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Medical
Applications
Guide
Consumer Medical
Diagnostic, Patient Monitoring and Therapy
Medical Imaging
Medical Instruments
Connectivity Solutions
Resources
www.ti.com/medical
2010
Medical Applications Guide
➔ Table of Contents
Disclaimer
TI products are not authorized for use
in safety-critical applications (such as
life support) where a failure of the TI
product would reasonably be expected
to cause severe personal injury or
death, unless TI and the customer have
executed an agreement specifically
governing such use. The customer
shall fully indemnify TI and its repre­sent­
atives against any damages arising out
of the unauthorized use of TI products
in such safety-critical applications. The
customer shall ensure that it has all
necessary expertise in the safety and
regulatory ramifications of its applications and the customer shall be solely
responsible for compliance with all legal,
regulatory and safety-related requirements concerning its products and any use of TI products in customer’s
applications, notwithstanding any
applications-related information or
support that may be provided by TI.
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Consumer Medical
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
Blood Pressure and Heart Rate/Fitness Monitoring Systems . . . . . . . . . . . . . 5
Blood Glucose and Other Diagnostic Meters . . . . . . . . . . . . . . . . . . . . . . . . . 6
Digital Thermometers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Consumer Medical General . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
System Support Products . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Power Management for Consumer Medical Devices . . . . . . . . . . . . . . . . . . 16
Component Recommendations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
Diagnostic, Patient Monitoring and Therapy
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Digital Stethoscopes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Patient Monitoring . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Electrocardiogram (ECG)/Portable ECG and
Electroencephalogram (EEG) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Pulse Oximeter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Ventilator . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Continuous Positive Airway Pressure (CPAP) . . . . . . . . . . . . . . . . . . . . . . . .
Dialysis Machine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Infusion Pump . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Automated External Defibrillator (AED) . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
23
23
29
34
44
53
61
67
70
74
Medical Imaging
TI’s Medical Applications
Guides available for
individual download:
• Consumer
Medical
• Diagnostic,
Patient
Monitoring and Therapy
• Medical
• Medical
Imaging
Instruments
Visit: www.ti.com/medicalguides
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
Ultrasound . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
Computed Tomography (CT) Scanners . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99
Magnetic Resonance Imaging (MRI) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105
Digital X-Ray . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112
Positron Emission Tomography (PET) Scanners . . . . . . . . . . . . . . . . . . . . . 118
Power Management for Medical Imaging . . . . . . . . . . . . . . . . . . . . . . . . . . 124
Medical Imaging Toolkit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126
Medical Instruments
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
DLP® Technology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Design Considerations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Component Recommendations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Endoscopes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
127
129
131
136
139
Connectivity Solutions for Medical
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Medical USB Platform . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Wired Solutions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Wireless Interface, RFID and Tag-it™ . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Low-Power RF Products . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
ZigBee® / Bluetooth® Low Energy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
141
142
143
144
147
148
Resources
Enhanced Products/Die and Wafer Sales Solutions . . . . . . . . . . . . . . . . . . 149
TI Design Tools . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150
TI Worldwide Technical Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152
Medical Applications Guide
2
Texas Instruments 2010
Medical Applications Guide
➔ Introduction
With its full range of analog and
embedded processing products, from
building blocks to complete semiconductor solutions, plus systems insight,
global support infrastructure, advanced
process technology and medical
industry involvement, TI is helping
make innovative medical electronics
more flexible, affordable and accessible.
Complete Portfolio
Commitment
• Amplifiers, data converters, interfaces,
power management, logic, DSPs,
ultra-low-power MCUs, ARM-based
MPUs, wired and wireless connectivity, audio and video ICs
• Catalog, application-specific,
enhanced and custom ICs, plus die
sales options
•Experience in supplying components
for a wide range of medical
applications
• Global support infrastructure
• Local technical support and
distribution
• Systems and applications insight
• Tools and training
TI’s experience in diverse markets such
as wireless communications, consumer
electronics, automotive and aerospace
enables engineers to meet increasing
needs for higher speeds, higher precision, lower power and smaller equipment while maintaining the high standards for quality and reliability that the
medical market demands.
Quality and Reliability
Why TI?
Innovative Semiconductor Solutions
• Making advanced medical devices
more flexible, affordable and
accessible
• Addressing growing needs for portability, wireless connectivity,
energy efficiency, performance and
precision
• State-of-the-art process technology
The Real
World
• Long product lifetimes and a robust
product obsolescence policy to ensure continuity of supply
• Ability to serve customers of all sizes
with a variety of needs
• Enhanced qualification and screening
available with enhanced package
offering
• Member of industry-standard organizations and alliances, such as
the Continua Health Alliance
• Robust process change control notification (PCN) and industry leading
product traceability
This latest guide makes it easier than
ever for you to explore TI’s IC solutions
for medical applications. We feature a
broad array of comprehensive system
block diagrams, selection tables and
key design tools to help you innovate
faster.
You will find solutions and support for
your medical applications design in the following segments, which are also
available at www.ti.com/medicalguides
for individual chapter download:
•Consumer medical
•Diagnostic, patient monitoring
and therapy
•Medical imaging
•Medical instruments
Data
Converter
Amplifier
Interface
Low-Power
RF
Temperature
Pressure
Position
Power
Management
Speed
Flow
Embedded
Processing
Humidity
Sound
Light
Identification
Data
Converter
Amplifier
Clocks &
Timing
Logic
Analog connects the digital and real worlds.
Medical Applications Guide
3
Texas Instruments 2010
Consumer Medical
➔
Overview
Five common system blocks are used
when designing everything from blood
glucose, digital blood pressure and
blood cholesterol meters to health
and fitness monitors such as digital
pulse/heart rate monitors and digital
thermometers. These blocks are:
the full range of high performance
analog solutions with instrumentation,
operational and buffer amplifiers, data
converters, power and battery management components, audio amplifiers,
and both wired and wireless interface
components.
The design goals for extended battery
life, high precision and fast response
times are driven by the user’s desire
to quickly know their health status. Additional requirements may drive the
need for more memory to allow for historical profiling, cabled or wireless interfaces for data upload or for access to
the sensor. Audio feedback for simple
good/not good indication or more complex step-by-step utilization instructions
may be required as well. Adding these
features without increasing power consumption is a significant challenge. • Power/battery management
• Control and data processing
• Sensor interface, amplification and
analog-to-digital conversion
• User interface and display
• Wireless connectivity (see chapter on connectivity solutions)
While all battery-operated, microcontroller-based handheld devices take
measurements using various bio-sensors,
the block implementation topology
differs greatly with the sensing, proc­
essing and information demands of the
meter type and feature set.
Connectivity for portable medical applications has become critical as consumers and caregivers are requiring data
to move from medical devices to data
hubs such as computers and mobile
phones. TI is a promoting member
of the Continua Health Alliance and
now offers the first
Continua-certified
USB platform for
Agent Devices. See page 142 for
more information.
TI can help you create the solutions. We offer a broad portfolio of processors,
ranging from the high performance
OMAP™ platform-based application
processors, to digital signal processors
(DSPs), ARM-based Sitara™ MPUs and ultra-low-power MSP430™
microcontrollers (MCUs) as well as
For more information on the Continua Health Alliance, visit http://www.continuaalliance.org.
For more information on TI’s offering
for Consumer Medical, please visit
www.ti.com/consumermedical
Core Portable Medical System (Processor, Memory, Display,
Keypad, Power, Battery Management)
LCD
Display
System Based and Optional
Functional Blocks in Portable Medical Systems
LCD
Backlight
Zigbee
Bluetooth
Bio Sensors
Precision
Reference
Instrumentation
nst
stru
rume
ment
ntat
atio
ion
AMP
Wireless Data
Transmission or
Sensor Access
Low Power Wireless
LCD
Controller
MSP430
Passive RF
Flash/EEProm
Buffer
AMP
ADC
USB
Controller
µController
Wired Data
Transmission
Transient
Protection
Clock
AFE Power
Keypad
µController
and
Memory Power
LED
Driver
Fuel
Gauge
Card Slot
For system
Calibration
Current Limit Switch
Lithium
Battery
Protection
Audio
Feedback or
Instructions
Battery
Charger
Battery Management
LEGEND
Plug
AC
Adapter
AC Line
(optional)
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact
your local TI sales office or distributor for system design specifics and product availability.
Portable medical meters system block diagram.
Medical Applications Guide
4
Texas Instruments 2010
Consumer Medical
➔ Blood Pressure and Heart Rate/Fitness Monitoring Systems
Blood Pressure Monitors
Sensor Interface — Allows the proc­es­
sor to control the cuff inflation/deflation
and sense blood pressure that is ampli­
fied by instrumentation amplifiers and
digitized by the ADC.
These monitoring systems use Korotkoff,
oscillometry or pulse transit time methods to measure blood pressure. A pressure cuff and pump, along with a
transducer, are used to measure blood
pressure and heart rate in three
phases: inflation, measurement
and deflation. Also included are
LCDs, selection buttons, memory recall, power manage­ment
and USB interface.
The core subsystems include:
Processor/Memory — Digital
pressure measurement and
heart rate are performed by the
microcontroller. Measure­ment
results are stored in flash memory as a data log that can be
uploaded to a computer via USB
or wireless connection.
User Interface — Allows the user
to control the pressure measure­
ment process and read the results on an LCD display.
LCD
Display
LCD
Controller
LCD CTLR
LEDs
Keypad
Air Pressure Controller
GPIO
GPIO
GPIO
Power Management — Converts input
power from the alkaline or rechargeable batteries to run various functional
blocks.
Audio
Amp
Timer
PWM or
DAC
Mono
Speaker
BP
Filter
FLASH/EEPROM
Microcontroller
Pressure
Pressure
Transducer
USB Port
Transient
Suppressor
USB
Interface
ADC
USB
LEGEND
Microcontroller Analog FE
Memory
Audio Amplifier
P/S
P/S
Battery
DC/DC
Boost
Converter
Linear
Regulator
(LDO)
Processor
LCD
P/S
LED
P/S
DC/DC
Boost
Converter
DC/DC
Boost
Converter
Interface
Amplifier
Logic
Power
ADC/DAC
Power Management
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a
reference. Please contact your local TI sales office or distributor for system design specifics and product availability.
Example application block diagram — blood pressure monitor.
Heart Rate/Fitness Monitors
Fitness monitors measure both a person’s amount and rate of exercise (e.g. miles and pace run) as well as effort
expended (e.g. through monitoring
heart rate). Typically, a wristwatch or
wrist-worn display is used for control
and providing feedback. Stored data
can be downloaded to a computer
via USB or a wireless USB dongle. All
parts of the system require ultra-lowpower embedded controllers and lowpower RF for communications. Heart
rate monitoring and exercise output
monitoring (e.g. running pace sensor or
power sensor) require additional signal
conditioning.
Note: “Heart Rate and EKG Monitor
using the MSP430FG439” (slaa280)
www-s.ti.com/sc/techlit/slaa280
Low-Power
RF
Input Signals
Heart
Signal
MSP430F2122
Amplifier
Bandpass
Filter
Amplifier
Digital Signal
Processing
NTC
Skin
Temperature
Thermistor
Coin-Cell
Battery
Heart rate monitor.
Or PC Dongle
Low-Power
RF
Coin-Cell
Battery
MSP430TM
Could be rechargeable cell
with more powermanagement content
Coin-Cell
Battery
Low-Power
RF
MSP430
Low-Power
RF
USB
USB
ADC
Accelerometer/
Transducer
Shoe/footstrike sensor.
Medical Applications Guide
OPA2333
5
Backlight
Driver
LCD
LCD Backlight
Wrist display/watch.
Texas Instruments 2010
Consumer Medical
➔ Blood Glucose and Other Diagnostic Meters
New innovations in diagnostic equipment are making it easier than ever to
test quickly for a number of critical
care assays in blood such as blood
gases, glucose, electrolytes, coagulation, chemistries, hematology and
cardiac markers (cTnl). With the advent
of new digital technologies, invasive
blood analyzers have become portable
and are used to measure the two major
assays of metabolic disorders in blood
system: glucose and cholesterol.
The two methods used for blood analyte measurement are the color
reflectance method and the amperometric method (electrochemical sensor
technology).
The analog front-end of the reflectance
method uses topical sensors (LED,
photo transistors) and a transimpedance
amplifier. Measurements made using
the color reflectance method are based
on reaction color intensity in
the reaction layer of the test strip by
reflectance photometry. The meter
quantifies the color change and generates a numerical value that represents
the concentration of cholesterol/glucose in blood.
Using the amperometric method, the
biosensor (test strip) is connected
directly to the transimpedance amplifier. Cholesterol/glucose present in
the blood, while undergoing chemical
reaction with the test strip, generates
charge and is measured by the amperometric method. An ambient temperature measurement is also necessary for
test strip characteristic compensation.
The measurement sequence is usually
controlled by a microcontroller (MCU). The MCU also processes the conversion results, storing the measurements
in an EEPROM or Flash memory and
controlling other functions such as the
keypad, real-time clock, sound/speech
Sensor Amplifiers
compression and serial communication
to a connected computer.
The audio output is provided by either a
PWM circuit or from the DAC. Both can
be used to generate beeping sounds
to signal when measurement results
are available. They also generate voice
instructions from the speech-synthesizer software using ADPCM compression algorithms. Measurement results
are stored with the measurement time
and date in the EEPROM or Flash memory as a data log that can be uploaded
to a computer via wireless interface.
See example block diagram on pg. 4.
Awarded for the True2go portable glucose
monitor by Home Diagnostics Inc.
LCD Module
Gain Block
Chemical
Sensors
Analog
MUX
RS232 Transceiver
Microcontroller
ADC
USB
Interface
Filter Block
Self Test& Bias
USB Port
Transient
Suppressor
USB
DAC
LEGEND
Processor
N Amplifiers
LED Backlight DSP/CPU Core
Supply
Supply
Battery
Battery
DC/DC
Boost
Converter
Interface
Amplifier
I/O Supply
DC/DC
Buck
Converter
LDO
Logic
Charger
Power
ADC/DAC
Power Management
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Portable blood gas analyzer block diagram.
Medical Applications Guide
6
Texas Instruments 2010
Consumer Medical
➔ Digital Thermometers
Digital Thermometers
Digital thermometers are quickly replacing traditional mercury thermometers
because they are fast, accurate and
effective, without the environmental
risk. With newer technologies, different
types of digital thermo­meters are classified based on the location where they
are used, such as oral, rectal, under­
arm, ear, etc. The ear thermometer
measures infrared eardrum heat, which
reflects hypothalamus temperature
— the temperature-controlling system
of the brain. Infrared sensors are used
in ear thermometers for ­measurement,
while thermopiles or thermistors may
be used in other ­thermometer types.
The block diagrams represent low-end
general-purpose and high-end digital
thermometers. Typical ADC resolution
used in general-purpose digital thermometers may be 12-bit and above
depending on the required accuracy
level. Good ADC reference is required
for better accuracy. A microcontroller
may be used for control purposes. Low-cost solutions employ a low-cost,
low-power microcontroller like the
MSP430, which has the integrated
Note: “Implementing an Ultra-LowPower Thermostat with Slope A/D
Conversion” (slaa129B)
www-s.ti.com/sc/techlit/slaa129b
Medical Applications Guide
Features like high-temperature alarm,
beep after measurement, auto shut-off
and a data log of previous temperatures are optional. Most thermometers
have easy-to-read displays, usually a
LCD display and low-battery indicator. Other peripherals include digital I/Os
and LCD drivers.
MSP430TM Microcontroller
Digital I/Os
Digital I/Os
T
High-end thermometers have a number
of thermopiles or thermistors whose
resistance changes with temperature. The resistance change is measured as
a change in voltage. This analog voltage is converted digitally by an analogto-digital converter (ADC). The ADC’s
speed and resolution depends on the
accuracy and time at which information is needed. If an ADC module is not available, it is
possible to digitize the analog signal
using a comparator and a timer for
slope analog-to-digital conversion. This method is generally used in lowcost digital thermometers. The single
slope conversion measures temperature. Capacitance, supply voltage and
frequency changes caused by aging or
temperature drift can be compensated
using a ratio­metric measurement
principle. comparator and timer needed to digitize the analog signal using the slope
analog-to-digital conversion technique.
Comparator
Keypad
Timer
Memory
LCD Control
(LCD Driver or I2C)
LCD
A general block diagram of a low-cost digital thermometer.
MSP430TM Microcontroller
Thermopile
or Thermistor
Digital I/Os
Op Amp
Keypad
Reference
Memory
LCD Control
(LCD Driver or I2C)
LCD
A general block diagram of a digital thermometer with high accuracy.
7
Texas Instruments 2010
Consumer Medical
➔ Consumer Medical General
Ultra-Low-Power PaLFI (Passive Low Frequency Interface)
TMS37157
Get samples and datasheets at: www.ti.com/sc/device/TMS37157
Key Features
• Wide supply voltage range 2V to 3.6V
• Ultra-low power consumption
• Active mode max. 150µA
• Power down mode 60nA
• Battery check and battery charge
function
• Resonance frequency: 134.2kHz
• Integrated resonance frequency
trimming
The PaLFI combines a low-frequency transponder with an SPI interface and power
management to a connected MSP430™ microcontroller. It is the ideal device for
any data logger, sensor or remote control application enabling operation without
the need of a battery.
Digital or Analog
Sensor
Applications
• Portable medical devices
• Implantable devices
• Measurement instruments
• Energy harvesting
MSP430TM
Energy
TMS3705
LF Base Station
134, 2 kHz
LF data
PaLFI
TMS37157
LF Transponder
with EEPROM
Base Station
Sensor System
PaLFI functional block diagram.
TMS37157
PaLFI – Passive Low Frequency Interface
Communication Interfaces
134.2kHz
Wired Communication Interface
3-wire SPI
Operating Voltage
2V to 3.6Vdc
Current Consumption
Active mode max: 150μA
Power down mode: 60nA
Battery Charge Current
Max: 2mA
Memory
Medical Applications Guide
SPI, RFID, direct microcontroller access via RFID
Operating Frequency
32-bit unique serial number
968-bit EEPROM user memory
8-bit selective address
Operating Temperature
–40°C to 85°C
Storage Temperature
–40°C to 125°C
Package
16-Pin VQFN (4mm × 4mm)
Packing/Delivery
Tape-on reel, 3000 per reel
8
Texas Instruments 2010
Consumer Medical
➔ Consumer Medical General
16-Bit, Ultra-Low-Power Microcontrollers
MSP430FG477, MSP430FG478, MSP430FG479
Get samples and datasheets at: www.ti.com/sc/device/PARTnumber (Replace PARTnumber with MSP430FG477,
MSP430FG478 or MSP430FG479)
View our video on MSP430TM 16-bit ultra-low-power MCU for portable medical devices at www.ti.com/430medical
Key Features
• Low supply-voltage range: 1.8V to 3.6V
• Ultra-low power consumption:
• Active mode: 280μA at 1MHz, 2.2V
• Standby mode: 1.1μA
• Off mode (RAM retention): 0.1μA
• Five power-saving modes
• Wakes up from standby mode in less than 6μs
• 16-bit RISC architecture
• 125ns instruction cycle
TI’s MSP430™ family of ultra-low-power microcontrollers consists of several
devices featuring different sets of peripherals targeted for various applications. The architecture, combined with five low-power modes, is optimized to achieve
extended battery life in portable measurement applications. The device features
a powerful 16-bit RISC CPU, 16-bit registers, and constant generators that contribute to maximum code efficiency. The digitally controlled oscillator (DCO) allows
wake-up from low-power modes to active mode in less than 6μs.
The MSP430FG47x is a microcontroller configuration with two 16-bit timers, a basic
timer with a real-time clock, a high performance 16-bit sigma-delta A/D converter,
dual 12-bit D/A/ converters, two configurable operational amplifiers, two universal
serial communication interface, 48 I/O pins, and a liquid crystal display driver with
contrast control.
Applications
• Portable medical meters, such as
blood glucose meters, pulse
oximeters
• Insulin pumps
• Digital thermometers
• Heart rate monitors
XIN/
XT2IN
XOUT/
XT2OUT
2
2
DVCC1/2
The MSP430FG47x is one of the SoC (System on Chip) series in the MSP430 portfolio. Because this device series has integrated the entire signal chain on-chip,
it greatly simplifies the design of medical devices. In addition to enabling more compact products, this device series also reduces BOM (Bill of Materials) costs
because of the need for fewer discrete components.
DVSS1/2
AVCC
A V SS
P1.x/P2.x
2x8
P3.x/P4.x
P5.x/P6.x
4x8
ACLK
Oscillators
FLL+
SMCLK
MCLK
Flash
RAM
60KB
48KB
32KB
2KB
2KB
2KB
CPU
64KB
MAB
Includes
16
Registers
MDB
EEM
Brownout
Protection
JTAG
Interface
SVS,
SVM
LCD_A
128
Segments
1,2,3,4
Mux
SD16_A
with
Buffer
1-Channel
SigmaDelta A/D
Converter
DAC12
12-Bit
2
Channels
Voltage
Out
OA0, OA1
2
Op Amps
Comparator
_A
Timer_B3
Watchdog
WDT+
15-Bit
Timer_A3
3 CC
Registers
Ports
P1/P2
2x8 I/O
Interrupt
Capability
Basic
Timer and
3 CC
RealRegisters,
Time
Shadow
Clock
Reg
Ports
P3/P4
P5/P6
4x8 I/O
USCI_A0:
UART/
LIN,
IrDA, SPI
USCI_B0:
SPI, I2C
RST/NMI
MSP430FG47x functional block diagram.
Medical Applications Guide
9
Texas Instruments 2010
Consumer Medical
➔ Consumer Medical General
16-Bit, Ultra-Low-Power Microcontrollers
MSP430F5418A, MSP430F5419A, MSP430F5435A, MSP430F5436A, MSP430F5437A, MSP430F5438A
Get samples and datasheets at: www.ti.com/sc/device/PARTnumber (Replace PARTnumber with MSP430F5418A,
MSP430F5419A, MSP430F5435A, MSP430F5436A, MSP430F5437A or MSP430F5438A)
Key Features
• Low supply-voltage range: 1.8V to 3.6V
• Ultra-low power consumption:
• Active mode: 230μA/MHz
• Standby mode (LPM3 RTC mode):
2.6µA
• Off mode (LPM4 RAM retention):
1.6µA
• Shutdown mode (LPM5): 0.1µA
• Wakes up from standby mode in less
than 5μs
• 16-bit RISC architecture:
• Extended memory
• Up to 25MHz system clock
The MSP430F541x and MSP430F543x series of microcontroller configurations
includes three 16-bit timers, a high-performance 12-bit ADC, up to four universal
serial communication interfaces, a hardware multiplier, DMA, a real-time clock
module with alarm capabilities, and up to 87 I/O pins. The architecture, combined
with five low-power modes, is optimized to achieve extended battery life in portable measurement applications.
These device series are ideally suited for portable medical and fitness applications. With up to 256kB flash and 16kB RAM, they are capable of hosting the application
as well as wireless protocols for medical devices with wireless capabilities. For
example, the BlueMSPTM platform, which is comprised of the MSP430F5438
Experimenter’s Board (MSP-EXP430F5438) and the BL6450 Bluetooth®
Connectivity Card, can use the MSP430F5438 to host the Bluetooth®
stack’s Health Device Profile.
Applications
• Portable medical meters
• Blood pressure monitors
• Patient sensor system
XIN
XT2IN
XT2OUT
DVCC
XOUT
Unified
Clock
System
ACLK
SMCLK
MCLK
DVSS
256KB
192KB
128KB
Flash
AVCC
AVSS
RST/NMI
Power
Management
16KB
RAM
LDO
SVM/SVS
Brownout
P1.x
SYS
Watchdog
PA
P2.x
I/O Ports
P1/P2
2x8 I/Os
Interrupt
Capability
PA
1x16 I/Os
P3.x
PB
P4.x
P5.x
PC
P6.x
PD
P7.x
P8.x
P9.x
PE
P10.x
PF
P11.x
I/O Ports
P3/P4
2x8 I/Os
I/O Ports
P5/P6
2x8 I/Os
I/O Ports
P7/P8
2x8 I/Os
I/O Ports
P9/P10
2x8 I/Os
I/O Ports
P11
1x3 I/Os
PB
1x16 I/Os
PC
1x16 I/Os
PD
1x16 I/Os
PE
1x16 I/Os
PF
1x3 I/Os
DMA
CPUXV2
and
Working
Registers
3 Channels
EEM
(L: 8+2)
USCI 0,1,2,3
JTAG/
SBW
Interface
Timer0_A5
MPY32
5 CC
Registers
Timer1_A3
3 CC
Registers
Timer_B7
7 CC
Registers
RTC_A
CRC16
Ax: UART,
IrDA, SPI
2
Bx: SPI, I C
ADC12_A
12-Bit
200kSPS
16 Channels
(12 ext/4 int)
Autoscan
MSP430F54xx functional block diagram.
Medical Applications Guide
10
Texas Instruments 2010
Consumer Medical
➔ Consumer Medical General
Low-Power Precision Instrumentation Amplifier
INA333
Get samples and datasheets at: www.ti.com/sc/device/INA333
Key Features
• Low offset voltage: 20µV (max)
• Low drift: 50nV/°C
• Low input bias current: 200pA (max)
—–
• Low noise: 50nV/√Hz
• Supply voltage: +1.8V to +5.5V
• Quiescent current: 50µA (max)
• EMI input filtered
• Packaging: MSOP-8, DFN-10
The INA333 is a low-power precision instrumentation amplifier offering excellent
accuracy. A single external resistor sets any gain from 1 to 1000 and provides the
industry-standard gain equation G = 1 + (100kΩ/RG). With three op amps, low
quiescent current, and operation with power supplies as low as +0.9V, it is ideal for
a wide range of portable applications.
V+
EMI
Input Filtered
–
VIN
A1
150kΩ
150kΩ
50kΩ
Applications
A3
RG
• Bridge amplifier
• Weigh scales
• Thermocouple amplifier
• RTD sensor amplifier
• Medical instruments
• Data acquisition
VO
50kΩ
A2
EMI
Input Filtered
+
VIN
Ref
150kΩ
G=1+
100kΩ
RG
150kΩ
V–
INA333 functional block diagram.
3.9µA, SC70-3, 30ppm/°C Drift Voltage References
REF3312, REF3318, REF3320, REF3325, REF3330, REF3333
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with REF3312, REF3318, REF3320, REF3325, REF3330, or REF3333)
Key Features
• Low power: Iq = 3.9µA (typ)
• High initial accuracy: 0.15% (max)
• Low dropout (25mV at 25°C and
1mA IOUT)
• Robust output current drive: ±5mA
• ±30ppm/°C temp drift (max)
• Extended industril temp range: -40°C to 125°C
The REF33xx is a low-power, precision, low-dropout
voltage reference family available in the tiny SC70-3
and SOT23-3 packages. Small size and low power
consumption (5μA max) make the REF33xx ideal for a wide
variety of portable applications.
DVCC
+3.3V
1.25
REF3318
1.8
REF3320
2.048
REF3325
2.5
REF3330
3.0
REF3333
3.3
REF3340
4.096
40k
+3.0V
+3.3V
AV CC
DVCC
A0+
INA159
100k
Voltage (V)
1µF
R1
66.5
V IN
+2.5V
AVCC
+3.0V
20k
Applications
• Blood glucose meter
• Digital stethoscope
• Portable ECG/EEG
C5
10µF
+3.0V
100k
REF3330
C4
Product
REF3312
16-Bit
ADC
C1
1.5nF
0.62V
A0
40k
MSP430x20x3RSA
+3.0V
REF3312
1.25V
C2
1µF
R2
R3
V REF
AVSS
DVSS
C3
1µF
Basic data acquisition system.
Medical Applications Guide
11
Texas Instruments 2010
Consumer Medical
➔ Consumer Medical General
1.8V, microPower CMOS Operational Amplifier Zerø-Drift Series
OPA333, OPA2333
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/OPA333
or www.ti.com/sc/device/OPA2333
Key Features
• Low offset voltage: 10µV (max)
• Zerø drift: 0.05µV/°C (max)
• 0.01Hz to 10Hz noise: 1.1µVPP
• Quiescent current: 17µA
• Supply voltage: 1.8V to 5.5V
• Rail-to-rail input/output
• Packaging: SC70, SOT23
• EMI input-filtered
Applications
4.096V
REF3140
+5V
+
0.1µF
R1
6.04kΩ
D1
R9
150kΩ
R5
31.6kΩ
+5V
0.1µF
-
R2
2.94kΩ
-
+ +
+
• Medical instruments
• Temperature measurements
• Battery-powered medical
instruments
• Electronic weigh scales
• Patient monitoring
The OPA333 series of CMOS operational amplifiers uses a proprietary auto-
calibration technique to simultaneously provide very low offset voltage (10µV max)
and near-zero drift over time and temperature. These miniature, high-precision,
low quiescent current amplifiers offer high-impedance inputs that have a commonmode range 100mV beyond the rails and rail-to-rail output that swings within
50mV of the rails. Single or dual supplies as low as +1.8V (±0.9V) and up to +5.5V
(±2.75V) may be used. The OPA333 family offers excellent CMRR without the
crossover associated with traditional complementary input stages. This design
results in superior performance for driving analog-to-digital converters (ADCs)
without degradation of differential linearity.
R2
549Ω
OPA333
R6
200Ω
K-Type
Thermocouple
40.7µV/°C
R4
6.04kΩ
R3
60.4Ω
VO
Zero Adj.
OPA333 in temperature measurement circuit.
Medical Applications Guide
12
Texas Instruments 2010
Consumer Medical
➔ System Support Products
Voltage Level Translation
Applications
As operating voltage levels in microcontrollers continue to drop, a void that disrupts
device interfacing may be created between peripheral devices and processors. TI’s
translators enable communication between incompatible I/Os with level translation
between the 1.2V, 1.5V, 1.8V, 2.5V and 3V nodes. The MSP430TM microcontroller
has a 3.6V (max) I/O tolerance, allowing translators to be used to protect the
inputs and interface to higher voltage peripherals.
• LCD interface
• Interface devices with different supply voltages
Suggested Components
VCC
Range
(V)
Power
Max ICC
(µA)
Smallest
Footprint
Pins/Packages
Component
Description
SN74AVC1T45*
Single-bit Dual-Supply
Bus Transceiver
1.2 to 3.6
10
6/WCSP
(NanoStar™)
SN74LVC1T45
Single-bit Dual-Supply
Bus Transceiver
1.65 to
5.5
4
6/WCSP
(NanoStar)
SN74AVC2T45*
Dual-bit Dual-Supply
Transceiver
1.2 to 3.6
10
8/WCSP
(NanoStar)
SN74LVC2T45
Dual-bit Dual-Supply
Transceiver
1.65 to
5.5
10
8/WCSP
(NanoStar)
SN74AUP1T57
Single-Supply Voltage
Translator
2.3 to 3.6
0.9
6/WCSP
(NanoStar)
SN74AUP1T58
Single-Supply Voltage
Translator
2.3 to 3.6
0.9
6/WCSP
(NanoStar)
SN74AUP1T97
Single-Supply Voltage
Translator
2.3 to 3.6
0.9
6/WCSP
(NanoStar)
SN74AUP1T98
Single-Supply Voltage
Translator
2.3 to 3.6
0.9
6/WCSP
(NanoStar)
PCA9306
Dual Bidirectional
I2C-bus and SMBus
—
—
8/US
1.8 V
3.3 V
Level
Translator
1.8V CPU
VCCA
DIR
A1
A2
A3
A4
A5
A6
A7
A8
GND
GND
VCCB
VCCB
OE
B1
B2
B3
B4
B5
B6
B7
B8
GND
3.3V
Peripheral
Example application block diagram.
Voltage-Level
Translator
*Bus-hold option available.
Audio Signal Routing
Applications
One of the most common applications for analog switches is signal routing. Routing may come from one source to multi­ple destinations or from several
sources to a single destination. A single-pole, double-throw analog switch can
be used for either situation. The switch could be used to reroute the output of the
audio power amplifier to two different speakers. Another common application is
switching from an audio amplifier in the baseband of a mobile handset to an audio
power amplifier for higher power output.
• DeMUX internal/external speakers
• MUX audio power amplifier
• Low-power routing (<100mA)
• Amplifier gain adjustment
Suggested Components
Component
Configuration
V+
(V)
ron
(Ω)
Smallest Footprint
Pins/Packages
TS5A3159A
1 x SPDT
1.65 to 5.5
0.9
6/WCSP
TS5A3166
1 x SPST
1.65 to 5.5
0.9
6/WCSP
TS5A23166
2 x SPST
1.65 to 5.5
0.9
6/WCSP
TS5A3153
1 x SPDT
1.65 to 5.5
0.9
8/WCSP
TS5A6542
1 x SPDT
1.65 to 5.5
0.75
8/WCSP
TS5A23159
2 x SPDT
1.65 to 5.5
0.9
10/Micro QFN
TS5A26542
2 x SPDT
1.65 to 5.5
0.75
12/WCSP
TS5A3359
1 x SP3T
1.65 to 5.5
0.9
8/WCSP
Medical Applications Guide
External
TS5A3159A
16 to 32Ω
Audio
Power
Amp
8Ω
Internal
Example application block diagram.
13
Texas Instruments 2010
Consumer Medical
➔ System Support Products
I2C Bus I/O Expansion and LED Drivers
Benfits
• Processor pin savings
• Improved board routing
• Reduced board space
Applications
I2C I/O expanders and LED drivers supplement application functionality. They free
the processor from less critical functions and serve to create a more efficient design. Often there are not enough GPIOs available on the microcontroller to control all
of the desired peripherals, such as interfacing to a keypad. An I2C bus expander can
increase the number of GPIOs in the application while taking up minimal board
space. I2C LED drivers free the processor from LED blink operations.
• Keypad control
• LED control
• Temperature sensing
Optional
Pressure Sensor
1. Silicon Pressure
2. Load Cell
RS-232
Op Amp
LPV324
VREF
TLV431B
3.0V
I 2 C Bus
IrDA
Keypad
Microcontroller
with Integrated
12-/16-Bit ADC
and LCD Driver
EEPROM
LCD Display
2.5V
Power Management
Charge Pump
Switching Regulator
Power Management
LDO Regulator
3.3V
DC Motor
Example application block diagram.
Suggested Components
Device
Max freq. (kHz)
No. of I/Os
I2C address
VCC range (V)
Low–Voltage I/O Expanders
TCA6408A
400
8
0100 00x
1.65 to 5.5
TCA6416A
400
16
0100 00x
1.65 to 5.5
TCA6424
400
24
0100 00x
1.65 to 5.5
TCA9535
400
16
0100 xxx 1.65 to 5.5 TCA9539
400
16
1110 1xx 1.65 to 5.5 TCA9555
400
16
0100 xxx 1.65 to 5.5 PCA6107
400
8
0011 xxx
2.3 to 5.5
PCA9534
400
8
0100 xxx 2.3 to 5.5 PCA9534A
400
8
0111 xxx 2.3 to 5.5 PCA9535
400
16
0100 xxx 2.3 to 5.5 PCA9536
400
4
1000 001 2.3 to 5.5 PCA9538
400
8
1110 0xx 2.3 to 5.5 PCA9539
400
16
1110 1xx 2.3 to 5.5 PCA9554
400
8
0100 xxx 2.3 to 5.5 PCA9554A
400
8
0111 xxx 2.3 to 5.5 PCA9555
400
16
0100 xxx 2.3 to 5.5 PCA9557
400
8
0011 xxx 2.3 to 5.5 PCF8574
100
8
0100 xxx 2.5 to 6.0 PCF8574A
100
8
0111 xxx 2.5 to 6.0 PCF8575
400
16
0100 xxx 2.5 to 5.5 PCF8575C
400
16
0100 xxx 4.5 to 5.5 400
7
1000 101 1.65 to 3.6 18
110100
1.65 to 3.6 I/O Expanders
LED Driver
TCA6507
Keypad / Keyboard Controller
TCA8418
Medical Applications Guide
1000
14
Texas Instruments 2010
Consumer Medical
➔ System Support Products
System-Level ESD/EMI Protection for High-Speed Applications
Benefits
• System-level ESD protection for
high-speed interconnects
• Space-saving package and flowthrough layout enable glitch-free
layout for the high-speed portable
applications
• Ultra-low 1nA leakage current
enables precision analog measure­
ments like those of glucose meters
• The optional VCC pin allows the
device to work as a transient
suppressor
For any external interface connector port, an ESD strike is a constant threat to system reliability. Many low-voltage core chip or system ASICs offer only devicelevel human-body model (HBM) ESD protection, which does not address systemlevel ESD. A stand-alone ESD solution is a space- and cost-effective solution to
protect the system interconnects from external ESD strikes.
TI’s TPDxE series ESD devices provide an IEC-61000-4-2 (Level 4) system-level
ESD solution while maintaining signal integrity at the high-speed interfaces. The
TPDxF series EMI filter provides immunity against conducted EMI noise while providing system-level ESD protection.
TPD2E009
Applications
TPD2E009
I/O 1
• USB, HDMI, DisplayPort, eSATA,
GigEthernet, 1394, Interface
• Analog precision interface
Protected
Circuit
I/O 1
I/O 1
I/O 2
I/O 2
I/O 2
TPD2E009 ESD circuit and board layout.
ESD/EMI Solutions
Device
Number of Channels
VDD (V)
I/O Level (V)
Cap, Resistor
VBR (min) (V)
Package(s)
ESD Solutions
TPD2E009
2-Channel ESD
0.9 to 5.5/No VDD pin
0 to VDD
0.7pF
6
DRY, DRT, DBZ
TPD4S009
4-Channel ESD
0.9 to 5.5
0 to 5.5
0.8pF
9
DRY, DCK, DBV
TPD4S010
4-Channel ESD
No VDD pin
0 to 5.5
0.8pF
9
QFN
TPD8S009
8-Channel ESD
0.9 to 5.5
0 to 5.5
0.8pF
9
DSM
TPD12S520
12-Channel, HDMI Receiver
0.9 to 5.5
0 to 5.5
0.9pF
9
DBT
TPD12S521
12-Channel, HDMI Driver
0.9 to 5.5
0 to 5.5
0.9pF
9
DBT
TPD4S012
4-Channel ESD with VBUS Clamp
No VDD pin
0 to 5.5
1.0pF, 9pF
7, 20
DRY
TPD2E001
2-Channel ESD
0.9 to 5.5
0 to VDD
1.5pF
11
DRL, DRY, DRS
TPD3E001
3-Channel ESD
0.9 to 5.5
0 to VDD
1.5pF
11
DRL, DRY, DRS
TPD4E001
4-Channel ESD
0.9 to 5.5
0 to VDD
1.5pF
11
DRL, DRS
TPD6E001
6-Channel ESD
0.9 to 5.5
0 to VDD
1.5pF
11
RSE, RSF
TPD6E004
6-Channel ESD
0.9 to 5.5
0 to VDD
1.6pF
6
RSE
TPD4E004
4-Channel ESD
0.9 to 5.5
0 to VDD
1.6pF
6
DRY
TPD4E002
4-Channel ESD
No VDD pin
0 to 6
11pF
6
DRL
TPD6F002
6-Channel EMI
0.9 to 5.5
0 to 5.5
17pF, 100Ω, 17pF
6
DSV
TPD6F003
6-Channel EMI
0.9 to 5.5
0 to 5.5
8.5pF, 100Ω, 8.5pF
6
DSV
EMI Filters
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
15
Texas Instruments 2010
Consumer Medical
➔ Power Management for Consumer Medical
Low-IQ LDO with Dual-Level Outputs
TPS78001
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/TPS78001
Key Features
• Rated output current: 150mA
• Ultra-low IQ: 500nA typ (TPS780xx)
• Input-voltage range: 2.2V to 5.5V
• Output voltages: Fixed (1.5V to 4.2V)
and adjustable (1.22V to 5.25V)
• VSET pin allows VOUT to toggle
between two factory EEPROM preset values
• Stable with 1μF ceramic output
capacitor
• Packaging: TSOT23-5, 2 x 2mm
SON
The TPS780xx family of low-dropout (LDO) regulators offers the benefits of ultralow power (IQ = 500nA), miniaturized packaging (2 x 2mm SON-6), and selectable
dual-level output-voltage levels. An adjustable version is also available but does
not have the capability to shift voltage levels.
The VSET pin allows the end user to switch between two voltage levels on the fly
through a microprocessor-compatible input. This LDO is designed specifically for
battery-powered applications where dual-level voltages are needed. With ultra-low
IQ (500nA), this device is ideal for applications such as microprocessors, memory
cards and smoke detectors.
VIN
1µF
VOUT
TPS780xx
Applications
• TI MSP430™ attach applications
• Wireless handsets
• Portable media players
GND
2.2V to 3.3V
VCC
MSP430
or
Equivalent
1µF
VSET
I/O
VSS
TPS780xx with integrated dynamic voltage scaling.
0.7VIN Boost Converter with 5μA IQ
TPS61220
Get samples and datasheets at: www.ti.com/sc/device/TPS61220
Key Features
• Extended battery run time due to
extreme low quiescent current of
<5µA
• Ideal for low-current applications
due to low switch-current limit
• Works well with low-power microcontrollers like TI’s MSP430™ family
• Switching frequency: 2MHz
• Packaging: SC-70
TI’s TPS6122x boost converters manage the power conversion to applications
powered by a single-cell, two-cell, or three-cell alkaline, NiCd or NiMH, or one-cell
Li-Ion or Li-Polymer battery. The devices provide an output current up to 50mA at
a 5V output while using a single-cell Li-Ion or Li-Polymer battery, and discharge it
down to 2.5V. The TPS6122x family is based on a hysteretic, fixed off-time controller using synchronous rectification to obtain maximum efficiency at the lowest
possible quiescent current level. Maximum input current is limited to a value of 250mA. Output voltage can be programmed by an external resistor divider or can
be fixed internally on the chip. The TPS6122x converters are available in a 6-pin, 2 x 2mm SC-70 package.
Applications
• Microcontroller power supply
• Any portable application
TPS61220
L1
2.2µH
0.7V
to VOUT
L
VIN
C1
4.7µF
EN
VOUT
FB
R1
R2
VOUT
1.8V to 5.5V
C2
4.7µF
GND
TPS61220 boost converter with low IQ.
Medical Applications Guide
16
Texas Instruments 2010
Consumer Medical
➔ Power Management for Consumer Medical
White LED Driver with Digital and PWM Brightness Control
TPS61160, TPS61161
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/TPS61160
or www.ti.com/sc/device/TPS61161
Key Features
• 2.7 to 18V input-voltage range
• 26V open LED protection for 6 LEDs
(TPS61160)
• 38V open LED protection for 10 LEDs
(TPS61161)
• 0.7A switch current-limit protection
• 600kHz switching frequency
• 200mV ref voltage with 2% accuracy
• EasyScale™ one-wire dimming
interface
• PWM brightness control (5 to 100kHz)
• Built-in soft start
• Packaging: 2 x 2 x 0.8mm QFN-6
With a 40-V rated integrated switch FET, the TPS61160 and TPS61161 are boost
converters that drive up to 10 LEDs in series. The boost converters run at 600kHz
fixed switching frequency to reduce output ripple, improve conversion efficiency
and allow for the use of small external components.
L1
2.2µH
VIN 3 to 18V
C1
1.0µF
D1
C2
1.0µF
TPS61161
VIN
On/Off
Dimming
Control
C3
220nF
SW
CTRL
FB
COMP
GND
RSET
10 Ω
Applications
• 2.5 to 4.0" displays
• PDAs, cell phones, handheld computers
• GPS receivers
• General white LED backlighting for
media form-factor displays
Typical application.
20mA
USB-Compliant Li-Ion Charger in 2mm x 2mm QFN
bq24040
Get samples and datasheets at: www.ti.com/sc/device/bq24040
Key Features
• 30-V input rating and 6.6-V overvoltage protection
• Integrated 800-mA FET and current sensor
• USB compliance: USB current limiting and input voltage dynamic
power management
• JEITA compliance: reduced charge current at cold and reduced charge voltage at hot
• Packaging: small 10-lead, 2-mm x 2-mm QFN
Applications
• Portable devices powered by 1-cell
Li-Ion or Li-Pol batteries
The bq24040 operates from either a USB port or AC adapter. The 100mA /500mA
current limit in USB mode fully complies with USB standard. The Input Dynamic
Power Management feature reduces the charge current when the input voltage
drops to an internal threshold, protecting the source from excessive loads. In
addition, the bq24040 comes with more safety features: JEITA compliance, overvoltage protection, safety timers, and ISET short protection.
1.5kΩ
bq24040
Adaptor
1 IN
DC+
GND
1µF
1kΩ
OR
2kΩ
OUT 10
2 ISET
TS 9
3 VSS
CHG 8
4 PRETERM ISET2 7
5 PG
NC 6
1.5kΩ
System Load
Battery Pack
+
1µF
VDD
TTDM/BAT_EN
USB Port
VBUS
GND
D+
D-
ISET/100/500mA
GND
D+
Host
D-
Functional block diagram.
Medical Applications Guide
17
Texas Instruments 2010
Consumer Medical
➔ Power Management for Consumer Medical
Pack-Side Impedance Track™ Fuel Gauge
bq27541
Get samples and application reports at: www.ti.com/sc/device/bq27541
Key Features
• Battery fuel gauge for 1-series Li-Ion
applications
• Microcontroller peripheral provides:
• Accurate battery fuel gauging
• Internal temperature sensor for
system temperature reporting
• SHA-1/HMAC authentication
• 96 bytes of nonvolatile scratch
pad flash
• Battery fuel gauging based on patented Impedance Track™ technology
• Models battery-discharge curve for
accurate time-to-empty predictions
• Automatically adjusts for battery
aging, battery self-discharge and
temperature/rate inefficiencies
• Low-value sense resistor
(10mΩ or less)
• SDQ, HDQ and I2C interface
formats for communication with host system
• Packaging: Small 12-pin, 2.5 x 4mm
SON
Applications
• Smartphones
• PDAs
• Digital still and video cameras
• Handheld terminals
• MP3 or multimedia players
Medical Applications Guide
TI’s bq27541 Li-Ion battery fuel gauge is a microcontroller peripheral that provides
fuel gauging for single-cell Li-Ion battery packs. The device requires little system microcontroller firmware development for accurate battery fuel gauging. The
bq27541 resides within the battery pack or on the system’s main board with an embedded (nonremovable) battery.
The bq27541 uses the patented Impedance Track™ algorithm for fuel gauging and
provides information such as remaining battery capacity (mAh), state-of-charge
(percent), run time to empty (min), battery voltage (mV) and temperature (°C).
The bq27541 also features integrated support for secure battery-pack authentication using the SHA-1/HMAC authentication algorithm.
PACK +
SDQ/HDQ
Multiple
Communication
Methods
SDA
SCL
Single-Cell
Protector
bq27541 Impedance
Track™, AFE,
Manufacturing Data
Storage, and
Authentication
°T
PACK –
Typical application.
18
Texas Instruments 2010
Consumer Medical
➔ Component Recommendations
Amplifiers
INA118
INA122
Component
Instrumentation Amp
Instrumentation Amp
Key Features
—
55µV offset, 0.7µV/°C drift, 10nV/√(Hz) noise
±50µV (max) input offset, 83dB CMRR, 0.06mA (typ) IQ
INA333 *Page 11
Instrumentation Amp
25μV (max) offset, 50nV/°C drift, 50μA (typ) Iq
OPA141
Precision Op Amp
OPA333/2333
*Page 12
OPA364
Precision Op Amp
OPA369
Nanopower ZeroCrossover Op Amp
Low Noise Precision
Op Amp
Low-Power
High-Speed Amp
Very Low-Power
Differential Amp
microPower Op Amp
Analog-Input
Class-D Amp
10MHz, 6.5nV/√Hz, ±4.5V to ±18V, 1.8mA typical, FET
input: IB = 20pA max
1.8V min supply, 0.017mA/ch (max), 10μV offset
(max), 0.05 μV/°C drift (max)
1.8V, 7MHz, 90dB CMRR, 5V/µs slew rate,
750µA/ch IQ
1.8V to 5.5V, 700nA IQ, CMRR 114dB RRIO, 0.4µV/°C,
Vos drift
0.1µV/°C Vos drift, 125µA, 900kHz, 0.4μVPP (0.1Hz to
10Hz) 0.4µ Vpp (0.1Hz to 10Hz), 0.9MHz
Typical quiescent current of 460µA/channel
OPA378
OPA2889
THS4524
TLV276x
TPA2011D1
TPA2013D1
Description
CMOS Amplifier
SAR and ΔΣ drivers, 145MHZ, 490V/µs slew rate
1.8V, RRIO, 500µV input offset voltage, 500kHz BW
Variable gain, 3.2W mono Class-D with integrated DAC
noise filter in 0.4mm pitch WCSP
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp with
AGC/DRC
Analog-Input
Class-D Amp with
AGC/DRC
Class-AB Audio Amp
Class-AB Audio Amp
2.7W constant output power, mono, Class D,
integrated boost converter
3.2-W/channel, stereo Class-D audio amplifier with fast
gain ramp, SmartGainTM AGC and DRC
ADS1115
Delta-Sigma ADC, I2C
ADS7866
ADS7924
SAR ADC, Serial
microPower SAR ADC
ADS8201
Low-Power SAR ADC
ADS8317
ADS8326
ADS8331/32
SAR ADC, Serial
SAR ADC, Serial
SAR ADC
16-bit, 860SPS, 4 SE, 2 diff input, PGA, MUX,
comparator, VREF
1.2V, 12-bit, 200kSPS (max), 85dB SFDR
12-bit, 100kSPS, 4 channel, ≤1µA power down
current, I2C interface, QFN package
8 channel, 12-bit, 100kSPS, 1.32mW power
consumption at 100kSPS
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
16-bit, 500kSPS, 4/8 channels, with serial interface
DAC7551
DAC8534
DAC8554
DAC8551
VOUT DAC
VOUT DAC
Low-Power DAC
VOUT DAC
12-bit, 500kSPS, ±0.5LSB DNL, ±1LSB INL, 0.27mW power
16-bit, 0.093MSPS, ±1LSB DNL, ±64LSB INL, 2.7mW power
16-bit, 1-4 chs, ±3 LSB (typ) INL, 0.1 to 0.15nV-s glitch
16-bit, 140µA at 2.7V operation, 0.1nV-s glitch energy
DAC8560
DACx311
VOUT DAC
Low-Power DAC
TLV320DAC3120
Low-Power Audio DAC
16-bit, 2ppm/°C temp drift, 2.5V int reference
14-and 16-bit, 1.8V to 5.5V, 80mA, 14- and 16-bit,
low-power, single-channel in SC70 package
Mono DAC with 2.5W mono Class-D speaker amplifier;
miniDSP for audio processing
TPA2026D2
TPA2028D1
TPA6205A1
TPA6211A1
3.0-W mono Class-D audio amplifier with fast gain ramp,
SmartGainTM AGC and DRC
1.25W mono, fully differential, Class AB, 1.8V shutdown
3.1W mono, fully differential, Class AB
Benefits
Other TI Solutions
Low drift, low noise, wide supply
Low power, wide supply, CM to Gnd
INA128, INA326, INA333
INA122: INA121,
INA126, INA128
INA321, INA326, INA118
Best offset/noise combination, supply down to
1.8V, low power
Common mode voltage range includes GND
OPA827
Zero drift, high precision, low power, EMI input
Sensor amplification in battery-powered systems
Zero-crossover input offers excellent CMRR over
entire input range
Lowest noise, power, price, precision zero-drift
option
Supports portable and power-sensitive
applications
Accurate output common-mode
Available in S, D, Q, 20µA/ch IQ
The TPA2011D1 Class-D speaker amplifier is
smaller, has fewer external components, consumes
less power and has no pop
Louder audio at low battery levels
OPA335, OPA378,
OPA330
OPA363, OPA2363,
OPA2364, OPA4364
OPA379, OPA349
OPA330, OPA333
OPAx890, OPAx684,
OPAx683, THS4281
TPA2010D1
TPA2014D1
Provides louder and clearer audio while protecting
speakers using DRC and AGC compared to
competitive products using just the AGC limiter option
Provides louder and clearer audio while protecting
speakers using DRC and AGC compared to competitive
products using just the AGC limiter option
Loud audio, low cost
Loud audio
TPA2016D2,
TPA2017D2
Smallest 16-bit ADC, 2.0 x 1.5 x .04 mm leadless
WFN pkg; reduces system size/component count
Very small, low power
Intelleigent system power management and self
monitoring
Full on-chip data acquisition system
ADS1113/4,
ADS1013/14/15
ADS7888
TPA751
Data Converters
ADS7870
Excellent linearity, microPower, high speed
Low noise, low power, high speed
Mux out feature can be used to reduce system
part count and overall cost
Ultra-low glitch
Quad
Excellent AC/DC performance
Very low power, ultra-low glitch
ADS8422
ADS8325
ADS8342
Tiny package, single channel
Easy resolution upgrade and downgrade capability;
decrease board space and power requirements
Longer battery life, better audio quality, lower cost
DAC8564, DAC8565
DAC7554
DAC8564, DAC8534
DAC8531
TLV320AIC3104,
TLV320AIC3120
References
REF29xx
REF30xx
Low-Power, Low-Cost
Series Reference
Low-Power, Low-Drift
Series Reference
50µA, 2% initial accuracy, 100ppm/°C max drift,
±25mA output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
50µA, 0.2% initial accuracy, 50ppm/°C max drift,
±25mA output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
New products are listed in bold red. Preview products are listed in bold blue.
*For additional product information see designated page number
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
REF30xx, REF31xx,
REF33xx
REF31xx, REF33xx,
REF29xx
19
Texas Instruments 2010
Consumer Medical
➔ Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
References (Continued)
REF31xx
Voltage Reference
REF32xx
Ultra-Low-Drift Series
Reference
Very-Low-Power
Series Reference
Precision Reference
REF33xx
*Page 11
REF50xx
15ppm/°C (max) drift, 5mV low dropout, 115µA (max)
IQ, 0.2% (max) accuracy, 1.25V, 2.048V, 2.5V, 3.0V,
3.3V, 4.096V
100µA, 0.2% initial accuracy, 7ppm/°C max drift,
±10mA output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
No load capacitor required
REF32xx, REF33xx
5µA, 0.15% initial accuracy, 30ppm/°C max drift,
±5mA output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V, 3.3V
0.05% accuracy, 3ppm/°C (max) drift, 3µVPP/V low
noise, 2.048V, 2.5V, 3.0V, 4.096V, 4.5V, 5V, 10V
Preserves battery life, fits into physically
constrained systems
Outstanding accuracy
REF30xx, REF31xx,
REF29xx
REF02, REF102
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
1KB/2KB Flash, 128B RAM, SPI+I2C
High performance at handheld power levels
8 ch. 12-bit ADC or 4 ch. 16-bit SD ADC,
4 x 4mm package
12 ch. 10-bit ADC, 2 op.amps
AM3505
Improves system accuracy
Processors
AM3517
MSP430F20xx
Applications Processor
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 512B/1KB RAM, SPI + I2C +
UART/LIN + IrDA
8 to 32KB Flash, 1KB/2KB RAM, SPI + I2C +
UART/LIN + IrDA
32 to 120KB Flash, 2 to 8KB RAM, SPI + I2C + UART,
DMA, SVS
92 to 120KB Flash, 4KB/8KB RAM, SPI + I2C + UART,
DMA, SVS
4 to 32KB Flash, 256B to 1KB RAM, SVS,
96 segment LCD
8 to 32KB Flash, 256B to 1KB RAM, SPI + UART, SVS,
128 segment LCD
16 to 32KB Flash, 256B RAM, 56 segment LCD,
2 op amps
16 to 32KB Flash, 256B RAM, 56 segment LCD
2 op amps
16 to 32KB Flash, 512B/1KB RAM, SPI + UART, SVS,
160 segment LCD
32 to 60KB Flash, 1KB/2KB RAM, SPI + UART, SVS,
128 segment LCD, 3 op amps
32 to 60KB Flash, 1KB/2KB RAM, 2x SPI + UART, SVS,
160 segment LCD
92 to 120KB Flash, 4KB/8KB RAM, SPI + I2C +
UART/LIN + IrDA, 160 LCD, 3 op amps
MSP430FG47x
*Page 9
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 2KB RAM, 16-bit DS A/D, 12-bit
D/A, op amp, 128Seg LCD
MSP430F54xxA
*Page 10
MSP430F552x
Ultra-Low-Power
16-Bit MCU
Applications
Processor
Low-Power
Applications
Processor
128 to 256KB Flash, 16KB RAM, (4) USCI, PMM, DMA,
temp. sensor
Up to 128KB Flash, 8+2KB RAM, USB, SPI + I2C
MSP430F22x4
MSP430F23x0
MSP430F24xx
MSP430F26xx
MSP430F41x
MSP430F42x
MSP430F42x0
MSP430FG42x0
MSP430F43x
MSP430FG43x
MSP430F44x
MSP430FG461x
OMAP-L137
TMS320C5000™
DSP
TMS320F2802x/3x
Piccolo
32-Bit Microcontroller
TMS320F283x
Delfino
32-Bit Floating-point
Microcontroller
TMS320VC5506
DSP
Analog comparator, HW multiplier
8 ch. 12-bit ADC, 2 ch.12-bit DAC, analog comp,
HW multiplier
8 ch. 12-bit ADC, 2 ch.12-bit DAC, analog comp,
HW multiplier
Analog comparator
3 x 16-bit SD ADC
5 ch. 16-bit SD ADC, 12-bit DAC
5 ch. 16-bit SD ADC, 12-bit DAC
8 ch. 12-bit ADC, analog comparator
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, DMA,
3 op amps
8 ch. 12-bit ADC, HW multiplier
12 ch.12-bit ADC, 2 ch.12-bit DAC, A-comp,
3 op amp, HW multiplier
Two 16-bit timers, a basic timer with a real-time
clock, a high performance 16-bit DS ADC, dual
12-bit DACs, two configurable op amps
16 ch. 12-bit ADC, analog comparator, RTC,
internal voltage regulator for power optimization
Integrated USB, 12-bit ADC
300MHz ARM9™ w/MMU + 300MHz C674x™
floating-point DSP core, rich peripheral set including
10/100 Ethernet MAC, LCD controller, USB 2.0 HS
OTG, USB 1.1 full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system
cost and maximum flexibility for connectivity, GUI and
high-level OS options. Extends product battery life by
providing greater than 60% power reduction over existing
solutions in the market.
Power efficient, high performance
Fixed-point DSP with industry’s best combination
of standby and dynamic power consumption
Up to 60MHz C28x™ core with optional control
With dedicated, high precision peripherals,
law accelerator. Up to 128KB Flash, high resolution
Piccolo microcontrollers are the ultimate
(150ps) PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
combination of performance, integration, size,
and low cost. Ideal for precision sensing and
control applications.
Up to 300MHz C28x™ core. Up to 512KB Flash, high
Delfino brings floating point and unparalleled
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN, QEP, performance to MCUs. Native floating point
external memory bus, DMA.
brings increased performance and quicker
development. Ideal for precision sensing and
control applications.
200MHz, dual MAC, very low standby power of
Supported by eXpressDSP™ and many other
0.12mW
software packages and tools
OMAP-L138
1.5pF cap, 1nA leakage
Low capacitance, small package
TPD2E001, TPD4E001
USB HS ESD with additional VBUS clamp
Replace one additional component for USB
charger application
TPD4S014
TMS320F283x Delfino,
TMS320F280x
TMS320F2802x/3x
Piccolo, TMS320F280x
TMS320VC5509A,
TMS320VC5502
Interface
TPD3E001
*Page 15
TPD4S012
*Page 15
3-Bit/Single-Channel
USB OTG ESD
4-Bit/Single-Channel
ESD with VBUS Clamp
additional product information see designated page number. To view more system block diagram compatible products, visit www.ti.com/medical
*For
Medical Applications Guide
20
New products are listed in bold red.
Texas Instruments 2010
Consumer Medical
➔ Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Interface (Continued)
TPD4E004
*Page 15
TPD4E002
*Page 15
TUSB3410
4-Bit/2-Channel
1.6pF cap, low DC breakdown voltage
Low capacitance, small package
4-Bit/2-Channel
USB FS
Very robust ESD (15kV contact)
USB 2.0 Full-Speed to
Enhanced Serial Port
Bridge
USB 2.0 Full-Speed Trans.
USB 2.0 compliance, enhanced UART port
TPD6E004
USB 2.0 compliance, level shifting, system-level ESD
Smaller package, no external ESD needed
Provides full safety for overvoltage, under
voltage, over current in discharge overvoltage
and short circuit in discharge conditions
Good for space-limited designs with need for
battery safety
The bq24040 comes with more safety features:
JEITA compliance, over-voltage protection, safety
timers, and ISET short protection.
Great for space-limited charger applications
USB Power Switch
Load Switch with
Controller Turn-On
Current Limited Load
Switch
USB Power Switch
Power Switch
LED Boost Converter
Integrated I2C communications interface allows the
bq77PL900 also to be as an analog front end (AFE) for
a host controller
Linear 1-cell Li-Ion charger with thermal regulation,
6.5V OVP, temp sense
30-V input rating and 6.6V overvoltage protection;
integrated 800mA FET and current sensor; USB and
JEITA compliant
One-cell Li-Ion charger with 1-A FET, timer enable and
temperature sensing
Li-Ion and Li-Pol battery gas gauge
Li-Ion battery gas gauge with Impedance Track™
fuel-gauge technology
USB compliant power source, short circuit protection
Low on resistance, controlled turn-on, ultra small
0.64mm2 package, quick output discharge
Configurable current limit, ultra-small package, 1µA
quiescent current at 1.8 V
USB compliant power source, short circuit protection
Adjustable current limit, 100mA to 1100mA
Input to output isolation
TPS61093
TPS61097-33
OLED Boost Converter
Boost Converter with
Bypass Switch
Wide VIN range, input-output disconnect
Highly efficient, operates down to 0.3V; bypass switch;
5nA shutdown current; SOT-23
TPS61160/61
*Page 17
Boost Converter
2.7V to 18V input voltage, up to 90% efficiency, built-in
soft start
TPS61200
TPS61220
*Page 16
TPS62230
TPS62300
TPS63030
Boost Converter
Boost Converter
TPS717xx
Low-Noise SingleChannel LDO
Dual-Channel LDO
LDO with DVS
High efficient, operates down to 0.3V
Low Input Voltage, 0.7V boost converter with 5.5μA
quiescent current
Up to 90dB PSRR, excellent AC and transient load regulation
500mA, 3MHz synchronous step-down converter
1-A switch, automatic transition between step down and
boost mode
High bandwidth, very high rejection of power-source
noise
Very high rejection of power-source noise
Dynamic voltage scaling (DVS) with low IQ 500nA
Single-Channel LDO
Dual-level, fixed output voltages, ultra-low IQ
CC1101
Sub-1GHz RF
Transceiver
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Wake-on-radio functionality; integrated packet
handling with 64B data FIFOs; high RF flexibility: FSK,
MSK, OOK, 1.2-500kbps; extremely fast PLL turn-on/
hop time
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended
temperature range; AES-128 security module
TUSB1106
TUSB1105, TUSB2551A
Power Management
bq77PL900
5-10 Series Li-ion
Battery Protection & AFE
bq2406x
Battery Charger
bq24040
*Page 17
USB-Compliant Li-Ion
Charger
bq24081
Battery Charger
bq27010
bq27541
*Page 18
TPS2041B
TPS22902
Battery Fuel Gauge
Battery Fuel Gauge
TPS22946
TPS2550
TPS2551
TPS61081
TPS718xx-yy
TPS780xx
TPS78001
*Page 16
Step-Down Converter
Step-Down Converter
Buck-Boost Converter
bq2410x
Reports accurate time-to-empty of battery
Reports accurate time-to-empty of battery
bq27200, bq27500
bq27510
USB switch with adjustable precision OC
Ultra-small, fully integrated solution
TPS2550
TPS22901, TPS22922,
TPS22924C, TPS22960
TPS22949, TPS22945
Ultra-small, low quiescent current current limited
switch
USB switch with adjustable precision OC
Allows designer to precisely set current limit
Protection from short between any pins and
between any pin to ground
Flexible, fail safe solution
Super efficient boost, works over entire battery
range, low quiescent current, integrate the bypass
switch, small package
The boost converter runs at 600kHz fixed switching
frequency to reduce output ripple, improve
conversion efficiency, and allows for the use of
small external components.
Super efficient boost, works over entire battery range
Can be switched off to minimize battery drain;
small package solution
Low noise regulation, 12mm2 solution size
Very small inductor and high efficiency
Extending application run time, small solution
Low-noise power rails for sensitive analog
components
Low-noise power rails for sensitive analog components
DVS voltage designed to operate with MSP430TM
to increase power savings
Adjustable VOUT for optimal performance, longer
battery life
TPS2551
TPS2051B, TPS2061
TPS61161
TPS61080
TPS61010
TPS62260
TPS62040
TPS61020
TPS799xx
TPS719xx-yy
TPS781xx
TPS717xx, TPS739xx
RF ICs
RF Transceivers
Ideal for low-power systems; any low-end
MCU can be used; backwards compatible with
existing systems; suitable for fast frequencyhopping systems
Reliable RF link with interference present; 400m
line-of-sight range with the development kit;
ideal for industrial applications; no external
processor needed for secure communication
CC2500
CC2530
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
21
Texas Instruments 2010
Consumer Medical
➔ Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
RF ICs (Continued)
RF Transceivers (Continued)
TMS37157
*Page 8
Passive Low
Frequency Interface
Device (PaLFI) With
EEPROM and 134.2
kHz Transponder
Interface
Ultra-low-power consumption, 2V to 3.6V supply
voltage, low frequency HDX interface
It is the ideal device for
any data logger, sensor or remote control
application enabling operation without
the need of a battery.
2.4GHz Bluetooth® 2.1
chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
MCU, USB 2.0, Flash and RAM in one package;
four flexible power modes for reduced power
consumption; includes CC1101 transceiver frequency
synthesizer; built-in AES-128 encryption coprocessor
Second Generation
System-on-Chip
Solution for 2.4GHz
IEEE 802.15.4/RF4CE/
ZigBee®
2.4 GHz Bluetooth®
low energy compliant
RF System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
Excellent RX sensitivity, low power, easy to use
development tools
Sophisticated low-power technology ideal for
battery operated solutions
Complete low-cost solution on single chip; ideal
for low-power battery-operated systems; robust
and secure link with good noise immunity;
no external processor needed for secure
communication; can connect directly to a PC
RF design System-on-Chip for quick time to
market. Provides a robust and complete ZigBee
USB dongle or firmware-upgradable network
node
2.4/5GHz 802.11a/b/g/n
and Bluetooth® 2.1
Chipset
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
RF Systems-on-Chip
CC2560
CC1110/1111
CC2530/31
CC2540
WL1271
WL1273
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity,
selectivity and blocking performance
Single-chip 802.11b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
CC2510, CC2511
CC2590/91,
CC2530ZNP
Fast-to-market Bluetooth® low energy compliant
solution
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
Sophisticated low-power technology ideal for
battery operated solutions; coexistence features
enable simultaneous WLAN and Bluetooth®
operations; supports ANT+ standard.
WL1273
WL1271
RF Network Processor
CC2530ZNP
Second Generation
Z-StackTM Network
Processor
ZigBee® stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings; excellent selectivity and blocking
performance
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Add CC2530ZNP and your system is ZigBee
enabled; ideal for battery operated systems;
excellent coexistence with Bluetooth® technology
and Wi-Fi.
22
New products are listed in bold red. Preview products are listed in bold blue.
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Overview
Trends in Medical Diagnostic, Patient
Monitoring and Therapy equipment
include portability, connectivity,
flexibility and system intelligence.
Medical equipment such as digital
stethoscopes, patient monitoring,
ECG, EEG, and pulse oximetry
have all become more portable
through improvements in battery and
battery management technologies,
and the proliferation of wireless
communications technologies like
Bluetooth® and ZigBee®. The addition
of features like touch screen control
and audio feedback have taken away
the complicated mix of knobs and dials
and replaced them with menu-driven
displays and user prompts. On top of
this the precision of the sensor signal
chain combined with the processing
power of today’s embedded
processors have paved the way for
these instruments to not only notice the
smallest perturbation from normality in
a signal, these devices can collect and
process trends against large databases
and even suggest a course of action.
These improvements in reliability,
battery storage capability and usability
have also taken the Automated
External Defibrillators (AEDs) from
equipment only found in medical
facilities and emergency vehicles
to tools deployed in many schools,
businesses and other public areas. Low power processing allows an AED
to sleep for long time periods, only
waking up to run diagnostics, and
then quickly get to full operation when
needed. Such as the intelligence to
guide the user safely through its use
and the ability to sense if the pads are
incorrectly placed on the patient have
truly helped drive the proliferation of
these devices.
By combining the advances in
monitoring capabilities with those seen
in motor control, power management,
and control systems, applications such
as ventilation/CPAP, dialysis, and
infusion pumps have been made
smaller, safer and less expensive. This trend has made it practical for
CPAP systems and Infusion pumps to
be placed in the home, and dialysis
therapy to move from a hospital-only
application to a doctor's office. Connectivity for portable medical applications has become critical as consumers and caregivers are requiring data
to move from medical devices to data
hubs such as computers and mobile
phones. TI is a promoting member
of the Continua Health Alliance and
now offers the first
Continua-certified
USB platform for
Agent Devices. See page 142 for
more information.
For more information on TI’s offering
for Diagnostic, Patient Monitoring
and Therapy, please visit www.ti.com/patientmonitoring
➔ Digital Stethoscopes
The main elements of a digital stethoscope (see page 24) are the sensor
unit that captures the heart and lung
sounds (also known as auscultations),
along with auscultation digitization and
digital processing for noise reduction,
filtering and amplification. Algorithms
for heart rate detection and heart
defect detection may also be included.
Power and battery management are
key in this ultra-portable diagnostic
tool. Design considerations include
ultra-low-power consumption and high
efficiency, both of which are driven
Medical Applications Guide
by the need for extended battery life. The design must also incorporate high
precision with a fast response time
to allow quick determination of the
patient’s health status. The need to record auscultations calls
for cabled or wireless interfaces that
transmit the auscultations. To enable
ease-of-use, features like touch-screen
control and display backlighting are
essential. Adding these features without significantly increasing power consumption is a huge challenge. 23
TI’s portfolio of processors, instrumentation and buffer amplifiers,
power and battery management,
audio codecs, and wired and wireless interface devices provides the ideal tool box for digital stethoscope applications.
The common core sub-systems of
a digital stethoscope are the analog front-end/sensor interface and
codec, low-power processor, and
data storage and transmission. Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Digital Stethoscopes
Analog Front-End/Sensor
Interface and Codec
Low-Power Processor
Memory
Power
FLASH/
EPROM
SDRAM
Processors that are able to execute the
digital stethoscope’s signal processing functions, such as noise reduction,
algorithms for heart rate detection and
heart defect detection, while maintaining a very low constant current draw
from the battery, are a good fit. Auscultation signal input is amplified
and digitized by the audio codec. Auscultations signals after being digitized are subjected to signal processing. They are then converted to analog
and sent to the stethoscope earpiece. The ability to control memory interfacing and peripheral devices is also helpful. Processors that manage the digital
display and keyed functions allow
auscultation waveforms to be displayed
and manipulated without additional
components.
Display
*Heart Rate Detection
*Heart Defects Detection
- Murmur
- Regurgitation
- Septal Defects
- Mitral Valve Prolapse
- Stenosis
Level Shift
Acoustic Amplifier
Tube
Keypad
MMC/
SD
Headphone
Amp
REF
Electret Condenser
Microphone
Logic
I2S
Control
2
Signals I C
Audio
Codec
Pre-Amp
Data
EMIF/I2C GPIO
LCD
Touch Screen
Control
Backlight
Processor
Clock
Common Interfaces
Bluetooth
Core
and I/O
Power
USB
USB
ESD
USB Port
LEGEND
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Lithium
Battery
Protection
Gas
Gauge
Battery
Charger
System
Power
Optional Battery Management
(Needed for Recharging)
AC/DC
Adapter
Battery
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Digital stethoscope
system
block
diagram.
Product Availability
and Design
Disclaimer
- The system block diagram depicted above and the devices recommended are
designed in this manner as a reference. Please contact your local TI sales office or distributor for system design specifics
and product availability.
Medical Applications Guide
24
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Digital Stethoscopes
Power-Efficient Fixed-Point DSP
TMS320C5515
Get samples, datasheets, tools and application reports at: www.ti.com/sc/device/TMS320C5515
Key Features
• High-performance/low-power,
C55x™ fixed-point DSP
• 16.67/13.33/10/8.33ns instruction
cycle time
• 60, 75, 100, 120MHz clock rate
• 320K bytes on-chip RAM
• 16-/8-bit external memory interface
(EMIF)
• Two multi-media card/secure digital I/Fs
• Serial-port I/F (SPI) with four
chip-selects
• Four inter-IC sound (I2S bus™)
• USB 2.0 full- and high-speed device
• LCD bridge with asynchronous
interface
• Tightly-coupled FFT hardware
accelerator
• 10-bit 4-input SAR ADC
The TMS320C5515 is a member of TI’s TMS320C5000™ fixed-point digital signal
processor (DSP) product family and is designed for low-power applications.
The TMS320C5515 fixed-point DSP is based on the TMS320C55x™ DSP generation CPU processor core. The C55x™ DSP architecture achieves high performance
and low power through increased parallelism and total focus on power savings. The CPU supports an internal bus structure that is composed of one program bus,
one 32-bit data read bus and two 16-bit data read buses, two 16-bit data write
buses, and additional buses dedicated to peripheral and DMA activity.
These buses provide the ability to perform up to four 16-bit data reads and two
16-bit data writes in a single cycle.
DSP System
Input
Clock(s)
JTAG Interface
C55x™ DSP CPU
PLL/Clock
Generator
FFT Hardware
Accelerator
Power
Management
64 KB DARAM
Pin
Multiplexing
256 KB SARAM
128 KB ROM
Switched Central Resource (SCR)
Applications
• Portable ultrasound
• Automatic external defibrillator (AED)
• Electrocardiogram (ECG)
• Digital stethoscopes
• Cochlear implants
Peripherals
Interconnect
DMA
(x4)
Program/Data Storage
Serial Interfaces
I2 S
(x4)
I2 C
SPI
App-Spec
Display
Connectivity
10-Bit
SAR
ADC
LCD
Bridge
USB 2.0
PHY (HS)
[DEVICE]
NAND, NOR,
SRAM, mSDRAM
UART
MMC/SD
(x2)
System
RTC
GP Timer
(x2)
GP Timer
or WD
LDOs
TMS320C5515 DSP block diagram.
Medical Applications Guide
25
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Digital Stethoscopes
Digital Stethoscope (DS) Analog Front End Module for the C5515 DS Medical Development Kit
TMDXMDKDS3254
Get samples, datasheets and evaluation modules at: www.ti.com/tmdxmdkds3254
Key Features
• DS AFE module key components
• TLV320AIC3254: flexible, lowpower, low-voltage stereo audio
codec with programmable inputs
and outputs
• OPA335: 0.5µV/°C, CMOS
zero-drift operational amplifier
• DS MDK system features
•Based on industry’s lowest power
DSP processor – TMS320C5515
•Audio output in three selectable
modes:
- Bell mode (20Hz to 220Hz)
- Diaphragm mode (50Hz to 600Hz)
- Extended Range (20Hz to 2000Hz)
•Three channel input options, two
condensor and one contact
microphone
•Volume control and mute
•Real time display of heart signal on
onboard LCD and PC
•Store and playback option on PC
side
To reduce the time to market for medical device companies, TI has launched a set of medical application development tools with complete signal chain designs
and software for electrocardiograms, digital stethoscopes, and pulse oximeter
products. Each of the three medical development kits (MDKs) is comprised by purchasing an analog front-end (AFE) module with specific circuitry design optimized for each end product plus a TMS320C5515 DSP evaluation module (EVM)
based on the industry’s lowest power DSP—TMS320C5515. MDKs provide a great evaluation platform to help medical device manufacturers focus on product
differentiation, like algorithm development and feature enhancement. The TMDXMDKDS3254 Digital Stethoscope (DS) Analog Front End (AFE) module
consists of the DS AFE module, a processor board (C5515 DSP evaluation module),
a set of collateral and C5515-based application sample code to implement the
DS application. The DS MDK delivers a complete signal chain solution to enable
developers to build an entire DS system quickly for evaluation and get to production faster. Applications
• Digital stethoscope devices
• Patient monitoring
Medical Applications Guide
TMDXMDKDS3254 EVM.
26
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Digital Stethoscopes
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
Laptop-like performance at handheld power levels
OMAP-L137
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
TMS320C5505
Low-Power DSP
TMS320C5515
*Page 25
TMS320VC5503
Power-Efficient
DSP
Low-Power DSP
16-/8-bit EMIF, 320K bytes on-chip RAM, USB 2.0
full- and high-speed device
16-/8-bit external memory interface, 320K bytes on-chip
RAM, USB 2.0 full- and high-speed device
Up to 200MHz, dual MAC, 16-bit HPI, 3 McBSP
Highly integrated, dual-core solution drives low system
cost and maximum flexibility for connectivity, GUI and
high-level OS options. Extends product battery life
by providing greater than 60% power reduction over
existing solutions in the market.
High-performance, low-power
TMS320VC5507
Low-Power DSP
TMS320VC5509A
Low-Power DSP
Up to 200MHz, dual MAC, 128KB RAM/64KB ROM,
USB 2.0 full speed, 10-bit ADC
Up to 200MHz, dual MAC, 256KB RAM/64KB ROM,
USB 2.0 full speed, MMC/SD, 10-bit ADC
Designed for low-power applications; low-power,
high-performance
Power efficient, low-cost DSP, C55x™ code
compatibility
Power efficient, C55x code compatibility
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L138
C550x DSP
C550x DSP
Power efficient, large on-chip memory, rich
peripheral set allows for various portable
connectivity; C55x code compatibility
C550x DSP
Longer battery life, better audio quality, lower
system cost
TLV320AIC3204 (pin to
pin without miniDSP)
Data Converters
TLV320DAC32
Low-Power
Audio DAC
Low-Power
Audio Codec
Low-Power
Audio Codec
Low-Power
Audio Codec
Low-power stereo DAC, 4 outputs, HP/speaker amplifier,
3D effects
Low-power stereo codec, 6 inputs, 6 outputs, headphone
amp, enhanced digital effects
Low-power stereo codec, 6 inputs, 6 outputs, headphone
amp, enhanced digital effects
Very-low power, single supply, miniDSP for audio
processing
DRV134/5
Line Driver/
Receiver
0.0005% at f = 1kHz distortion, 17Vrms into 600Ω output
swing, ±5.2mA IQ, ±4.5V to ±18V supply
Balanced output pair, low distortion
INA134, INA137
INA134/2134
Line Driver/
Receiver
0.0005% at f = 1kHz distortion, 90dB CMRR, 0dB (1V/V)
fixed gain, ±2.9mA IQ, ±4V to ±18V supply
Excellent AC specifications, low distortion
INA137, OPA1632
INA137/2137
Line Driver/
Receiver
Differential line receiver, low distortion
INA134, DRV134
OPA134/2134
Audio Amp
0.0005% at f = 1kHz distortion, 90dB CMRR, 6dB fixed
gain, ±2.9mA IQ, ±4V to ±18V supply
—
0.00008% ultra-low distortion, 8nV/√Hz noise, 8MHz BW,
120dB open-loop gain, ±2.5V to ±18V supply
True FET-input stage, low distortion, low noise
OPA211, OPA604
OPA141
Precision Op Amp
Common mode voltage range includes GND
OPA827, OPA132
OPA209
Precision Op Amp
Unity gain stable, RRO, wide supply range, low
power
OPA211
Precision Op Amp
10MHz, 6.5nV/√Hz, ±4.5V to ±18V, 1.8mA typical, FET
input: IB = 20pA max
—
2.2nV/√Hz at 1kHz, ±4.5V to 18V supply, 18MHz, 2.5mA
quiescent current (typ)
—
1.1nV/√Hz noise at 1kHz, ±2.25V to ±18V supply, 80MHz
BW
Unity gain stable, RRO, wide supply range
OPA227
OPA378
Low Noise
Precision Op Amp
0.1µV/°C Vos drift, 125µA, 900kHz, 0.4μVPP (0.1Hz to
10Hz) 0.4µ Vpp (0.1Hz to 10Hz), 0.9MHz
Lowest noise, power, price, precision zero-drift
option
OPA330, OPA333
OPA827
Precision JFET Op
Amp
4nV/√Hz noise at 1kHz, ±4V to ±18V supply, 15pA (typ)
input bias current, 22MHz BW
High precision, low noise, low input bias, wide
supply range
OPA177, OPA627,
THS4521
Low Power FDA
1.14mA quiescent current (typ), 4.6nV/√Hz voltage noise
Very low power, low noise enables high accuracy
ESD Solution
Low capacitance, 2 channels, ±15kV ESD-protection
array for high-speed data interfaces
IEC 61000-4-2 system level (level 4) ESD protection;
low input capacitance in space-saving packages
TLV320AIC3104
TLV320AIC3106
TLV320AIC3254
Amplifiers
Interface
TPD2E001
New products are listed in bold red. Preview products are listed in bold blue.
view more system block diagram compatible products, visit www.ti.com/medical
To
Medical Applications Guide
SN65220
27
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Digital Stethoscopes
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management
bq29312A
Li-Ion Battery
Protection IC
Provides under- and overvoltage, overcurrent, shortcircuit and overtemperature protection
Provides primary safety protection for cells
bq29330
Battery Safety
Battery pack full-protection analog front end
Provides individual cell voltages and battery
voltage to battery-management host
bq29410/1/2
Li-Ion Battery
Protection IC
Provides overvoltage protection for Li-Ion and poly cells
Prevents false triggers during dynamic operating
conditions
bq2000
Battery
Management
Multi-chemistry charger
One charge for both Li-Ion and NiCad/NiMH cells
bq24100
Battery Charge
Management
Switch mode, 1100kHz switching frequency, >2A charge
current
d/dt, min current primary charge termination
method
TPS5130
DC/DC Converters
Triple synchronous buck controller with LDO
Provides 4 output voltages in 1 package
TPS61070
DC/DC Converters
600mA switch low voltage in boost
Can generate 5V rail from 1-, 2- or 3-cell alkaline
or 1-cell Li-Ion
TPS61097-33
Boost Converter
with Bypass Switch
Highly efficient, operates down to 0.3V; bypass switch; 5nA
shutdown current; SOT-23
Super efficient boost, works over entire battery range,
low quiescent current, integrate the bypass switch,
small package
TPS61120
DC/DC Converters
Dual switcher boost and LDO
Compact 2-voltage solution
TPS62202
DC/DC Converters
300mA synchronous
Ultra-small battery-powered solutions
TPS22902
Load Switch with
Controller Turn-On
Low on resistance, controlled turn-on, ultra small 0.64mm2
package, quick output discharge
Ultra-small, fully integrated solution
TPS65020
Linear Charge
Management
6-channel power management IC with 3 DC/DCs, 3 LDOs,
I2C interface and dynamic voltage scaling
Provides complete solution in one package
TPS65023
Linear Charge
Management
6-channel power management IC with 3 DC/DCs, 3 LDOs,
I2C interface and DVS, optimized for DaVinci™ DSPs
Provides complete DaVinci solution in one package
TPS65800
Linear Charge
Management
6-channel power management IC with 2 DC/DCs, 7 LDOs,
I2C interface and dynamic voltage scaling
Complete power management solution in one
package
TPS74401
LDO
Single-output LDO, 3.0A, adjustable (0.8V to 3.3V), fast
transient response, programmable soft start
Adjust the voltage ramp rate for your processor
requirements
TPS79601
LDO
1A low-dropout regulator with high PSRR
Low-noise LDO stable with 1µF ceramic capacitor
TPS796xx
TPS79630
LDO
1A low-dropout regulator with high PSRR
Low-noise LDO stable with 1µF ceramic capacitor
TPS796xx
Digital
Stethoscope (DS)
Analog Front End
Module for the
C5515 DS Medical
Development Kit
Audio output in three selectable modes; 3 channel input
options; volume control and mute; real time display of
heart signal on onboard LCD and PC; store and playback
option on PC side
Based on industry’s lowest power DSP processor –
TMS320C5515
TPS22901, TPS22922,
TPS22924C, TPS22960
Toolkits
TMDXMDKDS3254
*Page 26
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
28
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Patient Monitoring
A variety of portable, single and multipleparameter monitors have emerged
over the last few years that measure
blood pressure, glucose levels, pulse,
tidal carbon dioxide and other biometric values. Patient monitors are
portable, flexible devices that can be
adapted to a wide range of clinical
applications and support various wired
and wireless interfaces. Key Features
The most important features of today’s
patient monitors are mobility, ease-ofuse and effortless patient data transfer. Mobility includes portability as well
as the ability to interface with other
medical devices such as anesthesia
machines and defibrillators. Ease-ofuse can be achieved with touch-screen
displays and multi-level, menu-driven
profiles that can be configured for the
environment and the patient’s vital
statistics. Data transfer across everything from
wireless to RS-232 must be possible. While hospitals may support a
specific infrastructure throughout all
areas, ambulance, home and other
An ongoing need to minimize healthcare costs is creating a move toward
patient treatment and monitoring
outside of the hospital. This shift is
placing an emphasis on remote patient
monitoring and telemedicine solutions
that enable providers to treat patients
in highly populated, rural and remote
areas in emerging economies. Backlight
Patient Monitoring
and Data Upload
Touch
Screen
Control
Display
Connectivity
LVDS
SerDes
WiFi/Zigbee
PC, Monitor & Keyboard
environments often require support for
different protocols. Bluetooth
S-Video
TV
Clock
Low Power Wireless
Ethernet
Audio/Video
Codec
Analog Front End
HS USB
Transceiver
(ECG, Pulse Oximetry,
Blood Pressure, Other)
Processor
Integrated ECG
Front End
Keypad
Control
Audio
Feedback
USB
Protection
Keypad
Power
Manager
USB Port
LED
Drivers
Inst AMP
Battery
Charger
Power Source
Buffer AMP
ADC
Human Body
On/Off
Level
Shifter
Isolation
MS/MMC/
SD/SDIO
Card
Core and I/O
Supply
Gas
Gauge
System
Power
AC/DC
Supply
Battery
LEGEND
Plug
Main Power Supply
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Multi-parameter patient monitor system block diagram.
Medical Applications Guide
29
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Patient Monitoring
TI’s OMAP™/Davinci™
Technology Solution
The challenges involved in implementing patient treatment and monitoring
equipment are similar to systems
implementation challenges faced by
the cellular phone industry. TI’s
OMAP™ technology, with embedded
ARM® and DSP processor cores,
directly addresses these challenges. TI has an extensive portfolio of analog
front-end solutions for essential signal
conditioning. The OMAP 3 processor enables digital signal processing,
measurements and analytics needed to
monitor patient condition. TI’s powerful
ARM processor runs a high-level OS
(HLOS) that makes adding multi-modal
monitoring easy and provides extensive user interface and system control. Detecting abnormal conditions and
communicating to a central server are
essential to providing timely and on-demand healthcare. OMAP 3 has
an innovative peripheral set that supports connectivity options such as
Bluetooth® technology, WiFi®, ZigBee®
and other emerging standards.
Applications Processor
OMAP35x
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/omap35x
Key Features
• ARM® Cortex-A8 core
• TI’s DaVinci™ C64x+™ DSP core
• 2D/3D graphics accelerator
• OpenGL® ES 2.0 compatible
graphics engine
• Neon™ coprocessor
• Scalable platform:
• OMAP3503 (ARM-only version)
• OMAP3515 (ARM and 2D/3D
graphics accelerator)
• OMAP3525 (ARM and DSP)
• OMAP3530 (ARM, DSP and 2D/3D
graphics accelerator)
• Optimized laptop-like performance
at handheld power levels in a single
chip
• TI’s SmartReflex™ power and
perform­ance management
• 65nm CMOS
The OMAP35x generation of processors includes four distinct single-chip
­processors with a variety of combinations of the ARM® Cortex-A8 core, multimedia-rich peripherals, OpenGL® ES 2.0 compatible graphics engine, video
accelerators and the high-performing TMS320C64x+™ DSP core. Offering laptoplike perform­ance at handheld power levels, the OMAP35x provides users with a
highly flexible platform capable of creating a powerful user interface experience,
with additional signal processing for application implementation. In addition, TI’s
SmartReflex™ power and performance management technologies reduce overall
power consump­tion and optimize performance, allowing users to develop innovative, low-power applications. The processor provides a range of interfaces for analog front ends, power and battery monitoring, displays, keypads and touch-screen
solutions. Also, support for various connectivity options such as USB, Wi-Fi®,
ZigBee®, Ethernet and other emerging standards is integrated into the processor. ®
ARM
®
CORTEX -A8
CPU
Applications
• Multiparameter patient monitors
• Portable ultrasound
• Automatic external defibrillator (AED)
• Electrocardiogram (ECG)
Display Subsystem
C64x+™ DSP and
Video Accelerators
(3525/3530 only)
LCD
10-Bit DAC
Con- Video
troller Enc 10-Bit DAC
2D/3D
Graphics
(3515/3530 only)
Camera I/F
Image
Pipe
Parallel I/F
L3/L4 Interconnect
Peripherals
Connectivity
System
USB 2.0 HS
USB
OTG
Host
Controller Controller ×2
Timers
GP ×12
WDT ×2
Serial Interfaces
McBSP
×5
2
IC
×3
UART
×2
UART
w/IrDA
McSPI
×4
Program/Data Storage
HDQ/1-Wire
SDRC
GPMC
MMC/
SD/
SDIO
×3
OMAP35x processor.
Medical Applications Guide
30
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Patient Monitoring
Stellaris®
LM3S3xxx
Get samples, datasheets, evaluation modules at: www.ti.com/stellaris
Key Features
• Up to 256kB integrated flash and
96kB SRAM
• Integrated ethernet MAC+PHY
• USB host/device/on-the-go
• Free license for complete and rich
software libraries (StellarisWare®)
Applications
• Patient monitoring
• Home health hubs
Designed for high-end microcontroller applications, the Stellaris family provides the
entry into the industry’s strongest ecosystem, with code compatibility ranging from $1
to 1GHz. • Superior integration saves up to $3.28 in system cost
• Over 160 Stellaris family members to choose from
• Real MCU GPIOs—all can generate interrupts, are 5V-tolerant, and have programmable drive strength and slew rate control
• Advanced communication capabilities, including 10/100 Ethernet MAC/PHY, USB and USB OTG, CAN controllers, and extended peripheral interfaces
• Sophisticated motion control support in hardware and software
• Both analog comparators and ADC functionality provide on-chip system options to balance hardware and software performance
• Development is easy with the royalty-free StellarisWare software
32
JTAG
256 KB Flash
NVIC
ARM
Cortex™-M3
SWD
100 MHz
32
96 KB SRAM
32
ROM
Clocks, Reset
System Contol
3 UARTs
Systick Timer
10/100 Ethernet
MAC + PHY
IEEE 1538
2 Watchdog Timers
USB Full Speed
GPIOs
Host / Device / OTG
3 CAN
32ch DMA
2 I2C
EPI
I2S
Precision
Oscillator
2 Quadrature
Encoder Inputs
8 PWM Outputs
Timer
Comparators
R
Y
C
32
Battery-Backed
Hibernate
LDO Voltage
Regulator
3 Analog
Comparators
PWM
PWM
Generator Interrupt
2x 10-bit ADC
Each 8 channel
1 Msps
Dead-Band
Generator
Temp Sensor
ANALOG
MOTION CONTROL
4 Timer/PWM/CCP
Each 32-bit or 2x16-bit
SYSTEM
SERIAL INTERFACES
2 SSI/SPI
Stellaris family block diagram.
Medical Applications Guide
31
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Patient Monitoring
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
AM3517
OMAP3530
*Page 30
OMAP-L137
Applications
Processor
Applications
Processor
Low-Power
Applications
Processor
Stellaris®
LM3S3xxx *Page 31
Microcontroller
ARM® Cortex-A8, graphics acelerators, Ethernet, CAN
High performance at handheld power levels
AM3505
ARM Cortex-A8, C64x+™, graphics accelerator,
video accelerators
300MHz ARM9™ w/MMU + 300MHz C674x™
floating-point DSP core, rich peripheral set including
10/100 Ethernet MAC, LCD controller, USB 2.0 HS
OTG, USB 1.1 full speed, SPI and MMC/SD
ARM® Cortex-M3, up to 256KB flash, up to 64kB
RAM, USB host/device
Laptop-like performance at handheld power levels
OMAP3503, OMAP3515,
OMAP3525
OMAP-L138
16-bit, 860SPS, 4 SE, 2 diff input, PGA, MUX,
comparator, VREF
24-bit, 8 PGA, 8 ADC, plus RLD and RESP
Smallest 16-bit ADC, 2.0 x 1.5 x .04 mm leadless WFN
pkg; reduces system size and componenent count
Complete front end, reduction in power and size,
increase reliability
Small size, low power, serial interface
ADS1113/4,
ADS1013/14/15
ADS1294, ADS1296,
ADS1198, ADS1258
ADS7886
Intelleigent system power management and self
monitoring
Low power, small package, and excellent
performance
Full on-chip data acquisition system
ADS7828, ADS7823
Low power, small package, and wide supply range
ADS8317
Longer battery life, better audio quality, lower cost
TLV320DAC3101
Longer battery life, better audio quality, lower
system cost
TLV320AIC3204 (pin2pin
without miniDSP)
±250μV (max) input offset, 83dB CMRR, 0.175mA
(typ) IQ
—
60µV offset, 0.7 µV/°C drift, 8nV/√(Hz) noise
Precision low power, ±1.35V to ±8V supply
INA2126, INA122
Low noise, low drift, wide supply, wide BW
INA118, INA129
25μV (max) offset, 50nV/°C drift, 50μA (typ) Iq
Best offset/noise combination, supply down to 1.8V,
low power
High speed, wide input and output voltage swing,
excellent DC accuracy
Zero drift, high precision, low power, EMI input
INA321, INA326
®
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
USB, 10-bit ADC, temperature sensor
Data Converters
ADS1115
Delta-Sigma ADC
ADS1298
ECG/EEG AFE
ADS7866
SAR ADC
ADS7924
Low-Power SAR
ADC
SAR ADC
ADS7953
ADS8201
ADS8326
Micropower SAR
ADC
SAR ADC
TLV320AIC3104
Audio Codec
TLV320DAC3120
Low-Power Audio
DAC
Low-Power Audio
Codec
Audio DAC
TLV320AIC3254
TLV320DAC32
12-bit, 200kSPS, 71dB SNR, ±1.5 LSB (max) INL,
1.6V to 3.6V supply
12-bit, 100kSPS, 4 channel, ≤1µA power down
current, I2C interface, QFN package
12-bit, 16-channel, 1MSPS, SPI interface with
threshold alarms, QFN package
8 channel, 12-bit, 100kSPS, 1.32mW power
consumption at 100kSPS
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max)
INL, SE input
Low-power stereo codec, 6 inputs, 6 outputs,
headphone amp, enhanced digital effects
Mono DAC with 2.5W mono Class-D speaker
amplifier; miniDSP for audio processing
Very-low power, single supply, miniDSP for audio
processing
Low-power stereo DAC, 4 outputs, HP/speaker
amplifier, 3D effects
ADS7952, ADS7956,
ADS7957/60/61
ADS7870
Amplifiers
INA126
OPA2822
Instrumentation
Amp
Instrumentation
Amp
Instrumentation
Amp
High-Speed Amp
OPA333
Precision Op Amp
OPA376
Precision Op Amp
OPA378
Low Noise
Precision Op Amp
High-Speed Amp
INA128
INA333
OPA695
TPA2006D1
TPA2010D1
TPA2013D1
TPA3007D1
TPA6205A1
TPA6211A1
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Class-AB Audio Amp
Class-AB Audio Amp
—
Dual, 2nV/√Hz noise, 240MHz GBWP, 90mA output,
4.8mA/ch IQ, +5V to +12V supply
1.8V min supply, 0.017mA/ch (max), 10μV offset
(max), 0.05 μV/°C drift (max)
7.5nV/√Hz noise, 760μA(typ)/ch Iq, 5μV (typ) offset,
input EMI filter, RRO
0.1µV/°C Vos drift, 125µA, 900kHz, 0.4μVPP (0.1Hz to
10Hz) 0.4µ Vpp (0.1Hz to 10Hz), 0.9MHz
1.4GHz BW (G = +2), 4300V/µs slew rate, 129mW
power, ±4.2V output voltage swing
1.45W mono, filter-free Class D, 1.8V shutdown
OPA2690, OPA842
OPA335, OPA378,
OPA330
OPA340, OPA337,
OPA364
OPA330, OPA333
Low noise, low power, low input bias
Lowest noise, power, price, precision zero-drift
option
Wide bandwidth, current feedback, low power, fast
signal conditioning
OPA847, OPA691
2.5W mono, fully differential, filter-free Class D, in
WCSP
2.7W constant output power, mono, Class D,
integrated boost converter
Mono, medium power, filter-free Class D
Loud audio, long battery life, small package size
TPA2031D1
Louder audio at low battery levels
TPA2014D1
1.25W mono, fully differential, Class AB, 1.8V shutdown
3.1W mono, fully differential, Class AB
Loud audio, low cost
Loud audio
TPA6204A1
Wake-on-radio functionality; integrated packet handling
with 64B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2 to 500kbps; extremely fast PLL turn-on/hop time
Programmable data rate from 1.2 to 500 kBaud, fast
startup time (0.3µs), low current consumption
Ideal for low-power systems; any low-end MCU can
be used; backwards compatible with existing systems;
suitable for fast frequency hopping systems
Fast development time and low system cost, flexible
optimization of range vs. power, small solution size
CC2500
RF ICs
RF Transceivers
CC1101
Sub-1GHz RF
Transceiver
CC1150
Sub-1GHz
Transmitter
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
New products are listed in bold red. Preview products are listed in bold blue.
32
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Patient Monitoring
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
RF ICs (Continued)
RF Transceivers (Continued)
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended
temperature range; AES-128 security module
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal
for industrial applications; no external processor
needed for secure communication
CC2530
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital
radio processor technology.
MCU, USB 2.0, Flash and RAM in one package;
four flexible power modes for reduced power
consumption; includes CC1101 transceiver frequency
synthesizer; built-in AES-128 encryption coprocessor
Second Gen.
System-on-Chip
Solution for 2.4GHz
IEEE 802.15.4/
RF4CE/ZigBee®
2.4 GHz Bluetooth®
Low Energy
compliant RF
System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
Excellent RX sensitivity, low power, easy to use
development tools
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
RF design System-on-Chip for quick time to
market. Provides a robust and complete ZigBee
USB dongle or firmware-upgradable network node
RF Systems-on-Chip
CC2560
CC1110/11
CC2530/31
CC2540
WL1271
WL1273
Excellent link budget enabling long range
applications without external frontend, receiver
sensitivity, selectivity and blocking performance
RF design System-on-Chip for quick time to
market. Provides a robust and complete ZigBee
USB dongle or firmware-upgradable network node
Single-chip 802.11b/g/n WLAN and Bluetooth®
solution using TI’s digital radio processor technology
using a single antenna.
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
Fast-to-market Bluetooth® low energy compliant solution
CC2510, CC2511
CC2590/91, CC2530ZNP
CC2590/91, CC2530ZNP
Sophisticated low-power technology ideal for
battery operated solutions; coexistence features
enable simultaneous WLAN and Bluetooth®
operations; supports ANT+ standard.
WL1271
RF Network Processor
ZigBee® stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings; excellent selectivity and blocking
performance
Add CC2530ZNP and your system is ZigBee
enabled; ideal for battery operated systems;
excellent coexistence with Bluetooth® technology
and Wi-Fi.
Multi-chemistry charger
One charge for both Li-Ion and NiCad/NiMH cells
TPS43000
TPS5130
Battery
Management
Battery Charge
Management
DC/DC Controller
DC/DC Controller
Switch mode, 1100kHz switching frequency, >2A
charge current
2MHz operation
Triple synchronous buck controller and LDO
TPS61070
DC/DC Converter
Input voltage range of 0.9V to 5.5V
TPS61097-33
Boost Converter
with Bypass
Switch
DC/DC Converter
Highly efficient, operates down to 0.3 V; bypass switch;
5nA shutdown current; SOT-23
d/dt, min current primary charge termination
method
Allows smaller-value inductor and input cap
Four outputs in one package allows smaller power
solution
Allows 1-, 2- or 3-cell alkaline or 1-cell Li-lon
operation
Super efficient boost, works over entire battery range,
low quiescent current, integrates the bypass switch,
small package
Highly efficient dual-output operation for 1-cell
Li-Ion operation
Ultra-small, fully integrated solution
CC2530ZNP
Second
Generation
Z-StackTM
Network Processor
Power Management
bq2000/T
bq24100
TPS61120
TPS22902
TPS22946
TPS62420
TPS62202
TPS65020
TPS65023
TPS65800
Load Switch with
Controller Turn-On
Current Limited
Load Switch
DC/DC Converter
DC/DC Converter
Linear Charge
Management
Linear Charge
Management
TPS74401
Linear Charge
Management
LDO
TPS79601
TPS79630
LDO
LDO
Dual switch boost and 200mA LDO outputs
Low on resistance, controlled turn-on, ultra small
0.64mm2 package, quick output discharge
Configurable current limit, ultra-small package, 1µA
quiescent current at 1.8 V
Dual step-down buck converter with 1-pin easy scale
300mA synchronous buck in a SOT-23 package
6-channel power management IC with 3 DC/DCs,
3 LDOs, I2C interface and dynamic voltage scaling
6-channel power management IC with 3 DC/DCs,
3 LDOs, I2C interface and DVS, optimized for
DaVinci™ DSPs
6-channel power management IC with 2 DC/DCs,
7 LDOs, I2C interface and dynamic voltage scaling
Single-output LDO, 3.0A, adjustable (0.8V to 3.3V),
fast transient response, programmable soft start
1A low-dropout regulator with high PSRR
1A low-dropout regulator with high PSRR
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Ultra-small, low quiescent current current limited
switch
Offers dynamic voltage scaling for power savings
Ultra-small implementation
Provides complete solution in one package
TPS65xxx
TPS22901, TPS22922,
TPS22924C, TPS22960
TPS22949, TPS22945
Provides complete DaVinci solution in one package
Complete power management solution in one
package
Adjust the voltage ramp rate for your processor
requirements
Low-noise LDO stable with 1µF ceramic capacitor
Low-noise LDO stable with 1µF ceramic capacitor
TPS796xx
TPS796xx
New products are listed in bold red. Preview products are listed in bold blue.
33
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Biophysical Monitoring Overview
wall contraction spreads electrical cur­
rents from the heart throughout the body. The spreading electrical currents create
different potentials at different points
on the body, which can be sensed by
electrodes on the skin surface using
biological transducers made of metals
and salts. This electrical potential is an
AC signal with bandwidth of 0.05Hz to
100Hz, sometimes up to 1kHz. It is
generally around 1mV peak-to-peak in
the presence of much larger external
high frequency noise plus 50/60Hz
interference normal-mode (mixed with the electrode signal) and common-mode voltages (common to all
electrode signals).
The human medical data acquisition
system, in particular the patient monitoring system, presents the challenge
to designers of measuring very small
electrical signals in the presence of
much larger common-mode voltages
and noise. Front-end amplifiers perform
the essential conditioning that complements downstream digital processing,
which in turn refines the measurement
and communicates with other systems. Biophysical measurements include
electrical and mechanical signals for
general monitoring, diagnostic and
scientific purposes both in clinic and
non-clinic environments. Successfully
meeting the signal acquisition challenge requires system designers to
have knowledge of the signal source,
good design practice and ICs with
appropriate characteristics, features
and performance.
The common-mode is comprised of
two parts: 50Hz or 60Hz inter­ference
and DC electrode offset potential. Other noise or higher frequencies
within the biophysical bandwidth come
from movement artifacts that change
the skin-electrode interface, muscle
contraction or electromyographic
Signal Acquisition Challenges
The action potential created by heart
spikes, respiration (which may be
rhythmic or sporadic), electro­magnetic
interference (EMI), and noise from other
electronic components that couple into
the input. Some of the noise can be
cancelled with a high-input-impedance
instrumentation amplifier (INA), like the
INA333 or INA118, which removes the
AC line noise common to both inputs
and amplifies the remaining unequal
signals present on the inputs; higher
INA common-mode rejection (CMR)
will result in greater rejection. Because
they originate at different points on the
body, the left-arm and right-arm ECG
signals are at different voltage levels
and are amplified by the INA. To further
reject 50 and 60Hz noise, an operational amplifier deriving common-mode
voltage is used to invert the commonmode signal and drive it back into
the patient through the right leg using
amplifier A2. Only a few microamps or
less are required to achieve significant
CMR improvement and stay within the
UL544 limit.
Backlight
LCD
Integrated Analog Front End
Input
Buffer
Touch Screen Control
Low Pass
(DC)
Filter
ADC
Mux
Wireless:
Zigbee
Bluetooth
Display
Driver
High
Pass
Filter
ADC
Summer
(resistive)
RLD
Temp Sense
Clock
Core
and I/O
Power
Low Noise Power
AC Line
Wired:
USB
RS232
Logic
Battery
Management
DDR
Power
FLASH/
EEPROM
Green
Mode
Control
DSP/OMAP
SDRAM
AC/DC
Supply
Signal
Processor
Level Shift
Human Body
Plug
Isolation
DS Converter
Ref
Memory
Power Management
P
M
t
LEGEND
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Three ECG electrodes connected to patient using CMOS components with 5V single supply. This circuit will
operate on a 3.3V supply.
Medical Applications Guide
34
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Supply Voltage
Frequency Response
As in most other applications, the system supply voltage in biophysical
monitoring continues the trend toward
low, single-supply levels. While bipolar
supplies are still used, 5V systems are
now common and trending to single
3.3V supplies. This trend presents a
significant challenge for the designer
faced with at least a 300mV DC electrode potential and emphasizes the
need for a precision signal-conditioning
solution. Standard –3dB frequency bandwidth
for patient monitoring is 0.05Hz to 30Hz,
while diagnostic grade monitoring
requires 0.05Hz to 100Hz or more. The
analog front end must be AC coupled
to remove artifacts from the electrode
offset potential. Operational Amplifier
Requirements
• Low noise in high gain (Gain = 10 to 1000)
• Rail-to-rail output
• Very low offset and drift
Connectivity for ECG/EEG equipment
has become of interest as caregivers
require data to move from medical end
equipment to data hubs such as the
hospital/clinic IT infrastructure, computers or even mobile phones.
Instrumentation Amplifier
Requirements
• Stability in low gain (Gain = 1 to 10)
• High common-mode rejection
• Low input bias current (IB)
• Good swing to the output rail
• Very low offset and drift
Low-Power Applications Processor
OMAP-L137
Get datasheets, samples and technical documents at: www.ti.com/sc/device/omap-l137
The OMAP-L137 is a low-power applications processor based on an ARM926EJ-S™
and a C674x DSP core. It consumes significantly lower power than other members
of the TMS320C6000™ platform of DSPs. The OMAP-L137 enables OEMs and
ODMs to quickly bring to market devices featuring robust operating systems support, rich user interfaces, and high processing performance life through the maximum flexibility of a fully integrated mixed processor solution. The dual-core architecture of the OMAP-L137 provides benefits of both DSP and Reduced Instruction
Set Computer (RISC) technologies, incorporating a high-performance TMS320C674x
DSP core and an ARM926EJ-S core. The ARM926EJ-S is a 32-bit RISC processor core
that performs 32-bit or 16-bit instructions and processes 32-bit, 16-bit, or 8-bit data.
PRU Subsystem
DSP
Subsystem
ARM9
Subsystem
ARM
926EJ-S
CPU
2x PRU
4K+4K Prog
512+512 Data
C674x
DSP
Core
L1P 32K
L1D 32K
L2 256K
L1P 18K
L1D 18K
GPIOs
Key Features
• Dual core SoC
• 300MHz ARM926EJ-S™
RISC MPU
• 300MHz C674x VLIW DSP
• TMS320C674x fixed/floating-point
VLIW DSP core
• Enhanced direct-memory-access
controller 3 (EDMA3)
• 128K-byte RAM shared memory
• Two external memory interfaces
• Three configurable 16550 type UART
modules
• LCD controller
• Two serial peripheral interfaces (SPI)
• Multimedia card (MMC)/secure digital (SD)
• Two master/slave inter-integrated
circuit
• One host-port interface (HPI)
• USB 1.1 OHCI (Host) with integrated
PHY (USB1)
LCD
LCD
Controller
Controller
128KB
RAM
Switched Central Resource (SCR) / EDMA
Peripherals
10/
100
EMAC
HPI
USB
1.1
USB2.0
Applications
• Medical measurement
• Industrial diagnostics
McASP
(3)
I2 C
(2)
MMC/SD
(1)
WD
Timer
(2)
eQEP
(2)
eCAP
(3)
PWM
(3)
External Memory Interfaces
Serial Interfaces
SPI
(2)
Control Timers
Connectivity
UART
(3)
EMIFB
SDRAM
32 -bit
EMIFA
NAND /
SDRAM
16-bit
OMAP-L137 block diagram.
Medical Applications Guide
35
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Complete Analog Front End for ECG/EEG Applications
ADS1298
Get datasheets, samples and evaluation modules at: www.ti.com/sc/device/ADS1298
View the ADS1298 video at: http://e2e.ti.com/videos/m/analog/134732.aspx
Key Benefits
• Reduce components and board size
by 95%
• 1mW/channel reduces solution
power by 95%
• Single-chip solution increases system reliability and patient mobility
Key Features
• Eight low-noise PGAs
• Eight high-resolution, simultaneous
sampling ADCs
• Integrated amplifier for right-leg drive
• Integrated amplifiers for Wilson
Central Terminal (WCT) and
Goldberger Central Terminals (GCT)
• Digital pace detection capability
• Continuous lead-off detection
• Onboard oscillator and reference for
smaller footprint and low-power
applications
Applications
• ECG and EEG applications
Medical Applications Guide
The eight-channel, 24-bit ADS1298 is the first in a family of fully integrated analog
front ends (AFEs) for patient monitoring, portable and high-end electrocardiogram
(ECG) and electroencephalogram (EEG). Succeeding four- and six-channel versions
and 16-bit versions offer designers a migration path to varying resolutions and
channel combinations for low-noise medical equipment. Examples include patient
monitors, rest and stress ECG, fetal monitoring, hospital and public access AEDs,
as well as sports and fitness monitors. ADS1298
REF
PGA1
ADC1
PGA8
ADC8
MUX
RLD
Wilson
Lead Off
Temperature
Test
Respiration
SPI
and
Control
Oscillator
Pace
Detect
ADS1298 block diagram.
36
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Low-Noise, 900kHz, 50µV, RRIO Precision Op Amps
OPA378, OPA2378
Get samples and datasheets at: www.ti.com/sc/device/OPA378 or www.ti.com/sc/device/OPA2378
Key Features
Applications
• Low noise 0.1Hz to 10Hz: 0.4µVPP
• Low offset voltage: 15µV (typ)
• Quiescent current: 125µA (typ)
• Offset drift: 0.1µV/°C (typ)
• Single-supply operation
• Supply voltage: 2.2V to 5.5V
• EMI input filters and RRIO
• Packaging: SC70-5, SOT23-5
• Battery-powered instruments
• Medical instrumentation
• Temperature measurement
• Handheld test equipment
The OPA378 (single) and OPA2378
(dual) represent a new generation of
micro­power op amps featuring a combination of rail-to-rail I/O, low input
offset voltage (50µV (max)), low quiescent current and 90kHz bandwidth. It
has excellent PSRR which makes it an
ideal choice for applications that run
direct from batteries without regulation. 100nV/div
Voltage Noise (nV/√Hz)
100
10
1
Time (1s/div)
1
10
100
1k
Frequency (Hz)
10k
30k
OPA378: voltage noise spectral density
versus frequency.
OPA378: 0.1Hz to 10Hz noise.
Zerø-Drift, Low-Offset, Single-Supply Op Amps
OPA334, OPA335
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/OPA334
or www.ti.com/sc/device/OPA335
Key Features
• GBW: 2MHz
• Low offset voltage: 5µV (max)
• Zero drift: 0.05µV/°C (max)
• Quiescent current: 285µA
• EMI input filtered
• Shutdown available on OPA344
• Packaging: SOT23-5, SOT23-6,
SO-8, MSOP-10 (dual)
The OPA334 and OPA335 CMOS op amps use auto-zeroing techniques to simultaneously provide very low offset voltage and near-zero drift over time and
tem­perature. These high-precision amps offer high input impedance and rail-to-rail
output swing.
VEX
R1
+5V
R
R
R
R
VOUT
OPA335
Applications
• Transducer applications, such as
pressure sensing
• Electronic weight scales
• Temperature measurement
Medical Applications Guide
R1
VREF
OPA335 –5V supply bridge amplifier for high CMRR
37
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Precision, Rail-to-Rail I/O Instrumentation Amplifier
INA326
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/INA326
Key Features
• Low offset: 100µV (max)
• Low offset drift: 0.4µV/°C (max)
• Excellent long-term stability
• Very low 1/f noise
• Input common-mode range: 200mV
below negative rail to 100mV above
positive rail
• Wide output swing: Within 10mV of
rails
• Single supply: +2.7V to +5.5V
• Packaging: MSOP-8, MSOP-10
The INA326 is a precision instrumentation amplifier with rail-to-rail input and
output and with true single-supply operation it offers very low DC errors and
input common-mode ranges that extend beyond the positive and negative rails. Excellent long-term stability and very low 1/f noise assure low offset voltage and
drift throughout the life of the product.
V+
Applications
• Medical instruments
• Multi-channel data acquisition
systems
• Low-level transducer amplifier for
bridges, load cells, thermocouples
• Wide dynamic range sensor
measurements
VIN–
2
1
R1
VIN+
V-
7
4
6
INA326
8
3
5
R2
VO
G = 2(R2/R1)
C2
INA326 functional block diagram.
4-/8-Channel, 16-Bit, Serial Output ADC for Portable Applications
ADS8331, ADS8332, ADS8341, ADS8342, ADS8343, ADS8344, ADS8345
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with ADS8331, ADS8332, ADS8341, ADS8342, ADS8343, ADS8344 or ADS8345)
Key Features
• Conversion rate: up to 100kHz
• 4-/8-channel single-ended or
2-channel differential input
• SINAD: 86dB
• Serial interface
• Single supply: 2.7V to 5V
• Packaging: SSOP-16
The ADS8341 is a 4-channel, 16-bit ADC with synchronous serial interface. Typical
power dissipation is 8mW at a 100kHz throughput rate and a +5V supply. The reference voltage can be varied between 500mV and VCC, providing a corresponding
input voltage range of 0V to VREF. It is tested down to 2.7V operation. The serial
interface also provides low-cost isolation for remote data acquisition.
SAR
DCLK
Applications
• Portable medical devices
• Test and measurement
• Data acquisition
CH1
CH2
CS
Comparator
CH0
Four
Channel
Multiplexer
CDAC
CH3
Serial
Interface
and
Control
SHDN
DIN
DOUT
BUSY
COM
VREF
ADS8341 functional block diagram.
Medical Applications Guide
38
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Multi-Channel, 24-Bit, Delta-Sigma ADCs
ADS1271, ADS1274, ADS1278
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with ADS1271, ADS1274 or ADS1278)
Key Features
• Single-channel or simultaneously
measures 4/8 channels
• Up to 128kSPS data rate
• AC performance:
• Bandwidth: 62kHz
• SNR: 111dB (high-resolution mode)
• THD: –108dB THD
• DC accuracy:
• Offset drift: 0.8µV/°C
• Gain drift: 1.3ppm/°C
• Linear-phase digital filter
• SPI or frame-sync serial interface
• Analog supply: 5V
• Packaging: HTQFT-64 PowerPAD™
The ADS1271, ADS1274 and ADS1278 are single-, quad- and octal-channel ADCs,
respectively. These 24-bit, delta-sigma ADCs have data rates of up to 128kSPS,
allowing simultaneous sampling of all channels, and are offered in identical packages for drop-in expandability. The devices offer excellent DC and AC specifications for high-precision measurement applications. They provide a usable signal
bandwidth of up to 90 percent of the Nyquist rate with less than 0.005dB of ripple. Four operating modes allow for optimization of speed, resolution and power.
VREFP VREFN
DVDD
SYNC/PDWN
MODE
Control
Logic
CLK
AINP
∆Σ
DRDY/FSYNC
SCLK
DOUT
DIN
FORMAT
Serial
Interface
Digital
Filter
Modulator
AINN
Applications
• Pressure sensors
• Patient monitoring
• Vibration/modal analysis
• Multi-channel data acquisition
• Acoustics/dynamic strain gauges
AVDD
AGND
DGND
ADS1271/4/8 functional block diagram.
Single, Dual and Quad Fully Differential Amplifiers
THS4521, THS4522, THS4524
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with THS4521, THS4522 or THS4524)
Key Features
• Low quiescent current: 1.14mA (typ)
• Power down capability: 20μA (typ)
• Input voltage noise: 4.6nV/√Hz
• Slew rate: 490V/µs
• Neg. rail-input and rail-to-rail output
• Power supply voltage:
+2.5V (±1.25V) to +5.5V (±2.75V)
• Packaging1: SO-8 and MSOP-8
(THS4521), TSSOP-16 (THS4522)
and TSSOP-38 (THS4524)
Applications
• Portable medical equipment
• Low power SAR and delta-sigma
ADC drivers
• Low power differential driver
• Low-power differential signal
conditioning
Medical Applications Guide
The THS4521(single), THS4522 (dual), and THS4524 (quad) are negative rail input, railto-rail output, fully differential amplifiers operating from a single +2.5V to +5.5V supply. The low 1.14mA/channel quiescent current and power down capability to 20µA make it
a good choice for low power applications. The output common-mode control with low
offset and drift allows for dc-coupling in high accuracy data acquisition systems.
1k
1.5nF
5V
VIN+
49.9
1k
+
AINN1
–
THS4521
VIN–
–
1k
+
49.9
ADS1278: Ch1
2.2nF
AINP1
VCOM
VOCM
x1
0.1µF
1.5 nF
0.1µF
OPA2350
1k
THS4521 driving one channel of ADS1278 .
39
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Electrocardiogram (ECG) Analog Front End Module for the C5515 ECG Medical Development Kit
TMDXMDKEK1258
Get samples, datasheets and evaluation modules at: www.ti.com/tmdxmdkek1258
Key Features
• ECG AFE module key components
• ADS1258: 16-channel, 24-bit
sigma delta analog-to-digital converter (ADC)
• INA128: precision, low power
instrumentation amplifier
• PCA9535: remote 16-bit I2C and
SMBus low-power I/O expander
• TLV3404: nanopower open drain
output comparator
• REF5025: low-noise, very low drift
precision voltage reference
• ECG MDK system features
• Based on industry’s lowest power
DSP processor – TMS320C5515
• 12-lead ECG output using 10
electrode input
• 0.05Hz to 150Hz bandwidth
• Leads off detection
• Real-time 12-lead ECG waveform
display on EVM LCD, one lead at a
time
• Real-time 12-lead ECG waveform
display on PC, three leads at a
time
• Heart beat rate display
• Recording of ECG data, and offline
display option of recorded ECG
data
To reduce the time to market for medical device companies, TI has launched a set of medical application development tools with complete signal chain designs
and software for electrocardiograms, digital stethoscopes, and pulse oximeter
products. Each of the three medical development kits (MDKs) is comprised by purchasing an analog front-end (AFE) module with specific circuitry design optimized for each end product plus a TMS320C5515 DSP Evaluation Module (EVM)
based on the industry’s lowest power DSP – TMS320C5515. MDKs provide a great evaluation platform to help medical device manufacturers focus on product
differentiation, like algorithm development and feature enhancement. Applications
TMDXMDKEK1258 EVM .
The TMDXMDKEK1258 Electrocardiogram (ECG) Analog Front End (AFE) module
is part of the ECG medical development kit (MDK) that consists of the ECG AFE
module, a processor board (C5515 DSP evaluation module), a set of collateral and
C5515 based application sample code to implement the ECG application. The
ECG MDK delivers a complete signal chain solution to enable ECG developers to
build a complete ECG system quickly for evaluation and get to production faster.
• Portable ECG devices
• Patient monitoring
A new ECG Analog Front End module is also now available using the latest
ECG ADC – the ADS1298. The P/N for this is ADS1298ECGFE-PDK and it can
be used seamlessly with the C5515 EVM (TMDXEVM5515). MDK ECG SW is freely available at: http://code.google.com/p/c5505-ezdsp/
Medical Applications Guide
40
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers
INA118
INA121
INA126
INA128
OPA277
INA326
*Page 38
INA333
OPA130
OPA333
OPA334/5
*Page 37
OPA336
OPA378
*Page 37
OPA2378
*Page 37
Instrumentation
Amp
Instrumentation
Amp
Instrumentation
Amp
Instrumentation
Amp
Op Amp
Instrumentation
Amp
Instrumentation
Amp
FET-Input
Amplifier
Precision Op Amp
Op Amp
110dB CMRR, 5nA (max) bias current, 50µV (max) offset
Wide BW at high gain, ±1.35V to ±18V supply
INA128, INA121
106dB CMRR, 4pA (max) bias current, 200µV (max) offset
Low input bias current
INA126
175µA/ch supply, 3µV/°C (max) drift, 250µV (max) offset
Precision low power, ±1.35V to ±18V supply
INA2126
120dB CMRR, 5nA (max) bias current, 50µV (max) offset
High CMRR, wide BW at high gain, ±2.25V to ±18V
supply
High precision, low drift, low power
INA129
10µV offset, ±0.1µV/°C drift, 134dB open-loop gain
120dB CMRR (G = 100), 100µV (max) offset, 0.4µV/°C
(max) drift
25μV (max) offset, 50nV/°C drift, 50μA (typ) Iq
20pA (max) bias current, 90dB (min) CMRR, 1MHz BW
1.8V min supply, 0.017mA/ch (max), 10μV offset (max),
0.05μV/°C drift (max)
2MHz, 5µV (max) offset, 0.05µV/°C (max) drift, 285μA
High CMRR, low cost, +2.7V to +5.5V
Best offset/noise combination, supply down to 1.8V,
low power
Precision, low input bias, low power
Zero drift, high precision, low power, EMI input
Provides very low offset voltage and near-zero drift
over time and temperature; SOT23
micoPower, SOT23 package
Lowest noise, power, price, precision zero-drift option
OPA2277 (dual)
OPA4277 (quad)
INA321, INA333
INA326, INA321
OPA131, OPA137
OPA335, OPA378,
OPA330
OPA735, OPA333,
OPA334
OPA379
OPA330, OPA333
Op Amp
Low Noise
Precision Op Amp
Precision Op Amp
125µV (max) offset, 1.5µV/°C drift, 20µA supply
0.1µV/°C Vos drift, 125µA, 900kHz, 0.4μVPP (0.1Hz to
10Hz) 0.4µ Vpp (0.1Hz to 10Hz), 0.9MHz
2.2V to 5.5V supply, 20µV voltage, 0.1µV/°C drift, 125µA
quiescent current
Low Power FDA
1.14mA quiescent current (typ), 4.6nV/√Hz voltage noise,
2.5V to 5.5V supply
ADS1258
Delta-Sigma ADC
16-channel, 24-bit, 125kSPS, 23.7kSPS/channel
ADS1271/74/78
*Page 39
ADS1298
*Page 36
ADS8317
Delta-Sigma ADC
24-bit, 128kSPS, 8-channel, 111dB SNR
ECG/EEG AFE
24-bit, 8 PGA, 8 ADC, plus RLD and RESP
SAR ADC
ADS8326
ADS8331/32
*Page 38
ADS8341/2/3/4/5
*Page 38
ADS8519
DDC112
Low-Power ADC
SAR ADC
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max)
INL, differential input
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max) INL
16-bit, 500kSPS, 4/8 channels, with serial interface
Serial Output
ADC
High Volt. SAR ADC
Charge-Digitizing
ADC
16-bit, 4-/8-channel single-ended or 2-channel
differential input, 2.7V to 5V single supply ADC
16-bit, 250kSPS, 1.5LSB (max) INL, 92dB SNR
Dual current input, 20-bit ADC, ±0.005% INL reading
±0.5ppm FSR
REF02
REF102
Precision VREF
10V, Ultra
Precision
0.2% (max) initial accuracy, 10ppm/°C (max) drift, 1.4mA (max)
0.05% (max) initial accuracy, 2.5ppm/°C (max) drift,
1.4mA (max)
REF30xx
Low-Power,
Low-Drift Ref.
50µA, 0.2% initial accuracy, 50ppm/°C max drift, ±25mA
output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
REF32xx
Ultra-Low-Drift
Series Reference
100µA, 0.2% initial accuracy, 7ppm/°C max drift,
±10mA output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
Improves system accuracy
REF33xx
Very Low-Power
Series Reference
5µA, 0.15% initial accuracy, 30ppm/°C max drift,
±5mA output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V, 3.3V
Preserves battery life, fits into physically constrained
systems
REF30xx, REF31xx,
REF29xx
REF5010
10V, High-Precision, 0.05% initial accuracy, 3ppm/°C max drift, ±10mA
Very Low-Drift
output, 10V
Series Reference
Improves system accuracy
REF102
REF50xx
High-Precision,
Very Low-Drift
Series Reference
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 2.048V, 2.5V, 3.0V, 4.096V, 4.5V, 5.0V
Improves system accuracy
REF02
THS4521/22/24
*Page 39
Has excellent PSRR which makes it an ideal choice
for applications that run direct from batteries without
regulation
Low power, low noise enables high accuracy
Data Converters
Fastest multi-channel, delta-sigma ADC, measures
all 16 inputs in <675µs
Simultaneous measurement, onboard decimation
filter
Complete front end, reduction in power and size,
increase reliability
Low power, small package, and wide supply range
ADS1256, ADS1255,
ADS8344
ADS1294, ADS1296,
ADS1198, ADS1258
ADS8326
Small package, wide supply range
Mux out feature can be used to reduce system part
count and overall cost
Easy to use
ADS8342
Single supply, high voltage inputs
High precision, true integrating function
ADS8515
DDC114, DDC118,
DDC232
Excellent line/load regulation, low noise
Excellent stability and line/load regulation
REF5050
REF5010
References
New products are listed in bold red.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
REF31xx, REF33xx,
REF29xx
41
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
MSP430F20xx
Ultra-Low-Power
16-bit MCU
1KB/2KB Flash, 128B RAM, SPI+I2C 16-bit MCU
8 ch. 12-bit ADC or 4 ch. 16-bit SD ADC, 4 x 4mm
package
MSP430F22x4
Ultra-Low-Power
16-bit MCU
8 to 32KB Flash, 512B/1KB RAM, SPI + I2C + UART/LIN
+ IrDA
12 ch. 10-bit ADC, 2 operational amplifiers
MSP430F23x0
Ultra-Low-Power
16-bit MCU
8 to 32KB Flash, 1KB/2KB RAM, SPI + I2C + UART/LIN
+ IrDA
Analog comparator, HW multiplier
MSP430F41x
Ultra-Low-Power
16-bit MCU
4 to 32KB Flash, 256B to 1KB RAM, SVS,
96 segment LCD
Analog comparator
MSP430F42x
Ultra-Low-Power
16-bit MCU
8 to 32KB Flash, 256B to 1KB RAM, SPI + UART, SVS,
128 segment LCD
3 x 16-bit SD ADC
MSP430F42x0
Ultra-Low-Power
16-bit MCU
16 to 32KB Flash, 256B RAM, 56 segment LCD
5 ch. 16-bit SD ADC, 12-bit DAC
MSP430F43x
Ultra-Low-Power
16-bit MCU
16 to 32KB Flash, 512B/1KB RAM, SPI + UART, SVS,
160 segment LCD
8 ch. 12-bit ADC, analog comparator
MSP430F44x
Ultra-Low-Power
16-bit MCU
32 to 60KB Flash, 1KB/2KB RAM, 2x SPI + UART, SVS,
160 segment LCD
8 ch. 12-bit ADC, HW multiplier
MSP430F47xx
Ultra-Low-Power
16-bit MCU
60KB Flash, 256B RAM, (4) USCI, 160 segment LCD
(4) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
MSP430F241x
Ultra-Low-Power
16-bit MCU
120KB Flash, 8KB RAM, (4) USCI, SVS, temp. sensor
8 ch. 12-bit ADC, analog comparator, HW multiplier
MSP430F261x
Ultra-Low-Power
16-bit MCU
120KB Flash, 8KB RAM, (4) USCI, SVS, DMA, temp.
sensor
Analog comparator, 2 ch. 12-bit DAC, 8 ch. 12-bit
ADC, HW multiplier
MSP430F471xx
Ultra-Low-Power
16-bit MCU
120KB Flash, 8KB RAM, (4) USCI, DMA 160 segment LCD
(7) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
MSP430F54xxA
Ultra-Low-Power
16-bit MCU
128 to 256KB Flash, 16KB RAM, (4) USCI, PMM, DMA,
temp. sensor
16 ch. 12-bit ADC, analog comparator, RTC, internal
voltage regulator for power optimization
MSP430FG42x0
Ultra-Low-Power
16-bit MCU
16 to 32KB Flash, 256B RAM, 56 segment LCD
5 ch. 16-bit SD ADC, 12-bit DAC, 2 integrated
op amps
MSP430FG43x
Ultra-Low-Power
16-bit MCU
32 to 60KB Flash, 1KB/2KB RAM, SPI + UART, SVS,
128 segment LCD
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, DMA, 3 op amps
MSP430FG461x
Ultra-Low-Power
16-bit MCU
92 to 120KB Flash, 4KB/8KB RAM, SPI + I2C + UART/LIN
+ IrDA, 160 LCD
12 ch. 12-bit ADC, 2 ch.12-bit DAC, A-comp, 3 op
amp, HW multiplier
MSP430FG47x
Ultra-Low-Power
16-bit MCU
32 to 60KB Flash, 2KB RAM, SPI + I2C + UART/LIN +
IrDA, 128 LCD controller
5 ch. 16-bit SD ADC, 2 ch. 12-bit DAC,
comparator_A, 2 op amps
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L137
*Page 35
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
OMAP-L138
TMS320C5000™
DSP
Power efficient, high performance
TMS320F28x™
32-Bit MCU
TMS320F2802x/3x
Piccolo™
32-Bit
Microcontroller
32-bit architecture, fixed- or floating-point code, up to
225MIPS operation
Up to 60MHz C28x™ core with optional control law
accelerator. Up to 128KB Flash, high resolution (150ps)
PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
TMS320F2823x,
TMS320F2833x
TMS320F283x
Delfino,
TMS320F280x
TMS320F283x
Delfino™
32-Bit
Floating-point
Microcontroller
Up to 300MHz C28x™ core. Up to 512KB Flash, high
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN, QEP,
external memory bus, DMA.
TMS320VC5506
DSP
200MHz, dual MAC, very low stand-by power of 0.12mW
Microcontroller integration, real-time control
performance
With dedicated, high precision peripherals, Piccolo
microcontrollers are the ultimate combination of
performance, integration, size, and low cost. Ideal for
precision sensing and control applications.
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point brings
increased performance and quicker development.
Ideal for precision sensing and control applications.
Supported by eXpressDSP™ and many other
software packages and tools
TMS320F2802x/3x
Piccolo,
TMS320F280x
TMS320VC5509A,
TMS320VC5502
Power Management
bq20z90-V110
bq24703
bq24721C
Battery Fuel
Gauge
Battery Charger
Battery Charge
Management
Instant accuracy better than 1% error over lifetime of the
battery
0V operation, ±0.4% charge voltage accuracy, integrated PWM
Multi-chemistry and multi-cell sync switch-mode charger
bq20z70, bq20z80
bq24702, bq24705
New products are listed in bold red.
additional product information see designated page number.
*For
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Automatically adjusts for battery aging, battery self
discharge and temperature inefficiencies
Dynamic power management, multichemistry
High efficiency, pack and system protection functions
42
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
bq29330
Battery Safety
Battery pack full-protection analog front end
DCH010505D
1W, 3kV isolation, minimal external components
TPS65130
TPS717xx
TPS718xx-yy
TPS780xx
Galvanic Isolated,
DC/DC Conv.
Load Switch with
Controller Turn-On
Current Limited
Load Switch
Voltage Supervisor
DC/DC Converter
Boost Converter
with Bypass
Switch
Step-Down
Converter
Step-Down Conv.
Dual Output
Step-Down Conv.
Buck-Boost
Converter
Boost Converter
Single-Channel LDO
Dual-Channel LDO
LDO with DVS
TPS79901
Single Channel LDO
Very high rejection of power-source noise
CC1101
Sub-1GHz RF
Transceiver
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Wake-on-radio functionality; integrated packet handling
with 64B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2 to 500kbps; extremely fast PLL turn-on/hop time
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temperature
range; AES-128 security module
Ideal for low-power systems; any low-end MCU
can be used; backwards compatible with existing
systems; suitable for fast frequency-hopping systems
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal for
industrial applications; no external processor needed
for secure communication
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
MCU, Flash and RAM in one package; four flexible power
modes for reduced power consumption; includes CC1101
transceiver frequency synthesizer; built-in AES-128
encryption coprocessor
Excellent RX sensitivity, low power, easy to use
development tools
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication
RF design System-on-Chip for quick time to market.
Provides a robust and complete ZigBee USB dongle
or firmware-upgradable network node
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity, selectivity
and blocking performance
Fast-to-market Bluetooth® low energy compliant
solution
Single-chip 802.11b/g/n WLAN and Bluetooth® solution
using TI’s digital radio processor technology using a
single antenna.
Single-chip 802.11a/b/g/n WLAN and Bluetooth® solution
using TI's digital radio processor technology using a
single antenna.
Sophisticated low-power technology ideal for battery operated
solutions; coexistence features enable simultaneous WLAN and
Bluetooth® operations; supports ANT+ standard.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
Second
Generation
Z-Stack™
Network Processor
ZigBee stack and radio in one chip; implements ZigBee
certified stack; configurable device type and network
settings; excellent selectivity and blocking performance
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery operated systems; excellent
coexistence with Bluetooth® technology and Wi-Fi.
ECG Analog Front
End Module for
the C5515 ECG
Medical Dev. Kit
12-lead ECG output using 10 electrode input; 0.05Hz to
150Hz bandwidth; leads off detection; heart beat rate
display
Based on industry’s lowest power DSP processor –
TMS320C5515
TPS22902
TPS22946
TPS3808Gxx
TPS54350
TPS61097-33
TPS62110
TPS62230
TPS62400
TPS63030
Low on resistance, controlled turn-on, ultra small 0.64mm2
package, quick output discharge
Configurable current limit, ultra-small package, 1µA
quiescent current at 1.8V
Low quiescent current, programmable-delay
4.5 to 20VIN 3A DC/DC w/integrated switch FET, sync pin, enable
Highly efficient, operates down to 0.3V; bypass switch; 5nA
shutdown current; SOT-23
3.1V to 17V VIN, 1.5A conversion, synchronization pin, low
battery indicator, power save mode
Up to 90dB PSRR, excellent AC and transient load regulation
180° out of phase operation, serial interface
1A switch, automatic transition between step down and
boost mode
800mA switch, adjustable, dual output, positive/negative boost
Very high rejection of power-source noise
Very high rejection of power-source noise
Dynamic voltage scaling (DVS) with low IQ 500nA
Provides individual cell voltages and battery voltage
to battery management host
Safety isolation, removal of ground loops
Ultra-small, fully integrated solution
Ultra-small, low quiescent current current limited switch
DCH010512/15
DCR021205
TPS22901, TPS22922,
TPS22924C, TPS22960
TPS22949, TPS22945
Circuit initialization and timing supervision
Eliminate beat noise/ceramic caps/FPGA/integration
Supper efficient boost, works over entire battery range,
low quiescent current, integrate the bypass switch,
small package
Very low noise/high efficiency
TPS310x
TPS54550
Low noise regulation, 12mm2 solution size
Flexible voltage adjustment for processors and MCUs
TPS62260
TPS62410
Extending application run time, small solution
TPS61020
Two supplies from one switcher
Low-noise power rails for sensitive analog components
Low-noise power rails for sensitive analog components
DVS voltage designed to operate with MSP430 to
increase power savings
Low-noise power rails for sensitive analog components
TPS795xx, TPS799xx
TPS719xx-yy
TPS78101
TPS62050
TPS79501, TPS74301
RF ICs
RF Transceivers
RF Systems-on-Chip
CC2560
CC1110/11
CC2530/CC2531
CC2540
WL1271
WL1273
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Second Gen.
System-on-Chip
2.4GHz IEEE
802.15.4/RF4CE/
ZigBee
2.4GHz Bluetooth®
Low Energy
Compliant RF
System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
CC2500
CC2530
CC2510, CC2511
CC2590/91,
CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Toolkits
TMDXMDKEK1258
*Page 40
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
New products are listed in bold red. Preview products are listed in bold blue.
43
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Overview
Oxi Lvi
MSP430/DSP
Pulse
Rate
LoBatt
DeMUX
The oximeter senses and calculates
the amount of light at those wavelengths proportional to the oxygen
saturation (or desaturation) of the
hemoglobin. The use of light in the
absorbency measurement requires
the designer to have a true “light-tovoltage” conversion using current as
the input signal.
Amplifiers and Processors
The classic resistor-feedback trans­
impedance amplifier and capacitorfeedback switched integrator are suitable for pulse oximetry applications. In either amplifier configuration, the
resulting output voltage is read by an
analog-to-digital converter and serialized for the MSP430™ microcontroller
or TMS320™ DSP for processing.
Processor selection should be based
on signal-processing needs. TI has a
wide variety of MSP430 products offering up to 25MIPS performance and
extensive mixed-signal integration. For mid-range to high-end systems
requiring much higher digital signal
performance for enhanced signal conditioning and processing, low-power
DSP processors such as C55x™ can
be used. These processors offer higher
than 100MIPS at very low power.
Medical Applications Guide
ADC12
LED
Select
Probe Connector
Red LED Gain
Psuedo
Analog Ground
Infrared LED Gain
Cable
Pin Diode
Red LED ON/OFF
Infrared LED ON/OFF
Light sources, typically light-emitting
diodes (LEDs), shine visible red and
infrared light. Deoxygenated hemo­
globin allows more infrared light to
pass through and absorbs more red
light. Highly oxygenated hemoglobin
allows more red light to pass through
and absorbs more infrared light.
DAC12_1
DAC12_0
The pulse oximeter measures blood
oxy­genation by sensing the infrared
and red-light absorption properties of
deoxy­genated and oxygenated hemoglobin. The oximeter is comprised of a
sensing probe that attaches to a patient’s
ear lobe, toe or finger and is connected
to a data acquisition system for the
calculation and display of oxygen saturation level, heart rate and blood flow.
G1
TransImpedance
Amplifier
Pin Diode
Infrared LED
OA0
Red LED
I
R
R
2nd
Stage
G2
MUX
OA1
I
R
Apart from the MCU and four transistors, only passive components are needed for
this design.
Low-End Portable Pulse Oximeter
For low-end designs, TI’s highly integrated MSP430FG437 reduces the
number of external components. The
design of a non-invasive optical pulse
oximeter using the MSP430FG437
microcontroller (MCU) consists of a
peripheral probe combined with the
MCU displaying the oxygen saturation
and pulse rate on an LCD glass. In this
application, the same sensor is used for
heart-rate detection and pulse oximetry.
The probe is placed on a peripheral
point of the body, such as a fingertip,
an ear lobe or the nose. The probe
includes two LEDs — one in the visible
red spectrum (660nm) and the other
in the infrared spectrum (940nm). The
percentage of oxygen in the body is
determined by measuring the intensity
from each frequency of light after it is
transmitted through the body. Then,
the ratio between these two intensities
is calculated.
The diagram below demonstrates the
implementation of a single-chip, portable pulse oximeter using the ultra-lowpower capability of the MSP430 MCU. 20Ω
P2.2
5kΩ
5
1kΩ
MS430FG437
DAC0
Probe
Integrated
LEDs
Infrared
Visible Red
10
P2.2
1kΩ
5kΩ
20Ω
LED drive circuit.
44
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
necessary, there is a need for higherperformance processors and high-
precision analog components that
provide lower system power.
Because of the high level of analog
integration, the number of external
components is kept to a minimum. Keeping ON time to a minimum and
power cycling the two light sources
also reduces power consumption.
For example, several sources of interference such as neon lamps, UV lamps
and other light emitters may influence
the optical path between LEDs and the
photoreceiver, affecting measurement
accuracy. There could also be signal
distortion caused by motion that
Mid-Range and High-End
Applications
For mid-range and high-end applications where higher performance and
higher measurement accuracy are
occurs while the reading is taken. Sophisticated DSP technology can be
applied to eliminate or reduce these
effects and extract the vital signal of
interest. Often, these DSP technologies require high-sample-rate signalprocessing operations such as demodulation, digital filtering, decimation, and
frequency-domain analysis, which can
be efficiently mapped to a C55x™
low-power digital signal processor.
Operator/Patient Feedback and Monitors
Oxi Lvi
Analog Front End
Photodetector
Pulse
Rate
LoBatt
ADC
Backlight
Filter
REF
Processor
Clock
Keypad
Touch Screen
Control
Audio
Alerts
DAC
LED
Drivers
DAC
Core and
I/O Power
Level Shift
SDRAM
Power Options
Battery
Management
ESD
System
Power
SDRAM
AC/DC
Adaptor
Interface
Battery
Memory
Power
Memory
LEGEND
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Pulse oximeter system block diagram.
Medical Applications Guide
45
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Signal Acquisition Challenges
The resistor-feedback amplifier circuit
is the most common bioelectric trans­
impedance circuit. With the amplifier
used in the inverting configuration,
the light shining on a photodiode produces a small current that flows to the
amplifier sum10MΩ
ming junctions
and through
the feedback
OPA353
VO
resistor. Given Photodiode
the very large
feedback
resistor value, this circuit is extremely
sensitive to changes in light intensity. For example, an input light signal of
just 0.001µW can produce a full-swing
output.
Depending on design requirements, it
can be very useful to achieve output
swing down to or below ground. The
auto-zero transimpedance amplifier
configuration shown in Figure A at right
allows swing to ground, while the one
in Figure B allows swing very close to
ground. A pull-down resistor tied to
–5V allows swing slightly below ground
to minimize errors as the output gets
very close to 0V.
TI’s OPA380 is a monolithic combination of the high-speed OPA355 and
auto-zero OPA335 amplifiers. It offers
a 90MHz gain-bandwidth product and
performs well as a 1MHz transimpedance amplifier with extremely high
precision (25µV maximum offset and
0.1µV/°C maximum drift).
Depending on design requirements,
the switch integrator can be a very
effective solution. TI’s IVC102 does
not have the thermal noise of a feedback resistor and does not suffer from
stability problems commonly found
in transimpedance amps with a large
feedback resistor.
Additionally, IVC203 allows for
synchronized sampling at
an integer multiple of the
AC line frequency, giving
extremely high noise rejection. Transimpedance gain can be
easily changed by extending or
shortening integration time with
switch S2.
A. Dual Supply
IIN
R1
REF3140
+2.5V
Photodiode
–2.5V
ADS8320
OPA340
or OPA350
C1
1MΩ
+2.5V
R2
Transimpedance Amplifier
OPA335
Requirements
• Low input bias current over
–2.5V
temperature range of interest
• Low input capacitance relative to photodiode capacitance
• High gain-bandwidth product
B. Single Supply
• Low voltage noise
IIN
R1
• For maximum precision, low
+5V
offset drift over temperature
• For single-supply systems:
Photodiode
OPA340
• Rail-to-rail input (including
or OPA350
OV) and output if operating
the photodiode in photoC1
1MΩ
voltaic (zero-bias) mode
+5V
• Rail-to-rail output only if
R2
operating the photodiode
OPA335
in photoconductive mode
(biased)
40kΩ*
• Shutdown and/or low
*Optional pull-down resistor to
allow below ground output swing. –5V
supply current if batterypowered system
C2
REF3140
ADS8320
C2
RF
+5V
OPA380
VO
0V to 4.9V
Photodiode
CDIODE
–
20mV
RP
+
1MΩ
(Optional
Pulldown
Resistor)
67pF
–5V
100
kΩ
75pF
Using one photodiode with two
IVC102s eliminates dark current and
ambient light errors, since errors
common to both can be subtracted. Medical Applications Guide
46
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Design Hints
A small (<1pF) capacitor in the feedback loop (CF) controls gain-peaking
caused by diode capacitance. Noise
(voltage-output fluctuation) is caused
by resistor noise, amplifier and current
noise, and environmental noise pickup
(e.g., 50Hz or 60Hz line noise). To minimize noise in the circuit, the designer
should choose a low-noise amplifier,
select the largest practical feedback
resistor, RF shield the amplifier inputs,
include low-pass filtering and use good
PCB layout techniques.
VB
Mid-Range Solution Advantages
• Single-chip solution
• High resolution
• Low noise
• Wide input range by adjustable integration time
• No need for DC corrections of the
diode current
Note: “Pulse Oximeter Design using
MSP430FG43x” (slaa274)
www-s.ti.com/sc/techlit/slaa274
Medical Applications Guide
C1
60pF
C3
C2
5
4
14
30pF
10pF
S2
3
IIN
10
2
VO
S1
1
9
Photodiode
11
Analog
Ground
If the photodiode shunt resistance is
much larger than that of the feedback
resistor, offset voltage is not significant. If offset voltage stability is paramount,
an auto-zero solution including the
OPA335 is best.
To achieve the highest precision levels,
system designers should choose the
OPA380. Designed to meet exacting
transimpedance application requirements, the OPA380 provides an
unbeatable combination of speed
(85MHz GBW over 1MHz transimpedance bandwidth) and precision (25µV
maximum offset, 0.1µV/°C drift and low
1/f noise). A discrete alternative is to use
the OPA365, OPA350, or OPA355, adding the OPA335 in the integrators-
stabilized transimped­ance configuration for circuits requiring low offset and drift. Adding the OPA335 integrator to a
basic transimpedance amplifier will also
reduce its very low frequency noise.
V+
IVC102
6
12
13
S1
Logic Low S2
Closes Switches
Positive or Negative
Signal Integration
V–
Digital
Ground
VO =
–1
C INT
∫I
IN (t) dt
0V
Hold
Integrate
Hold
Reset
S1
S2
High-End Solution Advantages
• Very high resolution
• High noise immunity due to differential input
• High noise immunity due to synchronization on AC supply possible
• High noise immunity due to free
access on integration and reset
switches by software
• No need for DC correction of the
diode currents
• Huge input range can be covered
(>24-bit) due to free programmable
integration times
IVC102a
S2a
S1a
ADC
VREF
S2b
Red and IR
S1b
VREF
MSP430
or
DSP
ADS1255
IVC102b
High-end solution block diagram.
47
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Dual, Current-Input, 20-Bit Charge Digitizing ADC
DDC112
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/DDC112
Key Features
• Single-chip solution for measuring
photodiodes
• High precision, true integrating
function
• Low noise: 3.2ppm, rms
• Outstanding linearity: ±0.005% INL
reading ±0.5ppm FSR
• Programmable full-scale: 50 to
1000pC
• Single supply: +5V supply
• Packaging: SO-28, TQFP-32
The DDC112 is a dual input, wide dynamic range, charge-digitizing ADC which
allows low-level current output ICs to be connected directly to its inputs. Charge
integration is continuous as each input uses two integrators; while one is being
digitized, the other is integrating. In addition to the internal programmable fullscale ranges, external integrating capacitors allow an additional user-settable,
full-scale range of up to 1000pC. A high-speed serial shift register, which holds
the result of the last conversion, can be configured to allow multiple, cascaded
DDC112s, minimizing interconnections.
AVDD
CAP1A
CAP1A
AGND
VREF
DVDD
CHANNEL 1
DGND
DDC112
DCLK
IN1
CAP1B
CAP1B
Applications
CAP2A
CAP2A
• Blood analysis
• Liquid/gas chromatography
• Direct photosensor digitization
• Infrared pyrometry
Dual
Switched
Integrator
∆Σ
Modulator
CHANNEL 2
IN2
CAP2B
CAP2B
DVALID
DXMIT
DOUT
DIN
Digital
Input/
Output
Digital
Filter
RANGE2
RANGE1
RANGE0
Control
Dual
Switched
Integrator
TEST
CONV
CLK
DDC112 functional block diagram.
—–
1.1nV/√Hz Noise, Low-Power, Precision Op Amp
OPA211, OPA2211
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/OPA211
Key Features
• Input voltage noise: 80nVPP,
0.1Hz to 10Hz
• Low offset voltage: 50µV (max)
• Low offset voltage drift: 0.15µV/°C (typ)
• Supply current: 3.6mA/ch
• Gain bandwidth product: 80MHz (G = 100)
• Slew rate: 27V/µs
• Supply range: ±2.25V to ±18V, +4.5V
to +36V
• Output current: 30mA
• Unity gain stable
• Packaging: Tiny DFN-8, MSOP/SO-8
—–
The OPA211 series achieves very low 1.1nV/√Hz noise density with a supply current of only 3.6mA. It offers rail-to-rail output swing to maximize dynamic range. In precision data acquisition systems, the OPA211 provides <1µs settling time to
16-bit accuracy even for 10V output swings. By combining AC performance with
only 50µV of offset and low drift over temperature, the OPA211 is able to drive fast,
high-precision ADCs or buffer the outputs of high-resolution DACs.
OPA2211
OPA211
NC
1
8
Enable
OUT A
1
–IN
2
7
V+
–IN A
2
+IN
3
6
OUT
+IN A
3
V–
4
5
NC
V–
4
A
B
8
V+
7
OUT B
6
−IN B
5
+IN B
Applications
• Medical instruments
• Portable medical devices
• Ultrasound amplifiers
• Low-noise, low-power signal
processing
Medical Applications Guide
MSOP−8
MSOP−8
Pin configurations.
48
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Pulse Oximeter (PO or SpO2) Analog Front End Module for the C5515 PO or SpO2 Medical
Development Kit
TMDXMDKPO8328
Get samples, datasheets and evaluation modules at: www.ti.com/tmdxmdkpo8328
Key Features
• PO AFE module key components
•ADS8328: low power, 16-bit, 500ksps,
analog-to-digital converter (ADC)
•DAC7573: quad, 12-bit, low power,
voltage output digital-to-analog converter DAC
•OPA381: precision, low power,
transimpedance amplifier (current to voltage converter)
•REF5025: low noise, very low drift,
precision voltage reference
• DS MDK system features
•Based on industry’s lowest power
DSP processor – TMS320C5515
•Display of oxygen level percentage
ranging from zero to 100 percent
•Display of pulse rate, ranging from
20 to 300
•Real-time display of plethysmogram on PC
•Sensor off detection
•Common signal conditioning path
for red and infrared signal
To reduce the time to market for medical device companies, TI has launched a set
of medical application development tools with complete signal chain designs and
software for electrocardiograms, digital stethoscopes, and pulse oximeter products. Each of the three medical development kits (MDKs) is comprised by purchasing an analog front-end (AFE) module with specific circuitry design optimized for
each end product plus a TMS320C5515 DSP Evaluation Module (EVM) based on
the industry’s lowest power DSP – TMS320C5515. MDKs provide a great evaluation platform to help medical device manufacturers focus on product differentiation, like algorithm development and feature enhancement. The TMDXMDKPO8328 Pulse Oximeter (PO or SpO2) Analog Front End (AFE)
module consists of the PO AFE module, a processor board (C5505 DSP evaluation
module), a set of collateral and C5505 based application sample code to implement the PO application. The PO MDK delivers a complete signal chain solution to
enable PO developers to build a complete PO system quickly for evaluation and
get to production faster. Applications
• Pulse oximeters
• Patient monitoring
Component Recommendations
Component
Description
Key Features
Other TI
Solutions
Benefits
Amplifiers
IVC102
OPA141
Transimpedance
Amp
Precision Op Amp
Precision switched integrator
OPA211/2211
*Page 48
OPA334/5
Precision Op Amp
10MHz, 6.5nV/√Hz, ±4.5V to ±18V, 1.8mA typical, FET
input: IB = 20pA max
—
1.1nV/√Hz noise at 1kHz, ±2.25V to ±18V supply, 80MHz BW
Op Amp
2MHz, 5µV (max) offset, 0.05µV/°C (max) drift, 285μA
OPA336
OPA350
OPA353
Op Amp
Op Amp
MicroAmplifier™
Series
Op Amp
Transimpedance
Amp
12V Op Amp
CMOS Op Amp
125µV (max) offset, 1.5µV/°C drift, 20µA supply
OPA363
OPA380
OPA725
OPA726
OPA735
OPA365
Zero-Crossover
Op Amp
Zero-Crossover
Op Amp
OPA827
Unity gain stable, RRO, wide supply range
OPA227, OPA827
Provides very low offset voltage and near-zero drift
over time and temperature; SOT23
micoPower, SOT23 package
OPA735, OPA333,
OPA334
OPA379
500µV VOS, 38MHz, 2.5V to 5V supply
High speed, single supply, rail-to-rail
1.8V, high CMR, RRIO, shutdown
90MHz GBW, over 1MHz transimpedance BW, 25µV offset
(max), 0.1µV/°C drift (max)
Very low noise, high speed, 12V CMOS
4V to 12V, 20MHz GBW, 30V/µs slew rate,
0.0003% (typ) at 1kHz THD+N
2.7V to 12V, 0.75µA (max) IQ/ch, 1.6MHz GBW,
115dB (min) CMRR, RRO
1.8V to 5.5V, 50MHz BW, 25V/µs slew rate, 0.0004% (typ)
THD+N, 4.5nV/√Hz at 100kHz, RRIO
Precision, dynamic range 4 to 5 decades, excellent
long term stability
OPA364
OPA350, OPA335
OPA727
Outstanding ac performance, excellent CMRR, PSRR
Zero-crossover input offers excellent CMRR over
entire input range
Zero-crossover, high speed, low input bias, low noise,
RRIO
New products are listed in bold red.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Reduces noise by averaging the input noise of the
sensor, amplifier, and external sources
Common mode voltage range includes GND
49
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Component Recommendations (Continued)
Component
Description
Key Features
Other TI
Solutions
Benefits
Data Converters
ADS8318
High-Speed SAR
16-bit, 500kSPS, 18mW at 500kSPS power, ±1 LSB INL
Precision, excellent AC/DC performance
ADS8319
ADS8317
SAR ADC
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max)
INL, differential input
Low power, small package, and wide supply range
ADS8326
ADS8326
Low-Power ADC
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max) INL
Small package, wide supply range
DDC112
*Page 48
Dual Current
Input ADC
Wide dynamic range, charge digitizing, 20-bit ADC
Single-chip solution
REF31xx
Low-Drift Series
Reference
0.2% initial accuracy, 15ppm/°C max drift, ±10mA
output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
REF32xx
Ultra-Low-Drift
Series Reference
100µA, 0.2% initial accuracy, 7ppm/°C max drift, ±10mA
output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
Improves system accuracy
REF33xx
Very-Low-Power
Series Reference
5µA, 0.15% initial accuracy, 30ppm/°C max drift, ±5mA
output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V, 3.3V
Preserves battery life, fits into physically constrained
systems
REF30xx,
REF31xx, REF29xx
REF50xx
High-Precision,
Very-Low-Drift
Series Reference
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 2.048V, 2.5V, 3.0V, 4.096V, 4.5V, 5.0V, 10V
Improves system accuracy
REF02
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Applications
Processor
1KB/2KB Flash, 128B RAM, SPI+I2C
8 ch. 12-bit ADC or 4 ch. 16-bit SD ADC, 4 x 4mm
package
12 ch. 10-bit ADC, 2 op amps
References
REF30xx,
REF33xx, REF29xx
Processors
MSP430F20xx
MSP430F22x4
MSP430F23x0
MSP430F41x
MSP430F42x
MSP430F42x0
MSP430F43x
MSP430F44x
MSP430F47xx
MSP430F241x
MSP430F261x
MSP430F471xx
MSP430F54xxA
MSP430FG42x0
MSP430FG43x
MSP430FG461x
MSP430FG47x
OMAP3530
OMAP-L137
Low-Power
Applications
Processor
8 to 32KB Flash, 512B/1KB RAM, SPI + I2C + UART/LIN
+ IrDA
8 to 32KB Flash, 1KB/2KB RAM, SPI + I2C + UART/LIN
+ IrDA
4 to 32KB Flash, 256B to 1KB RAM, SVS,
96 segment LCD
8 to 32KB Flash, 256B to 1KB RAM, SPI + UART, SVS,
128 segment LCD
16 to 32KB Flash, 256B RAM, 56 segment LCD
16 to 32KB Flash, 512B/1KB RAM, SPI + UART, SVS,
160 segment LCD
32 to 60KB Flash, 1KB/2KB RAM, 2x SPI + UART, SVS,
160 segment LCD
60KB Flash, 256B RAM, (4) USCI, 160 segment LCD
120KB Flash, 8KB RAM, (4) USCI, SVS, temp. sensor
120KB Flash, 8KB RAM, (4) USCI, SVS, DMA, temp. sensor
120KB Flash, 8KB RAM, (4) USCI, DMA, 160 segment LCD
128 to 256KB Flash, 16KB RAM, (4) USCI, PMM, DMA,
temp. sensor
16 to 32KB Flash, 256B RAM, 56 segment LCD
Analog comparator
3 x 16-bit SD ADC
5 ch. 16-bit SD ADC, 12-bit DAC
8 ch. 12-bit ADC, analog comparator
8 ch. 12-bit ADC, HW multiplier
(4) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
8 ch. 12-bit ADC, analog comparator, HW multiplier
Analog comparator, 2 ch. 12-bit DAC, 8 ch. 12-bit ADC,
HW multiplier
(7) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
16 ch. 12-bit ADC, analog comparator, RTC, internal
voltage regulator for power optimization
5 ch. 16-bit SD ADC, 12-bit DAC, 2 integrated op amps
32 to 60KB Flash, 1KB/2KB RAM, SPI + UART, SVS,
128 segment LCD
92 to 120KB Flash, 4KB/8KB RAM, SPI + I2C + UART/LIN
+ IrDA, 160 LCD
32 to 60KB Flash, 2KB RAM, SPI + I2C + UART/LIN +
IrDA, 128 LCD controller
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, DMA, 3 op amps
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Analog comparator, HW multiplier
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, A-comp, 3 op
amp, HW multiplier
5 ch. 16-bit SD ADC, 2 ch. 12-bit DAC, comparator_A,
2 op amps
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L138
New products are listed in bold red.
50
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Component Recommendations (Continued)
Component
Description
Key Features
Other TI
Solutions
Benefits
Processors (Continued)
TMS320C5000™
DSP
Power efficient, high performance
Fixed-point DSP with industry’s best combination of
standby and dynamic power consumption
TMS320C5505
Low-Power DSP
16-/8-bit EMIF, 320K bytes on-chip RAM, USB 2.0
full- and high-speed device
High-performance, low-power
TMS320F28x™
32-Bit MCU
TMS320F2802x/3x
Piccolo™
32-Bit
Microcontroller
32-bit architecture, fixed- or floating-point code, up to
225MIPS operation
Up to 60MHz C28x™ core with optional control law
accelerator. Up to 128KB Flash, high resolution (150ps)
PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
TMS320F2823x,
TMS320F2833x
TMS320F283x
Delfino,
TMS320F280x
TMS320F283x
Delfino™
32-Bit
Floating-point
Microcontroller
Up to 300MHz C28x™ core. Up to 512KB Flash, high
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN, QEP,
external memory bus, DMA.
TMS320VC5506
DSP
200MHz, dual MAC, very low stand-by power of 0.12mW
Microcontroller integration, real-time control
performance
With dedicated, high precision peripherals, Piccolo
microcontrollers are the ultimate combination of
performance, integration, size, and low cost. Ideal for
precision sensing and control applications.
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point brings
increased performance and quicker development.
Ideal for precision sensing and control applications.
Supported by eXpressDSP™ and many other software
packages and tools
TMS320VC5509A
Low-Power DSP
Up to 200MHz, dual MAC, 256KB RAM/64KB ROM,
USB 2.0 full speed, MMC/SD, 10-bit ADC
Power efficient, large on-chip memory, rich peripheral
set allows for various portable connectivity; C55x code
compatibility
C550x DSP
bq2410x
TMS320F2802x/3x
Piccolo,
TMS320F280x
TMS320VC5509A,
TMS320VC5502
Power Management
bq2406x
Battery Charger
Linear 1-cell Li-Ion charger with thermal regulation, 6.5V
OVP, temp sense
Good for space-limited designs with need for battery
safety
bq27500
Fuel Gauge
System side Impedance Track™
Accurately know remaining battery capacity, state-ofcharge, run-time to empty
TPS61081
LED Boost
Converter
Input to output isolation
Protection from short between any pins and between
any pin to ground
TPS61042
TPS61093
OLED Boost
Converter
Wide VIN range, input-output disconnect
Flexible, fail safe solution
TPS61080
TPS62230
Step-Down
Converter
Up to 90dB PSRR, excellent AC and transient load
regulation
Low noise regulation, 12mm2 solution size
TPS62260
TPS62400
Dual Output StepDown Converter
180° out of phase operation, serial interface
Flexible voltage adjustment for processors and MCUs
TPS62410
TPS63030
Buck-Boost
Converter
1A switch, automatic transition between step down and
boost mode
Extending application run time, small solution
TPS61020
TPS717xx
Single-Channel
LDO
Very high rejection of power-source noise
Low-noise power rails for sensitive analog
components
TPS795xx,
TPS799xx
TPS71710
Low-Noise SingleChannel LDO
High bandwidth, very high rejection of power source
noise
Low-noise power rails for sensitive analog
components
TPS759xx,
TPS739xx
TPS718xx-yy
Dual-Channel
LDO
Very high rejection of power-source noise
Low-noise power rails for sensitive analog
components
TPS719xx-yy
TPS780xx
LDO with DVS
Dynamic voltage scaling (DVS) with low IQ 500nA
DVS voltage designed to operate with MSP430™ to
increase power savings
TPS78101
TPS78001
Single-Channel
LDO
Dual-level, fixed output voltages, ultra-low IQ
Adjustable VOUT for optimal performance, longer
battery life
TPS78101
CC1101
Sub-1GHz RF
Transceiver
Wake-on-radio functionality; integrated packet handling
with 64B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2 to 500kbps; extremely fast PLL turn-on/hop time
Ideal for low-power systems; any low-end MCU can
be used; backwards compatible with existing systems;
suitable for fast frequency-hopping systems
CC2500
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temperature
range; AES-128 security module
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal for
industrial applications; no external processor needed
for secure communication
CC2530
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
MCU, USB 2.0, Flash and RAM in one package; four
flexible power modes for reduced power consumption;
includes CC1101 transceiver frequency synthesizer;
built-in AES-128 encryption coprocessor
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
RF ICs
RF Transceivers
RF Systems-on-Chip
CC2560
CC1110/11
2.4GHz Bluetooth®
2.1 Chipset
Sub-1GHz
System-on-Chip
CC2510, CC2511
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
51
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Component
Description
Key Features
Other TI
Solutions
Benefits
RF ICs (Continued)
RF Systems-on-Chip (Continued)
CC2530/31
Second
Generation
System-on-Chip
Solution for
2.4GHz IEEE
802.15.4/RF4CE/
ZigBee
Excellent RX sensitivity, low power, easy-to-use
development tools
RF design SOC for quick time to market; provides a
robust and complte ZigBee USB dongle or firmwareupgradable network node.
CC2530ZNP
Second
Generation
Zstack Network
Processor
ZigBee stack and radio in one chip; implements ZigBee
certified stack; configurable device type and network
settings
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery-operated, excellent selectivity and
blocking performance systems; excellent coexistence
with Bluetooth ® technology and Wi-Fi.
CC2540
2.4GHz
Bluetooth® Low
Energy compliant
RF System-on-Chip
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity, selectivity
and blocking performance
A fast-to-market Bluetooth® low energy compliant
solution
WL1271
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
Single-chip 802.11b/g/n WLAN and Bluetooth® solution
using TI’s digital radio processor technology using a
single antenna.
Single-chip 802.11a/b/g/n WLAN and Bluetooth® solution
using TI's digital radio processor technology using a
single antenna.
Sophisticated low-power technology ideal for battery operated
solutions; coexistence features enable simultaneous WLAN
and Bluetooth® operations; supports ANT+ standard.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
Second
Generation
Z-Stack™
Network Processor
ZigBee stack and radio in one chip; implements ZigBee
certified stack; configurable device type and network
settings; excellent selectivity and blocking performance
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery operated systems; excellent
coexistence with Bluetooth® technology and Wi-Fi.
Pulse Oximeter
(PO or SpO2)
Analog Front
End Module for
the C5515 PO or
SpO2 Medical
Development Kit
Display of oxygen level percentage ranging from zero to
100 percent; display of pulse rate, ranging from 20 to
300; real-time display of plethysmogram on PC; sensor
off detection; common signal conditioning path for red
and infrared signal
Based on industry’s lowest power DSP processor –
TMS320C5515
WL1273
CC2590/91,
CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Toolkits
TMDXMDKPO8328
*Page 49
New products are listed in bold red. Preview products are listed in bold blue.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
52
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Portable Respiration Device
Other TI Components to
Consider
TMS320C2000™ 32-bit controllers are
used in portable respiration applications
like portable oxygen concentrators
because the real-time control capability
allows for very precise control of the
BLDC motor, even at high speeds. This
optimizes system power consumption
and enhances the durability and relia­
bility necessary in portable respiratory
equipment.
A portable respiration device supports
a patient with the correct dose of
oxygen. One pressure sensor in front
of the valve measures the breathe-in
air and another one after the valve
measures the breathe-out pressure. A microprocessor uses the data from
the two pressure sensors and single
flow sensor to calculate the output of
the valve that is regulating the airflow. The medical staff can set the right air
flow by a touch screen or key pad. A
portable device, used in an ambulance
for example, has sophisticated power
management circuitry to support mains
and battery operation.
• F2802x/F2803x Piccolo™ series
32-bit MCUs
• DRV103 as valve driver
• Power amplifier family OPA54x,
OPA56x as valve driver
• bq power management ICs for battery charging and fuel gauge
• LED drivers
• Low-power wireless for future
designs
• RS-485 (SN65HVD3082), CAN
(SN65HVD251) or other interface ICs
for the communication between the
sensor and controller board
• Stellaris® Cortex M3 microcontrollers
Further Information
Pressure sensors play an important role for respiration equipment. See page 53 for a short tutorial on
pressure sensing techniques and
considerations.
Oxygen
Valve
Pinch
Valve
Flow
Sensors
O2
Air
Valve
Heater and
Temp Control
Mixer
Mixer
Valve
Valve
Breath
Entry
Pump
Sensor
Exhalation
Valve
Humidifier
Pump
Compressor
Air
Airway
Pressure
Sensor
Sensor
Pump
Pump
Sensor
Water Level Sensor
DAC
DAC
Valve Drive
Amplifiers
DAC
DAC
Air Flow and
Pressure
Controller
1 2
6 7
1 323445 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
1 2
6 7
1 3234 45 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
1 2
6 7
1 3234 45 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
1 2
6 7
1 323445 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
Backlight
Touch Screen
Control
Low Noise Power
ADC
Sensor
Amplifiers
System Control
Audio
ADC
Isolated AC/DC
Supply
(Green Mode)
AC Line
Clock
REF
Level Shift
Memory
Power
Back-Up
Battery
System
Power
FLASH/
EPROM
Plug
Logic
DAC
Audio Amp
SDRAM
Temp Sense
Fan Control
LCD
DAC
ADC
DAC
DAC
Operator/Patient
Feedback
and Monitors
Core and
I/O Power
PC
Interfaces
Medical
System
Interfaces
LEGEND
Power and Battery Management
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Portable respiratory device system block diagram.
Medical Applications Guide
53
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Pressure sensors convert a physical
value (weight, level, force, and flow)
into a differential signal in the mV/V
range and are referred to as metal
thick-film, ceramic or piezo-resistive. The majority of designers use the
cost-effective piezo-sensors (25mbar
to 25bar). However, these are very
non­linear, temperature dependent and
have large offset and offset drift. Plus,
they require attention to electronic
calibration and compensation.
2.7
Uncorrected
Bridge Output
2.4
Nonlinaerity (%FSR)
2.1
1.8
1.5
1.2
0.9
0.6
0.3
Corrected
Bridge Output
0
–0.3
The block diagram (below) shows the
functional block diagram of a pressure
signal conditioning system.
Sensor Signal Conditioning — performs
all necessary functions to calibrate,
compensate for temperature variance,
scale, and linearize the sensor signal.
Analog/Digital Processing — there are
two ways to convert and linearize the
sensor signal. The analog technique
results in an analog solution and provides an analog output. This technique
is inexpensive and fast, but limited to
a maximum of 11- to 16-bit resolution. Digital is more precise, up to 24-bits,
and provides a digital output at moderate speed.
The bridge excitation linearization circuit is optimized for bridge pressure
non­linearities with a parabolic shape
1
0
2
3
4
5
6
Bridge Output (mV)
7
8
9
10
PGA309 bridge pressure nonlinearity correction.
(shown above). The linearization circuit
is digitally programmable, but the pure
analog signal conditioning side is handled by the same process as in TI’s
well-known 4-20mA transmitters, such
as XTR105, XTR108 or XTR117. The
heart of the PGA309 is a precision, lowdrift programmable gain instrumentation
amplifier using an auto-zero technique
and includes a programmable fault
monitor and over/underscale limiter. It
also offers a digital temperature compensation circuit. Calibration is carried
out either via a one-wire digital serial
interface or through a two-wire industry-
standard connection.
Calibration parameters are stored in
an external nonvolatile memory to
eliminate manual trimming and achieve
long-term stability. An evaluation module, PGA309EVM (see below) includes
software and calibration sheet for easy
evaluation of your sensor + PGA309
combination.
The highly integrated, CMOS PGA309,
available in TSSOP-16, is tailored for
bridge pressure sensors and adds to
TI’s portfolio of highly flexible, lowest
noise amplifier and instrumentation
amplifier solutions that also include the
OPAx227, OPAx132, OPA335, OPA735,
INA326, INA333, INA118 and INA122.
Power
Supply
+ –
VS
VCC
RS232
Customer
Sensor
PRG
VIN
VOUT
GND
PRG
–
PGA309
+
10nF
GND
SDA
SCL
EEPROM
PC
PGA309
PC Interface Board
Temperature
Chamber
PGA309
Sensor Interface Board
–40˚C < Temperature < +125˚C
Pressure
Input
Block diagram of the PGA309EVM module.
Medical Applications Guide
54
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
32-Bit Microcontrollers
TMS320C28x™
Get samples and datasheets at: www.ti.com/c2000
• Floating-point and fixed-point
microcontrollers
• Up to 150MIPS or 300MFLOPS
• A mix of 16-bit and 32-bit
instructions
• Unified memory architecture
• Best-in-class compiler efficiency
• Single-cycle 32 x 32-bit multiply
accumulate
• Up to 512KB on-chip Flash and
68KB on-chip SRAM
• 12-bit ADC with 80ns conversion
time and 16 input channels
• Six-channel DMA
• High-resolution PWM with 150ps
accuracy
• PWM microcontrollers with programmable deadband-, phase- or dutycycle control and up to six trip zones
can create any waveform required
• SCI, SPI, I2C, McBSP and CAN ports
• Industrial (–40°C to 85°C) or
extended (–40°C to 125°C) temperature ranges. Fully automotive
qualified.
The C2000™ MCU uses a modified Harvard architecture to unify a high­performance 32-bit core with different on-chip peripherals. An advanced interrupt
management system ensures fast interrupt response. Combined with integrated
Flash and RAM memory blocks, the C2000 MCU provides a powerful single-chip
solution ideal for many embedded applications.
The C28x™ generation of microcontrollers is optimized for delivering the highestperformance control solution with the best time to market.
Flash
Boot
ROM
RAM
PWM
QEP
Memory Bus
CAP
ADC
DMA
Interrupt Management
C28x™ 32-Bit Core
32 x 32-Bit
Multiplier
Pheripheral Bus
Key Features
Atomic
ALU
GPIO
SPI
SCI
I2C
Timers
Real-Time
JTAG
EMIF
32-Bit
Floating-Point
Unit
CAN
McBSP
TMS320C28x™ 32-bit microcontroller block diagram.
Medical Applications Guide
55
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Complete Voltage-Output, Programmable Bridge Sensor Signal Conditioner
PGA309
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/PGA309
Key Features
• Ratiometric or absolute voltage
output
• Digitally calibrated via single-wire or
two-wire interface
• Eliminates potentiometer and
trimming
• Low, time-stable total adjusted error
• +2.7V to +5.5V operation
• Packaging: Small TSSOP-16
The PGA309 is a programmable analog signal conditioner designed for bridge
sensors. The analog signal path amplifies the sensor signal and provides digital
calibration for zero, span, zero drift, span drift, and sensor linearization errors with
applied stress (pressure, strain, etc.). The calibration is done via a one-wire digital
serial interface or through a two-wire industry-standard connection. The calibration
parameters are stored in external nonvolatile memory (typically SOT23-5) to eliminate manual trimming and achieve long-term stability.
VS
VEXC
Applications
• Bridge sensors
• Remote 4mA to 20mA transmitters
• Strain, load, weight scales
• Automotive sensors
0
psi
50
Non-Linear
Bridge
Transducer
Linearization
DAC
Analog Sensor Linearization
Fault
Monitor
Ref
Linearization
Circuit
Over/Under
Scale Limiter
Auto-Zero
PGA
Linear VOUT
Analog Signal Conditioning
Digital Temperature
Compensation
*See also the new PGA308
Ext
Temp
Ext Temp
DIGITAL CAL
Int
Temp
Temp
ADC
Control Register
Interface Circuitry
EEPROM
(SOT23-5)
PGA309 functional block diagram.
High-Voltage, High-Current Operational Amplifier
OPA549
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/OPA549
Key Features
• High output current: 8A continuous,
10A peak
• Wide power supply range:
• Single supply: +8V to +60V
• Dual supply: ±4V to ±30V
• Wide output voltage swing
• High slew rate: 9V/µs
• Control reference pin
• Fully protected: thermal shutdown,
adjustable current limit
• Output disable control
• Packaging: 11-pin power package
The OPA549 is a high-voltage, high current op amp designed for driving a wide
variety of loads. It provides low-level signal accuracy and high output voltage and
current. It is internally protected against overtemperature conditions and current
overloads. In addition, the OPA549 provides an accurate, user-selected current
limit. Unlike other designs which use a “power” resistor in series with the output
current path, the OPA549 senses the load indirectly. This allows the current limit to
be adjusted from 0A to 10A with
V+
a resistor/potentiometer, or controlled digitally with a voltageout or current-out DAC.
OPA549
VO
Applications
ILIM
RCL sets the current limit
• Valve, actuator drivers
Ref
value from 0A to 10A.
RCL (Very low power dissipation)
• Synchro, servo drivers
• Test equipment
E/S Pin:
E/S
• Transducer excitation
V–
• Power supplies
Forced Low: Output disabled.
Indicates Low: Thermal shutdown.
OPA549 functional block diagram.
Medical Applications Guide
56
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
High-Side Measurement, Bidirectional, Zerø-Drift Current-Shunt Monitor
INA210, INA211, INA212, INA213, INA214
Get samples and datasheets at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with INA210, INA211, INA212, INA213 or INA214)
Key Features
• Wide common-mode range: –0.3 to 26V
• Offset voltage: ±35µV (max) (enables
shunt drops of 10mV full-scale)
• Accurate:
• Gain: ±1% (max)
• Offset drift: 0.05µV/°C (max)
• Gain drift: 25ppm/°C (max)
• Choice of gain range: 50 to 1000V/V
• Supply voltage: +2.7 to +18V
• Quiescent current: 100µA (max)
• Packaging: SC70
The INA21x devices are voltage-output-current shunt monitors that can sense
drops across shunts at common-mode voltages from –0.3 to 26V, independent
of the supply voltage. Five gains are available: 50V/V, 100V/V, 200V/V, 500V/V or
1000V/V. The low offset of the zero-drift series architecture enables current sensing
with maximum drops across the shunt as low as 10mV full-scale.
Reference
Voltage
RSHUNT
3mΩ
Supply
REF
Output
OUT
R1
R3
GND
Load
IN–
Applications
• Medical equipment
• Notebook computers
• Cell phones
• Battery chargers
+2.7V to +26V
CBYPASS
0.01µF
to
0.1µF
IN+
V+
R2
R4
Product
Gain
R3 and R4
R1 and R2
INA210
INA211
INA212
INA213
INA214
200
500
1000
50
100
5kΩ
2kΩ
1kΩ
20kΩ
10kΩ
1MΩ
1MΩ
1MΩ
1MΩ
1MΩ
Typical device configuration options.
Medical Applications Guide
57
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers
DRV8402
PWM Motor Driver
24A peak current, 52.5V supplies, 500kHz PWM input
Precision motor control in a complete integrated solution
INA210/11/12/13/14
*Page 57
Current Shunt
Monitor
±35μV (max) offset, 0.05μV/°C (max) drift, 2.7 to 18V supply
voltage
Enables current sensing with maximum drops across the
shunt as low as 10mV full-scale
OPA549 *Page 56
Power Amplifier
8A continuous, 10A peak output current, 9µs slew rate
Wide supply range, thermal protection
OPA564
Power Amplifer
1.5A, 24V, 17MHz, power operational amplifier
Near rail output, current and thermal protection
OPA567
Power Amplifier
2A output, 150mV of rails with I/O = 2A output swing
Thermal protection, adj. current limit
OPA569
PGA309
*Page 56
Prog. Sensor
Conditioner
Sensor error compensation: span, offset, temp drifts
Complete bridge sensor conditioner
PGA308
THS452X
Low Power FDA
1.14mA quiescent current (typ), +2.5V to 5.5V supply,
4.6nV/√Hz voltage noise
Low power enables high accuracy, low crosstalk in
multichannel options
THS4522,
THS4524
ADS1258
Delta-Sigma ADC
16-channel, 24-bit, 125kSPS, 23.7kSPS/channel
Fastest multi-channel, delta-sigma ADC, measures all
16 inputs in <675µs
ADS1251, ADS1253,
ADS1271
Delta-Sigma ADC
24-bit, 105kSPS, serial interface, SPI w/FSYNC
Designed for multi-channel systems
ADS1278
ADS1298
Delta-Sigma ADC
ECG/EEG AFE
24-bit, 128kSPS, 8 channels, 111dB SNR
24-bit, 8 PGA, 8 ADC, plus RLD and RESP
ADS8318/19
High-Speed SAR
16-bit, 500kSPS, 18mW at 500kSPS power, ±1 LSB INL
Simultaneous measurement, onboard decimation filter
Complete front end, reduction in power and size, increase
reliability
Precision, excellent AC/DC performance
ADS1274,
ADS1278, ADS1284
ADS1271, ADS1274
ADS1294, ADS1296,
ADS1198, ADS1251/58
ADS8326
Low-Power ADC
16-bit, 250kSPS, 2.7V to 5.5V supply,
±1.5 LSB (max) INL
Small package, wide supply range
DAC7564
Quad DAC
Ultra-low glitch, voltage output DAC
Internal low drift reference
DAC7568
Octal DAC
Ultra-low glitch, voltage output DAC
Internal low drift reference
DAC8411
High Resolution DAC
16-bit, low power DAC
Small size, wide supply range
DAC8311, DAC7311
AM3517
Applications
Processor
ARM® Cortex-A8, graphics acelerators, Ethernet, CAN
High performance at handheld power levels
AM3505
MSP430F20xx
Ultra-Low-Power
16-Bit MCU
1KB/2KB Flash, 128B RAM, SPI+I2C
8 ch. 12-bit ADC or 4 ch. 16-bit SD ADC, 4 x 4mm
package
MSP430F22x4
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 512B/1KB RAM, SPI + I2C +
UART/LIN + IrDA
12 ch. 10-bit ADC, 2 op amps
MSP430F23x0
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 1KB/2KB RAM, SPI + I2C + UART/LIN
+ IrDA
Analog comparator, HW multiplier
MSP430F41x
Ultra-Low-Power
16-Bit MCU
4 to 32KB Flash, 256B to 1KB RAM, SVS,
96 segment LCD
Analog comparator
MSP430F43x
Ultra-Low-Power
16-Bit MCU
16 to 32KB Flash, 512B/1KB RAM, SPI + UART, SVS,
160 segment LCD
8 ch. 12-bit ADC, analog comparator
MSP430F44x
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 1KB/2KB RAM, 2x SPI + UART, SVS,
160 segment LCD
8 ch. 12-bit ADC, HW multiplier
MSP430F471xx
Ultra-Low-Power
16-Bit MCU
120KB Flash, 8KB RAM, (4) USCI, DMA, 160 segment
LCD
(7) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
MSP430F54xxA
Ultra-Low-Power
16-Bit MCU
128 to 256KB Flash, 16KB RAM, (4) USCI, PMM, DMA,
temp. sensor
16 ch. 12-bit ADC, analog comparator, RTC, internal
voltage regulator for power optimization
MSP430FG42x0
Ultra-Low-Power
16-Bit MCU
16 to 32KB Flash, 256B RAM, 56 segment LCD
5 ch. 16-bit SD ADC, 12-bit DAC, 2 integrated op amps
MSP430FG43x
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 1KB/2KB RAM, SPI + UART, SVS,
128 segment LCD
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, DMA, 3 op amps
MSP430FG461x
Ultra-Low-Power
16-Bit MCU
92 to 120KB Flash, 4KB/8KB RAM, SPI + I2C +
UART/LIN + IrDA, 160 LCD
12 ch. 12-bit ADC, 2 ch.12-bit DAC, A-comp,
3 op amps, HW multiplier
MSP430FG47x
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 2KB RAM, SPI + I2C + UART/LIN +
IrDA, 128 LCD controller
5 ch. 16-bit SD ADC, 2 ch. 12-bit DAC, A-comp,
2 op amps
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator,
video accelerators
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L137
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™
floating-point DSP core, rich peripheral set including
10/100 Ethernet MAC, LCD controller, USB 2.0 HS OTG,
USB 1.1 full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
OMAP-L138
Stellaris®
LM3S3xxx
Microcontroller
ARM® Cortex-M3, up to 256KB flash, up to
64kB RAM, USB host/device
USB, 10-bit ADC, temperature sensor
OPA547, OPA548
Data Converters
DAC8564
Processors
New products are listed in bold red. Preview products are listed in bold blue.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
58
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Processors (Continued)
TMS320C28x™
*Page 55
32-Bit MCU
Up to 512KB on-chip flash and
68KB on-chip SRAM, up to 150MIPS or 300MFLOPS
Optimized for delivering the highest-performance
control solution with the best time to market
TMS320C5000™
DSP
Power efficient, high performance
Fixed-point DSP with industry’s best combination of
standby and dynamic power consumption
TMS320F28x™
32-Bit MCU
TMS320F2802x/3x
Piccolo
32-Bit
Microcontroller
32-bit architecture, fixed- or floating-point code, up to
225MIPS operation
Up to 60 MHz C28x™ core with optional control law
accelerator. Up to 128KB Flash, high resolution (150ps)
PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
TMS320F2823x,
TMS320F2833x
TMS320F283x
Delfino,
TMS320F280x
TMS320F2808
32-Bit MCUs
32-bit microcontroller integration, real-time control
performance
With dedicated, high precision peripherals, Piccolo
microcontrollers are the ultimate combination of
performance, integration, size, and low cost. Ideal for
precision sensing and control applications.
I2C, 4 SPI, 2 SCI, 2 CAN
TMS320F283x
Delfino
32-Bit
Floating-point
Microcontroller
TMS320F2802x/3x
Piccolo,
TMS320F280x
TMS320F28234
32-Bit MCUs
150MIPS, 8KB ROM, 68KB RAM, 256KB Flash, 12-bit
ADC
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point brings
increased performance and quicker development.
Ideal for precision sensing and control applications.
McBSP, 1 SPI, 2 SCI, 2 CAN
TMS320F28015
32-Bit MCUs
60MIPS, 8KB ROM, 12KB RAM, 32KB Flash, 12-bit ADC
I2C, 1 SPI, 1 SCI
TMS320VC5506
DSP
200MHz, dual MAC, very low standby power of
0.12mW
Supported by eXpressDSP™ and many other software
packages and tools
TMS320VC5509A,
TMS320VC5502
SN65HVD1050
CAN Transceiver
–27V to 40V bus-fault protection, meets or exceeds
ISO11898-2
High EMI, low EME
HVD234 is 3.3V
version
SN65HVD3082
RS-485
Transceiver
1/8 unit load — up to 256 nodes on a bus, 15kV ESD
protection
Glitch-free power-up/down bus inputs and outputs
100MIPS, 8KB ROM, 36KB RAM, 128KB Flash, 12-bit
ADC
Up to 300 MHz C28x™ core. Up to 512KB Flash, high
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN, QEP,
external memory bus, DMA.
Interface
Power Management
bq2406x
Battery Charger
Linear 1-cell Li-Ion charger with thermal regulation,
6.5V OVP, temp sense
Good for space-limited designs with need for battery
safety
bq2410x
bq27010
Battery Fuel
Gauge
Li-Ion and Li-Pol battery gas gauge
Reports accurate time-to-empty of battery
bq27200
bq27540
Battery Fuel
Gauge
Li-Ion battery gas gauge with Impedance Track™
fuel-gauge technology
Reports accurate time-to-empty of battery
bq27510
TPS2041B
USB Power
Switches
USB compliant power source, short-circuit protection
Single-chip power-source solution for USB and
memory cards
TPS2550, TPS2061
TPS22902
Load Switch w/
Controller Turn-On
Low on resistance, controlled turn-on, ultra small 0.64mm2
package, quick output discharge
Ultra-small, fully integrated solution
TPS22901, TPS22922,
TPS22924C, TPS22960
TPS22946
Current Limited
Load Switch
Configurable current limit, ultra-small package, 1µA
quiescent current at 1.8 V
Ultra-small, low quiescent current current limited switch
TPS22949,
TPS22945
TPS23750
Power-overEthernet
PoE interface and DC/DC controller in one IC
Transmit power and data to remote devices over
Ethernet cable
TPS23753
TPS23753
Power-overEthernet
PoE with AC adaptor ORing function
Allows 12V adaptor ORing
TPS61042
LED Boost
Converter
Current source with over voltage protection
Simple backlight boost for improved visibility of LCD
TPS61097-33
Boost Converter
with Bypass
Switch
Highly efficient, operates down to 0.3 V; bypass switch;
5nA shutdown current; SOT-23
Super efficient boost, works over entire battery range,
low quiescent current, integrate the bypass switch, small
package
TPS61240
Boost Converter
Input current limit, load disconnect during shutdown
Small, fail save solution
TPS61070
TPS62230
Step-Down
Converter
Up to 90dB PSRR, excellent AC and transient load
regulation
Low noise regulation, 12mm2 solution size
TPS62260
TPS62400
Dual Output
Step-Down
Converter
180° out of phase operation, serial interface
Flexible voltage adjustment for processors and MCUs
TPS62410
TPS62750
Step-Down
Converter
Programmable input current limit, hot plug and reverse
current protection
Supports USB powerde applications and large output
caps
TPS62040
TPS61140
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
59
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
TPS63000
Buck Boost
Converter
Automatic transition between step down and boost
mode
Produce mid-range voltage out over entire range of
battery
TPS62113
TPS63030
Buck-Boost
Converter
1-A switch, automatic transition between step down
and boost mode
Extending application run time, small solution
TPS61020
TPS717xx
Low-Noise
Single-Channel
LDO
Very high rejection of power-source noise
Low-noise power rails for sensitive analog
components
TPS793xx,
TPS795xx,
TPS799xx
TPS718
Dual-Channel
LDO
Very high rejection of power-source noise
Low-noise power rails for sensitive analog
components
TPS719
TPS780xx
LDO with DVS
Dynamic voltage scaling (DVS) with low IQ 500nA
DVS voltage designed to operate with MSP430™ to
increase power savings
TPS78101
TPS79901
Low-Noise
Single-Channel
LDO
Very high rejection of power source noise
Low-noise power rails for sensitive analog
components
TPS793xx,
TPS795xx
CC1101
Sub-1GHz RF
Transceiver
Wake-on-radio functionality; integrated packet
handling with 64B data FIFOs; high RF flexibility: FSK,
MSK, OOK, 1.2-500kbps; extremely fast PLL turn-on/
hop time
Ideal for low-power systems; any low-end MCU can
be used; backwards compatible with existing systems;
suitable for fast frequency-hopping systems
CC2500
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4
RF Transceiver
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temperature
range; AES-128 security module
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal for
industrial applications; no external processor needed
for secure communication
CC2530
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
MCU, USB 2.0, Flash and RAM in one package; four
flexible power modes for reduced power consumption;
includes CC1101 transceiver frequency synthesizer;
built-in AES-128 encryption coprocessor
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
CC2530/31
Second
Generation
System-on-Chip
Solution for
2.4GHz IEEE
802.15.4/RF4CE/
ZigBee®
Excellent RX sensitivity, low power, easy-to-use
development tools
RF design SOC for quick time to market; provides a
robust and complete ZigBee USB dongle or firmwareupgradable network node
CC2540
2.4 GHz
Bluetooth®
Low Energy
compliant RF
System-on-Chip
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity,
selectivity and blocking performance
Fast-to-market Bluetooth® low energy compliant
solution
WL1271
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
Single-chip 802.11b/g/n WLAN and Bluetooth®
solution using TI’s digital radio processor technology
using a single antenna.
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
Sophisticated low-power technology ideal for battery operated
solutions; coexistence features enable simultaneous WLAN
and Bluetooth® operations ; supports ANT+ standard.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
ZigBee stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings; excellent selectivity and blocking
performance
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery operated systems; excellent
coexistence with Bluetooth® technology and Wi-Fi.
RF ICs
RF Transceivers
RF Systems-on-Chip
CC2560
CC2510/11
WL1273
CC2510, CC2511
CC2590/91,
CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Second
Generation
Z-Stack™
Network Processor
New products are listed in bold red. Preview products are listed in bold blue.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
60
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
Continuous positive airway pressure
(CPAP) is a method of respiratory ventilation used mainly for the treatment
of sleep apnea at home. Sleep apnea
occurs during sleep when the muscles
tend to relax naturally, causing the
upper airway to narrow. This narrowing
reduces the amount of oxygen in the
blood and causes arousal from sleep.
Pressure sensors play an important role
in respiration equipment. In addition to
converting physical values such as air-
way pressure and flow into a differen­tial
signal, air and flow sensors generate
signals that help the microprocessor
regulate the motor to adjust/maintain
the desired pressure as the person
inhales or exhales.
The sensors are very cost-effective. Large offset and offset drift cause the
signals to be off-scale, temperaturevariant and nonlinear. Amplifiers with
low offset voltage and drift over time
and temperature are ideal for signal
conditioning.
DC motor control can be accomplished
by monitoring at least two of the three
current phases, along with the DC bus
voltage feeding the motor drive bridge. For phase currents, two approaches
can be used: high-side or low-side.
Direct phase measurement, or highside, requires high-speed difference
amplifiers or current-shunt monitors
and is generally more accurate. The
low-side approach takes measurements near the half-bridge ground
connection and uses simpler amplifiers
that can be less costly but also less
precise. The DC motor is driven by
discrete FETs.
Devices in TI’s DRV family offer an
integrated driver and bridge with 12-V Bus
Pump
Humidity
Temperature
Flow Rate
Sensor Pressure
Pump
High-Side
Monitor Option
Low-Side
Monitor Option
Humidifier
Blower
REF
Water Level
Sensor
Buffer
Optional
3Ø Current
Measurement
Feedback and Monitors
Clock
REF
ADC
1 2
6 7
1 3234 45 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
1 2
6 7
1 323445 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
LCD
ADC
DAC
ADC
Backlight
ADC
Processor
Core and
I/O Power
MOSFET
Driver
Touch Screen
Control
Audio
DAC
Audio Amp
RS-232
DC Measure
ADC
Logic
AC Line
System
Power
FLASH/
EPROM
Isolated AC/DC
Supply With
Green Mode
SDRAM
Level Shift
Plug
Audio
Alerts
Hot Swap
Temp Sense
Fan Control
LEGEND
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
CPAP system block diagram.
Medical Applications Guide
61
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
thermal protection and are smaller,
more precise and much more efficient.
The microprocessor performs multiple
operations. These operations include
sampling the pressure signals and
computing a desired airway pressure
and flow level to communicate with the
motor. To achieve these operations
efficiently and in real-time, a high-speed,
low-power, highly-integrated micro­
processor should be used. A highquality DSP can be used for such
applications and will also provide the
patient ultra-quiet operation.
High-Performance 32-Bit Microcontroller for CPAP Machines
TMS320C2000™
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/c2000
Continuous Positive Airway Pressure
(CPAP) machines are an effective means
of preventing intubation, decreasing
mortality in patients with acute respiratory failure, helping patients with sleep
apnea and reducing chronic respiratory
failure.
Designers of CPAP machines are concerned with the efficiency of the motor
that drives the continuous airflow to
the patient, and try to reduce the number of components on the system
board for lower cost, easier development and quicker time to market. CPAP systems designers value the
TMS320C2000 for its exceptional
capabilities, including:
1. TMS320C2000 32-bit microcontrol­
lers are high-performance, low-cost
Flash
ICs that control motor speed, position and torque in real time. If
necessary these controllers can
even provide the processing power
for executing highly sophisticated
position and speed estimation algorithms to control the motor using
data from resolver, encoder and
hall-effect sensor.
2. These high-performance controllers
not only provide accurate control of
the motor but can also provide
additional MIPS and peripheral
integration to act as the host MCU. These ICs can perform up to 150MIPS
and have a high level of peripheral
integration with on-chip flash, a
12-bit, 16-channel ADC with up to
12.5MSPS performance and multiple
Boot
ROM
RAM
GPIO pins so designers can use a
single controller for a lower cost.
3. The C2000™ platform has a free
extensive motor control library (www.ti.com/c2000appsw) that can
help a developer get the software
framework necessary to control
either a single-phase or three-phase
BLDC motor. In addition, the
C-compiler efficiency eliminates the
need for most assembly coding.
Key Features
• Real-time control reducing overall
system cost
• Scalable controller offers from sub$2 for 150MIPS
• Software and tool compatibility
across full family
PWM
QEP
Memory Bus
Host MCU
• LCD
• I/O
CAP
Interrupt Management
C28x™ 32-Bit Core
32 x 32-Bit
Multiplier
Pheripheral Bus
ADC
DMA
Atomic
ALU
EMIF
GPIO
• Speed Control
SPI
32-Bit
Floating-Point
Unit
Patient
Monitoring
• PWM
SCI
• ADC for Back EMF
I2C
Timers
Real-Time
JTAG
• Store Patient Data
• Sometimes Sensored
Driver
+
Inverter
Compressor:
Brushless
or
DC Motor
CAN
McBSP
TMS320C2000™ 32-bit MCU in simplified patient
monitoring system.
TMS320C2000™ 32-bit MCU block diagram.
Medical Applications Guide
62
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
Key Features (Continued)
• On-chip programmable flash
• C-compiler efficiency eliminates the
need for most assembly coding
• 10- or 12-bit ADCs with up to 16
channels and 12.5MSPS
• Independent or complementary
PWM with deadband
• Independent duty-cycle or phase
control
• 150ps high-resolution PWM
• Encoder interfaces and event capture inputs
• CAN 2.0B, SCI, SPI, and I2C port
interfaces
• Long product life cycle assures supply continuity
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
AM3517
TMS320C2000™
*Page 62
TMS320F2802x/3x
Piccolo™
Applications
Processor
High-Performance
Microcontroller
32-Bit
Microcontroller
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
High performance at handheld power levels
32-bit, up to 150MIPS, up to 12.5MSPS
High-performance, low cost
Up to 60MHz C28x™ core with optional control law
accelerator. Up to 128KB Flash, high resolution (150ps)
PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
With dedicated, high precision peripherals, Piccolo
microcontrollers are the ultimate combination of
performance, integration, size, and low cost. Ideal for
precision sensing and control applications.
TMS320F283x
Delfino,
TMS320F280x
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point brings
increased performance and quicker development.
Ideal for precision sensing and control applications.
TMS320F2802x/3x
Piccolo,
TMS320F280x
AM3505
TMS320F28015
High-Speed
Microcontroller
32-bit digital signal controller with flash
TMS320F2812
High-Speed
Microcontroller
32-bit digital signal controller with flash
TMS320F28232
Digital Signal
Controller
High-performance static CMOS technology. Highly
integrated, high-performance solutions for demanding
control applications
TMS320F28234
Digital Signal
Controller
High-performance static CMOS technology. Highly
integrated, high-performance solutions for demanding
control applications
TMS320F28235
Digital Signal
Controller
TMS320F283x
Delfino
32-Bit
Floating-point
Microcontroller
High-performance static CMOS technology. Highly
integrated, high-performance solutions for demanding
control applications
Up to 300 MHz C28x™ core. Up to 512KB Flash, high
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN, QEP,
external memory bus, DMA.
TMS320F28335
Digital Signal
Controller
High-performance static CMOS technology. Highly
integrated, high-performance solutions for demanding
control applications
TMS320VC5509A
Low-Power DSP
Up to 200MHz, dual MAC, 256KB RAM/64KB ROM, USB
2.0 full speed, MMC/SD, 10-bit ADC
Power efficient; large on-chip memory, rich peripheral
set allows for various portable connectivity; C55x™
code compatibility
C550x DSP
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L137
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low
system cost and maximum flexibility for connectivity,
GUI and high-level OS options. Extends product battery
life by providing greater than 60% power reduction
over existing solutions in the market.
OMAP-L138
Stellaris®
LM3S3xxx
Microcontroller
ARM® Cortex-M3, up to 256KB flash, up to 64kB RAM,
USB host/device
USB, 10-bit ADC, temperature sensor
ADS1258
Delta-Sigma ADC
16-channel, 24-bit, 125kSPS, 23.7kSPS/channel
Fastest multi-channel, delta-sigma ADC, measures all
16 inputs in <675μs
ADS1158, ADS1248
ADS7952
SAR ADC
12-bit, 1MSPS, 70dB SNR, 11.5mW power
Zero latency, ideal for multi-channel systems
ADS7951, ADS7953
Data Converters
ADS8317
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
Excellent linearity, micropower, high speed
ADS8422
ADS8318
SAR ADC
16-bit, 500kSPS, 18mW (typ) power, 95.5dB SNR,
±1 LSB (max) INL
Zero latency, serial interface, low power
ADS8519, ADS8321
ADS8326
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
Low noise, low power, high speed
ADS8325
ADS8331/32
SAR ADC
16-bit, 500kSPS, 4/8 channels, with serial interface
ADS8342
ADS8201
Low-Power SAR
ADC
8 channel, 12-bit, 100kSPS, 1.32mW power consumption
at 100kSPS
Mux out feature can be used to reduce system part
count and overall cost
Full on-chip data acquisition system
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
ADS7870
New products are listed in bold red.
63
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Data Converters (Continued)
ADS8472
SAR ADC
16-bit, 1MSPS, ±0.4LSB (typ) INL
Zero latency, low power
TLV320DAC3120
Low-Power
Audio DAC
Mono DAC with 2.5W mono Class-D speaker amplifier;
miniDSP for audio processing
Longer battery life, better audio quality, lower cost
TLV320DAC3101
TLV320DAC32
Audio DAC
Low-power stereo DAC, 4 outputs, HP/speaker amplifier,
3D effects
TSC2000
Touch-Screen
Controller
4-wire programmable touch-screen controller with
8-/10-/12-bit 125kHz ADC and SPI interface
TSC2003
Touch-Screen
Controller
4-wire touch-screen controller
TSC2006
Touch-Screen
Controller
Nano-power touch-screen controller with SPI serial
interface
TSC2007
Touch-Screen
Controller
Nano-power touch-screen controller with I2C serial
interface
TSC2046
Touch-Screen
Controller
4-wire touch-screen controller with low-voltage
digital I/O
TSC2200
Touch-Screen
Controller
Programmable 4-wire touch-screen controller with
12-bit 125kHz ADC and keypad interface
REF3030
Series Voltage
3.0V, 50ppm/°C, 50µA in SOT23-3
Low power, small size
REF2930
REF3130
Series Voltage
20ppm/°C max, 100µA, SOT23-3
Precision, low power, small size
REF3330
CDCE913
Programmable
1-PLL VCXO
Clock Synthesizer
with 2.5 or 3.3V
LVCMOS Outputs
Input clock: X-tal (8 to 32MHz) or LVCMOS up to 150MHz;
VCXO input with ±150ppm (typ) pulling range; output
frequencies up to 230MHz; three low-jitter, low-skew,
high-performance LVCMOS output fan-out buffers
Wide input/output frequency range supports wide
frequency ratio for audio/video clocking; easy
frequency synchronization; fractional PLL enables zero
PPM clocking generation; integrated fan-out buffers
reduce clock distribution cost
CDCEL913
Programmable
1-PLL VCXO
Clock Synthesizer
with 1.8V
LVCMOS Outputs
Input clock: X-tal (8 to 32MHz) or LVCMOS up to 150MHz;
VCXO input with ±150ppm (typ) pulling range; output
frequencies up to 230MHz; three low-jitter, low-skew,
high-performance LVCMOS output fan-out buffers
Wide input/output frequency range supports wide
frequency ratio for audio/video clocking; easy
frequency synchronization; fractional PLL enables zero
PPM clocking generation; integrated fan-out buffers
reduce clock distribution cost
ISO721
Single-Channel,
100Mbps Digital
Isolator
Silicon-integrated SiO2 dielectric capacitor; 0 to 150Mbps
and DC signal pass with fail-safe; 1ns skew, 1ns jitter,
1ns pulse distortion; input threshold; noise filter; high
magnetic immunity (1E6 > inductive)
Proven reliability of SiO2 dielectric, stable over tem­
perature and moisture; lowest skew, jitter and pulse
width distortion; filters noisy signals before entering
system; high immunity for noisy environments
ISO7221C
Dual-Channel,
1/1, 25Mbps
Digital Isolator
Silicon-integrated SiO2 dielectric capacitor; 0 to 150Mbps
and DC signal pass with fail-safe; 1ns skew, 1ns jitter,
1ns pulse distortion; input threshold; noise filter; high
magnetic immunity (1E6 > inductive)
Proven reliability of SiO2 dielectric, stable over tem­
perature and moisture; lowest skew, jitter and pulse
width distortion; filters noisy signals before entering
system; high immunity for noisy environments
ISO7231C
Triple-Channel,
2/1, 25Mbps
Digital Isolator
Silicon-integrated SiO2 dielectric capacitor; 0 to 150Mbps
and DC signal pass with fail-safe; 1ns skew, 1ns jitter,
1ns pulse distortion; input threshold; noise filter; high
magnetic immunity (1E6 > inductive)
Proven reliability of SiO2 dielectric, stable over tem­
perature and moisture; lowest skew, jitter and pulse
width distortion; filters noisy signals before entering
system; high immunity for noisy environments
ISO7241M
Quad-Channel,
3/1, 150Mbps
Digital Isolator
Silicon-integrated SiO2 dielectric capacitor; 0 to 150Mbps
and DC signal pass with fail-safe; 1ns skew, 1ns jitter,
1ns pulse distortion; input threshold; noise filter; high
magnetic immunity (1E6 > inductive)
Proven reliability of SiO2 dielectric, stable over tem­
perature and moisture; lowest skew, jitter and pulse
width distortion; filters noisy signals before entering
system; high immunity for noisy environments
OPA4376
Precision Op Amp
Quad, 5.5MHz GBW, 2V/µs
— slew rate, 0.95mA/ch IQ,
76dB CMRR, 7.5nV/√Hz noise
Precision, low power
OPA4727, OPA2376
INA169
Current-Shunt
Monitor
2.7V to 60V, 60µA (typ) IQ, unipolar, high-side current
measurement
High speed, small size
INA168, INA139
INA170
Current-Shunt
Monitor
2.7V to 40V supply, 2.7V to 60V common-mode voltage,
75µA (typ) IQ, bidirectional
Low power, current output
INA193, INA138
INA210
Current-Shunt
Monitor
–0.3V to 26V common-mode range, ±35µV offset,
100µA IQ, 0.5µV/°C (max) offset drift
Voltage output, bidirectional, zero-drift series
INA138, INA193
INA332
Instrumentation
Amp
0.07%, 2ppm/°C, G = 5 gain accuracy, 73dB CMRR,
0.5pA IB, 490µA (max/ch) IQ
Single or bipolar operation, low noise
INA326, INA338
INA333
Instrumentation
Amp
25μV (max) offset, 50nV/°C drift, 50 μA (typ) Iq
Best offset/noise combination, supply down to 1.8V,
low power
INA321, INA118
References
Clocking
Interface
Amplifiers
New products are listed in bold red.
view more system block diagram compatible products, visit www.ti.com/medical
To
Medical Applications Guide
64
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers (Continued)
OPA333
OPA2365
Precision Op
Amp
Precision Op Amp
1.8V min supply, 0.017mA/ch (max), 10μV offset (max),
0.05 μV/°C drift (max)
Dual, zero crossover,
0.0006% THD+N, 100dB CMRR,
—
RRIO, 4.5nV/√Hz noise, 50MHz GBW, 200µV input offset
OPA376
Precision Op Amp
TLC2264
Op Amp
7.5nV/√Hz noise, 760µA(typ)/ch Iq, 5µV (typ) offset, input
EMI filter, RRO
—
Quad, 12nV/√Hz (typ) noise, 1pA bias current, 500µA
(max) IQ, RRO
THS452X
Low power FDA
+2.5V to 5.5V supply, 1.14mA (typ) quiescent current,
4.6nV/√Hz voltage noise
TPA2006D1
Analog-Input
Class-D Amp
1.45W mono, filter-free Class D, 1.8V shutdown
TPA2010D1
Analog-Input
Class-D Amp
TPA2013D1
Zero drift, high precision, low power, EMI input
Superior performance, excellent for driving singlesupply ADCs
OPA335, OPA378,
OPA330
OPA2333
Low noise, low power, low input bias
OPA340, OPA337
Single or split supply, low noise
TLC2274
Low power, low noise enables high accuracy
THS4522, THS4524
2.5W mono, fully differential, filter-free Class D, in WCSP
Loud audio, long battery life, small package size
TPA2031D1
Analog-Input
Class-D Amp
2.7W constant output power, mono, Class D, integrated
boost converter
Louder audio at low battery levels
TPA2014D1
TPA2016D2
Analog-Input
Class-D Amp
1.7W stereo, Class D with dynamic range compression
and automatic gain control
TPA6205A1
Class-AB Audio
Amp
1.25W mono, fully differential, Class AB, 1.8V shutdown
Loud audio, low cost
TPA6204A1
TPA6211A1
Class-AB Audio
Amp
3.1W mono, fully differential, Class AB
Loud audio
Power Management
TPS2550
USB Power
Switch
Adjustable current-limited power-distribution switch
Allows custom current set limit for different designs
TPS2811
MOSFET Driver
Inverting dual high-speed MOSFET drivers with internal
regulator
Saves solution space
TPS3103E12
Supervisory
Circuit
Ultra-low-supply-current/supply-voltage supervisory
circuit
Saves battery power
TPS3813I50
Supervisory
Circuit
Supervisor with programmable watchdog window
Allows custom time intervals
TPS40077
DC/DC Controller
Wide-input (8V to 40V), up to 1MHz-frequency
synchronous buck controller, source only
Higher frequency requires smaller inductor and input
capacitor
TPS40200
DC/DC Controller
4.5V to 52V input non-synchronous buck DC/DC
controller
Very wide input allows wider range of solutions
TPS5410
DC/DC Converter
5.5V to 36V input, 1A step-down converter
Wide input range provides for mulitple input solutions
TPS54310
DC/DC Converter
Low-input-voltage, 3A synchronous buck converter with
adjustable output voltage
Higher efficiency with synchronous solution
TPS54350
DC/DC Converter
4.5 to 20VIN, 3A DC/DC with integrated switch FET, sync
pin, enable
Eliminate beat noise/ceramic caps/FPGA/integration
TPS54550
TPS61050
White LED Driver
1.2A high-power white LED driver with I2C-compatible
interface
Provides I2C control
TPS61058
TPS61093
OLED Boost
Converter
Wide VIN range, input-output disconnect
Flexible, fail safe solution
TPS61080
TPS61140
White LED Driver
Dual, 2x 27V, 700mA switch, 1.2MHz boost converter
with single-inductor white LED and OLED driver
High switching frequency requires smaller inductor
and input capacitor
TPS61160
White LED Driver
White LED driver with digital and PWM brightness
control in 2mm x 2mm package
Will allow stepped brightness adjustment
TPS61061
TPS62110
Step-Down
Converter
3.1V to 17V VIN, 1.5-A conversion, synchronization pin, low
battery indicator, power save mode
Very low noise/high efficiency
TPS62050
TPS62230
Step-Down
Converter
Up to 90dB PSRR, excellent AC and transient load
regulation
Low noise regulation, 12mm2 solution size
TPS62260
TPS62750
Step-Down
Converter
Programmable input current limit, hot plug and reverse
current protection
Supports USB powerde applications and large output
caps
TPS62040
TPS65120
DC/DC Converter
5V/20mA (I/O), 4-ch high-accuracy multi-converter
w/3.3V LDO for LCD bias
Complete solution in one package
TPS65123
DC/DC Converter
5V/20mA (I/O), 4-ch high-accuracy multi-converter w/o
LDO for LCD bias
Complete solution in one package
New products are listed in bold red.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
65
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
TPS65124
DC/DC Converter
5V/20mA (I/O), 4-ch high-accuracy multi-converter w/o
LDO and w/programmable seq. for LCD bias
Complete solution in one package
TPS65130
DC/DC Converter
800mA boost current w/positive and negative (dual)
output for OLED and CCD sensor
Provides smaller solution size
TPS73025
LDO
Single-output LDO, 200mA, fixed (2.5V), high PSRR,
low noise
High PSRR requires less noise filtering in sensitive
applications
TPS73028
LDO
Single-output LDO, 200mA, fixed (2.8V), high PSRR,
low noise
High PSRR requires less noise filtering in sensitive
applications
TPS75103
LDO
Low-dropout, two-bank LED driver with PWM
brightness control
Will allow stepped brightness adjustment
TPS75105
LDO
Low-dropout, two-bank LED driver with PWM
brightness control
Will allow stepped brightness adjustment
TPS767D301
LDO
Dual-output LDO voltage regulator
Core and I/O voltage rails in one LDO
TPS79718
LDO
Single-output LDO, 50mA, fixed (1.8V), low quiescent
current, power-good output
Better battery life with PG signal for the processor
TPS79730
LDO
Single-output LDO, 50mA, fixed (3.0V), low quiescent
current, power-good output
Better battery life with PG signal for the processor
.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
66
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Dialysis Machine
Satisfying Safety Criteria
A dialysis machine is an artificial kidney
that treats the blood of people who
have inadequate kidney function. Dialysis machines are processor-based
and incorporate electromechanically
controlled extracorporeal blood paths
that leverage pumps and semi-­
permeable dialyzer membranes to filter
the person’s blood. From an operational perspective,
­dialysis equipment must meet specific
safety criteria. One of these criteria is
single-fault tolerance, which means no
single point-of-failure in the pumps,
motors, tubes or electronics will
endanger the patient. To achieve
µController
A safe mode of operation involves
disabling the arterial blood pump and
clamping the venous line to prevent
5V
Bus
12 V
Bus
5V
Bus
12 V
Bus
Card Power
Core I/O Power
24 V
Bus
AC Line
SVS/
Watchdog
Sensor Control Board
AC/DC
Supply
Main Power Supply
Motor/Pump Driver
EEPROM
ADC
Venous Pressure
Card
Power
Transducer
Core I/O
Power
µController
Detector
Vent Valve
Level Sense
Card Power
Core I/O
Power
Arterial Pressure
Clock
VCO
Line Clamp
Card
Power
Reference
Clock
µController
Pumps
and
Pump Motors
Clock
Card Power Reference
ADC
Pump
Buffers
Other Sensor
Control Cards
Plug
Fan
Driver
Temperature
Sensor
Buffers
Keypad
Clock
EEPROM
LED Driver
LCD Display
LCD
Backlight
Main System Board
Audio Alerts
single-point tolerance, there must be
several redundant components and
circuits, as well as “watchdog” managed-disengage system mechanisms. ADC
ADC
ADC
ADC
Transducer
Clock
ADC
Reference
Card
Power
µController
RPM
Core I/O
Power
ADC
ADC
Pump
Leak and Color Detection
LEGEND
Processor
Interface
RF/IF
Amplifier
Product Availability and Design Disclaimer – The system block
diagram depicted above and the devices recommended are
designed in this manner as a reference. Please contact your
local TI sales office or distributor for system design specifics
and product availability.
Logic
Power
ADC/DAC
Clocks
Other
Human Arm
Dialysis machine system block diagram.
Medical Applications Guide
67
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Dialysis Machine
unsafe blood from flowing to the
patient. Both active and passive components, such as control devices,
sensors, motors, heaters, pumps and
valve drivers, are needed for this type
of functionality.
the response across the entire system
instead of reacting to random stimuli. The ADCs used must provide high
reliability, good noise immunity (since
there are motors and pumps in the
system) and good precision. The typical electronic circuits in a ­dialysis
machine include the sensor control
board, arterial and venous control card,
and motor and pump drivers.
Arterial and Venous Control Card
Sensor Control Board
Sensor control boards contain analogto-digital converters (ADCs), precision
references, clocks and VCOs, as well
as instrumentation or operation amplifiers. Although these circuits need to
respond quickly, they are often geared
more toward precision than high speed
to satisfy the need to verify a measure­
ment or alarm signal and coordinate
These portions of a system may include
functions like arterial and venous
­pressure sensors, blood pumps, line
clamps, level sensors, blood detection
sensors and various monitoring and
control features. TI’s C2000™ 32-bit microcontrollers
are a great fit for motor-control and
industrial-sensor applications. These
MCUs provide drive and diagnostic
capabilities, while allowing the implementation of RPM and motor coil current sensing. They also offer the ability
to read pressure transducers and can
support required system redundancy
at a minimal cost. Motor and Pump Drivers
There are a number of motors, pumps,
valves and heaters in a dialysis
machine. Each of these may need
a specific drive circuit, while some
can be driven directly by a C2xxx
controller. Selecting the appropriate
digital-to-analog converter (DAC) and
drive amplifier is important to motor/
pump control and life expectancy. Driving any of the values or motors too
hard, with signals that are to noisy, can
cause them to run hot and degrade
quickly. This can negatively affect the
patient’s comfort while connected to
the machine. Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
AM3517
OMAP3530
Applications
Processor
Applications
Processor
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
High performance at handheld power levels
AM3505
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L138
OMAP-L137
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
Stellaris®
LM3S3xxx
Microcontroller
ARM® Cortex-M3, up to 256KB flash, up to 64kB RAM,
USB host/device
USB, 10-bit ADC, temperature sensor
TMS320F28022
Low-End 32-Bit
MCU with Analog
Integration
Small packages, integration, real-time control
performance
System cost optimization
F2802x Piccolo™
Series
TMS320F28032
Mid-End 32-Bit
MCU with Analog
Integration
Integration, up to 128KB Flash, control-law accelerator,
real-time control performance
System cost optimization, performance at lower
power
F2803x Piccolo
Series
TMS320F2808
Mid-End 32-Bit
MCU
Integration, 12 derivatives pin-to-pin compatible from
60MHz to 100Hz, real-time control performance
System cost optimization, scalability in design
F280x derivatives
series
TMS320F28234
High-End 32-Bit
Fixed-Point MCU
Integration, performances, pin-to-pin compatibility with
floating point
Room for performance and application evolution
F28232, F28235
TMS320F28334
High-End 32-Bit
Floating-Point MCU
Integration, performances, unique pin-to-pin compatibility
with fixed point, supports both fixed and floating
Ease of development, room for performance and
software evolution
F28332, F28335
Data Converters
ADS1115
Delta-Sigma ADC
16 bit, 860SPS, 4 SE, 2 Diff input, PGA, MUX, Comparator,
VREF
Smallest 16-bit ADC – 2.0 x 1.5 x .04 mm leadless
QFN pkg – reduces system size and component count
ADS1013/14/15/
ADS1113/14/
ADS1251
Delta-Sigma ADC
24-bit, 20kSPS, 7.5mW power, 1.5ppm low noise
Precision, wide dynamic range
ADS1252/53/58
ADS7866
SAR ADC, Serial
1.2V, 12-bit, 200kSPS (max), 85dB SFDR
Very small, low power
ADS7924
Micropower SAR
ADC
12-bit, 100kSPS, 4 channel, ≤1µA power down current,
I2C interface, QFN package
Intelleigent system power management and self
monitoring
ADS7951
SAR ADC
12-bit, 8-channel, 1MSPS, SPI interface w/threshold
alarms, QFN package
Low power, small package, and excellent
performance
ADS7955, ADS7959
ADS8201
Low-Power SAR
ADC
8 channel, 12-bit, 100kSPS, 1.32mW power consumption
at 100kSPS
Full on-chip data acquisition system
ADS7870
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Medical Applications Guide
New products are listed in bold red..
68
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Dialysis Machine
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Data Converters (Continued)
ADS8326
SAR ADC
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max) INL,
SE input
Low power, small package, and wide supply range
ADS8317
DAC8806
Multiplying DAC
14-bit, 0.5µs settling time, 2MSPS update rate, parallel
interface, 2.7V to 5.5V supply
Low noise, low power
DAC7742
DAC8811
Multiplying DAC
16-bit, serial input, 0.5µs settling time, 2MSPS update
rate, 0.025mW power
Low noise, low power
DAC7811, DAC8801
DAC8820
Multiplying DAC
16-bit, parallel input, 0.5µs settling time, 2MSPS update
rate, 0.025mW power, current output
Parallel interface for high-speed communications
DAC7541, DAC8806
INA118
Instrumentation Amp
110dB CMRR, 5nA (max) bias current, 50μV (max) offset
Wide BW at high gains, ±1.35V to ±18V supply
INA128
INA126
Instrumentation Amp
175µA/ch supply, 3µV/°C (max) drift, 250µV (max) offset
Precision low power, ±1.35V to ±8V supply
INA2126 (dual)
INA333
Instrumentation Amp
25μV (max) offset, 50nV/°C drift, 50μA (typ) Iq
Best offset/noise combination, supply down to 1.8V,
low power
INA321, INA326
OPA141
Precision Op Amp
10MHz, 6.5nV/√Hz, ±4.5V to ±18V, 1.8mA typical, FET input:
IB = 20pA max
—
1.1nV/√Hz noise at 1kHz, ±2.25V to ±18V supply, 80MHz BW
—
Dual, 2nV/√Hz input noise, 1.2mV input offset, 240MHz
GBWP, 90mA output, 4.8mA/ch IQ, +5V to +12V supply
1.8V (min) VS, 0.017mA (max)/ch IQ, Vos 10μA (max), Vos
drift 0.05 μV/°C (max)
Zero crossover,
0.0006% THD+N, 100dB CMRR, RRIO,
—
4.5nV/√Hz noise, 50MHz GBW, 200µV input offset
Common mode voltage range includes GND
OPA827
Unity gain stable, RRO, wide supply range
OPA227
High speed, wide input and output voltage swing,
excellent DC accuracy
Zero drift, high precision, low power, EMI input
OPA2690, OPA842
Amplifiers
OPA211
Precision Op Amp
OPA2822
High-Speed Amp
OPA333
Precision Op Amp
OPA365
Op Amp
OPA695
High-Speed Amp
1400MHz BW (G = +2), 4300V/µs slew rate, 129mW
power, ±4.2V output voltage swing
Wide bandwidth, current feedback, low power,
excellent accuracy
OPA847, OPA691
THS4521
Low Power FDA
1.14mA (typ) quiescent current, fully differential rail-torail output, negative rail input
Low power, fully differential
THS4522,
THS4524
TPA2006D1
Analog-Input
Class-D Amp
1.45W mono, filter-free Class D, 1.8V shutdown
TPA2010D1
Analog-Input
Class-D Amp
2.5W mono, fully differential, filter-free Class D, in WCSP
Loud audio, long battery life, small package size
TPA2031D1
TPA2013D1
Analog-Input
Class-D Amp
2.7W constant output power, mono, Class D, integrated
boost converter
Louder audio at low battery levels
TPA2014D1
TPA6205A1
Class-AB Audio
Amp
1.25W mono, fully differential, Class AB, 1.8V shutdown
Loud audio, low cost
TPA751
TPA6211A1
Class-AB Audio
Amp
3.1W mono, fully differential, Class AB
Loud audio
Wide VIN buck controller with selectable switching
frequency
Buck controller with 5-/12-/24-input voltage ranges
3A switcher with intregrated FETS
Allows designer to select best combination of input
voltage and switching frequency
Covers most common intermediate voltage buses
Provides controller and FETS in one package for
best solution size
Eliminate beat noise/ceramic caps/FPGA/integration
TPS54550
Allows ultra-small two- or three-cell alkaline or onecell Li-Ion operation
Simple backlight boost for improved visibility of LCD
TPS61140
Superior performance, excellent for driving singlesupply ADCs
OPA335, OPA378,
OPA330
OPA333, OPA211
Power Management
TPS40054
DC/DC Controller
TPS40077
TPS54310
DC/DC Controller
DC/DC Controller
TPS54350
DC/DC Converter
TPS61040
White LED Driver
TPS61042
LED Boost
Converter
Linear Charge
Management
Linear Charge
Management
Linear Charge
Management
Linear Charge
Management
LDO
TPS65010
TPS65020
TPS65023
TPS75003
TPS72501
4.5 to 20VIN 3A DC/DC with integrated switch FET, sync
pin, enable
28V boost converter for white-LED supply
Current source with overvoltage protection
Multi-channel 1-cell Li-Ion power management IC, USB/
AC charger, 2 DC/DCs, 2 LDOs, I2C interface
6-channel power management IC with 3 DC/DCs, 3 LDOs,
I2C interface and dynamic voltage scaling
6-channel power management IC with 3 DC/DCs, 3 LDOs,
I2C interface and DVS, optimized for DaVinci™ DSPs
Integrated triple-supply power management IC for Xilinx®
Spartan®
Single-output LDO, 1.0A, adjustable (1.22V to 5.5V), any
cap, low-input voltage, integrated SVS
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Provides complete solution in one package
Provides complete solution in one package
Provides complete DaVinci solution in one package
Provides all three rails in one package
Combines the LDO and SVS function in one small
package to save space
TPS726xx family
New products are listed in bold red.
69
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Infusion Pump
Infusion pumps are an effective pathway to deliver fluid, blood, and medication to a patient's vital organs. Since
the entire blood supply within a human
body circulates within 60 seconds,
substances introduced into the circulatory system are distributed rapidly. An infusion device typically consists
of three major components: the fluid
reservoir, a catheter system for transferring fluids into the body and a
device that combines electronics with
a mechanism to generate and regulate
flow. Regulated drug concentration
in the body is needed to achieve and
maintain a desired result, especially if
prolonged under-infusion or over-infusion takes place. While under-infusion
may not require sufficient therapy,
over-infusion can produce more serious
toxic side effects. interface, smart and real-time physio­
logical processing and wired and wireless connectivity options for patient
monitoring and data logging applications provide an additional level of
safety by quickly detecting compli­
cations and generating an alarm. The infusion of drugs requires high
flow-rate accuracy and flow uniformity. Sensors can be used to count the
­number of drops passing through the
drip chamber. Sensors can also provide
flow feedback for automatic rate
adjustment and detect downstream
occlusions below the pumping mechanism. However, flow-rate accuracy
remains limited by the rate and viscosity of the drip as well as improper angulation if in motion. Flow uniformity can
also suffer at low flow rates from the
discrete nature of the drop detector. One alternative to the drop sensor is a
volumetric metering chamber. A pump
with a stepper or servo-controlled DC
motor can be used to provide the driving force for the fluid by mechanized
displacement of the contents in the
volumetric chamber. The stepping
resolution, along with chamber elasticity, can influence flow uniformity. When
the volume is not uniform over the
mechanism’s cycle, software control
can be used to compensate for the
variation. Despite these limitations, a processor
with an advanced graphical user
Clock
Backlight
Keypad
Logic
REF
Touch Screen
Control
ADC
Pump
DAC
Sensor
Temp
Sense
Pump
Pump
Audio Alarms
or Instructions
Audio Amp
Processor
Pump
Driver
Wireless
Wired
ADC
Sensor
Common Interfaces
Isolated AC/DC
Supply
(Green Mode)
AC Line
Battery
Charger
Battery
Protection
Fuel
Gauge
System
Power
Memory
Power
FLASH/
EPROM
Plug
Level Shift
SDRAM
Core and
I/O Power
Low Noise Power
Interface
Protection
LEGEND
Processor
Interface
RF/IF
Amplifier
Battery
Power and Battery Management
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Infusion pump system block diagram.
Medical Applications Guide
70
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Infusion Pump
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
Applications
Processor
Ultra-Low-Power
16-Bit MCU
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
High performance at handheld power levels
32 to 60KB Flash, 1KB/2KB RAM, 8-channel 12-bit ADC,
comparator, 2x SPI + UART, SVS, 160-segment LCD
controller
Ultra-low-power, integrated analog peripherals,
hardware communication channels
MSP430FG461x
Ultra-Low-Power
16-Bit MCU
92 to 120KB Flash, 4KB/8KB RAM, 12-channel 12-bit
ADC, dual 12-bit DAC, comparator, 3 op amps,
3-channel DMA, SPI + UART, USCI, SVS, 160-segment
LCD controller
Ultra-low-power signal-chain-on-chip (SCoC),
configurable op amps, multiple hardware
communication channels
MSP430FG43x
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator,
video accelerators
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L137
Low-Power
Application
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low
OMAP-L138
system cost and maximum flexibility for connectivity,
GUI, and high-level OS options. Extends product
battery life by providing greater than 60% power
reduction over existing solutions in the market.
Stellaris®
LM3S3xxx
Microcontroller
ARM® Cortex-M3, up to 256KB flash, up to 64kB RAM,
USB host/device
USB, 10-bit ADC, temperature sensor
TMS320F28022
Low-End 32-Bit
MCU with Analog
Integration
Small packages, integration, real-time control
performance
System cost optimization
F2802x Piccolo™
series
TMS320F28032
Mid-End 32-Bit
MCU with Analog
Integration
Integration, up to 128KB Flash, control-law accelerator,
real-time control performance
System cost optimization, performance at lower
power
F2803x Piccolo series
ADS1246
Delta-Sigma ADC
24-bit, 2kHz with PGA, 50/60Hz noise rejection
Integration with performance and low power
ADS1247, ADS1248,
ADS1258
Delta-Sigma ADC
16-channel, 24-bit, 125kSPS, 23.7kSPS/channel
Fastest multi-channel, delta-sigma ADC, measures
all 16 inputs in <675μs
ADS1256, ADS1255,
ADS8344, ADS1158
ADS7952
SAR ADC
12-bit, 1MSPS, 70dB SNR, 11.5mW power
Zero latency, ideal for multi-channel systems
ADS7951, ADS7953
ADS8317
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
Excellent linearity, micropower, high speed
ADS8422
ADS8318
High-Speed SAR
16-bit, 500kSPS, 18mW at 500kSPS power, ±1 LSB INL
Precision, excellent AC/DC performance
ADS8326
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
Low noise, low power, high speed
ADS8325
ADS8331/32
SAR ADC
16-bit, 500kSPS, 4/8 channels, with serial interface
Mux out feature can be used to reduce system part
count and overall cost
ADS8342
ADS8472
SAR ADC
16-bit, 1MSPS, ±0.4LSB (typ) INL
Zero latency, low power
TLV320DAC3120
Low-Power Audio
DAC
Mono DAC with 2.5W mono Class-D speaker amplifier;
miniDSP for audio processing
Longer battery life, better audio quality, lower cost
TLV320DAC3101
TLV320DAC32
Audio DAC
Low-power stereo DAC, 4 outputs, HP/speaker amplifier,
3D effects
OPA211
Precision Op Amp
—
1.1nV/√Hz noise at 1kHz, ±2.25V to ±18V supply,
80MHz BW
Unity gain stable, RRO, wide supply range
OPA227
OPA365
Op Amp
Zero crossover,
0.0006% THD+N, 100dB CMRR, RRIO,
—
4.5nV/√Hz noise, 50MHz GBW, 200µV input offset
Superior performance, excellent for driving singlesupply ADCs
OPA333, OPA211
OPA376
Precision Op Amp
7.5nV/√Hz noise, 760μA(typ)/ch Iq, 5µV (typ) offset, input
EMI filter, RRO
Low noise, low power, low input bias
OPA340, OPA337
OPA378
Op Amp
0.4µVPP low noise, 125µA (typ) quiescent current,
0.15µV offset voltage, 2.2V to 5V supply
microPower, rail-to-rail I/O, excellent PSRR
OPA330, OPA333,
OPA335
OPA827
Precision JFET
Op Amp
4nV/√Hz noise at 1kHz, ±4V to ±18V supply, 15pA (typ)
input bias current, 22MHz BW
High precision, low noise, low input bias, wide
supply range
OPA177, OPA627,
OPA132, OPA141
INA118
Instrumentation
Amp
110dB CMRR, 5nA (max) bias current, 50µV (max) offset
Wide BW at high gains, ±1.35V to ±18V supply
INA128, INA822
INA333
Instrumentation
Amp
20µV (max) offset, 50nV/°C drift, 200pA input bias
Low power, low drift, tiny package
INA326
TPA2006D1
Analog-Input
Class-D Amp
1.45W mono, filter-free Class D, 1.8V shutdown
AM3517
MSP430F44x
AM3505
Data Converters
Amplifiers
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
.
71
New products are listed in bold red.
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Infusion Pump
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers (Continued)
TPA2010D1
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Class-AB Audio
Amp
Class-AB Audio
Amp
Low power FDA
2.5W mono, fully differential, filter-free Class D, in WCSP
Loud audio, long battery life, small package size
TPA2031D1
2.7W constant output power, mono, Class D, integrated
boost converter
1.7W stereo, Class D with dynamic range compression
and automatic gain control
1.25W mono, fully differential, Class AB, 1.8V shutdown
Louder audio at low battery levels
TPA2014D1
Loud audio, low cost
TPA6204A1
3.1W mono, fully differential, Class AB
Loud audio
1.14mA (typ) quiescent current, low distortion,
4.6nV/√Hz voltage noise
Low power, high accuracy
THS4522, THS4524
CC1101
Sub-1GHz RF
Transceiver
Wake-on-radio functionality; integrated packet handling
with 64B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2-500kbps; extremely fast PLL turn-on/hop time
CC2500
CC1150
Sub-1GHz
Transmitter
Programmable data rate from 1.2 to 500 kBaud; fast
startup time (0.3µs); low current consumption
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temperature
range; AES-128 security module
Ideal for low-power systems; any low-end MCU
can be used; backwards compatible with existing
systems; suitable for fast frequency hopping
systems
Fast development time and low system cost;
flexible optimization of range vs. power; small
solution size
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal
for industrial applications; no external processor
needed for secure communication
TPA2013D1
TPA2016D2
TPA6205A1
TPA6211A1
THS4521
RF ICs
RF Transceivers
CC2520
RF Systems-on-Chip
CC2560
CC1110/11
CC2431
CC2530/31
CC2540
WL1271
WL1273
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
MCU, USB 2.0, Flash and RAM in one package; four
flexible power modes for reduced power consumption;
includes CC1101 transceiver frequency synthesizer;
built-in AES-128 encryption coprocessor
System-on-Chip
Solution for ZigBee
location engine
Second Gen
System-on-Chip
Solution for 2.4GHz
IEEE 802.15.4/
RF4CE/ZigBee
2.4GHz
Bluetooth® Low
Energy compliant
RF System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
CC2431 has 32/64/128 KB hardware AES encryption
engine, excellent selectivity, blocking performance and
hardware location
Excellent RX sensitivity, low power, easy-to-use
development tools
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
Ideal for battery operated systems; suitable for
proprietary and ZigBee systems; adds location
awareness and accuracy of 3 to 5 meters
RF design SOC for quick time to market; provides
a robust and complete ZigBee USB dongle or
firmware-upgradable network node
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity, selectivity
and blocking performance
A fast-to-market Bluetooth® low energy compliant
solution
Single-chip 802.11b/g/n WLAN and Bluetooth® solution
using TI’s digital radio processor technology using a
single antenna.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations; supports
ANT+ standard.
Sophisticated low-power technology ideal for
battery operated solutions; coexistence features
enable simultaneous WLAN and Bluetooth®
operations; supports ANT+ standard.
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
CC2510, CC2511
CC2590/91,
CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Second
Generation
Z-Stack™
Network Processor
ZigBee® stack and radio in one chip; implements ZigBee
certified stack; configurable device type and network
settings
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery-operated excellent selectivity
and blocking performance systems; excellent
coexistence with Bluetooth® technology and Wi-Fi.
Multi-chemistry charger
One charge for both Li-Ion and NiCad/NiMH cells
High-discharge-rate battery monitor
Provides true discharge rate for high-current
battery pack
Accurately measures available cell charge
Power Management
bq2000
bq2016
bq20z80A-V110
Battery
Management
Battery
Management
Battery
Management
Patented Impedance Track™ ICs
New products are listed in bold red. Preview products are listed in bold blue.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
72
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Infusion Pump
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
TPS40054/5
DC/DC Controller
Wide VIN controller with adjustable switching frequency
TPS40057
DC/DC Controller
Wide VIN controller with adjustable switching frequency
TPS40077
TPS51020
TPS51116
TPS5124
TPS54110
DC/DC Controller
DC/DC Controller
DC/DC Controller
DC/DC Controller
DC/DC Converter
TPS54310
DC/DC Converter
TPS54350
DC/DC Converter
TPS62040
DC/DC Converter
TPS62220
DC/DC Converter
4.5 to 28V input
Synchrounous dual buck controller
Complete DDR/DDR2 solution
Synchrounous dual buck controller
Externally compensated — adjustable 1.5A integrated
FET switcher
Externally compensated — adjustable 3A integrated FET
switcher
4.5 to 20V input, 3A DC/DC with integrated switch FET,
sync pin, enable
Adjustable 1.2A, 95%-efficient step-down converter,
18µA, MSOP-10
300mA step-down converter in a SOT-23 package
TPS62300/1/2/3/5
Step-Down
Converter
DC/DC Converter
TPS62350
TPS65010
TPS65020
TPS65023
Linear Charge
Management
Linear Charge
Management
Linear Charge
Management
TPS71701
LDO
TPS73101
LDO
TPS74201
LDO
TPS76725
LDO
TPS76733
LDO
TPS76750
LDO
TPS79912
TPS79925
LDO
LDO
Allows flexibility for the input and the switching
frequency
Allows flexibility for the input and the switching
frequency
Supports 5-/12-/24-V intermediate bus voltages
Provides two outputs 180° apart in one package
Provides all output and active termination for DDR
Provides two outputs 180° apart in one package
Provides flexibility and ease of design
TPS40057
TPS40054/5
TPS5124
TPS51020
Provides flexibility and ease of design
Eliminate beat noise/ceramic caps/FPGA/
integration
Maximizes battery life with high efficiency and
low IQ
Small solution size with high-side FET
TPS54550
500mA, 3MHz synchronous step-down converter
Very small inductor and high efficiency
TPS62040
Step-down DC/DC converter with I2C interface for
dynamic voltage scaling
Fully intregrated power and battery management IC
Provides ability to increase conversion efficiency
6-channel power management IC with 3 DC/DCs,
3 LDOs, I2C interface and dynamic voltage scaling
6-channel power management IC with 3 DC/DCs,
3 LDOs, I2C interface and DVS, optimized for
DaVinci™ DSPs
Low-noise, high-bandwidth-PSRR, low-dropout 150mA
linear regulator
Single-output LDO, 150mA, adjustable (1.2V to 5.5V),
cap free, low noise, fast transient response
Single-output LDO, 1.5A, adjustable (0.8V to 3.3V), any
or no cap, programmable soft start
1A single-output LDO with low IQ and fast transient
response
1A LDO with fastest transient response plus ultra-low
supply current
1A LDO with fastest transient response plus ultra-low
supply current
High-performance 200mA in chip-scale package
High-performance 200mA in chip-scale package
Provides complete solution in one package
Provides complete solution in one package
Provides complete DaVinci solution in one package
Filters out wider range of incoming noise with the
high PSRR
Responds to transients faster to keep output
voltage in regulation
Adjust the voltage ramp rate for your processor
requirements
Efficient design allows quick response to dynamic
current requirements
Ultra-low 85µA supply current and 230mV dropout
voltage stretch battery life
Ultra-low 85µA supply current and 230mV dropout
voltage stretch battery life
Very small solution size
Very small solution size
TPS718xx family
TPS725xx family
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
73
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Automated External Defibrillator (AED)
The automated external defibrillator
(AED) is a highly sophisticated microprocessor-based device that monitors,
assesses and automatically treats
patients with life-threatening heart
rhythms. It captures ECG signals from
the therapy electrodes, runs an ECGanalysis algorithm to identify shockable
rhythms, and then advises the operator
about whether defibrillation is necessary. A basic defibrillator contains a
high-voltage power supply, storage
capacitor, optional inductor, and
patient electrodes (see block diagram). It develops an electrical charge in the
capacitor to a certain voltage, creating
the potential for current flow. The
higher the voltage, the more current
can poten­tially flow. The AED outputs
audio instructions and visual prompts
to guide the operator through the
defib­ril­lation procedure. In a typical
defibrillation sequence, the AED provides voice prompts to instruct the
user to attach the patient electrodes
and starts acquiring ECG data. If the
AED analyzes the patient’s ECG and
detects a shockable rhythm, the capac­
itor is charged according to energy
stored in the capacitor, Wc = 1/2CV2c ;
and capacitor voltage, Vc(t) = Vc(0)e–t/RC,
where R = R(lead) << R(chest).
Then, following the instructions, the
operator presses the shock button to
deliver the high-voltage pulse; so
current begins flowing through the body
to depolarize most of the heart cells,
which often re-establishes coordinated
contractions and normal rhythm. The
amount of flowing current is determined
by the capacitor and body impedance. The accompanying graph shows the
level of current and the length of time
the current flows through the body.
Many jurisdictions and medical directors
also require that the AED record the
audio from the scene of a cardiac
arrest for post-event analysis. All AEDs
include a means to store and retrieve
patient ECG patterns.
The front-end signals of the AED come
from the ECG electrodes placed on the
patient, which requires an instrumentation amplifier to amplify its very small
amplitude (<10mV). The instrumentation amplifiers INA118/INA128/INA333
are designed to have:
• Capability to sense low-amplitude
signals from 0.1mV to 10mV,
• Very high input impedance (>5MΩ),
• Very low input leakage current (<1µA),
• Flat frequency response of 0.1Hz to
100Hz and
• High common-mode rejection ratio
(CMRR) (>100dB).
The other front-end signal of the AED
is the microphone input for recording
the audio from the scene of a cardiac
arrest. Both ECG and microphone
input are digitized and processed by
a DSP. Most AED designs use a 16-bit
processor and therefore work well with
16-bit ADCs to digitize ECG and voice
input. The amplified ECG signal has
Isolated Power
Patient Monitoring Signal Chain
Patient
Monitoring
Sensor Pads
FLASH
ADC
DE-FIB
Plates
Audio
Amp
CODEC
Memory
Card
Power
Instrumentation
Buffer
Amplifier
Amplifier
High Voltage
Storage and
Discharge
Circuit
DRAM
Removable
Memory
High Voltage
Digital
Power
Controller
Speaker
Touch
Screen
Operations and Patient
Diagnostics
Backlight
System Monitoring and
Management (Wake DSP)
Display
Operator/Patient Feedback and Instructions
Low Noise
Sensor Power
Processor
Power
Battery
Charger
Keypad
Low Power Wireless
Lithium
Battery
Protection
System
Power
Fuel
Gauge
Power Supply
Battery Pack
LEGEND
Patient Monitoring and Data Upload
AC/DC Supply
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Plug
AC
Adapter
AC Line
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
AED system block diagram.
Medical Applications Guide
74
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Automated External Defibrillator (AED)
40
200J Monophasic
30
200J Biphasic
130J Biphasic
20
Current (A)
a bandwidth of 0.1Hz to 100Hz and
requires a minimum SNR of 50dB. The audio recording/playback signal
typically has a bandwidth of 8kHz and
requires a minimum SNR of 65dB. The
microphone input also needs to be
amplified with a maximum programmable gain of 40dB. The AED can have
synthesized audio instruction with
volume control output to either the
headphone speaker or the 8Ω speaker. System designers will find that the
TLV320AIC20K makes the AED frontend digitization very easy and simple
because it integrates two ADCs, two
DACs, a microphone amplifier, a headphone driver and an 8Ω driver with volume control; and it can be seamlessly interfaced to a DSP.
10
0
–10
–20
0
5
10
Time (ms)
20
15
Typical AED drive current. AEDs can deliver either monophasic or biphasic defibrillation waveforms to the heart. Monophasic delivers a current that travels in one
direction throughout the shock. Newer biphasic technology allows the current to
be reversed partway through the shock thus potentially lessening the risk of burns
and myocardial damage.
Single-Supply, microPower, RRO, CMOS Instrumentation Amplifier
INA321
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/INA321
Key Features
• Low quiescent current: 40µA/ch
• High gain accuracy: 2ppm/°C,
0.02%, G = 5
• Low offset voltage: ±200µV
• High CMRR: 94dB
• Low bias current: 10pA
• Bandwidth: 500kHz, G = 5V/V
• Gain set with external resistors
• Packaging: MSOP-8 (single);
TSSOP-14 (dual)
The INA321 is a rail-to-rail output, CMOS instrumentation amp that provides
amplification of differential signals with microPower current consumption of 40µA. It features <1µA current consumption in standby mode and returns to normal operation in microseconds making it a good choice for low-power battery or
multiplexing applications. Configured internally for 5V/V gain, the INA321 offers
exceptional flexibility with user-programmable external gain resistors. It reduces
common-mode error over frequency and with CMRR remaining high up to 3kHz,
line noise and line harmonics are rejected.
R1
160kΩ
40kΩ
R2
RG
40kΩ
160kΩ
REF
Applications
• Physiological amplifier: ECG, EEG,
EMG
• Test equipment
• Differential line receivers with gain
• Industrial sensor amplifier: bridge,
RTD, thermistor, position
A1
VIN–
VOUT
A3
A2
VIN+
Gain = 5 + 5(R2/R1)
VOUT = (VIN+ – VIN-) • Gain
Shutdown
V+
V–
INA321 functional block diagram.
Medical Applications Guide
75
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Automated External Defibrillator (AED)
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers
INA118
INA128
INA321
*Page 75
INA333
OPA333
OPA369
TPA2005D1
TPA2010D1
TPA2013D1
TPA3007D1
TPA6205A1
TPA6211A1
THS452x
Instrumentation
Amp
Instrumentation
Amp
CMOS
Instrumentation Amp
Instrumentation
Amp
Precision Op Amp
Zero-Crossover Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Class-AB
Audio Amp
Class-AB
Audio Amp
Low power FDA
110dB CMRR, 5nA (max) bias current, 50µV (max)
offset
50µV offset voltage, drift (0.5µV/°C) and high
common-mode rejection (120dB at G ≥ 100)
0.02% accuracy, 2ppm/°C drift for gain=5; 10pA
input bias current
25μV (max) offset, 50nV/°C drift, 50μA (typ) Iq
1.8V min supply, 0.017mA/ch (max), 10μV offset
(max), 0.05 μV/°C drift (max)
1.8V, 700nA, RRIO, 114dB CMMR, 0.4µV/°C drift
1.4W mono, fully differential, filter-free Class D
Wide BW at high gains, ±1.35V to ±18V supply
INA128
Wide BW at high gains
INA129
High gain accuracy
INA2321 (dual)
Best offset/noise combination, supply down to 1.8V,
low power
Zero drift, high precision, low power, EMI input
INA321, INA326
Low power, unmatched DC precision
Loud audio, long battery life
OPA335, OPA378,
OPA330
OPA379, OPA2369 (dual)
TPA2006D1
2.5W mono, fully differential, filter-free Class D, in
WCSP
2.7W constant output power, mono, Class D,
integrated boost converter
Mono, medium power, filter-free Class D
Loud audio, long battery life, small package size
TPA2031D1
Louder audio at low battery levels
TPA2014D1
1.25W mono, fully differential, Class AB, 1.8V
shutdown
3.1W mono, fully differential, Class AB
Loud audio, low cost
TPA6204A1
1.14mA (typ) quiescent current,+2.5V to 5.5V supply
Low power, single and dula supply, low distortion
THS4522, THS4524
16-bit, 860SPS, 4 SE, 2 diff input, PGA, MUX,
comparator, VREF
24-bit, 8 PGA, 8 ADC, plus RLD and RESP
Smallest 16-bit ADC, 2.0 x 1.5 x .04 mm leadless
WFN pkg; reduces system size and componenent count
Complete front end, reduction in power and size,
increase reliability
ADS1113/4,
ADS1013/14/15
ADS1294, ADS1296,
ADS1198, ADS1251/58
ADS7924, ADS8201
ADS8326
Loud audio
Data Converters
ADS1115
Delta-Sigma ADC
ADS1298
ECG/EEG AFE
ADS7866
ADS8317
SAR ADC, Serial
SAR ADC
ADS8326
Low-Power ADC
ADS8331/32
SAR ADC
MSC1210
TLV320AIC12K
Data Acq. System
Audio Codec
TLV320AIC20K
Audio Codec
TLV320AIC3104
Audio Codec
TLV320DAC3120
Low-Power Audio
DAC
Audio Converter
TLV320DAC32
TSC2003
TSC2046
Touch-Screen
Controller
Touch-Screen
Controller
1.2V, 12-bit, 200kSPS (max), 85dB SFDR
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB
(max) INL, differential input
16-bit, 250kSPS, 2.7V to 5.5V supply,
±1.5 LSB (max) INL
16-bit, 500kSPS, 4/8 channels, with serial interface
Enhanced 8051 core w/Flash memory and 24-bit ADC
Low-power, mono, voice-band codec with 8Ω
speaker amp
Low-power, stereo, voice-band codec with 8Ω
speaker amp
Low-power stereo codec, 6 inputs, 6 outputs,
headphone amp, enhanced digital effects
Mono DAC with 2.5W mono Class-D speaker
amplifier; miniDSP for audio processing
Low-power stereo DAC, 4 outputs, HP/speaker
amplifier, 3D effects
I2C interface for standard, fast, high-speed modes
Low voltage I/O, touch-pressure measurement, 2.2V
to 5.2V operation
Low power, small package, and wide supply range
Small package, wide supply range
Mux out feature can be used to reduce system part
count and overall cost
ADS8342
Fully compatible with TMS320C54x™ DSP power
supplies
TLV320AIC24K
Longer battery life, better audio quality, lower cost
TLV320DAC3101
Direct battery measurement
ADS7845, TSC2000,
TSC2007
QSPI™ and SP™ 3-wire interface
References
REF30xx
REF31xx
REF32xx
REF33xx
REF50xx
Low-Power,
Low-Drift Series
Reference
Series Voltage
Ultra-Low-Drift
Series Reference
Very-Low-Power
Series Reference
High-Precision,
Very-Low-Drift
Series Reference
50µA, 0.2% initial accuracy, 50ppm/°C max drift,
±25mA output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V,
4.096V
0.2% (max) initial accuracy, 15ppm/°C (max) drift, 100µA
1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
100µA, 0.2% initial accuracy, 7ppm/°C max drift,
±10mA output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
5µA, 0.15% initial accuracy, 30ppm/°C max drift,
±5mA output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V, 3.3V
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 2.048V, 2.5V, 3.0V, 4.096V, 4.5V, 5.0V
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
REF31xx, REF33xx,
REF29xx
Low power consumption for portable applications
REF3120, REF3125,
REF3133
Improves system accuracy
Preserves battery life, fits into physically constrained
systems
Improves system accuracy
REF30xx, REF31xx,
REF29xx
REF02
New products are listed in bold red. Preview products are listed in bold blue.
76
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Automated External Defibrillator (AED)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
Applications
Processor
Ultra-Low-Power
16-Bit MCU
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
High performance at handheld power levels
1KB/2KB Flash, 128B RAM, SPI+I2C
8 ch. 12-bit ADC or 4 ch. 16-bit SD ADC, 4 x 4mm
package
MSP430F22x4
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 512B/1KB RAM, SPI + I2C +
UART/LIN + IrDA
12 ch. 10-bit ADC, 2 op amps
MSP430F23x0
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 1KB/2KB RAM, SPI + I2C +
UART/LIN + IrDA
Analog comparator, HW multiplier
MSP430F41x
Ultra-Low-Power
16-Bit MCU
4 to 32KB Flash, 256B to 1KB RAM, SVS,
96 segment LCD
Analog comparator
MSP430F42x
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 256B to 1KB RAM, SPI + UART, SVS,
128 segment LCD
3 x 16-bit SD ADC
MSP430F42x0
Ultra-Low-Power
16-Bit MCU
16 to 32KB Flash, 256B RAM, 56 segment LCD
5 ch. 16-bit SD ADC, 12-bit DAC
MSP430F43x
Ultra-Low-Power
16-Bit MCU
16 to 32KB Flash, 512B/1KB RAM, SPI + UART, SVS,
160 segment LCD
8 ch. 12-bit ADC, analog comparator
MSP430F44x
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 1KB/2KB RAM, 2x SPI + UART,
SVS, 160 segment LCD
8 ch. 12-bit ADC, HW multiplier
MSP430F47xx
Ultra-Low-Power
16-Bit MCU
60KB Flash, 256B RAM, (4) USCI, 160 segment LCD
(4) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
MSP430F241x
Ultra-Low-Power
16-Bit MCU
120KB Flash, 8KB RAM, (4) USCI, SVS, temp. sensor
8 ch. 12-bit ADC, analog comparator, HW multiplier
MSP430F261x
Ultra-Low-Power
16-Bit MCU
120KB Flash, 8KB RAM, (4) USCI, SVS, DMA, temp.
sensor
Analog comparator, 2 ch. 12-bit DAC, 8 ch. 12-bit
ADC, HW multiplier
MSP430F471xx
Ultra-Low-Power
16-Bit MCU
120KB Flash, 8KB RAM, (4) USCI, DMA, 160
segment LCD
(7) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
MSP430F54xxA
Ultra-Low-Power
16-Bit MCU
128 to 256KB Flash, 16KB RAM, (4) USCI, PMM,
DMA, temp. sensor
16 ch. 12-bit ADC, analog comparator, RTC, internal
voltage regulator for power optimization
MSP430FG42x0
Ultra-Low-Power
16-Bit MCU
16 to 32KB Flash, 256B RAM, 56 segment LCD
5 ch. 16-bit SD ADC, 12-bit DAC, 2 integrated
op amps
MSP430FG43x
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 1KB/2KB RAM, SPI + UART, SVS,
128 segment LCD
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, DMA, 3 op amps
MSP430FG461x
Ultra-Low-Power
16-Bit MCU
92 to 120KB Flash, 4KB/8KB RAM, SPI + I2C + UART/
LIN + IrDA, 160 LCD
12 ch.12-bit ADC, 2 ch.12-bit DAC, A-comp,
3 op amps, HW multiplier
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator,
video accelerators
Laptop-like performance at handheld power levels
OMAP3503, OMAP3515,
OMAP3525
OMAP-L137
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™
floating-point DSP core, rich peripheral set including
10/100 Ethernet MAC, LCD controller, USB 2.0 HS
OTG, USB 1.1 full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
OMAP-L138
Stellaris®
LM3S3xxx
Microcontroller
ARM® Cortex-M3, up to 256KB flash, up to 64kB
RAM, USB host/device
USB, 10-bit ADC, temperature sensor
TMS320C5000™
DSP
Power efficient, high performance
Fixed-point DSP with industry’s best combination of
standby and dynamic power consumption
TMS320VC5506
DSP
200MHz, dual MAC, very low standby power of
0.12mW
Supported by eXpressDSP™ and many other
software packages and tools
TMS320VC5509A,
TMS320VC5502
bq77PL900
AM3517
MSP430F20xx
AM3505
Power Management
bq20z90-V110
Battery Fuel
Gauge
Instant accuracy better than 1% error over lifetime
of the battery
Automatically adjusts for battery aging, battery self
discharge and temperature inefficiencies
bq24100
Battery Charge
Management
Battery Charge
Management
Battery Safety
Switch mode, 1100kHz switching frequency, >2A
charge current
Multi-chemistry and multi-cell sync switch-mode
charger
Battery pack full-protection analog front end
d/dt, min current primary charge termination method
Isolated DC/DC
Converter
USB Power Switch
2W, unregulated, up to 89% efficiency, 106W/in3
power density
USB-compliant power source, short-circuit
protection
bq24721C
bq29330
DCP020515D
TPS2041B
Provides individual cell voltages and battery voltage
to battery management host
EN55022 Class B EMC performance, UL1950
component
Single-chip power source solution for USB and
memory cards
DCP02 series
TPS2550, TPS2061
New products are listed in bold red.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
High efficiency, pack and system protection functions
77
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Automated External Defibrillator (AED)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
TPS22902
TPS2550
Load Switch with
Controller Turn-On
Current Limited
Load Switch
USB Power Switch
Low on resistance, controlled turn-on, ultra small
64mm2 package, quick output discharge
Configurable current limit, ultra-small package, 1µA
quiescent current at 1.8V
Precision OC USB power switch with UL approval
TPS2828
MOSFET Driver
TPS3836
Voltage Supervisor
TPS61042
White LED Driver
TPS717xx
TPS718xx-yy
Low-Noise SingleChannel LDO
Dual-Channel LDO
2A output, 14ns rise and fall time, 24ns prop delay,
inverting
220nA supervisor with 10ms/200ms selectable
delay time
30V, 500mA switch boost converter, 1MHz switching
frequency
Very high rejection of power-source noise
TPS780xx
LDO with DVS
Dynamic voltage scaling (DVS) with low IQ 500nA
UCC38C4x
PWM Controller
UCD7100
Digital Control
Driver
14.9/9V on/off UVLO thresholds, 1MHz frequency,
50% duty cycle
Adjustable current limit, 3.3V, 10mA internal
regulator
TPS22946
Very high rejection of power-source noise
Ultra-small, fully integrated solution
Ultra-small, low quiescent current current limited switch
Provides precise adjustable current limit for multiple
applications
Drives FETs for high-voltage transformer
Circuit initialization and timing supervision
Higher switching frequency requires smaller size
inductor and capacitor
Low-noise power rails for sensitive analog
components
Low-noise power rails for sensitive analog
components
DVS voltage designed to operate with MSP430 to
increase power savings
TPS22901, TPS22922,
TPS22924C, TPS22960
TPS22949, TPS22945
TPS2551
TPS2829 non-inverting
version
TPS3809
TPS61140
TPS793xx, TPS795xx,
TPS799xx
TPS719xx-yy
TPS78101
UCC3804, UCC3809
Applications requiring fast local peak current limit
protection
RF ICs
RF Transceivers
CC1101
Sub-1GHz RF
Transceiver
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Wake-on-radio functionality; integrated packet
handling with 64B data FIFOs; high RF flexibility:
FSK, MSK, OOK, 1.2-500kbps; extremely fast PLL
turn-on/hop time
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended
temperature range; AES-128 security module
Ideal for low-power systems; any low-end MCU
can be used; backwards compatible with existing
systems; suitable for fast frequency-hopping systems
CC2500
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal for
industrial applications; no external processor needed
for secure communication
CC2530
RF Systems-on-Chip
CC2560
CC1110/11
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital
radio processor technology.
MCU, USB 2.0, Flash and RAM in one package;
four flexible power modes for reduced power
consumption; includes CC1101 transceiver
frequency synthesizer; built-in AES-128 encryption
coprocessor
CC2431 has 32/64/128 KB hardware AES encryption
engine, excellent selectivity, blocking performance
and hardware location
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
Ideal for battery operated systems;suitable for
proprietary and ZigBee systems; adds location
awareness and accuracy of 3 to 5 meters
CC2431
System-on-Chip
Solution for Zigbee
location engine
CC2530/31
Second Generation
System-on-Chip
Solution for 2.4GHz
IEEE 802.15.4/
RF4CE/ZigBee
2.4GHz Bluetooth®
Low Energy
compliant RF
System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
Excellent RX sensitivity, low power, easy-to-use
development tools
RF design SOC for quick time to market; provides a
robust and complete ZigBee USB dongle or firmwareupgradable network node
Excellent link budget enabling long range
applications without external frontend, receiver
sensitivity, selectivity and blocking performance
A fast-to-market Bluetooth® low energy compliant
solution
Single-chip 802.11b/g/n WLAN and Bluetooth®
solution using TI’s digital radio processor technology
using a single antenna.
2.4/5GHz
802.11a/b/g/n and
Bluetooth® 2.1
Chipset
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations; supports
ANT+ standard.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
CC2540
WL1271
WL1273
CC2510, CC2511
CC2590/91, CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Second Generation
Z-Stack™
Network Processor
ZigBee® stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings
New products are listed in bold red. Preview products are listed in bold blue.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery-operated excellent selectivity and
blocking performance systems; excellent coexistence
with Bluetooth® technology and Wi-Fi.
78
Texas Instruments 2010
Medical Imaging
➔ Overview
Medical imaging technology is continually evolving and advancing, all with
the goal of improving patient care. TI’s
complete analog signal chain, power
management, interface and embedded
processing portfolios empower innovation in medical imaging by:
• Enabling faster, more accurate diagnostic results.
• Increasing the speed of delivery and
availability of medical care worldwide.
• Improving accessibility and
affordability of end equipments.
There are two prevalent trends in
semiconductor innovation for the
medical imaging market:
• Increased performance driven by the
need for higher image quality.
• Decreased power consumption and
size to allow equipment designs that
are more portable, accessible and
affordable. TI’s large portfolio of catalog and
application-specific semiconductor
products addresses major medical imaging modalities such as ultrasound,
computed tomography (CT), magnetic
resonance imaging (MRI), positron
emission tomography (PET) and digital
X-ray, as well as newer innovative
modalities such as hyperspectral
imaging, optical coherence tomography (OCT), or not even yet envisioned
imaging solutions.
Power continues to be a key concern
for all of these modalities, as well as
for medical applications overall, so we
have dedicated a chapter to it towards
the end of this section. For more information on TI’s offering for Medical Imaging, please visit
www.ti.com/medicalimaging
➔ Ultrasound
Ultrasound systems
As ultrasound equipment becomes
more compact and portable, it heralds
a variety of health care applications
that illustrate how advances in medical
technology are bringing care to
patients instead of requiring them to
travel. TI’s embedded processors and
analog products facilitate advanced
ultrasound system designs with
low power consumption and high
performance, yielding portability with
high-quality images.
Medical and industrial ultrasound
systems use focal imaging techniques
to achieve imaging performance far
beyond a single-channel approach. By
using an array of receivers, TI’s latest
products for ultrasound enable high
definition images through time shifting,
scaling and intelligently summing
echo energy. This makes it possible
to focus on a single point in the scan
region; by subsequently focusing on
other points, an image is assembled.
Medical Applications Guide
When initiating a scan, a pulse is generated and transmitted from each of the eight to 512 transducer
elements. These pulses are timed
and scaled to illuminate a specific
region of the body. After transmitting,
the transducer element immediately
switches into receive mode. The pulse,
now in the form of mechanical energy,
propagates through the body as highfrequency sound waves, typically in the
range of 1 to 15MHz. As it does, the signal weakens rapidly, falling off as
the square of the distance traveled. As the signal travels, portions of the
wavefront energy are reflected back to the transducer/receiver. Limits on the amount of energy that
can be put into the body require that
the industry develop extremely sensitive receive electronics. At focal
points close to the surface, the receive
echoes are strong, requiring little if any
amplification. This region is referred to
as the near field. At focal points deep
79
in the body, the receive echoes will be
extremely weak and must be amplified by a factor of 1,000 or more. This
region is referred to as the far field. These regions represent the two extremes in which the receive electronics must operate.
In the high-gain (far field) mode, the
performance limit is the sum of all
noise sources in the receive chain. The two largest contributors of receive
noise are the transducer/cable assembly
and the receive low-noise amplifier
(LNA). In the low-gain mode (near
field), the performance limit is defined
by the magnitude of the input signal. The ratio between these two signals
defines the system’s dynamic range. Many receive chains integrate the LNA
with a voltage-controlled attenuator
(VCA) and a programmable gain amplifier (PGA).
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Integrated HV Pulser
OR
Standard Signal Chain
High Voltage Linear Amplifier
Front End
Passive
LPF
HV MUX/
DEMUX
T/R
Switches
Signal Chain
Power
Amplifier Stage
LNA
VCA
PGA
Transmit
Beamformer
DAC
Temp
Sense
Beamformer
Control Unit
Receive
Beamformer
REF
Core and I/O
Power
Amplifier + Filter
A
Analog Front
End
d
Low Pass
Filter
ADC
Mid
Preprocessing
Clocking
Transducer
Back End
Time Gain
Control
CW (analog)
Beamformer
Spectral
Doppler
Processing
AC Line
AC/DC Supply
With Green Mode
Controller
System
Power
Main Po
Power
ower Supply
ow
y
Supply Voltage
Supervisor
Color/Power
Doppler
Processing
Scan Conversion
Post Processing
ADC
Power
Plug
B Mode
Processing
DAC
Ultrasound OS/UI
LPW
RS232
USB
1394
802.11
Display
MMC/SDIO
Common Interfaces
IDE/ATA
Audio
Amp
Audio Output
LEGEND
Backlight
Touchscreen
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Ultrasound system block diagram.
Low-pass filtering is typically used
between the VCA/PGA and ADC as an anti-aliasing filter and to limit the
noise bandwidth. Depending on the
specific system, two- to five-pole filter
linear phase topologies can be found
there. In selecting an op amp, the
primary considerations include signal
swing, minimum and maximum input
frequencies, harmonic distortion, and
gain requirements.
Analog-to-digital converters (ADCs)
are typically 10- and 12-bit. SNR and
power consumption are the most
important issues, followed by channel
integration. Another trend in ADCs is
the implementation of an LVDS interface
between the ADC and the beamformer. By serializing the data coming out
of the ADC, the number of interface
lines can be reduced. This reduction
enables high system integration densities, which translates to smaller
and lower cost PC boards — an essential part of portable imaging systems.
Medical Applications Guide
The front end of the digital part of the
system takes in data from a number
of ADCs, commonly referred to as the
channel count. This number can vary
from eight for ultra-portable systems to 512 for high-end devices. For 3-D
and 4-D systems, this number can be even higher. The main function
of the digital front end is to perform
focusing at a given depth and direction. This beamforming is performed by resampling the ADC output at a
higher rate, properly delaying the resampled data, multiplying by a
weight (apodization factor), and then
summing all the weighted and delayed
outputs. Both the I/O and computational requirements for this process are extremely high. Traditionally, FPGAs and custom ASICs
have been used for digital beamforming, but today DSPs provide the ability
to handle much of the required computational load. DSPs are also well suited
80
to handle the real-time aspects of the
beamforming controller, which may
vary the delay and apodization profile
required for beamforming based on the
depth and direction of the beam.
The beamformed data is then passed
through a mid-processing block where
various filtering is performed to reduce
noise and properly extract the ultrasound RF data. This is followed by
demodulation to create complex baseband data. Adaptive processing based
on the depth and angle of measurements is sometimes used to
get an optimized ultrasound image.
The output from the mid-processing
stage is handled in the back-end in
various ways. For B-mode imaging, the
data envelope is compressed to bring
it to the dynamic range of the human
eye. Additional image enhancement,
noise reduction and speckle reduction
algorithms are performed. The data is
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
then scan converted to the final output
display form and size. For Doppler
processing, velocity and turbulence
are estimated in the color flow mode,
and power is estimated in the power
Doppler mode. These estimates are
again scan converted to the final output display form and size.
An assignment of color to the estimates is also necessary for proper
display. In spectral Doppler mode,
a windowed and overlapped FFT is
taken to estimate the spectrum. It is
also customary to present the Doppler
data, after separation of forward and
reverse flow, in the form of audio. All of these intensive signal processing
computations are well suited for DSPs.
Product portfolio for ultrasound
Analog application-specific signal
chain products
• The main function of a digital front
end in an ultrasound system is to
focus at a given depth and direction. The AFE58xx family of fully integrated
analog front ends offers parts 50
percent smaller than competitive solutions, with low power and low noise for
superior image quality. • The main function of T/R switches
is to prevent high-voltage pulses from
damaging the receive electronics.The
TX810, an eight-channel integrated
T/R switch, is designed to address designers’ need to build smaller portable ultrasound systems while speeding time to market.
• The transmit beamformer, highvoltage (HV) pulser and HV multiplexer form the transmit path
responsible for the pulse-excitation of
transducer elements. The TX734 is an
integrated, quad-channel, ±90-V pulser
with active damping that reduces noise
and minimizes size. Integrated 8- and 16-Channel Analog Front Ends
AFE5801, AFE5851
Embedded processors
• TMS320C6474 and TMS320C6455
high-performance DSPs are suitable for
ultrasound processing such as B-mode
imaging, color Doppler, speckle reduction, 3-D/4-D and other processing and
filtering algorithms. • OMAP35x SOCs are well suited to
handle the operating system, connectivity and user interface require-ments
in portable and hand-held ultrasound
systems, while also being capable of
handling processing algorithms like
color scan conversion.
These products, along with TI’s power
management products, clocks and
interfaces, provide a full signal chain
portfolio of targeted integrated circuit
solutions for ultrasound.
View the “Flexible Design, Low Power
for Ultrasound Systems” video at:
www.ti.com/ultrasoundvideo
TI’s AFE5851 analog front end was named
a best product in the 2009 Design News
Golden Mousetrap awards.
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/AFE5801 or www.ti.com/sc/device/AFE5851
Key Features
• Integrated VCA, PGA, LPF, 12-bit
65-MSPS ADC
•AFE5801:
• 8 channels
• 50mW per channel at 30MSPS
58mW per channel at 50MSPS
•AFE5851:
• 16 channels
• 39mW per channel at 32.5MSPS
•Digital gain control removes external
DAC for smaller footprint and minimized noise
• Packaging: 9 x 9mm QFN
Applications
• Ultrasound
Medical Applications Guide
The AFE5851 is the first 16-channel AFE available for the ultrasound market. The device features 39mW/channel at 32.5MSPS and contains 16 variable-gain
amplifiers (VGAs), followed by eight 12-bit, 65MSPS analog-to-digital converters
(ADCs). Each ADC is shared between two VGAs and each VGA differential output
is sampled at alternate clock cycles to optimize power dissipation. The ADC has
scalable power consumption to enhance the lower power with lower sampling
rates. The high channel count and low-power features of the AFE5851 allow for
increased channel density in handheld ultrasound systems.
Both the AFE5851 and AFE5801 can be preceded by an off-chip low-noise amplifier (LNA), which can be on the probe or be a transformer. This new architecture
enables customers
SPI
Logic/Controls
to have more than 40 percent less
LVDS
OUT
IN1
power and a Clamp
16
CH1
and
VCA/PCA
ADC
Channels
70 percent smaller
LPF
IN16
analog front-end
CH16
footprint for handReference
held ultrasound
systems.
AFE5851 functional diagram.
81
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Fully Integrated 8-Channel Analog Front Ends
AFE5804, AFE5805
TI’s AFE5805 analog front end won
Electronic Product Design’s e-Legacy
award.
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/AFE5804 or www.ti.com/sc/device/AFE5805
View the “AFE5805 8-Channel Analog Front-End for Ultrasound” video at: www.ti.com/afe5805video
Key Features
• Integrated LNA, VCA, PGA, LPF,
12-bit 50MSPS ADC
• AFE5805
• 122mW per channel at 40MSPS
—–
• 0.85nV/√Hz at 2MHz
• 250mVpp linear input range
• AFE5804
• 101mW per channel at 40MSPS
—–
• 1.23nV/√Hz at 2MHz
• 280mVpp linear input range
• LNA fixed gain: 20dB
• VCA gain can vary over a 46dB range
with a 0 to 1.2V control voltage
•PGA programmable for gains of 20dB, 25dB, 27dB and 30dB
•Packaging: 135-pin 15 x 9mm BGA
The AFE5804 and AFE5805 are integrated analog front-end solutions designed
specifically for mid-range to portable ultrasound systems. The AFE5804 features
mode control for power/noise optimization. It has the low-power performance at
101mW per channel while maintaining superior image quality. With a superior low—–
noise ­feature of 0.85nV/√Hz at 2MHz, the AFE5805 achieves performance suitable
not only for portable equipment but also for high-channel-density, mid-range ultrasound systems. The AFE5804 and AFE5805 consist of eight channels, including a low-noise amplifier (LNA), voltage-control attenuator (VCA), programmable-gain amplifier
(PGA), low-pass filter (LPF) and 12-bit, 50MSPS analog-to-digital converter (ADC)
with LVDS data ­outputs. The LVDS outputs of the ADC reduce the number of interface lines to an ASIC or FPGA, thereby enabling the high system integration densities
desired for portable systems.
Logic/Controls
SPI
Applications
• Ultrasound
8
Channels
IN1
LNA
VCA/PCA
IN8
Clamp
and
LPF
ADC
LVDS
OUT
CH1
CH8
CW Switch Matrix
IOUT(10)
Reference
(15 x 9 mm chip size)
AFE5805 ultrasound analog front end.
Medical Applications Guide
82
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
AWARDS
Integrated, 8-Channel T/R Switch
TX810
TI’s TX810 was selected as a 2010
Design News Golden Mousetrap Best
Product Finalist.
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/TX810
View the “First Integrated Ultrasound T/R Switch” video at: www.ti.com/tx810video
Key Features
• Integrates a protection diode bridge
and clamp diodes for each of its
eight channels
• Programmable bias currents
• 3-bit interface used to program a 7mA range of bias currents
• Power-down mode to reduce power consumption
• Optimized insertion loss maintains
integrity of input/output signal at 400Ω
load with 0.9dB at 7mA bias current
and 1.3dB at 1mA bias current
The TX810 addresses designers’ need to build smaller portable ultrasound systems,
while speeding time to market. The TX810 integrates a protection diode bridge and
clamp diodes for each of its eight channels to prevent the high-voltage pulses of
the transmitter from damaging the receive electronics of the ultrasound system. The
device saves more than 50 to 75 percent board space over discrete solutions in
portable to mid-range ultrasound systems, depending on T/R architectures, and the
component reduction and easier handling brings higher reliability to designs.
VP
1 Channel
of TX810
VP
HV TX
LV RX
Applications
1 Channel
of TX810
• Ultrasound
HV TX
VN
LV RX
TI’s TX734 was elected as a finalist
for Electronic Product Design’s 2009
e-Legacy awards for advancing the
future of medical
imaging.
VN
±100V, 2A, Quad-Channel Pulser
TX734
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/TX734
HV P
HV P
View the “TX734 Product Overview” video at: www.ti.com/tx734video
Key Features
• Quad channel
• Voltage: ±100V
• Peak output current: ±2A
• Active damping
• True 3-level RTZ
• Internally activated
• Imaging output frequency: Up to
20MHz
• Logic inputs: 2.5V to 5V
• Low HD2 distortion: -40dBc, at
5MHz
Applications
• Ultrasound
VDCW VECW VD VE
3-Level
Logic that require
Out1the needs of high-density
IN1P
The TX734 addresses
systems
a three-level,
FET-Output
Level
CH1
Translator
IN1
high-voltage pulse pattern by integrating four channels
of
level
translators,
drivers,
N
& Driver
Active Damping
high-voltage output stage and active damping into a 64-pin, 9mm x 9mm QFN package.
HV P HV P VDCW VECW VD VE
Out2
3-Level
FET-Output
CH2
Active damping, also called fast
Out1
Active Damping
clamping to ground, allows for a
clean three-level return-to-zero
3-Level
(RTZ) waveform. This
improves
Out3
FET-Output
CH3
pulse symmetry and delivers low
Out2
Active Damping
second order distortion of -40dB. The active damping feature in the
3-Level
TX734 prevents noise
from being FET-Output
Out4
CH4
injected into the transducer, which
Out3
improves signal sensitivity by at Active Damping
least 5dBc, resulting in better
AGND
image quality.
Out4
Logic
IN2P
Level
3-Level IN2
Translator
N
FET-Output
& Driver
CH1
Active Damping
Logic
IN3P
Level
3-Level IN3
Translator
N
FET-Output
& Driver
CH2
Active Damping
Logic
Level
Translator
3-Level
& Driver
DGND
Active Damping
3-Level
FET-Output
CH4
Active Damping
Medical Applications Guide
83
Logic
Level
Translator
& Driver
IN1P
IN1N
IN2P
IN2N
IN4P
IN4N
FET-Output
CH3
AGND
Logic
Level
Translator
& Driver
Logic
Level
Translator
& Driver
Logic
Level
Translator
& Driver
IN3P
IN3N
IN4P
IN4N
DGND
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
8-Channel, Ultra-Low-Power, 12- and 10-Bit, 50 to 65MSPS
Analog-to-Digital Converters with Serialized LVDS Interface
ADS5281, ADS5282, ADS5287
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with ADS5281, ADS5282 or ADS5287)
LVDD
(1.8V)
AVDD
(3.3V )
The ADS5281 family also incorporates advanced features to optimize system performance, including programmable gain from 0 to 12dB in 1dB steps, 1/f
(flicker) noise suppression and 6dB input overload recovery within one clock cycle. Available with 12-bit resolution at 50 and 65MSPS and 10-bit resolution at 65MSPS, the ADS5281 family has the flexibility to offer an optimal solution for
the entire spectrum of imaging systems.
(AVSS)
CLK N
• 8-channel 12- or 10-bit ADCs in one
small 64-pin QFN package
• ADS5281 also available in 80-pin
TQFP pin-compatible to ADS527x
• 77mW per channel at 65MSPS
• 64mW per channel at 50MSPS
• 70dB SNR for 12-bits at 10MHz IF
• 1/f (flicker) noise suppression
• Up to 6dB overload recovery in one
clock cycle
• Individual channel power down
• Direct interface with VCA8500
8-channel variable-gain amplifier
• Xilinx-supported deserializer code
The ADS5281 family provides eight high-performance ADCs in a small 64-pin QFN
package, making it possible to implement high channel counts in high-performance
ultrasound and other medical imaging systems. The low power dissipation per
­channel aids in making compact ultrasound equipment where space and battery life
are at a premium, and in conjunction with the VCA8500, offers a high-performance
LNA-to-digital solution for less than 130mW per channel in ultrasound applications. (ADCLK)
CLK P
Key Features
Applications
• Medical and other imaging:
• Ultrasound
• MRI
• PET
Clock
Buffer
PLL
6x ADCLK
LCLK P
12x ADCLK
LCLK N
1x ADCLK
ADCLK P
ADCLK N
IN1P
12-Bit
ADC
IN1N
Digital
OUT1P
Serializer
OUT1N
Channels
2 to 7
12-Bit
ADC
IN8N
Digital
Output
Format
Drive
Current
SCLK
Registers
SDATA
CS
RESET
REFT
REFB
VCM
ISET
INT/EXT
OUT8 N
Test
Patterns
Digital
Gain
(0 dB to
12 dB)
Reference
OUT8 P
Serializer
PowerDown
ADC
Control
PD
IN8P
ADS5281/2/7 functional diagram.
Medical Applications Guide
84
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
8-Channel Variable-Gain Amplifier with Low-Noise Amplifier
VCA8500
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/VCA8500
Key Features
• Ultra-low power: 65mW/channel
—–
• Low noise: 0.8nV/√Hz
• Low-noise amplifier (LNA):
• 20dB fixed gain
• 250mVPP linear input range
• Variable-gain amplifier:
• Gain control range: 46dB
• Selectable PGA gain:
20/25/27/30dB
• Fast overload recovery
• Output clamping control
The VCA8500 is an eight-channel variable-gain amplifier consisting of a low-noise amplifier (LNA) and a variable-gain amplifier (VGA). This combination, along with
the device features, makes it ideal for a variety of ultrasound systems.
The ultra-low-power spec of 65mW/channel is optimized for portable ultrasound
systems requiring low power consumption and for mid-range systems increasing
their number of channels per system while maintaining stringent low-power
requirements.
—–
The low-noise spec of 0.8nV/√Hz, the LNA fixed gain at 20dB and VGA gain
control range at 46dB provide excellent noise- and ­signal-handling characteristics
for improving image quality in ultrasound systems.
Applications
• Medical imaging:
• Ultrasound
• Sonar
SDI
Logic
CW Switch Matrix
(8 In x 10 Out)
LNA
IN
LNA
20dB
Attenuation
(46dB)
PGA
(20/25/
27/30
dB)
CW
OUT
Clamping
Circuit
LPF
(2-Pole)
OUT
OUT
VCA8500
(1 of 8 Channels)
Gain
Control
Functional diagram.
Medical Applications Guide
85
Texas Instruments 2010
Medical Imaging
➔ Ultrsound
Ultra-Wideband, Current-Feedback Op Amp with Disable
OPA695
Get samples, datasheets, tools and application reports at: www.ti.com/sc/device/OPA695
Key Features
• Gain = +2 bandwidth (1400MHz)
• Gain = +8 bandwidth (450MHz)
• Output voltage swing: ±4.2V
• Ultra-high slew rate: 4300V/µs
• Low power: 129mW
• Low disabled power: 0.5mW
• Packaging: SOT23-6, SO-8
The OPA695 is a single-channel, very broadband, current feedback operational
amplifier. As a gain of +2V/V line driver, it offers 1.4GHz bandwidth with 2900V/µs
slew rate. These give a 0.8ns rise time for a 2V output step — more than adequate for the highest speed video requirements. Single supply operation
extends from +5V to +12V to span the most popular supplies used for fixed gain IF amplifiers. The OPA695’s low 12.9mA supply current is precisely trimmed
at +25°C. This trim, along with a low temperature drift, gives low system power
over temperature.
+5V
Applications
• Very wideband ADC driver
• Low-cost precision IF amplifier
• Broadband video line driver
VIN
75Ω
75Ω
OPA695
511Ω
511Ω
VLOAD
RG-59
75Ω
–5V
1.2
125-MHz Input
Voltage at
Matched Load
Input/Load Voltage (V)
1
0.8
0.6
0.4
0.2
0
–0.2
Time (1ns/div)
Video line driver with a gain of +2V/V and typical pulse-response waveforms.
Medical Applications Guide
86
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Dual, Wideband, Current-Feedback Op Amp with Disable
OPA2695
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/OPA2695
Key Features
• Gain = +2V/V bandwidth (850MHz)
or +8V/V bandwidth (450MHz)
• Slew rate: 2900V/µs
• Output voltage swing: ±4.1V
• Low quiescent current: 12.9mA/
channel
• Low disable current: 200µA/channel
• Single (OPA695) and triple
(OPA3695)
• Packaging: SO-8 (without disable),
QFN-16 (with disable)
The OPA2695 is a wide-bandwidth, current-feedback amplifier with disable that
—–
features an exceptional 2900V/µs slew rate and low 1.8nV/√Hz input voltage noise. The device has been optimized for high gain operation. The pinout provides symmetrical input
+5V
and output paths, making
the OPA2695 well suited as
1/2
a differential ADC driver. The
OPA2695
low 12.9mA/channel supply
Z I = RT 2RG
RF
current is precisely trimmed
RG
500Ω
1:1
at +25°C. This trim, along
VI
with a low temperature drift,
RL
gives low system power
RT
VO
RF
800Ω
RG
over temperature.
500Ω
Applications
VO 500Ω
=
= GD
VI
RG
• Very wideband ADC drivers
• Portable instruments
• Active filters
• Low-cost precision IF amplifiers
1/2
OPA2695
–5V
Differential driver.
Dual, Low-Power, Wideband, Voltage-Feedback Op Amp with Disable
OPA2889
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/OPA2889
Key Features
• Flexible supply range:
• +2.6V to +12V single supply
• ±1.3V to ±6V dual supply
• Slew rate: 250V/µs
• Output voltage swing: ±4V
• Wideband ±5V operation: 60MHz (G = +2V/V)
• Low quiescent current: 460µA per
channel
• Low disable current: 18µA
• Packaging: SO-8, MSOP-10
Applications
The OPA2889 is a dual, wideband, low-power amplifier with disable. The new
internal architecture offers slew rate and full-power bandwidth previously found
only in wideband current-feedback amplifiers. These capabilities, coupled with a
very low quiescent current of only 460µA per channel, make it very well-suited for
portable instrumentation. Operating from a ±5V supply, the OPA2889 can deliver
a ±4V output swing
with over 40mA drive
+6V
+5V
50Ω
1kΩ
Vi
current and 60MHz
+
16Ω
1/2
0V to 4V
bandwidth, making it
ADS8472
200Ω
OPA2889
500pF
ideal as an RGB line
–
driver, single-supply
–6V
analog-to-digital (ADC)
200Ω
16-Bit
750Ω
input driver or low0.01µF
1-MSPS
power twisted-pair line
SAR ADC
750Ω
receiver.
+6V
• High-speed imaging channels
• ADC buffer
• Portable instruments
• Active filters
–
375Ω
VREF /2
1/2
OPA2889
+
–6V
16Ω
500-Hz LP
Pole
Low-power, DC-coupled, single-to-differential driver
for ≤100-kHz inputs.
Medical Applications Guide
87
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
TMS320DM6446 Digital Media Processors Featuring DaVinci™ Technology
TMS320DM6446
Get samples, datasheets, tools and application reports at: www.ti.com/davinci
Key Features
• High-performance digital media SoC
• 594MHz C64x+™ clock rate
• 297MHz ARM926EJ-S clock rate
• Eight 32-bit C64x+ instructions/
cycle
• 4752 C64x+ MIPS
• Fully software compatible with
C64x+/ARM9
• Load-store architecture with nonaligned support
• Sixty-four 32-bit general-purpose
registers
• Instruction packing reduces code size
• Video processing subsystem
• CCD and CMOS imager interface
• Preview engine for real-time image
processing
• Glueless interface to common
video decoders
• Embedded trace buffer (ETB11) with
4KB memory for ARM9 debugging
TMS320DM6446 digital media processors are ideal for ultrasound and various
other medical imaging products. TMS320DM6446 digital media processors are highly integrated SoCs based on an ARM926EJ-S processor and the
TMS320C64x+™ DSP core. They leverage TI’s DaVinci™ technology to meet the networked media encode and decode application processing needs of next-generation embedded ICs. The TMS320DM6446/41 enable developers to
quickly bring to market devices featuring robust operating systems support, rich
user interfaces, high processing performance and long battery life through the
maximum flexibility of a fully integrated mixed-processor solution.
TMS320DM6446
Video
Imaging
Coprocessor
ARM
Subsystem
DSP
Subsystem
ARM
926EJ-S
300MHz
CPU
C64x+™
DSP
600-MHz
Core
Video Processing Subsystem
Front End
Preview
CCD Controller
Video Interface
Histogram/3A
Resizer
Back End
On-Screen Video
Display
Enc
(OCD)
(VENC)
10b DAC
10b DAC
10b DAC
10b DAC
Switched Central Resource (SCR)
Applications
• Medical imaging
• Digital media
• Networked media encode/decode
Peripherals
Connectivity
USB
2.0
PHY
EDMA
Serial Interfaces
Audio
Serial
Port
I2C
SPI
UART
x3
System
EMAC
with
MDIO
VLYNQ
Timer
x2
WD PWM
Timer x3
Program/Data Storage
DDR2
Controller
(16b/32b)
Async EMF/
NANO/
SmartMedia
ATA/
Compact
Flash
MMC/
SD
TMS320DM6446 block diagram.
Medical Applications Guide
88
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Six-core TMS320C6472 Ideal for High-Performance Stringent Power Budget Applications
TMS320C6472
Get samples and datasheets at: www.ti.com/sc/device/TMS320C6472
Key Features
• Integrates six on-chip TMS320C64x+ DSP cores on a single chip
• 500/625/700MHz speed versions
• Eight 32-bit instructions/cycle
• 4000MIPS/MMACS (16-bits) at 500MHz
• Shared memory architecture
768K-byte
• Local L2 RAM per C64x+ 608K-byte
• Dedicated SPLOOP Instruction
• Switch fabric DMA engine
• Serial/deserializer (SERDES)
interfaces
• DDR2 memory interface: 533Mhz
• 10/100/1G ethernet
• High Performance Interface (HPI)
• 24 x 24mm FC-BGA package
Applications
• Ultrasound
• Medical imaging
• High performance systems
• Projects with high performance/
stringent power budgets
The TMS320C6472 multi-core digital signal processor (DSP) saves cost, power,
and board space by integrating six industry-leading cores running at up to 700Mhz
each on a single die. The C6472 delivers up to 4.2Ghz of raw DSP performance
that consumes only 60 percent of the power and occupies 80 percent less board
space than six individual TMS320C6415 DSP’s. At 3.7 watts per device, it offers
even greater power savings than compared to general purpose processors in the
same performance range. A common key requirement of many high performance
applications is the availability of large on-chip memories to handle vast amounts
of data during processing. With 768K-Byte of shared RAM and 608K-Byte local L2
RAM per C64x+ Mega-module, the TMS320C6472 device can eliminate the need
for external memory, thereby reducing system power dissipation and system cost
and optimizing board density.
C64x + Core
C64x + Core
C64x + Core
C64x + Core
C64x + Core
C64x + Core
L1
Data
L1
Data
L1
Data
L1
Data
L1
Data
L1
Data
L1
Prog
L1
Prog
L1
Prog
L1
Prog
L1
Prog
L1
Prog
L2
memory
L2
memory
L2
memory
L2
memory
L2
memory
L2
memory
Shared L2 memory
PLL
I 2C
Timers
Others
Boot ROM
HPI
Utopia II
TSIP
DDR2
EMIF
sRIO
High-density
memory system
“Switch fabric”
DMA engine
Communications
subsystem
DDR2 memory
interface
EDMA3.0 with switch fabric
GIPO
6 high-speed
C64x+ CPUs
• Small Footprint allows
high board density
• 24x24, FC-BGA
10/100/1G
Ethernet
DSP-based system
provides programmability,
flexibilty, extensibility.
TMS320C6472 block diagram.
Medical Applications Guide
89
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
High-Performance Processor Integrates Three 1GHz Cores
TMS320C6474
Get samples, datasheets, tools and application reports at: www.ti.com/sc/device/TMS320C6474
TMS320C6474
C64x+
Core
C64x+
Core
L1 Data
L1 Data
L1 Data
L1 Prog
L1 Prog
L1 Prog
L2 Memory
L2 Memory
L2 Memory
C64x+™
Core
Applications
• Medical imaging
• High-performance systems
• Multichip system designs
• Projects with stringent power
budgets
EDMA 3.0 with Switch Fabric
GPIO
PLL
Timers Others
I2C
Boot
ROM
McBSP DDR-2
IF
10/100/
1G
Ethernet
TCP2
• Delivers 3x the raw DSP processing
performance
• Gain in raw performance: 50 percent
per watt
• Integrates three 1.2GHz cores on a
single chip
• Multiple-channel processing
capabilities
• Serial/deserializer (SERDES)
interfaces
• L1 program and L1 data memory per
core: 32KB
• DDR2 memory interface: 667MHz
• Process shrink to 65nm feature size
The TMS320C6474 multicore digital signal processor (DSP) saves cost, power and
board space by integrating three industry-leading cores running at 1GHz, each on
a single die. The C6474 delivers up to 1.2GHz of raw DSP performance that consumes one-third less power at two-thirds less DSP cost over discrete processing solutions. This DSP provides significant system integration for designers using
DSP farms in various applications.
VCP2
Key Features
Serial
Antenna
Interface RapidIO
TMS320C6474 DSP block diagram.
TMS320C645x DSP Generation, Fixed-Point Highest Performance DSPs
TMS320C6455
Get samples, datasheets, tools and application reports at: www.ti.com/sc/device/TMS320C6455
Key Features
• Based on the new TMS320C64x+™ core
720MHz, 850MHz, 1GHz, 1.2GHz
• Memory:
• 32KB L1D, 32KB L1P cache/SRAM
• 2MB L2, 256K cache/SRAM,
remainder SRAM only
• Acceleration:
• Viterbi decoder coprocessor (VCP)
• Turbo decoder coprocessor (TCP)
• Peripherals:
• Serial RapidIO: 10GbPs full duplex
• Two EMIFs: 32-bit DDR2, 64-bit
EMIF
Medical Applications Guide
TMS320C64x+™ DSPs (including the TMS320C6455) are the highest per­formance,
fixed-point DSP generation in the TMS320C6000™ DSP platform. The C6455 IC is based on the third-generation, high-performance, advanced VelociTI™ very-long
­instruction-word (VLIW) architecture developed by TI. This allows these DSPs to be used for applications including medical imaging, video and telecom infrastructure, imaging, and wireless infrastructure (WI). The C64x+™ ICs are upward
code-compatible from previous ICs that are part of the C6000™ DSP platform.
• Other high-bandwidth peripherals:
Gigabit Ethernet MAC, UTOPIA,
PCI-66, HPI
90
Applications
• Ultrasound
• Digital X-ray
• Medical imaging
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Industry’s Lowest Power Floating-Point DSPs
TMS320C6747
Get samples, datasheets, tools and application reports at: www.ti.com/sc/device/TMS320C6747
Key Features
The TMS320C6747 DSP combines low power and high precision to give
designers the freedom to bring portability to medical and other applications
requiring the precision, wide dynamic range and time-to-market benefits of
floating-point DSPs. Using three times less power than existing floating-point
DSPs, C674x devices support 32-bit single-precision and 64-bit double-
precision floating-point architecture and are the industry’s lowest power floating-point DSPs.
• Industry's lowest power floatingpoint DSPs
• High precision and wide dynamic
range enabled through the 32-/64-bit
accuracy of the floating-point DSP
core
• Portability for traditionally wired
applications through low power and
rich connectivity peripherals
• Reduced system cost through high
feature integration and low pricing
• Up to 20x lower standby power and one-third the power consumption of existing floating-point devices
Applications
• Portable ultrasound
• Industrial
• Conference phones
• Music effects
System Control
Input
Clock(s)
TAG Interface
PLL/Clock
Generator w/OSC
GeneralPurpose
Timer
Security Key Manager
Security Controller
Memory Protection
I/O Protection
GeneralPurpose
Timer
(Watchdog)
DSPSubsystem
Power/Sleep
Controller
C674x™
DSP CPU
RTC/
Pin
32-kHz
OSC Multiplexing
AET
32-KB
L1 Pgm
32-KB
L1 RAM
256-KB L2 RAM
1024-KB L2 ROM
Switched Central Resource (SCR)
Peripherals
DMA
Audio Ports
EDMA3
McASP
w/FIFO
(3)
Serial Interfaces
2
Control Timers
ePWM
(3)
eCAP
(3)
SPI
(2)
I C
(2)
UART
(3)
Connectivity
eQEP
(2)
USB2.0
OTG Ctlr
PHY
USB1.1
OHCI Ctlr
PHY
(10/100)
EMAC
(RMII)
MDIO
Display
Internal Memory
LCD
Ctlr
128-KB
RAM
Eternal Memory Interfaces
HPI
MMC/SD
(8b)
EMIFA(8b/16B)
NAND/Flash
16b SDRAM
EMIFB
SDRAM Only
(16b/32b)
TMS320C6747 DSP block diagram.
Medical Applications Guide
91
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Digital Media Processor
TMS320DM355
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/TMS320DM355
Key Features
• High-performance digital media
processor
• Fully software-compatible with
ARM9™
• 216MHz and 270MHz ARM926EJ-S™
core
• TI’s DaVinci™ software technology
• MPEG-4/JPEG coprocessor
• Video processing subsystem
• 16-bit-wide DDR/mDDR SDRAM
EMIF with 256MB address space
• MMC and SD/SDIO flash card
interface
• USB, UART, SPI and I2C peripherals
• Up to 104 configurable general-
purpose I/Os (GPIOs)
Applications
• Multiparameter patient monitors
• Portable ultrasound
• Automatic external defibrillator (AED)
• Electrocardiogram (ECG)
The TMS320DM355 is a highly integrated, programmable platform ideal for developing low-cost portable medical video applications. With an ARM9™ processor
at its core, the DM355 high-perform­ance digital media system-on-chip (DMSoC)
leverages TI’s DaVinci™ technology to offer high-performance video MPEG-4 HD
(720p) codecs and JPEG codecs to users developing affordable, high-quality, lowpower video solutions. The DM355 has a video-processing subsystem (VPSS) with
a configurable video-processing front end (VPFE) to interface with CCD/CMOS
imager modules or video decoders; a configurable video-processing back end
(VPBE) used for hardware on-screen display (OSD) support; and composite NTSC/
PAL and digital LCD output. In addition, the DM355 peripheral set includes a range
of interfaces such as USB, I2C, audio serial ports (ASPs), UART, serial peripheral
interface (SPI), external memory interface (EMIF) and GPIOs. With a complete
range of ARM® development tools including C compilers, assemblers and a
Windows® debugger interface for visibility into source-code execution, the DM355
offers a low-cost portable video alternative for medical devices.
For medical applications that do not require video, the lower-cost DM335 is a good
alternative without the video acceleration.
Video Processing Subsystem
TMS320DM355
ARM926
Subsystem
ARM926EJ-S™
216/270MHz
CPU
MPEG-4/
JPEG
Coprocessor
(MJCP)
Front End
Preview
Histogram/3A
CCD Controller
Video Interface
Resizer
Back End
Enhanced
Video
On-Screen
Enc
Display
(VENC)
(OSD)
MPEG- 4
JPEG
10b DAC
DMA/Data and Configuration Bus
Peripherals
EDMA
Serial Interfaces
ASP
×2
I2C
SPI
×3
UART
×3
Connectivity
System
USB
2.0
HS
OTG
Timer WD PWM
×6 Timer ×4
Program/Data Storage
MDDR2/
DDR2
EMI F
NAND/
ECC
EMIF
MMC/
SDIO
×2
TMS320DM355 processor.
Medical Applications Guide
92
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
High-Performance Applications Processor
OMAP3530
Get samples, datasheets, tools and application reports at: www.ti.com/sc/device/OMAP3530
Key Features
• OMAP3530/25 applications
processor
• Advanced very-long-instruction-word
(VLIW) TMS320C64x+™ DSP core
• C64x+™ L1/L2 memory architecture
• C64x+ instruction set features
• ARM® Cortex-A8 core
• ARM Cortex-A8 memory architecture
• 112KB ROM
• 64KB shared SRAM
OMAP3530 and OMAP3525 are high-performance applications processors based
on the enhanced OMAP™ 3 architecture. The OMAP 3 architecture is designed to
provide best-in-class video, image and graphics processing sufficient to support
streaming video, 2-D/3-D mobile gaming, video conferencing and high-resolution
still image. It also supports video capture in 2.5G wireless terminals, 3G wireless
terminals, rich multimedia-featured handsets and high-performance personal digital assistants (PDAs). Applications
• Ultrasound
• Ultra mobile devices
• Portable data collection
• Digital video camera
OMAP™ Applications Processor
IVA 2.2 Subsystem
TMS320DM64x+™ DSP
Imaging Video and
Audio Processor
32K/32K L1$
48K L1D RAM
64K L2$
32K L2 RAM
16K L2 ROM
Video Hardware
Accelerators
64
32
Async
64
LCD Panel
MPU
Subsystem
ARM-A8
Core
16K/16K L1$
DualCamera
(Serial and
Parallel)
Amp
Parallel
2-D/3-D
Graphics
Accelerator
(3530 only)
L2$
256K
64
64
CVBS
or
S-Video
32
Dual Output 3-Layer
Display Processor
(1xGraphics, 2xVideo)
Temporal Dithering
SDTV QCIF Support
32Channel
System
DMA
32
32
Camera
ISP
Image
Capture
Hardware
Image
Pipeline
and
Preview
TV
32
32
64
HS USB
Host
(with USB
TTL)
HS
USB
OTG
32
Async
32
64
64
L3 Interconnect Network-Hierarchail, Performance, and Power Driven
32
32
64K
On-Chip
RAM
2KB
Public/
62KB
Secure
112K
On-Chip
ROM
80KB
Secure/
32KB
BOOT
64
SMS:
SDRAM
Memory
Scheduler/
Rotation
SDRC:
SDRAM
Memory
Controller
32
GPMC:
GeneralPurpose
Memory
Controller
NAND/
NOR
Flash,
SRAM
External and
Stacked Memories
32
32
L4 Interconnect
Peripherals:
3xUART, 3xHigh-Speed I2C
5x McBSP
(2x with Sidetone/Audio Buffer)
4xMcSPI, 6xGPIO,
3xHigh-Speed MMC/SDIO,
HDQ/1 Wire,
2xMailboxes
12xGPTimers, 2xWDT,
32K Sync Timer
System
Controls
PRCM
2xSmartReflex™
Technology
ControlModule
External
Peripherals
Interfaces
Emulation
Debug: SDTI, ETM, JTAG,
Coresight DAP
OMAP3530 functional diagram.
Medical Applications Guide
93
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Analog Front Ends
AFE5801
*Page 81
8-Channel Integrated
Analog VCA, PGA, LPF and
12-bit, 65 MSPS ADC
AFE5804
*Page 82
8-Channel Integrated
Analog LNA, VCA,
PGA, LPF and 12-bit,
50-MSPS ADC
AFE5805
*Page 82
8-Channel Integrated
Analog LNA, VCA,
PGA, LPF and 12-bit,
50-MSPS ADC
AFE5851
*Page 81
16-Channel Integrated
Analog VCA, PGA, LPF and
12-bit, 65-MSPS ADC
OPAx695
50mW/channel at 30MSPS, 58mW/channel at
50MSPS, 64-pin 9 x 9 QFN package
Low power enables handheld ultrasounds
AFE5851
Enables portability, greater number of
channels per system and maintains good
image quality
AFE5805, VCA8500 with
ADS5281
Enables portability, greater number of
channels per system and maintains good
image quality
AFE5804
39mW/channel at 32.5MSPS, 64-pin 9 x 9 QFN
package
High channel count and low power allows
increased channel density in handheld
ultrasounds
AFE5801
High-Speed Op Amp
G = +2 BW 1400MHz, G = +8 BW 450MHz,
4300V/µs SR
Ultra-wideband, current feedback
OPA2695 (dual)
OPAx832
Video Buffer Op Amp
OPA2832 (dual)
VFB Op Amp
OPA211
Precision Op Amp
G = +2 BW 80MHz, 3.9mA supply, 350V/µs SR
—
3.9GHz GBW, 0.85nV/√Hz noise, 950V/µs SR
—
1.1nV/√Hz noise at 1kHz, ±2.25V to ±18V supply,
80MHz BW
Low power, fixed gain
OPA847
OPA369
Nanopower ZeroCrossover Op Amp
OPA695
*Page 86
Ultra-Wideband, CurrentFeedback Operational
Amp
OPA2695
*Page 87
—
101mW/channel low power, 1.23nV/√Hz low noise,
135-pin 15 x 9 BGA package
—
122mW/channel low power, 0.85nV/√Hz low noise,
135-pin 15 x 9 BGA package
Amplifiers
High DC accuracy, stable for gains >12V/V
Unity gain stable, RRO, wide supply range
OPA227
1.8V to 5.5V, 700nA IQ, CMRR 114dB RRIO, 0.4µV/°C,
Vos drift
±4.2V output voltage swing, low disabled power of
0.5mW, ultra-high slew rate
Zero-crossover input offers excellent CMRR
over entire input range
OPA379, OPA349
Dual, Wideband, CurrentFeedback Operational
Amp
±4.2V output voltage swing, low quiescent current,
low disable current
Optimized for high gain operation
OPA2889
*Page 87
High-Speed Op Amp
460µA/channel quiescent current
Very low power
OPA2890
THS4131
High-Speed Op Amp
THS4120, THS4150
High-Speed Op Amp
150MHz (–3dB) BW, 51V/µs SR, –100dB THD
—
3GHz BW, 830V/µs SR, 2.4nV/√Hz noise, 7.5ns
settling time (001%)
Differential input/differential output
THS4304
High bandwidth and fast settling time
THS4509
High-Speed Op Amp
1900MHz BW, 6600V/µs SR, 2ns settling time (1%)
Low distortion, fully differential
THS4508, THS4511
THS4524
Very Low Power Quad
Channel Rail-to-Rail
Output Fully Differential
Amplifier
Fully differential, 1.14-mA/ch current consumption
Low power signal conditioning
THS4521
TPA2010D1
Analog-Input
Class-D Amp
2.5W mono, fully differential, filter-free Class D, in
WCSP
Loud audio, long battery life, small package
size
TPA2031D1
TPA2013D1
Analog-Input
Class-D Amp
2.7W constant output power, mono, Class D,
integrated boost converter
Louder audio at low battery levels
TPA2014D1
TPA4411
Audio Headphone Amp
Audio headphone amp
TPA6205A1
Class-AB Audio Amp
1.25W mono, fully differential, Class AB
Loud audio, low cost
TPA6211A1
Class-AB Audio Amp
Loud audio
VCA2615
Dual, Low-Noise LNA
and VCA
3.1W mono, fully differential, Class AB
—
Very low noise: 0.7nV/√Hz
For high-end systems requiring high dynamic
range and flexibility
VCA2611
VCA2617
Dual, Low-Power VCA
Differential I/O VCA, low power: 52mW/ch
Low-power, low-noise VCA to follow an
off-chip LNA
VCA2614
VCA8500
*Page 85
8-Channel Ultra­sound
Front End
Complete with LNA,
— VCA and LPF; low noise and
power: 0.8nV/√Hz and 65mW/ch
Best-in-class noise-power combination
AFE5805
VCA8613
8-Channel Ultra­sound
Front End
Complete with LNA, VCA and LPF; low power:
75mW/ch
Best-in-class power
VCA8500
VCA8617
8-Channel Ultra­sound
Front End
Complete
—with LNA, VCA and LPF; low noise of
1.0nV/√Hz
Best-in-class noise
VCA8500
TPA6130A2
TPA6204A1
New products are listed in bold red.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Gives more than adequate 0.8ns rise time for
a 2V output step for the highest speed video
requirements
94
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Data Converters
ADS1610
Delta-Sigma ADC
16-bit, 10MSPS, parallel interface
SYNC pin for simultaneous sampling
ADS1605
Delta-Sigma ADC
16-bit, 5MSPS (10MSPS in 2x mode), 88dB SNR,
–99dB THD
Selectable on-chip reference
ADS5121
High-Speed ADC
8-channel, 10-bit, 40MSPS, 1.8V analog/digital
supply
Low power, individual channel power down
ADS5232
High-Speed ADC
Dual 12-bit, 65MSPS, 3.3V analog/digital supply
Internal or external reference
ADS5240
High-Speed ADC
4-channel, 12-bit, 65MSPS, 3.3V analog/digital
supply
Serialzed LVDS outputs, integrated frame and
bit patterns
ADS5242
ADS5281
*Page 84
High-Speed ADC
8-channel, ultra-low-power, 12- and 10-bit, 50 to
65MSPS analog-to-digital converter
77mW per channel, serialized LVDS outputs,
1/F noise-suppression
ADS5282, ADS5287
ADS5282
*Page 84
High-Speed ADC
Ultra-low-power, 8-channel, 12-bit, 65MSPS
77mW per channel, serialized LVDS outputs,
1/f noise suppression
ADS5281
ADS5287
*Page 84
High-Speed ADC
Ultra-low-power, 8-channel, 10-bit, 65MSPS
77mW per channel, serialized LVDS outputs,
1/f noise suppression
ADS5281
ADS7809
AR ADC
16-bit, 100kHz sample rate, 86dN SINAD with
20kHz input, serial ouput
Output sync pulse for ease of use with
standard DSP processors
ADS8284
SAR ADC
18-bit, 1MSPS, 4 MUX inputs, 98.5dB (typ) SNR at
10kHz
Integrated op amp, ultra-high DC and AC
performance
ADS8380
SAR ADC
18-bit, 600kHz sample rate, ±2 LSB (typ), pseudodifferential input
Zero latency, serial interface with clock up to
40MHz
ADS8422
SAR ADC
16-bit, 4MSPS, parallel w/reference, pseudo bipolar,
fully differential input
Low power
ADS8484
High-Speed SAR
18-bit, 125MSPS, 98dB (typ) SNR, –110dB (typ) THD
Excellent drift performance
ADS8519
Bipolar ADC
±10V bipolar, 16-bit, 250kSPS, 10mW at
250kSPS (typ)
Flexible voltage digital interface supports
1.8V I/O
DAC2900
High-Speed DAC
10-bit, 125MSPS dual DAC
Supports 3.3/5V
DAC2902, DAC2904
DAC7568
12-Bit Octal Channel,
Ultra-Low Glitch, Voltage
Output DAC With 2.5V,
2-ppm/°C Internal
Reference
DSP-compatible 3-wire serial interface with power
on reset and power down features
Useful for portable ultrasound data conversion
DAC8168, DAC8568
DAC8168
14-Bit Octal Channel,
Ultra-Low Glitch, Voltage
Output DAC With 2.5V,
2ppm/°C Internal
Reference
DSP compatible 3-wire serial interface with power on
reset and power down features
Useful for portable ultrasound data conversion
DAC7568, DAC8568
DAC8560
VOUT DAC
16-bit, 0.15nV-s glitch, ±10µs to 0.003% FSR
settling time
Small package, low power
DAC8554, DAC8551,
DAC8552
DAC8568
16-Bit Octal Channel,
Ultra-Low Glitch, Voltage
Output DAC With 2.5V,
2ppm/°C Internal
Reference
DSP compatible 3-wire serial interface with power on
reset and power down features
Useful for portable ultrasound data conversion
DAC7568, DAC8168
DAC8330
Precision DAC
16-bit, VOUT, 1LSB INL
Very low power, serial interface
DAC8331, DAC8830
DACx311
8 to 16-Bit, Single
Channel, Low Power,
Ultra-Low Glitch DAC
±2 LSB, scalable output range, SPI interface with
1.8V to 5.5V logic
Very low noise and fast settling time
REF02
Precision VREF
0.2% (max) initial accuracy, 10ppm/°C (max) drift,
1.4mA (max)
Excellent line/load regulation, low noise
REF30xx
Low-Power, Low-Drift
Series Reference
REF31xx
Voltage Reference
50µA, 0.2% initial accuracy, 50ppm/°C max drift,
±25mA output, 1.25V, 2.048V, 2.5V, 3.0V , 3.3V,
4.096V
15ppm/°C (max) drift, 5mV low dropout, 115µA (max)
IQ, 0.2% (max) accuracy, 1.25V, 2.048V, 2.5V, 3.0V,
3.3V, 4.096V
ADS5122
References
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
REF5050
REF31xx, REF33xx,
REF29xx
No load capacitor required
REF32xx, REF33xx
New products are listed in bold red.
95
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
References (continued)
REF32xx
Low Drift, Bandgap
0.2% (max) accuracy, 7ppm/°C (max) drift, 0.1mA
(max) IQ
Multiple output voltages, SOT23-6
REF33xx
Very-Low-Power Series
Reference
5µA, 0.15% initial accuracy, 30ppm/°C max drift,
±5mA output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V, 3.3V
Preserves battery life, fits into physically
constrained systems
REF30xx, REF31xx,
REF29xx
REF5010
Low Noise, Very-LowDrift, Precision Voltage
Reference
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 10V
Improves system accuracy
REF102
REF50xx
High-Precision,
Very-Low-Drift Series
Reference
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 2.048V, 2.5V, 3.0V, 4.096V, 4.5V, 5.0V
Improves system accuracy
REF02
OMAP3530
*Page 93
TMS320C6452
Applications Processor
TMS320C6455
*Page 90
TMS320C6472
*Page 89
TMS320C6474
*Page 90
TMS320C6745
DSP
1.2GHz, SRIO, 2MB RA
DSP
6x 700MHz C64x+ cores, 4.8MB RAM, SRIO, HPI
Laptop-like performance at handheld power
levels
High-performance DSP with improved
system cost
High-performance, fixed-point 16-bit
processor
High-performance multiprocessor solution
OMAP3503, OMAP3515,
OMAP3525
DSP
ARM® Cortex A-8, C64x+™, graphics accelerator,
video accelerators
900MHz, 1.4MB L2 cache, 2x SGMII/Gigabit EMAC
DSP
3x 1.2GHz C64x+ cores, 3MB RAM, SRIO
High-performance multiprocessor solution
DSP
1800MFLOPS, 256KB L2
TMS320C671x
Industry's Lowest Power
Floating-Point DSPs
Highly Integrated,
Programmable Platform
for Low Cost Portable
Digital Video Apps
Highly Integrated Video
SoC
32-/64-bit accuracy, 1.8V to 3.3V I/O supply, low
power and rich connectivity peripherals
ARM926 at 216/270MHz; MPEG4 HD (720p) and
JPEG up to 50M pixels per second
Low cost floating point, combines C64x+ and
C67x cores
Uses three times less power than existing
floating-point DSPs
High quality, low-power consumption at low
price
High quality, low-power consumption at low
price
TMS320DM6443,
TMS320DM6441
With dedicated, high precision peripherals,
Piccolo microcontrollers are the ultimate
combination of performance, integration, size,
and low cost. Ideal for precision sensing and
control applications.
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point
brings increased performance and quicker
development. Ideal for precision sensing and
control applications.
TMS320F283x Delfino,
TMS320F280x
Processors
TMS320C6747
*Page 91
TMS320DM355
*Page 92
TMS320DM6446
*Page 88
Robust operating systems support, rich user
interfaces, high processing performance, and long
battery life
Up to 60MHz C28x™ core with optional control
law accelerator. Up to 128KB Flash, high resolution
(150ps) PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
TMS320C6454BZTZ
TMS320DM365,
TMS320DM368
TMS320F2802x/3x
Piccolo™
32-Bit Microcontroller
TMS320F283x
Delfino™
32-Bit Floating-Point
Microcontroller
Up to 300MHz C28x™ core. Up to 512KB Flash, high
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN,
QEP, external memory bus, DMA.
SN65LVDS387
SN65LVDS93A
16-Channel LVDS Driver
24-Bit RGB LVDS Serdes
4-Channel M-LVDS Driver
High-density LVDS driver
Wide frequency range, saves space, no level
shifter for 1.8V powered uP
Industry standard
SN65LVDS386
SN75LVDS83B
SN65MLVD047
630Mbps
10MHz-135MHz, BGA and TSSOP; supports 1.8V to
3.3V TTL i/p
Higher differential swing
RMS jitter <1ps, recommended clocking solution for
AFE580x and ADS528x/527x
Recommended clocking solution for TI DSPs
Recommended clocking solution for TI DSPs
Integrated VCO saves system cost
CDCE72010, CDCM7005
0ppm multiple-frequency generation
0ppm multiple-frequency generation
CDCE(L)937, CDCE(L)925
CDCE706
Impedance Track Technology, Supports the Smart
Battery SBSV1.1 specification
Provides better than 1% error over lifetime of
Li-Ion and Li-Polymer Batteries
bq20Z95
Multichemistry and multicell sync switch-mode
charger
Designed for managing 3- to 8-series cell battery
systems, high-resolution 18-bit integrating deltasigma Coulomb Counter for precise charge-flow
measurements and gas gauging
High efficiency, pack and system protection
functions
Expandable from 3 – 12 Li-Ion cells in series,
active cell balancing
bq24105
TMS320F2802x/3x
Piccolo, TMS320F280x
Interface
SN65LVDS348
Clocking
CDCE62005
Clock Generator
CDCE(L)949
CDCE906
Clock Synthesizer
Clock Synthesizer
Power Management
bq20z40-R1
bq24721
bq78PL114
SBS-Compliant Gas
Gauge with Impedance
Track™ Technology for
use with BQ29330
Battery Charge
Management
High Power and High
Capacity Battery Pack
Management Controller
New products are listed in bold red.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
bq76PL102
96
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (continued)
DCH010505
DCP01B
PTB48500A
PTH04T240
Galvanic Isolated, DC/DC
Converters
DC/DC Converter
DC/DC Converter
Power Module
1W, 3kV isolation, minimal external components
Safety isolation, removal of ground loops,
reducing board space
1W POUT or IOUT, ±5V, ±12V, ±15V VO range
30W POUT to IOUT, 3.3V/1.2V VO range
Complete power supply designed to meet
ultra-fast transient requirements
Complete power supply designed to meet
ultra-fast transient requirements
Two fixed and one adjustable supervisor for
system flexibility
DCH010512, DCH010515
PTH08T220
Power Module
TPS3307
Voltage Supervisor
5V, 15V, 24V input bus, 1W, unregulated, dual, isolated
48V input bus, 30W, dual, isolated
10A, 2.2V to 5.5V VIN, adjustable VOUT, with
TurboTrans™ Technology
16A, 4.5V to 14V VIN, adjustable VOUT, with
TurboTrans Technology
Triple processor supervisor
TPS386000
4-Channel Supervisor
0.25% acc, down to 0.4V, watchdog
High integration and high accuracy
TPS54317
DC/DC Converter
3.0 to 6.0VIN 3A DC/DC with integrated switch FET,
synchronization pin, enable
Eliminate beat noise/ceramic caps/FPGA/
integration
TPS3808
TPS54350
DC/DC Converter
4.5 to 20VIN 3A DC/DC with integrated switch FET,
synchronization pin, enable
Eliminate beat noise/ceramic caps/FPGA/
integration
TPS62110
DC/DC Converter
3.1 to 17VIN 1.5A DC/DC with integrated switch FET,
synchronization pin, enable, Low battery indicator,
PFM mode
Very low noise/high efficiency
TPS62400
Dual Output Step-Down
Converter
180° out of phase operation, serial interface
Flexible voltage adjustment for processors
and MCUs
TPS62420
TPS63000
Buck-Boost Converter
1.8A switch, automatic transition between step down
and boost mode
Stable output voltage over entire entire VIN
range
TPS63010
TPS65073
PMU with charger and
WLED
Integrates charger, WLED, DCDC and LDO.
Highest integration for portable applications
TPS650250
DCP02
PTB48501A/B
PTH04T241
PTH08T221
TPS3808
TPS54550
TPS727xx
Single Channel LDO
High PSRR/low noise/ultra low IQ
Battery power applications
TPS717xx
TPS7A45xx
Single Channel LDO
High PSRR/low noise/ultra low IQ
High Performance with VIN < = 20V
TL1963xx
TPS74201
Single-Channel LDO
1.5A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat
TPS74301, TPS74801
TPS74401
Single-Channel LDO
3.0A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat
TPS74901
TPS74701
Single-Channel LDO
0.5A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat
UCD90120
12-Channel Sequencer
GUI for programming 12 power rails
Sequencing, monitoring and margining
UCD9081, UCD90124
Pulsers and Switchers
TX734
*Page 83
Quad-Channel, HighVoltage Ultrasound pulser
Quad, 3-level RTZ, ±100V, ±75V, 2A integrated
ultrasound pulser
Low-noise operation
TX810
TX810
*Page 83
8-Channel Integrated T/R
Switch
Eight bias current settings; eight power/performance
combinations; accepts 200VPP input signals
Compact T/R switch; flexible programmability;
easy power-up/down control; fast wakeup time; dual supply operation; optimized
insertion loss
TX734
±1°C remote diode sensor with ±1°C local temp
sensor
Recommended for FPGA Temp monitoring in
ultrasound
TMP421
Temperature Sensor
TMP441
±Temperature Sensor
with Automatic Beta
Compensation, Series-R
and n-Factor in a
8-pin SOT23
Toolkits
STK-MED
*Page 126
A collection of several
standard ultrasound
algorithms optimized
for TI’s C64x+ DSP
architecture
Standard APIs; tested, benchmarked and documented
library modules
Shortens customer development time by
providing highly opttimized C64x+ DSP source
code of common ultrasound processing blocks
DLP®
Discovery™ 4100
An optical semiconductor
module that allows digital
manipulation of light
±12° mirror operation, works with Visible, UV and
near-IR light
This device can surpass the speed, precision
and efficiency of other spatial light modulators
DLP® Pico™
DLP® Pico™ Kit
Projector Development
Kit that fully integrates
projection solutions for
a vast array of portable
medical devices
44.8x67.4x14.2mm3, I2C command interface
Well suited for incorporating digital projection
into portable devices
DLP® Discovery™
New products are listed in bold red. Preview products are listed in bold blue.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
97
Texas Instruments 2010
Medical Imaging
➔ Ultrasound
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
CC1101
Sub-1GHz RF Transceiver
Wake-on-radio functionality; integrated packet
handling with 64B data FIFOs; high RF flexibility: FSK,
MSK, OOK, 1.2-500kbps; extremely fast PLL turn-on/
hop time
Ideal for low-power systems; any low-end
MCU can be used; backwards-compatible with
existing systems; suitable for fast frequencyhopping systems
CC2500
CC2520
2.4GHz ZigBee/IEEE
802.15.4 RF Transceiver
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended
temperature range; AES-128 security module
Reliable RF link with interference present; 400
m line-of-sight range with the development
kit; ideal for industrial applications; no external
processor needed for secure communication
CC2530
2.4GHz Bluetooth® 2.1
chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital
radio processor technology.
MCU, USB 2.0, flash and RAM in one package;
four flexible power modes for reduced power
consumption; includes CC1101 transceiver frequency
synthesizer; built-in AES-128 encryption coprocessor
Sophisticated low-power technology ideal for
battery operated solutions
Complete low-cost solution on single chip;
ideal for low-power battery-operated systems;
robust and secure link with good noise
immunity; no external processor needed for
secure communication; can connect directly
to a PC
CC2530/31
Second Generation
System-on-Chip Solution
for 2.4GHz IEEE 802.15.4/
RF4CE/ZigBee
Excellent Rx sensitivity, low power, easy to use
development tools
RF design made easy for fast time to market;
provides a robust and complete ZigBee USB
dongle or firmware-upgradable network node
CC2540
2.4GHz Bluetooth® Low
Energy compliant RF
System-on-Chip
2.4GHz 802.11b/g/n and
Bluetooth® 2.1 Chipset
Excellent link budget enabling long range
applications without external frontend, receiver
sensitivity, selectivity and blocking performance
Single-chip 802.11b/g/n WLAN and Bluetooth®
solution using TI’s digital radio processor technology
using a single antenna.
A fast-to-market Bluetooth® low energy
compliant solution
2.4/5GHz 802.11a/b/g/n
and Bluetooth® 2.1
Chipset
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
RF ICs
RF Transceivers
RF Systems-on-Chip
CC2560
CC1110/11
WL1271
WL1273
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
Sophisticated low-power technology ideal
for battery operated solutions; coexistence
features enable simultaneous WLAN and
Bluetooth® operations; supports ANT+
standard.
CC2510, CC2511
CC2590/91, CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Second Generation
Z-Stack™ Network
Processor
ZigBee® stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings; excellent selectivity and blocking
performance
New products are listed in bold red. Preview products are listed in bold blue.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Add CC2530ZNP and your system is ZigBee
enabled; ideal for battery operated systems;
excellent coexistence with Bluetooth®
technology and Wi-Fi.
98
Texas Instruments 2010
Medical Imaging
➔ CT Scanners
Computed Tomography
Computed tomography (CT) is a medical imaging technique that produces three-dimensional images of internal human body parts from a
large series of two-dimensional X-ray
images (called profiles) taken in a single-axis rotating structure called a
gantry. When compared to a conventional X-ray radiograph, which is an
image of many planes superimposed
on each other, a CT image exhibits
significantly improved contrast.
With the advent of diagnostic imaging
systems like CT, where complex and
intensive image processing is required,
semiconductors play a very important
role in developing systems with increased
density, flexibility and high performance.
X-ray slice data is generated using an
X-ray source that rotates around the
object, with X-ray detectors positioned
on the opposite side of the circle from
the X-ray source. Many data scans are
taken progressively as the object is
gradually passed through the gantry. The newer helical or spiral CT machines
that use faster computer systems and
optimized software can continuously
process the cross-section images
while the object passes through the
gantry at a constant speed.
Motion Control Unit
X-Ray Tube
The channel card has a front-end system where charge on the detectors
are integrated, gained by amplifiers
and converted to digital values by
ADCs. The digital data from all channel cards is transferred by high-speed
link to the controller card and onto the
image conditioning cards. The image
conditioning card is connected to the
host computer where the CT images
can be viewed. Here, the digital data
are combined by the mathematical
procedure known as tomographic
reconstruction. Power supplies, clocks
and clock distribution circuits, reference and reference buffers, logic, and
interface products are some of the key
blocks in the channel card subsystem.
Product portfolio for CT scanners
• Channel card front end and control
card subsystems, including data
converters, processors, power management solutions and other analog
products.
• Single-chip solutions for directly
digitizing low-level currents from
photodiode arrays in CT scanners.
• DSPs with TI’s VelociTI™ VLIW architecture can provide accurate control
of the gantry rotation, the movement
of the table, the tilting of the gantry
for angle images, and other real-time
control and processing functions.
• Voltage supervisors, DC/DC converters,
non-isolated power modules and
low-dropout linear regulators to meet
sequencing requirements.
Control cards can include DSPs and
FPGAs, power supplies, clocks and
clock distribution circuitry and
Channel Card Front-End
Controller Card
Signal
Processing
Gantry
X-Ra
ys
interface blocks. DSPs can be used to
provide accurate control of the gantry
rotation, the movement of the table
(up/down and in/out), tilting of the
gantry for angled images, and other
functions such as turning the X-ray
beam on and off. Another important
DSP control functionality is ECG gating
used to reduce motion artifacts caused
by heart movement. Here, the data
acquisition is carefully synchronized
with the heartbeat.
The detector system consists of a
number of channel cards that have
scintillator-photodiode solid state
detectors. The X-rays interact with the
scintillator and produce visible light,
which is in turn converted into a current by the photodiode. The depth
information along the direction of the
X-ray beam that is lost in radiography
is recovered by viewing the slide from
many different directions.
Line
Drivers
AFE
A
Detectors
ADC
DSP
And/Or
FPGA
Core and
I/O Power
Image
Reconstruction
AC Line
Isolated
AC/DC
Supply
System
Power
REF
DSP
And/Or
FPGA
Wireless
Medical
System
and PC
Interfaces
Level Shift
Temp Sense
Fan Control
SDRAM
Plug
Logic
Power Management
FLASH/
EPROM
Low Noise
Power
Clock
LEGEND
Memory
Power
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
CT scanner system block diagram.
Medical Applications Guide
99
Texas Instruments 2010
Medical Imaging
➔ CT Scanners
Dual, Current-Input, 20-Bit ADC
DDC232
Get samples, datasheets, application reports and evaluation modules at: www.ti.com/sc/device/DDC232
Key Features
• Complete solution for measuring 32
photodiodes with 20-bit resolution
• Continuous charge collection
• Adjustable integration time: 160µs to
more than 1s
• Programmable full scale: 12.5pC up to 350pC
• Low noise: 5ppm, rms
• Integral nonlinearity: ±0.025% reading ±1ppm FSR
• Single supply with 7mW/channel
power dissipation
• Serial digital interface with daisy
chaining support
• Packaging: 8mm x 8mm BGA
Applications
• CT scanners
• X-ray systems
• Photodiode sensor arrays
TI offers several products that can meet the needs of designers of medical imaging systems by enabling the measurement of low-level currents produced by the
photo­diode arrays within a computed tomography (CT) scanner.
The DDC products are single-chip solutions for directly digitizing low-level currents
from photodiode arrays in CT scanners. The dual-integrator front-end provides
continuous charge collection. While one integrator is collecting the photodiode
current, the other is being measured by the onboard 20-bit ADC. Integration time
is user-adjustable, and the output data is retrieved over a serial interface that can
be daisy chained to minimize digital interconnects in high-channel-count systems.
VREF
AVDD
IN1
IN2
DVDD
CLK
Dual
Switched
Integrator
+ ∆Σ
Modulator
–
Digital
Filter
Dual
Switched
Integrator
CONV
Configuration
and
Control
DIN_CFG
CLK_CFG
RESET
IN31
IN32
DVALID
Dual
Switched
Integrator
+ ∆Σ
Modulator
–
Digital
Filter
Serial
Interface
Dual
Switched
Integrator
DCLK
DOUT
DIN
AGND
DGND
DDC232 functional diagram.
IN1
DDC232
IN32
DOUT
Digital
Output
0101010
DIN
DOUT
IN1
DDC232
IN32
100
ADC
0101101…
DIN
Photodiode measurement using
the DDC232 ADC.
Medical Applications Guide
Dual Switched
Integrator
DDC architecture.
Texas Instruments 2010
Medical Imaging
➔ CT Scanners
Precision, High-Speed Transimpedance Amplifier
OPA380
Get datasheets and application reports at: www.ti.com/sc/device/OPA380
Key Features
• Over 1MHz TIA bandwidth
• Dynamic range: 5 decades
• Inherent long-term stability
• Output swing includes ground
• Very low 1/f noise
• Bias current: 50pA (max)
• Offset voltage: 2µV (max)
• Drift: 0.1µV°C
• Gain bandwidth: 90MHz
• Quiescent current: 6mA
• Supply range: 2.7V to 5.5V
• Single and dual versions
• Packaging: MSOP-8 and SO-8
The OPA380 transimpedance amplifier family provides high speed, high precision
and long-term stability. It exceeds the offset, drift and noise performance that conventional JFET op amps provide.
RF
+5V
OPA380
VO
0V to 4.9V
Photodiode
CDIODE
–
+
67pF
1MΩ
–5V
100
kΩ
Applications
• CT scanner front end
• Precision current-to-voltage
measurements
• Optical amplifiers
• Photodiode monitoring
RP
(Optional
Pulldown
Resistor)
20mV
75pF
OPA380 functional block diagram.
18-Bit, 1MSPS, Differential Input, microPower ADC with Parallel Interface
ADS8482
Get samples, datasheets, application reports and evaluation modules at: www.ti.com/sc/device/ADS8482
Key Features
• Sample rate: 0 to 1MHz
• INL: ±1.2LSB (typ); ±2.5LSB (max)
• DNL: +0.75/–0.6LSB (typ); +1.5/
–1LSB (max)
• 18-bit NMC ensured over temperature
• Offset error: ±0.05mV
• Offset error drift: ±0.05ppm/°C
• Zero latency
• Wide digital supply: 2.7V to 5.25V
• Low power: 225mW at 1MSPS
• Packaging: 48-lead QFN, 7 x 7mm
Applications
• Medical instruments
• Transducer interface
• High-accuracy data acquisition
systems
Medical Applications Guide
The ADS8482 is an 18-bit, 1MSPS ADC with an internal 4.096V reference and a
pseudo-bipolar, fully differential input. It features a full 18-bit interface, a 16-bit
hold option where data is read using two read cycles or an 8-bit bus option using
three read cycles. Other features include 99dB SNR, –121dB THD, 123dB SFDR,
onboard reference with 6ppm/°C drift and onboard reference buffer.
SAR
+IN
–IN
+
_
BYTE
16-/8 Bit
Parallel DAA
Output Bus
BUS 18/16
Comparator
REFIN
REFOUT
CDAC
Output
Latches
and
3-State
Drivers
4.096V
Internal
Reference
Clock
Conversion
and
Control Logic
CONVST
BUSY
CS
RD
ADS8482 functional block diagram.
101
Texas Instruments 2010
Medical Imaging
➔ CT Scanners
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifier
OPA2211
Lowest Power,
1.1nV/√Hz
Noise, Precision
Operational
Amplifier in DFN8 (3 x 3mm) and
SOIC-8
Extremely low voltage and low current noise, high
speed and wide output swing
Allows 16-bit accuracy throughout 10V output
swings
OPA627, OPA2111
OPA380
*Page 101
Transimpedance
Amp
90MHz GBW, over 1MHz transimpedance BW, 25µV
offset (max), 0.1µV/°C drift (max)
Precision, dynamic range 4 to 5 decades, excellent
long term stability
OPA350, OPA335
OPA827
Precision JFET
Op Amp
4nV/√Hz noise at 1kHz, ±4V to ±18V supply, 15pA (typ)
input bias current, 22MHz BW
High precision, low noise, low input bias, wide
supply range
OPA177, OPA627,
ADS8284
SAR ADC
18-bit, 1MSPS, 4 MUX inputs, 98.5dB (typ) SNR
at 10kHz
Integrated op amp, ultra-high DC and AC
performance
ADS8317
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff
inputs
Excellent linearity, micropower, high speed
ADS8422
ADS8326
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff
inputs
Low noise, low power, high speed
ADS8325
ADS8482
*Page 101
SAR ADC
18-bit, 1MSPS, 2.25mW power, 99dB SNR, ±2.5 LSB
(max) INL
Pseudo bipolar, internal or external reference
ADS8472, ADS8484
Data Converters
ADS8484
High-Speed SAR
18-bit, 125MSPS, 98dB (typ) SNR, –110dB (typ) THD
Excellent drift performance
DDC112
2 Channels
50 to 100pC full-scale
Up to 3kSPS data rate, 40mW/Ch
SOIC-28 or TQFP-32
DDC114
4 Channels
12.5 to 350pC full-scale
Up to 3.1kSPS data rate, 13.5mW/Ch
QFN-48
DDC118
8 Channels
12.5 to 350pC full-scale
Up to 3kSPS data rate, 40mW/Ch
QFN-48
DDC232 *Page 100
32 Channels
12.5 to 350pC full-scale
Up to 6kSPS data rate, 7mW/Ch
BGA-64
REF02
Precision VREF
Excellent line/load regulation, low noise
REF5050
REF102
10V, Ultra
Precision
Voltage
Reference
0.2% (max) initial accuracy, 10ppm/°C (max) drift,
1.4mA (max)
0.05% (max) initial accuracy, 2.5ppm/°C (max) drift,
1.4mA (max)
15ppm/°C (max) drift, 5mV low dropout,
115µA (max) IQ, 0.2% (max) accuracy, 1.25V, 2.048V,
2.5V, 3.0V, 3.3V, 4.096V
0.2% (max) accuracy, 7ppm/°C (max) drift,
0.1mA (max) IQ, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
5µA, 0.15% initial accuracy, 30ppm/°C max drift,
±5mA output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V, 3.3V
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 10V
Excellent stability and line/load regulation
REF5010
No load capacitor required
REF3130, REF3120
References
REF31xx
REF32xx
REF33xx
REF5010
REF50xx
Low Drift,
Bandgap
Very Low Power
Series Reference
Low Noise.
Very Low Drift,
Precision Voltage
Reference
High-Precision,
Very Low Drift
Series Reference
Multiple output voltages, SOT23-6
Preserves battery life, fits into physically
constrained systems
Improves system accuracy
REF30xx, REF31xx,
REF29xx
REF102
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 2.048V, 2.5V, 3.0V, 4.096V, 4.5V , 5.0V
Improves system accuracy
REF02
TMS320C6454BZTZ
Processors
TMS320C6455BZTZ
DSP
1.2GHz, SRIO, 2MB RAM
High-performance, fixed-point 16-bit processor
TMS320F2808
Digital Signal
Controller
100MIPS, 8KB ROM, 36KB RAM, 128KB flash, 12-bit
ADC
I2C, 4 SPI, 2 SCI, 2 CAN
TMS320F2812
Digital Signal
Controller
150MIPS, 8KB ROM, 36KB RAM, 256KB flash, 12-bit
ADC
McBSP, 1 SPI, 2 SCI, 1 CAN
TMS320F28015
Digital Signal
Controller
32-Bit
Microcontroller
60MIPS, 8KB ROM, 12KB RAM, 32KB flash, 12-bit ADC
I2C, 1 SPI, 1 SCI
Up to 60MHz C28x™ core with optional control law
accelerator. Up to 128KB Flash, high resolution (150ps)
PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
TMS320F283x
Delfino™
32-Bit
Floating-Point
Microcontroller
Up to 300MHz C28x™ core. Up to 512KB Flash, high
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN, QEP,
external memory bus, DMA.
TMS320C6474
DSP
3x 1GHz C64x+™ DSP cores, 3MB RAM, SRIO
With dedicated, high precision peripherals, Piccolo
microcontrollers are the ultimate combination of
performance, integration, size, and low cost. Ideal
for precision sensing and control applications.
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point brings
increased performance and quicker development.
Ideal for precision sensing and control applications.
High-performance multiprocessor solution
TMS320F2802x/3x
Piccolo™
TMS320F283x Delfino,
TMS320F280x
TMS320F2802x/3x
Piccolo, TMS320F280x
*For
additional product information see designated page number. To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
102
Texas Instruments 2010
Medical Imaging
➔ CT Scanners
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Interface
XIO1100
x1 PCIe PHY
Interface FPGA to PCIe fabric between channels
PCIe 1.1 compliant, flexible MAC interface
TLK1221
Gigabit Ethernet
Serdes
Power 250mW
Smallest package
SN65LVCP40
Dual 1:2 Mux/
Buffer
Input EQ, output pre-emp
Improves signal range
SN65LVDS93A
24-bit RGB LVDS
Serdes
10MHz-135MHz, BGA and TSSOP; supports 1.8V to
3.3V TTL i/p
Wide frequency range, saves space, no level shifter
for 1.8V powered uP
SN75LVDS83B
Very low additive jitter <100ps RMS; 2.5V / 3.3V
operation
Improved clock signal quality by 10x; saves
additional interface logic / external components
CDCLVP111, CDCLVP215
TLK2208B
Clocking
CDCLVP12xx/
21xx
1:2/4/8/12/16 or
Dual 1:2/4/6/8
Universal-toLVPECL Clock
Buffers
Analog Multiplexers
TS3A5017
Dual SP4T
3.3-V/2.5-V
Analog
Multiplexer/
Demultiplexer
Low total harmonic distortion
Excellent signal integrity in both digital and analog
applications
TS3A5018
Quad SPDT
3.3V/2.5V
Analog Switch
Low on state resistance and matching (RON = 10)
Minimizes signal loss and ensures less variance
Power Management
PTH04T240
Power Module
10A, 2.2V to 5.5V VIN, adjustable VOUT, with
TurboTrans™ Technology
Complete power supply designed to meet ultra-fast
transient requirements
PTH04T241
PTH08T220
Power Module
16A, 4.5V to 14V VIN, adjustable VOUT, with TurboTrans
Technology
Complete power supply designed to meet ultra-fast
transient requirements
PTH08T221
TPS3307
Voltage
Supervisor
Triple processor supervisor
Two fixed and one adjustable supervisor for system
flexibility
TPS3808
TPS386000
4-Channel
Supervisor
0.25% acc, down to 0.4V, watchdog
High integration and high accuracy
TPS3808
TPS40020
2.25V to 5.5V
DC/DC Controller
Synchronization pin, PG, enable
Eliminate beat noise/ceramic caps/FPGA/regulation
from main power supply
TPS40042
TPS40057
8V to 40V DC/DC
Controller
Synchronization pin, enable
Eliminate beat noise/ceramic caps/FPGA/regulation
from main power supply
TPS40200
TPS54317
DC/DC Converter
3.0 to 6.0VIN 3A DC/DC with integrated switch FET,
synchronization pin, enable
Eliminate beat noise/ceramic caps/FPGA/
integration
TPS54610/TPS54910
TPS54350
DC/DC Converter
4.5 to 20VIN 3A DC/DC with integrated switch FET,
synchronization pin, enable
Eliminate beat noise/ceramic caps/FPGA/
integration
TPS54550
TPS6206x
Step-Down
Converter
High frequency operation, 2x2 QFN package,power
save mode
High efficiency, small solution size
TPS62290
TPS62110
Step-Down
Converter
3.1V to 17V VIN, 1.5A conversion, synchronization pin,
Low battery indicator, power save mode
Very low noise/high efficiency
TPS62050
TPS62400
Dual Output
Step-Down
Converter
180° out of phase operation, serial interface
Flexible voltage adjustment for processors and
MCUs
TPS62420
TPS74201
Single-Channel
LDO
1.5A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat generation
TPS74301, TPS74801
TPS74401
Single-Channel
LDO
3.0A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat generation
TPS74901
TPS74701
Single-Channel
LDO
0.5A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat generation
UCD90120
12-Channel
Sequencer
GUI for programming 12 power rails
Sequencing, monitoring and margining
New products are listed in bold red.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
UCD9081, UCD90124
103
Texas Instruments 2010
Medical Imaging
➔ CT Scanners
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
RF ICs
RF Transceivers
CC1101
Sub-1GHz RF
Transceiver
Wake-on-radio functionality; integrated packet handling
with 64B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2-500kbps; extremely fast PLL turn-on/hop time
Ideal for low-power systems; any low-end MCU
can be used; backwards-compatible with existing
systems; suitable for fast frequency-hopping
systems
CC2500
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temperature
range; AES-128 security module
Reliable RF link with interference present; 400-m
line-of-sight range with the development kit; ideal
for industrial applications; no external processor
needed for secure communication
CC2530
RF Systems-on-Chip
CC2560
2.4GHz Bluetooth®
2.1 chipset
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
Sophisticated low-power technology ideal for
battery operated solutions
CC1110/11
Sub-1GHz
System-on-Chip
MCU, USB 2.0, flash and RAM in one package; four
flexible power modes for reduced power consumption;
includes CC1101 transceiver frequency synthesizer;
built-in AES-128 encryption coprocessor
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
CC2510, CC2511
CC2530/31
Second
Generation
System-on-Chip
Solution for
2.4GHz IEEE
802.15.4/RF4CE/
ZigBee
Excellent Rx sensitivity, low power, easy to use
development tools
RF design made easy for fast time to market;
provides a robust and complete ZigBee USB dongle
or firmware-upgradable network node
CC2590/91, CC2530ZNP,
CC2531
CC2540
2.4GHz
Bluetooth® Low
Energy compliant
RF System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity, selectivity
and blocking performance
A fast-to-market Bluetooth® low energy compliant
solution
Single-chip 802.11b/g/n WLAN and Bluetooth® solution
using TI’s digital radio processor technology using a
single antenna.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations; supports
ANT+ standard.
Sophisticated low-power technology ideal for
battery operated solutions; coexistence features
enable simultaneous WLAN and Bluetooth®
operations; supports ANT+ standard.
WL1271
WL1273
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
WL1273
WL1271
RF Network Processor
CC2530ZNP
Second
Generation
Z-Stack™
Network Processor
ZigBee® stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings
New products are listed in bold red. Preview products are listed in bold blue.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Add CC2530ZNP and your system is ZigBee
enabled; ideal for battery-operated excellent
selectivity and blocking performance systems;
excellent coexistence with Bluetooth® technology
and Wi-Fi.
104
Texas Instruments 2010
Medical Imaging
➔ Magnetic Resonance Imaging (MRI)
Magnetic Resonance Imaging (MRI)
Magnetic resonance imaging (MRI) is a non-invasive diagnostic technology
that produces physiologic images of
the human body. Powerful magnets
create a field that forces hydrogen
atoms in the body into a particular
alignment. Radio frequency (RF) energy
distributed throughout the body is
interrupted by body tissue. The disruptions correspond to varying
return signals which, when processed,
create the image.
Accurate signal processing is key to
obtaining high-quality images. A key
system consideration for the receive
channel is high SNR. The return signals
have narrow bandwidths, with an IF
location dependent on the main magnet’s strength. Some systems use high-speed pipeline ADCs with wideband amplifiers to sample the IF, leaving
large headroom for post-processing
gain by a digital down converter or
FPGA. Other systems mix the IF to
baseband where lower speed, higher
resolution SAR and delta-sigma ADCs
can be used.
High-resolution, high-speed DACs are
needed to control the magnetic and RF
energy in the MRI. High resolution is
required to accurately define the area
of the patient to be scanned and high
speed is needed to match the high IFs
generated by the main magnet.
DSPs can be used to provide gradient
processor control for properly controlling MRI system magnets. DSPs are
also useful for implementing signal
processing functionalities in MRI
devices. MRI reconstruction is based
mostly on 2-D Fourier transformation. In addition, functionalities like autoand cross-correlation, curve fitting,
combin­ing sub-images and motion
stabilization are required to pre- and
post-process the image to reduce
various artifacts.
Analog ICs and embedded processors
are playing a key role in improving the
delivery speed and crisp detail of
magnetic resonance images, leading to
more accurate diagnoses and effective
treatments. Accurate signal processing
is key to high-quality MRI images.
Product portfolio for MRIs
• Some systems use high-speed pipe line ADCs with wideband amplifiers
to sample the intermediate frequency
(IF) generated by the main magnet.
• Other systems mix the IF to base band, allowing for the use of lower
speed, higher resolution successive
approximation registers (SARs) and
delta-sigma ADCs.
• High-resolution DACs can control the
magnetic and RF energy in an MRI.
• DSPs like the TMS320C6452 can
provide gradient processor control
for properly controlling the magnets
and preprocess the signal before
it reaches the image reconstruction
engine.
• Other products for MRI systems and
equipment manufacturers include
operational amplifiers, clocking
distribution, interface and power
management devices.
Magnet
Gradient
Coil
TX/RX Coil
Pre
Amp
ADC
System
Power
Synthesizer
MRI Equipment
Gradient
Coil
Magnet
Processor
I/O
Power
Analog
Power
Surface Coil
TX/RX Coil
Core
Power
RF
Amp
Gradient
Power and
Control
RF
Modulator
DAC
DAC
Pulse Generation
and
Control/Timing
Clocking
Interface
LEGEND
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Magnetic resonance imaging (MRI) system block diagram.
Medical Applications Guide
105
Texas Instruments 2010
Medical Imaging
➔ Magnetic Resonance Imaging (MRI)
16-Bit, 10MSPS Delta-Sigma ADCs for Scientific Instrumentation
ADS1605, ADS1610
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/ADS1605 or
www.ti.com/sc/device/ADS1610
Key Features
• Output data rate: 10MSPS
(ADS1610), 5MSPS (ADS1605)
• Signal bandwidth: 4.9MHz
• SNR: 86dBFS
• THD: –94dBS
• SFDR: 95dB
• On-chip digital filter simplifies anti-alias requirements
• Low group delay: 3µs
• Parallel interface
• Direct connection to TMS320 DSPs
• Packaging: TQFP-64
The ADS1610 delta-sigma topology provides key system-level design advantages
with respect to anti-aliasing filtering and clock jitter. Output data is supplied over a
parallel interface and easily connects to TMS320™ DSPs. The power dissipation can
be adjusted with an external resistor, allowing for reduction at lower operating speeds.
AVDD
VREFP
VREFN
VMID
Applications
• Scientific
instruments
• Test equipment
• Communications
RBIAS
VCAP
DVDD
PD
Bias Circuits
SYNC
CLK
AINP
∆Σ
Modulator
AINN
Parallel
Interface
Digital
Filter
CS
2xMODE
RD
DRDY
OTR
ADS1610
DOUT[15:0]
AGND
DGND
ADS1610 functional block diagram.
12, 14-Bit, Single, Dual and Quad ADCs from 65 to 250MSPS
ADS64xx, ADS62xx, ADS62Pxx, ADS61xx, ADS61Bxx
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/ADS6424
DRVDD
DRGND
AVDD
•11, 12, 14-bit res. from 65 to 250MSPS
•Quad, dual and single versions
•Total power: 260 to 780mW per ch. •SNR: 70dBFS at FIN = 250MHz,
125MSPS
•SFDR: 81dBc at FIN = 250MHz, 125MSPS
•3.5dB coarse gain, up to 6dB programmable fine gain for SFDR/SNR trade-off
•Serialized (quads, duals) and parallel
(duals, singles) output options
•Programmable output terminations
and LVDS drive strength
•Analog and digital supply: 3.3V
The ADS6000 family features high-performance single and dual channel ADC solutions from 65 to 250MSPS and quad ADC solutions from 65 to 125MSPS, with
both parallel and serialized output options. The family is designed for demanding
wireless applications with high performance at high IFs — up to 70dB SNR with
81dBc SFDR at 250MHz. The ADS6000 family is extremely flexible with programmable gain settings, LVDS termination resistors and LVDS drive strength. Additionally, all family members with the same channel and output format are pin-forpin compatible, allowing for eased migrations between speeds and resolutions.
AGND
Key Features
LVDS Interface
DA0_P/M
DA2_P/M
INA_P
INA_M
Sample
and
Hold
14-Bit
ADC
Digital
and
DDR
Serializer
DA4_P/M
DA6_P/M
DA8_P/M
DA10_P/M
DA12_P/M
CLKP
CLKM
CLKOUTP/M
DB0_P/M
INB_P
INB_M
Sample
and
Hold
14-Bit
ADC
Digital
and
DDR
Serializer
DB2_P/M
DB4_P/M
DB6_P/M
DB8_P/M
DB10_P/M
VCM
Reference
Control Interface
DB12_P/M
SDOUT
Functional block diagram.
Medical Applications Guide
Output
Clock
Buffer
CLOCKGEN
106
RESET
SCLK
SEN
SDATA
CTRL1
CTRL2
CTRL3
Applications
•Software defined radios
• Multi-antenna receivers
• High IF receivers
•Wireless communications:
• DPD feedback loops
• Wideband digital repeaters
•High density general purpose digitizers
Texas Instruments 2010
Medical Imaging
➔ Magnetic Resonance Imaging (MRI)
Wideband Operational Transconductance Amplifier
OPA861
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/OPA861
• Wide bandwidth: 80MHz, open-loop, G = +5
• High slew rate: 900V/µs
• High transconductance: 95mA/V
• External IQ control
• Low quiescent current: 5.4mA
Applications
• Video equipment
• Communications
• High-speed data acquisition
• Wideband LED drivers
• Control-loop amplifiers
• Wideband active filters
• Line drivers
The OPA861 is a wideband, bipolar operational transconductance amplifier (OTA). The OTA or voltage-controlled current source can be viewed as an ideal transistor. Like a transistor, it has three terminals — a high-impedance input (base), a lowimpedance input/output (emitter) and the current output (collector). The OPA861,
however, is self-biased and bipolar. The output collector current is zero for a zero
base-emitter voltage. AC inputs centered about zero produce an output current,
which is bipolar and centered about zero. The transconductance of the OPA861
can be adjusted with an external resistor, allowing bandwidth, quiescent current
and gain trade-offs to be optimized.
0
R
C1
R
VIN
VOUT
C2
Low-pass negative impedance
converter (NIC) filter.
Gain (dB)
Key Features
–10
–20
–30
–40
–50
–60
–70
–80
10MHz
Low-Pass Filter
20kHz
Low-Pass Filter
1k
10k
100k
1M
10M
100M
1G
Frequency (Hz)
Frequency response of 20kHz and
10MHz low-pass NIC filters.
High-Performance Fixed-Point DSP
TMS320C6452
Get samples, datasheets, tools and application reports at: www.ti.com/sc/device/TMS320C6452
Key Features
• 720, 900MHz C64x+™ clock rate
• 1.39, 1.11ns instruction cycle time
• 5760, 7200MIPS
• Eight 32-bit C64x+ instructions/cycle
• Extensions to VelociTI™ advanced
very-long-instruction-word (VLIW)
TMS320C64x+™ DSP core
• C64x+ instruction set features
• C64x+ L1/L2 memory architecture
Applications
• MRI
• Imaging
• Telecom infrastructure
• Communications
TMS320C64x+ DSPs are the highest performance fixed-point DSP generation in the
TMS320C6000™ DSP platform. The C6452 device is based on the third-generation
high-performance, advanced VelociTI very-long-instruction-word (VLIW) architecture,
making these DSPs
Timers
an excellent choice
JTAG
(4 64-bit
PLL
or
8 32-bit)
for applications
PCI66
GPIO x32
or
including medical
UHPI
imaging, telecom
EDMA3.0
3-port Ethernet
SGMII
infrastructure and
Switch
CC
x2
Subsystem
TC
TC
TC
TC
communications. The C64x+ devices
VLYNQ
are upward-codeSwitched Central Resource
compatible from
DDR2
previous devices
EMIFA 16-bit
that are part of
McASP
L1D 32KB
L2 RAM
UART
the C6000™ DSP
1408KB
SPI
platform.
C64x+
2
I C
Mega
TSIP1
L1P 32KB
TSIP0
L2 ROM
64KB
TMS320C6452 functional block diagram.
Medical Applications Guide
107
Texas Instruments 2010
Medical Imaging
➔ Magnetic Resonance Imaging (MRI)
8-Channel, Ultra-Low-Power, 12- and 10-Bit, 50- to 65-MSPS
Analog-to-Digital Converters with Serialized LVDS Interface
ADS5281, ADS5282, ADS5287
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with ADS5281, ADS5282 or ADS5287)
Medical and other imaging:
• Ultrasound
• MRI
• PET
Clock
Buffer
LVDD
(1.8V )
Applications
AVDD
(3.3V )
The ADS5281 family also incorporates advanced features to optimize system performance, including programmable gain from 0 to 12dB in 1dB steps, 1/f
(flicker) noise suppression and 6dB input overload recovery within one clock cycle. Available with 12-bit resolution at 50 and 65MSPS and 10-bit resolution at 65MSPS, the ADS5281 family has the flexibility to offer the optimal solution for the entire spectrum of imaging systems.
(AVSS)
CLK N
• 8-channel 12- or 10-bit ADCs in one
small 64-pin QFN package
• ADS5281 also available in 80-pin
TQFP pin-compatible to ADS527x
• 77mW per channel at 65MSPS
64mW per channel at 50MSPS
• 70dB SNR for 12-bits at 10MHz IF
• 1/f (flicker) noise suppression
• Up to 6dB overload recovery in one
clock cycle
• Individual channel power down
• Direct interface with VCA8500
8-channel variable-gain amplifier
• Xilinx-supported deserializer code
The ADS5281 family provides eight high-performance ADCs in a small 64-pin QFN
package, making it possible to implement high channel counts in high-performance
ultrasound and other medical imaging systems. The low power dissipation per channel aids in making compact ultrasound equipment where space and battery life are at a premium, and in conjunction with the VCA8500 offers a
high-performance LNA-to-digital solution for less than 130mW per channel in ultrasound applications. (ADCLK)
CLK P
Key Features
PLL
6x ADCLK
LCLK P
12x ADCLK
LCLK N
1x ADCLK
ADCLK P
ADCLK N
IN1P
12-Bit
ADC
IN1N
Digital
OUT1P
Serializer
OUT1N
Channels
2 to 7
12-Bit
ADC
IN8N
Digital
Output
Format
Drive
Current
SDATA
CS
RESET
Registers
SCLK
REFT
REFB
VCM
ISET
INT/EXT
OUT8 N
Test
Patterns
Digital
Gain
(0 dB to
12 dB)
Reference
OUT8 P
Serializer
PowerDown
ADC
Control
PD
IN8P
ADS5281/2/7 functional diagram.
Medical Applications Guide
108
Texas Instruments 2010
Medical Imaging
➔ Magnetic Resonance Imaging (MRI)
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers
OPA861
*Page 107
PGA870
THS4503
Transconductance
Amp
Fully Differential
PGA
High-Speed Op Amp
80MHz, open loop, G = +5BW, 900V/µs SR
95mA/V high transconductance, 5.4mA IQ
THS9000
Cascadeable Amp
650MHz BW, gain range: -11.5dB to +20dB, OIP3
+47dBm at 100MHz
370MHz BW, 3700V/µs SR, 5V, ±5V, 12V and 15V
supply
50MHz to 400MHz, 50Ω input/output impedance
Optimized for low distortion, accomodates
varying signal levels
Low distortion, fully differential
ADS1605
*Page 106
16-bit, 10-MSPS
Delta-Sigma ADC
10 to 5MSPS, parallel interface with direct
connection to TMS320 DSPs
ADS1610
*Page 106
ADS5281
*Page 108
ADS5282/87
*Page 108
ADS5423
Delta-Sigma ADC
16-bit, 10MSPS, parallel interface
High-Speed ADC
8-channel, ultra-low-power, 12- and 10-bit, 50 to
65MSPS analog-to-digital converter
Ultra-low-power, 8-channel, 12-bit, 65MSPS
High-Speed ADC
ADS5545
High-Speed ADC
ADS5547
High-Speed ADC
ADS5562
High-Speed ADC
ADS61xx/61Bxx
*Page 106
ADS62xx/62Pxx
*Page 106
ADS64xx
*Page 106
ADS6425
High-Speed ADC
High-Speed ADC
DAC904
DAC5672
DAC5681Z
DAC5687
High-Speed DAC
High-Speed DAC
High-Speed DAC
High-Speed DAC
DAC7725
VOUT DAC
Quad, 12-bit, 250mW (max) power, 10µs to
0.012% settling time
REF02
Precision VREF
REF102
10 V, Ultra Precision
REF31xx
Voltage Reference
REF32xx
Low Drift, Bandgap
REF33xx
Very Low Power
Series Reference
REF5010
Low Noise, Very
Low Drift, Precision
Voltage Reference
High-Precision, Very
Low Drift Series
Reference
0.2% (max) initial accuracy, 10ppm/°C (max)
drift, 1.4mA (max)
0.05% (max) initial accuracy, 2.5ppm/°C (max)
drift, 1.4mA (max)
15ppm/°C (max) drift, 5mV low dropout, 115µA
(max) IQ, 0.2% (max) accuracy, 1.25V, 2.048V,
2.5V, 3.0V, 3.3V, 4.096V
0.2% (max) accuracy, 7ppm/°C (max) drift, 0.1mA
(max) IQ, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
5µA, 0.15% initial accuracy, 30ppm/°C max drift,
±5mA output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V,
3.3V
0.05% initial accuracy, 3ppm/°C max drift,
±10mA output, 10V
THS4504, THS4141
High dynamic range, single supply
Data Converters
High-Speed ADC
High-Speed ADC
High-Speed ADC
Provides key system-level design advantages
with respect to anti-aliasing filtering and clock
jitter.
SYNC pin for simultaneous sampling
14-bit, 80MSPS, 74dBc at 80MSPS and 50MHz
IF SNR
14-bit, 170MSPS, DDR LVDS/CMOS outputs
14-bit, 210MSPS, user-selectable DDR LVDS or
CMOS parallel outputs
Low-power, 16-bit ADC with up to 84dBFS SNR
11- /12- /14-bits, 65 to 250MSPS, 3.3V, 260 to
780mW per channel
11- /12- /14-bits, 65 to 250MSPS, 3.3V, 260 to
780mW per channel
11- /12- /14-bits, 65 to 250MSPS, 3.3V, 260 to
780mW per channel
4-channel, 12-bit, 125MSPS, serial LVDS
interface, 1.65W total power
14-bit, 165MSPS DAC
14-bit, 275MSPS dual DAC
16-bit, 1GSPS 2x-4x interpolating DAC
16-bit, 500MSPS interpolating with NCO
77mW per channel, serialized LVDS outputs, 1/F
noise-suppression
77mW per channel, serialized LVDS outputs, 1/f
noise suppression
3.3V CMOS-compatible outputs,
2s-complement output format
Programmable output clock position to ease
data capture
High performance
ADS1610
ADS1605
ADS5282, ADS5287
ADS5281, ADS5287
ADS5424, ADS5433
ADS5546, ADS5547
ADS5545, ADS5546
High SNR, 1/f noise suppression with low power
and small package ease data capture
High performance
ADS5560
ADS62xx, ADS62Pxx, ADS64xx
High performance
ADS61xx, ADS61Bxx, ADS64xx
High performance
ADS61xx, ADS61Bxx, ADS62xx,
ADS62Pxx
High performance, multiple input option
Low-power DAC
High sample rate with low power
High sample rate allows direct launch to low RF
Digital integration and superior AC performance
for flexible application and high-quality
transmission
Double-buffered data inputs
DAC5662, DAC5652
DAC5681, DAC5682Z
DAC5686
DAC7724, DAC902, DAC900
References
REF50xx
0.05% initial accuracy, 3ppm/°C max drift,
±10mA output, 2.048V, 2.5V, 3.0V, 4.096V,
4.5V, 5.0V
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Excellent line/load regulation, low noise
REF5050
Excellent stability and line/load regulation
REF5010
No load capacitor required
REF31xx, REF32xx, REF33xx
Multiple output voltages, SOT23-6
Preserves battery life, fits into physically
constrained systems
REF30xx, REF31xx, REF29xx
Improves system accuracy
REF102
Improves system accuracy
REF02
New products are listed in bold red.
109
Texas Instruments 2010
Medical Imaging
➔ Magnetic Resonance Imaging (MRI)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator,
video accelerators
Laptop-like performance at portable power
levels
OMAP3503, OMAP3515,
OMAP3525
TMS320C6452/55
*Page 107
DSP
900MHz, 1.4MB L2 cache, 2 x SGMII/Gigabit
EMAC
High-performance DSP with improved system
cost
TMS320C6414, TMS320C6455,
TMS320C6454, TMS320C6747
TMS320C6455BZTZ
DSP
1.2GHz, SRIO, 2MB RAM
High-performance, fixed-point 16-bit processor
TMS320C6454BZTZ
TMS320F2808
32-Bit MCU
100MIPS, 8KB ROM, 36KB RAM, 128KB flash,
12-bit ADC
I2C, 4 SPI, 2 SCI, 2 CAN
TMS320F28015
32-Bit MCU
60MIPS, 8KB ROM, 12KB RAM, 32KB flash,
12-bit ADC
I2C, 1 SPI, 1 SCI
TMS320F28234
32-Bit MCU
McBSP, 1 SPI, 2 SCI, 2 CAN
TMS320F283x
Delfino™
32-Bit Floating-point
Microcontroller
150MIPS, 8KB ROM, 68KB RAM, 256KB flash,
12-bit ADC
Up to 300MHz C28x™ core. Up to 512KB Flash,
high resolution (150ps) PWMs, 12MSPS ADC,
CAN/LIN, QEP, external memory bus, DMA.
TMS320C6474
DSP
3 x 1GHz C64x+ cores, 3MB RAM, SRIO
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point
brings increased performance and quicker
development. Ideal for precision sensing and
control applications.
High-performance multiprocessor solution
TMS320F2802x/3x Piccolo,
TMS320F280x
Interface
SN65MLVD128
1:8 Fanout Buffer
200Mbps
Standardized M-LVDS
SN65MLVD2
SN65LVDS93A
24-Bit RGB LVDS
Serdes
10MHz-135MHz, BGA and TSSOP; supports 1.8V
to 3.3V TTL i/p
Wide frequency range, save space, no level
shifter for 1.8V powered uP
SN75LVDS83B
CDCE62005
Clock Generator
rms jitter <1ps, recommended clocking solution
for AFE580x and ADS528x/527x
Integrated VCO saves system cost
CDCE72010, CDCM7005
CDCE(L)949
Clock Synthesizer
Recommended clocking solution for TI DSPs
0ppm multiple-frequency generation
CDCE(L)937, CDCE(L)925,
CDCE(L)913
CDCE906
Clock Synthesizer
Recommended clocking solution for TI DSPs
0ppm multiple-frequency generation
CDCE706
Clocking
Digital Up/Down Converters
GC5016
Digital Up/Down
Converter
Quad, 160MSPS for 4 channels, 115dB SFDR
Many multiplex output options
GC5018
Digital Down
Converter
8-channel, real or complex DDC inputs, 115dB
SFDR NCO
Final ACG
10A, 2.2V to 5.5V VIN, adjustable VOUT, with
TurboTrans™ Technology
16A, 4.5V to 14V VIN, adjustable VOUT, with
TurboTrans Technology
100W, 1500V DC isolation, differential remote
sense
Triple processor supervisor
Complete power supply designed to meet ultrafast transient requirements
Complete power supply designed to meet ultrafast transient requirements
High efficiency, industry-standard pincompatible
Two fixed and one adjustable supervisor for
system flexibility
High integration and high accuracy
Power Management
PTH04T240
Power Module
PTH08T220
Power Module
PTQA430033
Isolated DC/DC
Module
Voltage Supervisor
TPS3307
TPS386000
TPS40020
4-Channel
Supervisor
DC/DC Controller
2.25V to 5.5VIN, synchronization pin, enable
TPS40075
DC/DC Controller
4.5V to 28VIN, synchronization pin, enable
TPS54317
DC/DC Converter
TPS54350
DC/DC Converter
TPS6206x
Step-Down
Converter
Step-Down
Converter
Dual Output StepDown Converter
Single-Channel LDO
3.0V to 6.0VIN 3A DC/DC with integrated switch
FET, synchronization pin, enable
4.5V to 20VIN 3A DC/DC with integrated switch
FET, synchronization pin, enable
High frequency operation, 2x2 QFN
package,power save mode
3.1V to 17V VIN, 1.5A conversion, synchronization
pin, Low battery indicator, power save mode
180° out of phase operation, serial interface
TPS62110
TPS62400
TPS74201
0.25% acc, down to 0.4V, watchdog
1.5A ultra-low-dropout linear regulator
PTH08T221
PTQB425080
TPS3808
TPS3808
Eliminate beat noise/ceramic caps/FPGA/
regulation from main power supply
Eliminate beat noise/ceramic caps/FPGA/
regulation from main power supply
Eliminate beat noise/ceramic caps/FPGA/
integration
Eliminate beat noise/ceramic caps/FPGA/
integration
High efficiency, small solution size
TPS40042
TPS62290
Very low noise/high efficiency
TPS62050
Flexible voltage adjustment for processors and
MCUs
Split bias and supply pin minimize heat
generation
TPS62420
TPS40057
TPS54610/TPS54910
TPS54550
TPS74301, TPS74801
New products are listed in bold red.
additional product information see designated page number.
*For
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
PTH04T241
110
Texas Instruments 2010
Medical Imaging
➔ Magnetic Resonance Imaging (MRI)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
TPS74401
Single-Channel LDO
3.0A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat
generation
TPS74901
TPS74701
Single-Channel LDO
0.5A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat
generation
UCD90120
12-Channel
Sequencer
GUI for programming 12 power rails
Sequencing, monitoring and margining
UCD9081, UCD90124
CC1101
Sub-1GHz RF
Transceiver
2.4GHz ZigBee/
IEEE 802.15.4 RF
Transceiver
Ideal for low-power systems; any low-end MCU can be
used; backwards-compatible w/existing systems;
suitable for fast frequency-hopping systems
Reliable RF link w/interference; 400m line-of-sight
range with dev. kit; ideal for industrial apps; no external
processor needed for secure communication
CC2500
CC2520
Wake-on-radio functionality; integrated packet handling
w/64-B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2-500kbps; extremely fast PLL turn-on/hop time
Best-in-class coexistence and selectivity
properties; excellent link budget (103dBm);
extended temp range; AES-128 security module
MCU, USB 2.0, flash and RAM in one package;
four flexible power modes for reduced power
consumption; includes CC1101 transceiver
frequency synthesizer; built-in AES-128
encryption coprocessor
Excellent Rx sensitivity, low power, easy to use
development tools
Complete low-cost solution on single chip; ideal
for low-power battery-operated systems; robust
and secure link with good noise immunity;
no external processor needed for secure
communication; can connect directly to a PC
RF design System-on-Chip for quick time to
market; provides a robust and complete ZigBee
USB dongle or firmware upgradable network
node
A fast-to-market Bluetooth® low energy
compliant solution
CC2510, CC2511
Sophisticated low-power technology ideal for
battery operated solutions; coexistence features
enable simultaneous WLAN and Bluetooth®
operations; supports ANT+ standard.
WL1273
RF ICs
RF Transceivers
CC2530
RF Systems-on-Chip
CC1110/11
Sub-1GHz
System-on-Chip
CC2530/31
USB enabled Systemon-Chip solution for
2.4GHz IEEE 802.15.4/
RF4CE/ZigBee
2.4GHz Bluetooth®
Low Energy compliant
RF System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
CC2540
WL1271
Excellent link budget enabling long range
applications without external frontend, receiver
sensitivity, selectivity and blocking performance
Single-chip 802.11b/g/n WLAN and Bluetooth®
solution using TI’s Digital radio processor
technology using a single antenna.
CC2590/91, CC2530ZNP
RF Network Processor
CC2530ZNP
Second Generation
Z-Stack™ Network
Processor
ZigBee® stack and radio in one chip; implements
ZigBee certified stack; configurable device type
and network settings
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Add CC2530ZNP and your system is ZigBee
enabled; ideal for battery-operated excellent
selectivity/blocking performance systems; excellent
coexistence w/Bluetooth® technology and Wi-Fi.
New products are listed in bold red. Preview products are listed in bold blue.
111
Texas Instruments 2010
Medical Imaging
➔ Digital X-Ray
Digital X-rays – made possible
because of technologies like digital
signal processing – are revolutionizing
diagnostic radiology and spurring
innovative new applications, such
as their use in surgical procedures. A key benefit of digital X-rays is the
ability to store and transfer the digital
images, allowing for the outsourcing of
radiological services or easy access to
remote and/or specialized analysis.
A conventional X-ray system, regardless of whether its individual components are optimized, captures less than
40 percent of the original image information. By adding a digital detector to
digital X-ray imaging, it is possible to
capture more than 80 percent of the
original image information and use a
wide range of post-processing tools to
further improve the image. Other digital X-ray technology advances
made possible by semiconductor technology include:
• Faster diagnoses by eliminating photographic processing time and
facilitating quick transmission over
network connections. • Reduced costs by eliminating photographic processing film and
chemicals.
• Processing only the image data that highlights regions of interest,
suppressing irrelevant information.
• Combining image data with other
pertinent radiology information system (RIS) and hospital information
system (HIS) records.
• Archiving all relevant information
efficiently.
There are two different approaches to
digital X-ray technology: computed
Photo Detector and X-Ray Source
Motion Control
Temp Sense
Fan Control
The second approach, digital radiography, uses both direct and indirect
conversion. In direct conversion,
flat-panel selenium detectors absorb
X-rays directly and convert them into
individual pixel electric charges. In
indirect conversion, X-ray signals are
converted to light, and then converted
to electric charges. Both tiled chargecoupled device (CCD) arrays and computed tomography use indirect
conversion technology. Tiled CCD transitional technology employs multiple CCDs coupled to a scintillator
plate via fiber optics. Core and I/O
Power
LCD
Photo Detector
Array
Receive Path
Digital
Line
Drivers
AFE
ADC
Low
Level
Currents
X-ray
Source
radiology (CR) and digital radiography
(DR). Computed radiology involves
trapping electrons on an imaging plate
(IP) containing photo-stimulated-
phosphor (PSP) and exposing them to
generate image data. The IP is then
moved to a CR reader, where it is
scanned using a laser beam. DSP
Touch Screen
Control
And/Or
I to V
Backlight
FGPA
ASIC
REF
Low Noise Power
Interfaces to PC
Clock
RS232
802.11
Transmit
Tra
mit Path
Logic
Memory
Power
Plug
AC Line
AC/DC Supply
With Green Mode
Controller
Level Shift
FLASH/
EPROM
DAC
SDRAM
Bias
Control
LEGEND
System Power
Power Management
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Digital X-ray system block diagram.
Medical Applications Guide
112
Texas Instruments 2010
Medical Imaging
➔ Digital X-Ray
Computed tomography involves trapping electrons on photo-stimulated
plates and exposing them to generate
image data. In both approaches, charges
proportional to X-ray intensity seen by
the pixel are stored in the thin film transistor (TFT) storage cap. A number of
such pixels form the flat detector panel
(FDP). The charges are deciphered by
read-out electronics from the FDP and
transformed into digital data.
The block diagram shows the readout
electronics required for direct imaging
to convert the charge in the FDP to
digital data. It has two chains: the
acquisition and the biasing chain. At
the beginning of the acquisition chain,
an analog front-end is capable of multiplexing the charges on different FDP
(channels) storage caps and converting
those charges into voltage. The biasing
chain generates bias voltages for the
TFT array through interme­diate biasand-gate control circuitry. Digital control and data conditioning are controlled
by a DSP, an FPGA, an ASIC or a combination of these. These proc­es­sors
also manage high-speed serial communications with the external image
processing unit through a high-speed
interface (serialized, LVDS, optical).
Temperature sensors, DACs, amplifiers
and high-input voltage-capable switching regulators are other key system
blocks. Each block must have an
enable pin and synchronize frequencies
to avoid crosstalk with other blocks in
the acquisition chain. The number of
FDP pixels determines the number of
ADC channels versus ADC speed. Static or dynamic acquisition also
determines ADC speed. While static
acquisition means a single image in
less than 1 s, dynamic means an
image is refreshed at 30 Hz for more
specific cardiovascular, fluoroscopic or
related applications that require much
faster data conversion with the same
number of channels. An ADC in the
range of 2 MSPS or more with excellent DC performance will work well.
Medical Applications Guide
For indirect conversion, the CCD output
requires correlated double sampling
(CDS). The signal level’s reset voltages
and image signal level are converted to
digital data by an analog front end
(AFE). The AFE’s sampling speed is
determined by the number of pixels in
the CCD array and the frame rate. In
addition, the AFE corrects sensor
errors such as dark current correction,
offset voltages and defective pixels. Depending on the signal level, the
presence of programmable gain amplifiers (PGAs), the linearity of the PGAs
and the range of gains available may
also be important. During digitization,
the number of bits determines image
contrast. Typically, digitizing the initial
data with two to four bits more precision than desired in the final image is
recommended. For example, if 8 bits of
final image data are required, initially
digitize to 10 bits to allow for rounding
errors during image processing.
The main metric for image quality is
detection quantum efficiency (DQE),
a combination of contrast and SNR
expressed in percentage. The higher
the contrast and lower the noise, the higher the DQE. Contrast is the
number of shades of gray determined by the ADC’s output resolution. Generally, 14 or 16 bits are suitable for the application.
SNR indicates not only SNR from the
ADC, but system SNR impact from
X-ray dose, pixel size and all electronic
components. SNR can be improved by
increasing X-ray dose and photodiode
spacing and decreasing electronics
noise. Increasing the X-ray dose is
not suitable for patients or operators. Increasing photodiode spacing may
not be suitable because this decreases
spatial resolution. Decreasing the noise
from the system’s electronics is the
main challenge.
113
Total system noise is the root-squaresum of all noise contributions over the
signal chain, assuming all are uncorre­
lated. This means all parts have to be
ultra-low-noise or heavily filtered, when
applicable, including ADCs, op amps
and references. Stability over temperature is another important challenge. Internal temperature increases, due to
power dissipation, may offset gray
­levels and distort an image, especially
during dynamic acquisitions. Therefore,
temperature stability of ADCs, op
amps and references should be high.
The digital X-ray data undergoes several
processing steps before it is presented
to the display for viewing. The first
step, called shading, is where the nonidealities in the detector pixels are
corrected. Next, the unexposed area is
determined in the detector so that it is
not used in subsequent processing. Histogram equalization is then carried
out on the useful data. Finally, several
image enhancement techniques are
used for noise reduction, contrast
improvement and edge enhancement.
Product portfolio for digital X-rays
• High-performance DSPs for control
functions and signal conditioning to
acquire and improve the clarity of
the image. • Analog front ends (AFEs) capable of
multiplexing the charges on different
flat detector panels (FDPs), storage
caps (channels) and converting
these charges into voltage for direct
conversion X-rays. AFEs also convert the signal level and its reset
voltages to digital data and correct
sensor errors in indirect conversion
X-rays.
• Temperature sensors, DACs,
amplifiers and high-input voltage capable switching regulators are
other key system blocks.
• Power management and other
analog products.
Texas Instruments 2010
Medical Imaging
➔ Digital X-Ray
16-Bit, 4MSPS, Fully Differential Input ADC with Parallel Interface and Reference
ADS8422
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/ADS8422
Key Features
• Fully differential input with pseudobipolar input range: –4V to +4V
• 16-bit NMC at 4MSPS
• INL: 1LSB (typ)
• SNR: 92dB
• THD: –102dB (typ) with 100kHz input
• Internal 4.096V reference and reference buffer
• High-speed parallel interface
• Low power: 155mW at 4MHz (typ)
• Flexible power-down scheme
• REFIN /2 available for setting analog
input common-mode voltage
The ADS8422 is a 16-bit, 4MSPS ADC with internal 4.096V reference and a fully
differential, pseudo-bipolar input. It includes a full 16-bit interface and an 8-bit
option where data is read using two 8-bit read cycles if necessary. It is characterized over the industrial –40°C to +85°C temperature range.
+IN
BYTE
16-/8-bit
Parallel Data
Output Bus
CDAC
–IN
Comparator
1/
COMMOUT
2
REFIN
Applications
• Medical instruments
• Instrumentation
• Spectrum analysis
• High-speed, high-resolution, zerolatency data acquisition systems
Output
Latches
and
3-State
Drivers
SAR
Conversion
and
Control Logic
Clock
4.096-V
Internal Reference
REFOUT
PD2
RESET/PD1
CONVST
BUSY
CS
RD
ADS8422 functional block diagram.
High-Speed, Low-Noise, Fully Differential I/O Amplifiers
THS4130, THS4131
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/THS4130
or www.ti.comsc/device/THS4131
• Bandwidth: 150MHz (–3dB, VCC = ±15V)
• Slew rate: 51V/µs
• THD3 at 250kHz: –100dB
—–
• Low noise: 1.3nV/√Hz input referred
noise
• Differential input/differential output:
• Balanced outputs reject commonmode noise
• Reduced second harmonic distortion due to differential output
• Wide power supply range:
• Single supply: VCC = 5V
• Dual supply: ±15V
• Packaging: SOIC-8, MSOP-8,
MSOP-8 PowerPAD™ integrated
circuit package
Medical Applications Guide
The THS4130 and THS4131 are fully differential input/differential output amplifiers
with a true fully differential signal path from input to output. This design provides
excellent common-mode noise rejection and improved total harmonic distortion.
Typical A/D Application Circuit
Total Harmonic Distortion vs. Frequency
–20
VDD
–40
VOCM
VIN
VOUT = 2VPP
–30
5V
AIN
AVDD
DVDD
AIN AV
SS VREF
Digital
Output
THD (dB)
Key Features
–50
–60
VCC = 5V to ±5V
–70
–80
–90
–100
THS4130 application circuit.
VCC = ±15V
100k
1k
Frequency (Hz)
10k
Applications
• Single-ended to differential
conversion
• Differential ADC driver
114
• Differential antialiasing
• Output level shifter
• Differential transmitter and receiver
Texas Instruments 2010
Medical Imaging
➔ Digital X-Ray
Low-Noise, Very Low-Drift, High-Precision Voltage References
REF50xx
Get samples, datasheets and application reports at: www.ti.com/sc/device/REF5020
Key Features
• High accuracy: 0.05%
• Very low temperature drift: 3ppm/°C
• High output current: ±10mA
• Temperature range: –40°C to +125°C
• Packaging: MSOP-8, SO-8
Applications
• Medical instruments
• 16-bit data acquisition systems
• Industrial process control
• ATE equipment
The REF50xx is a family of low-noise, low-drift, high-precision voltage references. Designed for use in high-precision data acquisition systems, REF50xx has both
sinking and sourcing capability and is very robust to any line and load changes. The REF50xx has excellent temperature drift (3ppm/°C) and high accuracy both,
achieved by using a proprietary design technique and post-package precision
correction.
GNDs
1
8
NC
NC
1
8
NC
VIN
2
7
VOUTs
VIN
2
7
NC
Temp
3
6
VOUTf
Temp
3
6
GNDf
4
5
TRIM
GND
4
5
MSOP
SO-8
Model
Voltage Out
REF5020
2.048
REF5025
2.5
REF5030
3.0
VOUT
REF5040
4.096
TRIM
REF5045
4.5
Package diagrams.
REF5050
5
REF5010
10
TMS320C28x™ Controller Generation, Fixed-Point MCU Control, DSP Performance
TMS320F2810
Get samples, datasheets, tools and application reports at: www.ti.com/sc/device/TMS320F2810
• Ultra-fast 20 to 40ns service time to
any interrupts
• Powerful 20Mbps data logging
debugging capability
• 32-/64-bit saturation, single-cycle read-
modify-write instructions, and 64-/32bit and 32-/32-bit modulus division
• Enhanced tool suites with C and
C++ support
• Unique real-time debugging
capabilities
• 32-bit single-cycle fixed-point MAC
• Compatible with TMS320C24x™
DSPs and TMS320C2xLP source code
The TMS320F2810, TMS320F2811, TMS320F2812, TMS320C2810, TMS320C2811,
and TMS320C2812 ICs, members of the TMS320C28x DSP generation, are highly
integrated, high-performance solutions for demanding control applications. The
C28x™ controllers are 32-bit control-based DSPs with onboard reprogrammable
flash, factory-programmed ROM, or cost-effective RAM-only memory options and
perform­ance from 100 to 150MIPS.
Flash
Boot
ROM
RAM
QEP
Memory Bus
CAP
ADC
DMA
Interrupt Management
C28x™ 32-Bit Core
Peripherals
• 16 to 128Kword sectored flash or
factory-programmed ROM (with
code security)
• 12-bit ADC, as fast as 12.5MSPS
throughput with 80ns (min) conversion time
• Flexible QEP, CAP, timers and PWM
generation
• High-res mode resolution of 16-bits
at 100kHz and over 12-bits at
1.5MHz ePWM frequency
Medical Applications Guide
PWM
32 x 32-Bit
Multiplier
Pheripheral Bus
Key Features
GPIO
SPI
Atomic
ALU
SCI
I2 C
Timers
Real-Time
JTAG
EMIF
32-Bit
Floating-Point
Unit
CAN
McBSP
TMS320C28x digital signal controller block diagram.
• Up to two serial communication
interfaces (SCI/UART)
• Up to four serial peripheral interfaces
(SPI)
115
• Up to two enhanced CAN 2.0B
modules
• McBSP or I2C interface
Texas Instruments 2010
Medical Imaging
➔ Digital X-Ray
Component Recommendations
Component
Description
Amplifiers
Key Features
Benefits
OPA211
Precision Op Amp
OPA141
Precision Op Amp
—
1.1nV/√Hz at 1kHz noise, 3.6mA/ch supply, 80MHz BW
—
10MHz, 6.5nV/√Hz, ±4.5V to ±18V, 1.8mA typical, FET
input: IB = 20pA max
OPA277
Precision Op Amp
10µV offset, ±0.1µV/°C drift, 134dB open-loop gain
OPA827
Precision JFET Op
Amp
OPAx890
Other TI Solutions
Unity gain stable, RRO, shutdown
OPA227
Common mode voltage range includes GND
OPA827
4nV/√Hz noise at 1kHz, ±4V to ±18V supply, 15pA (typ)
input bias current, 22MHz BW
High precision, low noise, low input bias, wide
supply range
OPA177, OPA627,
OPA141
High-Speed Op Amp
Wide output swing of ±4.1 (Vs = ±5V)
Minimizes distortion when used as an ADC driver
THS403x
High-Speed Op Amp
—
100MHz, 1.6nV/√Hz noise, 100V/µs SR, 90mA output
OPA2890 (dual)
OPA2889 (dual)
Low distortion
THS4051, THS4081
THS413x
*Page 114
High-Speed Op Amp
150MHz (–3dB) BW, 51 V/µs SR, –100dB THD
at 250kHz
Differential input/differential output
THS4120, THS4150
THS4520
High-Speed Op Amp
Fully differential, RRO
Minimizes distortion when used as an ADC driver
ADS8413
SAR ADC
16-bit, 2MSPS, serial LVDS
LVDS, serial interface, daisy-chain capable
ADS8410, ADS8406
ADS8422
*Page 114
SAR ADC
16-bit, 4MSPS, int. ref and ref buffer
Zero latency
ADS8412, ADS8472
DAC8814
Multiplying DAC
16-bit, 0.5µs settling time, –105dB THD, 1 LSB (max)
relative ac-curacy
Double-buffered serial data interface
DAC7715, DAC8811
VSP2562
12-Bit, 36MSPS,
1-Channel Analog
Front End
Low noise, OB correct 2X 8b DAC, PGA amplifier
Better image quality; corrects for sensor dark
current offset; used for system tuning and
control of analog functions. Programmable gain
supports wide range of light conditions.
VSP2582
12-Bit, 36MSPS,
1-Channel Analog
Front End
Low noise, OB correct PGA amplifier
Better image quality; corrects for sensor dark
current offset. Programmable gain supports wide
range of light conditions.
SN65EL11
PECL/ECL 1:2
fanout Buffer
Differential 1:2 PECL/ECL fanout buffer
Maintains a known logic level when inputs are in
an open condition
SN65MLVD047
SN65ELT20
5 V TTL to
Differential PECL
Translator
1.25ns max prop delay
Built-in temperature compensation
SN65ELT21
SN65LV1023A
10:1 LVDS Serdes
Embedded clock
Smallest package
SN65LV1224B
SN65LVDS31
4-Channel LVDS
Driver
400Mbps
Industry standard
SN65LVDS32
TLK6201EA
PC Board Equalizer
Up to 6.25Gbps operation, low power, high-input
dynamic range
CML data outputs
1:2/4/8/12/16 or
Dual 1:2/4/6/8
Universal-to-LVPECL
Clock Buffers
Very low additive jitter <100ps RMS; 2.5V / 3.3V
operation
Improved clock signal quality by 10x; saves
additional interface logic / external components
CDCLVP111, CDCLVP215
TMP75
OPA4277 (quad)
Data Converters
Interface
Clocking
CDCLVP12xx/
21xx
Temperature Sensor
TMP175
Digital Temp Sensor
27 addresses, ±1.5°C (max) accuracy, 50µA IQ,
9- to 12-bit resolution
Two-wire interface, serial output
TMP275
Digital Temp Sensor
8 addresses, ±0.5°C (max) accuracy, 50µA IQ,
9- to 12-bit resolution
Two-wire interface, serial output
1W, 3kV isolation, minimal external components
Safety isolation, removal of ground loops,
reducing board space
Complete power supply designed to meet
ultra-fast transient requirements
Complete power supply designed to meet
ultra-fast transient requirements
Two fixed and one adjustable supervisor for
system flexibility
High integration and high accuracy
Power Management
DCH010505
PTH04T240
Galvanic Isolated
DC/DC Converters
Power Module
PTH08T220
Power Module
TPS3307
Voltage Supervisor
10A, 2.2V to 5.5V VIN, adjustable VOUT, with
TurboTrans™ Technology
16A, 4.5V to 14V VIN, adjustable VOUT, with TurboTrans
Technology
Triple processor supervisor
TPS386000
4-Ch. Supervisor
0.25% acc, down to 0.4V, watchdog
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
DCH010512, DCH010515
PTH04T241
PTH08T221
TPS3808
TPS3808
New products are listed in bold red.
116
Texas Instruments 2010
Medical Imaging
➔ Digital X-Ray
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
TPS40020
DC/DC Controller
2.25V to 5.5VIN, synchronization pin, enable
TPS40075
TPS54317
DC/DC Controller
DC/DC Converter
TPS54350
DC/DC Converter
TPS6206x
TPS62110
Step-Down Con.
DC/DC Converter
TPS62400
Dual Output StepDown Converter
Single-Channel LDO
Single-Channel LDO
Single-Channel LDO
12-Ch. Sequencer
4.5V to 28VIN, synchronization pin, enable
3.0V to 6.0VIN 3A DC/DC with integrated switch FET,
synchronization pin, enable
4.5V to 20VIN 3A DC/DC with integrated switch FET,
synchronization pin, enable
High frequency operation, 2x2 QFN pkg,power save mode
3.1 to 17VIN, 1.5A DC/DC w/integrated switch FET,
synchronization pin, enable, low battery indicator, PFM mode
180° out of phase operation, serial interface
Eliminate beat noise/ceramic caps/FPGA/
regulation from main power supply
Eliminate beat noise/ceramic caps/FPGA/regulation
Eliminate beat noise/ceramic caps/FPGA/
integration
Eliminate beat noise/ceramic caps/FPGA/
integration
High efficiency, small solution size
Very low noise/high efficiency
TPS40042
TPS40057
TPS54610/TPS54910
TPS54550
TPS62290
1.5A ultra-low-dropout linear regulator
3.0A ultra-low-dropout linear regulator
0.5A ultra-low-dropout linear regulator
GUI for programming 12 power rails
Flexible voltage adjustment for processors and
MCUs
Split bias and supply pin minimize heat generation
Split bias and supply pin minimize heat generation
Split bias and supply pin minimize heat generation
Sequencing, monitoring and margining
UCD9081, UCD90124
Applications Processor
Applications
Processor
DSP
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
1.2GHz, SRIO, 2MB RAM
High performance at handheld power levels
Laptop-like performance at handheld power
levels
High-performance, fixed-point 16-bit processor
AM3505
OMAP3503, OMAP3515,
OMAP3525
TMS320C6454BZTZ
DSP
DSP
DSP
6 x 700MHz C64x+ cores, 4.8MB RAM, SRIO, HPI
3 x 1GHz C64x+ cores, 3MB RAM, SRIO
150MIPS, controller area network (CAN) peripheral
DSP
C64x+™, ARM9, video accelerators
High-performance multiprocessor solution
High-performance multiprocessor solution
CAN for board-level communication, combination
of DSP performance and MCU integration
Image processing, display
CC1101
Sub-1GHz RF
Transceiver
CC2520
2.4GHz ZigBee/
IEEE 802.15.4 RF
Transceiver
Wake-on-radio functionality; integrated packet handling
w/64-B data FIFOs; high RF flexibility: FSK, MSK, OOK, 1.2500kbps; extremely fast PLL turn-on/hop time
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temp range;
AES-128 security module
Ideal for low-power systems; any low-end MCU can be
used; backwards-compatible w/existing systems;
suitable for fast frequency-hopping systems
Reliable RF link w/interference; 400m line-of-sight
range with dev. kit; ideal for industrial apps; no external
processor needed for secure communication
Complete low-cost solution on single chip; ideal
for low-power battery-operated systems; robust
and secure link with good noise immunity;
no external processor needed for secure
communication; can connect directly to a PC
RF design System-on-Chip for quick time to
market; provides a robust and complete ZigBee
USB dongle or firmware upgradable network
node
A fast-to-market Bluetooth® low energy
compliant solution
CC2510, CC2511
Single-chip 802.11b/g/n WLAN and Bluetooth® solution
using TI’s Digital radio processor technology using a
single antenna.
Sophisticated low-power technology ideal for
battery operated solutions; coexistence features
enable simultaneous WLAN and Bluetooth®
operations; supports ANT+ standard.
WL1273
ZigBee® stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings
Add CC2530ZNP and your system is ZigBee
enabled; ideal for battery-operated excellent
selectivity/blocking performance systems; excellent
coexistence w/Bluetooth® technology and Wi-Fi.
TPS74201
TPS74401
TPS74701
UCD90120
TPS62420
TPS74301, TPS74801
TPS74901
Processors
AM3517
OMAP3530
TMS320C6455BZTZ
TMS320C6472
TMS320C6474
TMS320F2810
*Page 115
TMS320DM6446BZWT
TMS320DM6441,
TMS320DM6437
RF ICs
RF Transceivers
CC2500
CC2530
RF Systems-on-Chip
CC1110/11
Sub-1GHz
System-on-Chip
MCU, USB 2.0, flash and RAM in one package; four
flexible power modes for reduced power consumption;
includes CC1101 transceiver frequency synthesizer;
built-in AES-128 encryption coprocessor
CC2530/31
USB enabled Systemon-Chip solution for
2.4GHz IEEE 802.15.4/
RF4CE/ZigBee
2.4GHz Bluetooth®
Low Energy
compliant RF Systemon-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
Excellent Rx sensitivity, low power, easy to use
development tools
CC2540
WL1271
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity, selectivity
and blocking performance
CC2590/91, CC2530ZNP
RF Network Processor
CC2530ZNP
Second Generation
Z-Stack™ Network
Processor
References
REF50xx
*Page 115
High-Precision,
Very-Low-Drift
Series Reference
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 2.048V, 2.5V, 3.0V, 4.096V, 4.5V, 5.0V, 10V
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Improves system accuracy
REF02
New products are listed in bold red. Preview products are listed in bold blue.
117
Texas Instruments 2010
Medical Imaging
➔ Positron Emission Tomography (PET) Scanners
Positron emission tomography (PET) is
a non-invasive diagnostic technology. Used to identify growing cancer cells,
for example, a PET scan uses radiation
emissions from the body (generated by
radioactive chemical elements consumed by the patient) to produce
physiologic images of specific organs
or tissues.
The radioactive emissions are converted
to light via a scintillation crystal detector and are amplified and converted to
an output current by a photomultiplier
tube (PMT). The PMT’s current output
is then converted to a voltage that is
amplified and filtered before being
converted to a digital signal by an ADC.
Signal proc­essing is needed for detector signal processing of the receive
channels and for a number of control
functions. DSPs, microcontrollers and
digital-to-analog converters are used in
this application for functions such as
varying input amplifier gain, controlling
the PMT high-voltage power supply,
and motion control for the detector
ring assembly and patient entry/exit.
like attenuation variations, detector
geometry and efficiency variations,
random and scatter coincidences, etc.
DSPs can be used for PET scanner
control and signal processing units. Filtered back-projection algorithms can
be used in image reconstruction. Several
iterative techniques have also been
proposed for PET image reconstruction. Additional signal pre-conditioning may
be necessary to correct various artifacts
Product portfolio for PET scanners
• Amplifiers, power management
products and other analog parts
are suitable for converting radio active emissions to light and
reconstruct and correct images.
• DSPs such as the TMS320C6455 can
handle tasks such as varying input
amplifier gain and controlling the
photomultiplier tube (PMT) high voltage power supply and motion
control for detector ring assembly
and patient entry/exit. DSPs are
also suitable for PET scanner control
and signal processing units.
Rx Gain Control
Interface
DAC
Radiation
PMT
Array
Amp
Amp
Coincidence
Processing
ADC
Timing and
Control
Rx Channels
Image
Processing
Motion Control
HV Supply
Control
DAC
DAC
Amp
Motor/Driver
Control
Power Management
Analog
Power
Digital
Power
Voltage
Reference
Power
Supervisor
Clock Source
Current Monitor
Temp Sensor
LEGEND
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
PET scanner system block diagram.
Medical Applications Guide
118
Texas Instruments 2010
Medical Imaging
➔ Positron Emission Tomography (PET) Scanners
8-Channel, Ultra-Low-Power, 12- and 10-Bit, 50 to 65MSPS
Analog-to-Digital Converters with Serialized LVDS Interface
ADS5281, ADS5282, ADS5287
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with ADS5281, ADS5282 or ADS5287)
LVDD
(1.8V)
AVDD
(3.3V )
The ADS5281 family also incorporates advanced features to optimize system performance, including programmable gain from 0 to 12dB in 1dB steps, 1/f (flicker)
noise suppression and 6dB input overload recovery within one clock cycle. Available with 12-bit resolution at 50 and 65MSPS and 10-bit resolution at 65MSPS, the ADS5281 family has the flexibility to offer an optimal solution for
the entire spectrum of imaging systems.
(AVSS)
CLK N
• 8-channel 12- or 10-bit ADCs in one
small 64-pin QFN package
• ADS5281 also available in 80-pin
TQFP pin-compatible to ADS527x
• 77mW per channel at 65MSPS; 64mW per channel at 50MSPS
• 70dB SNR for 12-bits at 10MHz IF
• 1/f (flicker) noise suppression
• Up to 6dB overload recovery in one
clock cycle
• Individual channel power down
• Direct interface with VCA8500
8-channel variable-gain amplifier
• Xilinx-supported deserializer code
The ADS5281 family provides eight high-performance ADCs in a small 64-pin QFN
package, making it possible to implement high channel counts in high-performance
ultrasound and other medical imaging systems. The low power dissipation per channel aids in making compact ultrasound equipment where space and battery life are at a premium, and in conjunction with the VCA8500 offers a high-performance LNA-to-digital solution for less than 130mW per channel in ultrasound applications. (ADCLK)
CLK P
Key Features
Applications
• Medical and other imaging:
• Ultrasound
• MRI
• PET
Clock
Buffer
PLL
6x ADCLK
LCLK P
12x ADCLK
LCLK N
1x ADCLK
ADCLK P
ADCLK N
IN1P
12-Bit
ADC
IN1N
Digital
OUT1P
Serializer
OUT1N
Channels
2 to 7
12-Bit
ADC
IN8N
Digital
Output
Format
Drive
Current
SCLK
Registers
SDATA
CS
RESET
REFT
REFB
VCM
ISET
INT/EXT
OUT8 N
Test
Patterns
Digital
Gain
(0 dB to
12 dB)
Reference
OUT8 P
Serializer
PowerDown
ADC
Control
PD
IN8P
ADS5281/2/7 functional diagram.
Medical Applications Guide
119
Texas Instruments 2010
Medical Imaging
➔ Positron Emission Tomography (PET) Scanners
Wideband, >40dB Gain Adjust Range Variable-Gain Amplifier
VCA821
Get samples, datasheets and evaluation modules at: www.ti.com/sc/device/VCA821
Key Features
• >40dB gain adjust range
• High gain accuracy: 20dB ±0.4dB
• Small signal bandwidth (G = +2): 710MHz (VCA821/824), 150MHz
(VCA820/822)
• Slew rate: 2500V/µs (VCA821/824),
1700V/µs (VCA820/822)
• Output current: ±160mA
(VCA820/822), ±90mA (VCA821/824)
—–
• Voltage noise: 8.2nV/√Hz
—–
(VCA820/822), 6nV/√Hz
(VCA821/824)
• Packaging: MSOP-10, SO-14
The VCA821 is a DC-coupled, wideband, variable-gain amplifier with linear gain
adjustment control for >40dB gain range. This amplifier provides a differential input to single-ended conversion with a high-impedance gain-control input used to vary the gain with linear in dB gain adjust. The output voltage of ±3.9V and current capability of ±90mA helps drive a large variety of loads. Also available from
this variable-gain family are the VCA820, offering linear in dB gain adjust, and the
VCA822 and VCA824, offering linear in V/V gain adjust.
VCA821
VIN
50Ω
+VIN
RG+ FB
200Ω
Medical Applications Guide
OPA695
50Ω
Out
RG –
–VIN
50Ω
VOUT
VG
50Ω
950Ω
Applications
• AGC receivers with RSSI
(VCA820/821)
• Pulse amplitude compensation
• Differential line receivers
• Differential equalizers (VCA822/824)
• Voltage-tunable active filters
• Variable attenuators
1kΩ
100Ω
50Ω
0.1µF
1kΩ
1N4150
VREF
OPA820
Variable-gain amplifier with AGC loop.
120
Texas Instruments 2010
Medical Imaging
➔ Positron Emission Tomography (PET) Scanners
Component Recommendations
Component
Description
Amplifiers
Key Features
Benefits
Other TI Solutions
OPA657
High-Speed Op Amp
—
FET-Input, 1.6GHz GBW, 4.8nV/√Hz noise, 70mA
output
High dynamic range, fast overdrive recovery
OPA860
Transconductance
Amp
80MHz, open loop, G = +5 BW, 900V/µs SR
95mA/V high transconductance, buffer
OPA827
Precision JFET Op
Amp
OPA211
Precision Op Amp
OPA2690
VFB Op Amp
THS4130
High-Speed Op Amp
THS7530
High-Speed VGA
VCA810
Voltage-Controlled
Amp
VCA821
*Page 120
Voltage-Controlled
Amp
>40dB gain adjust range with high gain accuracy
Adds flexibility and accuracy to design
VCA820
ADS5240
High-Speed ADC
4-channel, 12-bit, 40MSPS, serial LVDS interface
Integrated frame and bit pattern, 4 current modes
for LVDS
ADS5242, ADS5525
ADS5272
High-Speed ADC
8-channel, 12-bit, 65MSPS, 3.3-V analog/digital
supply
Serialized LVDS outputs, integrated frame and bit
patterns
ADS5281
*Page 119
High-Speed ADC
8-channel, ultra-low-power, 12- and 10-bit, 50 to
65MSPS analog-to-digital converter
77mW per channel, serialized LVDS outputs, 1/F
noise-suppression
ADS5282, ADS5287
ADS5282
*Page 119
High-Speed ADC
Ultra-low-power, 8-channel, 12-bit, 65MSPS
77mW per channel, serialized LVDS outputs, 1/f
noise suppression
ADS5281, ADS5287
ADS5287
*Page 119
High-Speed ADC
Ultra-low-power, 8-channel, 10-bit, 65MSPS
77mW per channel, serialized LVDS outputs, 1/f
noise suppression
ADS5281, ADS5282
ADS5525
High-Speed ADC
12-bit, 170MSPS, DDR/LVDS CMOS outputs
Programmable gain up to 6dB for SNR/SFDR
trade-off at high IF
ADS5527, ADS5545
ADS5527
High-Speed ADC
12-bit, 210MSPS, DDR/LVDS CMOS outputs
Internal/external reference support
ADS5545, ADS5440
ADS5562
High-Speed ADC
Low-power, 16-bit ADC with up to 84dBFS SNR
High SNR, 1/f noise suppression with low power
and small package
ADS5560
DAC2900
High-Speed DAC
10-bit, 125MSPS dual DAC
Supports 3.3/5V
DAC2902, DAC2904
DAC5652
High-Speed DAC
10-bit, 275MSPS dual DAC
High sample rate with low power
DAC5662, DAC5672
DAC7554
VOUT DAC
Quad, 12-bit, 2.7V to 5.5V supply, 5µs settling time
Ultra-low glitch, ultra-low crosstalk
DAC7614, DAC7615
DAC7731
VOUT DAC
16-bit, 150mW (max) low power, 5µs settling time,
+10V int. reference
Unipolar or bipolar operation
DAC8811
REF02
Precision VREF
0.2% (max) initial accuracy, 10ppm/°C (max) drift,
1.4mA (max)
Excellent line/load regulation, low noise
REF5050
REF102
10V, Ultra Precision
0.05% (max) initial accuracy, 2.5ppm/°C (max)
drift, 1.4mA (max)
Excellent stability and line/load regulation
REF5010
REF31xx
Voltage Reference
15-ppm/°C (max) drift, 5mV low dropout, 115µA
(max) IQ, 0.2% (max) accuracy, 1.25V, 2.048V, 2.5V,
3.0V, 3.3V, 4.096V
No load capacitor required
REF3130, REF3120
REF32xx
Low Drift, Bandgap
0.2% (max) accuracy, 7ppm/°C (max) drift, 0.1mA
(max) IQ, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
Multiple output voltages, SOT23-6
—
4nV/√Hz noise at 1kHz, ±4V to ±18V supply, 15pA
(typ) input bias current, 22MHz BW
—
1.1nV/√Hz noise at 1kHz, ±2.25V to ±18V supply,
80MHz BW
High precision, low noise, low input bias, wide
supply range
OPA141, OPA177,
OPA627
Unity gain stable, RRO, wide supply range
OPA227
Dual, 220MHz, G = 2 BW, 1800V/µs SR, 190mA
output
+5V supply, disable
OPA2691
150MHz BW (–3dB), 51V/µs slew rate, –100dB THD
at 250kHz
—
1.1nV/√Hz noise, 300MHz BW, 11.6dB to 46.5dB
continuously variable gain
—
±40dB high gain adjust range, 2.4nV/√Hz noise,
±60mA output current
High-speed, fully differential I/O
High-speed, fully differential
Differential in/single-ended out
Data Converters
References
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
121
Texas Instruments 2010
Medical Imaging
➔ Positron Emission Tomography (PET) Scanners
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
References (continued)
REF33xx
Very-Low-Power
Series Reference
5µA, 0.15% initial accuracy, 30ppm/°C max drift,
±5mA output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V, 3.3V
Preserves battery life, fits into physically
constrained systems
REF30xx, REF31xx,
REF29xx
REF5010
10V, High-Precision,
Very-Low-Drift Series
Reference
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 10V
Improves system accuracy
REF102
REF50xx
High-Precision,
Very-Low-Drift Series
Reference
0.05% initial accuracy, 3ppm/°C max drift,
±10mA output, 2.048V, 2.5V, 3.0V, 4.096V,
4.5V, 5.0V
Improves system accuracy
REF02
SN65EL11
PECL/ECL 1:2 Fanout
Buffer
Differential 1:2 PECL/ECL fanout buffer
Maintains a known logic level when inputs are in
an open condition
SN65MLVD047
SN65LVCP40
Dual 1:2 Mux/Buffer
Input EQ, output pre-emp
Improves signal range
SN65LVCP404
SN65LVDS93A
24-Bit RGB LVDS
Serdes
10MHz-135MHz, BGA and TSSOP; supports 1.8V to
3.3V TTL i/p
Wide frequency range, saves space, no level shifter
for 1.8V powered uP
SN75LVDS83B
TLK1221
Gigabit Ethernet
Serdes
Power 250mW
Smallest package
TLK2208B
CDCE62005
Clock Generator
rms jitter <1ps, recommended clocking solution for
AFE580x and ADS528x/527x
Integrated VCO saves system cost
CDCE72010, CDCM7005
CDCE(L)949
Clock Synthesizer
Recommended clocking solution for TI DSPs
0ppm multiple-frequency generation
CDCE(L)937,
CDCE(L)925, CDCE(L)913
CDCE906
Clock Synthesizer
Recommended clocking solution for TI DSPs
0ppm multiple-frequency generation
CDCE706
CDCLVP12xx/
21xx
1:2/4/8/12/16 or Dual
1:2/4/6/8 Universalto-LVPECL Clock
Buffers
Very low additive jitter <100ps RMS; 2.5V/3.3V
operation
Improved clock signal quality by 10x; saves
additional interface logic / external components
CDCLVP111, CDCLVP215
Interface
Clocking
Power Management
PTH04T240
Power Module
10A, 2.2V to 5.5V VIN, adjustable VOUT, with
TurboTrans™ Technology
Complete power supply designed to meet ultra-fast
transient requirements
PTH04T241
PTH08T220
*Page 125
Power Module
16A, 4.5V to 14V VIN, adjustable VOUT, with
TurboTrans Technology
Complete power supply designed to meet ultra-fast
transient requirements
PTH08T221
PTQA430033
*Page 125
Isolated DC/DC
Module
100W, 1500VDC isolation, differential remote sense
High efficiency, industry-standard pin-compatible
PTQB425080
TPS3307
Voltage Supervisor
Triple processor supervisor
Two fixed and one adjustable supervisor for system
flexibility
TPS3808
TPS386000
4-Channel Supervisor
0.25% acc, down to 0.4V, watchdog
High integration and high accuracy
TPS3808
TPS40020
DC/DC Controller
2.25 to 5.5VIN, synchronization pin, enable
Eliminate beat noise/ceramic caps/FPGA/regulation
from main power supply
TPS40042
TPS40075
DC/DC Controller
4.5 to 28VIN, synchronization pin, enable
Eliminate beat noise/ceramic caps/FPGA/regulation
from main power supply
TPS40057
TPS54317
DC/DC Converter
3.0 to 6.0VIN 3A DC/DC with integrated switch FET,
synchronization pin, enable
Eliminate beat noise/ceramic caps/FPGA/
integration
TPS54610/TPS54910
TPS54350
DC/DC Converter
4.5 to 20VIN 3A DC/DC with integrated switch FET,
synchronization pin, enable
Eliminate beat noise/ceramic caps/FPGA/
integration
TPS54550
TPS6206x
Step-Down Converter
High frequency operation, 2x2 QFN package,power
save mode
High efficiency, small solution size
TPS62290
TPS62110
DC/DC Converter
3.1 to 17VIN, 1.5A DC/DC with integrated switch
FET, synchronization pin, enable, Low battery
indicator, PFM mode
Very low noise/high efficiency
TPS62400
Dual Output StepDown Converter
180° out of phase operation, serial interface
Flexible voltage adjustment for processors and
MCUs
TPS62420
TPS74201
Single-Channel LDO
1.5A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat generation
TPS74301, TPS74801
TPS74401
Single-Channel LDO
3.0A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat generation
TPS74901
TPS74701
Single-Channel LDO
0.5A ultra-low-dropout linear regulator
Split bias and supply pin minimize heat generation
UCD90120
12-Channel
Sequencer
GUI for programming 12 power rails
Sequencing, monitoring and margining
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
UCD9081, UCD90124
New products are listed in bold red.
122
Texas Instruments 2010
Medical Imaging
➔ Positron Emission Tomography (PET) Scanners
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
TMS320C6452
DSP
900MHz, 1.4MB L2 cache, 2 x S GMII/Gigabit EMAC
High-performance DSP with improved system cost
TMS320C6455BZTZ
DSP
1.2GHz, SRIO, 2MB RAM
High-performance, fixed-point 16-bit processor
TMS320C6472
DSP
6 x 700Mhz C64x+™ cores, 4.8MB RAM, SRIO, HPI
High-performance multiprocessor solution
TMS320C6474
DSP
3 x 1GHz C64x+ cores, 3MB RAM, SRIO
High-performance multiprocessor solution
CC1101
Sub-1GHz RF
Transceiver
2.4GHz ZigBee/
IEEE 802.15.4 RF
Transceiver
Ideal for low-power systems; any low-end MCU can be
used; backwards-compatible w/existing systems;
suitable for fast frequency-hopping systems
Reliable RF link w/interference; 400m line-of-sight
range with dev. kit; ideal for industrial apps; no external
processor needed for secure communication
CC2500
CC2520
Wake-on-radio functionality; integrated packet handling
w/64-B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2-500kbps; extremely fast PLL turn-on/hop time
Best-in-class coexistence and selectivity
properties; excellent link budget (103dBm);
extended temp range; AES-128 security module
MCU, USB 2.0, flash and RAM in one package;
four flexible power modes for reduced power
consumption; includes CC1101 transceiver
frequency synthesizer; built-in AES-128 encryption
coprocessor
Excellent Rx sensitivity, low power, easy to use
development tools
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
RF design System-on-Chip for quick time to
market; provides a robust and complete ZigBee
USB dongle or firmware upgradable network node
CC2510, CC2511
Excellent link budget enabling long range
applications without external frontend, receiver
sensitivity, selectivity and blocking performance
Single-chip 802.11b/g/n WLAN and Bluetooth®
solution using TI’s Digital radio processor
technology using a single antenna.
A fast-to-market Bluetooth® low energy compliant
solution
TMS320C6454BZTZ
RF ICs
RF Transceivers
CC2530
RF Systems-on-Chip
CC1110/11
Sub-1GHz
System-on-Chip
CC2530/31
USB enabled System-onChip solution for 2.4GHz
IEEE 802.15.4/ RF4CE/
ZigBee
2.4GHz Bluetooth®
Low Energy compliant
RF System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
CC2540
WL1271
Sophisticated low-power technology ideal for
battery operated solutions; coexistence features
enable simultaneous WLAN and Bluetooth®
operations; supports ANT+ standard.
CC2590/91, CC2530ZNP
WL1273
RF Network Processor
CC2530ZNP
Second Generation
Z-Stack™
Network Processor
ZigBee® stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Add CC2530ZNP and your system is ZigBee
enabled; ideal for battery-operated excellent
selectivity/blocking performance systems; excellent
coexistence w/Bluetooth® technology and Wi-Fi.
New products are listed in bold red. Preview products are listed in bold blue.
123
Texas Instruments 2010
Medical Imaging
➔ Power Management for Medical Imaging
8-Channel Power-Supply Sequencer and Monitor
UCD9080
Get samples, datasheets, evaluation modules, application reports and software tools at: www.ti.com/sc/device/UCD9080
• I2C interface for configuration and
monitoring
• Microsoft Windows GUI for configuration and monitoring
• Flexible rail shutdown
• Supply voltage: 3.3V
• Low power consumption: 300µA, 3.0V
Key Features
• Sequencing and monitoring of up to
eight voltage rails
• All rails monitored and updated
every 50µs 3.5mV resolution
• Sequencing of up to three digital
outputs for power-on-reset and other
functions
• Under- and overvoltage threshold
per rail
Component
• Telecommunications switch servers
• Networking equipment
• Test equipment
• Any system requiring sequencing of
multiple voltage rails
Description
UCD9111
Single-phase POL digital power controller
UCD9112
Dual-phase POL digital power controller
UCD9501
32-bit digital signal controller for power management
UCD7100
Digital control, single low-side ±4-A MOSFET driver with
current sense
UCD7201
Digital control, dual low-side ±4-A MOSFET driver with
single common current sense
UCD7230
Digital power-compatible synchronous buck driver
POL-3
POL-4
Low
Dropout
Regulator
DC/DC
Converter
Low
Dropout
Regulator
DC/DC
Converter
RAIL3
POL-2
RAIL2
POL-1
RAIL1
RAIL0
Applications
3.3V
DC/DC
Converter
POL-5
Hard Drive
RAIL4
RAIL0
RAIL1
RAIL2
RAIL3
RAIL4
RAIL5
RAIL6
RAIL7
0
1
2
3
4
5
To
System
UCD9080
6
7
VDD_IPM
10kΩ
Enable
Outputs
A/D Inputs
0
1
2
3
4
5
EN0
EN1
EN2
EN3
EN4
EN5
6
7
EN6
EN7
10kΩ
SDA
SCL
????
Interface
VDD
Interrupt
Output
INT
INT
1.8V
Low
Dropout
Regulator
DSP
POL-6
DSP/µC
RAIL5
To
System
1.5V
Low
Dropout
Regulator
POL-7
Memory
RAIL6
VDD_IPM
5.0V
DC/DC
Converter
Interface
POL-8
RAIL7
UCD9080 functional block diagram.
Medical Applications Guide
124
Texas Instruments 2010
Medical Imaging
➔ Power Management for Medical Imaging
Second-Generation PTH Point-of-Load Modules
PTH08T2xx
Get samples, datasheets, evaluation modules, application reports and software tools at: www.ti.com/sc/device/PTH08T210W
Key Features
Benefits
T2s reduce development costs and
save PCB space:
• Sequencing easily solved with Auto-Track technology
• SmartSync synchronization for input
cap reduction/easier filtering
• TurboTrans™ technology
• 1.5% output regulation
• SmartSync synchronization
• Auto-Track™ sequencing
• TurboTrans technology for high
transient load applications
• Stable with ultra-low ESR caps
• 1.5% tolerance meets specs of
FPGA core
Typical Component Specifications
VIN
(V)
VOUT
(V)
IOUT
(A)
PTH04T260W
2.2 to 5.5
0.7 to 3.6
3
PTH08T260/261W
4.5 to 14
0.7 to 5.5
3
PTH04T230W
2.2 to 5.5
0.7 to 3.6
6
PTH08T230/231W
4.5 to 14
0.7 to 5.5
6
PTH04T240/241W
2.2 to 5.5
0.7 to 3.6
10
PTH08T240/241W
4.5 to 14
0.7 to 5.5
10
PTH04T220W
2.2 to 5.5
0.7 to 3.6
16
PTH08T220/221W
4.5 to 14
0.7 to 5.5
16
PTH05T210W
2.2 to 5.5
0.7 to 3.6
30
PTH08T210W
4.5 to 14
0.7 to 3.6
30
PTH08T250W
4.5 to 14
0.7 to 3.6
50
PTV08T250W
8 to 14
0.8 to 3.6
50
Model
SmartSync
Track
TurboTrans™ Technology
VI
2
10
1
Track SYNC
9
TT
VI
+Sense
PTH08T241W
Inhibit
11
RUVLO
1%
0.05Ω
(Optional)
INH/UVLO
GND
C1
200µF
(Required)
3
VO
–Sense
GND VOADJ
4
8
RTT
1%
0.05Ω
(Optional)
6
+ Sense
VO
5
7
C0
300µF
(Required)
RSET[A]
1%
0.05Ω
(Required)
GND
L
O
A
D
– Sense
GND
PTH08T2xx functional block diagram.
100W, Isolated DC/DC Module
PTQA430033
Get samples, datasheets, evaluation modules, application reports and software tools at: www.ti.com/sc/device/PTQA430033
Key Features
• 48V input (36V to 75V range)
• Standard quarter-brick footprint
• High efficiency (92 percent at 3.3V
full load)
• 1500V DC I/O isolation
Benefits
• On/off control
• Overcurrent protection
• Differential remote sense
• Undervoltage lockout
• Output overvoltage protection
• Overtemperature shutdown
• Pin-compatible with industry-
standard products
• Small size, high current applications
Sense (+)
+VO
7
Sense (+)
Typical Component Specifications
Model
PTQA
Input
(V)
Output
Current (A)
Output
(V)
4
30
025
4 = 48
30 = 30
025 = 2.5
20 = 20
033 = 3.3
+VI
1
+
–VI
CI
(Optional)
+VI
PTQA430xxxN
Adjust
3
–VI
–VO
Remote
On/Off
050 = 5.0
+VO
2
8
6
+
CO
(Optional)
4
–VO
Sense (–)
5
Sense (–)
PTQA430033 functional block diagram.
Medical Applications Guide
125
Texas Instruments 2010
Medical Imaging
➔ Medical Imaging Toolkit
TI Embedded Processor Software Toolkit for Medical Imaging (STK-MED)
Get more information at: www.ti.com/medicaltoolkit
View the “Ultrasound Scan Conversion Demo on OMAP3530” video at: www.ti.com/stkvideo
Key Features
• Common medical imaging algorithms optimized for the C64x+TM
DSP architecture
• Standard APIs
• Tested, benchmarked, documented
library modules
Applications
• Medical imaging
• Medical diagnostic ultrasound
• Optical Coherence Tomography (OCT)
Demos/Open source site
www.ti.com/ultrasounddemo
• Demo of scan conversion module running on OMAP3530
• Open Source of OMAP3530 demo’s
software framework
Medical Applications Guide
The STK-MED is a collection of several standard medical imaging algorithms optimized for TI’s C64x+ DSP architecture. The algorithms showcase how developers can leverage the C64x+ DSP architecture for efficient performance and power consumption in real-time medical imaging applications such as diagnostic ultrasound and optical coherence tomography (OCT). The goal of the STKMED is to shorten customer development time by providing highly optimized
C64x+ DSP source code of common ultrasound processing blocks.
Medical imaging processing
functions in STK-MED
• B-Mode processing
Doppler processing (color flow,
power estimator, wall filter)
• RF demodulation and decimation
• DAS beamforming
• Scan conversion
• Optimized math utilities
3D rendering
Real-time imaging processing for
optical coherence tomography (OCT)
126
Texas Instruments 2010
Medical Instruments
➔ Overview
Medical instruments are used in a wide range of caregiver laboratory and clinical applications. Some typical
applications include:
• Analytical instrumentation, ultrasonic
devices, spectrophotometers,
• Endoscopes and smart pills,
• Surgical instrumentation, surgical
power tools, robots and cameras,
• Laboratory instruments, in-vitro diagnostic equipment (for outsidethe-body analysis), blood gas analysis, labs on a chip, flow cytometry, microfluidic analysis,
• Robotics prosthetics,
• Therapeutics/hospital beds and
power wheel chairs,
• Dental equipment, GaAIAs lasers,
ultrasonic scalers, autoclaves. These applications are very specific in
design, consuming a wide variety of
sensor, actuation or receiving mechanisms. Most medical instruments share
general common system blocks and
needs. Examples include the need for
high-precision circuits to support the
precise acquisition of pressure, light
and temperature values and the need to leverage ultra-low-power processing to conserve battery life. This includes the acquisition of small
capacitance, changes in capacitance
and currents, or changes in voltages or
impedances.
TI’s portfolio provides several integrated
circuit (IC) solutions for these applications. Our precision linear portfolio
meets the need for typical ICs by
offering low-bias amplifiers (both
precision and high-speed) with
J-FET inputs, zero-drift operational
amplifiers for precision-over-lifetime
applications and low-noise amplifiers
for sensitive measurement circuits. Medical Applications Guide
Our data acquisition portfolio complements these components by offering
high-resolution, low-noise, analog-todigital and digital-to-analog data
acquisition systems. TI’s ultra-lowpower MSP430 microcontroller family,
or a member of one of these three DSP
families — TMS320F28x,
TMS320DM64x and TMS320C64x™
— can easily manage signal processing tasks. TI’s wired and
wireless interface integrated circuit
products can facilitate a variety of
data transmission tasks. For more information on TI’s offering
for Medical Instruments, please visit
www.ti.com/medicalinstruments
Ultrasonics
Ultrasonic technology is not often
thought of when leveraging ultra-highperformance analog and embedded
processing technology. Today, ultrasonic
devices are commonly used for cell disruption and homogenization for a broad
range of liquid processing applications,
such as:
• Emulsification
• Reaction acceleration
• Dispersion
• Fine mixing
• Degassing
Ultrasonic technology is typically
used for therapy, dermally administered drugs and skin/wound therapy. Ultrasonic waves are generated at a
frequency above 20 kHz to avoid audible detection and are propagated in a
gaseous liquid or solid medium. One
benefit of utilizing ultrasonic waves is
the esoteric directional nature of this
technology, which can be focused
onto the density and elasticity of the
medium of interest. Piezoelectric transducers are commonly
used to convert electrical oscillations
to corresponding mechanical vibrations, resulting in intense agitation of
the medium of choice. This intense
127
disturbance causes millions of microscopic cavities or voids to form and
collapse, which is known as cavitation. When the cavities collapse or implode,
they release energy and produce the
desired effect. Endoscopes
In medicine, an endoscope is used
to look inside the body to examine
the interior of a body cavity or hollow
organ such as gastrointestinal, respiratory and urinary tracts. A rigid or flexible
endoscope tube is inserted into the
body through a natural body orifices or
small incision to provide images of the
organs. Surgical instruments are often incorporated into the endoscope to enable
minimally invasive procedures such as
biopsies and removal of polyps. Some
common procedures include colonoscopy, gastroscopy, angioscopy and
bronchoscopy.
The primary components of an endoscope include a light source, a tube
to guide the light, a lens or fiber optic
system to capture reflected light of the
organ and an image capture system to
process, display and store images. For
more information, refer to endoscope
section on page 139. Smart Pills
First introduced in 1992, a smart pill
refers to any pill that delivers or controls
the delivery of medicine without patient
intervention beyond consuming the
device. The most common application is controlled drug delivery within the
gastrointestinal tract. Other applications include monitoring or electronic
stimulation of the gastrointestinal tract
to achieve the desired result, combined
with a controlled pharmaceutical delivery. Variables such as time, temperature, pressure, pH and/or location within the intestinal tract are
monitored and measured. Texas Instruments 2010
Medical Instruments
➔ Overview
Common smart-pill system components include analog signal conversion,
data processing, an RF transceiver (ISM band or other) and the conversion
of digital signals for actuator control. A
patient can wear a data receiver, and
the receiver will provide data that can
be downloaded at a later time. The data
receiver commonly comprises an RF
transceiver, potential data processing
and memory for data storage.
Surgical Robotics
Sophisticated surgical robots now
enable complex surgery using minimally invasive approaches. These systems consist of a surgical control
system leveraging pressure, acceleration and angular rate sensors interfaced to high-performance amplifiers
and data converters on the front end,
then coupled to embedded processors
communicating with robotic arms containing several degrees of motion and
low-voltage DC motors. Some systems
can also include a high-definition or
stereoscopic 3-D display/vision system. These systems filter and translate
the surgeon’s hand movements into
minute and precise movements of the
robotic arms and attached medical
instruments. Robotic Prosthetics
Robotic prosthetics are being adapted
to work with various control systems. The electrical system required is much
like a surgical robot, with the exception
that one such approach being tested
today includes an interface to myoelectric switches, which are wired to
residual nerves and muscles in the
upper body and respond to movement
impulses from the brain. Robotic prosthetics are now being controlled by
thought. Medical Applications Guide
In addition, by combining carbon nanotubes with a specially designed polymer, researchers are making a material
that looks, feels and functions like
human skin. This synthetic skin could
lead to next-generation prosthetic arms
with which patients could experience
the sense of feel, shake hands and
more easily perform ordinary tasks. The most important feature of flow
cytometric analysis is that large numbers of particles (100,000 or more) are
analyzed one after the other, typically
in about one minute. The detection limit
is as low as 100 fluorescent molecules
per cell. Submicron particles, such as
small bacteria and picoplankton, are
well resolved. Flow Cytometry
Flow cytometry is the measurement
(“meter”) of single-cell (“cyto”) characteristics suspended in a flowing saline
stream. A focused beam of laser light
illuminates each moving cell and light
is scattered in all directions. Detectors
placed in front or to the side of the
laser beam’s intersection point receive
pulses of scattered light and convert
them into a form suitable for computer
analysis and interpretation. The total
amount of detected forward-scattered
light depends on cell size and refractive index, but is closely correlated with
the cross-sectional area of the cell as
seen by the laser. The amount of sidescattered light can indicate nuclear
shape or cellular granularity. In contrast to microscopic analysis,
which is based on a very limited
number of cells seen on a slide (1 to
100), a flow cytometer provides useful information about a broad range of
cells and their functions. Fluorescence
analysis makes it possible to quantify
fluorescence from single cells up to
millions of cells after a single sample
run from one test tube. Statistical data
(like the mean fluorescent intensity and
its shifts in time or dependence on cell
function) has proven very reliable. The improved signal-chain concept
shown below supports the dynamic
range, speed and linearity required
to transfer the signal stream from the
photodiodes to the processor. The
differential signal transmissions over
twisted-pair lines provide commonmode noise rejection and therefore a significant improvement in signal quality. Better signal quality ensures
more accurate measurements and
more reliable statistical analysis. 128
Key features of flow cytometry include:
• Minimal analog errors
• Miniaturization
• Increased analysis speed for pulse
throughput
• Increased flexibility for pulse-shape
analysis
• Eventual power reduction for
battery-operated equipment
Texas Instruments 2010
Medical Instruments
➔ DLP® Technology
DLP® Discovery™ 4100
Get more information at: www.ti.com/mems
Key Features
The D4100 Kit offers developers high perform­ance and high resolution with the
0.95" 1920 x 1080p 2xLVDS DLP chip, an optical semiconductor module that
allows developers to manipulate light digitally. When integrated with a light source
and optics, this unique device creates binary light patterns with speed, precision
and efficiency surpassing that of other spatial light modulators. The D4100 Kit
provides performance improvements including increased data rate, frame rate and
flexible, random row addressing. The D4100 also supports the 0.55" diagonal and
0.7" XGA 2xLVDS chipsets.
• ±12° mirror operation
• Fill factor > 91percent
• Works with visible, near-infrared and
ultraviolet light
• DMD: Options include 0.95" 1080p,
0.7" XGA, 0.55" XGA 2xLVDS
• DAD2000 power and reset driver
• Generates reset control of 16
banks of DLP mirrors
• DDC4100 digital controller
• Provides high-speed (400MHz)
LVDS data and control interface
and provides mirror reset and
timing information to the DAD2000
• Supports random row addressing
The DLP Discovery 4100 chipset features the DLP chip and other supporting components. Unlike TI DLP controllers optimized for projection display, the D4100
is designed to support a wide variety of DLP-based applications by delivering maximum flexibility in
Reset
Texas Instruments Control
format­ting and sequencing
DAD2000
data light patterns.
Reset Driver
Texas Instruments
DMD
DDC4100 User
Interface
Applications
• Vascular imaging
• Phototherapy
• Chemical analysis
• Micro-array development
• 3-D metrology
• Genomics
Mirror
• Surgical lighting
(2 states)
“Off”
State
(–12°)
“On”
State
(+12°)
Flat Position
(No control input)
Texas Instruments
DDC4100
Data and
Control
DLP Discovery 4100 chipset block diagram.
Light
Dump
48°
te
ta y
S
ff rg
O ne
E
t
Fla y
rg
e
n
E
24°
Projection
Lens
On-State
Energy
Illum
0°
inat
ion
F
Light
Source
D –24°
F/# = F/D = 2.4
for 11.5° beam
How the light is steered.
DLP Discovery 4100 starter kit.
DLP Discovery 4100
DMD (Digital Micromirror Device)
Array
Mirror Pitch
Window Options
(Visible, Ultraviolet, Near Infrared)
Clock Rate (Maximum)
Data Rate
Binary Frames Per Second (Maximum)
0.55-inch XGA
0.7-inch XGA
0.95-inch 1080p
1024 x 768
1024 x 768
1920 x 1080
10.8µm
13.68µm
10.8µm
VIS
VIS, UV, NIR
VIS, UV
400MHz (2 x LVDS)
400MHz (2 x LVDS)
400MHz (2 x LVDS)
25.6GbPs
25.6GbPs
48GbPs
32,552
32,552
23,148
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
129
Texas Instruments 2010
Medical Instruments
➔ DLP® Technology
DLP® Pico™ Projector Development Kit v2
DLP1PICOKIT
For more information, visit www.ti.com/mems
Key Features
• Very small form factor, 44.8 x 67.4 x 14.2mm3
• Direct connection to a PC, via a HDMI or DVI port
• Selectable DMD pattern rates, up to 2400Hz
• Sync signal output
• Auxiliary connector, for direct access to I2C bus
Applications
• Portable display devices
• 3-D optical measurement
• Augmented reality
• Embedded display devices
• Microscopy
• Medical imaging
The DLP Pico Projector Development Kit v2 enables developers to integrate DLP
Technology into innovative and portable applications. The projection device utilizes
the DLP 0.17-inch HVGA chipset with a light engine containing three solid-state
color LEDs as a low-power light source. The kit includes a power supply, video
cable and HDMI-to-DVI adapter. The DLP Pico Projector Development Kit is a fully integrated projection solution that enables a vast array of new and portable
medical devices.
Pico Projector Specifications
DMD Resolution
0.17-inch HVGA
Brightness
Up to 10 lumens
Contrast ratio
1000:1
Light source
Solid-state 3 LED
Video input
DVI-D 888RGB VGA 50 and
60Hz
Dimensions
44.8 x 67.4 x 14.2mm3
DLP Pico Projector Development Kit.
DLP 0.17 HVGA Chipset
Functions
Benefits
DLP1700
GPN
(DMD) Digital
Micromirror Device
Description
MEMS component containing an array
of aluminum micromirrors, atop a CMOS
substrate, that digitally switch in a binary state
Fast and reliable spatial
light modulator to
enable light processing
and embedded display
applications
DLPC100
DMD Digital
Controller
Conveniently interfaces user electronics to
the DMD
Provides developers the
flexibility to control the
mirrors independently
and at high speeds
DLPR100
Controller
Configuration PROM
Contains the DMD digital controller
program data
Enables more advanced
spatial light modulation
than found in traditional
projection systems
DVI
Receiver
5VDC
24-bit RGB DATA
Voltage Control
Voltage
Regulator
Illumination
Optics
I 2C
IC
2
MSP430
Control
5V
TI
DLPC100
RGB ENABLE
LED
Driver
Projection
Optics
DLP1700
Configuration
Mobile
SDR
Memory
DLPR100
OSC
Block diagram of projection system using 0.17 HVGA chipset.
Medical Applications Guide
130
Texas Instruments 2010
Medical Instruments
➔ Design Considerations
Motor Control Example
5 V/TTL
Temperature
Sensor
MicroController
Controller
Interface
Voltage
References
Isolation
LEGEND
Processor
Interfac e
RF/IF
Amplifier
PWM
Motor
Solenoid
Drive
Circuit
ADC
DAC
Battery
Battery
Management
System
Power
Core and
I/O Power
Current
Sense
Auxiliary Input
Relay/LED
Driver
OR
Miscellaneous
I/O
Auxiliary Output
Optional
Battery
Solenoid
or Motor
Hi-V
Op-Amp
ADC
Logic
Power
ADC/DAC
Clocks
Other
9 V+
9+V
Motor
Power
AC Adapter
AC/DC
Supply
Plug
AC Line
Given the broad nature of this medical
subsegment, design considerations
are broken down into some popular
motor control and sensor interface
applications. Simple system block diagrams are provided along with analog
and embedded processing solutions.
Referring to the motor control block
diagram example, small electromechanical drives can include solenoid
drives, single-direction small electromechanical drives include solenoid
drives, single-direction DC, bidirectional DC or brushless DC systems and are typically sized according to their frame size and power
in watts. Digital controllers, software, and complementary analog and digital solutions from TI can help solve most
drive requirements. Medical Applications Guide
Core Subsystems
Controllers
TI offers a range of solutions for the
control processor, from the ultra-low
power MSP430 microcontroller to the
C2000™ and Stellaris® ARM® Cortex
M3 microcontrollers. The right controller can optimize motor drive efficiency,
improve reliability and lower overall
system costs. The 32-bit DSP-class
performance- and motor-control optimized on-chip peripherals of C2000
controllers enable users to easily
implement advanced algorithms such
as sensorless vector control of threephase motors. The C2000 DSC family
offers software-compatible controllers
ranging from the low-cost F28016 to
the industry’s first floating-point DSC,
the TMS320F28335.
131
Motor/Solenoid Drive Circuit
PWM drivers like the 1.2-A DRV104 are
compatible with resistive or inductive
loads for driving solenoids or valves
from a single supply. New PWM power
drivers such as the DRV8811 provide
an integrated stepper motor solution
that includes two H-bridge drivers as
well as microstepping indexer logic for
stepper control. For higher drive currents, try a high-voltage, high-current
op-amp with a current limit between
0 and 5 A (OPA548) externally controlled via a resistor/potentiometer or a
current-out DAC like the DAC7811 or
DAC8811. MOSFET drivers such as
UCC37321 or the UCC37323 can drive
small motors directly or drive power
devices such as MOSFETs or IGBTs. Note: “Motor Control Guide” (slyy017)
www-s.ti.com/sc/techlit/slyy017
Texas Instruments 2010
Medical Instruments
➔ Design Considerations
Isolation
TI digital isolators have logic input and
output buffers separated by TI’s silicon
dioxide (SiO2) isolation barrier, providing
4 kV of isolation. Used in conjunction
with isolated power supplies, these
devices block high voltage, isolate
grounds, and prevent noise currents
from entering the local ground and
interfering with or damaging sensitive
circuitry. Designers might consider the new
ISO1050, which is a galvanically isolated CAN transceiver that meets
or exceeds the specifications of the
ISO11898 standard, with IEC 61010-1
approval pending. As a CAN transceiver, the ISO1050 provides differential transmit capability to the bus and
differential receive capability to a CAN
controller at signaling rates up to 1 megabit per second (Mbps). Designed for harsh environments, the
ISO1050 provides additional features
such as failsafe outputs, 50-kV/µs transient immunity, and the 3.3-V
inputs are 5V-tolerant. Motion Feedback
Isolated delta-sigma modulators
(AMC1203/AMC1210) are ideal for
shunt measurements to flatten glitches
and increase current feedback resolution. These modulators are easy to use
and provide oversampling and filtering
for an encoder. For measuring controller inputs and system feedback,
the INA159 difference amplifier provides ±10 V (20-V pp) signals
for an analog-to-digital converter
(ADC) using 5-V or 3.3-V supplies. ADCs like the ADS7861/ADS7864 or
ADS8361/ADS8364 provide four- or
six-channel simultaneous current
sampling. The INA19x (x = 3 to 8) and
INA20x (x = 1 to 9) provide wide common-mode voltages and are capable
of both low-side and high-side current
shunt monitoring. Controller Interface
USB, RS-232 or RS-422 are adequate
for many systems. RS-485 signaling may be bundled with protocols
such as Profibus, Interbus, Modbus
or BACnet, each tailored for the
specific requirements of the end
user. Sometimes CAN or Ethernet/
IP (industrial protocol) are preferred
due to network requirements. M-LVDS
can provide a lower power dissipation
alternative. See the application note at
www.ti.com/comparingbussolutions
for additional information on interface selection.
Sensor Signal Chain
Weigh Scale Sensor Example
LCD
Backlight
LCD
Display
Data Transmission
ZigBee
Bluetooth
Filtering
No Gain Stage
Low Power Wireless
Embedded
Processor
USB
Controller
Gain
Transient
Protection
USB Port
Gain Stage
USB Power
Load Cell
Keypad
Legend
Plug
AC
Adapter
System
Power
AC Line
Medical Applications Guide
132
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Texas Instruments 2010
Medical Instruments
➔ Design Considerations
Sensor Signal Chains
Pressure Sensor Signal Chain Example
Nonlinear Integrated
Bridge
Solution
Transducer
P
psi
0 50
Linearization
Circuit
VEXC
VRef
Analog Output
DAC
4-20 mA
Analog Sensor Linearization
Over/Under
Scale Limiter
Fault
ADC
Analog Signal Conditioning
+125ºC
Digital
Temperature
Compensation
T
-40ºC
TMP
ADC
VRef
Clock
RF/LPW
Processor
CAN
Control
Registers
RS232/
RS485
LEGEND
Core
and I/O
Power
Low
Noise
Power
Power Management
Flow Meter Sensor Signal Chain
Example
Common
Interfaces
DC Power
Source
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Common
Interfaces
VRef
Clock
RF
CAN
ADC
Processor
RS232/RS485
4-20 mA
Driver
The Magnetic-Inductive Flowmeter
Common
Interfaces
VRef
Clock
RF
CAN
ADC
Processor
RS232/RS485
4-20 mA
Driver
Low
Noise
Power
ADC
The Coriolis Flowmeter
Core
and I/O
Power
Power Management
Medical Applications Guide
133
LEGEND
DC Power
Source
Processor
Interfac e
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Texas Instruments 2010
Medical Instruments
➔ Design Considerations
Sensor Interface
Electronic weigh scales, pressure sensors and flow meters are among the
most common forms of measurement
in the medical instrumentation market. Manufacturers of medical instruments
occasionally develop proprietary ASICs
to tailor the performance of the analog front end for the highest accuracy
and stability possible, while maintaining an IP edge over their competition. Although TI supports and encourages
this custom ASIC approach, there are
design approaches using standard
products offering up to 23 noise-free
bits of resolution, which parallels the
performance of customized solutions. A major challenge in designing for
these sensor interfaces is the sampling of multiple load cells while offering extremely low referred-to-input
(RTI) noise. The ADS1230, ADS1232
and ADS1234 offer the low RTI noise
required in this application. Another important factor is the analog circuitry’s long-term stability with
regard to offset drift and gain over time
and temperature, especially since realworld sensors have span and offset
errors ever changing as temperatures
rise and fall. In addition, many bridge
pressure sensors have a nonlinear
output with applied force. Here, the
accuracy of the amplified input signal,
either single-ended or differential, must
be guaranteed over years of operation. Auto-zero amplifiers such as the
OPA335 and the INA326 instrumentation amplifier easily meet these stringent requirements by achieving offset
drifts of 0.05µV/°C (OPA335) and 0.4µV/°C (INA326). There are highly integrated solutions
as well, such as the PGA309, tailored
for bridge pressure sensors. These
sensors comprise precision, low-drift
programmable gain instrumentation
amplifiers using auto-zero techniques
and include programmable fault monitors and over/under scale limiters. The
Medical Applications Guide
PGA309 also offers a digital temperature compensation circuit. If temperature compensation is not required, try
the PGA308. Other recommended lowest noise
amplifiers and instrumentation amplifiers for pressure sensor conditioning include the OPAx227, OPAx132,
INA118, INA122 and INA333.
The INA333 is becoming a popular
choice for several applications within
medical instrumentation, selected for
its low power, high accuracy and gainsetting capabilities. A single external
resistor sets any gain from 1 to 1,000
using the standard gain equation G = 1 + (100kΩ/RG). Analog to Digital Conversion
For analog to digital conversion, the
ADS125x family of devices are well
suited. These are precision, wide
dynamic range, delta-sigma ADCs with
18- to 24-bit resolution operating from
a single +5V supply and guaranteed
to have no missing codes. They are
designed for high-resolution measurement applications in cardiac diagnostics
and medical instrumentation. If multi-axis motor control is required,
consider the new ADS8556/7/8 converter family. These ADCs contain six
low-power, 16-, 14- or 12-bit successive
approximation register (SAR)-based
analog-to-digital converters (ADCs)
with true bipolar inputs. Each channel
contains a sample-and-hold circuit that
allows simultaneous high-speed multichannel signal acquisition supporting
data rates of up to 740kSPS in parallel
interface mode, or up to 500kSPS if the
serial interface is used. As appropriate
for motor control application, a wide
input configuration range is possible
from ±1V to ±12V. 134
Clocks
The CDCE9xx clock family comprises
modular, PLL-based, low-cost, highperformance, programmable clock
synthesizers, multipliers and dividers. They generate up to nine output clocks
from a single input frequency. Each
output can be programmed in-system for any clock frequency up
to 230MHz using independent configurable PLLs.
Power
Low dropout regulators (LDOs) are
good for low noise power for amplifiers and data converters because they
provide low-ripple power rails leading
to better signal fidelity. The REF31xx
family comprises precision, low-power,
low-dropout series voltage references
available in a tiny SOT23-3 package. The REF31xx does not require a load
capacitor, but is stable with any capacitive load and can sink/source up to 10 mA of output current.
Embedded Processing
OMAP™/DaVinci™ Processors
One of the most important features in
today’s medical instruments is ease
of use. Ease of use can be achieved
with touch-screen displays and multilevel menu-driven profiles that can be
configured for the environment as well
as the patient’s vital statistics. Data
transfer across everything from wireless to RS232 needs to be possible as
well. Hospitals may support a specific
infrastructure throughout all areas;
ambulance, home and other environments may need support for different
protocols. Texas Instruments 2010
Medical Instruments
➔ Design Considerations
The challenges in implementing this
ease of use is strikingly similar to cellular phone systems. TI’s OMAP
technology with embedded ARM ®
and DSP processor cores directly
addresses these challenges. The
OMAP 3 processor performs further
digital signal processing, measurements and analytics to monitor
equipment and patient conditions. A powerful ARM processor runs a
high-level OS (HLOS), which makes
adding multi-modal equipment control
monitoring easy and provides extensive user interface and system control. Detecting abnormal conditions or
faults and communicating to a central
server or health care provider is essential. OMAP 3 has an extensive peripheral set to support various control and
interface/connectivity options such as
Bluetooth® technology, WiFi, ZigBee®
and other emerging standards. C5000™ Processors
TI’s TMS320VC5504/05/14/15 DSPs
offer the industry’s lowest standby
power consumption (<150µW) and the industry’s lowest active power consumption (0.15mW/MHz). These two new pin-to-pin compatible processors maximize energy efficiency,
extending battery life for portable
devices while reducing system cost
and enabling user-friendly features. While successful in the portable monitoring space, these devices also find
Medical Applications Guide
themselves well positioned for the
medical instrumentation segment, providing high integration of peripherals
such as a 1024-point programmable
fast Fourier transform (FFT) hardware
accelerator, a high speed USB 2.0 with
physical layer (PHY), LCD display controller, and a MultiMedia Card/Secure
Digital (MMC/SD) and 10-bit, fourchannel successive approximation register (SAR) analog-to-digital converter. The Stellaris® MCU Family of
Processors (Luminary)
Medical instrumentation requires accuracy, reliability and responsiveness. Whether connected or standalone,
Stellaris processors offer solutions
useful to medical equipment manufacturers. Safety is enhanced through an
MPU (memory protection unit), multiple
error detection mechanisms in the processor, peripheral fault detection, priority of interrupts to handle
faults and critical operations, and
a highly deterministic operation. Communications include Ethernet and serial for connected devices.
Stellaris MCUs and ARM Cortex-M3
offer a direct path to the strongest
ecosystem of development tools, software and knowledge in the industry. Designers who migrate to Stellaris
will benefit from great tools, small
code footprints and outstanding
performance. 135
The Stellaris family offers the industry's
first and broadest implementation of
Cortex-M3 and the Thumb-2 instruction
set. With blazingly fast responsiveness,
Thumb-2 technology combines both
16- and 32-bit instructions to deliver
the best balance of code density and
performance. Thumb-2 uses 26 percent
less memory than pure 32-bit code to
reduce system cost while delivering 25
percent better performance.
Newly acquired into TI's expansive
microcontroller portfolio, Stellaris microcontroller users will benefit from:
• Assured product longevity, with the
backing of a global top-three semiconductor supplier with more than 75 years of industry experience. • Access to and support from a large
direct global sales force, in addition to extensive global distribution
access. • Ability to pair your Stellaris MCU with
the complete signal chain and power
management solutions, support and
applications know-how that only TI
can offer. The era of pervasive 32-bit computing,
control and communication has arrived.
Other Embedded Processors
The MSP430 microcontroller or
TMS320C55x DSP provides functions
including calculation and signal processing, a friendly user interface such
as LCD display and keypad control, and
wireless/wired data transfer and connectivity interfaces. TI's MSP430 and
MSC12xx integrated microcontroller
solutions family allow the definition of
filters and thresholds of critical pressure
levels by including integrated ADCs.
Texas Instruments 2010
Medical Instruments
➔ Component Recommendations
Amplifiers
Component
Description
Key Features
Benefits
Other TI Solutions
PWM High-Side
1.2A output drive, +8V to +32V supply range
Driver Amp for
Solenoids, Coils
High-Speed,
Gain of 0.2 to interface ±10V signals to single-supply ADCs
Precision Gain
Level Translation
Difference Amp
Low Power, Precision 25μV (max) offset, 50nV/°C drift, 50μA (typ) Iq
Instrumentation Amp
PWM operation conserves power and allows for fine
control
OPA211
Precision Op-Amp
1.1nV/√Hz at 1kHz low noise, 0.2µV/°C offset drift,
80MHz (G = 100) BW
<1µs settling time to 16-bit accuracy
OPA277
Precision Op-Amp
10µV offset voltage, ±0.1µV/°C low drift, 134dB open-loop
gain, 140dB CMRR
Available in S, D, Q
OPA177, OPA627
OPA380
90MHz GBW, over 1MHz transimpedance BW, 25µV offset
(max), 0.1µV/°C drift (max)
Precision, dynamic range 4 to 5 decades, excellent
long term stability
OPA350, OPA335
OPA735
Transimpedance
Amp
CMOS Op-Amp
0.05µV/°C zero drift (max), 750µA IQ (max), 5µV offset
voltage
Zero-drift series, dual version available
OPA734
OPA827
JFET-Input Op-Amp
1µV/°C drift, 4.5mA/ch IQ, 250µV offset voltage, 18MHz BW
Outstanding DC precision w/excellent AC performance
OPA141
PGA309
Sensor error compensation: span, offset, temp drifts
Complete bridge sensor conditioner
PGA308
THS4520
Prog. Sensor
Conditioner
High-Speed Op-Amp
450MHz (G = 2V/V), 570V/µs SR, 2nV/√Hz noise
(f>10MHz)
Single-to-differential conversion
THS4131
High-Speed Op-Amp
150MHz (–3dB) BW, 51V/µs SR, –100dB HD3 at 250kHz
Low noise, fully differential I/O
THS4631
High-Speed Op-Amp
210MHz GBW, 900V/µs (G = 2) SR, –76dB SFDR at 5MHz
±5 and ±15V supply operation, 95mA output current
16-bit, 860SPS, 4 SE, 2 diff input, PGA, MUX, comparator,
VREF
24-bit, 2kSPS, 7 channels w/dual current sources, GPIO, low
drift VREF, and temp sensor
Smallest 16-bit ADC – 2.0 x 1.5 x .04 mm leadless QFN
pkg – reduces system size/component count
Flexible front end for flow or temperature measurement
ADS1113/4,
ADS1013/14/15
ADS1148, ADS1247,
ADS1147
DRV104
INA159
INA333
DRV102, DRV101
Maintains gain accuracy and common-mode rejection
over temperature
Best offset/noise combination, supply down to 1.8V,
low power
INA321, INA118,
INA326
Data Converters
ADS1115
Delta-Sigma ADC
ADS1248
Delta-Sigma ADC
ADS1258
Delta-Sigma ADC
16-channel, 24-bit, 125kSPS, 23.7kSPS/channel
Fastest multichannel delta-sigma ADC, measures all
16 inputs in <675µs
ADS1274, ADS1278,
ADS1605, ADS1602,
ADS1601
ADS1278
ADS1298
Delta-Sigma ADC
ECG/EEG AFE
24-bit, 128kSPS, 8-channel, 111dB SNR
24-bit, 8PGA, 8ADC, plus RLD and RESP
ADS1271, ADS1274
ADS1294, ADS1296,
ADS1198, ADS1251/58
ADS1605
ADS7864, ADS8361,
ADS8364
ADS1610
Delta-Sigma ADC
16-bit, 10MSPS, parallel interface
Simultaneous measurement, onboard decimation filter
Complete front end, reduction in power and size, increase
reliability
SYNC pin for simultaneous sampling
ADS7861
SAR ADC
Dual, 500kHz, 12-bit 2+2ch
Simultaneous sampling
ADS8254/55
SAR ADC
16-bit, 1MSPS, 98dB (typ) SNR, 270mW power, onboard
4V int reference, driver amp and MUX
Flexible input configuration, multichannel modes
ADS8284/85
SAR ADC
18-bit, 1MSPS, 98dB (typ) SNR, 270mW power, onboard
4V int reference, driver amp and MUX
Flexible input configuration, multichannel modes
ADS8317
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
Excellent linearity, micropower, high speed
ADS8422
ADS8326
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
Low noise, low power, high speed
ADS8325
ADS8410
SAR ADC
16-bit, 2MHz, 87.5dB at 10kHz I/P SNR, int. ref.
200Mbps LVDS serial interface
ADS8413
ADS8413
SAR ADC
16-bit, 2MSPS, LVDS interface int. ref. and buffer
LVDS, serial interface, daisy-chain capable
ADS8410, ADS8406
ADS8422
SAR ADC
16-bit, 4MSPS, 1 LSB INL (typ), parallel interface
Zero latency
ADS8412, ADS8472
ADS8556
SAR ADC
16-bit, 6-channel, ±1V to ±12V input configuration
Six SAR ADCs grouped in 3 pairs, pin selectable input range
ADS8557, ADS8558
DAC7811
Multiplying DAC
12-bit, single channel, serial input, multiplying DAC
Multiplying, current output
DAC7613, DAC8811,
DAC8871
DAC8550/2/4
Low-Power DAC
16-bit, 1-4 chs, ±3 LSB (typ) INL, 0.1 to 0.15nV-s glitch
Excellent AC/DC performance
DAC8560, ADS8564
DAC8560
VOUT DAC
16-bit, 0.15nV-s glitch, ±10µs to 0.003% FSR settling time
Small package, low power
DAC7731, DAC8411
DAC8564/5/8
Quad DAC
16-bit, 2.5V VREF, 2ppm/°C drift, 0.15nV-s glitch
Quad and octal versions
DAC8551
DAC8812
MDAC
16-bit, ±1-LSB INL, –105dB THD, 0.5µs settling time
Multiplying, current output
DAC8814
DAC8814
Multiplying DAC
16-bit, 0.5µs settling time, –105dB THD, 1 LSB (max)
relative accuracy
Double-buffered serial data interface
DAC7715, DAC8811
DAC8820
DAC
16-bit, parallel input multiplying, ±1.5 LSB DNL, ±1 LSB INL
2.7V to 5.5V supply, low noise, low power
DAC8814, DAC8822
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Medical Applications Guide
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136
Texas Instruments 2010
Medical Instruments
➔ Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Data Converters (Continued)
TPDxE001
ESD Protection
Industry's lowest leakage spec, 15kV ESD solution in
two-, three-, four- and six-channel packages
-3dB bandwidth at 200MHz, 15kV contact ESD, and four-,
six- and eight-channel available
Back-to-back clamp for bipolar signal interface
System-level ESD protection for USB 2.0, Ethernet,
analog I/O interfaces
System-level EMI immunity for high-speed data
interface
System-level ESD protection for RS485, RS422,
RS232, LVDS, and CAN interfaces
System-level ESD protection for HDMI, eSATA,
USB 2.0, and DisplayPort high-speed interfaces
TPDxE004
TPDxF003
EMI Filter
TPD2E007
ESD Protection
TPD4S009
ESD Protection
Industry's lowest leakage spec, less than 0.05pF
differential capacitance
TXS0102
Autodirection
Sensing VoltageLevel Translator
2-bit, 1.2V to 5.5V, works with push-pull and open drain
(e.g. I2C) drivers
Bridges incompatible digital switching voltages
TPDxE001
ESD Protection
EMI Filter
TPD2E007
ESD Protection
TPD4S009
ESD Protection
TXS0102
Autodirection
Sensing VoltageLevel Translator
System-level ESD protection for USB 2.0, Ethernet,
analog I/O interfaces
System-level EMI immunity for high-speed data
interface
System-level ESD protection for RS485, RS422,
RS232, LVDS, and CAN interfaces
System-level ESD protection for HDMI, eSATA, USB
2.0, and DisplayPort high-speed interfaces
Bridges incompatible digital switching voltages
TPDxE004
TPDxF003
Industry's lowest leakage spec, 15kV ESD solution in
two-, three-, four- and six-channel packages
–3dB bandwidth at 200MHz, 15kV contact ESD, and four-,
six- and eight-channel available
Back-to-back clamp for bipolar signal interface
TPD6F002
TPD2E009,
TPD8S009,
TPD4S010
TXS010x, TXB010x,
SN74AVCxxT245
Interface
Industry's lowest leakage spec, less than 0.05pF
differential capacitance
2-bit, 1.2V to 5.5V, works with push-pull and open drain
(e.g. I2C) drivers
TPD6F002
TPD2E009, TPD8S009,
TPD4S010
TXS010x, TXB010x,
SN74AVCxxT245
Clocking Products
CDCE(L)9xx
1.8V Programmable
VCXO Multi-PLL
Clock Synthesizer
LVCMOS or Xtal Inputs; VCXO Input with ±150ppm (typ)
pulling range
Low power consumption, low jitter, low skew;
EEPROM programmable
CDCE706, CDCE906
CDCE72010
2:10 Ultra-Low Jitter
Cleaner w/ VCXO
Wide-range integer divide; <35fs RMS jitter; on-chip
EEPROM
Wide input/output freq. range supports high and low
end of freq. standards
CDCE6200x
CDCM6100x
1:4/2/1 Xtal-In
44MHz - 683MHz
Clock Generator
Fully integrated VCO and loop filter generates various
frequencies; <1ps RMS jitter
One single device across multiple designs, replacing
up to four discrete XOs
CDCS50x
Xtal-In Clock
Generator with
Optional SSC
Selectable multiplier rates of 1x and 4x; selectable spreadspectrum modulation
Reduces EMI up to 10dB; replaces more costly crystal
oscillators
15ppm/°C, 0.2% accuracy at 25°C
Low power consumption, low dropout.
Triple processor supervisor
Two fixed and one adjustable supervisor for system
flexibility
Protection from short between any pins and between
any pin to ground
Flexible, fail safe solution
Power Products
REF3130
TPS3307
TPS61081
TPS61093
TPS62110
TPS62400
TPS62750
TPS63000
TPS63030
TPS717xx
TPS718xx-yy
TPS74201
TPS74401
TPS74701
TPS79901
UCC37321
SOT23-3 Series
Voltage Reference
Voltage
Supervisor
LED Boost
Converter
OLED Boost
Converter
Step-Down
Converter
Dual Output StepDown Converter
Step-Down
Converter
Buck-Boost
Converter
Buck-Boost
Converter
Single-Channel LDO
Dual-Channel LDO
Single-Channel LDO
Single-Channel LDO
Single-Channel LDO
Single-Channel LDO
Single 9A Peak
Low-Side
MOSFET driver
Input-to-output isolation
Wide VIN range, input-output disconnect
3.1V to 17V VIN, 1.5A conversion, synchronization pin, Low
battery indicator, power save mode
180° out of phase operation, serial interface
Programmable input current limit, hot plug and reverse
current protection
1.8A switch, automatic transition between step down and
boost mode
1A switch, automatic transition between step down and boost
mode
Very high rejection of power-source noise
Very high rejection of power-source noise
1.5A ultra-low-dropout linear regulator
3.0A ultra-low-dropout linear regulator
0.5A ultra-low-dropout linear regulator
Very high rejection of power source noise
High-speed, 20ns typical rise and fall times
REF3112, REF3120,
REF3125, REF3133
TPS3808
TPS61042
TPS61080
Very low noise/high efficiency
TPS62050
Flexible voltage adjustment for processors and MCUs
TPS62410
Supports USB powerde applications and large.output
caps
Stable output voltage over entire entire VIN range
TPS62040
Extending Application run time, Small Solution
TPS61020
Low-noise power rails for sensitive analog components
Low-noise power rails for sensitive analog components
Split bias and supply pin minimize heat generation
Split bias and supply pin minimize heat generation
Split bias and supply pin minimize heat generation
Low-noise power rails for sensitive analog components
Industry standard pin-out, handles extreme Miller
currents
TPS799xx
TPS719xx-yy
TPS74301, TPS74801
TPS74901
TPS63010
TPS79501
UCC37323
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
137
Texas Instruments 2010
Medical Instruments
➔ Component Recommendations
RF Transceivers
Component
CC1101
Description
Sub-1GHz RF
Transceiver
Key Features
Wake-on-radio functionality; integrated packet handling
with 64-byte data FIFOs; high RF flexibility: FSK, MSK,
OOK, 1.2-500Kbps; extremely fast PLL turn-on/hop time
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temperature
range; AES-128 security module
Benefits
Ideal for low-power systems; any low-end MCU
can be used; backwards-compatible with existing
systems; suitable for fast frequency-hopping systems
Reliable RF link with interference present; 400-m
line-of-sight range with the development kit; ideal for
industrial applications; no external processor needed
for secure communication
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
MCU, USB 2.0, flash and RAM in one package; four flexible
power modes for reduced power consumption; includes
CC1101 transceiver frequency synthesizer; built-in
AES-128 encryption coprocessor
System-on-Chip
Solution for
ZigBee® location
engine
Second Generation
System-on-Chip
Solution for 2.4GHz
IEEE 802.15.4/
RF4CE/ZigBee
2.4GHz
Bluetooth® Low
Energy compliant
RF System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
CC2431 has 32/64/128 KB hardware AES encryption
engine, excellent selectivity, blocking performance and
hardware location
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power, battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
Ideal for battery operated systems; suitable for
proprietary and ZigBee systems; adds location
awareness and accuracy of 3 to 5 meters
RF System-on-Chip
CC2560
CC1110/11
CC2431
CC2530/31
CC2540
WL1271
WL1273
Other TI Solutions
CC2500
CC2530
CC2510, CC2511
Excellent RX sensitivity, low power, easy-to-use
development tools
RF design SOC for quick time to market; provides a
robust and complete ZigBee USB dongle or firmwareupgradable network node
CC2590/91,
CC2530ZNP
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity, selectivity
and blocking performance
A fast-to-market Bluetooth® low energy compliant
solution
Single-chip 802.11b/g/n WLAN and Bluetooth® solution
using TI’s digital radio processor technology using a single
antenna.
Single-chip 802.11a/b/g/n WLAN and Bluetooth® solution
using TI's digital radio processor technology using a single
antenna.
Sophisticated low-power technology ideal for battery operated
solutions; coexistence features enable simultaneous WLAN
and Bluetooth® operations; supports ANT+ standard.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
Second
Generation
Z-Stack™
Network Processor
ZigBee® stack and radio in one chip; implements ZigBee
certified stack; configurable device type and network
settings
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery-operated excellent selectivity and
blocking performance systems; excellent coexistence
with Bluetooth® technology and Wi-Fi.
Applications
Processor
Stellaris®
Microcontroller
Microcontroller
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
High performance at handheld power levels
AM3505
ARM® Cortex M3 core, 50MHz, 64kB single-cycle flash
Hardware-division and single-cycle multiplication,
21 interrupt channels
Ultra-low-power, integrated SoC
LM3S600
PowerVR SGX graphics accelerator, HD resolution
output
OMAP3525,
OMAP3515,
OMAP3503
WL1273
WL1271
RF Network Processor
CC2530ZNP
Processors
AM3517
LM3S800
MSP430FG461x
OMAP3530
Digital Signal
Processor
OMAP-L137
Low-Power
Applications
Processor
TMS320F2803x
Microcontroller
TMS320VC5505
Digital Signal
Processor
Ultra-low power, 16-bit operation, up to 120kB flash, up
to 8kB RAM, 12-bit ADC, 12-bit DAC, three op-amps, LCD
controller
Low power 64x + ARM® Cortex-A8 CPU, 3440 MMACS,
720MHz
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
32-bit operation, 60MHz, up to 128kB flash, up to 20kB
RAM, high-speed 12-bit ADC, high-resolution PWM
High-performance, low-power TMS320C55X DSP
generation CPU core
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
ADC capable of 5MSPS, programmable CLA (control
law accelerator)
GPIO, 10-bit SAR ADC and I/O for displays
±12° mirror operation, works with Visible, UV and near-IR
light
This device can surpass the speed, precision and
efficiency of other spatial light modulators
DLP® Pico™
44.8x67.4x14.2mm3, I2C command interface
Well suited for incorporating digital projection into
portable devices
DLP® Discovery™
TMS320VC5504
Toolkits
DLP®
Discovery™
4100
*Page 129
DLP®
Pico™ Kit
*Page 130
An optical semiconductor module
that allows digital
manipulation of light
Fully integrates
projection solutions
for portable medical
devices
*For additional product information see designated page number.
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Medical Applications Guide
New products are listed in bold red. Preview products are listed in bold blue.
138
Texas Instruments 2010
Medical Instruments
➔ Endoscopes
In medicine, an endoscope is used to
look inside the body to examine organs. Through a small incision, endoscopes
can examine gastrointestinal, respiratory and urinary tracts, as well as internal organs. An endoscope captures
images through its long tube, which can
be rigid or flexible. Additional instruments for cutting, grasping and other
functions are often attached to the endo­
scope to permit minimally invasive
procedures that improve patient care
and minimize recovery time.
When used in a technical application to
inspect confined spaces, the tool is
often referred to as a borescope. Bore­
scopes are used to inspect machinery
interiors, building walls and to search
for victims in collapsed buildings.
Endoscopes and borescopes have four
basic requirements:
• A light source to illuminate the subject
• A tube to guide the light to the subject
• A lens or fiber optic system to capture light reflected from the subject
• An image-capture system to capture,
process and store or display the image
TI’s broad product portfolio supports
the entire image chain including generating light, capturing an image, signal
conditioning and image processing. LED
drivers supply a bright light source with
excellent directionality and minimal
waste heat. These drivers are versatile
and permit LED selection optimized for
an application’s spectral requirements. The resolution of current steps impacts
illumination control precision: PWM
and analog dimming available from TI
LED drivers allow for precise illumination level and timing control.
The image sensor detects reflected
light and converts the light to an analog
electrical signal. Depending on the
image sensor’s location, low-noise line
drivers may be needed to transmit the
signal over the light tube’s length. Critical considerations for line drivers
are low power, noise immunity and
data rate. LVDS technology provides
up to 800 Mbps with voltage swings of
a few tenths of a volt and high rejection
of common-mode noise.
Biopsy Tool
Control Head
LEGEND
Processor
Interface
Essential to final image quality is the
analog front end (AFE). The AFE conditions the sensor’s analog electrical
signal and converts image information
to a digitized representation. Critical to
AFE selection is the ability to condition
the signal to correct sensor-induced
distortions such as dark current cancellation, reset level variations,
defective pixel correction and DC offset variations. Depending on the signal
level, the presence of programmable
gain amplifiers (PGAs), PGA linearity
and the range of available gains may
also be important. During digitization,
the number of bits determines image
contrast. Typically, digitizing the initial
data with two to four bits more precision than desired in the final image is
recommended. For example, if 8 bits of
final image data are required, initially
digitize to 10 bits to allow for rounding
errors during image processing. When
color reproduction is critical, differential non-linearity (DNL) and integral
non-linearity (INL) should be minimized.
Lens, Imager and
Optional Biopsy Tool
Endoscope
Electronics Head
Amplifier
Logic
Power
ADC/DAC
Other
System
Connection Cable
Need is dependent on length of scope tube and whether
AFE is in the imagining end or processing end of the scope.
Analog Video Out
Optional
Analog
Line
Drivers
CCD/CMOS
Sensor
Lens
Imager
Power
Light
Source
LED
Drivers
Low Noise
Power Rails
System Power
CCD/CMOS
Signal
Processing
(AFE)
Optional
Digital
Line
Drivers
REF
Logic
Clock
Interfaces to Display
Video
Processing
Engine
HDMI
DVI
Interfaces to PC
RS232
RS485
Ethernet
Core and
I/O Power
Memory
Power
RGB
Video
DAC
Level Shift
SDRAM
FLASH
EPROM
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Endoscope system block diagram.
Medical Applications Guide
139
Texas Instruments 2010
Medical Instruments
➔ Endoscopes
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Analog Front Ends
VSP2582
VSP2562
CCD/CMOS AFE
CCD/CMOS Analog
Front End
CCD/CMOS Analog
Front End
36MSPS, 12-bits (parallel output), CDS
36MSPS, 12-bits (parallel output), CDS, w/two
8-bit DACs
36MSPS, 16-bits (parallel output), CDS, w/two
8-bit DACs
Low noise, low power, smallest footprint
Low noise, low power, small footprint, includes two
8-bit DACs to simplify system design
Higher resolution, low noise, low power, small footprint,
includes two 8-bit DACs to simplify system design
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
Laptop-like performance at handheld power levels
TMS320DM355
Digital Media
System-on-Chip
64-channel EDMA, 135/216/270MHz ARM926EJ-S
clock rate
TMS320DM365
Digital Media
System-on-Chip
Digital Media
Processor
Digital Media
System-on-Chip
64-channel EDMA, 216/270/300MHz ARM926EJ-S
clock rate
64-channel EDMA, 400/500/600/660/700MHz
C64x+™ clock rate
64-channel EDMA, 513/594MHz C64x+ clock rate
Digital Media
System-on-Chip
Industry’s Lowest
Power FloatingPoint DSP
64-channel EDMA, 594/729/1000MHz C64x+™ clock
rate
32-/64-bit accuracy, 1.8V to 3.3V I/O supply, low power
and rich connectivity peripherals.
Encode/decode up to 720p H.264; optimized for
power, cost, and efficiency, and is even suitable for
three Li-ion AA battery inputs
Encode/decode up to 1080p H.264; high-performance
ARM® and video processing capabilities
DSP architecture means programmable solution,
Benefit from H.264 encode (D1)
Encode/decode up to 720p MPEG-4, programmable
DSP, with GUI and other processing offloaded to the
ARM® for greater efficiency and scalability
Encode/decode up to 1080p H.264; high-performance
programmable DSP and ARM
Uses three times less power that existing floatingpoint DSPs
THS8135
Video DAC
THS8200
Video DAC
Triple 10-bit 240MSPS video DAC with tri-level sync
and video-compliant (ITU-R.BT601) full-scale range
Triple 10-bit all-format video DAC
VSP2566
Processors
TMS320DM6437
TMS320DM6446
TMS320DM6467
TMS320C6747
OMAP3503,
OMAP3515,
OMAP3525
Data Converters
Amplifiers
OPA360
Video Amp
OPA3693
Video Amp
OPA830
Buffer Amp
3V video amplifier with low pass filter, internal G=2 and
SAG correction in SC70
Triple,ultra-wideband, fixed gain, video buffer with
disable
—
2.5MHz (G = +1) BW, 550V/µs slew rate, 9.2nV/√Hz
noise, 3.9mA supply current, single/dual supply
Designed to work with video processors
OPA361, THS7303
Designed to work with video processors
OPA3832
Ideal input buffer stage
OPA2830, OPA847
10MHz-66MHz; QFN and TSSOP
10MHz-135MHz, BGA and TSSOP; supports 1.8V to
3.3V TTL i/p
Available in 70% smaller QFN package
Wide frequency range, saves space, no level shifter for
1.8V powered µP
SN65LV1224B
SN75LVDS83B
Integrates charger, WLED, DCDC and LDO.
White LED driver with digital and PWM brightness
control in 2mm x 2mm package
Down to 0.7V VIN operation, pass-through function
Up to 90dB PSRR, excellent AC and transient load
regulation
180 degrees out of phase operation, serial interface
Highest integration for portable applications
Allows stepped brightness adjustment
TPS65720
TPS61061
Simple, small, low power solution
Low noise regulation, 12mm2 solution size
TPS61070
TPS62260
Flexible voltage adjustment for processors and MCUs
TPS62410, TPS62111,
TPS62260, TPS62290
TPS61020
Interface
SN65LV1023A
SN65LVDS93A
10-bit LVDS Serdes
24-bit RGB LVDS
Serdes
Power Management
TPS65073
TPS61160
PMU w/charger/WLED
White LED Driver
TPS61220
TPS62230
Boost Converter
Step-Down
Converter
Dual Output StepDown Converter
Buck-Boost
Converter
LDO
TPS62400
TPS63030
TPS71701
TPS74201
TPS74301
Single Channel
LDO
LDO
TPS74401
LDO
TPS74701
Single Channel
LDO
Linear Charge
Management
TPS75003
1A switch, automatic transition between step down and
boost mode
Low-noise, high-bandwidth-PSRR, low-dropout 150mA
linear regulator
1.5A ultra low-dropout linear regulator
Extending application run time, small solution
Single-output LDO, 1.5A, adjustable (0.8V to 3.3V), any
or no cap, programmable soft start
Single-output LDO, 3.0A, adjustable (0.8V to 3.3V), fast
transient response, programmable soft start
1.5A ultra low-dropout linear regulator
Adjust the voltage ramp rate for your processor
requirements
Adjust the voltage ramp rate for your processor
requirements
Split bias and supply pin minimize heat generation
Integrated triple-supply power management IC for
Xilinx Spartan FPGAs
Provides all three rails in one package
TPS718xx family
TPS74401
TPS71718,
TPS74801
New products are listed in bold red.
To view more system block diagram compatible products, visit www.ti.com/medical
Medical Applications Guide
Filters out wider range of incoming noise with the high
PSRR
Split bias and supply pin minimize heat generation
140
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Overview
Connectivity plays an important role in clinical, patient monitoring, and
consumer medical devices. While
wired (USB) connections continue to
be used, emphasis is being placed on wireless capabilities that enable
connected or networked devices. Portability requirements call for these
devices to be small in size, consume
minimal power and include the ability
to efficiently and accurately feed data
to remote sources.
TI has long-time experience providing a
wide range of innovative wireless tech­
nologies. Some of these technologies
include ZigBee®, radio frequency identification (RFID), low-power wireless
(ISM), Bluetooth® technology and WLAN.
USB for Medical Applications
Connectivity for portable medical
applications has become critical as
consumers and caregivers are requiring data to move from medical devices
to data hubs such as computers and
mobile phones. TI is a promoting member of the
Continua Health
Alliance and now
offers the first
Continua-certified
USB platform for Agent Devices.
See page 142 for more information.
For more information on the Continua Health Alliance, visit
http://www.continuaalliance.org
ZigBee® and Bluetooth®
Low Energy Solutions
for Medical Applications
More and more medical devices,
especially in patient monitoring and
home healthcare, can benefit from
wireless technologies such as ZigBee
and Bluetooth Low Energy. The ZigBee standard enables
companies to have a simple, reliable,
low-cost and low-power standardbased wireless platform for their
medical application development. As an example, with the use of ZigBee
wireless sensors, patients can move
around in the hospital, or even in
their homes, and the sensors will still
monitor and send critical health data to the hospital or doctor. Bluetooth Low-Energy
solutions are designed for
low-cost, low-power and
short range connectivity. The technology enables
direct communication to cellular
phones, laptops and other Bluetooth
enabled devices such as sports and
fitness watches, GPS / handhelds, and other personal monitoring devices. For more information, visit:
www.ti.com/zigbee
www.ti.com/bluetoothlowenergy
Radio Frequency Identification (RFID)
TI’s high-frequency RFID product family
consists of 13.56MHz high-frequency
(HF) transponders and low-power RFID
readers that are compliant with ISO/IEC
15693 and ISO/IEC 18000-3 global
open standards.
Typical RFID medical applications
include blood bag and medical supply
tracking, patient/staff authentication,
pharmaceutical authentication, medical
imaging, product authentication and
remote digital healthcare management
applications.
TI’s Tag-it™ HF-1 family of transponder
inlays consists of 13.56MHz HF transponders that are compliant with ISO/
IEC 15693 and ISO/IEC 18000-3 global
open standards. These products are
available in six different antenna shapes
with frequency offset for integration
into paper, PVC or other substrates
manufactured with TI’s patented lasertuning process to provide consistent
read performance.
Texas Instruments supports the ZigBee
Personal Health (PH) profile as well as
the Continua Alliance/ EN11073 profile.
Connectivity
ZigBee®/
IEEE 802.15.4
Bio Sensors
Embedded
Processor-Based
Portable Medical
Device
(Includes sensor
interface, processor,
user I/O, and power
management)
Bluetooth®
Wireless Data
Transmission
Sub-1GHz ISM RF
USB Controller
Wired Data
Transmission
TI has considerable experience designing connectivity solutions for
interoperability and coexistence.
Medical Applications Guide
141
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Overview (Continued)
Low-Power Wireless (ISM)
TI offers a wide selection of cost-
effective, low-power RF solutions for
both proprietary and standard-based
wireless applications. The portfolio
includes RF transceivers, RF transmitters and Systems-on-Chip for shortrange applications in the sub-1GHz
and 2.4GHz frequency bands.
To choose the right radio for specific
applications, designers need to determine at what frequency band to operate. TI’s radios operate in either the global
2.4GHz or the sub-1GHz Industrial
Scientific Medical (ISM) bands. The
2.4GHz is available for license-free
operation in most countries around the
world and enables the same solution to
be sold in several markets without
software/hardware alterations.
The ISM bands below sub-1GHz have
limitations that vary from region to
region, but their strength is a better
range than 2.4GHz with the same output power and current consumption. In addition, there is less interference
present in the band. Since different
sub-1GHz bands are used in different
markets, custom solutions become a
necessity.
The trade-off between the need for
interoperability and the cost of software design and development will, to
a large extent, determine the choice of
software platform. TI’s software portfolio ranges from proprietary solutions
with a high degree of design freedom
and low complexity to fully interoperable ZigBee® solutions.
➔ Medical USB Platform
TI offers a Continua-certified USB
hardware-software platform that
implements the Personal Healthcare
Device Class (PHDC) along with IEEE
11073. As personal healthcare devices
become more ubiquitous, companies
are developing products with connectivity that allow data to be exchanged
easily. PHDC (Personal Healthcare
Device Class), which is part of the
USB standard, is designed for portable
medical and wellness devices to be
able to send measurements to USB
hosts such as personal computers,
cell phones, etc. The Continua Health
Alliance has released guidelines for
interoperability between various types
of devices implementing the USB
standard. Texas Instruments offers a
hardware-software platform that has
been certified by the Continua Health
Alliance after having passed a rigorous
testing procedure. Customers can use
Medical Applications Guide
the software stacks of this platform to
reduce development time for devices
that will comply with the medical industry standards such as the Continua
Health Alliance. These stacks are available for use on TI’s industry-leading,
ultra-low-power MSP430™ MCUs.
For more information on the Continua Health Alliance, visit http://www.continuaalliance.org.
For more information on the medical USB platform, visit http://www.ti.com/usbplatform.
Medical Application
Device Specializations
IEEE 11073-104xx
Data Exchange Protocol
IEEE 11073-20601
USB API
PHDC
CDC
HID
MSD
Physical Layer
142
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Wired Solutions
USB-to-Serial Bridge
TUSB3410
Get samples, datasheets, application reports and evaluation modules at: www.ti.com/sc/device/TUSB3410
Key Features
• USB full-speed (12Mbps) compliant
• Integrated 8052 microcontroller with
16K bytes of RAM that can be
loaded from the host or external
memory via an I2C bus
• Integrated, enhanced UART features
include:
• Programmable software/hardware
flow control
• Automatic RS-485 bus transceiver
control, with and without echo
• Software-selectable baud rate
from 50 to 921.6K baud
• Built-in, 2-channel DMA controller
for USB/UART bulk I/O
• TUSB3410UARTPDK product development kit can jump-start USB-toserial development
Applications
• Handheld meters
• Health metrics/monitors
• Legacy-free PC COM port
replacement
Medical Applications Guide
TUSB3410 and TUSBWINVCP software provides an easy way to move serialbased legacy devices to a fast, flexible USB interface by bridging a USB port and
an enhanced UART serial port. The TUSB3410 contains all of the logic needed to
communicate with the host computer using the USB bus. The TUSBWINVCP software package enables the TUSB3410 to act as a virtual COM port and appear as
legacy COM ports on the back of older model computers. This enables the use of
existing devices and application software without making any changes.
3.6V
EEPROM
Parameter
Storage
V-REG
5V
Host PC
USB
*Several new MSP430™ families
such as F552x have integrated USB
capabilities where an external USB
controller is not required
SDA
SCL
TUSB3410
USB Controller
12MHz
MSP430*
7 3728MHz
TUSB3410/MSP430™ implementation block diagram.
143
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Wireless Interface, RFID and Tag-it™
Radio Frequency Identification
(RFID)
TI’s high-frequency RFID product family consists of 13.56MHz high-
frequency (HF) transponders and low-
power RFID readers that are compliant
with ISO/IEC 15693 and ISO/IEC
18000-3 global open standards. Typical RFID implementations include
asset tracking, access control, blood
bag tracking, medical supply tracking,
patient/staff authentication, pharma­
ceutical authentication, medical imaging,
product authentication, remote digital
healthcare management applications and many non-medical related
applications.
open standards. These products are
available in six different antenna shapes
with frequency offset for integration
into paper, PVC or other substrates
manufactured with TI’s patented lasertuning process to provide consistent
read performance. Prior to delivery, the
transponders undergo complete functional and para­metric testing to provide
the high quality customers have come
to expect.
• Data retention time (at +55°C): >10 years
Tag-it HF-I Family
• 256-bit user memory, 8 x 32-bit
• Password-protected write command
• Command to disable IC functionality
• FastSID
Key Features
• User and factory lock per block
• Application Family Identifier (AFI)
Standard
• 256-bit user memory, 8 x 32-bit
• FastSID
Pro
Product Specifications
• Supported standards: ISO/IEC
15693-2, -3; ISO/IEC 18000-3
• Recommended operating frequency:
13.56MHz
• Factory programmed read-only numbers: 64-bit
• Typical programming cycles (at
+25°C): 100,000
Tag-it HF-I Transponder Inlays
TI’s Tag-it HF-I family of transponder
inlays consists of 13.56MHz HF transponders that are compliant with ISO/
IEC 15693 and ISO/IEC 18000-3 global
Plus
• 2Kbit user memory, 64 x 32 6-bit
• Data Storage Format Identifier
(DSFID)
• Combined inventory read block
Tag-it™ HF-I Plus Inlay Shapes
Part Number
Available Memory
Antenna Size (mm)
Foil Pitch (mm)
Frequency Offset for
Lamination Material
Delivery
RI-I11-112A-03
RI-I11-112B-03
RI-I02-112A-03
RI-I02-112B-03
RI-I03-112A-03
RI-I15-112B-03
RI-I16-112A-03
RI-I17-112A-03
2K bits organized in 64 x 32-bit blocks
45 x 45
45 x 45
45 x 76
45 x 76
22.5 x 38
34 x 65
θ 24.2
θ 32.5
50.8 + 0.1/
–0.4 (2 in)
50.8 + 0.1/
–0.4 (2 in)
96 + 0.1/
–0.4 (~3.78 in)
96 + 0.1/
–0.4 (~3.78 in)
58 +0.1/
–0.4 (~1.89 in)
101.6 +0.1/
–0.4 (4 in)
50.8 +0.1/
–0.4 (2 in)
50.8 +0.1/
–0.4 (2 in)
Paper
PVC
Paper
PVC
Paper/PVC
PVC
Paper/PVC
Paper/PVC
Single tape row with 48mm foil width wound on cardboard reel
Tag-it™ HF-I Pro Transponder Inlays
Part Number
Available Memory
Foil Width (mm)
Antenna Size (mm)
Foil Pitch (mm)
Frequency Offset for
Lamination Material
Delivery
RI-I11-114A-S1
RI-I11-114B-S1
RI-I02-114A-S1
RI-I02-114B-S1
RI-I03-114-S1
RI-I16-114-S1
RI-I17-114-S1
256 bits organized in 8 x 32-bit blocks
48mm ±0.5mm
45 x 45
45 x 45
45 x 76
45 x 76
22.5 x 38
θ 24.2
θ 32.5
50.8 +0.1/
–0.4 (2 in)
50.8 +0.1/
–0.4 (2 in)
96 +0.1/
–0.4 (~3.78 in)
96 +0.1/
–0.4 (~3.78 in)
48 +0.1/
–0.4 (~1.89 in)
50.8 +0.1/
–0.4 (2 in)
50.8 +0.1/
–0.4 (2 in)
Paper
PVC
Paper
PVC
Paper/PVC
Paper/PVC
Paper/PVC
RI-I02-114A-01
RI-I02-114B-01
RI-I03-114-01
RI-I16-114-01
RI-I17-114-01
Single row tape wound on cardboard reel
Tag-it™ HF-I Standard Transponder Inlays
Part Number
Available Memory
Foil Width (mm)
Antenna Size (mm)
Foil Pitch (mm)
Frequency Offset for
Lamination Material
Delivery
RI-I11-114A-01
RI-I11-114B-01
256 bits organized in 8 x 32-bit blocks
48mm ±0.5mm
45 x 45
45 x 45
45 x 76
45 x 76
22.5 x 38
θ 24.2
θ 32.5
50.8 +0.1/
–0.4 (2 in)
50.8 +0.1/
–0.4 (2 in)
96 +0.1/
–0.4 (~3.78 in)
96 +0.1/
–0.4 (~3.78 in)
48 +0.1/
–0.4 (~1.89 in)
50.8 +0.1/
–0.4 (2 in)
50.8 +0.1/
–0.4 (2 in)
Paper
PVC
Paper
PVC
Paper/PVC
Paper/PVC
Paper/PVC
Single row tape wound on cardboard reel
Medical Applications Guide
144
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Wireless Interface, RFID and Tag-it™
Low-Power, Multi-Standard HF RFID Readers
TRF7960,TRF7961
Get samples and datasheets at: www.ti.com/sc/device/TRF7960 or www.ti.com/sc/device/TRF7961
Key Features
• Supports ISO14443A/B, ISO15693
and Tag-it
• High level of integration reduces total
cost, BOM and board area
• Completely integrated protocol
handling
• Separate, internal high-PSRR
LDOs for analog, digital and PA
sections provide noise isolation for
superior read range and reliability
• Integrated LDO regulator output
for MCU
• Single Xtal system with available
output clock for MCU
• Eleven user-accessible and programmable registers
• Low-power device with wide operating voltage range: 2.7V to 5.5V
Complementing the Tag-it™ HF-I family of transponder inlays is TRF7960, a highly
integrated analog front end and data framing system for any 13.56MHz RFID
reader system. Built-in programming options make TRF7960 useful for a wide
range of applications, both in proximity and vicinity RFID systems. A high level of
integration, excellent performance, miniature size and multiple low-power modes
allow TRF7960 to be used for battery-power-constrained medical applications.
• Programmable output power:
100mW or 200mW
• Parallel 8-bit or serial 4-pin SPI
interface with 12-byte FIFO
• Seven user-selectable, ultra-low-power modes
• Power down: <1µA
• Standby: 120mA (typical)
• Active: 10mA (RX only)
• Available MSP430™ software
libraries
• Packaging: Ultra-small, 5 x 5mm,
32-pin QFN
Tag
Antenna
13.56 MHz
TRF796x
Timing
System
Supply
Regulators
Protocol Decoders/
Encoders and
Framing
Dual Rx
LC
Network
MSP430
Control
Registers
Tx AFE
Rx Gain
and Filters
SPI
Parallel
Interface
SPI/Parallel
Interface
CPU
CLK_SYS
Digitizer
VDD_X
XIN
DVCC
12 Byte FIFO
Functional block diagram.
Medical Applications Guide
145
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Wireless Interface, RFID and Tag-it™
Low-Power, Multi-Standard HF RFID Readers (Continued)
TRF7960,TRF7961
Get samples and datasheets at: www.ti.com/sc/device/TRF7960 or www.ti.com/sc/device/TRF7961
Applications
• Medical
• Patient and staff authentication
• Pharmaceutical authentication
• Product authentication and
calibration
• Remote digital healthcare
management
• Asset tracking
• Access control
• Contactless payments
• Prepaid eMetering
• eGovernment
TRF7960 Evaluation Module
(EVM)
Tag-it™ smart labels bring affordable RFID technology to a wide
range of new applications.
The TRF7960 evaluation tool
allows for quicker and simplified
system design. The TRF7960
multiple-­protocol RFID transceiver
incorporates an analog front end,
protocol handling, framing, error
checking and multiple integrated
voltage regulators with other features that allow the reader to be
customized/configured to the end
application.
TRF7960 EVM features include:
• Fully functional RFID reader with
on-board and (optional) offboard antenna capabilities
• GUI that support the
ISO14443A, ISO14443B,
ISO15693 and Tag-it commands
• Separate LEDs that indicate tag
detection—operates in standalone mode without GUI
Medical Applications Guide
Tag-it™ HF-I family transponder inlays are available in a variety of package
options, including square, circular and rectangular (regular and mini).
146
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Low-Power RF Products
Integrated Multi-Channel RF Transceiver
CC1101
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/CC1101
Key Features
• Sub-1GHz FSK/GFSK/MSK/ASK/
OOK RF transceiver
• 1.2 to 500Kbaud data rate
• Low power, low system cost
• Sleep current: –200nA
• 90μs PLL lock time: –240μs from
sleep to RX/TX
• On-chip support for sync word
detection, address check, flexible
packet length and automatic CRC
checking
• Separate 64-byte RX and TX data
FIFOs enable burst-mode data
transmission
• Suitable for systems targeting compliance with EN 300, 200 (Europe)
and FCC CFR Part 15 (U.S.)
Need longer RF range? Try the
CC2590/CC1190 2.4GHz and sub 1GHzRF
range extender for low-power RF ICs.
The CC1101 is a highly integrated, multi-channel RF transceiver designed for
low-power wireless applications in the 315/433/868/915MHz ISM bands. The
CC1101 is an upgrade of the CC1100 transceiver with improvements for spurious
response, close-in phase noise, input saturation level, output power ramping and
extended frequency range.
Applications
• Wireless alarm and security systems
• AMR
• Industrial monitoring MSP430
and control
CPU
• Home and building automation
26MHz
32kHz
SPI
USART/
USC/
USI
CC1101/
CC2500
I/O
LC
Network
RAM
DMA
Chemical
Sensors
Self-Test
and Bias
Mux
Amp
ADC
LCD
Intl
GDOn
DAC
Example application block diagram – wireless blood gas analyzer.
Sub-1GHz System-on-Chip RF Solution
CC1110/F8/F16/F32
Get samples and datasheets at: www.ti.com/sc/device/CC1110
Key Features
• Low current consumption
• High-performance RF transceiver
core (same as in the CC1100)
• 8- to14-bit ADC with up to eight
inputs
• 21 general I/O pins
• Real-time clock and several timers
• 8/16/32KB in-system programmable
Flash
• 1/2/4KB RAM
• Packaging: 6 x 6mm QLP-36
See also the CC2510 and CC2511—
2.4GHz, System-on-Chip RF solutions.
Need longer RF range? Try the
CC2590/CC2591 2.4GHz RF range
extender for low-power RF ICs.
Visit: www.ti.com/cc2591
Medical Applications Guide
The CC1110 is a low-cost System-on-Chip (SoC) IC designed for low-power
and low-voltage wireless communication applications. The CC1110 combines
the excellent perform­ance of the CC1100 RF transceiver with an industry-standard
enhanced MCU, 8/16/32KB of in-system programmable Flash memory, 1/2/4KB of
RAM and many other useful peripherals. Because of several advanced low-power
operating modes, the CC1110 is designed for systems where very low power consumption is required.
AES 128-Bit
Encryption Engine
Keypad, Analog
Sensor, LCD Display
with SPI or UART
Interface, I2S
Compatible Audio
Codec or Other
Peripherals to
be Controlled
by a MUC
8-14 Bits
8 Channel
ADC +
Temp. Sensor
2x USART
I2S
21 Digital I/O
(Including ADC)
4 Timers: 3x 8-Bit,
1x 16-Bit with ∆Σ Mode
Antenna
8051 Core with
Integrated
Memory
Management
and DMA
1/2/4kb
RAM
RF Front-End
Identical to
C1100
8/16/32kb
FLASH
General-purpose medical device using CC1110. Supports secure
RF link with embedded 128-bit AES hardware encryption.
147
Texas Instruments 2010
Connectivity Solutions for Medical
➔ ZigBee® / Bluetooth® Low Energy
ZigBee® and Bluetooth® Low
Energy Solutions for Medical
Applications
The world is going wireless and medical
applications are no exception. More and
more medical devices, especially patient
monitoring, can benefit from wireless
technology. ZigBee and Bluetooth Low
Energy can be utilized in the consumer
health, wellness, and medical space across a range of applications. • Z-Tool (debug tool)
• Development kits: CC2520DK,
CC2530DK and CC2530ZDK
• TIMAC: IEEE 802.15.4 Medium Access
Control (MAC) software stack for TI
IEEE 802.15.4 transceivers and SoCs
TI is part of the Continua Health Alliance
and an active contributor to the evolvement of ZigBee and Bluetooth Low
Energy, the wireless standards for medical applications selected by the alliance.
Applications
• Patient monitoring
• Hospital equipment tracking
TI’s low-power RF portfolio of high-performance RF ICs offers robust and costeffective wireless connectivity solutions
for a variety of medical devices.
With the use of ZigBee wireless sensors,
the patients can move around in the hospital, or even in their homes, and the sensors
will still monitor and send critical health
data to the hospital or doctor. Being independent of a patient’s exact geographical
location has a positive impact on both the
patient and the hospital. The ZigBee standard enables companies to have a simple,
reliable, low-cost and low-power standardbased wireless platform for their application development.
Bluetooth Low-Energy solutions are
designed for low-cost, low-power and
short range connectivity. The technology
enables direct communication to cellular
For more information, visit:
www.ti.com/zigbee
IEEE 802.15.4/ZigBee compliant RF ICs
Bluetooth Low Energy IC
• CC2520: Second-generation 2.4GHz
ZigBee/IEEE 802.15.4 RF transceiver
• CC2530/31: True System-on-Chip
(SoC) with integrated microcontroller
• CC2530ZNP: ZigBee network processor that communicates with any MCU
via an SPI or UART interface
• Reference designs downloadable for
all RF ICs
• CC2540: 2.4 GHz system-on-chip for
Bluetooth low energy applications
• Available in the third quarter of 2010
Bluetooth Low Energy Development Tools
• CC2540DK-MINI
• CC2540DK
ZigBee Software and Development Tools
Applications
• Consumer Health / Medical
• Bluetooth Low Energy Systems
• Wireless Sensor Systems
• Z-Stack™: ZigBee and ZigBee Pro
compliant protocol stack. TI offers this
For more information, visit: www.ti.com/bluetoothlowenergy
Backlight
Patient Monitoring
and Data Upload
Display
Connectivity
Touch
Screen
Control
LVDS
SerDes
WiFi/Zigbee
PC, Monitor & Keyboard
full ZigBee stack free of charge. Z-Stack
supports over-the air download (OAD) for
firmware upgrades in the field.
phones, laptops and other Bluetooth
enabled devices such as sports and
fitness watches, GPS / handhelds, and
other personal monitoring devices. Bluetooth
S-Video
TV
Clock
Low Power Wireless
Ethernet
Audio/Video
Codec
Analog Front End
HS USB
Transceiver
(ECG, Pulse Oximetry,
Blood Pressure, Other)
Processor
Integrated ECG
Front End
Keypad
Control
Audio
Feedback
USB
Protection
Keypad
Power
Manager
USB Port
LED
Drivers
Inst AMP
Battery
Charger
Power Source
Buffer AMP
ADC
Human Body
Medical Applications Guide
Level
Shifter
Isolation
Product Availability and Design Disclaimer – The system block
diagram depicted above and the devices recommended are
designed in this manner as a reference. Please contact your
local TI sales office or distributor for system design specifics
and product availability.
On/Off
MS/MMC/
SD/SDIO
Card
Core and I/O
Supply
Gas
Gauge
System
Power
AC/DC
Supply
Battery
LEGEND
Plug
Main Power Supply
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Multi-parameter patient monitor
system block diagram.
148
Texas Instruments 2010
Resources
➔ Enhanced Products/Die and Wafer Sales Solutions
Enhanced Products
TI’s Enhanced Product (EP) line offers
design flexibility while still meeting HiRel
and Medical standards for operating
environments where high reliability and
long service life are a requirement. The EP
line offering can benefit avionic, defense,
aerospace, medical, and industrial
designers as well as designers in other
rugged operating environments and
long service life application fields. TI’s
Enhanced Product line is a commercial
of-the-shelf (COTS) solution with the following key benefits:
• Fabrication/assembly controlled baseline
• Extended product change notification (PCN)
• Extended temperature performance
(typically -55°C to +125°C)
• Standalone data sheet
• Qualification pedigree
• Product traceability
• Long life cycles
TI’s EP products are guaranteed to
perform to data sheet specifications in
environments that require extended temperatures (typically -55°C to +125°C). To
ensure that a device exhibits the highest
quality and reliability possible for targeted
TI Die/Wafer Solutions
Texas Instruments offers bare die/wafer
solutions for applications that require
higher levels of integration to reduce
board space. TI provides a wide range
of products in bare die and wafer form. A variety of testing and qualification
options are available based on product maturity and complexity, as well
as customer requirements. Typical
screening options include DC probe or AC/DC probe at temperature.
Medical Applications Guide
applications, TI performs the following qualification procedures before the
device is released:
• All EP devices undergo extensive
requalification
• Qualification data is reviewed and
audited for accuracy and compliance
• Reliability and electromigration monitoring is performed at maximum recommended operating conditions in
the targeted package.
• Certified test programs & test hardware
• Electrical characterization is performed
across specified temperature range
• Package performance is confirmed
over extended temperatures (some
mold compounds are not suitable for extended temperatures).
• Nickel/palladium/gold/lead finish eliminates “tin whisker” reliability issues
• Knowledgeable expertise in medical
related ISO requirements (ISO13485
and ISO14971)
• Certificate of compliance to datasheet
electrical specifications
• Available in military (–55°C/125°C), industrial (–40°C/85°C), commercial (0°C/70°C)
and custom temperature ranges
Enhanced Products
Expected from TI’s EP line:
• Qualification summary report
• Access to leading-edge commercial
technology
• Commitment to the Industrial, Medical,
Avionic and Defense markets
• Customer-driven portfolio
• Enhanced obsolescence management
In addition TI will evaluate the release of other TI’s catalog devices in an
EP versions based on customer
requirements.
Get more information about TI’s
enhanced products at: www.ti.com/ep
TI offers three categories of die
screening:
Typical processing and capabilities
include:
• Commercial wafers and die
• Mount and bond diagrams
• Probed die – 55°C to +210C° or special temp
• Shipping: Tape and reel, waffle
packs, custom trays, Gel-Pak®
• Sidewall and visual inspections
• Standard TI wafer fabrication
• Known Good Die (KGD)
• Stand alone datasheet and
warranted over temperature
• Customer defined qualification
• QML Class Q (MIL-STD)
• QML Class V (Space)
• Additional options available
149
For more information regarding TI’s Die and Wafer offerings, visit
www.ti.com/hirel or email:
[email protected]
Texas Instruments 2010
Resources
➔ TI Design Tools
Below you’ll find a sampling of the design tools TI offers to simplify your design process. To access any of the following application
reports, type the URL www-s.ti.com/sc/techlit/litnumber and replace litnumber with the number in the Lit Number column.
For a complete list of analog application reports, visit: analog.ti.com/appnotes
For a complete list of DSP application reports, visit: www.dspvillage.ti.com/tools
Title
Lit Number
Amplifiers
Single-Supply Operation of Isolation Amplifiers
SBOA004
Very Low Cost Analog Isolation with Power
SBOA013
Boost Instrument Amp CMR with Common-Mode Driven Supplies
SBOA014
DC Motor Speed Controller: Control a DC Motor without Tachometer Feedback
SBOA043
PWM Power Driver Modulation Schemes
SLOA092
Thermo-Electric Cooler Control Using a TMS320F2812 DSP and a DRV592 Power Amplifier
SPRA873
Isolation Amps Hike Accuracy and Reliability
SBOA064
Make a –10V to +10V Adjustable Precision Voltage Source
SBOA052
±200V Difference Amplifier with Common-Mode Voltage Monitor
SBOA005
AC Coupling Instrumentation and Difference Amplifiers
SBOA003
Extending the Common-Mode Range of Difference Amplifiers
SBOA008
Level Shifting Signals with Differential Amplifiers
SBOA038
Photodiode Monitoring with Op Amps
SBOA035
Single-Supply Operation of Isolation Amplifiers
SBOA004
Precision IA Swings Rail-to-Rail on Single 5V Supply
SBOA033
Pressure Transducer to ADC Application
SLOA056
Buffer Op Amp to ADC Circuit Collection
SLOA098
Amplifiers and Bits: An Introduction to Selecting Amplifiers for Data Converters
SLOA035B
Diode-Connected FET Protects Op Amps
SBOA058
Signal Conditioning Piezoelectric Sensors
SLOA033A
Diode-Based Temperature Measurement
SBOA019
Single-Supply, Low-Power Measurements of Bridge Networks
SBOA018
Thermistor Temperature Transducer to ADC Application
SLOA052
Signal Conditioning Wheatstone Resistive Bridge Sensors
SLOA034
Low-Power Signal Conditioning for a Pressure Sensor
SLAA034
Interfacing the MSP430 and TMP100 Temperature Sensor
SLAA151
Data Converters
Configuring I2S to Generate BCLK from Codec Devices & WCLK from McBSP Port
SLAA413
Interfacing the ADS8361 to the TMS320F2812 DSP
SLAA167
Interfacing the TLC2552 and TLV2542 to the MSP430F149
SLAA168
MSC1210 In-Application Flash Programming
SBAA087
Pressure Transducer to ADC Application
SLOA056
Measuring Temperature with the ADS1216, ADS1217, or ADS1218
SBAA073
SPI-Based Data Acquisition/Monitor Using the TLC2551 Serial ADC
SLAA108A
Implementing a Direct Thermocouple Interface with MSP430x4xx and ADS1240
SLAA125A
Using the ADS7846 Touch-Screen Controller with the Intel SA-1110 StrongArm Processor
SBAA070
Complete Temp Data Acquisition System from a Single +5V Supply
SBAA050
Interfacing the ADS1210 with an 8xC51 Microcontroller
SBAA010
Programming Tricks for Higher Conversion Speeds Utilizing Delta Sigma Converters
SBAA005
Retrieving Data from the DDC112
SBAA026
Selecting an ADC
SBAA004
Synchronization of External Analog Multiplexers with the
SBAA013
The DDC112’s Test Mode
SBAA025
Understanding the DDC112’s Continuous and Non-Continuous Modes
SBAA024
Thermistor Temperature Transducer to ADC Application
SLOA052
Medical Applications Guide
150
Texas Instruments 2010
Resources
➔ TI Design Tools (Continued)
Title
Lit Number
Low-Power Signal Conditioning for a Pressure Sensor
SLAA034
Data Converters (Continued)
Signal Acquisition and Conditioning with Low Supply Voltages
SLAA018
An Optical Amplifier Pump Laser Reference Design Based on the AMC7820
SBAA072
Processors/Microcontrollers
Programming a Flash-Based MSP430 Using the JTAG Interface
SLAA149
Mixing C and Assembler with the MSP430
SLAA140
Implementing an Ultra-Low-Power Keypad Interface with the MSP430
SLAA139
Heart Rate Monitor and EKG Monitor Using the MSP430FG439
SLAA280
A Single-Chip Pulsoximeter Design Using the MSP430
SLAA274
MSP430 Interface to CC1100/2500 Code Library
SLAS325
Choosing an Ultra-Low-Power MCU
SLAA207
ECG, Pulse Oximeter, Digital Stethoscope Development Kits based on C5505 Processor
SPRT523
MSP430 USB Connectivity Using TUSB3410
SLAA276A
MSP430 Flash Memory Characteristics
SLAA334
Wave Digital Filtering Using the MSP430
SLAA331
Implementing a Real-Time Clock on the MSP430
SLAA076A
Interface
CAN
A System Evaluation of CAN Transceivers
SLLA109
Introduction to the Controller Area Network
SLOA101
Using CAN Arbitration for Electrical Layer Testing
SLLA123
RS-485
Interface Circuits for TIA/EIA-485 (RS-485)
SLLA036B
422 and 485 Standards Overview and System Configurations
SLLA070C
RS-485 for E-Meter Applications
SLLA112
TIA/EIA-485 and M-LVDS, Power and Speed Comparison
SLLA106
USB
VIDs, PIDs and Firmware: Design Decisions When Using TI USB Device Controllers
SLLA154
USB/Serial Applications Using TUSB3410/5052 and the VCP Software
SLLA170
CardBus
PCI1520 Implementation Guide
SCPA033
LVDS
LVDS Design Notes
SLLA014A
Reducing EMI with LVDS
SLLA030C
Performance of LVDS Over Cables
SLLA053B
M-LVDS
Introduction to M-LVDS
SLLA108
M-LVDS Speed Versus Distance
SLLA119
Serdes
Gigabit Transmission Across Cables
SLLA091
Power Controllers
DC Brush Motor Control using the TPIC2101
SLIT110
Power Management
Technical Review of Low Dropout Voltage Regulator Operation and Performance
SLVA072
ESR, Stability, and the LDO Regulator
SLVA115
Extending the Input Voltage Range of an LDO Regulator
SLVA119
High Current LDO Linear Regulators (UCCx81-ADJ, UCCx82-ADJ, UCCx83-ADJ, UCCx85-ADJ)
SLUA256
PowerPAD™ Thermally Enhanced Package
SLMA002
Medical Applications Guide
151
Texas Instruments 2010
TI Worldwide Technical Support
Asia
Internet
TI Semiconductor Product Information Center Home Page
support.ti.com
TI E2ETM Community Home Page
e2e.ti.com
Product Information Centers
Americas
Brazil
Mexico
Phone
Phone
Phone
Fax
Internet/Email
+1(972) 644-5580
0800-891-2616
0800-670-7544
+1(972) 927-6377
support.ti.com/sc/pic/americas.htm
Europe, Middle East, and Africa
Phone
European Free Call
00800-ASK-TEXAS
(00800 275 83927)
International
+49 (0) 8161 80 2121
Russian Support
+7 (4) 95 98 10 701
Note: The European Free Call (Toll Free) number is not active in all ­countries.
If you have technical difficulty calling the free call number, please use the
­international number above.
Fax
+(49) (0) 8161 80 2045
Internet
support.ti.com/sc/pic/euro.htm
Japan
Phone
Fax
Internet/Email
Domestic
International
Domestic
International
Domestic
0120-92-3326
+81-3-3344-5317
0120-81-0036
support.ti.com/sc/pic/japan.htm
www.tij.co.jp/pic
The platform bar, E2E Community, Auto-Track, C28x, C55x, C674x, C2000, C5000, C6000, C64x+,
DaVinci, Delfino, DLP Discovery, DLP Pico, EasyScale, eXpressDSP, Impedance Track, Microamplifier,
MSP430, Nanostar, OMAP, Piccolo, PowerPAD, Sitara, SmartGain, SmartReflex, Tag-it,
TMS320,TMS320C24x, TMS320C28x, TMS320C5000, TMS320C54x, TMS320C55x, TMS320C6000,
TMS320C64x+, TMS320DM64x+, TurboTrans, VelociTI, Z-Stack and Z-Accel are trademarks of Texas
Instruments and DLP and Stellaris are a registered trademark of Texas Instruments. The Bluetooth word
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their respective owners
Phone
International
+91-80-41381665
Domestic
Toll-Free Number
Australia
1-800-999-084
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800-820-8682
Hong Kong
800-96-5941
India
1-800-425-7888
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001-803-8861-1006
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080-551-2804
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0800-446-934
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800-886-1028
Taiwan
0800-006800
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001-800-886-0010
Fax
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Email
[email protected]
[email protected]
Internet
support.ti.com/sc/pic/asia.htm
Important Notice: The products and services of Texas Instruments
Incorporated and its subsidiaries described herein are sold subject to TI’s
standard terms and conditions of sale. Customers are advised to obtain
the most current and complete information about TI products and services
before placing orders. TI assumes no liability for applications assistance,
customer’s applications or product designs, software performance, or
infringement of patents. The publication of information regarding any
other company’s products or services does not constitute TI’s approval,
warranty or endorsement thereof.
B121709
Cert no. SW-COC-001530
© 2010 Texas Instruments Incorporated. Printed in U.S.A. by Jarvis Press, Dallas, TX
SLYB108E
IMPORTANT NOTICE
Texas Instruments Incorporated and its subsidiaries (TI) reserve the right to make corrections, modifications, enhancements, improvements,
and other changes to its products and services at any time and to discontinue any product or service without notice. Customers should
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Following are URLs where you can obtain information on other Texas Instruments products and application solutions:
Products
Applications
Amplifiers
amplifier.ti.com
Audio
www.ti.com/audio
Data Converters
dataconverter.ti.com
Automotive
www.ti.com/automotive
DLP® Products
www.dlp.com
Communications and
Telecom
www.ti.com/communications
DSP
dsp.ti.com
Computers and
Peripherals
www.ti.com/computers
Clocks and Timers
www.ti.com/clocks
Consumer Electronics
www.ti.com/consumer-apps
Interface
interface.ti.com
Energy
www.ti.com/energy
Logic
logic.ti.com
Industrial
www.ti.com/industrial
Power Mgmt
power.ti.com
Medical
www.ti.com/medical
Microcontrollers
microcontroller.ti.com
Security
www.ti.com/security
RFID
www.ti-rfid.com
Space, Avionics &
Defense
www.ti.com/space-avionics-defense
RF/IF and ZigBee® Solutions www.ti.com/lprf
Video and Imaging
www.ti.com/video
Wireless
www.ti.com/wireless-apps
Mailing Address: Texas Instruments, Post Office Box 655303, Dallas, Texas 75265
Copyright © 2010, Texas Instruments Incorporated
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