceed the capacity
of the nitrogen generator. This sudden surge causes a flow rate drop that can trigger a low
nitrogen warning from the instrument. If low nitrogen warnings happen frequently, call
your Thermo Fisher Scientific field service engineer.
Compressed Air
If you intend to connect the Thermo Scientific FAIMS (high-Field Asymmetric waveform Ion
Mobility Spectrometry) module to the mass spectrometer during the initial setup or at a later
date, plan ahead and have a compressed air supply line installed. You use the compressed air to
actively control the temperature of the electrodes in the temperature control module that is
part of the FAIMS module assembly. The mass spectrometer does not require compressed air.
The compressed air requirements are as follows:
• 276–414 kPa (40–60 psi) gas pressure
• Supply line tubing, 1/4 in. OD, connected to the FAIMS temperature control port
Note Thermo Fisher Scientific strongly recommends the use of a desiccant air dryer to
remove some of the moisture, oil, and dirt that might be present in the compressed gas.
For additional information about the gas connections and operation, refer to the FAIMS
Operator’s Manual provided with the module.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
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5
Gases and Solvents
Solvent Recommendations
Solvent Recommendations
CAUTION Avoid exposure to potentially harmful materials.
By law, producers and suppliers of chemical compounds are required to provide their
customers with the most current health and safety information in the form of Material
Safety Data Sheets (MSDSs) or Safety Data Sheets (SDSs). The MSDSs and SDSs must
be freely available to lab personnel to examine at any time. These data sheets describe the
chemicals and summarize information on the hazard and toxicity of specific chemical
compounds. They also provide information on the proper handling of compounds, first
aid for accidental exposure, and procedures to remedy spills or leaks.
Read the MSDS or SDS for each chemical you use. Store and handle all chemicals in
accordance with standard safety procedures. Always wear protective gloves and safety
glasses when you use solvents or corrosives. Also, contain waste streams, use proper
ventilation, and dispose of all laboratory reagents according to the directions in the MSDS
or SDS.
As specified in Table 10, use only LC/MS-grade solvents and solutions for operating and
maintaining the LCQ Fleet system. Installation of the instrument requires LC/MS-grade
methanol and water. Installation of some systems might also require solvent modifiers.
Note Visit www.fishersci.com for a wide variety of solvents and consumables for purchase.
Table 10. Recommended solvents and solutions (Sheet 1 of 2)
Grade
Sizea
Part number
2-Propanol
Optima™ LC/MS
Amber glass, 4 L
A461-4
Acetonitrile
Optima LC/MS
Amber glass, 4 L
A955-4
Methanol
Optima LC/MS
Amber glass, 4 L
A456-4
Water
Optima LC/MS
Amber glass, 4 L
W6-4
0.1% Formic acid in acetonitrile
Optima LC/MS
Amber glass, 4 L
LS120-4
0.1% Formic acid in water
Optima LC/MS
Amber glass, 4 L
LS118-4
0.1% Trifluoroacetic acid in acetonitrile
Optima LC/MS
Amber glass, 4 L
LS121-4
0.1% Trifluoroacetic acid in water
Optima LC/MS
Amber glass, 4 L
LS119-4
Acetic acid (modifier)
Optima LC/MS
Ampule, 10 × 1 mL
A113-10X1AMP
Ammonium acetate
Optima LC/MS
Amber glass, 50 g
A114-50
Ammonium formate
Optima LC/MS
Amber glass, 50 g
A115-50
Product
Solvents
Blends
Additives
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5 Gases and Solvents
Solvent Recommendations
Table 10. Recommended solvents and solutions (Sheet 2 of 2)
a
Product
Grade
Sizea
Part number
Formic acid (modifier)
Optima LC/MS
Ampule, 10 × 1 mL
A117-10X1AMP
Trifluoroacetic acid
Optima LC/MS
Ampule, 10 × 1 mL
A116-10X1AMP
Size for the stated part number
IMPORTANT
• Some solvent impurities are transparent to a UV-Vis detector. Therefore, some
HPLC-grade solvents might contain contaminants that interfere with the
performance of the instrument. To operate the instrument, choose HP solvents with
minimum contamination.
• Do not filter solvents. Filtering solvents can introduce contamination.
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LCQ Fleet Preinstallation Requirements Guide
27
5
Gases and Solvents
Solvent Recommendations
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LCQ Fleet Preinstallation Requirements Guide
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6
Waste Exhaust
The waste and exhaust arrangements can affect the proper performance of the LCQ Fleet
system. You must vent vacuum and solvent wastes separately, and collect and dispose of wastes
properly.
You are responsible for providing the proper waste and exhaust systems that are required to
operate the system.
Contents
• Exhaust System
• Solvent Waste
Exhaust System
For proper operation of the forepump, Thermo Fisher Scientific strongly recommends that
you connect the forepump to an efficient fume exhaust system. The forepump eventually
exhausts much of what is introduced into the mass spectrometer, including the small amount
of oil vapor that a mechanical pump can emit.
Note Most API applications contribute to solvents accumulating in the forepump.
Although Thermo Fisher Scientific recommends that you periodically open the ballast
valve (on the top of the pump) to purge the accumulated solvents, opening the valve
might allow a large volume of volatile solvent waste to enter the fume exhaust system.
Choose an exhaust system that can accommodate the periodic purging of these solvents.
The frequency of the purging depends on the throughput of the system.
The forepump requires one 15 mm (0.6 in.) OD exhaust port. The exhaust system for the
forepump must be able to accommodate an initial inrush flow rate of 3 L/min (6.4 ft3/hr) and
a continuous flow rate of 1 L/min (2 ft3/hr).
IMPORTANT The port for the lab exhaust system must be close enough to the forepump
so that the exhaust hose is at floor level for a minimum of 2 m (78.7 in.). This hose acts as
a trap for exhaust fumes that would otherwise recondense in the forepump oil.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
29
6
Waste Exhaust
Solvent Waste
Equip your lab with at least two fume exhaust systems:
• The analyzer optics can become contaminated if the API source drain tube and the (blue)
exhaust tubing from the forepump connect to the same fume exhaust system. Route the
(blue) exhaust tubing from the forepump to a dedicated fume exhaust system.
CAUTION Do NOT run the forepump exhaust lines vertically near the forepump.
Solvents and oils can condense in these lines and flow back into the pump, causing
pump damage, and the loss of pump capability. Figure 4 on page 9 shows the
forepump tubing connected to the back of the instrument.
• Do not vent the PVC drain tube (or any vent tubing connected to the waste container) to
the same fume exhaust system that connects to the forepump. Vent the waste container to
a dedicated fume exhaust system. The exhaust system for the API source must
accommodate a flow rate of up to 30 L/min (64 ft3/h).
Solvent Waste
The LCQ Fleet MS comes with parts to collect the solvent waste from the API source.
Because the Ion Max API source can accommodate high flow rates, you must use a method of
collecting the solvent waste that avoids pressure buildup in the source. Figure 3 on page 7
shows the solvent waste exhaust tubing connected to the bottom of the API source housing
located on the front of the instrument.
Use these guidelines for the API source drain:
• Use the PVC tubing provided with the solvent waste container to connect the solvent
waste container to a fume exhaust system. Do not connect silicone tubing to the API
source drain. If silicone tubing connects to the outlet drain, you might observe
background ions at m/z 536, 610, and 684.
• Use the Teflon source drain adapter as described in the LCQ Fleet Getting Connected
Guide. Do not connect Tygon™ tubing directly to the API source drain. At high
temperatures, Tygon releases volatile contaminates.
• To prevent solvent waste from backing up into the mass spectrometer, make sure that all
tubing is above the level of liquid in the waste container as follows:
–
Tygon tubing from the mass spectrometer to the solvent waste container
–
PVC tubing from the waste container to the exhaust system
For information about connecting the API source housing drain, refer to the LCQ Fleet
Getting Connected Guide.
30
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
7
Instrument Shipments
Electronic equipment carriers that specialize in the handling and transport of delicate
machinery ship the LCQ Fleet MS to your site. When the instrument arrives, move it to a
protected indoor location. If you have questions about moving your instrument, contact your
local office for Thermo Scientific San Jose products (see “Contacting Us” on page xiv).
CAUTION Heavy object. Never lift or move the instrument by yourself; you can suffer
personal injury or damage the instrument.
On the occasion when shipments arrive that appear damaged, take these immediate actions.
Contents
• Receiving Shipping Packages and Reporting Damage
• Filing a Damage Claim Against the Carrier
Receiving Shipping Packages and Reporting Damage
Upon delivery, visually inspect for any damage to the shipment packages.
 To visually inspect for damage
Carefully inspect for obvious damage or evidence of rough handling.
If the instrument shipping container, ShockWatch™, or other indicators show visible
evidence of damage or mishandling, do NOT open the container.
Follow the next procedure, and then call your Thermo Fisher Scientific sales representative for
further instructions.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
31
7
Instrument Shipments
Filing a Damage Claim Against the Carrier
 To record damages on the receiving documents
1. Read the information in Filing a Damage Claim Against the Carrier to determine which
parties might be responsible for filing a claim against the carrier.
2. On all copies of the receiving documents, note any apparent external damage and briefly
describe the extent of the damage.
3. Have the driver sign or initial next to your comments to signify agreement with your
observations.
4. Report the list of damages to your Thermo Fisher Scientific representative.
IMPORTANT Freight insurance requires that you note obvious damage on the
receiving documents. Thermo Fisher Scientific does not accept liability for damage if
materials are received with obvious damage AND the damage is not recorded on the
receiving documents.
Filing a Damage Claim Against the Carrier
If the instrument is damaged in transit, the shipment method determines the party who
assumes the risk of damage and files a claim against the carrier—Thermo Fisher Scientific or
the purchaser. To determine the shipment method for instruments shipped from the San Jose,
CA site, check the sales agreement or the sales quote.
Table 11 lists the party who files the damage claim against the carrier for instruments
damaged in transit based on the shipment method.
Table 11. Shipment methods for delivery from the San Jose, CA site to domestic and international
destinations
Destination
Shipment method
Domestic
(United States)
Destination or Origin—Thermo Fisher
Scientific pays the carrier.
Party responsible for filing a
damage claim
Thermo Fisher Scientific
Origin—The purchaser pays the carrier. Purchaser
International
32
Carriage Paid To (CPT) named
destinationa
Purchaser
Carriage and Insurance Paid (CIP) to
named destinationb
Thermo Fisher Scientific
a
Unless specified differently, Thermo Fisher Scientific uses this shipment method for international shipments.
b
Under special circumstances, Thermo Fisher Scientific uses this shipment method for international shipments.
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
8
Installation
Complete all preparations described in the previous chapters before your Thermo Fisher
Scientific representative installs the LCQ Fleet MS.
IMPORTANT If the instrument shipping container, ShockWatch, or other indicators show
any evidence of damage or mishandling during shipment, do NOT open the container.
Call your Thermo Fisher Scientific representative for instructions on what to do. If the
instrument arrives safely, proceed with the following instructions.
After you complete the laboratory site preparation and receive the LCQ Fleet instrument,
send the completed and signed “LCQ Fleet Installation Request Form” on page iii to your
local office for Thermo Fisher Scientific San Jose products. After receiving this form, the field
service engineer contacts you to schedule the installation.
Contents
• Installation Kits
• Customer-Supplied Hardware
• Basic On-Site Training
• Advanced Training Courses
• Preventive Maintenance
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
33
8
Installation
Installation Kits
Installation Kits
Your LCQ Fleet MS includes the following kits (Table 12).
Table 12. Kits provided with the LCQ Fleet MS
Kit name
Description
Part number
MS Setup Kit
Contains the installation components, such as
the exhaust and waste tubing, and the power
supply cords.
70111-62033
MS Accessory Kit
Special Accessory Kit
for the LCQ Fleet
Chemical Kit
Contains additional components, such as
fittings, fuses, tools, and tubing.
Contains the chemicals for demonstrating the
system performance specifications.
97055-62055
97055-62060
97355-62070
Customer-Supplied Hardware
Thermo Fisher Scientific does not provide all parts, materials, or tools that are required for
installation. To complete the installation, you must provide these additional parts (Table 13).
Table 13. Customer-supplied hardware for installation (Sheet 1 of 2)
Item
Description
(International destinations only)
230 Vac plug for the detachable
power supply cord
See “Power Supply Cords” on page 20.
Communications cable
Connects from the Ready Out and Start Out pins on
the instrument to a device not controlled by one of the
Thermo Scientific mass spectrometer applications,
such as the Xcalibur™ data system.
Refer to the LCQ Fleet Getting Connected Guide.
Gas line fitting, helium
Connects the 1/8 in. ID copper or stainless steel tubing
to the helium gas supply.
Refer to the LCQ Fleet Getting Connected Guide.
Gas line fitting, nitrogen
Connects the 1/4 in. OD Teflon™ PFA tubing to the
nitrogen gas supply.
Refer to the LCQ Fleet Getting Connected Guide.
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Thermo Scientific
8 Installation
Basic On-Site Training
Table 13. Customer-supplied hardware for installation (Sheet 2 of 2)
Item
LC system
LC system, solvents
Description
IMPORTANT If your system is manufactured by
another company, you must verify that it is suitable
for use with the LCQ Fleet MS. The output (start)
signal from the external device must be Normally Hi
(+5 Vdc) and momentarily go to Low. If you cannot
configure the external device to go from Normally Hi
to Low momentarily, you cannot use it with the
LCQ Fleet MS.
Used by the Thermo Fisher Scientific field service
engineer to calibrate the system during the initial
setup.
For details, refer to the appropriate manual.
(Optional) Compressed air line
fitting
Connection from the compressed air supply to the
optional FAIMS module (temperature control
module).
For details, refer to the FAIMS Operator’s Manual.
Basic On-Site Training
When your new LCQ Fleet system is on site and ready for installation, a Thermo Fisher
Scientific field service engineer unpacks and installs it.
During the installation, the field service engineer demonstrates the following:
• Basics of the instrument operation and routine maintenance
• Marketing specifications that are in effect when you purchased the system
Tip To receive maximum benefit from this on-site training opportunity, plan for the
system operators to be available during the entire installation process.
Do not use the new system for sample analysis until the installation is complete and you have
signed the Acceptance Form.
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
35
8
Installation
Advanced Training Courses
Advanced Training Courses
Thermo Fisher Scientific provides introductory and advanced training courses in analytical
techniques, in addition to specialized operation and maintenance courses for Thermo
Scientific products.
Thermo Fisher Scientific recommends that the key user receive advanced training for
operating and maintaining the LCQ Fleet system after using it for several months. After this
training from Thermo Fisher Scientific, the key user can conduct in-house training for other
staff members, certifying them to operate the system.
Preventive Maintenance
You are responsible for the routine and preventive maintenance of the LCQ Fleet system.
Regular preventive maintenance is essential. It increases the life of the system, maximizes the
uptime of the system, and provides optimum system performance. You can find maintenance
procedures in the following manuals:
• LCQ Fleet Hardware Manual
• Ion Max and Ion Max-S API Source Hardware Manual
• Manuals shipped with other devices for your system
36
LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
G
Glossary
A
B
C
D
E
F
G
H
I
J
K
L M N O
A
API source The sample interface between the liquid
chromatograph (LC) and the mass spectrometer
(MS).
atmospheric pressure chemical ionization (APCI) A
soft ionization technique done in an ion source
operating at atmospheric pressure. Electrons from a
corona discharge initiate the process by ionizing the
mobile phase vapor molecules, forming a reagent gas.
atmospheric pressure ionization (API) Ionization
performed at atmospheric pressure by using
atmospheric pressure chemical ionization (APCI),
electrospray ionization (ESI), or nanospray
ionization (NSI).
auxiliary gas The outer-coaxial gas (nitrogen) that
assists the sheath (inner-coaxial) gas in dispersing
and/or evaporating sample solution as the sample
solution exits the APCI, ESI, or HESI nozzle.
C
circuit breaker An electronic switch that
automatically shuts off power to its designated
circuits when there is a current overload or short
circuit condition. Multiple circuit breakers are
typically housed within one or more panels for a
given area. These devices must be certified for
compliance by a recognized organization for your
country.
Thermo Scientific
P
Q
R
S
T
U
V W X
Y
Z
collision energy The energy used when ions collide
with the collision gas.
collision gas A neutral gas used to undergo collisions
with ions.
computer data system See data system.
D
damping gas Helium gas introduced into the ion trap
mass analyzer that slows the motion of ions entering
the mass analyzer so that the ions can be trapped by
the rf voltage fields in the mass analyzer.
data system Consists of a computer, a monitor, a
keyboard, a mouse, an Ethernet switch, and an
optional printer.
E
electrospray (ESI) A type of atmospheric pressure
ionization that is currently the softest ionization
technique available to transform ions in solution into
ions in the gas phase.
electrospray ionization (ESI) See electrospray (ESI).
LCQ Fleet Preinstallation Requirements Guide
37
Glossary: FAIMS (high-Field Asymmetric waveform Ion Mobility Spectrometry)
F
FAIMS (high-Field Asymmetric waveform Ion
Mobility Spectrometry) An optional module for
separating ions at atmospheric pressure. FAIMS
provides ion separation by taking advantage of
compound-dependent changes in ion mobility at
high electric field strengths.
forepump The pump that evacuates the foreline. A
rotary-vane pump is a type of forepump. It might
also be referred to as a backing, mechanical, rotaryvane, roughing, or vacuum pump.
sweep gas Nitrogen gas that flows out from behind
the sweep cone in the API source. Sweep gas aids in
solvent declustering and adduct reduction.
syringe pump A device that delivers a solution from a
syringe at a specified rate.
U
UV-Vis detector Ultraviolet-visible spectroscopy. This
type of detector operates in the ultraviolet-visible
spectral region.
H
heated-electrospray (H-ESI) A type of atmospheric
pressure ionization that converts ions in solution into
ions in the gas phase by using electrospray (ESI) in
combination with heated auxiliary gas.
heated-electrospray ionization (H-ESI) See heatedelectrospray (H-ESI).
I
inrush current The initial current flowing through an
inductive load, such as a motor, when it is first
turned on. On average, the typical duration is less
than 100 ms.
N
nanoelectrospray (nanoESI or NSI) A type of
electrospray (ESI) that accommodates very low flow
rates of sample and solvent at 1–20 nL/min (for
static nanospray) or 100–1000 nL/min (for dynamic
nanospray).
S
sheath gas The inner coaxial gas (nitrogen), which is
used in the API source to help nebulize the sample
solution into a fine mist as the sample solution exits
the ESI or APCI nozzle.
source See API source.
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LCQ Fleet Preinstallation Requirements Guide
Thermo Scientific
I
Index
A
downloading documents xii
air conditioning system 13
API source drain 30
E
B
buck/boost transformer 17
C
circuit breakers 18
communications cables, Ethernet 5
compliance
FCC vi
regulatory v
compressed air 25
contacting us xiv
contaminants, gas 24
customer responsibility
damage due to contaminates 24
gases, solvents, and regulators 23
location and operating environment 1
power source 15
routine and preventative maintenance 36
waste and exhaust systems 29
D
data system
number of outlets 19
recommended layout 6
desiccant air dryer 25
dimensions
shipping containers 4
system modules 4
directive, WEEE vii
documentation
accessing xii
additional xi
Thermo Scientific
earth ground connections 18
electrical outlets 18–19
electromagnetic compatibility v
EMC compliance v
entrance requirements, building and lab 3
ESD precautions 13
Ethernet, communications cables 5
exhaust system 29
F
FAIMS, optional module
See compressed air
FCC compliance vi
floor vibrations 8
forepump
exhaust plumbing 8
exhaust requirements 29
placement 8
G
gases
compressed air 25
helium 24
nitrogen 24
ground
See earth ground connections
H
helium, supply requirements 24
humidity 12
LCQ Fleet Preinstallation Requirements Guide
39
Index: I
I
Installation Request Form iii
instrument damage through solvent contaminants 27
isolation/noise-suppression transformer 17
K
kits
Buck/Boost Transformer 17
Chemical 34
MS Accessory 34
MS Setup 34
Special Accessory 34
L
lamp, high-intensity 14
LC/MS system, number of outlets 19
line power
monitoring 16
requirements 15
liquid nitrogen
See nitrogen
load capacity
air conditioning 13
workbenches 5
M
maintenance, preventive 36
mass spectrometer, recommended layouts 7
N
nitrogen generator, daily consumption 25
nitrogen, supply requirements 24
O
outlets
See electrical outlets
P
particulate matter 13
plug types
Asia 22
Europe 21
North America 21
power
conditioning devices 17
electrical ratings 19
40
LCQ Fleet Preinstallation Requirements Guide
monitoring devices 16
quality of 16
power supply cords 20
R
regulatory compliance v
requirements
humidity 12
lab environment 11
particulate matter 13
temperature 12
rough pump
See forepump
S
safety standards v
service contract, exclusions 1
shipment, damage 33
ShockWatch, packaging 33
site preparation 3
solvent modifiers 26
solvents
contamination 27
recommendations 26
waste from 30
surge protector 18
system damage, gas contaminants 24
T
technical assistance 22
telephone 9
temperature 12
temperature and humidity monitor 12
Thermo Scientific website, user documents xii
training
advanced, scheduled classes 36
basic, on-site 35
transformer
buck/boost 17
isolation/noise-suppression 17
transient voltages 16–17
U
uninterruptible power supply (UPS) 17
UV-Vis detector 27
Thermo Scientific
Index: V
V
vacuum pump
See forepump
venting
forepump 29
solvent waste container 30
vibration, floor 8, 14
voltage, transient 16–17
W
warranty, limitations 1
WEEE directive vii
workbenches
module weights 4
surface dimensions 5
Thermo Scientific
LCQ Fleet Preinstallation Requirements Guide
41
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