Diagnostic, Patient Monitoring and Therapy

Diagnostic, Patient Monitoring and Therapy
Diagnostic, Patient
Monitoring and Therapy
Applications Guide
Digital Stethoscopes
Patient Monitoring
ECG and EEG
Pulse Oximetry
Ventilation
CPAP
Dialysis Machine
Infusion Pump
AED
Connectivity Solutions
www.ti.com/medical
2010
Diagnostic, Patient Monitoring and Therapy Applications Guide
➔ Table of Contents
Disclaimer
TI products are not authorized for use
in safety-critical applications (such as
life support) where a failure of the TI
product would reasonably be expected
to cause severe personal injury or
death, unless TI and the customer have
executed an agreement specifically
governing such use. The customer
shall fully indemnify TI and its repre­sent­
atives against any damages arising out
of the unauthorized use of TI products
in such safety-critical applications. The
customer shall ensure that it has all
necessary expertise in the safety and
regulatory ramifications of its applications and the customer shall be solely
responsible for compliance with all legal,
regulatory and safety-related requirements concerning its products and
any use of TI products in customer’s
applications, notwithstanding any
applications-related information or
support that may be provided by TI.
Diagnostic, Patient Monitoring and Therapy
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Digital Stethoscopes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Patient Monitoring . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Electrocardiogram (ECG)/Portable ECG and
Electroencephalogram (EEG) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
Pulse Oximeter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
Ventilator . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Continuous Positive Airway Pressure (CPAP) . . . . . . . . . . . . . . . . . . . . . . . . 41
Dialysis Machine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
Infusion Pump . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
Automated External Defibrillator (AED) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54
Connectivity Solutions for Medical
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Medical USB Platform . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Wired Solutions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Wireless Interface, RFID and Tag-it™ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Low-Power RF Products . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
ZigBee® / Bluetooth® Low Energy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
59
60
61
62
65
66
Resources
Enhanced Products/Die and Wafer Sales Solutions . . . . . . . . . . . . . . . . . . . 67
TI Design Tools . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68
TI Worldwide Technical Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
TI’s Medical Applications
Guides available for
individual download:
• Consumer
Medical
• Diagnostic, Patient
Monitoring and Therapy
• Medical
• Medical
Imaging
Instruments
Visit:
www.ti.com/medicalguides
Diagnostic, Patient Monitoring and Therapy Applications Guide
2
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Overview
Trends in Medical Diagnostic, Patient
Monitoring and Therapy equipment
include portability, connectivity,
flexibility and system intelligence.
Medical equipment such as digital
stethoscopes, patient monitoring,
ECG, EEG, and pulse oximetry
have all become more portable
through improvements in battery and
battery management technologies,
and the proliferation of wireless
communications technologies like
Bluetooth® and ZigBee®. The addition
of features like touch screen control
and audio feedback have taken away
the complicated mix of knobs and dials
and replaced them with menu-driven
displays and user prompts. On top of
this the precision of the sensor signal
chain combined with the processing
power of today’s embedded
processors have paved the way for
these instruments to not only notice the
smallest perturbation from normality in
a signal, these devices can collect and
process trends against large databases
and even suggest a course of action.
These improvements in reliability,
battery storage capability and usability
have also taken the Automated
External Defibrillators (AEDs) from
equipment only found in medical
facilities and emergency vehicles
to tools deployed in many schools,
businesses and other public areas.
Low power processing allows an AED
to sleep for long time periods, only
waking up to run diagnostics, and
then quickly get to full operation when
needed. Such as the intelligence to
guide the user safely through its use
and the ability to sense if the pads are
incorrectly placed on the patient have
truly helped drive the proliferation of
these devices.
By combining the advances in
monitoring capabilities with those seen
in motor control, power management,
and control systems, applications such
as ventilation/CPAP, dialysis, and
infusion pumps have been made
smaller, safer and less expensive.
This trend has made it practical for
CPAP systems and Infusion pumps to
be placed in the home, and dialysis
therapy to move from a hospital-only
application to a doctor's office.
Connectivity for portable medical applications has become critical as consumers and caregivers are requiring data
to move from medical devices to data
hubs such as computers and mobile
phones. TI is a promoting member
of the Continua Health Alliance and
now offers the first
Continua-certified
USB platform for
Agent Devices.
See page 60 for
more information.
For more information on TI’s offering
for Diagnostic, Patient Monitoring
and Therapy, please visit
www.ti.com/patientmonitoring
➔ Digital Stethoscopes
The main elements of a digital stethoscope (see page 4) are the sensor
unit that captures the heart and lung
sounds (also known as auscultations),
along with auscultation digitization and
digital processing for noise reduction,
filtering and amplification. Algorithms
for heart rate detection and heart
defect detection may also be included.
Power and battery management are
key in this ultra-portable diagnostic
tool. Design considerations include
ultra-low-power consumption and high
efficiency, both of which are driven
by the need for extended battery life.
The design must also incorporate high
precision with a fast response time
to allow quick determination of the
patient’s health status.
The need to record auscultations calls
for cabled or wireless interfaces that
transmit the auscultations. To enable
ease-of-use, features like touch-screen
control and display backlighting are
essential. Adding these features without significantly increasing power
consumption is a huge challenge.
Diagnostic, Patient Monitoring and Therapy Applications Guide
3
TI’s portfolio of processors, instrumentation and buffer amplifiers,
power and battery management,
audio codecs, and wired and
wireless interface devices
provides the ideal tool box for
digital stethoscope applications.
The common core sub-systems of
a digital stethoscope are the analog front-end/sensor interface and
codec, low-power processor, and
data storage and transmission.
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Digital Stethoscopes
Analog Front-End/Sensor
Interface and Codec
Low-Power Processor
Memory
Power
FLASH/
EPROM
SDRAM
Processors that are able to execute the
digital stethoscope’s signal processing functions, such as noise reduction,
algorithms for heart rate detection and
heart defect detection, while maintaining a very low constant current draw
from the battery, are a good fit.
Auscultation signal input is amplified
and digitized by the audio codec.
Auscultations signals after being digitized are subjected to signal processing. They are then converted to analog
and sent to the stethoscope earpiece.
The ability to control memory interfacing and peripheral devices is also helpful. Processors that manage the digital
display and keyed functions allow
auscultation waveforms to be displayed
and manipulated without additional
components.
Display
*Heart Rate Detection
*Heart Defects Detection
- Murmur
- Regurgitation
- Septal Defects
- Mitral Valve Prolapse
- Stenosis
Level Shift
Acoustic Amplifier
Tube
Keypad
MMC/
SD
Headphone
Amp
REF
Electret Condenser
Microphone
Logic
I2S
Control
2
Signals I C
Audio
Codec
Pre-Amp
Data
EMIF/I2C GPIO
LCD
Touch Screen
Control
Backlight
Processor
Clock
Common Interfaces
Bluetooth
Core
and I/O
Power
USB
USB
ESD
USB Port
LEGEND
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Lithium
Battery
Protection
Gas
Gauge
Battery
Charger
System
Power
Optional Battery Management
(Needed for Recharging)
AC/DC
Adapter
Battery
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Digital stethoscope
system
block
diagram.
Product Availability
and Design
Disclaimer
- The system block diagram depicted above and the devices recommended are
designed in this manner as a reference. Please contact your local TI sales office or distributor for system design specifics
and product availability.
Diagnostic, Patient Monitoring and Therapy Applications Guide
4
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Digital Stethoscopes
Power-Efficient Fixed-Point DSP
TMS320C5515
Get samples, datasheets, tools and application reports at: www.ti.com/sc/device/TMS320C5515
Key Features
• High-performance/low-power,
C55x™ fixed-point DSP
• 16.67/13.33/10/8.33ns instruction
cycle time
• 60, 75, 100, 120MHz clock rate
• 320K bytes on-chip RAM
• 16-/8-bit external memory interface
(EMIF)
• Two multi-media card/secure
digital I/Fs
• Serial-port I/F (SPI) with four
chip-selects
• Four inter-IC sound (I2S bus™)
• USB 2.0 full- and high-speed device
• LCD bridge with asynchronous
interface
• Tightly-coupled FFT hardware
accelerator
• 10-bit 4-input SAR ADC
The TMS320C5515 is a member of TI’s TMS320C5000™ fixed-point digital signal
processor (DSP) product family and is designed for low-power applications.
The TMS320C5515 fixed-point DSP is based on the TMS320C55x™ DSP generation CPU processor core. The C55x™ DSP architecture achieves high performance
and low power through increased parallelism and total focus on power savings.
The CPU supports an internal bus structure that is composed of one program bus,
one 32-bit data read bus and two 16-bit data read buses, two 16-bit data write
buses, and additional buses dedicated to peripheral and DMA activity.
These buses provide the ability to perform up to four 16-bit data reads and two
16-bit data writes in a single cycle.
DSP System
Input
Clock(s)
JTAG Interface
C55x™ DSP CPU
PLL/Clock
Generator
FFT Hardware
Accelerator
Power
Management
64 KB DARAM
Pin
Multiplexing
256 KB SARAM
128 KB ROM
Switched Central Resource (SCR)
Applications
• Portable ultrasound
• Automatic external defibrillator (AED)
• Electrocardiogram (ECG)
• Digital stethoscopes
• Cochlear implants
Peripherals
Interconnect
DMA
(x4)
Program/Data Storage
Serial Interfaces
I2 S
(x4)
I2 C
SPI
App-Spec
Display
Connectivity
10-Bit
SAR
ADC
LCD
Bridge
USB 2.0
PHY (HS)
[DEVICE]
NAND, NOR,
SRAM, mSDRAM
UART
MMC/SD
(x2)
System
RTC
GP Timer
(x2)
GP Timer
or WD
LDOs
TMS320C5515 DSP block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
5
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Digital Stethoscopes
Digital Stethoscope (DS) Analog Front End Module for the C5515 DS Medical Development Kit
TMDXMDKDS3254
Get samples, datasheets and evaluation modules at: www.ti.com/tmdxmdkds3254
Key Features
• DS AFE module key components
• TLV320AIC3254: flexible, lowpower, low-voltage stereo audio
codec with programmable inputs
and outputs
• OPA335: 0.5µV/°C, CMOS
zero-drift operational amplifier
• DS MDK system features
•Based on industry’s lowest power
DSP processor – TMS320C5515
•Audio output in three selectable
modes:
- Bell mode (20Hz to 220Hz)
- Diaphragm mode (50Hz to 600Hz)
- Extended Range (20Hz to 2000Hz)
•Three channel input options, two
condensor and one contact
microphone
•Volume control and mute
•Real time display of heart signal on
onboard LCD and PC
•Store and playback option on PC
side
To reduce the time to market for medical device companies, TI has launched a
set of medical application development tools with complete signal chain designs
and software for electrocardiograms, digital stethoscopes, and pulse oximeter
products. Each of the three medical development kits (MDKs) is comprised by
purchasing an analog front-end (AFE) module with specific circuitry design optimized for each end product plus a TMS320C5515 DSP evaluation module (EVM)
based on the industry’s lowest power DSP—TMS320C5515. MDKs provide a
great evaluation platform to help medical device manufacturers focus on product
differentiation, like algorithm development and feature enhancement.
The TMDXMDKDS3254 Digital Stethoscope (DS) Analog Front End (AFE) module
consists of the DS AFE module, a processor board (C5515 DSP evaluation module),
a set of collateral and C5515-based application sample code to implement the
DS application. The DS MDK delivers a complete signal chain solution to enable
developers to build an entire DS system quickly for evaluation and get to
production faster.
Applications
• Digital stethoscope devices
• Patient monitoring
TMDXMDKDS3254 EVM.
Diagnostic, Patient Monitoring and Therapy Applications Guide
6
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Digital Stethoscopes
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
Laptop-like performance at handheld power levels
OMAP-L137
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
TMS320C5505
Low-Power DSP
TMS320C5515
*Page 5
TMS320VC5503
Power-Efficient
DSP
Low-Power DSP
16-/8-bit EMIF, 320K bytes on-chip RAM, USB 2.0
full- and high-speed device
16-/8-bit external memory interface, 320K bytes on-chip
RAM, USB 2.0 full- and high-speed device
Up to 200MHz, dual MAC, 16-bit HPI, 3 McBSP
Highly integrated, dual-core solution drives low system
cost and maximum flexibility for connectivity, GUI and
high-level OS options. Extends product battery life
by providing greater than 60% power reduction over
existing solutions in the market.
High-performance, low-power
TMS320VC5507
Low-Power DSP
TMS320VC5509A
Low-Power DSP
Up to 200MHz, dual MAC, 128KB RAM/64KB ROM,
USB 2.0 full speed, 10-bit ADC
Up to 200MHz, dual MAC, 256KB RAM/64KB ROM,
USB 2.0 full speed, MMC/SD, 10-bit ADC
Designed for low-power applications; low-power,
high-performance
Power efficient, low-cost DSP, C55x™ code
compatibility
Power efficient, C55x code compatibility
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L138
C550x DSP
C550x DSP
Power efficient, large on-chip memory, rich
peripheral set allows for various portable
connectivity; C55x code compatibility
C550x DSP
Longer battery life, better audio quality, lower
system cost
TLV320AIC3204 (pin to
pin without miniDSP)
Data Converters
TLV320DAC32
Low-Power
Audio DAC
Low-Power
Audio Codec
Low-Power
Audio Codec
Low-Power
Audio Codec
Low-power stereo DAC, 4 outputs, HP/speaker amplifier,
3D effects
Low-power stereo codec, 6 inputs, 6 outputs, headphone
amp, enhanced digital effects
Low-power stereo codec, 6 inputs, 6 outputs, headphone
amp, enhanced digital effects
Very-low power, single supply, miniDSP for audio
processing
DRV134/5
Line Driver/
Receiver
0.0005% at f = 1kHz distortion, 17Vrms into 600Ω output
swing, ±5.2mA IQ, ±4.5V to ±18V supply
Balanced output pair, low distortion
INA134, INA137
INA134/2134
Line Driver/
Receiver
0.0005% at f = 1kHz distortion, 90dB CMRR, 0dB (1V/V)
fixed gain, ±2.9mA IQ, ±4V to ±18V supply
Excellent AC specifications, low distortion
INA137, OPA1632
INA137/2137
Line Driver/
Receiver
Differential line receiver, low distortion
INA134, DRV134
OPA134/2134
Audio Amp
0.0005% at f = 1kHz distortion, 90dB CMRR, 6dB fixed
gain, ±2.9mA IQ, ±4V to ±18V supply
—
0.00008% ultra-low distortion, 8nV/√Hz noise, 8MHz BW,
120dB open-loop gain, ±2.5V to ±18V supply
True FET-input stage, low distortion, low noise
OPA211, OPA604
OPA141
Precision Op Amp
Common mode voltage range includes GND
OPA827, OPA132
OPA209
Precision Op Amp
Unity gain stable, RRO, wide supply range, low
power
OPA211
Precision Op Amp
10MHz, 6.5nV/√Hz, ±4.5V to ±18V, 1.8mA typical, FET
input: IB = 20pA max
—
2.2nV/√Hz at 1kHz, ±4.5V to 18V supply, 18MHz, 2.5mA
quiescent current (typ)
—
1.1nV/√Hz noise at 1kHz, ±2.25V to ±18V supply, 80MHz
BW
Unity gain stable, RRO, wide supply range
OPA227
OPA378
Low Noise
Precision Op Amp
0.1µV/°C Vos drift, 125µA, 900kHz, 0.4μVPP (0.1Hz to
10Hz) 0.4µ Vpp (0.1Hz to 10Hz), 0.9MHz
Lowest noise, power, price, precision zero-drift
option
OPA330, OPA333
OPA827
Precision JFET Op
Amp
4nV/√Hz noise at 1kHz, ±4V to ±18V supply, 15pA (typ)
input bias current, 22MHz BW
High precision, low noise, low input bias, wide
supply range
OPA177, OPA627,
THS4521
Low Power FDA
1.14mA quiescent current (typ), 4.6nV/√Hz voltage noise
Very low power, low noise enables high accuracy
ESD Solution
Low capacitance, 2 channels, ±15kV ESD-protection
array for high-speed data interfaces
IEC 61000-4-2 system level (level 4) ESD protection;
low input capacitance in space-saving packages
TLV320AIC3104
TLV320AIC3106
TLV320AIC3254
Amplifiers
Interface
TPD2E001
New products are listed in bold red. Preview products are listed in bold blue.
view more system block diagram compatible products, visit www.ti.com/medical
To
Diagnostic, Patient Monitoring and Therapy Applications Guide
SN65220
7
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Digital Stethoscopes
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management
bq29312A
Li-Ion Battery
Protection IC
Provides under- and overvoltage, overcurrent, shortcircuit and overtemperature protection
Provides primary safety protection for cells
bq29330
Battery Safety
Battery pack full-protection analog front end
Provides individual cell voltages and battery
voltage to battery-management host
bq29410/1/2
Li-Ion Battery
Protection IC
Provides overvoltage protection for Li-Ion and poly cells
Prevents false triggers during dynamic operating
conditions
bq2000
Battery
Management
Multi-chemistry charger
One charge for both Li-Ion and NiCad/NiMH cells
bq24100
Battery Charge
Management
Switch mode, 1100kHz switching frequency, >2A charge
current
d/dt, min current primary charge termination
method
TPS5130
DC/DC Converters
Triple synchronous buck controller with LDO
Provides 4 output voltages in 1 package
TPS61070
DC/DC Converters
600mA switch low voltage in boost
Can generate 5V rail from 1-, 2- or 3-cell alkaline
or 1-cell Li-Ion
TPS61097-33
Boost Converter
with Bypass Switch
Highly efficient, operates down to 0.3V; bypass switch; 5nA
shutdown current; SOT-23
Super efficient boost, works over entire battery range,
low quiescent current, integrate the bypass switch,
small package
TPS61120
DC/DC Converters
Dual switcher boost and LDO
Compact 2-voltage solution
TPS62202
DC/DC Converters
300mA synchronous
Ultra-small battery-powered solutions
TPS22902
Load Switch with
Controller Turn-On
Low on resistance, controlled turn-on, ultra small 0.64mm2
package, quick output discharge
Ultra-small, fully integrated solution
TPS65020
Linear Charge
Management
6-channel power management IC with 3 DC/DCs, 3 LDOs,
I2C interface and dynamic voltage scaling
Provides complete solution in one package
TPS65023
Linear Charge
Management
6-channel power management IC with 3 DC/DCs, 3 LDOs,
I2C interface and DVS, optimized for DaVinci™ DSPs
Provides complete DaVinci solution in one package
TPS65800
Linear Charge
Management
6-channel power management IC with 2 DC/DCs, 7 LDOs,
I2C interface and dynamic voltage scaling
Complete power management solution in one
package
TPS74401
LDO
Single-output LDO, 3.0A, adjustable (0.8V to 3.3V), fast
transient response, programmable soft start
Adjust the voltage ramp rate for your processor
requirements
TPS79601
LDO
1A low-dropout regulator with high PSRR
Low-noise LDO stable with 1µF ceramic capacitor
TPS796xx
TPS79630
LDO
1A low-dropout regulator with high PSRR
Low-noise LDO stable with 1µF ceramic capacitor
TPS796xx
Digital
Stethoscope (DS)
Analog Front End
Module for the
C5515 DS Medical
Development Kit
Audio output in three selectable modes; 3 channel input
options; volume control and mute; real time display of
heart signal on onboard LCD and PC; store and playback
option on PC side
Based on industry’s lowest power DSP processor –
TMS320C5515
TPS22901, TPS22922,
TPS22924C, TPS22960
Toolkits
TMDXMDKDS3254
*Page 6
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
8
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Patient Monitoring
A variety of portable, single and multipleparameter monitors have emerged
over the last few years that measure
blood pressure, glucose levels, pulse,
tidal carbon dioxide and other biometric values. Patient monitors are
portable, flexible devices that can be
adapted to a wide range of clinical
applications and support various wired
and wireless interfaces.
Key Features
The most important features of today’s
patient monitors are mobility, ease-ofuse and effortless patient data transfer.
Mobility includes portability as well
as the ability to interface with other
medical devices such as anesthesia
machines and defibrillators. Ease-ofuse can be achieved with touch-screen
displays and multi-level, menu-driven
profiles that can be configured for the
environment and the patient’s vital
statistics.
Data transfer across everything from
wireless to RS-232 must be possible. While hospitals may support a
specific infrastructure throughout all
areas, ambulance, home and other
An ongoing need to minimize healthcare costs is creating a move toward
patient treatment and monitoring
outside of the hospital. This shift is
placing an emphasis on remote patient
monitoring and telemedicine solutions
that enable providers to treat patients
in highly populated, rural and remote
areas in emerging economies.
Backlight
Patient Monitoring
and Data Upload
Touch
Screen
Control
Display
Connectivity
LVDS
SerDes
WiFi/Zigbee
PC, Monitor & Keyboard
environments often require support for
different protocols.
Bluetooth
S-Video
TV
Clock
Low Power Wireless
Ethernet
Audio/Video
Codec
Analog Front End
HS USB
Transceiver
(ECG, Pulse Oximetry,
Blood Pressure, Other)
Processor
Integrated ECG
Front End
Keypad
Control
Audio
Feedback
USB
Protection
Keypad
Power
Manager
USB Port
LED
Drivers
Inst AMP
Battery
Charger
Power Source
Buffer AMP
ADC
Human Body
On/Off
Level
Shifter
Isolation
MS/MMC/
SD/SDIO
Card
Core and I/O
Supply
Gas
Gauge
System
Power
AC/DC
Supply
Battery
LEGEND
Plug
Main Power Supply
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Multi-parameter patient monitor system block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
9
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Patient Monitoring
TI’s OMAP™/Davinci™
Technology Solution
The challenges involved in implementing patient treatment and monitoring
equipment are similar to systems
implementation challenges faced by
the cellular phone industry. TI’s
OMAP™ technology, with embedded
ARM® and DSP processor cores,
directly addresses these challenges.
TI has an extensive portfolio of analog
front-end solutions for essential signal
conditioning. The OMAP 3 processor enables digital signal processing,
measurements and analytics needed to
monitor patient condition. TI’s powerful
ARM processor runs a high-level OS
(HLOS) that makes adding multi-modal
monitoring easy and provides extensive user interface and system control.
Detecting abnormal conditions and
communicating to a central server are
essential to providing timely and
on-demand healthcare. OMAP 3 has
an innovative peripheral set that supports connectivity options such as
Bluetooth® technology, WiFi®, ZigBee®
and other emerging standards.
Applications Processor
OMAP35x
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/omap35x
Key Features
• ARM® Cortex-A8 core
• TI’s DaVinci™ C64x+™ DSP core
• 2D/3D graphics accelerator
• OpenGL® ES 2.0 compatible
graphics engine
• Neon™ coprocessor
• Scalable platform:
• OMAP3503 (ARM-only version)
• OMAP3515 (ARM and 2D/3D
graphics accelerator)
• OMAP3525 (ARM and DSP)
• OMAP3530 (ARM, DSP and 2D/3D
graphics accelerator)
• Optimized laptop-like performance
at handheld power levels in a single
chip
• TI’s SmartReflex™ power and
perform­ance management
• 65nm CMOS
The OMAP35x generation of processors includes four distinct single-chip
­processors with a variety of combinations of the ARM® Cortex-A8 core, multimedia-rich peripherals, OpenGL® ES 2.0 compatible graphics engine, video
accelerators and the high-performing TMS320C64x+™ DSP core. Offering laptoplike perform­ance at handheld power levels, the OMAP35x provides users with a
highly flexible platform capable of creating a powerful user interface experience,
with additional signal processing for application implementation. In addition, TI’s
SmartReflex™ power and performance management technologies reduce overall
power consump­tion and optimize performance, allowing users to develop innovative, low-power applications. The processor provides a range of interfaces for analog front ends, power and battery monitoring, displays, keypads and touch-screen
solutions. Also, support for various connectivity options such as USB, Wi-Fi®,
ZigBee®, Ethernet and other emerging standards is integrated into the processor.
®
ARM
®
CORTEX -A8
CPU
Applications
• Multiparameter patient monitors
• Portable ultrasound
• Automatic external defibrillator (AED)
• Electrocardiogram (ECG)
Display Subsystem
C64x+™ DSP and
Video Accelerators
(3525/3530 only)
LCD
10-Bit DAC
Con- Video
troller Enc 10-Bit DAC
2D/3D
Graphics
(3515/3530 only)
Camera I/F
Image
Pipe
Parallel I/F
L3/L4 Interconnect
Peripherals
Connectivity
System
USB 2.0 HS
USB
OTG
Host
Controller Controller ×2
Timers
GP ×12
WDT ×2
Serial Interfaces
McBSP
×5
2
IC
×3
UART
×2
UART
w/IrDA
McSPI
×4
Program/Data Storage
HDQ/1-Wire
SDRC
GPMC
MMC/
SD/
SDIO
×3
OMAP35x processor.
Diagnostic, Patient Monitoring and Therapy Applications Guide
10
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Patient Monitoring
Stellaris®
LM3S3xxx
Get samples, datasheets, evaluation modules at: www.ti.com/stellaris
Key Features
• Up to 256kB integrated flash and
96kB SRAM
• Integrated ethernet MAC+PHY
• USB host/device/on-the-go
• Free license for complete and rich
software libraries (StellarisWare®)
Applications
• Patient monitoring
• Home health hubs
Designed for high-end microcontroller applications, the Stellaris family provides the
entry into the industry’s strongest ecosystem, with code compatibility ranging from $1
to 1GHz.
• Superior integration saves up to $3.28 in system cost
• Over 160 Stellaris family members to choose from
• Real MCU GPIOs—all can generate interrupts, are 5V-tolerant, and have programmable drive strength and slew rate control
• Advanced communication capabilities, including 10/100 Ethernet MAC/PHY, USB and USB OTG, CAN controllers, and extended peripheral interfaces
• Sophisticated motion control support in hardware and software
• Both analog comparators and ADC functionality provide on-chip system options to balance hardware and software performance
• Development is easy with the royalty-free StellarisWare software
32
JTAG
256 KB Flash
NVIC
ARM
Cortex™-M3
SWD
100 MHz
32
96 KB SRAM
32
ROM
Clocks, Reset
System Contol
3 UARTs
Systick Timer
10/100 Ethernet
MAC + PHY
IEEE 1538
2 Watchdog Timers
USB Full Speed
GPIOs
Host / Device / OTG
3 CAN
32ch DMA
2 I2C
EPI
I2S
Precision
Oscillator
2 Quadrature
Encoder Inputs
8 PWM Outputs
Timer
Comparators
R
Y
C
32
Battery-Backed
Hibernate
LDO Voltage
Regulator
3 Analog
Comparators
PWM
PWM
Generator Interrupt
2x 10-bit ADC
Each 8 channel
1 Msps
Dead-Band
Generator
Temp Sensor
ANALOG
MOTION CONTROL
4 Timer/PWM/CCP
Each 32-bit or 2x16-bit
SYSTEM
SERIAL INTERFACES
2 SSI/SPI
Stellaris family block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
11
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Patient Monitoring
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
AM3517
OMAP3530
*Page 10
OMAP-L137
Applications
Processor
Applications
Processor
Low-Power
Applications
Processor
Stellaris®
LM3S3xxx *Page 11
Microcontroller
ARM® Cortex-A8, graphics acelerators, Ethernet, CAN
High performance at handheld power levels
AM3505
ARM Cortex-A8, C64x+™, graphics accelerator,
video accelerators
300MHz ARM9™ w/MMU + 300MHz C674x™
floating-point DSP core, rich peripheral set including
10/100 Ethernet MAC, LCD controller, USB 2.0 HS
OTG, USB 1.1 full speed, SPI and MMC/SD
ARM® Cortex-M3, up to 256KB flash, up to 64kB
RAM, USB host/device
Laptop-like performance at handheld power levels
OMAP3503, OMAP3515,
OMAP3525
OMAP-L138
16-bit, 860SPS, 4 SE, 2 diff input, PGA, MUX,
comparator, VREF
24-bit, 8 PGA, 8 ADC, plus RLD and RESP
Smallest 16-bit ADC, 2.0 x 1.5 x .04 mm leadless WFN
pkg; reduces system size and componenent count
Complete front end, reduction in power and size,
increase reliability
Small size, low power, serial interface
ADS1113/4,
ADS1013/14/15
ADS1294, ADS1296,
ADS1198, ADS1258
ADS7886
Intelleigent system power management and self
monitoring
Low power, small package, and excellent
performance
Full on-chip data acquisition system
ADS7828, ADS7823
Low power, small package, and wide supply range
ADS8317
Longer battery life, better audio quality, lower cost
TLV320DAC3101
Longer battery life, better audio quality, lower
system cost
TLV320AIC3204 (pin2pin
without miniDSP)
±250μV (max) input offset, 83dB CMRR, 0.175mA
(typ) IQ
—
60µV offset, 0.7 µV/°C drift, 8nV/√(Hz) noise
Precision low power, ±1.35V to ±8V supply
INA2126, INA122
Low noise, low drift, wide supply, wide BW
INA118, INA129
25μV (max) offset, 50nV/°C drift, 50μA (typ) Iq
Best offset/noise combination, supply down to 1.8V,
low power
High speed, wide input and output voltage swing,
excellent DC accuracy
Zero drift, high precision, low power, EMI input
INA321, INA326
®
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
USB, 10-bit ADC, temperature sensor
Data Converters
ADS1115
Delta-Sigma ADC
ADS1298
ECG/EEG AFE
ADS7866
SAR ADC
ADS7924
Low-Power SAR
ADC
SAR ADC
ADS7953
ADS8201
ADS8326
Micropower SAR
ADC
SAR ADC
TLV320AIC3104
Audio Codec
TLV320DAC3120
Low-Power Audio
DAC
Low-Power Audio
Codec
Audio DAC
TLV320AIC3254
TLV320DAC32
12-bit, 200kSPS, 71dB SNR, ±1.5 LSB (max) INL,
1.6V to 3.6V supply
12-bit, 100kSPS, 4 channel, ≤1µA power down
current, I2C interface, QFN package
12-bit, 16-channel, 1MSPS, SPI interface with
threshold alarms, QFN package
8 channel, 12-bit, 100kSPS, 1.32mW power
consumption at 100kSPS
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max)
INL, SE input
Low-power stereo codec, 6 inputs, 6 outputs,
headphone amp, enhanced digital effects
Mono DAC with 2.5W mono Class-D speaker
amplifier; miniDSP for audio processing
Very-low power, single supply, miniDSP for audio
processing
Low-power stereo DAC, 4 outputs, HP/speaker
amplifier, 3D effects
ADS7952, ADS7956,
ADS7957/60/61
ADS7870
Amplifiers
INA126
OPA2822
Instrumentation
Amp
Instrumentation
Amp
Instrumentation
Amp
High-Speed Amp
OPA333
Precision Op Amp
OPA376
Precision Op Amp
OPA378
Low Noise
Precision Op Amp
High-Speed Amp
INA128
INA333
OPA695
TPA2006D1
TPA2010D1
TPA2013D1
TPA3007D1
TPA6205A1
TPA6211A1
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Class-AB Audio Amp
Class-AB Audio Amp
—
Dual, 2nV/√Hz noise, 240MHz GBWP, 90mA output,
4.8mA/ch IQ, +5V to +12V supply
1.8V min supply, 0.017mA/ch (max), 10μV offset
(max), 0.05 μV/°C drift (max)
7.5nV/√Hz noise, 760μA(typ)/ch Iq, 5μV (typ) offset,
input EMI filter, RRO
0.1µV/°C Vos drift, 125µA, 900kHz, 0.4μVPP (0.1Hz to
10Hz) 0.4µ Vpp (0.1Hz to 10Hz), 0.9MHz
1.4GHz BW (G = +2), 4300V/µs slew rate, 129mW
power, ±4.2V output voltage swing
1.45W mono, filter-free Class D, 1.8V shutdown
OPA2690, OPA842
OPA335, OPA378,
OPA330
OPA340, OPA337,
OPA364
OPA330, OPA333
Low noise, low power, low input bias
Lowest noise, power, price, precision zero-drift
option
Wide bandwidth, current feedback, low power, fast
signal conditioning
OPA847, OPA691
2.5W mono, fully differential, filter-free Class D, in
WCSP
2.7W constant output power, mono, Class D,
integrated boost converter
Mono, medium power, filter-free Class D
Loud audio, long battery life, small package size
TPA2031D1
Louder audio at low battery levels
TPA2014D1
1.25W mono, fully differential, Class AB, 1.8V shutdown
3.1W mono, fully differential, Class AB
Loud audio, low cost
Loud audio
TPA6204A1
Wake-on-radio functionality; integrated packet handling
with 64B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2 to 500kbps; extremely fast PLL turn-on/hop time
Programmable data rate from 1.2 to 500 kBaud, fast
startup time (0.3µs), low current consumption
Ideal for low-power systems; any low-end MCU can
be used; backwards compatible with existing systems;
suitable for fast frequency hopping systems
Fast development time and low system cost, flexible
optimization of range vs. power, small solution size
CC2500
RF ICs
RF Transceivers
CC1101
Sub-1GHz RF
Transceiver
CC1150
Sub-1GHz
Transmitter
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
New products are listed in bold red. Preview products are listed in bold blue.
12
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Patient Monitoring
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
RF ICs (Continued)
RF Transceivers (Continued)
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended
temperature range; AES-128 security module
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal
for industrial applications; no external processor
needed for secure communication
CC2530
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital
radio processor technology.
MCU, USB 2.0, Flash and RAM in one package;
four flexible power modes for reduced power
consumption; includes CC1101 transceiver frequency
synthesizer; built-in AES-128 encryption coprocessor
Second Gen.
System-on-Chip
Solution for 2.4GHz
IEEE 802.15.4/
RF4CE/ZigBee®
2.4 GHz Bluetooth®
Low Energy
compliant RF
System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
Excellent RX sensitivity, low power, easy to use
development tools
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
RF design System-on-Chip for quick time to
market. Provides a robust and complete ZigBee
USB dongle or firmware-upgradable network node
RF Systems-on-Chip
CC2560
CC1110/11
CC2530/31
CC2540
WL1271
WL1273
Excellent link budget enabling long range
applications without external frontend, receiver
sensitivity, selectivity and blocking performance
RF design System-on-Chip for quick time to
market. Provides a robust and complete ZigBee
USB dongle or firmware-upgradable network node
Single-chip 802.11b/g/n WLAN and Bluetooth®
solution using TI’s digital radio processor technology
using a single antenna.
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
Fast-to-market Bluetooth® low energy compliant solution
CC2510, CC2511
CC2590/91, CC2530ZNP
CC2590/91, CC2530ZNP
Sophisticated low-power technology ideal for
battery operated solutions; coexistence features
enable simultaneous WLAN and Bluetooth®
operations; supports ANT+ standard.
WL1271
RF Network Processor
ZigBee® stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings; excellent selectivity and blocking
performance
Add CC2530ZNP and your system is ZigBee
enabled; ideal for battery operated systems;
excellent coexistence with Bluetooth® technology
and Wi-Fi.
Multi-chemistry charger
One charge for both Li-Ion and NiCad/NiMH cells
TPS43000
TPS5130
Battery
Management
Battery Charge
Management
DC/DC Controller
DC/DC Controller
Switch mode, 1100kHz switching frequency, >2A
charge current
2MHz operation
Triple synchronous buck controller and LDO
TPS61070
DC/DC Converter
Input voltage range of 0.9V to 5.5V
TPS61097-33
Boost Converter
with Bypass
Switch
DC/DC Converter
Highly efficient, operates down to 0.3 V; bypass switch;
5nA shutdown current; SOT-23
d/dt, min current primary charge termination
method
Allows smaller-value inductor and input cap
Four outputs in one package allows smaller power
solution
Allows 1-, 2- or 3-cell alkaline or 1-cell Li-lon
operation
Super efficient boost, works over entire battery range,
low quiescent current, integrates the bypass switch,
small package
Highly efficient dual-output operation for 1-cell
Li-Ion operation
Ultra-small, fully integrated solution
CC2530ZNP
Second
Generation
Z-StackTM
Network Processor
Power Management
bq2000/T
bq24100
TPS61120
TPS22902
TPS22946
TPS62420
TPS62202
TPS65020
TPS65023
TPS65800
Load Switch with
Controller Turn-On
Current Limited
Load Switch
DC/DC Converter
DC/DC Converter
Linear Charge
Management
Linear Charge
Management
TPS74401
Linear Charge
Management
LDO
TPS79601
TPS79630
LDO
LDO
Dual switch boost and 200mA LDO outputs
Low on resistance, controlled turn-on, ultra small
0.64mm2 package, quick output discharge
Configurable current limit, ultra-small package, 1µA
quiescent current at 1.8 V
Dual step-down buck converter with 1-pin easy scale
300mA synchronous buck in a SOT-23 package
6-channel power management IC with 3 DC/DCs,
3 LDOs, I2C interface and dynamic voltage scaling
6-channel power management IC with 3 DC/DCs,
3 LDOs, I2C interface and DVS, optimized for
DaVinci™ DSPs
6-channel power management IC with 2 DC/DCs,
7 LDOs, I2C interface and dynamic voltage scaling
Single-output LDO, 3.0A, adjustable (0.8V to 3.3V),
fast transient response, programmable soft start
1A low-dropout regulator with high PSRR
1A low-dropout regulator with high PSRR
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
Ultra-small, low quiescent current current limited
switch
Offers dynamic voltage scaling for power savings
Ultra-small implementation
Provides complete solution in one package
TPS65xxx
TPS22901, TPS22922,
TPS22924C, TPS22960
TPS22949, TPS22945
Provides complete DaVinci solution in one package
Complete power management solution in one
package
Adjust the voltage ramp rate for your processor
requirements
Low-noise LDO stable with 1µF ceramic capacitor
Low-noise LDO stable with 1µF ceramic capacitor
TPS796xx
TPS796xx
New products are listed in bold red. Preview products are listed in bold blue.
13
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Biophysical Monitoring Overview
wall contraction spreads electrical cur­
rents from the heart throughout the body.
The spreading electrical currents create
different potentials at different points
on the body, which can be sensed by
electrodes on the skin surface using
biological transducers made of metals
and salts. This electrical potential is an
AC signal with bandwidth of 0.05Hz to
100Hz, sometimes up to 1kHz. It is
generally around 1mV peak-to-peak in
the presence of much larger external
high frequency noise plus 50/60Hz
interference normal-mode (mixed
with the electrode signal) and common-mode voltages (common to all
electrode signals).
The human medical data acquisition
system, in particular the patient monitoring system, presents the challenge
to designers of measuring very small
electrical signals in the presence of
much larger common-mode voltages
and noise. Front-end amplifiers perform
the essential conditioning that complements downstream digital processing,
which in turn refines the measurement
and communicates with other systems.
Biophysical measurements include
electrical and mechanical signals for
general monitoring, diagnostic and
scientific purposes both in clinic and
non-clinic environments. Successfully
meeting the signal acquisition challenge requires system designers to
have knowledge of the signal source,
good design practice and ICs with
appropriate characteristics, features
and performance.
The common-mode is comprised of
two parts: 50Hz or 60Hz inter­ference
and DC electrode offset potential.
Other noise or higher frequencies
within the biophysical bandwidth come
from movement artifacts that change
the skin-electrode interface, muscle
contraction or electromyographic
Signal Acquisition Challenges
The action potential created by heart
spikes, respiration (which may be
rhythmic or sporadic), electro­magnetic
interference (EMI), and noise from other
electronic components that couple into
the input. Some of the noise can be
cancelled with a high-input-impedance
instrumentation amplifier (INA), like the
INA333 or INA118, which removes the
AC line noise common to both inputs
and amplifies the remaining unequal
signals present on the inputs; higher
INA common-mode rejection (CMR)
will result in greater rejection. Because
they originate at different points on the
body, the left-arm and right-arm ECG
signals are at different voltage levels
and are amplified by the INA. To further
reject 50 and 60Hz noise, an operational amplifier deriving common-mode
voltage is used to invert the commonmode signal and drive it back into
the patient through the right leg using
amplifier A2. Only a few microamps or
less are required to achieve significant
CMR improvement and stay within the
UL544 limit.
Backlight
LCD
Integrated Analog Front End
Input
Buffer
Touch Screen Control
Low Pass
(DC)
Filter
ADC
Mux
Wireless:
Zigbee
Bluetooth
Display
Driver
High
Pass
Filter
ADC
Summer
(resistive)
RLD
Temp Sense
Clock
Core
and I/O
Power
Low Noise Power
AC Line
Wired:
USB
RS232
Logic
Battery
Management
DDR
Power
FLASH/
EEPROM
Green
Mode
Control
DSP/OMAP
SDRAM
AC/DC
Supply
Signal
Processor
Level Shift
Human Body
Plug
Isolation
DS Converter
Ref
Memory
Power M
P
Managementt
LEGEND
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Three ECG electrodes connected to patient using CMOS components with 5V single supply. This circuit will
operate on a 3.3V supply.
Diagnostic, Patient Monitoring and Therapy Applications Guide
14
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Supply Voltage
Frequency Response
As in most other applications, the
system supply voltage in biophysical
monitoring continues the trend toward
low, single-supply levels. While bipolar
supplies are still used, 5V systems are
now common and trending to single
3.3V supplies. This trend presents a
significant challenge for the designer
faced with at least a 300mV DC electrode potential and emphasizes the
need for a precision signal-conditioning
solution.
Standard –3dB frequency bandwidth
for patient monitoring is 0.05Hz to 30Hz,
while diagnostic grade monitoring
requires 0.05Hz to 100Hz or more. The
analog front end must be AC coupled
to remove artifacts from the electrode
offset potential.
Operational Amplifier
Requirements
• Low noise in high gain
(Gain = 10 to 1000)
• Rail-to-rail output
• Very low offset and drift
Connectivity for ECG/EEG equipment
has become of interest as caregivers
require data to move from medical end
equipment to data hubs such as the
hospital/clinic IT infrastructure, computers or even mobile phones.
Instrumentation Amplifier
Requirements
• Stability in low gain (Gain = 1 to 10)
• High common-mode rejection
• Low input bias current (IB)
• Good swing to the output rail
• Very low offset and drift
Low-Power Applications Processor
OMAP-L137
Get datasheets, samples and technical documents at: www.ti.com/sc/device/omap-l137
The OMAP-L137 is a low-power applications processor based on an ARM926EJ-S™
and a C674x DSP core. It consumes significantly lower power than other members
of the TMS320C6000™ platform of DSPs. The OMAP-L137 enables OEMs and
ODMs to quickly bring to market devices featuring robust operating systems support, rich user interfaces, and high processing performance life through the maximum flexibility of a fully integrated mixed processor solution. The dual-core architecture of the OMAP-L137 provides benefits of both DSP and Reduced Instruction
Set Computer (RISC) technologies, incorporating a high-performance TMS320C674x
DSP core and an ARM926EJ-S core. The ARM926EJ-S is a 32-bit RISC processor core
that performs 32-bit or 16-bit instructions and processes 32-bit, 16-bit, or 8-bit data.
PRU Subsystem
DSP
Subsystem
ARM9
Subsystem
ARM
926EJ-S
CPU
2x PRU
4K+4K Prog
512+512 Data
C674x
DSP
Core
L1P 32K
L1D 32K
L2 256K
L1P 18K
L1D 18K
GPIOs
Key Features
• Dual core SoC
• 300MHz ARM926EJ-S™
RISC MPU
• 300MHz C674x VLIW DSP
• TMS320C674x fixed/floating-point
VLIW DSP core
• Enhanced direct-memory-access
controller 3 (EDMA3)
• 128K-byte RAM shared memory
• Two external memory interfaces
• Three configurable 16550 type UART
modules
• LCD controller
• Two serial peripheral interfaces (SPI)
• Multimedia card (MMC)/secure
digital (SD)
• Two master/slave inter-integrated
circuit
• One host-port interface (HPI)
• USB 1.1 OHCI (Host) with integrated
PHY (USB1)
LCD
LCD
Controller
Controller
128KB
RAM
Switched Central Resource (SCR) / EDMA
Peripherals
10/
100
EMAC
HPI
USB
1.1
USB2.0
Applications
• Medical measurement
• Industrial diagnostics
McASP
(3)
I2 C
(2)
MMC/SD
(1)
WD
Timer
(2)
eQEP
(2)
eCAP
(3)
PWM
(3)
External Memory Interfaces
Serial Interfaces
SPI
(2)
Control Timers
Connectivity
UART
(3)
EMIFB
SDRAM
32 -bit
EMIFA
NAND /
SDRAM
16-bit
OMAP-L137 block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
15
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Complete Analog Front End for ECG/EEG Applications
ADS1298
Get datasheets, samples and evaluation modules at: www.ti.com/sc/device/ADS1298
View the ADS1298 video at: http://e2e.ti.com/videos/m/analog/134732.aspx
Key Benefits
• Reduce components and board size
by 95%
• 1mW/channel reduces solution
power by 95%
• Single-chip solution increases system reliability and patient mobility
The eight-channel, 24-bit ADS1298 is the first in a family of fully integrated analog
front ends (AFEs) for patient monitoring, portable and high-end electrocardiogram
(ECG) and electroencephalogram (EEG). Succeeding four- and six-channel versions
and 16-bit versions offer designers a migration path to varying resolutions and
channel combinations for low-noise medical equipment. Examples include patient
monitors, rest and stress ECG, fetal monitoring, hospital and public access AEDs,
as well as sports and fitness monitors.
Key Features
• Eight low-noise PGAs
• Eight high-resolution, simultaneous
sampling ADCs
• Integrated amplifier for right-leg drive
• Integrated amplifiers for Wilson
Central Terminal (WCT) and
Goldberger Central Terminals (GCT)
• Digital pace detection capability
• Continuous lead-off detection
• Onboard oscillator and reference for
smaller footprint and low-power
applications
Applications
• ECG and EEG applications
ADS1298
REF
PGA1
ADC1
PGA8
ADC8
MUX
RLD
Wilson
Lead Off
Temperature
Test
Respiration
SPI
and
Control
Oscillator
Pace
Detect
ADS1298 block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
16
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Low-Noise, 900kHz, 50µV, RRIO Precision Op Amps
OPA378, OPA2378
Get samples and datasheets at: www.ti.com/sc/device/OPA378 or www.ti.com/sc/device/OPA2378
Key Features
Applications
• Low noise 0.1Hz to 10Hz: 0.4µVPP
• Low offset voltage: 15µV (typ)
• Quiescent current: 125µA (typ)
• Offset drift: 0.1µV/°C (typ)
• Single-supply operation
• Supply voltage: 2.2V to 5.5V
• EMI input filters and RRIO
• Packaging: SC70-5, SOT23-5
• Battery-powered instruments
• Medical instrumentation
• Temperature measurement
• Handheld test equipment
The OPA378 (single) and OPA2378
(dual) represent a new generation of
micro­power op amps featuring a combination of rail-to-rail I/O, low input
offset voltage (50µV (max)), low quiescent current and 90kHz bandwidth. It
has excellent PSRR which makes it an
ideal choice for applications that run
direct from batteries without regulation.
100nV/div
Voltage Noise (nV/√Hz)
100
10
1
Time (1s/div)
1
10
100
1k
Frequency (Hz)
10k
30k
OPA378: voltage noise spectral density
versus frequency.
OPA378: 0.1Hz to 10Hz noise.
Zerø-Drift, Low-Offset, Single-Supply Op Amps
OPA334, OPA335
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/OPA334
or www.ti.com/sc/device/OPA335
Key Features
• GBW: 2MHz
• Low offset voltage: 5µV (max)
• Zero drift: 0.05µV/°C (max)
• Quiescent current: 285µA
• EMI input filtered
• Shutdown available on OPA344
• Packaging: SOT23-5, SOT23-6,
SO-8, MSOP-10 (dual)
The OPA334 and OPA335 CMOS op amps use auto-zeroing techniques to
simultaneously provide very low offset voltage and near-zero drift over time and
tem­perature. These high-precision amps offer high input impedance and rail-to-rail
output swing.
VEX
R1
+5V
R
R
R
R
VOUT
OPA335
Applications
• Transducer applications, such as
pressure sensing
• Electronic weight scales
• Temperature measurement
R1
VREF
OPA335 –5V supply bridge amplifier for high CMRR
Diagnostic, Patient Monitoring and Therapy Applications Guide
17
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Precision, Rail-to-Rail I/O Instrumentation Amplifier
INA326
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/INA326
Key Features
• Low offset: 100µV (max)
• Low offset drift: 0.4µV/°C (max)
• Excellent long-term stability
• Very low 1/f noise
• Input common-mode range: 200mV
below negative rail to 100mV above
positive rail
• Wide output swing: Within 10mV of
rails
• Single supply: +2.7V to +5.5V
• Packaging: MSOP-8, MSOP-10
The INA326 is a precision instrumentation amplifier with rail-to-rail input and
output and with true single-supply operation it offers very low DC errors and
input common-mode ranges that extend beyond the positive and negative rails.
Excellent long-term stability and very low 1/f noise assure low offset voltage and
drift throughout the life of the product.
V+
Applications
• Medical instruments
• Multi-channel data acquisition
systems
• Low-level transducer amplifier for
bridges, load cells, thermocouples
• Wide dynamic range sensor
measurements
VIN–
2
1
R1
VIN+
V-
7
4
6
INA326
8
3
5
R2
VO
G = 2(R2/R1)
C2
INA326 functional block diagram.
4-/8-Channel, 16-Bit, Serial Output ADC for Portable Applications
ADS8331, ADS8332, ADS8341, ADS8342, ADS8343, ADS8344, ADS8345
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with ADS8331, ADS8332, ADS8341, ADS8342, ADS8343, ADS8344 or ADS8345)
Key Features
• Conversion rate: up to 100kHz
• 4-/8-channel single-ended or
2-channel differential input
• SINAD: 86dB
• Serial interface
• Single supply: 2.7V to 5V
• Packaging: SSOP-16
The ADS8341 is a 4-channel, 16-bit ADC with synchronous serial interface. Typical
power dissipation is 8mW at a 100kHz throughput rate and a +5V supply. The reference voltage can be varied between 500mV and VCC, providing a corresponding
input voltage range of 0V to VREF. It is tested down to 2.7V operation. The serial
interface also provides low-cost isolation for remote data acquisition.
SAR
DCLK
Applications
• Portable medical devices
• Test and measurement
• Data acquisition
CH1
CH2
CS
Comparator
CH0
Four
Channel
Multiplexer
CDAC
CH3
Serial
Interface
and
Control
SHDN
DIN
DOUT
BUSY
COM
VREF
ADS8341 functional block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
18
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Multi-Channel, 24-Bit, Delta-Sigma ADCs
ADS1271, ADS1274, ADS1278
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with ADS1271, ADS1274 or ADS1278)
Key Features
• Single-channel or simultaneously
measures 4/8 channels
• Up to 128kSPS data rate
• AC performance:
• Bandwidth: 62kHz
• SNR: 111dB (high-resolution mode)
• THD: –108dB THD
• DC accuracy:
• Offset drift: 0.8µV/°C
• Gain drift: 1.3ppm/°C
• Linear-phase digital filter
• SPI or frame-sync serial interface
• Analog supply: 5V
• Packaging: HTQFT-64 PowerPAD™
The ADS1271, ADS1274 and ADS1278 are single-, quad- and octal-channel ADCs,
respectively. These 24-bit, delta-sigma ADCs have data rates of up to 128kSPS,
allowing simultaneous sampling of all channels, and are offered in identical packages for drop-in expandability. The devices offer excellent DC and AC specifications for high-precision measurement applications. They provide a usable signal
bandwidth of up to 90 percent of the Nyquist rate with less than 0.005dB of ripple.
Four operating modes allow for optimization of speed, resolution and power.
VREFP VREFN
DVDD
SYNC/PDWN
MODE
Control
Logic
CLK
AINP
∆Σ
DRDY/FSYNC
SCLK
DOUT
DIN
FORMAT
Serial
Interface
Digital
Filter
Modulator
AINN
Applications
• Pressure sensors
• Patient monitoring
• Vibration/modal analysis
• Multi-channel data acquisition
• Acoustics/dynamic strain gauges
AVDD
AGND
DGND
ADS1271/4/8 functional block diagram.
Single, Dual and Quad Fully Differential Amplifiers
THS4521, THS4522, THS4524
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with THS4521, THS4522 or THS4524)
Key Features
• Low quiescent current: 1.14mA (typ)
• Power down capability: 20μA (typ)
• Input voltage noise: 4.6nV/√Hz
• Slew rate: 490V/µs
• Neg. rail-input and rail-to-rail output
• Power supply voltage:
+2.5V (±1.25V) to +5.5V (±2.75V)
• Packaging1: SO-8 and MSOP-8
(THS4521), TSSOP-16 (THS4522)
and TSSOP-38 (THS4524)
Applications
• Portable medical equipment
• Low power SAR and delta-sigma
ADC drivers
• Low power differential driver
• Low-power differential signal
conditioning
The THS4521(single), THS4522 (dual), and THS4524 (quad) are negative rail input, railto-rail output, fully differential amplifiers operating from a single +2.5V to +5.5V supply.
The low 1.14mA/channel quiescent current and power down capability to 20µA make it
a good choice for low power applications. The output common-mode control with low
offset and drift allows for dc-coupling in high accuracy data acquisition systems.
1k
1.5nF
5V
VIN+
49.9
1k
+
AINN1
–
THS4521
VIN–
–
1k
+
49.9
ADS1278: Ch1
2.2nF
AINP1
VCOM
VOCM
x1
0.1µF
1.5 nF
0.1µF
OPA2350
1k
THS4521 driving one channel of ADS1278 .
Diagnostic, Patient Monitoring and Therapy Applications Guide
19
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Electrocardiogram (ECG) Analog Front End Module for the C5515 ECG Medical Development Kit
TMDXMDKEK1258
Get samples, datasheets and evaluation modules at: www.ti.com/tmdxmdkek1258
Key Features
• ECG AFE module key components
• ADS1258: 16-channel, 24-bit
sigma delta analog-to-digital
converter (ADC)
• INA128: precision, low power
instrumentation amplifier
• PCA9535: remote 16-bit I2C and
SMBus low-power I/O expander
• TLV3404: nanopower open drain
output comparator
• REF5025: low-noise, very low drift
precision voltage reference
• ECG MDK system features
• Based on industry’s lowest power
DSP processor – TMS320C5515
• 12-lead ECG output using 10
electrode input
• 0.05Hz to 150Hz bandwidth
• Leads off detection
• Real-time 12-lead ECG waveform
display on EVM LCD, one lead at a
time
• Real-time 12-lead ECG waveform
display on PC, three leads at a
time
• Heart beat rate display
• Recording of ECG data, and offline
display option of recorded ECG
data
To reduce the time to market for medical device companies, TI has launched a
set of medical application development tools with complete signal chain designs
and software for electrocardiograms, digital stethoscopes, and pulse oximeter
products. Each of the three medical development kits (MDKs) is comprised by
purchasing an analog front-end (AFE) module with specific circuitry design optimized for each end product plus a TMS320C5515 DSP Evaluation Module (EVM)
based on the industry’s lowest power DSP – TMS320C5515. MDKs provide a
great evaluation platform to help medical device manufacturers focus on product
differentiation, like algorithm development and feature enhancement.
Applications
TMDXMDKEK1258 EVM .
The TMDXMDKEK1258 Electrocardiogram (ECG) Analog Front End (AFE) module
is part of the ECG medical development kit (MDK) that consists of the ECG AFE
module, a processor board (C5515 DSP evaluation module), a set of collateral and
C5515 based application sample code to implement the ECG application. The
ECG MDK delivers a complete signal chain solution to enable ECG developers to
build a complete ECG system quickly for evaluation and get to production faster.
• Portable ECG devices
• Patient monitoring
A new ECG Analog Front End module is also now available using the latest
ECG ADC – the ADS1298. The P/N for this is ADS1298ECGFE-PDK and it can
be used seamlessly with the C5515 EVM (TMDXEVM5515).
MDK ECG SW is freely available at:
http://code.google.com/p/c5505-ezdsp/
Diagnostic, Patient Monitoring and Therapy Applications Guide
20
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers
INA118
INA121
INA126
INA128
OPA277
INA326
*Page 18
INA333
OPA130
OPA333
OPA334/5
*Page 17
OPA336
OPA378
*Page 17
OPA2378
*Page 17
Instrumentation
Amp
Instrumentation
Amp
Instrumentation
Amp
Instrumentation
Amp
Op Amp
Instrumentation
Amp
Instrumentation
Amp
FET-Input
Amplifier
Precision Op Amp
Op Amp
110dB CMRR, 5nA (max) bias current, 50µV (max) offset
Wide BW at high gain, ±1.35V to ±18V supply
INA128, INA121
106dB CMRR, 4pA (max) bias current, 200µV (max) offset
Low input bias current
INA126
175µA/ch supply, 3µV/°C (max) drift, 250µV (max) offset
Precision low power, ±1.35V to ±18V supply
INA2126
120dB CMRR, 5nA (max) bias current, 50µV (max) offset
High CMRR, wide BW at high gain, ±2.25V to ±18V
supply
High precision, low drift, low power
INA129
10µV offset, ±0.1µV/°C drift, 134dB open-loop gain
120dB CMRR (G = 100), 100µV (max) offset, 0.4µV/°C
(max) drift
25μV (max) offset, 50nV/°C drift, 50μA (typ) Iq
20pA (max) bias current, 90dB (min) CMRR, 1MHz BW
1.8V min supply, 0.017mA/ch (max), 10μV offset (max),
0.05μV/°C drift (max)
2MHz, 5µV (max) offset, 0.05µV/°C (max) drift, 285μA
High CMRR, low cost, +2.7V to +5.5V
Best offset/noise combination, supply down to 1.8V,
low power
Precision, low input bias, low power
Zero drift, high precision, low power, EMI input
Provides very low offset voltage and near-zero drift
over time and temperature; SOT23
micoPower, SOT23 package
Lowest noise, power, price, precision zero-drift option
OPA2277 (dual)
OPA4277 (quad)
INA321, INA333
INA326, INA321
OPA131, OPA137
OPA335, OPA378,
OPA330
OPA735, OPA333,
OPA334
OPA379
OPA330, OPA333
Op Amp
Low Noise
Precision Op Amp
Precision Op Amp
125µV (max) offset, 1.5µV/°C drift, 20µA supply
0.1µV/°C Vos drift, 125µA, 900kHz, 0.4μVPP (0.1Hz to
10Hz) 0.4µ Vpp (0.1Hz to 10Hz), 0.9MHz
2.2V to 5.5V supply, 20µV voltage, 0.1µV/°C drift, 125µA
quiescent current
Low Power FDA
1.14mA quiescent current (typ), 4.6nV/√Hz voltage noise,
2.5V to 5.5V supply
ADS1258
Delta-Sigma ADC
16-channel, 24-bit, 125kSPS, 23.7kSPS/channel
ADS1271/74/78
*Page 19
ADS1298
*Page 16
ADS8317
Delta-Sigma ADC
24-bit, 128kSPS, 8-channel, 111dB SNR
ECG/EEG AFE
24-bit, 8 PGA, 8 ADC, plus RLD and RESP
SAR ADC
Low-Power ADC
SAR ADC
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max)
INL, differential input
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max) INL
16-bit, 500kSPS, 4/8 channels, with serial interface
Serial Output
ADC
High Volt. SAR ADC
Charge-Digitizing
ADC
16-bit, 4-/8-channel single-ended or 2-channel
differential input, 2.7V to 5V single supply ADC
16-bit, 250kSPS, 1.5LSB (max) INL, 92dB SNR
Dual current input, 20-bit ADC, ±0.005% INL reading
±0.5ppm FSR
REF02
REF102
Precision VREF
10V, Ultra
Precision
0.2% (max) initial accuracy, 10ppm/°C (max) drift, 1.4mA (max)
0.05% (max) initial accuracy, 2.5ppm/°C (max) drift,
1.4mA (max)
REF30xx
Low-Power,
Low-Drift Ref.
50µA, 0.2% initial accuracy, 50ppm/°C max drift, ±25mA
output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
REF32xx
Ultra-Low-Drift
Series Reference
100µA, 0.2% initial accuracy, 7ppm/°C max drift,
±10mA output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
Improves system accuracy
REF33xx
Very Low-Power
Series Reference
5µA, 0.15% initial accuracy, 30ppm/°C max drift,
±5mA output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V, 3.3V
Preserves battery life, fits into physically constrained
systems
REF30xx, REF31xx,
REF29xx
REF5010
10V, High-Precision, 0.05% initial accuracy, 3ppm/°C max drift, ±10mA
Very Low-Drift
output, 10V
Series Reference
Improves system accuracy
REF102
REF50xx
High-Precision,
Very Low-Drift
Series Reference
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 2.048V, 2.5V, 3.0V, 4.096V, 4.5V, 5.0V
Improves system accuracy
REF02
THS4521/22/24
*Page 19
Has excellent PSRR which makes it an ideal choice
for applications that run direct from batteries without
regulation
Low power, low noise enables high accuracy
Data Converters
ADS8326
ADS8331/32
*Page 18
ADS8341/2/3/4/5
*Page 18
ADS8519
DDC112
Fastest multi-channel, delta-sigma ADC, measures
all 16 inputs in <675µs
Simultaneous measurement, onboard decimation
filter
Complete front end, reduction in power and size,
increase reliability
Low power, small package, and wide supply range
ADS1256, ADS1255,
ADS8344
ADS1294, ADS1296,
ADS1198, ADS1258
ADS8326
Small package, wide supply range
Mux out feature can be used to reduce system part
count and overall cost
Easy to use
ADS8342
Single supply, high voltage inputs
High precision, true integrating function
ADS8515
DDC114, DDC118,
DDC232
Excellent line/load regulation, low noise
Excellent stability and line/load regulation
REF5050
REF5010
References
New products are listed in bold red.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
REF31xx, REF33xx,
REF29xx
21
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
MSP430F20xx
Ultra-Low-Power
16-bit MCU
1KB/2KB Flash, 128B RAM, SPI+I2C 16-bit MCU
8 ch. 12-bit ADC or 4 ch. 16-bit SD ADC, 4 x 4mm
package
MSP430F22x4
Ultra-Low-Power
16-bit MCU
8 to 32KB Flash, 512B/1KB RAM, SPI + I2C + UART/LIN
+ IrDA
12 ch. 10-bit ADC, 2 operational amplifiers
MSP430F23x0
Ultra-Low-Power
16-bit MCU
8 to 32KB Flash, 1KB/2KB RAM, SPI + I2C + UART/LIN
+ IrDA
Analog comparator, HW multiplier
MSP430F41x
Ultra-Low-Power
16-bit MCU
4 to 32KB Flash, 256B to 1KB RAM, SVS,
96 segment LCD
Analog comparator
MSP430F42x
Ultra-Low-Power
16-bit MCU
8 to 32KB Flash, 256B to 1KB RAM, SPI + UART, SVS,
128 segment LCD
3 x 16-bit SD ADC
MSP430F42x0
Ultra-Low-Power
16-bit MCU
16 to 32KB Flash, 256B RAM, 56 segment LCD
5 ch. 16-bit SD ADC, 12-bit DAC
MSP430F43x
Ultra-Low-Power
16-bit MCU
16 to 32KB Flash, 512B/1KB RAM, SPI + UART, SVS,
160 segment LCD
8 ch. 12-bit ADC, analog comparator
MSP430F44x
Ultra-Low-Power
16-bit MCU
32 to 60KB Flash, 1KB/2KB RAM, 2x SPI + UART, SVS,
160 segment LCD
8 ch. 12-bit ADC, HW multiplier
MSP430F47xx
Ultra-Low-Power
16-bit MCU
60KB Flash, 256B RAM, (4) USCI, 160 segment LCD
(4) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
MSP430F241x
Ultra-Low-Power
16-bit MCU
120KB Flash, 8KB RAM, (4) USCI, SVS, temp. sensor
8 ch. 12-bit ADC, analog comparator, HW multiplier
MSP430F261x
Ultra-Low-Power
16-bit MCU
120KB Flash, 8KB RAM, (4) USCI, SVS, DMA, temp.
sensor
Analog comparator, 2 ch. 12-bit DAC, 8 ch. 12-bit
ADC, HW multiplier
MSP430F471xx
Ultra-Low-Power
16-bit MCU
120KB Flash, 8KB RAM, (4) USCI, DMA 160 segment LCD
(7) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
MSP430F54xxA
Ultra-Low-Power
16-bit MCU
128 to 256KB Flash, 16KB RAM, (4) USCI, PMM, DMA,
temp. sensor
16 ch. 12-bit ADC, analog comparator, RTC, internal
voltage regulator for power optimization
MSP430FG42x0
Ultra-Low-Power
16-bit MCU
16 to 32KB Flash, 256B RAM, 56 segment LCD
5 ch. 16-bit SD ADC, 12-bit DAC, 2 integrated
op amps
MSP430FG43x
Ultra-Low-Power
16-bit MCU
32 to 60KB Flash, 1KB/2KB RAM, SPI + UART, SVS,
128 segment LCD
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, DMA, 3 op amps
MSP430FG461x
Ultra-Low-Power
16-bit MCU
92 to 120KB Flash, 4KB/8KB RAM, SPI + I2C + UART/LIN
+ IrDA, 160 LCD
12 ch. 12-bit ADC, 2 ch.12-bit DAC, A-comp, 3 op
amp, HW multiplier
MSP430FG47x
Ultra-Low-Power
16-bit MCU
32 to 60KB Flash, 2KB RAM, SPI + I2C + UART/LIN +
IrDA, 128 LCD controller
5 ch. 16-bit SD ADC, 2 ch. 12-bit DAC,
comparator_A, 2 op amps
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L137
*Page 15
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
OMAP-L138
TMS320C5000™
DSP
Power efficient, high performance
TMS320F28x™
32-Bit MCU
TMS320F2802x/3x
Piccolo™
32-Bit
Microcontroller
32-bit architecture, fixed- or floating-point code, up to
225MIPS operation
Up to 60MHz C28x™ core with optional control law
accelerator. Up to 128KB Flash, high resolution (150ps)
PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
TMS320F2823x,
TMS320F2833x
TMS320F283x
Delfino,
TMS320F280x
TMS320F283x
Delfino™
32-Bit
Floating-point
Microcontroller
Up to 300MHz C28x™ core. Up to 512KB Flash, high
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN, QEP,
external memory bus, DMA.
TMS320VC5506
DSP
200MHz, dual MAC, very low stand-by power of 0.12mW
Microcontroller integration, real-time control
performance
With dedicated, high precision peripherals, Piccolo
microcontrollers are the ultimate combination of
performance, integration, size, and low cost. Ideal for
precision sensing and control applications.
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point brings
increased performance and quicker development.
Ideal for precision sensing and control applications.
Supported by eXpressDSP™ and many other
software packages and tools
TMS320F2802x/3x
Piccolo,
TMS320F280x
TMS320VC5509A,
TMS320VC5502
Power Management
bq20z90-V110
bq24703
bq24721C
Battery Fuel
Gauge
Battery Charger
Battery Charge
Management
Instant accuracy better than 1% error over lifetime of the
battery
0V operation, ±0.4% charge voltage accuracy, integrated PWM
Multi-chemistry and multi-cell sync switch-mode charger
bq20z70, bq20z80
bq24702, bq24705
New products are listed in bold red.
additional product information see designated page number.
*For
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
Automatically adjusts for battery aging, battery self
discharge and temperature inefficiencies
Dynamic power management, multichemistry
High efficiency, pack and system protection functions
22
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Electrocardiogram (ECG)/Portable ECG and Electroencephalogram (EEG)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
bq29330
Battery Safety
Battery pack full-protection analog front end
DCH010505D
1W, 3kV isolation, minimal external components
TPS65130
TPS717xx
TPS718xx-yy
TPS780xx
Galvanic Isolated,
DC/DC Conv.
Load Switch with
Controller Turn-On
Current Limited
Load Switch
Voltage Supervisor
DC/DC Converter
Boost Converter
with Bypass
Switch
Step-Down
Converter
Step-Down Conv.
Dual Output
Step-Down Conv.
Buck-Boost
Converter
Boost Converter
Single-Channel LDO
Dual-Channel LDO
LDO with DVS
TPS79901
Single Channel LDO
Very high rejection of power-source noise
CC1101
Sub-1GHz RF
Transceiver
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Wake-on-radio functionality; integrated packet handling
with 64B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2 to 500kbps; extremely fast PLL turn-on/hop time
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temperature
range; AES-128 security module
Ideal for low-power systems; any low-end MCU
can be used; backwards compatible with existing
systems; suitable for fast frequency-hopping systems
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal for
industrial applications; no external processor needed
for secure communication
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
MCU, Flash and RAM in one package; four flexible power
modes for reduced power consumption; includes CC1101
transceiver frequency synthesizer; built-in AES-128
encryption coprocessor
Excellent RX sensitivity, low power, easy to use
development tools
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication
RF design System-on-Chip for quick time to market.
Provides a robust and complete ZigBee USB dongle
or firmware-upgradable network node
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity, selectivity
and blocking performance
Fast-to-market Bluetooth® low energy compliant
solution
Single-chip 802.11b/g/n WLAN and Bluetooth® solution
using TI’s digital radio processor technology using a
single antenna.
Single-chip 802.11a/b/g/n WLAN and Bluetooth® solution
using TI's digital radio processor technology using a
single antenna.
Sophisticated low-power technology ideal for battery operated
solutions; coexistence features enable simultaneous WLAN and
Bluetooth® operations; supports ANT+ standard.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
Second
Generation
Z-Stack™
Network Processor
ZigBee stack and radio in one chip; implements ZigBee
certified stack; configurable device type and network
settings; excellent selectivity and blocking performance
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery operated systems; excellent
coexistence with Bluetooth® technology and Wi-Fi.
ECG Analog Front
End Module for
the C5515 ECG
Medical Dev. Kit
12-lead ECG output using 10 electrode input; 0.05Hz to
150Hz bandwidth; leads off detection; heart beat rate
display
Based on industry’s lowest power DSP processor –
TMS320C5515
TPS22902
TPS22946
TPS3808Gxx
TPS54350
TPS61097-33
TPS62110
TPS62230
TPS62400
TPS63030
Low on resistance, controlled turn-on, ultra small 0.64mm2
package, quick output discharge
Configurable current limit, ultra-small package, 1µA
quiescent current at 1.8V
Low quiescent current, programmable-delay
4.5 to 20VIN 3A DC/DC w/integrated switch FET, sync pin, enable
Highly efficient, operates down to 0.3V; bypass switch; 5nA
shutdown current; SOT-23
3.1V to 17V VIN, 1.5A conversion, synchronization pin, low
battery indicator, power save mode
Up to 90dB PSRR, excellent AC and transient load regulation
180° out of phase operation, serial interface
1A switch, automatic transition between step down and
boost mode
800mA switch, adjustable, dual output, positive/negative boost
Very high rejection of power-source noise
Very high rejection of power-source noise
Dynamic voltage scaling (DVS) with low IQ 500nA
Provides individual cell voltages and battery voltage
to battery management host
Safety isolation, removal of ground loops
Ultra-small, fully integrated solution
Ultra-small, low quiescent current current limited switch
DCH010512/15
DCR021205
TPS22901, TPS22922,
TPS22924C, TPS22960
TPS22949, TPS22945
Circuit initialization and timing supervision
Eliminate beat noise/ceramic caps/FPGA/integration
Supper efficient boost, works over entire battery range,
low quiescent current, integrate the bypass switch,
small package
Very low noise/high efficiency
TPS310x
TPS54550
Low noise regulation, 12mm2 solution size
Flexible voltage adjustment for processors and MCUs
TPS62260
TPS62410
Extending application run time, small solution
TPS61020
Two supplies from one switcher
Low-noise power rails for sensitive analog components
Low-noise power rails for sensitive analog components
DVS voltage designed to operate with MSP430 to
increase power savings
Low-noise power rails for sensitive analog components
TPS795xx, TPS799xx
TPS719xx-yy
TPS78101
TPS62050
TPS79501, TPS74301
RF ICs
RF Transceivers
RF Systems-on-Chip
CC2560
CC1110/11
CC2530/CC2531
CC2540
WL1271
WL1273
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Second Gen.
System-on-Chip
2.4GHz IEEE
802.15.4/RF4CE/
ZigBee
2.4GHz Bluetooth®
Low Energy
Compliant RF
System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
CC2500
CC2530
CC2510, CC2511
CC2590/91,
CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Toolkits
TMDXMDKEK1258
*Page 20
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
New products are listed in bold red. Preview products are listed in bold blue.
23
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Overview
Oxi Lvi
MSP430/DSP
Pulse
Rate
LoBatt
DeMUX
The oximeter senses and calculates
the amount of light at those wavelengths proportional to the oxygen
saturation (or desaturation) of the
hemoglobin. The use of light in the
absorbency measurement requires
the designer to have a true “light-tovoltage” conversion using current as
the input signal.
Amplifiers and Processors
The classic resistor-feedback trans­
impedance amplifier and capacitorfeedback switched integrator are suitable for pulse oximetry applications.
In either amplifier configuration, the
resulting output voltage is read by an
analog-to-digital converter and serialized for the MSP430™ microcontroller
or TMS320™ DSP for processing.
Processor selection should be based
on signal-processing needs. TI has a
wide variety of MSP430 products offering up to 25MIPS performance and
extensive mixed-signal integration.
For mid-range to high-end systems
requiring much higher digital signal
performance for enhanced signal conditioning and processing, low-power
DSP processors such as C55x™ can
be used. These processors offer higher
than 100MIPS at very low power.
ADC12
LED
Select
Probe Connector
Red LED Gain
Psuedo
Analog Ground
Infrared LED Gain
Cable
Pin Diode
Red LED ON/OFF
Infrared LED ON/OFF
Light sources, typically light-emitting
diodes (LEDs), shine visible red and
infrared light. Deoxygenated hemo­
globin allows more infrared light to
pass through and absorbs more red
light. Highly oxygenated hemoglobin
allows more red light to pass through
and absorbs more infrared light.
DAC12_1
DAC12_0
The pulse oximeter measures blood
oxy­genation by sensing the infrared
and red-light absorption properties of
deoxy­genated and oxygenated hemoglobin. The oximeter is comprised of a
sensing probe that attaches to a patient’s
ear lobe, toe or finger and is connected
to a data acquisition system for the
calculation and display of oxygen saturation level, heart rate and blood flow.
G1
TransImpedance
Amplifier
Pin Diode
Infrared LED
OA0
Red LED
I
R
R
2nd
Stage
G2
MUX
OA1
I
R
Apart from the MCU and four transistors, only passive components are needed for
this design.
Low-End Portable Pulse Oximeter
For low-end designs, TI’s highly integrated MSP430FG437 reduces the
number of external components. The
design of a non-invasive optical pulse
oximeter using the MSP430FG437
microcontroller (MCU) consists of a
peripheral probe combined with the
MCU displaying the oxygen saturation
and pulse rate on an LCD glass. In this
application, the same sensor is used for
heart-rate detection and pulse oximetry.
The probe is placed on a peripheral
point of the body, such as a fingertip,
an ear lobe or the nose. The probe
includes two LEDs — one in the visible
red spectrum (660nm) and the other
in the infrared spectrum (940nm). The
percentage of oxygen in the body is
determined by measuring the intensity
from each frequency of light after it is
transmitted through the body. Then,
the ratio between these two intensities
is calculated.
The diagram below demonstrates the
implementation of a single-chip, portable pulse oximeter using the ultra-lowpower capability of the MSP430 MCU.
20Ω
P2.2
5kΩ
5
1kΩ
MS430FG437
DAC0
Probe
Integrated
LEDs
Infrared
Visible Red
10
P2.2
1kΩ
5kΩ
20Ω
LED drive circuit.
Diagnostic, Patient Monitoring and Therapy Applications Guide
24
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
necessary, there is a need for higherperformance processors and highprecision analog components that
provide lower system power.
Because of the high level of analog
integration, the number of external
components is kept to a minimum.
Keeping ON time to a minimum and
power cycling the two light sources
also reduces power consumption.
For example, several sources of interference such as neon lamps, UV lamps
and other light emitters may influence
the optical path between LEDs and the
photoreceiver, affecting measurement
accuracy. There could also be signal
distortion caused by motion that
Mid-Range and High-End
Applications
For mid-range and high-end applications where higher performance and
higher measurement accuracy are
occurs while the reading is taken.
Sophisticated DSP technology can be
applied to eliminate or reduce these
effects and extract the vital signal of
interest. Often, these DSP technologies require high-sample-rate signalprocessing operations such as demodulation, digital filtering, decimation, and
frequency-domain analysis, which can
be efficiently mapped to a C55x™
low-power digital signal processor.
Operator/Patient Feedback and Monitors
Analog Front End
Photodetector
ADC
Backlight
Filter
REF
Processor
Clock
Keypad
Touch Screen
Control
Audio
Alerts
DAC
LED
Drivers
DAC
Core and
I/O Power
Level Shift
SDRAM
Power Options
Battery
Management
ESD
System
Power
SDRAM
AC/DC
Adaptor
Interface
Battery
Memory
Power
Memory
LEGEND
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Pulse oximeter system block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
25
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Signal Acquisition Challenges
The resistor-feedback amplifier circuit
is the most common bioelectric trans­
impedance circuit. With the amplifier
used in the inverting configuration,
the light shining on a photodiode produces a small current that flows to the
amplifier sum10MΩ
ming junctions
and through
the feedback
OPA353
VO
resistor. Given Photodiode
the very large
feedback
resistor value, this circuit is extremely
sensitive to changes in light intensity.
For example, an input light signal of
just 0.001µW can produce a full-swing
output.
Depending on design requirements, it
can be very useful to achieve output
swing down to or below ground. The
auto-zero transimpedance amplifier
configuration shown in Figure A at right
allows swing to ground, while the one
in Figure B allows swing very close to
ground. A pull-down resistor tied to
–5V allows swing slightly below ground
to minimize errors as the output gets
very close to 0V.
TI’s OPA380 is a monolithic combination of the high-speed OPA355 and
auto-zero OPA335 amplifiers. It offers
a 90MHz gain-bandwidth product and
performs well as a 1MHz transimpedance amplifier with extremely high
precision (25µV maximum offset and
0.1µV/°C maximum drift).
Depending on design requirements,
the switch integrator can be a very
effective solution. TI’s IVC102 does
not have the thermal noise of a feedback resistor and does not suffer from
stability problems commonly found
in transimpedance amps with a large
feedback resistor.
Additionally, IVC203 allows for
synchronized sampling at
an integer multiple of the
AC line frequency, giving
extremely high noise rejection.
Transimpedance gain can be
easily changed by extending or
shortening integration time with
switch S2.
A. Dual Supply
IIN
R1
REF3140
+2.5V
Photodiode
–2.5V
ADS8320
OPA340
or OPA350
C1
1MΩ
+2.5V
R2
Transimpedance Amplifier
OPA335
Requirements
• Low input bias current over
–2.5V
temperature range of interest
• Low input capacitance relative to photodiode capacitance
• High gain-bandwidth product
B. Single Supply
• Low voltage noise
IIN
R1
• For maximum precision, low
+5V
offset drift over temperature
• For single-supply systems:
Photodiode
OPA340
• Rail-to-rail input (including
or OPA350
OV) and output if operating
the photodiode in photoC1
1MΩ
voltaic (zero-bias) mode
+5V
• Rail-to-rail output only if
R2
operating the photodiode
OPA335
in photoconductive mode
(biased)
40kΩ*
• Shutdown and/or low
*Optional pull-down resistor to
allow below ground output swing. –5V
supply current if batterypowered system
C2
REF3140
ADS8320
C2
RF
+5V
OPA380
VO
0V to 4.9V
Photodiode
CDIODE
–
20mV
RP
+
1MΩ
(Optional
Pulldown
Resistor)
67pF
–5V
100
kΩ
75pF
Using one photodiode with two
IVC102s eliminates dark current and
ambient light errors, since errors
common to both can be subtracted.
Diagnostic, Patient Monitoring and Therapy Applications Guide
26
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Design Hints
A small (<1pF) capacitor in the feedback loop (CF) controls gain-peaking
caused by diode capacitance. Noise
(voltage-output fluctuation) is caused
by resistor noise, amplifier and current
noise, and environmental noise pickup
(e.g., 50Hz or 60Hz line noise). To minimize noise in the circuit, the designer
should choose a low-noise amplifier,
select the largest practical feedback
resistor, RF shield the amplifier inputs,
include low-pass filtering and use good
PCB layout techniques.
VB
Mid-Range Solution Advantages
• Single-chip solution
• High resolution
• Low noise
• Wide input range by adjustable
integration time
• No need for DC corrections of the
diode current
Note: “Pulse Oximeter Design using
MSP430FG43x” (slaa274)
www-s.ti.com/sc/techlit/slaa274
C1
60pF
C3
C2
5
4
14
30pF
10pF
S2
3
IIN
10
2
VO
S1
1
9
Photodiode
11
Analog
Ground
If the photodiode shunt resistance is
much larger than that of the feedback
resistor, offset voltage is not significant.
If offset voltage stability is paramount,
an auto-zero solution including the
OPA335 is best.
To achieve the highest precision levels,
system designers should choose the
OPA380. Designed to meet exacting
transimpedance application requirements, the OPA380 provides an
unbeatable combination of speed
(85MHz GBW over 1MHz transimpedance bandwidth) and precision (25µV
maximum offset, 0.1µV/°C drift and low
1/f noise). A discrete alternative is to use
the OPA365, OPA350, or OPA355,
adding the OPA335 in the integratorsstabilized transimped­ance configuration
for circuits requiring low offset and drift.
Adding the OPA335 integrator to a
basic transimpedance amplifier will also
reduce its very low frequency noise.
V+
IVC102
6
12
13
S1
Logic Low S2
Closes Switches
Positive or Negative
Signal Integration
V–
Digital
Ground
VO =
–1
C INT
∫I
IN (t) dt
0V
Hold
Integrate
Hold
Reset
S1
S2
High-End Solution Advantages
• Very high resolution
• High noise immunity due to
differential input
• High noise immunity due to synchronization on AC supply possible
• High noise immunity due to free
access on integration and reset
switches by software
• No need for DC correction of the
diode currents
• Huge input range can be covered
(>24-bit) due to free programmable
integration times
IVC102a
S2a
S1a
ADC
VREF
S2b
Red and IR
S1b
VREF
MSP430
or
DSP
ADS1255
IVC102b
High-end solution block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
27
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Dual, Current-Input, 20-Bit Charge Digitizing ADC
DDC112
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/DDC112
Key Features
• Single-chip solution for measuring
photodiodes
• High precision, true integrating
function
• Low noise: 3.2ppm, rms
• Outstanding linearity: ±0.005% INL
reading ±0.5ppm FSR
• Programmable full-scale: 50 to
1000pC
• Single supply: +5V supply
• Packaging: SO-28, TQFP-32
The DDC112 is a dual input, wide dynamic range, charge-digitizing ADC which
allows low-level current output ICs to be connected directly to its inputs. Charge
integration is continuous as each input uses two integrators; while one is being
digitized, the other is integrating. In addition to the internal programmable fullscale ranges, external integrating capacitors allow an additional user-settable,
full-scale range of up to 1000pC. A high-speed serial shift register, which holds
the result of the last conversion, can be configured to allow multiple, cascaded
DDC112s, minimizing interconnections.
AVDD
CAP1A
CAP1A
AGND
VREF
DVDD
CHANNEL 1
DGND
DDC112
DCLK
IN1
CAP1B
CAP1B
Applications
CAP2A
CAP2A
• Blood analysis
• Liquid/gas chromatography
• Direct photosensor digitization
• Infrared pyrometry
Dual
Switched
Integrator
∆Σ
Modulator
CHANNEL 2
IN2
CAP2B
CAP2B
DVALID
DXMIT
DOUT
DIN
Digital
Input/
Output
Digital
Filter
RANGE2
RANGE1
RANGE0
Control
Dual
Switched
Integrator
TEST
CONV
CLK
DDC112 functional block diagram.
—–
1.1nV/√Hz Noise, Low-Power, Precision Op Amp
OPA211, OPA2211
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/OPA211
Key Features
• Input voltage noise: 80nVPP,
0.1Hz to 10Hz
• Low offset voltage: 50µV (max)
• Low offset voltage drift: 0.15µV/°C (typ)
• Supply current: 3.6mA/ch
• Gain bandwidth product: 80MHz
(G = 100)
• Slew rate: 27V/µs
• Supply range: ±2.25V to ±18V, +4.5V
to +36V
• Output current: 30mA
• Unity gain stable
• Packaging: Tiny DFN-8, MSOP/SO-8
—–
The OPA211 series achieves very low 1.1nV/√Hz noise density with a supply current of only 3.6mA. It offers rail-to-rail output swing to maximize dynamic range.
In precision data acquisition systems, the OPA211 provides <1µs settling time to
16-bit accuracy even for 10V output swings. By combining AC performance with
only 50µV of offset and low drift over temperature, the OPA211 is able to drive fast,
high-precision ADCs or buffer the outputs of high-resolution DACs.
OPA2211
OPA211
NC
1
8
Enable
OUT A
1
–IN
2
7
V+
–IN A
2
+IN
3
6
OUT
+IN A
3
V–
4
5
NC
V–
4
A
B
8
V+
7
OUT B
6
−IN B
5
+IN B
Applications
• Medical instruments
• Portable medical devices
• Ultrasound amplifiers
• Low-noise, low-power signal
processing
MSOP−8
MSOP−8
Pin configurations.
Diagnostic, Patient Monitoring and Therapy Applications Guide
28
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Pulse Oximeter (PO or SpO2) Analog Front End Module for the C5515 PO or SpO2 Medical
Development Kit
TMDXMDKPO8328
Get samples, datasheets and evaluation modules at: www.ti.com/tmdxmdkpo8328
Key Features
• PO AFE module key components
•ADS8328: low power, 16-bit, 500ksps,
analog-to-digital converter (ADC)
•DAC7573: quad, 12-bit, low power,
voltage output digital-to-analog
converter DAC
•OPA381: precision, low power,
transimpedance amplifier
(current to voltage converter)
•REF5025: low noise, very low drift,
precision voltage reference
• DS MDK system features
•Based on industry’s lowest power
DSP processor – TMS320C5515
•Display of oxygen level percentage
ranging from zero to 100 percent
•Display of pulse rate, ranging from
20 to 300
•Real-time display of plethysmogram on PC
•Sensor off detection
•Common signal conditioning path
for red and infrared signal
To reduce the time to market for medical device companies, TI has launched a set
of medical application development tools with complete signal chain designs and
software for electrocardiograms, digital stethoscopes, and pulse oximeter products. Each of the three medical development kits (MDKs) is comprised by purchasing an analog front-end (AFE) module with specific circuitry design optimized for
each end product plus a TMS320C5515 DSP Evaluation Module (EVM) based on
the industry’s lowest power DSP – TMS320C5515. MDKs provide a great evaluation platform to help medical device manufacturers focus on product differentiation, like algorithm development and feature enhancement.
The TMDXMDKPO8328 Pulse Oximeter (PO or SpO2) Analog Front End (AFE)
module consists of the PO AFE module, a processor board (C5505 DSP evaluation
module), a set of collateral and C5505 based application sample code to implement the PO application. The PO MDK delivers a complete signal chain solution to
enable PO developers to build a complete PO system quickly for evaluation and
get to production faster.
Applications
• Pulse oximeters
• Patient monitoring
Component Recommendations
Component
Description
Key Features
Other TI
Solutions
Benefits
Amplifiers
IVC102
OPA141
Transimpedance
Amp
Precision Op Amp
Precision switched integrator
OPA211/2211
*Page 28
OPA334/5
Precision Op Amp
10MHz, 6.5nV/√Hz, ±4.5V to ±18V, 1.8mA typical, FET
input: IB = 20pA max
—
1.1nV/√Hz noise at 1kHz, ±2.25V to ±18V supply, 80MHz BW
Op Amp
2MHz, 5µV (max) offset, 0.05µV/°C (max) drift, 285μA
OPA336
OPA350
OPA353
Op Amp
Op Amp
MicroAmplifier™
Series
Op Amp
Transimpedance
Amp
12V Op Amp
CMOS Op Amp
125µV (max) offset, 1.5µV/°C drift, 20µA supply
OPA363
OPA380
OPA725
OPA726
OPA735
OPA365
Zero-Crossover
Op Amp
Zero-Crossover
Op Amp
Reduces noise by averaging the input noise of the
sensor, amplifier, and external sources
Common mode voltage range includes GND
OPA827
Unity gain stable, RRO, wide supply range
OPA227, OPA827
Provides very low offset voltage and near-zero drift
over time and temperature; SOT23
micoPower, SOT23 package
OPA735, OPA333,
OPA334
OPA379
500µV VOS, 38MHz, 2.5V to 5V supply
High speed, single supply, rail-to-rail
1.8V, high CMR, RRIO, shutdown
90MHz GBW, over 1MHz transimpedance BW, 25µV offset
(max), 0.1µV/°C drift (max)
Very low noise, high speed, 12V CMOS
4V to 12V, 20MHz GBW, 30V/µs slew rate,
0.0003% (typ) at 1kHz THD+N
2.7V to 12V, 0.75µA (max) IQ/ch, 1.6MHz GBW,
115dB (min) CMRR, RRO
1.8V to 5.5V, 50MHz BW, 25V/µs slew rate, 0.0004% (typ)
THD+N, 4.5nV/√Hz at 100kHz, RRIO
OPA364
OPA350, OPA335
OPA727
Outstanding ac performance, excellent CMRR, PSRR
Zero-crossover input offers excellent CMRR over
entire input range
Zero-crossover, high speed, low input bias, low noise,
RRIO
New products are listed in bold red.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
Precision, dynamic range 4 to 5 decades, excellent
long term stability
29
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Component Recommendations (Continued)
Component
Description
Key Features
Other TI
Solutions
Benefits
Data Converters
ADS8318
High-Speed SAR
16-bit, 500kSPS, 18mW at 500kSPS power, ±1 LSB INL
Precision, excellent AC/DC performance
ADS8319
ADS8317
SAR ADC
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max)
INL, differential input
Low power, small package, and wide supply range
ADS8326
ADS8326
Low-Power ADC
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max) INL
Small package, wide supply range
DDC112
*Page 28
Dual Current
Input ADC
Wide dynamic range, charge digitizing, 20-bit ADC
Single-chip solution
REF31xx
Low-Drift Series
Reference
0.2% initial accuracy, 15ppm/°C max drift, ±10mA
output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
REF32xx
Ultra-Low-Drift
Series Reference
100µA, 0.2% initial accuracy, 7ppm/°C max drift, ±10mA
output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
Improves system accuracy
REF33xx
Very-Low-Power
Series Reference
5µA, 0.15% initial accuracy, 30ppm/°C max drift, ±5mA
output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V, 3.3V
Preserves battery life, fits into physically constrained
systems
REF30xx,
REF31xx, REF29xx
REF50xx
High-Precision,
Very-Low-Drift
Series Reference
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 2.048V, 2.5V, 3.0V, 4.096V, 4.5V, 5.0V, 10V
Improves system accuracy
REF02
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Ultra-Low-Power
16-Bit MCU
Applications
Processor
1KB/2KB Flash, 128B RAM, SPI+I2C
8 ch. 12-bit ADC or 4 ch. 16-bit SD ADC, 4 x 4mm
package
12 ch. 10-bit ADC, 2 op amps
References
REF30xx,
REF33xx, REF29xx
Processors
MSP430F20xx
MSP430F22x4
MSP430F23x0
MSP430F41x
MSP430F42x
MSP430F42x0
MSP430F43x
MSP430F44x
MSP430F47xx
MSP430F241x
MSP430F261x
MSP430F471xx
MSP430F54xxA
MSP430FG42x0
MSP430FG43x
MSP430FG461x
MSP430FG47x
OMAP3530
OMAP-L137
Low-Power
Applications
Processor
8 to 32KB Flash, 512B/1KB RAM, SPI + I2C + UART/LIN
+ IrDA
8 to 32KB Flash, 1KB/2KB RAM, SPI + I2C + UART/LIN
+ IrDA
4 to 32KB Flash, 256B to 1KB RAM, SVS,
96 segment LCD
8 to 32KB Flash, 256B to 1KB RAM, SPI + UART, SVS,
128 segment LCD
16 to 32KB Flash, 256B RAM, 56 segment LCD
16 to 32KB Flash, 512B/1KB RAM, SPI + UART, SVS,
160 segment LCD
32 to 60KB Flash, 1KB/2KB RAM, 2x SPI + UART, SVS,
160 segment LCD
60KB Flash, 256B RAM, (4) USCI, 160 segment LCD
120KB Flash, 8KB RAM, (4) USCI, SVS, temp. sensor
120KB Flash, 8KB RAM, (4) USCI, SVS, DMA, temp. sensor
120KB Flash, 8KB RAM, (4) USCI, DMA, 160 segment LCD
128 to 256KB Flash, 16KB RAM, (4) USCI, PMM, DMA,
temp. sensor
16 to 32KB Flash, 256B RAM, 56 segment LCD
Analog comparator, HW multiplier
Analog comparator
3 x 16-bit SD ADC
5 ch. 16-bit SD ADC, 12-bit DAC
8 ch. 12-bit ADC, analog comparator
8 ch. 12-bit ADC, HW multiplier
(4) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
8 ch. 12-bit ADC, analog comparator, HW multiplier
Analog comparator, 2 ch. 12-bit DAC, 8 ch. 12-bit ADC,
HW multiplier
(7) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
16 ch. 12-bit ADC, analog comparator, RTC, internal
voltage regulator for power optimization
5 ch. 16-bit SD ADC, 12-bit DAC, 2 integrated op amps
32 to 60KB Flash, 1KB/2KB RAM, SPI + UART, SVS,
128 segment LCD
92 to 120KB Flash, 4KB/8KB RAM, SPI + I2C + UART/LIN
+ IrDA, 160 LCD
32 to 60KB Flash, 2KB RAM, SPI + I2C + UART/LIN +
IrDA, 128 LCD controller
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, DMA, 3 op amps
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, A-comp, 3 op
amp, HW multiplier
5 ch. 16-bit SD ADC, 2 ch. 12-bit DAC, comparator_A,
2 op amps
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L138
New products are listed in bold red.
30
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Component Recommendations (Continued)
Component
Description
Key Features
Other TI
Solutions
Benefits
Processors (Continued)
TMS320C5000™
DSP
Power efficient, high performance
Fixed-point DSP with industry’s best combination of
standby and dynamic power consumption
TMS320C5505
Low-Power DSP
16-/8-bit EMIF, 320K bytes on-chip RAM, USB 2.0
full- and high-speed device
High-performance, low-power
TMS320F28x™
32-Bit MCU
TMS320F2802x/3x
Piccolo™
32-Bit
Microcontroller
32-bit architecture, fixed- or floating-point code, up to
225MIPS operation
Up to 60MHz C28x™ core with optional control law
accelerator. Up to 128KB Flash, high resolution (150ps)
PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
TMS320F2823x,
TMS320F2833x
TMS320F283x
Delfino,
TMS320F280x
TMS320F283x
Delfino™
32-Bit
Floating-point
Microcontroller
Up to 300MHz C28x™ core. Up to 512KB Flash, high
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN, QEP,
external memory bus, DMA.
TMS320VC5506
DSP
200MHz, dual MAC, very low stand-by power of 0.12mW
Microcontroller integration, real-time control
performance
With dedicated, high precision peripherals, Piccolo
microcontrollers are the ultimate combination of
performance, integration, size, and low cost. Ideal for
precision sensing and control applications.
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point brings
increased performance and quicker development.
Ideal for precision sensing and control applications.
Supported by eXpressDSP™ and many other software
packages and tools
TMS320VC5509A
Low-Power DSP
Up to 200MHz, dual MAC, 256KB RAM/64KB ROM,
USB 2.0 full speed, MMC/SD, 10-bit ADC
Power efficient, large on-chip memory, rich peripheral
set allows for various portable connectivity; C55x code
compatibility
C550x DSP
bq2410x
TMS320F2802x/3x
Piccolo,
TMS320F280x
TMS320VC5509A,
TMS320VC5502
Power Management
bq2406x
Battery Charger
Linear 1-cell Li-Ion charger with thermal regulation, 6.5V
OVP, temp sense
Good for space-limited designs with need for battery
safety
bq27500
Fuel Gauge
System side Impedance Track™
Accurately know remaining battery capacity, state-ofcharge, run-time to empty
TPS61081
LED Boost
Converter
Input to output isolation
Protection from short between any pins and between
any pin to ground
TPS61042
TPS61093
OLED Boost
Converter
Wide VIN range, input-output disconnect
Flexible, fail safe solution
TPS61080
TPS62230
Step-Down
Converter
Up to 90dB PSRR, excellent AC and transient load
regulation
Low noise regulation, 12mm2 solution size
TPS62260
TPS62400
Dual Output StepDown Converter
180° out of phase operation, serial interface
Flexible voltage adjustment for processors and MCUs
TPS62410
TPS63030
Buck-Boost
Converter
1A switch, automatic transition between step down and
boost mode
Extending application run time, small solution
TPS61020
TPS717xx
Single-Channel
LDO
Very high rejection of power-source noise
Low-noise power rails for sensitive analog
components
TPS795xx,
TPS799xx
TPS71710
Low-Noise SingleChannel LDO
High bandwidth, very high rejection of power source
noise
Low-noise power rails for sensitive analog
components
TPS759xx,
TPS739xx
TPS718xx-yy
Dual-Channel
LDO
Very high rejection of power-source noise
Low-noise power rails for sensitive analog
components
TPS719xx-yy
TPS780xx
LDO with DVS
Dynamic voltage scaling (DVS) with low IQ 500nA
DVS voltage designed to operate with MSP430™ to
increase power savings
TPS78101
TPS78001
Single-Channel
LDO
Dual-level, fixed output voltages, ultra-low IQ
Adjustable VOUT for optimal performance, longer
battery life
TPS78101
CC1101
Sub-1GHz RF
Transceiver
Wake-on-radio functionality; integrated packet handling
with 64B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2 to 500kbps; extremely fast PLL turn-on/hop time
Ideal for low-power systems; any low-end MCU can
be used; backwards compatible with existing systems;
suitable for fast frequency-hopping systems
CC2500
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temperature
range; AES-128 security module
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal for
industrial applications; no external processor needed
for secure communication
CC2530
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
MCU, USB 2.0, Flash and RAM in one package; four
flexible power modes for reduced power consumption;
includes CC1101 transceiver frequency synthesizer;
built-in AES-128 encryption coprocessor
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
RF ICs
RF Transceivers
RF Systems-on-Chip
CC2560
CC1110/11
2.4GHz Bluetooth®
2.1 Chipset
Sub-1GHz
System-on-Chip
CC2510, CC2511
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
31
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Pulse Oximeter
Component
Description
Key Features
Other TI
Solutions
Benefits
RF ICs (Continued)
RF Systems-on-Chip (Continued)
CC2530/31
Second
Generation
System-on-Chip
Solution for
2.4GHz IEEE
802.15.4/RF4CE/
ZigBee
Excellent RX sensitivity, low power, easy-to-use
development tools
RF design SOC for quick time to market; provides a
robust and complte ZigBee USB dongle or firmwareupgradable network node.
CC2530ZNP
Second
Generation
Zstack Network
Processor
ZigBee stack and radio in one chip; implements ZigBee
certified stack; configurable device type and network
settings
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery-operated, excellent selectivity and
blocking performance systems; excellent coexistence
with Bluetooth ® technology and Wi-Fi.
CC2540
2.4GHz
Bluetooth® Low
Energy compliant
RF System-on-Chip
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity, selectivity
and blocking performance
A fast-to-market Bluetooth® low energy compliant
solution
WL1271
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
Single-chip 802.11b/g/n WLAN and Bluetooth® solution
using TI’s digital radio processor technology using a
single antenna.
Single-chip 802.11a/b/g/n WLAN and Bluetooth® solution
using TI's digital radio processor technology using a
single antenna.
Sophisticated low-power technology ideal for battery operated
solutions; coexistence features enable simultaneous WLAN
and Bluetooth® operations; supports ANT+ standard.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
Second
Generation
Z-Stack™
Network Processor
ZigBee stack and radio in one chip; implements ZigBee
certified stack; configurable device type and network
settings; excellent selectivity and blocking performance
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery operated systems; excellent
coexistence with Bluetooth® technology and Wi-Fi.
Pulse Oximeter
(PO or SpO2)
Analog Front
End Module for
the C5515 PO or
SpO2 Medical
Development Kit
Display of oxygen level percentage ranging from zero to
100 percent; display of pulse rate, ranging from 20 to
300; real-time display of plethysmogram on PC; sensor
off detection; common signal conditioning path for red
and infrared signal
Based on industry’s lowest power DSP processor –
TMS320C5515
WL1273
CC2590/91,
CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Toolkits
TMDXMDKPO8328
*Page 29
New products are listed in bold red. Preview products are listed in bold blue.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
32
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Portable Respiration Device
Other TI Components to
Consider
TMS320C2000™ 32-bit controllers are
used in portable respiration applications
like portable oxygen concentrators
because the real-time control capability
allows for very precise control of the
BLDC motor, even at high speeds. This
optimizes system power consumption
and enhances the durability and relia­
bility necessary in portable respiratory
equipment.
A portable respiration device supports
a patient with the correct dose of
oxygen. One pressure sensor in front
of the valve measures the breathe-in
air and another one after the valve
measures the breathe-out pressure.
A microprocessor uses the data from
the two pressure sensors and single
flow sensor to calculate the output of
the valve that is regulating the airflow.
The medical staff can set the right air
flow by a touch screen or key pad. A
portable device, used in an ambulance
for example, has sophisticated power
management circuitry to support mains
and battery operation.
• F2802x/F2803x Piccolo™ series
32-bit MCUs
• DRV103 as valve driver
• Power amplifier family OPA54x,
OPA56x as valve driver
• bq power management ICs for
battery charging and fuel gauge
• LED drivers
• Low-power wireless for future
designs
• RS-485 (SN65HVD3082), CAN
(SN65HVD251) or other interface ICs
for the communication between the
sensor and controller board
• Stellaris® Cortex M3 microcontrollers
Further Information
Pressure sensors play an important role for respiration equipment.
See page 34 for a short tutorial on
pressure sensing techniques and
considerations.
Oxygen
Valve
Pinch
Valve
Flow
Sensors
O2
Air
Valve
Heater and
Temp Control
Mixer
Mixer
Valve
Valve
Breath
Entry
Pump
Sensor
Exhalation
Valve
Humidifier
Pump
Compressor
Air
Airway
Pressure
Sensor
Sensor
Pump
Pump
Sensor
Water Level Sensor
DAC
DAC
Valve Drive
Amplifiers
DAC
DAC
Air Flow and
Pressure
Controller
1 2
6 7
1 323445 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
1 2
6 7
1 3234 45 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
1 2
6 7
1 3234 45 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
1 2
6 7
1 323445 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
Backlight
Touch Screen
Control
Low Noise Power
ADC
Sensor
Amplifiers
System Control
Audio
ADC
AC Line
Isolated AC/DC
Supply
(Green Mode)
Clock
REF
Level Shift
Memory
Power
Back-Up
Battery
System
Power
FLASH/
EPROM
Plug
Logic
DAC
Audio Amp
SDRAM
Temp Sense
Fan Control
LCD
DAC
ADC
DAC
DAC
Operator/Patient
Feedback
and Monitors
Core and
I/O Power
PC
Interfaces
Medical
System
Interfaces
LEGEND
Power and Battery Management
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Portable respiratory device system block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
33
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Pressure sensors convert a physical
value (weight, level, force, and flow)
into a differential signal in the mV/V
range and are referred to as metal
thick-film, ceramic or piezo-resistive.
The majority of designers use the
cost-effective piezo-sensors (25mbar
to 25bar). However, these are very
non­linear, temperature dependent and
have large offset and offset drift. Plus,
they require attention to electronic
calibration and compensation.
2.7
Uncorrected
Bridge Output
2.4
Nonlinaerity (%FSR)
2.1
1.8
1.5
1.2
0.9
0.6
0.3
Corrected
Bridge Output
0
–0.3
The block diagram (below) shows the
functional block diagram of a pressure
signal conditioning system.
Sensor Signal Conditioning — performs
all necessary functions to calibrate,
compensate for temperature variance,
scale, and linearize the sensor signal.
Analog/Digital Processing — there are
two ways to convert and linearize the
sensor signal. The analog technique
results in an analog solution and provides an analog output. This technique
is inexpensive and fast, but limited to
a maximum of 11- to 16-bit resolution.
Digital is more precise, up to 24-bits,
and provides a digital output at moderate speed.
The bridge excitation linearization
circuit is optimized for bridge pressure
non­linearities with a parabolic shape
1
0
2
3
4
5
6
Bridge Output (mV)
7
8
9
10
PGA309 bridge pressure nonlinearity correction.
(shown above). The linearization circuit
is digitally programmable, but the pure
analog signal conditioning side is handled by the same process as in TI’s
well-known 4-20mA transmitters, such
as XTR105, XTR108 or XTR117. The
heart of the PGA309 is a precision, lowdrift programmable gain instrumentation
amplifier using an auto-zero technique
and includes a programmable fault
monitor and over/underscale limiter. It
also offers a digital temperature compensation circuit. Calibration is carried
out either via a one-wire digital serial
interface or through a two-wire industrystandard connection.
Calibration parameters are stored in
an external nonvolatile memory to
eliminate manual trimming and achieve
long-term stability. An evaluation module, PGA309EVM (see below) includes
software and calibration sheet for easy
evaluation of your sensor + PGA309
combination.
The highly integrated, CMOS PGA309,
available in TSSOP-16, is tailored for
bridge pressure sensors and adds to
TI’s portfolio of highly flexible, lowest
noise amplifier and instrumentation
amplifier solutions that also include the
OPAx227, OPAx132, OPA335, OPA735,
INA326, INA333, INA118 and INA122.
Power
Supply
+ –
VS
VCC
RS232
Customer
Sensor
PRG
VIN
VOUT
GND
PRG
–
PGA309
+
10nF
GND
SDA
SCL
EEPROM
PC
PGA309
PC Interface Board
Temperature
Chamber
PGA309
Sensor Interface Board
–40˚C < Temperature < +125˚C
Pressure
Input
Block diagram of the PGA309EVM module.
Diagnostic, Patient Monitoring and Therapy Applications Guide
34
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
32-Bit Microcontrollers
TMS320C28x™
Get samples and datasheets at: www.ti.com/c2000
• Floating-point and fixed-point
microcontrollers
• Up to 150MIPS or 300MFLOPS
• A mix of 16-bit and 32-bit
instructions
• Unified memory architecture
• Best-in-class compiler efficiency
• Single-cycle 32 x 32-bit multiply
accumulate
• Up to 512KB on-chip Flash and
68KB on-chip SRAM
• 12-bit ADC with 80ns conversion
time and 16 input channels
• Six-channel DMA
• High-resolution PWM with 150ps
accuracy
• PWM microcontrollers with programmable deadband-, phase- or dutycycle control and up to six trip zones
can create any waveform required
• SCI, SPI, I2C, McBSP and CAN ports
• Industrial (–40°C to 85°C) or
extended (–40°C to 125°C) temperature ranges. Fully automotive
qualified.
The C2000™ MCU uses a modified Harvard architecture to unify a high­performance 32-bit core with different on-chip peripherals. An advanced interrupt
management system ensures fast interrupt response. Combined with integrated
Flash and RAM memory blocks, the C2000 MCU provides a powerful single-chip
solution ideal for many embedded applications.
The C28x™ generation of microcontrollers is optimized for delivering the highestperformance control solution with the best time to market.
Flash
Boot
ROM
RAM
PWM
QEP
Memory Bus
CAP
ADC
DMA
Interrupt Management
C28x™ 32-Bit Core
32 x 32-Bit
Multiplier
Pheripheral Bus
Key Features
Atomic
ALU
GPIO
SPI
SCI
I2C
Timers
Real-Time
JTAG
EMIF
32-Bit
Floating-Point
Unit
CAN
McBSP
TMS320C28x™ 32-bit microcontroller block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
35
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Complete Voltage-Output, Programmable Bridge Sensor Signal Conditioner
PGA309
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/PGA309
Key Features
• Ratiometric or absolute voltage
output
• Digitally calibrated via single-wire or
two-wire interface
• Eliminates potentiometer and
trimming
• Low, time-stable total adjusted error
• +2.7V to +5.5V operation
• Packaging: Small TSSOP-16
The PGA309 is a programmable analog signal conditioner designed for bridge
sensors. The analog signal path amplifies the sensor signal and provides digital
calibration for zero, span, zero drift, span drift, and sensor linearization errors with
applied stress (pressure, strain, etc.). The calibration is done via a one-wire digital
serial interface or through a two-wire industry-standard connection. The calibration
parameters are stored in external nonvolatile memory (typically SOT23-5) to eliminate manual trimming and achieve long-term stability.
VS
VEXC
Applications
• Bridge sensors
• Remote 4mA to 20mA transmitters
• Strain, load, weight scales
• Automotive sensors
0
psi
50
Non-Linear
Bridge
Transducer
Linearization
DAC
Analog Sensor Linearization
Fault
Monitor
Ref
Linearization
Circuit
Over/Under
Scale Limiter
Auto-Zero
PGA
Linear VOUT
Analog Signal Conditioning
Digital Temperature
Compensation
*See also the new PGA308
Ext
Temp
Ext Temp
DIGITAL CAL
Int
Temp
Temp
ADC
Control Register
Interface Circuitry
EEPROM
(SOT23-5)
PGA309 functional block diagram.
High-Voltage, High-Current Operational Amplifier
OPA549
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/OPA549
Key Features
• High output current: 8A continuous,
10A peak
• Wide power supply range:
• Single supply: +8V to +60V
• Dual supply: ±4V to ±30V
• Wide output voltage swing
• High slew rate: 9V/µs
• Control reference pin
• Fully protected: thermal shutdown,
adjustable current limit
• Output disable control
• Packaging: 11-pin power package
The OPA549 is a high-voltage, high current op amp designed for driving a wide
variety of loads. It provides low-level signal accuracy and high output voltage and
current. It is internally protected against overtemperature conditions and current
overloads. In addition, the OPA549 provides an accurate, user-selected current
limit. Unlike other designs which use a “power” resistor in series with the output
current path, the OPA549 senses the load indirectly. This allows the current limit to
be adjusted from 0A to 10A with
V+
a resistor/potentiometer, or controlled digitally with a voltageout or current-out DAC.
OPA549
VO
Applications
ILIM
RCL sets the current limit
• Valve, actuator drivers
Ref
value from 0A to 10A.
RCL (Very low power dissipation)
• Synchro, servo drivers
• Test equipment
E/S Pin:
E/S
• Transducer excitation
V–
• Power supplies
Forced Low: Output disabled.
Indicates Low: Thermal shutdown.
OPA549 functional block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
36
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
High-Side Measurement, Bidirectional, Zerø-Drift Current-Shunt Monitor
INA210, INA211, INA212, INA213, INA214
Get samples and datasheets at: www.ti.com/sc/device/PARTnumber
(Replace PARTnumber with INA210, INA211, INA212, INA213 or INA214)
Key Features
• Wide common-mode range:
–0.3 to 26V
• Offset voltage: ±35µV (max) (enables
shunt drops of 10mV full-scale)
• Accurate:
• Gain: ±1% (max)
• Offset drift: 0.05µV/°C (max)
• Gain drift: 25ppm/°C (max)
• Choice of gain range: 50 to 1000V/V
• Supply voltage: +2.7 to +18V
• Quiescent current: 100µA (max)
• Packaging: SC70
The INA21x devices are voltage-output-current shunt monitors that can sense
drops across shunts at common-mode voltages from –0.3 to 26V, independent
of the supply voltage. Five gains are available: 50V/V, 100V/V, 200V/V, 500V/V or
1000V/V. The low offset of the zero-drift series architecture enables current sensing
with maximum drops across the shunt as low as 10mV full-scale.
Reference
Voltage
RSHUNT
3mΩ
Supply
REF
Output
OUT
R1
R3
GND
Load
IN–
Applications
• Medical equipment
• Notebook computers
• Cell phones
• Battery chargers
+2.7V to +26V
CBYPASS
0.01µF
to
0.1µF
IN+
V+
R2
R4
Product
Gain
R3 and R4
R1 and R2
INA210
INA211
INA212
INA213
INA214
200
500
1000
50
100
5kΩ
2kΩ
1kΩ
20kΩ
10kΩ
1MΩ
1MΩ
1MΩ
1MΩ
1MΩ
Typical device configuration options.
Diagnostic, Patient Monitoring and Therapy Applications Guide
37
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers
DRV8402
PWM Motor Driver
24A peak current, 52.5V supplies, 500kHz PWM input
Precision motor control in a complete integrated solution
INA210/11/12/13/14
*Page 37
Current Shunt
Monitor
±35μV (max) offset, 0.05μV/°C (max) drift, 2.7 to 18V supply
voltage
Enables current sensing with maximum drops across the
shunt as low as 10mV full-scale
OPA549 *Page 36
Power Amplifier
8A continuous, 10A peak output current, 9µs slew rate
Wide supply range, thermal protection
OPA564
Power Amplifer
1.5A, 24V, 17MHz, power operational amplifier
Near rail output, current and thermal protection
OPA547, OPA548
OPA567
Power Amplifier
2A output, 150mV of rails with I/O = 2A output swing
Thermal protection, adj. current limit
OPA569
PGA309
*Page 36
Prog. Sensor
Conditioner
Sensor error compensation: span, offset, temp drifts
Complete bridge sensor conditioner
PGA308
THS452X
Low Power FDA
1.14mA quiescent current (typ), +2.5V to 5.5V supply,
4.6nV/√Hz voltage noise
Low power enables high accuracy, low crosstalk in
multichannel options
THS4522,
THS4524
ADS1258
Delta-Sigma ADC
16-channel, 24-bit, 125kSPS, 23.7kSPS/channel
Fastest multi-channel, delta-sigma ADC, measures all
16 inputs in <675µs
ADS1251, ADS1253,
ADS1271
Delta-Sigma ADC
24-bit, 105kSPS, serial interface, SPI w/FSYNC
Designed for multi-channel systems
ADS1278
ADS1298
Delta-Sigma ADC
ECG/EEG AFE
24-bit, 128kSPS, 8 channels, 111dB SNR
24-bit, 8 PGA, 8 ADC, plus RLD and RESP
ADS8318/19
High-Speed SAR
16-bit, 500kSPS, 18mW at 500kSPS power, ±1 LSB INL
Simultaneous measurement, onboard decimation filter
Complete front end, reduction in power and size, increase
reliability
Precision, excellent AC/DC performance
ADS1274,
ADS1278, ADS1284
ADS1271, ADS1274
ADS1294, ADS1296,
ADS1198, ADS1251/58
ADS8326
Low-Power ADC
16-bit, 250kSPS, 2.7V to 5.5V supply,
±1.5 LSB (max) INL
Data Converters
Small package, wide supply range
DAC7564
Quad DAC
Ultra-low glitch, voltage output DAC
Internal low drift reference
DAC7568
Octal DAC
Ultra-low glitch, voltage output DAC
Internal low drift reference
DAC8564
DAC8411
High Resolution DAC
16-bit, low power DAC
Small size, wide supply range
DAC8311, DAC7311
AM3517
Applications
Processor
ARM® Cortex-A8, graphics acelerators, Ethernet, CAN
High performance at handheld power levels
AM3505
MSP430F20xx
Ultra-Low-Power
16-Bit MCU
1KB/2KB Flash, 128B RAM, SPI+I2C
8 ch. 12-bit ADC or 4 ch. 16-bit SD ADC, 4 x 4mm
package
MSP430F22x4
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 512B/1KB RAM, SPI + I2C +
UART/LIN + IrDA
12 ch. 10-bit ADC, 2 op amps
MSP430F23x0
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 1KB/2KB RAM, SPI + I2C + UART/LIN
+ IrDA
Analog comparator, HW multiplier
MSP430F41x
Ultra-Low-Power
16-Bit MCU
4 to 32KB Flash, 256B to 1KB RAM, SVS,
96 segment LCD
Analog comparator
MSP430F43x
Ultra-Low-Power
16-Bit MCU
16 to 32KB Flash, 512B/1KB RAM, SPI + UART, SVS,
160 segment LCD
8 ch. 12-bit ADC, analog comparator
MSP430F44x
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 1KB/2KB RAM, 2x SPI + UART, SVS,
160 segment LCD
8 ch. 12-bit ADC, HW multiplier
MSP430F471xx
Ultra-Low-Power
16-Bit MCU
120KB Flash, 8KB RAM, (4) USCI, DMA, 160 segment
LCD
(7) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
MSP430F54xxA
Ultra-Low-Power
16-Bit MCU
128 to 256KB Flash, 16KB RAM, (4) USCI, PMM, DMA,
temp. sensor
16 ch. 12-bit ADC, analog comparator, RTC, internal
voltage regulator for power optimization
MSP430FG42x0
Ultra-Low-Power
16-Bit MCU
16 to 32KB Flash, 256B RAM, 56 segment LCD
5 ch. 16-bit SD ADC, 12-bit DAC, 2 integrated op amps
MSP430FG43x
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 1KB/2KB RAM, SPI + UART, SVS,
128 segment LCD
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, DMA, 3 op amps
MSP430FG461x
Ultra-Low-Power
16-Bit MCU
92 to 120KB Flash, 4KB/8KB RAM, SPI + I2C +
UART/LIN + IrDA, 160 LCD
12 ch. 12-bit ADC, 2 ch.12-bit DAC, A-comp,
3 op amps, HW multiplier
MSP430FG47x
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 2KB RAM, SPI + I2C + UART/LIN +
IrDA, 128 LCD controller
5 ch. 16-bit SD ADC, 2 ch. 12-bit DAC, A-comp,
2 op amps
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator,
video accelerators
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L137
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™
floating-point DSP core, rich peripheral set including
10/100 Ethernet MAC, LCD controller, USB 2.0 HS OTG,
USB 1.1 full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
OMAP-L138
Stellaris®
LM3S3xxx
Microcontroller
ARM® Cortex-M3, up to 256KB flash, up to
64kB RAM, USB host/device
USB, 10-bit ADC, temperature sensor
Processors
New products are listed in bold red. Preview products are listed in bold blue.
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
38
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Processors (Continued)
TMS320C28x™
*Page 35
32-Bit MCU
Up to 512KB on-chip flash and
68KB on-chip SRAM, up to 150MIPS or 300MFLOPS
Optimized for delivering the highest-performance
control solution with the best time to market
TMS320C5000™
DSP
Power efficient, high performance
Fixed-point DSP with industry’s best combination of
standby and dynamic power consumption
TMS320F28x™
32-Bit MCU
TMS320F2802x/3x
Piccolo™
32-Bit
Microcontroller
32-bit architecture, fixed- or floating-point code, up to
225MIPS operation
Up to 60 MHz C28x™ core with optional control law
accelerator. Up to 128KB Flash, high resolution (150ps)
PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
TMS320F2823x,
TMS320F2833x
TMS320F283x
Delfino,
TMS320F280x
TMS320F2808
32-Bit MCUs
32-bit microcontroller integration, real-time control
performance
With dedicated, high precision peripherals, Piccolo
microcontrollers are the ultimate combination of
performance, integration, size, and low cost. Ideal for
precision sensing and control applications.
I2C, 4 SPI, 2 SCI, 2 CAN
TMS320F283x
Delfino™
32-Bit
Floating-point
Microcontroller
TMS320F2802x/3x
Piccolo,
TMS320F280x
TMS320F28234
32-Bit MCUs
150MIPS, 8KB ROM, 68KB RAM, 256KB Flash, 12-bit
ADC
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point brings
increased performance and quicker development.
Ideal for precision sensing and control applications.
McBSP, 1 SPI, 2 SCI, 2 CAN
TMS320F28015
32-Bit MCUs
60MIPS, 8KB ROM, 12KB RAM, 32KB Flash, 12-bit ADC
I2C, 1 SPI, 1 SCI
TMS320VC5506
DSP
200MHz, dual MAC, very low standby power of
0.12mW
Supported by eXpressDSP™ and many other software
packages and tools
TMS320VC5509A,
TMS320VC5502
SN65HVD1050
CAN Transceiver
–27V to 40V bus-fault protection, meets or exceeds
ISO11898-2
High EMI, low EME
HVD234 is 3.3V
version
SN65HVD3082
RS-485
Transceiver
1/8 unit load — up to 256 nodes on a bus, 15kV ESD
protection
Glitch-free power-up/down bus inputs and outputs
100MIPS, 8KB ROM, 36KB RAM, 128KB Flash, 12-bit
ADC
Up to 300 MHz C28x™ core. Up to 512KB Flash, high
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN, QEP,
external memory bus, DMA.
Interface
Power Management
bq2406x
Battery Charger
Linear 1-cell Li-Ion charger with thermal regulation,
6.5V OVP, temp sense
Good for space-limited designs with need for battery
safety
bq2410x
bq27010
Battery Fuel
Gauge
Li-Ion and Li-Pol battery gas gauge
Reports accurate time-to-empty of battery
bq27200
bq27540
Battery Fuel
Gauge
Li-Ion battery gas gauge with Impedance Track™
fuel-gauge technology
Reports accurate time-to-empty of battery
bq27510
TPS2041B
USB Power
Switches
USB compliant power source, short-circuit protection
Single-chip power-source solution for USB and
memory cards
TPS2550, TPS2061
TPS22902
Load Switch w/
Controller Turn-On
Low on resistance, controlled turn-on, ultra small 0.64mm2
package, quick output discharge
Ultra-small, fully integrated solution
TPS22901, TPS22922,
TPS22924C, TPS22960
TPS22946
Current Limited
Load Switch
Configurable current limit, ultra-small package, 1µA
quiescent current at 1.8 V
Ultra-small, low quiescent current current limited switch
TPS22949,
TPS22945
TPS23750
Power-overEthernet
PoE interface and DC/DC controller in one IC
Transmit power and data to remote devices over
Ethernet cable
TPS23753
TPS23753
Power-overEthernet
PoE with AC adaptor ORing function
Allows 12V adaptor ORing
TPS61042
LED Boost
Converter
Current source with over voltage protection
Simple backlight boost for improved visibility of LCD
TPS61097-33
Boost Converter
with Bypass
Switch
Highly efficient, operates down to 0.3 V; bypass switch;
5nA shutdown current; SOT-23
Super efficient boost, works over entire battery range,
low quiescent current, integrate the bypass switch, small
package
TPS61240
Boost Converter
Input current limit, load disconnect during shutdown
Small, fail save solution
TPS61070
TPS62230
Step-Down
Converter
Up to 90dB PSRR, excellent AC and transient load
regulation
Low noise regulation, 12mm2 solution size
TPS62260
TPS62400
Dual Output
Step-Down
Converter
180° out of phase operation, serial interface
Flexible voltage adjustment for processors and MCUs
TPS62410
TPS62750
Step-Down
Converter
Programmable input current limit, hot plug and reverse
current protection
Supports USB powerde applications and large output
caps
TPS62040
TPS61140
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
39
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Ventilator
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
TPS63000
Buck Boost
Converter
Automatic transition between step down and boost
mode
Produce mid-range voltage out over entire range of
battery
TPS62113
TPS63030
Buck-Boost
Converter
1-A switch, automatic transition between step down
and boost mode
Extending application run time, small solution
TPS61020
TPS717xx
Low-Noise
Single-Channel
LDO
Very high rejection of power-source noise
Low-noise power rails for sensitive analog
components
TPS793xx,
TPS795xx,
TPS799xx
TPS718
Dual-Channel
LDO
Very high rejection of power-source noise
Low-noise power rails for sensitive analog
components
TPS719
TPS780xx
LDO with DVS
Dynamic voltage scaling (DVS) with low IQ 500nA
DVS voltage designed to operate with MSP430™ to
increase power savings
TPS78101
TPS79901
Low-Noise
Single-Channel
LDO
Very high rejection of power source noise
Low-noise power rails for sensitive analog
components
TPS793xx,
TPS795xx
CC1101
Sub-1GHz RF
Transceiver
Wake-on-radio functionality; integrated packet
handling with 64B data FIFOs; high RF flexibility: FSK,
MSK, OOK, 1.2-500kbps; extremely fast PLL turn-on/
hop time
Ideal for low-power systems; any low-end MCU can
be used; backwards compatible with existing systems;
suitable for fast frequency-hopping systems
CC2500
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4
RF Transceiver
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temperature
range; AES-128 security module
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal for
industrial applications; no external processor needed
for secure communication
CC2530
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
MCU, USB 2.0, Flash and RAM in one package; four
flexible power modes for reduced power consumption;
includes CC1101 transceiver frequency synthesizer;
built-in AES-128 encryption coprocessor
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
CC2530/31
Second
Generation
System-on-Chip
Solution for
2.4GHz IEEE
802.15.4/RF4CE/
ZigBee®
Excellent RX sensitivity, low power, easy-to-use
development tools
RF design SOC for quick time to market; provides a
robust and complete ZigBee USB dongle or firmwareupgradable network node
CC2540
2.4 GHz
Bluetooth®
Low Energy
compliant RF
System-on-Chip
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity,
selectivity and blocking performance
Fast-to-market Bluetooth® low energy compliant
solution
WL1271
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
Single-chip 802.11b/g/n WLAN and Bluetooth®
solution using TI’s digital radio processor technology
using a single antenna.
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
Sophisticated low-power technology ideal for battery operated
solutions; coexistence features enable simultaneous WLAN
and Bluetooth® operations ; supports ANT+ standard.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
ZigBee stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings; excellent selectivity and blocking
performance
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery operated systems; excellent
coexistence with Bluetooth® technology and Wi-Fi.
RF ICs
RF Transceivers
RF Systems-on-Chip
CC2560
CC2510/11
WL1273
CC2510, CC2511
CC2590/91,
CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Second
Generation
Z-Stack™
Network Processor
New products are listed in bold red. Preview products are listed in bold blue.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
40
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
Continuous positive airway pressure
(CPAP) is a method of respiratory ventilation used mainly for the treatment
of sleep apnea at home. Sleep apnea
occurs during sleep when the muscles
tend to relax naturally, causing the
upper airway to narrow. This narrowing
reduces the amount of oxygen in the
blood and causes arousal from sleep.
Pressure sensors play an important role
in respiration equipment. In addition to
converting physical values such as airway pressure and flow into a differen­tial
signal, air and flow sensors generate
signals that help the microprocessor
regulate the motor to adjust/maintain
the desired pressure as the person
inhales or exhales.
The sensors are very cost-effective.
Large offset and offset drift cause the
signals to be off-scale, temperaturevariant and nonlinear. Amplifiers with
low offset voltage and drift over time
and temperature are ideal for signal
conditioning.
DC motor control can be accomplished
by monitoring at least two of the three
current phases, along with the DC bus
voltage feeding the motor drive bridge.
For phase currents, two approaches
can be used: high-side or low-side.
Direct phase measurement, or highside, requires high-speed difference
amplifiers or current-shunt monitors
and is generally more accurate. The
low-side approach takes measurements near the half-bridge ground
connection and uses simpler amplifiers
that can be less costly but also less
precise. The DC motor is driven by
discrete FETs.
Devices in TI’s DRV family offer an
integrated driver and bridge with
12-V Bus
Pump
Humidity
Temperature
Flow Rate
Sensor Pressure
Pump
High-Side
Monitor Option
Low-Side
Monitor Option
Humidifier
Blower
REF
Water Level
Sensor
Buffer
Optional
3Ø Current
Measurement
Feedback and Monitors
Clock
REF
ADC
1 2
6 7
1 3234 45 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
1 2
6 7
1 323445 5
6 87 8
AM/PM
AM
/PM
mg/dL
mg
/dL
LCD
ADC
DAC
ADC
Backlight
ADC
Processor
Core and
I/O Power
MOSFET
Driver
Touch Screen
Control
Audio
DAC
Audio Amp
RS-232
DC Measure
ADC
Logic
AC Line
System
Power
FLASH/
EPROM
Isolated AC/DC
Supply With
Green Mode
SDRAM
Level Shift
Plug
Audio
Alerts
Hot Swap
Temp Sense
Fan Control
LEGEND
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
CPAP system block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
41
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
thermal protection and are smaller,
more precise and much more efficient.
The microprocessor performs multiple
operations. These operations include
sampling the pressure signals and
computing a desired airway pressure
and flow level to communicate with the
motor. To achieve these operations
efficiently and in real-time, a high-speed,
low-power, highly-integrated micro­
processor should be used. A highquality DSP can be used for such
applications and will also provide the
patient ultra-quiet operation.
High-Performance 32-Bit Microcontroller for CPAP Machines
TMS320C2000™
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/c2000
Continuous Positive Airway Pressure
(CPAP) machines are an effective means
of preventing intubation, decreasing
mortality in patients with acute respiratory failure, helping patients with sleep
apnea and reducing chronic respiratory
failure.
Designers of CPAP machines are concerned with the efficiency of the motor
that drives the continuous airflow to
the patient, and try to reduce the number of components on the system
board for lower cost, easier development and quicker time to market.
CPAP systems designers value the
TMS320C2000 for its exceptional
capabilities, including:
1. TMS320C2000 32-bit microcontrol­
lers are high-performance, low-cost
Flash
ICs that control motor speed,
position and torque in real time. If
necessary these controllers can
even provide the processing power
for executing highly sophisticated
position and speed estimation algorithms to control the motor using
data from resolver, encoder and
hall-effect sensor.
2. These high-performance controllers
not only provide accurate control of
the motor but can also provide
additional MIPS and peripheral
integration to act as the host MCU.
These ICs can perform up to 150MIPS
and have a high level of peripheral
integration with on-chip flash, a
12-bit, 16-channel ADC with up to
12.5MSPS performance and multiple
Boot
ROM
RAM
GPIO pins so designers can use a
single controller for a lower cost.
3. The C2000™ platform has a free
extensive motor control library
(www.ti.com/c2000appsw) that can
help a developer get the software
framework necessary to control
either a single-phase or three-phase
BLDC motor. In addition, the
C-compiler efficiency eliminates the
need for most assembly coding.
Key Features
• Real-time control reducing overall
system cost
• Scalable controller offers from sub$2 for 150MIPS
• Software and tool compatibility
across full family
PWM
QEP
Memory Bus
Host MCU
• LCD
CAP
• I/O
• Store Patient Data
DMA
Interrupt Management
C28x™ 32-Bit Core
32 x 32-Bit
Multiplier
Pheripheral Bus
ADC
Atomic
ALU
GPIO
• Speed Control
SPI
32-Bit
Floating-Point
Unit
Patient
Monitoring
• PWM
SCI
• ADC for Back EMF
I2C
Timers
Real-Time
JTAG
EMIF
• Sometimes Sensored
Driver
+
Inverter
Compressor:
Brushless
or
DC Motor
CAN
McBSP
TMS320C2000™ 32-bit MCU in simplified patient
monitoring system.
TMS320C2000™ 32-bit MCU block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
42
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
Key Features (Continued)
• On-chip programmable flash
• C-compiler efficiency eliminates the
need for most assembly coding
• 10- or 12-bit ADCs with up to 16
channels and 12.5MSPS
• Independent or complementary
PWM with deadband
• Independent duty-cycle or phase
control
• 150ps high-resolution PWM
• Encoder interfaces and event
capture inputs
• CAN 2.0B, SCI, SPI, and I2C port
interfaces
• Long product life cycle assures
supply continuity
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
AM3517
TMS320C2000™
*Page 42
TMS320F2802x/3x
Piccolo™
Applications
Processor
High-Performance
Microcontroller
32-Bit
Microcontroller
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
High performance at handheld power levels
32-bit, up to 150MIPS, up to 12.5MSPS
High-performance, low cost
Up to 60MHz C28x™ core with optional control law
accelerator. Up to 128KB Flash, high resolution (150ps)
PWMs, 4.6MSPS ADC, CAN/LIN, QEP.
With dedicated, high precision peripherals, Piccolo
microcontrollers are the ultimate combination of
performance, integration, size, and low cost. Ideal for
precision sensing and control applications.
TMS320F283x
Delfino,
TMS320F280x
Delfino brings floating point and unparalleled
performance to MCUs. Native floating point brings
increased performance and quicker development.
Ideal for precision sensing and control applications.
TMS320F2802x/3x
Piccolo,
TMS320F280x
AM3505
TMS320F28015
High-Speed
Microcontroller
32-bit digital signal controller with flash
TMS320F2812
High-Speed
Microcontroller
32-bit digital signal controller with flash
TMS320F28232
Digital Signal
Controller
High-performance static CMOS technology. Highly
integrated, high-performance solutions for demanding
control applications
TMS320F28234
Digital Signal
Controller
High-performance static CMOS technology. Highly
integrated, high-performance solutions for demanding
control applications
TMS320F28235
Digital Signal
Controller
TMS320F283x
Delfino™
32-Bit
Floating-point
Microcontroller
High-performance static CMOS technology. Highly
integrated, high-performance solutions for demanding
control applications
Up to 300 MHz C28x™ core. Up to 512KB Flash, high
resolution (150ps) PWMs, 12MSPS ADC, CAN/LIN, QEP,
external memory bus, DMA.
TMS320F28335
Digital Signal
Controller
High-performance static CMOS technology. Highly
integrated, high-performance solutions for demanding
control applications
TMS320VC5509A
Low-Power DSP
Up to 200MHz, dual MAC, 256KB RAM/64KB ROM, USB
2.0 full speed, MMC/SD, 10-bit ADC
Power efficient; large on-chip memory, rich peripheral
set allows for various portable connectivity; C55x™
code compatibility
C550x DSP
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L137
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low
system cost and maximum flexibility for connectivity,
GUI and high-level OS options. Extends product battery
life by providing greater than 60% power reduction
over existing solutions in the market.
OMAP-L138
Stellaris®
LM3S3xxx
Microcontroller
ARM® Cortex-M3, up to 256KB flash, up to 64kB RAM,
USB host/device
USB, 10-bit ADC, temperature sensor
ADS1258
Delta-Sigma ADC
16-channel, 24-bit, 125kSPS, 23.7kSPS/channel
Fastest multi-channel, delta-sigma ADC, measures all
16 inputs in <675μs
ADS1158, ADS1248
ADS7952
SAR ADC
12-bit, 1MSPS, 70dB SNR, 11.5mW power
Zero latency, ideal for multi-channel systems
ADS7951, ADS7953
Data Converters
ADS8317
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
Excellent linearity, micropower, high speed
ADS8422
ADS8318
SAR ADC
16-bit, 500kSPS, 18mW (typ) power, 95.5dB SNR,
±1 LSB (max) INL
Zero latency, serial interface, low power
ADS8519, ADS8321
ADS8326
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
Low noise, low power, high speed
ADS8325
ADS8331/32
SAR ADC
16-bit, 500kSPS, 4/8 channels, with serial interface
ADS8342
ADS8201
Low-Power SAR
ADC
8 channel, 12-bit, 100kSPS, 1.32mW power consumption
at 100kSPS
Mux out feature can be used to reduce system part
count and overall cost
Full on-chip data acquisition system
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
ADS7870
New products are listed in bold red.
43
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Data Converters (Continued)
ADS8472
SAR ADC
16-bit, 1MSPS, ±0.4LSB (typ) INL
Zero latency, low power
TLV320DAC3120
Low-Power
Audio DAC
Mono DAC with 2.5W mono Class-D speaker amplifier;
miniDSP for audio processing
Longer battery life, better audio quality, lower cost
TLV320DAC3101
TLV320DAC32
Audio DAC
Low-power stereo DAC, 4 outputs, HP/speaker amplifier,
3D effects
TSC2000
Touch-Screen
Controller
4-wire programmable touch-screen controller with
8-/10-/12-bit 125kHz ADC and SPI interface
TSC2003
Touch-Screen
Controller
4-wire touch-screen controller
TSC2006
Touch-Screen
Controller
Nano-power touch-screen controller with SPI serial
interface
TSC2007
Touch-Screen
Controller
Nano-power touch-screen controller with I2C serial
interface
TSC2046
Touch-Screen
Controller
4-wire touch-screen controller with low-voltage
digital I/O
TSC2200
Touch-Screen
Controller
Programmable 4-wire touch-screen controller with
12-bit 125kHz ADC and keypad interface
REF3030
Series Voltage
3.0V, 50ppm/°C, 50µA in SOT23-3
Low power, small size
REF2930
REF3130
Series Voltage
20ppm/°C max, 100µA, SOT23-3
Precision, low power, small size
REF3330
CDCE913
Programmable
1-PLL VCXO
Clock Synthesizer
with 2.5 or 3.3V
LVCMOS Outputs
Input clock: X-tal (8 to 32MHz) or LVCMOS up to 150MHz;
VCXO input with ±150ppm (typ) pulling range; output
frequencies up to 230MHz; three low-jitter, low-skew,
high-performance LVCMOS output fan-out buffers
Wide input/output frequency range supports wide
frequency ratio for audio/video clocking; easy
frequency synchronization; fractional PLL enables zero
PPM clocking generation; integrated fan-out buffers
reduce clock distribution cost
CDCEL913
Programmable
1-PLL VCXO
Clock Synthesizer
with 1.8V
LVCMOS Outputs
Input clock: X-tal (8 to 32MHz) or LVCMOS up to 150MHz;
VCXO input with ±150ppm (typ) pulling range; output
frequencies up to 230MHz; three low-jitter, low-skew,
high-performance LVCMOS output fan-out buffers
Wide input/output frequency range supports wide
frequency ratio for audio/video clocking; easy
frequency synchronization; fractional PLL enables zero
PPM clocking generation; integrated fan-out buffers
reduce clock distribution cost
ISO721
Single-Channel,
100Mbps Digital
Isolator
Silicon-integrated SiO2 dielectric capacitor; 0 to 150Mbps
and DC signal pass with fail-safe; 1ns skew, 1ns jitter,
1ns pulse distortion; input threshold; noise filter; high
magnetic immunity (1E6 > inductive)
Proven reliability of SiO2 dielectric, stable over tem­
perature and moisture; lowest skew, jitter and pulse
width distortion; filters noisy signals before entering
system; high immunity for noisy environments
ISO7221C
Dual-Channel,
1/1, 25Mbps
Digital Isolator
Silicon-integrated SiO2 dielectric capacitor; 0 to 150Mbps
and DC signal pass with fail-safe; 1ns skew, 1ns jitter,
1ns pulse distortion; input threshold; noise filter; high
magnetic immunity (1E6 > inductive)
Proven reliability of SiO2 dielectric, stable over tem­
perature and moisture; lowest skew, jitter and pulse
width distortion; filters noisy signals before entering
system; high immunity for noisy environments
ISO7231C
Triple-Channel,
2/1, 25Mbps
Digital Isolator
Silicon-integrated SiO2 dielectric capacitor; 0 to 150Mbps
and DC signal pass with fail-safe; 1ns skew, 1ns jitter,
1ns pulse distortion; input threshold; noise filter; high
magnetic immunity (1E6 > inductive)
Proven reliability of SiO2 dielectric, stable over tem­
perature and moisture; lowest skew, jitter and pulse
width distortion; filters noisy signals before entering
system; high immunity for noisy environments
ISO7241M
Quad-Channel,
3/1, 150Mbps
Digital Isolator
Silicon-integrated SiO2 dielectric capacitor; 0 to 150Mbps
and DC signal pass with fail-safe; 1ns skew, 1ns jitter,
1ns pulse distortion; input threshold; noise filter; high
magnetic immunity (1E6 > inductive)
Proven reliability of SiO2 dielectric, stable over tem­
perature and moisture; lowest skew, jitter and pulse
width distortion; filters noisy signals before entering
system; high immunity for noisy environments
OPA4376
Precision Op Amp
Quad, 5.5MHz GBW, 2V/µs
— slew rate, 0.95mA/ch IQ,
76dB CMRR, 7.5nV/√Hz noise
Precision, low power
OPA4727, OPA2376
INA169
Current-Shunt
Monitor
2.7V to 60V, 60µA (typ) IQ, unipolar, high-side current
measurement
High speed, small size
INA168, INA139
INA170
Current-Shunt
Monitor
2.7V to 40V supply, 2.7V to 60V common-mode voltage,
75µA (typ) IQ, bidirectional
Low power, current output
INA193, INA138
INA210
Current-Shunt
Monitor
–0.3V to 26V common-mode range, ±35µV offset,
100µA IQ, 0.5µV/°C (max) offset drift
Voltage output, bidirectional, zero-drift series
INA138, INA193
INA332
Instrumentation
Amp
0.07%, 2ppm/°C, G = 5 gain accuracy, 73dB CMRR,
0.5pA IB, 490µA (max/ch) IQ
Single or bipolar operation, low noise
INA326, INA338
INA333
Instrumentation
Amp
25μV (max) offset, 50nV/°C drift, 50 μA (typ) Iq
Best offset/noise combination, supply down to 1.8V,
low power
INA321, INA118
References
Clocking
Interface
Amplifiers
New products are listed in bold red.
view more system block diagram compatible products, visit www.ti.com/medical
To
Diagnostic, Patient Monitoring and Therapy Applications Guide
44
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers (Continued)
OPA333
OPA2365
Precision Op
Amp
Precision Op Amp
1.8V min supply, 0.017mA/ch (max), 10μV offset (max),
0.05 μV/°C drift (max)
Dual, zero crossover,
0.0006% THD+N, 100dB CMRR,
—
RRIO, 4.5nV/√Hz noise, 50MHz GBW, 200µV input offset
OPA376
Precision Op Amp
TLC2264
Op Amp
7.5nV/√Hz noise, 760µA(typ)/ch Iq, 5µV (typ) offset, input
EMI filter, RRO
—
Quad, 12nV/√Hz (typ) noise, 1pA bias current, 500µA
(max) IQ, RRO
THS452X
Low power FDA
+2.5V to 5.5V supply, 1.14mA (typ) quiescent current,
4.6nV/√Hz voltage noise
TPA2006D1
Analog-Input
Class-D Amp
1.45W mono, filter-free Class D, 1.8V shutdown
TPA2010D1
Analog-Input
Class-D Amp
TPA2013D1
Zero drift, high precision, low power, EMI input
Superior performance, excellent for driving singlesupply ADCs
OPA335, OPA378,
OPA330
OPA2333
Low noise, low power, low input bias
OPA340, OPA337
Single or split supply, low noise
TLC2274
Low power, low noise enables high accuracy
THS4522, THS4524
2.5W mono, fully differential, filter-free Class D, in WCSP
Loud audio, long battery life, small package size
TPA2031D1
Analog-Input
Class-D Amp
2.7W constant output power, mono, Class D, integrated
boost converter
Louder audio at low battery levels
TPA2014D1
TPA2016D2
Analog-Input
Class-D Amp
1.7W stereo, Class D with dynamic range compression
and automatic gain control
TPA6205A1
Class-AB Audio
Amp
1.25W mono, fully differential, Class AB, 1.8V shutdown
Loud audio, low cost
TPA6204A1
TPA6211A1
Class-AB Audio
Amp
3.1W mono, fully differential, Class AB
Loud audio
Power Management
TPS2550
USB Power
Switch
Adjustable current-limited power-distribution switch
Allows custom current set limit for different designs
TPS2811
MOSFET Driver
Inverting dual high-speed MOSFET drivers with internal
regulator
Saves solution space
TPS3103E12
Supervisory
Circuit
Ultra-low-supply-current/supply-voltage supervisory
circuit
Saves battery power
TPS3813I50
Supervisory
Circuit
Supervisor with programmable watchdog window
Allows custom time intervals
TPS40077
DC/DC Controller
Wide-input (8V to 40V), up to 1MHz-frequency
synchronous buck controller, source only
Higher frequency requires smaller inductor and input
capacitor
TPS40200
DC/DC Controller
4.5V to 52V input non-synchronous buck DC/DC
controller
Very wide input allows wider range of solutions
TPS5410
DC/DC Converter
5.5V to 36V input, 1A step-down converter
Wide input range provides for mulitple input solutions
TPS54310
DC/DC Converter
Low-input-voltage, 3A synchronous buck converter with
adjustable output voltage
Higher efficiency with synchronous solution
TPS54350
DC/DC Converter
4.5 to 20VIN, 3A DC/DC with integrated switch FET, sync
pin, enable
Eliminate beat noise/ceramic caps/FPGA/integration
TPS54550
TPS61050
White LED Driver
1.2A high-power white LED driver with I2C-compatible
interface
Provides I2C control
TPS61058
TPS61093
OLED Boost
Converter
Wide VIN range, input-output disconnect
Flexible, fail safe solution
TPS61080
TPS61140
White LED Driver
Dual, 2x 27V, 700mA switch, 1.2MHz boost converter
with single-inductor white LED and OLED driver
High switching frequency requires smaller inductor
and input capacitor
TPS61160
White LED Driver
White LED driver with digital and PWM brightness
control in 2mm x 2mm package
Will allow stepped brightness adjustment
TPS61061
TPS62110
Step-Down
Converter
3.1V to 17V VIN, 1.5-A conversion, synchronization pin, low
battery indicator, power save mode
Very low noise/high efficiency
TPS62050
TPS62230
Step-Down
Converter
Up to 90dB PSRR, excellent AC and transient load
regulation
Low noise regulation, 12mm2 solution size
TPS62260
TPS62750
Step-Down
Converter
Programmable input current limit, hot plug and reverse
current protection
Supports USB powerde applications and large output
caps
TPS62040
TPS65120
DC/DC Converter
5V/20mA (I/O), 4-ch high-accuracy multi-converter
w/3.3V LDO for LCD bias
Complete solution in one package
TPS65123
DC/DC Converter
5V/20mA (I/O), 4-ch high-accuracy multi-converter w/o
LDO for LCD bias
Complete solution in one package
New products are listed in bold red.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
45
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Continuous Positive Airway Pressure (CPAP)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
TPS65124
DC/DC Converter
5V/20mA (I/O), 4-ch high-accuracy multi-converter w/o
LDO and w/programmable seq. for LCD bias
Complete solution in one package
TPS65130
DC/DC Converter
800mA boost current w/positive and negative (dual)
output for OLED and CCD sensor
Provides smaller solution size
TPS73025
LDO
Single-output LDO, 200mA, fixed (2.5V), high PSRR,
low noise
High PSRR requires less noise filtering in sensitive
applications
TPS73028
LDO
Single-output LDO, 200mA, fixed (2.8V), high PSRR,
low noise
High PSRR requires less noise filtering in sensitive
applications
TPS75103
LDO
Low-dropout, two-bank LED driver with PWM
brightness control
Will allow stepped brightness adjustment
TPS75105
LDO
Low-dropout, two-bank LED driver with PWM
brightness control
Will allow stepped brightness adjustment
TPS767D301
LDO
Dual-output LDO voltage regulator
Core and I/O voltage rails in one LDO
TPS79718
LDO
Single-output LDO, 50mA, fixed (1.8V), low quiescent
current, power-good output
Better battery life with PG signal for the processor
TPS79730
LDO
Single-output LDO, 50mA, fixed (3.0V), low quiescent
current, power-good output
Better battery life with PG signal for the processor
.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
46
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Dialysis Machine
Satisfying Safety Criteria
A dialysis machine is an artificial kidney
that treats the blood of people who
have inadequate kidney function.
Dialysis machines are processor-based
and incorporate electromechanically
controlled extracorporeal blood paths
that leverage pumps and semi-­
permeable dialyzer membranes to filter
the person’s blood.
From an operational perspective,
­dialysis equipment must meet specific
safety criteria. One of these criteria is
single-fault tolerance, which means no
single point-of-failure in the pumps,
motors, tubes or electronics will
endanger the patient. To achieve
µController
A safe mode of operation involves
disabling the arterial blood pump and
clamping the venous line to prevent
5V
Bus
12 V
Bus
5V
Bus
12 V
Bus
Card Power
Core I/O Power
24 V
Bus
AC Line
SVS/
Watchdog
Sensor Control Board
AC/DC
Supply
Main Power Supply
Motor/Pump Driver
EEPROM
ADC
Venous Pressure
Card
Power
Transducer
Core I/O
Power
µController
Detector
Vent Valve
Level Sense
Card Power
Core I/O
Power
Arterial Pressure
Clock
VCO
Line Clamp
Card
Power
Reference
Clock
µController
Pumps
and
Pump Motors
Clock
Card Power Reference
ADC
Pump
Buffers
Other Sensor
Control Cards
Plug
Fan
Driver
Temperature
Sensor
Buffers
Keypad
Clock
EEPROM
LED Driver
LCD Display
LCD
Backlight
Main System Board
Audio Alerts
single-point tolerance, there must be
several redundant components and
circuits, as well as “watchdog” managed-disengage system mechanisms.
ADC
ADC
ADC
ADC
Transducer
Clock
ADC
Reference
Card
Power
µController
RPM
Core I/O
Power
ADC
ADC
Pump
Leak and Color Detection
LEGEND
Processor
Interface
RF/IF
Amplifier
Product Availability and Design Disclaimer – The system block
diagram depicted above and the devices recommended are
designed in this manner as a reference. Please contact your
local TI sales office or distributor for system design specifics
and product availability.
Logic
Power
ADC/DAC
Clocks
Other
Human Arm
Dialysis machine system block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
47
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Dialysis Machine
unsafe blood from flowing to the
patient. Both active and passive components, such as control devices,
sensors, motors, heaters, pumps and
valve drivers, are needed for this type
of functionality.
the response across the entire system
instead of reacting to random stimuli.
The ADCs used must provide high
reliability, good noise immunity (since
there are motors and pumps in the
system) and good precision.
The typical electronic circuits in a ­dialysis
machine include the sensor control
board, arterial and venous control card,
and motor and pump drivers.
Arterial and Venous Control Card
Sensor Control Board
Sensor control boards contain analogto-digital converters (ADCs), precision
references, clocks and VCOs, as well
as instrumentation or operation amplifiers. Although these circuits need to
respond quickly, they are often geared
more toward precision than high speed
to satisfy the need to verify a measure­
ment or alarm signal and coordinate
These portions of a system may include
functions like arterial and venous
­pressure sensors, blood pumps, line
clamps, level sensors, blood detection
sensors and various monitoring and
control features.
TI’s C2000™ 32-bit microcontrollers
are a great fit for motor-control and
industrial-sensor applications. These
MCUs provide drive and diagnostic
capabilities, while allowing the implementation of RPM and motor coil current sensing. They also offer the ability
to read pressure transducers and can
support required system redundancy
at a minimal cost.
Motor and Pump Drivers
There are a number of motors, pumps,
valves and heaters in a dialysis
machine. Each of these may need
a specific drive circuit, while some
can be driven directly by a C2xxx
controller. Selecting the appropriate
digital-to-analog converter (DAC) and
drive amplifier is important to motor/
pump control and life expectancy.
Driving any of the values or motors too
hard, with signals that are to noisy, can
cause them to run hot and degrade
quickly. This can negatively affect the
patient’s comfort while connected to
the machine.
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
Applications
Processor
Applications
Processor
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
High performance at handheld power levels
AM3505
ARM® Cortex-A8, C64x+™, graphics accelerator, video
accelerators
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L137
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
OMAP-L138
Stellaris®
LM3S3xxx
Microcontroller
ARM® Cortex-M3, up to 256KB flash, up to 64kB RAM,
USB host/device
USB, 10-bit ADC, temperature sensor
TMS320F28022
Low-End 32-Bit
MCU with Analog
Integration
Small packages, integration, real-time control
performance
System cost optimization
F2802x Piccolo™
Series
TMS320F28032
Mid-End 32-Bit
MCU with Analog
Integration
Integration, up to 128KB Flash, control-law accelerator,
real-time control performance
System cost optimization, performance at lower
power
F2803x Piccolo
Series
TMS320F2808
Mid-End 32-Bit
MCU
Integration, 12 derivatives pin-to-pin compatible from
60MHz to 100Hz, real-time control performance
System cost optimization, scalability in design
F280x derivatives
series
TMS320F28234
High-End 32-Bit
Fixed-Point MCU
Integration, performances, pin-to-pin compatibility with
floating point
Room for performance and application evolution
F28232, F28235
TMS320F28334
High-End 32-Bit
Floating-Point MCU
Integration, performances, unique pin-to-pin compatibility
with fixed point, supports both fixed and floating
Ease of development, room for performance and
software evolution
F28332, F28335
AM3517
OMAP3530
Data Converters
ADS1115
Delta-Sigma ADC
16 bit, 860SPS, 4 SE, 2 Diff input, PGA, MUX, Comparator,
VREF
Smallest 16-bit ADC – 2.0 x 1.5 x .04 mm leadless
QFN pkg – reduces system size and component count
ADS1013/14/15/
ADS1113/14/
ADS1251
Delta-Sigma ADC
24-bit, 20kSPS, 7.5mW power, 1.5ppm low noise
Precision, wide dynamic range
ADS1252/53/58
ADS7866
SAR ADC, Serial
1.2V, 12-bit, 200kSPS (max), 85dB SFDR
Very small, low power
ADS7924
Micropower SAR
ADC
12-bit, 100kSPS, 4 channel, ≤1µA power down current,
I2C interface, QFN package
Intelleigent system power management and self
monitoring
ADS7951
SAR ADC
12-bit, 8-channel, 1MSPS, SPI interface w/threshold
alarms, QFN package
Low power, small package, and excellent
performance
ADS7955, ADS7959
ADS8201
Low-Power SAR
ADC
8 channel, 12-bit, 100kSPS, 1.32mW power consumption
at 100kSPS
Full on-chip data acquisition system
ADS7870
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
New products are listed in bold red.
48
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Dialysis Machine
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Data Converters (Continued)
ADS8326
SAR ADC
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB (max) INL,
SE input
Low power, small package, and wide supply range
ADS8317
DAC8806
Multiplying DAC
14-bit, 0.5µs settling time, 2MSPS update rate, parallel
interface, 2.7V to 5.5V supply
Low noise, low power
DAC7742
DAC8811
Multiplying DAC
16-bit, serial input, 0.5µs settling time, 2MSPS update
rate, 0.025mW power
Low noise, low power
DAC7811, DAC8801
DAC8820
Multiplying DAC
16-bit, parallel input, 0.5µs settling time, 2MSPS update
rate, 0.025mW power, current output
Parallel interface for high-speed communications
DAC7541, DAC8806
INA118
Instrumentation Amp
110dB CMRR, 5nA (max) bias current, 50μV (max) offset
Wide BW at high gains, ±1.35V to ±18V supply
INA128
INA126
Instrumentation Amp
175µA/ch supply, 3µV/°C (max) drift, 250µV (max) offset
Precision low power, ±1.35V to ±8V supply
INA2126 (dual)
INA333
Instrumentation Amp
25μV (max) offset, 50nV/°C drift, 50μA (typ) Iq
Best offset/noise combination, supply down to 1.8V,
low power
INA321, INA326
OPA141
Precision Op Amp
10MHz, 6.5nV/√Hz, ±4.5V to ±18V, 1.8mA typical, FET input:
IB = 20pA max
—
1.1nV/√Hz noise at 1kHz, ±2.25V to ±18V supply, 80MHz BW
—
Dual, 2nV/√Hz input noise, 1.2mV input offset, 240MHz
GBWP, 90mA output, 4.8mA/ch IQ, +5V to +12V supply
1.8V (min) VS, 0.017mA (max)/ch IQ, Vos 10μA (max), Vos
drift 0.05 μV/°C (max)
Zero crossover,
0.0006% THD+N, 100dB CMRR, RRIO,
—
4.5nV/√Hz noise, 50MHz GBW, 200µV input offset
Common mode voltage range includes GND
OPA827
Superior performance, excellent for driving singlesupply ADCs
Amplifiers
Unity gain stable, RRO, wide supply range
OPA227
High speed, wide input and output voltage swing,
excellent DC accuracy
Zero drift, high precision, low power, EMI input
OPA2690, OPA842
OPA211
Precision Op Amp
OPA2822
High-Speed Amp
OPA333
Precision Op Amp
OPA365
Op Amp
OPA695
High-Speed Amp
1400MHz BW (G = +2), 4300V/µs slew rate, 129mW
power, ±4.2V output voltage swing
Wide bandwidth, current feedback, low power,
excellent accuracy
OPA847, OPA691
THS4521
Low Power FDA
1.14mA (typ) quiescent current, fully differential rail-torail output, negative rail input
Low power, fully differential
THS4522, THS4524
TPA2006D1
Analog-Input
Class-D Amp
1.45W mono, filter-free Class D, 1.8V shutdown
TPA2010D1
Analog-Input
Class-D Amp
2.5W mono, fully differential, filter-free Class D, in WCSP
Loud audio, long battery life, small package size
TPA2031D1
TPA2013D1
Analog-Input
Class-D Amp
2.7W constant output power, mono, Class D, integrated
boost converter
Louder audio at low battery levels
TPA2014D1
TPA6205A1
Class-AB Audio
Amp
1.25W mono, fully differential, Class AB, 1.8V shutdown
Loud audio, low cost
TPA751
TPA6211A1
Class-AB Audio
Amp
3.1W mono, fully differential, Class AB
Loud audio
Wide VIN buck controller with selectable switching
frequency
Buck controller with 5-/12-/24-input voltage ranges
3A switcher with intregrated FETS
Allows designer to select best combination of input
voltage and switching frequency
Covers most common intermediate voltage buses
Provides controller and FETS in one package for
best solution size
Eliminate beat noise/ceramic caps/FPGA/integration
TPS54550
Allows ultra-small two- or three-cell alkaline or onecell Li-Ion operation
Simple backlight boost for improved visibility of LCD
TPS61140
OPA335, OPA378,
OPA330
OPA333, OPA211
Power Management
TPS40054
DC/DC Controller
TPS40077
TPS54310
DC/DC Controller
DC/DC Controller
TPS54350
DC/DC Converter
TPS61040
White LED Driver
TPS61042
LED Boost
Converter
Linear Charge
Management
Linear Charge
Management
Linear Charge
Management
Linear Charge
Management
LDO
TPS65010
TPS65020
TPS65023
TPS75003
TPS72501
4.5 to 20VIN 3A DC/DC with integrated switch FET, sync
pin, enable
28V boost converter for white-LED supply
Current source with overvoltage protection
Multi-channel 1-cell Li-Ion power management IC, USB/
AC charger, 2 DC/DCs, 2 LDOs, I2C interface
6-channel power management IC with 3 DC/DCs, 3 LDOs,
I2C interface and dynamic voltage scaling
6-channel power management IC with 3 DC/DCs, 3 LDOs,
I2C interface and DVS, optimized for DaVinci™ DSPs
Integrated triple-supply power management IC for Xilinx®
Spartan®
Single-output LDO, 1.0A, adjustable (1.22V to 5.5V), any
cap, low-input voltage, integrated SVS
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
Provides complete solution in one package
Provides complete solution in one package
Provides complete DaVinci solution in one package
Provides all three rails in one package
Combines the LDO and SVS function in one small
package to save space
TPS726xx family
New products are listed in bold red.
49
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Infusion Pump
Infusion pumps are an effective pathway to deliver fluid, blood, and medication to a patient's vital organs. Since
the entire blood supply within a human
body circulates within 60 seconds,
substances introduced into the circulatory system are distributed rapidly.
An infusion device typically consists
of three major components: the fluid
reservoir, a catheter system for transferring fluids into the body and a
device that combines electronics with
a mechanism to generate and regulate
flow. Regulated drug concentration
in the body is needed to achieve and
maintain a desired result, especially if
prolonged under-infusion or over-infusion takes place. While under-infusion
may not require sufficient therapy,
over-infusion can produce more serious
toxic side effects.
interface, smart and real-time physio­
logical processing and wired and wireless connectivity options for patient
monitoring and data logging applications provide an additional level of
safety by quickly detecting compli­
cations and generating an alarm.
The infusion of drugs requires high
flow-rate accuracy and flow uniformity.
Sensors can be used to count the
­number of drops passing through the
drip chamber. Sensors can also provide
flow feedback for automatic rate
adjustment and detect downstream
occlusions below the pumping mechanism. However, flow-rate accuracy
remains limited by the rate and viscosity of the drip as well as improper angulation if in motion. Flow uniformity can
also suffer at low flow rates from the
discrete nature of the drop detector.
One alternative to the drop sensor is a
volumetric metering chamber. A pump
with a stepper or servo-controlled DC
motor can be used to provide the driving force for the fluid by mechanized
displacement of the contents in the
volumetric chamber. The stepping
resolution, along with chamber elasticity, can influence flow uniformity. When
the volume is not uniform over the
mechanism’s cycle, software control
can be used to compensate for the
variation.
Despite these limitations, a processor
with an advanced graphical user
Clock
Backlight
Keypad
Logic
REF
Touch Screen
Control
ADC
Pump
DAC
Sensor
Temp
Sense
Pump
Pump
Audio Alarms
or Instructions
Audio Amp
Processor
Pump
Driver
Wireless
Wired
ADC
Sensor
Common Interfaces
AC Line
Isolated AC/DC
Supply
(Green Mode)
Battery
Charger
Battery
Protection
Fuel
Gauge
System
Power
Memory
Power
FLASH/
EPROM
Plug
Level Shift
SDRAM
Core and
I/O Power
Low Noise Power
Interface
Protection
LEGEND
Processor
Interface
RF/IF
Amplifier
Battery
Power and Battery Management
Logic
Power
ADC/DAC
Clocks
Other
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
Infusion pump system block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
50
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Infusion Pump
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
Applications
Processor
Ultra-Low-Power
16-Bit MCU
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
High performance at handheld power levels
32 to 60KB Flash, 1KB/2KB RAM, 8-channel 12-bit ADC,
comparator, 2x SPI + UART, SVS, 160-segment LCD
controller
Ultra-low-power, integrated analog peripherals,
hardware communication channels
MSP430FG461x
Ultra-Low-Power
16-Bit MCU
92 to 120KB Flash, 4KB/8KB RAM, 12-channel 12-bit
ADC, dual 12-bit DAC, comparator, 3 op amps,
3-channel DMA, SPI + UART, USCI, SVS, 160-segment
LCD controller
Ultra-low-power signal-chain-on-chip (SCoC),
configurable op amps, multiple hardware
communication channels
MSP430FG43x
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator,
video accelerators
Laptop-like performance at handheld power levels
OMAP3503,
OMAP3515,
OMAP3525
OMAP-L137
Low-Power
Application
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™ floatingpoint DSP core, rich peripheral set including 10/100
Ethernet MAC, LCD controller, USB 2.0 HS OTG, USB 1.1
full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low
OMAP-L138
system cost and maximum flexibility for connectivity,
GUI, and high-level OS options. Extends product
battery life by providing greater than 60% power
reduction over existing solutions in the market.
Stellaris®
LM3S3xxx
Microcontroller
ARM® Cortex-M3, up to 256KB flash, up to 64kB RAM,
USB host/device
USB, 10-bit ADC, temperature sensor
TMS320F28022
Low-End 32-Bit
MCU with Analog
Integration
Small packages, integration, real-time control
performance
System cost optimization
F2802x Piccolo™
series
TMS320F28032
Mid-End 32-Bit
MCU with Analog
Integration
Integration, up to 128KB Flash, control-law accelerator,
real-time control performance
System cost optimization, performance at lower
power
F2803x Piccolo series
ADS1246
Delta-Sigma ADC
24-bit, 2kHz with PGA, 50/60Hz noise rejection
Integration with performance and low power
ADS1247, ADS1248,
ADS1258
Delta-Sigma ADC
16-channel, 24-bit, 125kSPS, 23.7kSPS/channel
Fastest multi-channel, delta-sigma ADC, measures
all 16 inputs in <675μs
ADS1256, ADS1255,
ADS8344, ADS1158
ADS7952
SAR ADC
12-bit, 1MSPS, 70dB SNR, 11.5mW power
Zero latency, ideal for multi-channel systems
ADS7951, ADS7953
ADS8317
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
Excellent linearity, micropower, high speed
ADS8422
ADS8318
High-Speed SAR
16-bit, 500kSPS, 18mW at 500kSPS power, ±1 LSB INL
Precision, excellent AC/DC performance
ADS8326
SAR ADC, Serial
16-bit, 250kSPS, 2.7V to 5.5V, pseudo-bipolar, diff inputs
Low noise, low power, high speed
ADS8325
ADS8331/32
SAR ADC
16-bit, 500kSPS, 4/8 channels, with serial interface
Mux out feature can be used to reduce system part
count and overall cost
ADS8342
ADS8472
SAR ADC
16-bit, 1MSPS, ±0.4LSB (typ) INL
Zero latency, low power
TLV320DAC3120
Low-Power Audio
DAC
Mono DAC with 2.5W mono Class-D speaker amplifier;
miniDSP for audio processing
Longer battery life, better audio quality, lower cost
TLV320DAC3101
TLV320DAC32
Audio DAC
Low-power stereo DAC, 4 outputs, HP/speaker amplifier,
3D effects
OPA211
Precision Op Amp
—
1.1nV/√Hz noise at 1kHz, ±2.25V to ±18V supply,
80MHz BW
Unity gain stable, RRO, wide supply range
OPA227
OPA365
Op Amp
Zero crossover,
0.0006% THD+N, 100dB CMRR, RRIO,
—
4.5nV/√Hz noise, 50MHz GBW, 200µV input offset
Superior performance, excellent for driving singlesupply ADCs
OPA333, OPA211
OPA376
Precision Op Amp
7.5nV/√Hz noise, 760μA(typ)/ch Iq, 5µV (typ) offset, input
EMI filter, RRO
Low noise, low power, low input bias
OPA340, OPA337
OPA378
Op Amp
0.4µVPP low noise, 125µA (typ) quiescent current,
0.15µV offset voltage, 2.2V to 5V supply
microPower, rail-to-rail I/O, excellent PSRR
OPA330, OPA333,
OPA335
OPA827
Precision JFET
Op Amp
4nV/√Hz noise at 1kHz, ±4V to ±18V supply, 15pA (typ)
input bias current, 22MHz BW
High precision, low noise, low input bias, wide
supply range
OPA177, OPA627,
OPA132, OPA141
INA118
Instrumentation
Amp
110dB CMRR, 5nA (max) bias current, 50µV (max) offset
Wide BW at high gains, ±1.35V to ±18V supply
INA128, INA822
INA333
Instrumentation
Amp
20µV (max) offset, 50nV/°C drift, 200pA input bias
Low power, low drift, tiny package
INA326
TPA2006D1
Analog-Input
Class-D Amp
1.45W mono, filter-free Class D, 1.8V shutdown
AM3517
MSP430F44x
AM3505
Data Converters
Amplifiers
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
51
New products are listed in bold red.
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Infusion Pump
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers (Continued)
TPA2010D1
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Class-AB Audio
Amp
Class-AB Audio
Amp
Low power FDA
2.5W mono, fully differential, filter-free Class D, in WCSP
Loud audio, long battery life, small package size
TPA2031D1
2.7W constant output power, mono, Class D, integrated
boost converter
1.7W stereo, Class D with dynamic range compression
and automatic gain control
1.25W mono, fully differential, Class AB, 1.8V shutdown
Louder audio at low battery levels
TPA2014D1
Loud audio, low cost
TPA6204A1
3.1W mono, fully differential, Class AB
Loud audio
1.14mA (typ) quiescent current, low distortion,
4.6nV/√Hz voltage noise
Low power, high accuracy
THS4522, THS4524
CC1101
Sub-1GHz RF
Transceiver
Wake-on-radio functionality; integrated packet handling
with 64B data FIFOs; high RF flexibility: FSK, MSK, OOK,
1.2-500kbps; extremely fast PLL turn-on/hop time
CC2500
CC1150
Sub-1GHz
Transmitter
Programmable data rate from 1.2 to 500 kBaud; fast
startup time (0.3µs); low current consumption
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended temperature
range; AES-128 security module
Ideal for low-power systems; any low-end MCU
can be used; backwards compatible with existing
systems; suitable for fast frequency hopping
systems
Fast development time and low system cost;
flexible optimization of range vs. power; small
solution size
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal
for industrial applications; no external processor
needed for secure communication
TPA2013D1
TPA2016D2
TPA6205A1
TPA6211A1
THS4521
RF ICs
RF Transceivers
CC2520
RF Systems-on-Chip
CC2560
CC1110/11
CC2431
CC2530/31
CC2540
WL1271
WL1273
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital radio
processor technology.
MCU, USB 2.0, Flash and RAM in one package; four
flexible power modes for reduced power consumption;
includes CC1101 transceiver frequency synthesizer;
built-in AES-128 encryption coprocessor
System-on-Chip
Solution for ZigBee
location engine
Second Gen
System-on-Chip
Solution for 2.4GHz
IEEE 802.15.4/
RF4CE/ZigBee
2.4GHz
Bluetooth® Low
Energy compliant
RF System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
CC2431 has 32/64/128 KB hardware AES encryption
engine, excellent selectivity, blocking performance and
hardware location
Excellent RX sensitivity, low power, easy-to-use
development tools
2.4/5GHz
802.11a/b/g/n
and Bluetooth®
2.1 Chipset
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
Ideal for battery operated systems; suitable for
proprietary and ZigBee systems; adds location
awareness and accuracy of 3 to 5 meters
RF design SOC for quick time to market; provides
a robust and complete ZigBee USB dongle or
firmware-upgradable network node
Excellent link budget enabling long range applications
without external frontend, receiver sensitivity, selectivity
and blocking performance
A fast-to-market Bluetooth® low energy compliant
solution
Single-chip 802.11b/g/n WLAN and Bluetooth® solution
using TI’s digital radio processor technology using a
single antenna.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations; supports
ANT+ standard.
Sophisticated low-power technology ideal for
battery operated solutions; coexistence features
enable simultaneous WLAN and Bluetooth®
operations; supports ANT+ standard.
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
CC2510, CC2511
CC2590/91,
CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Second
Generation
Z-Stack™
Network Processor
ZigBee® stack and radio in one chip; implements ZigBee
certified stack; configurable device type and network
settings
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery-operated excellent selectivity
and blocking performance systems; excellent
coexistence with Bluetooth® technology and Wi-Fi.
Multi-chemistry charger
One charge for both Li-Ion and NiCad/NiMH cells
High-discharge-rate battery monitor
Provides true discharge rate for high-current
battery pack
Accurately measures available cell charge
Power Management
bq2000
bq2016
bq20z80A-V110
Battery
Management
Battery
Management
Battery
Management
Patented Impedance Track™ ICs
New products are listed in bold red. Preview products are listed in bold blue.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
52
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Infusion Pump
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
TPS40054/5
DC/DC Controller
Wide VIN controller with adjustable switching frequency
TPS40057
DC/DC Controller
Wide VIN controller with adjustable switching frequency
TPS40077
TPS51020
TPS51116
TPS5124
TPS54110
DC/DC Controller
DC/DC Controller
DC/DC Controller
DC/DC Controller
DC/DC Converter
TPS54310
DC/DC Converter
TPS54350
DC/DC Converter
TPS62040
DC/DC Converter
TPS62220
DC/DC Converter
4.5 to 28V input
Synchrounous dual buck controller
Complete DDR/DDR2 solution
Synchrounous dual buck controller
Externally compensated — adjustable 1.5A integrated
FET switcher
Externally compensated — adjustable 3A integrated FET
switcher
4.5 to 20V input, 3A DC/DC with integrated switch FET,
sync pin, enable
Adjustable 1.2A, 95%-efficient step-down converter,
18µA, MSOP-10
300mA step-down converter in a SOT-23 package
TPS62300/1/2/3/5
Step-Down
Converter
DC/DC Converter
TPS62350
TPS65010
TPS65020
TPS65023
Linear Charge
Management
Linear Charge
Management
Linear Charge
Management
TPS71701
LDO
TPS73101
LDO
TPS74201
LDO
TPS76725
LDO
TPS76733
LDO
TPS76750
LDO
TPS79912
TPS79925
LDO
LDO
Allows flexibility for the input and the switching
frequency
Allows flexibility for the input and the switching
frequency
Supports 5-/12-/24-V intermediate bus voltages
Provides two outputs 180° apart in one package
Provides all output and active termination for DDR
Provides two outputs 180° apart in one package
Provides flexibility and ease of design
TPS40057
TPS40054/5
TPS5124
TPS51020
Provides flexibility and ease of design
Eliminate beat noise/ceramic caps/FPGA/
integration
Maximizes battery life with high efficiency and
low IQ
Small solution size with high-side FET
TPS54550
500mA, 3MHz synchronous step-down converter
Very small inductor and high efficiency
TPS62040
Step-down DC/DC converter with I2C interface for
dynamic voltage scaling
Fully intregrated power and battery management IC
Provides ability to increase conversion efficiency
6-channel power management IC with 3 DC/DCs,
3 LDOs, I2C interface and dynamic voltage scaling
6-channel power management IC with 3 DC/DCs,
3 LDOs, I2C interface and DVS, optimized for
DaVinci™ DSPs
Low-noise, high-bandwidth-PSRR, low-dropout 150mA
linear regulator
Single-output LDO, 150mA, adjustable (1.2V to 5.5V),
cap free, low noise, fast transient response
Single-output LDO, 1.5A, adjustable (0.8V to 3.3V), any
or no cap, programmable soft start
1A single-output LDO with low IQ and fast transient
response
1A LDO with fastest transient response plus ultra-low
supply current
1A LDO with fastest transient response plus ultra-low
supply current
High-performance 200mA in chip-scale package
High-performance 200mA in chip-scale package
Provides complete solution in one package
Provides complete solution in one package
Provides complete DaVinci solution in one package
Filters out wider range of incoming noise with the
high PSRR
Responds to transients faster to keep output
voltage in regulation
Adjust the voltage ramp rate for your processor
requirements
Efficient design allows quick response to dynamic
current requirements
Ultra-low 85µA supply current and 230mV dropout
voltage stretch battery life
Ultra-low 85µA supply current and 230mV dropout
voltage stretch battery life
Very small solution size
Very small solution size
TPS718xx family
TPS725xx family
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
53
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Automated External Defibrillator (AED)
The automated external defibrillator
(AED) is a highly sophisticated microprocessor-based device that monitors,
assesses and automatically treats
patients with life-threatening heart
rhythms. It captures ECG signals from
the therapy electrodes, runs an ECGanalysis algorithm to identify shockable
rhythms, and then advises the operator
about whether defibrillation is necessary. A basic defibrillator contains a
high-voltage power supply, storage
capacitor, optional inductor, and
patient electrodes (see block diagram).
It develops an electrical charge in the
capacitor to a certain voltage, creating
the potential for current flow. The
higher the voltage, the more current
can poten­tially flow. The AED outputs
audio instructions and visual prompts
to guide the operator through the
defib­ril­lation procedure. In a typical
defibrillation sequence, the AED provides voice prompts to instruct the
user to attach the patient electrodes
and starts acquiring ECG data. If the
AED analyzes the patient’s ECG and
detects a shockable rhythm, the capac­
itor is charged according to energy
stored in the capacitor, Wc = 1/2CV2c ;
and capacitor voltage, Vc(t) = Vc(0)e–t/RC,
where R = R(lead) << R(chest).
Then, following the instructions, the
operator presses the shock button to
deliver the high-voltage pulse; so
current begins flowing through the body
to depolarize most of the heart cells,
which often re-establishes coordinated
contractions and normal rhythm. The
amount of flowing current is determined
by the capacitor and body impedance.
The accompanying graph shows the
level of current and the length of time
the current flows through the body.
Many jurisdictions and medical directors
also require that the AED record the
audio from the scene of a cardiac
arrest for post-event analysis. All AEDs
include a means to store and retrieve
patient ECG patterns.
The front-end signals of the AED come
from the ECG electrodes placed on the
patient, which requires an instrumentation amplifier to amplify its very small
amplitude (<10mV). The instrumentation amplifiers INA118/INA128/INA333
are designed to have:
• Capability to sense low-amplitude
signals from 0.1mV to 10mV,
• Very high input impedance (>5MΩ),
• Very low input leakage current (<1µA),
• Flat frequency response of 0.1Hz to
100Hz and
• High common-mode rejection ratio
(CMRR) (>100dB).
The other front-end signal of the AED
is the microphone input for recording
the audio from the scene of a cardiac
arrest. Both ECG and microphone
input are digitized and processed by
a DSP. Most AED designs use a 16-bit
processor and therefore work well with
16-bit ADCs to digitize ECG and voice
input. The amplified ECG signal has
Isolated Power
Patient Monitoring Signal Chain
Patient
Monitoring
Sensor Pads
FLASH
ADC
DE-FIB
Plates
Audio
Amp
CODEC
Memory
Card
Power
Instrumentation
Buffer
Amplifier
Amplifier
High Voltage
Storage and
Discharge
Circuit
DRAM
Removable
Memory
High Voltage
Digital
Power
Controller
Speaker
Touch
Screen
Operations and Patient
Diagnostics
Backlight
System Monitoring and
Management (Wake DSP)
Display
Operator/Patient Feedback and Instructions
Low Noise
Sensor Power
Processor
Power
Battery
Charger
Keypad
Low Power Wireless
Lithium
Battery
Protection
System
Power
Fuel
Gauge
Power Supply
Battery Pack
LEGEND
Patient Monitoring and Data Upload
AC/DC Supply
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Plug
AC
Adapter
AC Line
Product Availability and Design Disclaimer – The system block diagram depicted above and the devices recommended are designed in this manner as a reference. Please contact your local TI sales office or
distributor for system design specifics and product availability.
AED system block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
54
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Automated External Defibrillator (AED)
40
200J Monophasic
30
200J Biphasic
130J Biphasic
20
Current (A)
a bandwidth of 0.1Hz to 100Hz and
requires a minimum SNR of 50dB.
The audio recording/playback signal
typically has a bandwidth of 8kHz and
requires a minimum SNR of 65dB. The
microphone input also needs to be
amplified with a maximum programmable gain of 40dB. The AED can have
synthesized audio instruction with
volume control output to either the
headphone speaker or the 8Ω speaker.
System designers will find that the
TLV320AIC20K makes the AED frontend digitization very easy and simple
because it integrates two ADCs, two
DACs, a microphone amplifier, a headphone driver and an 8Ω driver with
volume control; and it can be seamlessly interfaced to a DSP.
10
0
–10
–20
0
5
10
Time (ms)
20
15
Typical AED drive current. AEDs can deliver either monophasic or biphasic defibrillation waveforms to the heart. Monophasic delivers a current that travels in one
direction throughout the shock. Newer biphasic technology allows the current to
be reversed partway through the shock thus potentially lessening the risk of burns
and myocardial damage.
Single-Supply, microPower, RRO, CMOS Instrumentation Amplifier
INA321
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/INA321
Key Features
• Low quiescent current: 40µA/ch
• High gain accuracy: 2ppm/°C,
0.02%, G = 5
• Low offset voltage: ±200µV
• High CMRR: 94dB
• Low bias current: 10pA
• Bandwidth: 500kHz, G = 5V/V
• Gain set with external resistors
• Packaging: MSOP-8 (single);
TSSOP-14 (dual)
The INA321 is a rail-to-rail output, CMOS instrumentation amp that provides
amplification of differential signals with microPower current consumption of 40µA.
It features <1µA current consumption in standby mode and returns to normal
operation in microseconds making it a good choice for low-power battery or
multiplexing applications. Configured internally for 5V/V gain, the INA321 offers
exceptional flexibility with user-programmable external gain resistors. It reduces
common-mode error over frequency and with CMRR remaining high up to 3kHz,
line noise and line harmonics are rejected.
R1
160kΩ
40kΩ
R2
RG
40kΩ
160kΩ
REF
Applications
• Physiological amplifier: ECG, EEG,
EMG
• Test equipment
• Differential line receivers with gain
• Industrial sensor amplifier: bridge,
RTD, thermistor, position
A1
VIN–
VOUT
A3
A2
VIN+
Gain = 5 + 5(R2/R1)
VOUT = (VIN+ – VIN-) • Gain
Shutdown
V+
V–
INA321 functional block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
55
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Automated External Defibrillator (AED)
Component Recommendations
Component
Description
Key Features
Benefits
Other TI Solutions
Amplifiers
INA118
INA128
INA321
*Page 55
INA333
OPA333
OPA369
TPA2005D1
TPA2010D1
TPA2013D1
TPA3007D1
TPA6205A1
TPA6211A1
THS452x
Instrumentation
Amp
Instrumentation
Amp
CMOS
Instrumentation Amp
Instrumentation
Amp
Precision Op Amp
Zero-Crossover Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Analog-Input
Class-D Amp
Class-AB
Audio Amp
Class-AB
Audio Amp
Low power FDA
110dB CMRR, 5nA (max) bias current, 50µV (max)
offset
50µV offset voltage, drift (0.5µV/°C) and high
common-mode rejection (120dB at G ≥ 100)
0.02% accuracy, 2ppm/°C drift for gain=5; 10pA
input bias current
25μV (max) offset, 50nV/°C drift, 50μA (typ) Iq
1.8V min supply, 0.017mA/ch (max), 10μV offset
(max), 0.05 μV/°C drift (max)
1.8V, 700nA, RRIO, 114dB CMMR, 0.4µV/°C drift
1.4W mono, fully differential, filter-free Class D
Wide BW at high gains, ±1.35V to ±18V supply
INA128
Wide BW at high gains
INA129
High gain accuracy
INA2321 (dual)
Best offset/noise combination, supply down to 1.8V,
low power
Zero drift, high precision, low power, EMI input
INA321, INA326
Low power, unmatched DC precision
Loud audio, long battery life
OPA335, OPA378,
OPA330
OPA379, OPA2369 (dual)
TPA2006D1
2.5W mono, fully differential, filter-free Class D, in
WCSP
2.7W constant output power, mono, Class D,
integrated boost converter
Mono, medium power, filter-free Class D
Loud audio, long battery life, small package size
TPA2031D1
Louder audio at low battery levels
TPA2014D1
1.25W mono, fully differential, Class AB, 1.8V
shutdown
3.1W mono, fully differential, Class AB
Loud audio, low cost
TPA6204A1
1.14mA (typ) quiescent current,+2.5V to 5.5V supply
Low power, single and dula supply, low distortion
THS4522, THS4524
16-bit, 860SPS, 4 SE, 2 diff input, PGA, MUX,
comparator, VREF
24-bit, 8 PGA, 8 ADC, plus RLD and RESP
Smallest 16-bit ADC, 2.0 x 1.5 x .04 mm leadless
WFN pkg; reduces system size and componenent count
Complete front end, reduction in power and size,
increase reliability
ADS1113/4,
ADS1013/14/15
ADS1294, ADS1296,
ADS1198, ADS1251/58
ADS7924, ADS8201
ADS8326
Loud audio
Data Converters
ADS1115
Delta-Sigma ADC
ADS1298
ECG/EEG AFE
ADS7866
ADS8317
SAR ADC, Serial
SAR ADC
ADS8326
Low-Power ADC
ADS8331/32
SAR ADC
MSC1210
TLV320AIC12K
Data Acq. System
Audio Codec
TLV320AIC20K
Audio Codec
TLV320AIC3104
Audio Codec
TLV320DAC3120
Low-Power Audio
DAC
Audio Converter
TLV320DAC32
TSC2003
TSC2046
Touch-Screen
Controller
Touch-Screen
Controller
1.2V, 12-bit, 200kSPS (max), 85dB SFDR
16-bit, 250kSPS, 2.7V to 5.5V supply, ±1.5 LSB
(max) INL, differential input
16-bit, 250kSPS, 2.7V to 5.5V supply,
±1.5 LSB (max) INL
16-bit, 500kSPS, 4/8 channels, with serial interface
Enhanced 8051 core w/Flash memory and 24-bit ADC
Low-power, mono, voice-band codec with 8Ω
speaker amp
Low-power, stereo, voice-band codec with 8Ω
speaker amp
Low-power stereo codec, 6 inputs, 6 outputs,
headphone amp, enhanced digital effects
Mono DAC with 2.5W mono Class-D speaker
amplifier; miniDSP for audio processing
Low-power stereo DAC, 4 outputs, HP/speaker
amplifier, 3D effects
I2C interface for standard, fast, high-speed modes
Low voltage I/O, touch-pressure measurement, 2.2V
to 5.2V operation
Low power, small package, and wide supply range
Small package, wide supply range
Mux out feature can be used to reduce system part
count and overall cost
ADS8342
Fully compatible with TMS320C54x™ DSP power
supplies
TLV320AIC24K
Longer battery life, better audio quality, lower cost
TLV320DAC3101
Direct battery measurement
ADS7845, TSC2000,
TSC2007
QSPI™ and SP™ 3-wire interface
References
REF30xx
REF31xx
REF32xx
REF33xx
REF50xx
Low-Power,
Low-Drift Series
Reference
Series Voltage
Ultra-Low-Drift
Series Reference
Very-Low-Power
Series Reference
High-Precision,
Very-Low-Drift
Series Reference
50µA, 0.2% initial accuracy, 50ppm/°C max drift,
±25mA output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V,
4.096V
0.2% (max) initial accuracy, 15ppm/°C (max) drift, 100µA
1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
100µA, 0.2% initial accuracy, 7ppm/°C max drift,
±10mA output, 1.25V, 2.048V, 2.5V, 3.0V, 3.3V, 4.096V
5µA, 0.15% initial accuracy, 30ppm/°C max drift,
±5mA output, 1.25V, 1.8V, 2.048V, 2.5V, 3.0V, 3.3V
0.05% initial accuracy, 3ppm/°C max drift, ±10mA
output, 2.048V, 2.5V, 3.0V, 4.096V, 4.5V, 5.0V
*For additional product information see designated page number.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
REF31xx, REF33xx,
REF29xx
Low power consumption for portable applications
REF3120, REF3125,
REF3133
Improves system accuracy
Preserves battery life, fits into physically constrained
systems
Improves system accuracy
REF30xx, REF31xx,
REF29xx
REF02
New products are listed in bold red. Preview products are listed in bold blue.
56
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Automated External Defibrillator (AED)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Processors
Applications
Processor
Ultra-Low-Power
16-Bit MCU
ARM® Cortex-A8, graphics accelerators, Ethernet, CAN
High performance at handheld power levels
1KB/2KB Flash, 128B RAM, SPI+I2C
8 ch. 12-bit ADC or 4 ch. 16-bit SD ADC, 4 x 4mm
package
MSP430F22x4
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 512B/1KB RAM, SPI + I2C +
UART/LIN + IrDA
12 ch. 10-bit ADC, 2 op amps
MSP430F23x0
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 1KB/2KB RAM, SPI + I2C +
UART/LIN + IrDA
Analog comparator, HW multiplier
MSP430F41x
Ultra-Low-Power
16-Bit MCU
4 to 32KB Flash, 256B to 1KB RAM, SVS,
96 segment LCD
Analog comparator
MSP430F42x
Ultra-Low-Power
16-Bit MCU
8 to 32KB Flash, 256B to 1KB RAM, SPI + UART, SVS,
128 segment LCD
3 x 16-bit SD ADC
MSP430F42x0
Ultra-Low-Power
16-Bit MCU
16 to 32KB Flash, 256B RAM, 56 segment LCD
5 ch. 16-bit SD ADC, 12-bit DAC
MSP430F43x
Ultra-Low-Power
16-Bit MCU
16 to 32KB Flash, 512B/1KB RAM, SPI + UART, SVS,
160 segment LCD
8 ch. 12-bit ADC, analog comparator
MSP430F44x
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 1KB/2KB RAM, 2x SPI + UART,
SVS, 160 segment LCD
8 ch. 12-bit ADC, HW multiplier
MSP430F47xx
Ultra-Low-Power
16-Bit MCU
60KB Flash, 256B RAM, (4) USCI, 160 segment LCD
(4) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
MSP430F241x
Ultra-Low-Power
16-Bit MCU
120KB Flash, 8KB RAM, (4) USCI, SVS, temp. sensor
8 ch. 12-bit ADC, analog comparator, HW multiplier
MSP430F261x
Ultra-Low-Power
16-Bit MCU
120KB Flash, 8KB RAM, (4) USCI, SVS, DMA, temp.
sensor
Analog comparator, 2 ch. 12-bit DAC, 8 ch. 12-bit
ADC, HW multiplier
MSP430F471xx
Ultra-Low-Power
16-Bit MCU
120KB Flash, 8KB RAM, (4) USCI, DMA, 160
segment LCD
(7) SD16 ADC, HW multiplier, temp. sensor, analog
comparator
MSP430F54xxA
Ultra-Low-Power
16-Bit MCU
128 to 256KB Flash, 16KB RAM, (4) USCI, PMM,
DMA, temp. sensor
16 ch. 12-bit ADC, analog comparator, RTC, internal
voltage regulator for power optimization
MSP430FG42x0
Ultra-Low-Power
16-Bit MCU
16 to 32KB Flash, 256B RAM, 56 segment LCD
5 ch. 16-bit SD ADC, 12-bit DAC, 2 integrated
op amps
MSP430FG43x
Ultra-Low-Power
16-Bit MCU
32 to 60KB Flash, 1KB/2KB RAM, SPI + UART, SVS,
128 segment LCD
12 ch. 12-bit ADC, 2 ch. 12-bit DAC, DMA, 3 op amps
MSP430FG461x
Ultra-Low-Power
16-Bit MCU
92 to 120KB Flash, 4KB/8KB RAM, SPI + I2C + UART/
LIN + IrDA, 160 LCD
12 ch.12-bit ADC, 2 ch.12-bit DAC, A-comp,
3 op amps, HW multiplier
OMAP3530
Applications
Processor
ARM® Cortex-A8, C64x+™, graphics accelerator,
video accelerators
Laptop-like performance at handheld power levels
OMAP3503, OMAP3515,
OMAP3525
OMAP-L137
Low-Power
Applications
Processor
300MHz ARM9™ w/MMU + 300MHz C674x™
floating-point DSP core, rich peripheral set including
10/100 Ethernet MAC, LCD controller, USB 2.0 HS
OTG, USB 1.1 full speed, SPI and MMC/SD
Highly integrated, dual-core solution drives low system cost
and maximum flexibility for connectivity, GUI and high-level OS
options. Extends product battery life by providing greater than
60% power reduction over existing solutions in the market.
OMAP-L138
Stellaris®
LM3S3xxx
Microcontroller
ARM® Cortex-M3, up to 256KB flash, up to 64kB
RAM, USB host/device
USB, 10-bit ADC, temperature sensor
TMS320C5000™
DSP
Power efficient, high performance
Fixed-point DSP with industry’s best combination of
standby and dynamic power consumption
TMS320VC5506
DSP
200MHz, dual MAC, very low standby power of
0.12mW
Supported by eXpressDSP™ and many other
software packages and tools
TMS320VC5509A,
TMS320VC5502
bq77PL900
AM3517
MSP430F20xx
AM3505
Power Management
bq20z90-V110
Battery Fuel
Gauge
Instant accuracy better than 1% error over lifetime
of the battery
Automatically adjusts for battery aging, battery self
discharge and temperature inefficiencies
bq24100
Battery Charge
Management
Battery Charge
Management
Battery Safety
Switch mode, 1100kHz switching frequency, >2A
charge current
Multi-chemistry and multi-cell sync switch-mode
charger
Battery pack full-protection analog front end
d/dt, min current primary charge termination method
Isolated DC/DC
Converter
USB Power Switch
2W, unregulated, up to 89% efficiency, 106W/in3
power density
USB-compliant power source, short-circuit
protection
bq24721C
bq29330
DCP020515D
TPS2041B
Provides individual cell voltages and battery voltage
to battery management host
EN55022 Class B EMC performance, UL1950
component
Single-chip power source solution for USB and
memory cards
DCP02 series
TPS2550, TPS2061
New products are listed in bold red.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
High efficiency, pack and system protection functions
57
Texas Instruments 2010
Diagnostic, Patient Monitoring and Therapy
➔ Automated External Defibrillator (AED)
Component Recommendations (Continued)
Component
Description
Key Features
Benefits
Other TI Solutions
Power Management (Continued)
TPS22902
TPS2550
Load Switch with
Controller Turn-On
Current Limited
Load Switch
USB Power Switch
Low on resistance, controlled turn-on, ultra small
64mm2 package, quick output discharge
Configurable current limit, ultra-small package, 1µA
quiescent current at 1.8V
Precision OC USB power switch with UL approval
TPS2828
MOSFET Driver
TPS3836
Voltage Supervisor
TPS61042
White LED Driver
TPS717xx
TPS718xx-yy
Low-Noise SingleChannel LDO
Dual-Channel LDO
2A output, 14ns rise and fall time, 24ns prop delay,
inverting
220nA supervisor with 10ms/200ms selectable
delay time
30V, 500mA switch boost converter, 1MHz switching
frequency
Very high rejection of power-source noise
TPS780xx
LDO with DVS
Dynamic voltage scaling (DVS) with low IQ 500nA
UCC38C4x
PWM Controller
UCD7100
Digital Control
Driver
14.9/9V on/off UVLO thresholds, 1MHz frequency,
50% duty cycle
Adjustable current limit, 3.3V, 10mA internal
regulator
TPS22946
Very high rejection of power-source noise
Ultra-small, fully integrated solution
Ultra-small, low quiescent current current limited switch
Provides precise adjustable current limit for multiple
applications
Drives FETs for high-voltage transformer
Circuit initialization and timing supervision
Higher switching frequency requires smaller size
inductor and capacitor
Low-noise power rails for sensitive analog
components
Low-noise power rails for sensitive analog
components
DVS voltage designed to operate with MSP430 to
increase power savings
TPS22901, TPS22922,
TPS22924C, TPS22960
TPS22949, TPS22945
TPS2551
TPS2829 non-inverting
version
TPS3809
TPS61140
TPS793xx, TPS795xx,
TPS799xx
TPS719xx-yy
TPS78101
UCC3804, UCC3809
Applications requiring fast local peak current limit
protection
RF ICs
RF Transceivers
CC1101
Sub-1GHz RF
Transceiver
CC2520
2.4GHz ZigBee®/
IEEE 802.15.4 RF
Transceiver
Wake-on-radio functionality; integrated packet
handling with 64B data FIFOs; high RF flexibility:
FSK, MSK, OOK, 1.2-500kbps; extremely fast PLL
turn-on/hop time
Best-in-class coexistence and selectivity properties;
excellent link budget (103dBm); extended
temperature range; AES-128 security module
Ideal for low-power systems; any low-end MCU
can be used; backwards compatible with existing
systems; suitable for fast frequency-hopping systems
CC2500
Reliable RF link with interference present; 400m
line-of-sight range with the development kit; ideal for
industrial applications; no external processor needed
for secure communication
CC2530
RF Systems-on-Chip
CC2560
CC1110/11
2.4GHz Bluetooth®
2.1 chipset
Sub-1GHz
System-on-Chip
Single-chip Bluetooth® solution using TI’s digital
radio processor technology.
MCU, USB 2.0, Flash and RAM in one package;
four flexible power modes for reduced power
consumption; includes CC1101 transceiver
frequency synthesizer; built-in AES-128 encryption
coprocessor
CC2431 has 32/64/128 KB hardware AES encryption
engine, excellent selectivity, blocking performance
and hardware location
Sophisticated low-power technology ideal for battery
operated solutions
Complete low-cost solution on single chip; ideal for
low-power battery-operated systems; robust and
secure link with good noise immunity; no external
processor needed for secure communication; can
connect directly to a PC
Ideal for battery operated systems;suitable for
proprietary and ZigBee systems; adds location
awareness and accuracy of 3 to 5 meters
CC2431
System-on-Chip
Solution for Zigbee
location engine
CC2530/31
Second Generation
System-on-Chip
Solution for 2.4GHz
IEEE 802.15.4/
RF4CE/ZigBee
2.4GHz Bluetooth®
Low Energy
compliant RF
System-on-Chip
2.4GHz 802.11b/g/n
and Bluetooth® 2.1
Chipset
Excellent RX sensitivity, low power, easy-to-use
development tools
RF design SOC for quick time to market; provides a
robust and complete ZigBee USB dongle or firmwareupgradable network node
Excellent link budget enabling long range
applications without external frontend, receiver
sensitivity, selectivity and blocking performance
A fast-to-market Bluetooth® low energy compliant
solution
Single-chip 802.11b/g/n WLAN and Bluetooth®
solution using TI’s digital radio processor technology
using a single antenna.
2.4/5GHz
802.11a/b/g/n and
Bluetooth® 2.1
Chipset
Single-chip 802.11a/b/g/n WLAN and Bluetooth®
solution using TI's digital radio processor technology
using a single antenna.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations; supports
ANT+ standard.
Sophisticated low-power technology ideal for battery
operated solutions; coexistence features enable
simultaneous WLAN and Bluetooth® operations;
supports ANT+ standard.
CC2540
WL1271
WL1273
CC2510, CC2511
CC2590/91, CC2530ZNP
WL1273
WL1271
RF Network Processor
CC2530ZNP
Second Generation
Z-Stack™
Network Processor
ZigBee® stack and radio in one chip; implements
ZigBee certified stack; configurable device type and
network settings
New products are listed in bold red. Preview products are listed in bold blue.
To view more system block diagram compatible products, visit www.ti.com/medical
Diagnostic, Patient Monitoring and Therapy Applications Guide
Add CC2530ZNP and your system is ZigBee enabled;
ideal for battery-operated excellent selectivity and
blocking performance systems; excellent coexistence
with Bluetooth® technology and Wi-Fi.
58
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Overview
Connectivity plays an important role
in clinical, patient monitoring, and
consumer medical devices. While
wired (USB) connections continue to
be used, emphasis is being placed
on wireless capabilities that enable
connected or networked devices.
Portability requirements call for these
devices to be small in size, consume
minimal power and include the ability
to efficiently and accurately feed data
to remote sources.
TI has long-time experience providing a
wide range of innovative wireless tech­
nologies. Some of these technologies
include ZigBee®, radio frequency identification (RFID), low-power wireless
(ISM), Bluetooth® technology and WLAN.
USB for Medical Applications
Connectivity for portable medical
applications has become critical as
consumers and caregivers are requiring data to move from medical devices
to data hubs such as computers and
mobile phones. TI is a promoting
member of the
Continua Health
Alliance and now
offers the first
Continua-certified
USB platform for Agent Devices.
See page 60 for more information.
For more information on the
Continua Health Alliance, visit
http://www.continuaalliance.org
ZigBee® and Bluetooth®
Low Energy Solutions
for Medical Applications
More and more medical devices,
especially in patient monitoring and
home healthcare, can benefit from
wireless technologies such as ZigBee
and Bluetooth Low Energy.
The ZigBee standard enables
companies to have a simple, reliable,
low-cost and low-power standardbased wireless platform for their
medical application development.
As an example, with the use of ZigBee
wireless sensors, patients can move
around in the hospital, or even in
their homes, and the sensors will still
monitor and send critical health data
to the hospital or doctor.
Bluetooth Low-Energy
solutions are designed for
low-cost, low-power and
short range connectivity.
The technology enables
direct communication to cellular
phones, laptops and other Bluetooth
enabled devices such as sports and
fitness watches, GPS / handhelds,
and other personal monitoring devices.
For more information, visit:
www.ti.com/zigbee
www.ti.com/bluetoothlowenergy
Radio Frequency Identification (RFID)
TI’s high-frequency RFID product family
consists of 13.56MHz high-frequency
(HF) transponders and low-power RFID
readers that are compliant with ISO/IEC
15693 and ISO/IEC 18000-3 global
open standards.
Typical RFID medical applications
include blood bag and medical supply
tracking, patient/staff authentication,
pharmaceutical authentication, medical
imaging, product authentication and
remote digital healthcare management
applications.
TI’s Tag-it™ HF-1 family of transponder
inlays consists of 13.56MHz HF transponders that are compliant with ISO/
IEC 15693 and ISO/IEC 18000-3 global
open standards. These products are
available in six different antenna shapes
with frequency offset for integration
into paper, PVC or other substrates
manufactured with TI’s patented lasertuning process to provide consistent
read performance.
Texas Instruments supports the ZigBee
Personal Health (PH) profile as well as
the Continua Alliance/ EN11073 profile.
Connectivity
ZigBee®/
IEEE 802.15.4
Bio Sensors
Embedded
Processor-Based
Portable Medical
Device
(Includes sensor
interface, processor,
user I/O, and power
management)
Bluetooth®
Wireless Data
Transmission
Sub-1GHz ISM RF
USB Controller
Wired Data
Transmission
TI has considerable experience designing connectivity solutions for
interoperability and coexistence.
Diagnostic, Patient Monitoring and Therapy Applications Guide
59
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Overview (Continued)
Low-Power Wireless (ISM)
TI offers a wide selection of costeffective, low-power RF solutions for
both proprietary and standard-based
wireless applications. The portfolio
includes RF transceivers, RF transmitters and Systems-on-Chip for shortrange applications in the sub-1GHz
and 2.4GHz frequency bands.
To choose the right radio for specific
applications, designers need to determine at what frequency band to operate.
TI’s radios operate in either the global
2.4GHz or the sub-1GHz Industrial
Scientific Medical (ISM) bands. The
2.4GHz is available for license-free
operation in most countries around the
world and enables the same solution to
be sold in several markets without
software/hardware alterations.
The ISM bands below sub-1GHz have
limitations that vary from region to
region, but their strength is a better
range than 2.4GHz with the same output power and current consumption.
In addition, there is less interference
present in the band. Since different
sub-1GHz bands are used in different
markets, custom solutions become a
necessity.
The trade-off between the need for
interoperability and the cost of software design and development will, to
a large extent, determine the choice of
software platform. TI’s software portfolio ranges from proprietary solutions
with a high degree of design freedom
and low complexity to fully interoperable ZigBee® solutions.
➔ Medical USB Platform
TI offers a Continua-certified USB
hardware-software platform that
implements the Personal Healthcare
Device Class (PHDC) along with IEEE
11073. As personal healthcare devices
become more ubiquitous, companies
are developing products with connectivity that allow data to be exchanged
easily. PHDC (Personal Healthcare
Device Class), which is part of the
USB standard, is designed for portable
medical and wellness devices to be
able to send measurements to USB
hosts such as personal computers,
cell phones, etc. The Continua Health
Alliance has released guidelines for
interoperability between various types
of devices implementing the USB
standard. Texas Instruments offers a
hardware-software platform that has
been certified by the Continua Health
Alliance after having passed a rigorous
testing procedure. Customers can use
the software stacks of this platform to
reduce development time for devices
that will comply with the medical industry standards such as the Continua
Health Alliance. These stacks are available for use on TI’s industry-leading,
ultra-low-power MSP430™ MCUs.
For more information on the
Continua Health Alliance, visit
http://www.continuaalliance.org.
For more information on the
medical USB platform, visit
http://www.ti.com/usbplatform.
Medical Application
Device Specializations
IEEE 11073-104xx
Data Exchange Protocol
IEEE 11073-20601
Diagnostic, Patient Monitoring and Therapy Applications Guide
USB API
PHDC
CDC
HID
MSD
Physical Layer
60
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Wired Solutions
USB-to-Serial Bridge
TUSB3410
Get samples, datasheets, application reports and evaluation modules at: www.ti.com/sc/device/TUSB3410
Key Features
• USB full-speed (12Mbps) compliant
• Integrated 8052 microcontroller with
16K bytes of RAM that can be
loaded from the host or external
memory via an I2C bus
• Integrated, enhanced UART features
include:
• Programmable software/hardware
flow control
• Automatic RS-485 bus transceiver
control, with and without echo
• Software-selectable baud rate
from 50 to 921.6K baud
• Built-in, 2-channel DMA controller
for USB/UART bulk I/O
• TUSB3410UARTPDK product development kit can jump-start USB-toserial development
Applications
• Handheld meters
• Health metrics/monitors
• Legacy-free PC COM port
replacement
TUSB3410 and TUSBWINVCP software provides an easy way to move serialbased legacy devices to a fast, flexible USB interface by bridging a USB port and
an enhanced UART serial port. The TUSB3410 contains all of the logic needed to
communicate with the host computer using the USB bus. The TUSBWINVCP software package enables the TUSB3410 to act as a virtual COM port and appear as
legacy COM ports on the back of older model computers. This enables the use of
existing devices and application software without making any changes.
3.6V
EEPROM
Parameter
Storage
V-REG
5V
Host PC
USB
*Several new MSP430™ families
such as F552x have integrated USB
capabilities where an external USB
controller is not required
SDA
SCL
TUSB3410
USB Controller
12MHz
MSP430*
7 3728MHz
TUSB3410/MSP430™ implementation block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
61
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Wireless Interface, RFID and Tag-it™
Radio Frequency Identification
(RFID)
TI’s high-frequency RFID product
family consists of 13.56MHz highfrequency (HF) transponders and lowpower RFID readers that are compliant
with ISO/IEC 15693 and ISO/IEC
18000-3 global open standards.
Typical RFID implementations include
asset tracking, access control, blood
bag tracking, medical supply tracking,
patient/staff authentication, pharma­
ceutical authentication, medical imaging,
product authentication, remote digital
healthcare management applications and many non-medical related
applications.
open standards. These products are
available in six different antenna shapes
with frequency offset for integration
into paper, PVC or other substrates
manufactured with TI’s patented lasertuning process to provide consistent
read performance. Prior to delivery, the
transponders undergo complete functional and para­metric testing to provide
the high quality customers have come
to expect.
• Data retention time (at +55°C):
>10 years
Tag-it HF-I Family
• 256-bit user memory, 8 x 32-bit
• Password-protected write command
• Command to disable IC functionality
• FastSID
Key Features
• User and factory lock per block
• Application Family Identifier (AFI)
Standard
• 256-bit user memory, 8 x 32-bit
• FastSID
Pro
Product Specifications
• Supported standards: ISO/IEC
15693-2, -3; ISO/IEC 18000-3
• Recommended operating frequency:
13.56MHz
• Factory programmed read-only
numbers: 64-bit
• Typical programming cycles (at
+25°C): 100,000
Tag-it HF-I Transponder Inlays
TI’s Tag-it HF-I family of transponder
inlays consists of 13.56MHz HF transponders that are compliant with ISO/
IEC 15693 and ISO/IEC 18000-3 global
Plus
• 2Kbit user memory, 64 x 32 6-bit
• Data Storage Format Identifier
(DSFID)
• Combined inventory read block
Tag-it™ HF-I Plus Inlay Shapes
Part Number
Available Memory
Antenna Size (mm)
Foil Pitch (mm)
Frequency Offset for
Lamination Material
Delivery
RI-I11-112A-03
RI-I11-112B-03
RI-I02-112A-03
RI-I02-112B-03
RI-I03-112A-03
RI-I15-112B-03
RI-I16-112A-03
RI-I17-112A-03
2K bits organized in 64 x 32-bit blocks
45 x 45
45 x 45
45 x 76
45 x 76
22.5 x 38
34 x 65
θ 24.2
θ 32.5
50.8 + 0.1/
–0.4 (2 in)
50.8 + 0.1/
–0.4 (2 in)
96 + 0.1/
–0.4 (~3.78 in)
96 + 0.1/
–0.4 (~3.78 in)
58 +0.1/
–0.4 (~1.89 in)
101.6 +0.1/
–0.4 (4 in)
50.8 +0.1/
–0.4 (2 in)
50.8 +0.1/
–0.4 (2 in)
Paper
PVC
Paper
PVC
Paper/PVC
PVC
Paper/PVC
Paper/PVC
Single tape row with 48mm foil width wound on cardboard reel
Tag-it™ HF-I Pro Transponder Inlays
Part Number
Available Memory
Foil Width (mm)
Antenna Size (mm)
Foil Pitch (mm)
Frequency Offset for
Lamination Material
Delivery
RI-I11-114A-S1
RI-I11-114B-S1
RI-I02-114A-S1
RI-I02-114B-S1
RI-I03-114-S1
RI-I16-114-S1
RI-I17-114-S1
256 bits organized in 8 x 32-bit blocks
48mm ±0.5mm
45 x 45
45 x 45
45 x 76
45 x 76
22.5 x 38
θ 24.2
θ 32.5
50.8 +0.1/
–0.4 (2 in)
50.8 +0.1/
–0.4 (2 in)
96 +0.1/
–0.4 (~3.78 in)
96 +0.1/
–0.4 (~3.78 in)
48 +0.1/
–0.4 (~1.89 in)
50.8 +0.1/
–0.4 (2 in)
50.8 +0.1/
–0.4 (2 in)
Paper
PVC
Paper
PVC
Paper/PVC
Paper/PVC
Paper/PVC
RI-I02-114A-01
RI-I02-114B-01
RI-I03-114-01
RI-I16-114-01
RI-I17-114-01
Single row tape wound on cardboard reel
Tag-it™ HF-I Standard Transponder Inlays
Part Number
Available Memory
Foil Width (mm)
Antenna Size (mm)
Foil Pitch (mm)
Frequency Offset for
Lamination Material
Delivery
RI-I11-114A-01
RI-I11-114B-01
256 bits organized in 8 x 32-bit blocks
48mm ±0.5mm
45 x 45
45 x 45
45 x 76
45 x 76
22.5 x 38
θ 24.2
θ 32.5
50.8 +0.1/
–0.4 (2 in)
50.8 +0.1/
–0.4 (2 in)
96 +0.1/
–0.4 (~3.78 in)
96 +0.1/
–0.4 (~3.78 in)
48 +0.1/
–0.4 (~1.89 in)
50.8 +0.1/
–0.4 (2 in)
50.8 +0.1/
–0.4 (2 in)
Paper
PVC
Paper
PVC
Paper/PVC
Paper/PVC
Paper/PVC
Single row tape wound on cardboard reel
Diagnostic, Patient Monitoring and Therapy Applications Guide
62
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Wireless Interface, RFID and Tag-it™
Low-Power, Multi-Standard HF RFID Readers
TRF7960,TRF7961
Get samples and datasheets at: www.ti.com/sc/device/TRF7960 or www.ti.com/sc/device/TRF7961
Key Features
• Supports ISO14443A/B, ISO15693
and Tag-it
• High level of integration reduces total
cost, BOM and board area
• Completely integrated protocol
handling
• Separate, internal high-PSRR
LDOs for analog, digital and PA
sections provide noise isolation for
superior read range and reliability
• Integrated LDO regulator output
for MCU
• Single Xtal system with available
output clock for MCU
• Eleven user-accessible and programmable registers
• Low-power device with wide operating voltage range: 2.7V to 5.5V
Complementing the Tag-it™ HF-I family of transponder inlays is TRF7960, a highly
integrated analog front end and data framing system for any 13.56MHz RFID
reader system. Built-in programming options make TRF7960 useful for a wide
range of applications, both in proximity and vicinity RFID systems. A high level of
integration, excellent performance, miniature size and multiple low-power modes
allow TRF7960 to be used for battery-power-constrained medical applications.
• Programmable output power:
100mW or 200mW
• Parallel 8-bit or serial 4-pin SPI
interface with 12-byte FIFO
• Seven user-selectable,
ultra-low-power modes
• Power down: <1µA
• Standby: 120mA (typical)
• Active: 10mA (RX only)
• Available MSP430™ software
libraries
• Packaging: Ultra-small, 5 x 5mm,
32-pin QFN
Tag
Antenna
13.56 MHz
TRF796x
Timing
System
Supply
Regulators
Protocol Decoders/
Encoders and
Framing
Dual Rx
LC
Network
MSP430
Control
Registers
Tx AFE
Rx Gain
and Filters
SPI
Parallel
Interface
SPI/Parallel
Interface
CPU
CLK_SYS
Digitizer
VDD_X
XIN
DVCC
12 Byte FIFO
Functional block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
63
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Wireless Interface, RFID and Tag-it™
Low-Power, Multi-Standard HF RFID Readers (Continued)
TRF7960,TRF7961
Get samples and datasheets at: www.ti.com/sc/device/TRF7960 or www.ti.com/sc/device/TRF7961
Applications
• Medical
• Patient and staff authentication
• Pharmaceutical authentication
• Product authentication and
calibration
• Remote digital healthcare
management
• Asset tracking
• Access control
• Contactless payments
• Prepaid eMetering
• eGovernment
TRF7960 Evaluation Module
(EVM)
Tag-it™ smart labels bring affordable RFID technology to a wide
range of new applications.
The TRF7960 evaluation tool
allows for quicker and simplified
system design. The TRF7960
multiple-­protocol RFID transceiver
incorporates an analog front end,
protocol handling, framing, error
checking and multiple integrated
voltage regulators with other features that allow the reader to be
customized/configured to the end
application.
TRF7960 EVM features include:
• Fully functional RFID reader with
on-board and (optional) offboard antenna capabilities
• GUI that support the
ISO14443A, ISO14443B,
ISO15693 and Tag-it commands
• Separate LEDs that indicate tag
detection—operates in standalone mode without GUI
Tag-it™ HF-I family transponder inlays are available in a variety of package
options, including square, circular and rectangular (regular and mini).
Diagnostic, Patient Monitoring and Therapy Applications Guide
64
Texas Instruments 2010
Connectivity Solutions for Medical
➔ Low-Power RF Products
Integrated Multi-Channel RF Transceiver
CC1101
Get samples, datasheets, evaluation modules and application reports at: www.ti.com/sc/device/CC1101
Key Features
• Sub-1GHz FSK/GFSK/MSK/ASK/
OOK RF transceiver
• 1.2 to 500Kbaud data rate
• Low power, low system cost
• Sleep current: –200nA
• 90μs PLL lock time: –240μs from
sleep to RX/TX
• On-chip support for sync word
detection, address check, flexible
packet length and automatic CRC
checking
• Separate 64-byte RX and TX data
FIFOs enable burst-mode data
transmission
• Suitable for systems targeting compliance with EN 300, 200 (Europe)
and FCC CFR Part 15 (U.S.)
Need longer RF range? Try the CC2590/
CC1190 2.4GHz and sub 1GHzRF range
extender for low-power RF ICs.
The CC1101 is a highly integrated, multi-channel RF transceiver designed for
low-power wireless applications in the 315/433/868/915MHz ISM bands. The
CC1101 is an upgrade of the CC1100 transceiver with improvements for spurious
response, close-in phase noise, input saturation level, output power ramping and
extended frequency range.
Applications
• Wireless alarm and security systems
• AMR
MSP430
• Industrial monitoring
and control
CPU
• Home and building
automation
26MHz
32kHz
SPI
USART/
USC/
USI
CC1101/
CC2500
I/O
LC
Network
RAM
DMA
Chemical
Sensors
Self-Test
and Bias
Mux
Amp
ADC
LCD
Intl
GDOn
DAC
Example application block diagram – wireless blood gas analyzer.
Sub-1GHz System-on-Chip RF Solution
CC1110/F8/F16/F32
Get samples and datasheets at: www.ti.com/sc/device/CC1110
Key Features
• Low current consumption
• High-performance RF transceiver
core (same as in the CC1100)
• 8- to14-bit ADC with up to eight
inputs
• 21 general I/O pins
• Real-time clock and several timers
• 8/16/32KB in-system programmable
Flash
• 1/2/4KB RAM
• Packaging: 6 x 6mm QLP-36
See also the CC2510 and CC2511—
2.4GHz, System-on-Chip RF solutions.
Need longer RF range? Try the
CC2590/CC2591 2.4GHz RF range
extender for low-power RF ICs.
Visit: www.ti.com/cc2591
The CC1110 is a low-cost System-on-Chip (SoC) IC designed for low-power
and low-voltage wireless communication applications. The CC1110 combines
the excellent perform­ance of the CC1100 RF transceiver with an industry-standard
enhanced MCU, 8/16/32KB of in-system programmable Flash memory, 1/2/4KB of
RAM and many other useful peripherals. Because of several advanced low-power
operating modes, the CC1110 is designed for systems where very low power
consumption is required.
AES 128-Bit
Encryption Engine
Keypad, Analog
Sensor, LCD Display
with SPI or UART
Interface, I2S
Compatible Audio
Codec or Other
Peripherals to
be Controlled
by a MUC
8-14 Bits
8 Channel
ADC +
Temp. Sensor
2x USART
I2S
21 Digital I/O
(Including ADC)
4 Timers: 3x 8-Bit,
1x 16-Bit with ∆Σ Mode
Antenna
8051 Core with
Integrated
Memory
Management
and DMA
1/2/4kb
RAM
RF Front-End
Identical to
C1100
8/16/32kb
FLASH
General-purpose medical device using CC1110. Supports secure
RF link with embedded 128-bit AES hardware encryption.
Diagnostic, Patient Monitoring and Therapy Applications Guide
65
Texas Instruments 2010
Connectivity Solutions for Medical
➔ ZigBee® / Bluetooth® Low Energy
ZigBee® and Bluetooth® Low
Energy Solutions for Medical
Applications
The world is going wireless and medical
applications are no exception. More and
more medical devices, especially patient
monitoring, can benefit from wireless
technology. ZigBee and Bluetooth Low
Energy can be utilized in the consumer
health, wellness, and medical space
across a range of applications.
• Z-Tool (debug tool)
• Development kits: CC2520DK,
CC2530DK and CC2530ZDK
• TIMAC: IEEE 802.15.4 Medium Access
Control (MAC) software stack for TI
IEEE 802.15.4 transceivers and SoCs
TI is part of the Continua Health Alliance
and an active contributor to the evolvement of ZigBee and Bluetooth Low
Energy, the wireless standards for medical applications selected by the alliance.
Applications
• Patient monitoring
• Hospital equipment tracking
TI’s low-power RF portfolio of high-performance RF ICs offers robust and costeffective wireless connectivity solutions
for a variety of medical devices.
With the use of ZigBee wireless sensors,
the patients can move around in the hospital, or even in their homes, and the sensors
will still monitor and send critical health
data to the hospital or doctor. Being independent of a patient’s exact geographical
location has a positive impact on both the
patient and the hospital. The ZigBee standard enables companies to have a simple,
reliable, low-cost and low-power standardbased wireless platform for their application development.
Bluetooth Low-Energy solutions are
designed for low-cost, low-power and
short range connectivity. The technology
enables direct communication to cellular
For more information, visit:
www.ti.com/zigbee
IEEE 802.15.4/ZigBee compliant RF ICs
Bluetooth Low Energy IC
• CC2520: Second-generation 2.4GHz
ZigBee/IEEE 802.15.4 RF transceiver
• CC2530/31: True System-on-Chip
(SoC) with integrated microcontroller
• CC2530ZNP: ZigBee network processor that communicates with any MCU
via an SPI or UART interface
• Reference designs downloadable for
all RF ICs
• CC2540: 2.4 GHz system-on-chip for
Bluetooth low energy applications
• Available in the third quarter of 2010
Bluetooth Low Energy Development Tools
• CC2540DK-MINI
• CC2540DK
ZigBee Software and Development Tools
Applications
• Consumer Health / Medical
• Bluetooth Low Energy Systems
• Wireless Sensor Systems
• Z-Stack™: ZigBee and ZigBee Pro
compliant protocol stack. TI offers this
For more information, visit:
www.ti.com/bluetoothlowenergy
Backlight
Patient Monitoring
and Data Upload
Display
Connectivity
Touch
Screen
Control
LVDS
SerDes
WiFi/Zigbee
PC, Monitor & Keyboard
full ZigBee stack free of charge. Z-Stack
supports over-the air download (OAD) for
firmware upgrades in the field.
phones, laptops and other Bluetooth
enabled devices such as sports and
fitness watches, GPS / handhelds, and
other personal monitoring devices.
Bluetooth
S-Video
TV
Clock
Low Power Wireless
Ethernet
Audio/Video
Codec
Analog Front End
HS USB
Transceiver
(ECG, Pulse Oximetry,
Blood Pressure, Other)
Processor
Integrated ECG
Front End
Keypad
Control
Audio
Feedback
USB
Protection
Keypad
Power
Manager
USB Port
LED
Drivers
Inst AMP
Battery
Charger
Power Source
Buffer AMP
ADC
Human Body
Level
Shifter
Isolation
Product Availability and Design Disclaimer – The system block
diagram depicted above and the devices recommended are
designed in this manner as a reference. Please contact your
local TI sales office or distributor for system design specifics
and product availability.
On/Off
MS/MMC/
SD/SDIO
Card
Core and I/O
Supply
Gas
Gauge
System
Power
AC/DC
Supply
Battery
LEGEND
Plug
Main Power Supply
Processor
Interface
RF/IF
Amplifier
Logic
Power
ADC/DAC
Clocks
Other
Multi-parameter patient monitor
system block diagram.
Diagnostic, Patient Monitoring and Therapy Applications Guide
66
Texas Instruments 2010
Resources
➔ Enhanced Products/Die and Wafer Sales Solutions
Enhanced Products
TI’s Enhanced Product (EP) line offers
design flexibility while still meeting HiRel
and Medical standards for operating
environments where high reliability and
long service life are a requirement. The EP
line offering can benefit avionic, defense,
aerospace, medical, and industrial
designers as well as designers in other
rugged operating environments and
long service life application fields. TI’s
Enhanced Product line is a commercial
of-the-shelf (COTS) solution with the
following key benefits:
• Fabrication/assembly controlled baseline
• Extended product change notification (PCN)
• Extended temperature performance
(typically -55°C to +125°C)
• Standalone data sheet
• Qualification pedigree
• Product traceability
• Long life cycles
TI’s EP products perform to data sheet
specifications in environments that require
extended temperatures (typically -55°C to
+125°C). To ensure that a device exhibits
the highest quality and reliability possible
for targeted applications, TI performs the
TI Die/Wafer Solutions
Texas Instruments offers bare die/wafer
solutions for applications that require
higher levels of integration to reduce
board space. TI provides a wide range
of products in bare die and wafer form.
A variety of testing and qualification
options are available based on product maturity and complexity, as well
as customer requirements. Typical
screening options include DC probe
or AC/DC probe at temperature.
following qualification procedures before
the device is released:
• All EP devices undergo extensive
requalification
• Qualification data is reviewed and
audited for accuracy and compliance
• Reliability and electromigration monitoring is performed at maximum recommended operating conditions in
the targeted package.
• Certified test programs & test hardware
• Electrical characterization is performed
across specified temperature range
• Package performance is confirmed
over extended temperatures (some
mold compounds are not suitable
for extended temperatures).
• Nickel/palladium/gold/lead finish eliminates “tin whisker” reliability issues
• Knowledgeable expertise in medical
related ISO requirements (ISO13485
and ISO14971)
• Certificate of compliance to datasheet
electrical specifications
• Available in military (–55°C/125°C), industrial (–40°C/85°C), commercial (0°C/70°C)
and custom temperature ranges
Enhanced Products
Expected from TI’s EP line:
• Qualification summary report
• Access to leading-edge commercial
technology
• Commitment to the Industrial, Medical,
Avionic and Defense markets
• Customer-driven portfolio
• Enhanced obsolescence management
In addition TI will evaluate the release
of other TI’s catalog devices in an
EP versions based on customer
requirements.
Get more information about TI’s
enhanced products at: www.ti.com/ep
TI offers three categories of die
screening:
Typical processing and capabilities
include:
• Commercial wafers and die
• Mount and bond diagrams
• Probed die – 55°C to +210C°
or special temp
• Shipping: Tape and reel, waffle
packs, custom trays, Gel-Pak®
• Sidewall and visual inspections
• Standard TI wafer fabrication
• Known Good Die (KGD)
• Stand alone datasheet and
warranted over temperature
• Customer defined qualification
• QML Class Q (MIL-STD)
• QML Class V (Space)
• Additional options available
Diagnostic, Patient Monitoring and Therapy Applications Guide
67
For more information regarding
TI’s Die and Wafer offerings, visit
www.ti.com/hirel or email:
[email protected]
Texas Instruments 2010
Resources
➔ TI Design Tools
Below you’ll find a sampling of the design tools TI offers to simplify your design process. To access any of the following application
reports, type the URL www-s.ti.com/sc/techlit/litnumber and replace litnumber with the number in the Lit Number column.
For a complete list of analog application reports, visit: analog.ti.com/appnotes
For a complete list of DSP application reports, visit: www.dspvillage.ti.com/tools
Title
Lit Number
Amplifiers
Single-Supply Operation of Isolation Amplifiers
SBOA004
Very Low Cost Analog Isolation with Power
SBOA013
Boost Instrument Amp CMR with Common-Mode Driven Supplies
SBOA014
DC Motor Speed Controller: Control a DC Motor without Tachometer Feedback
SBOA043
PWM Power Driver Modulation Schemes
SLOA092
Thermo-Electric Cooler Control Using a TMS320F2812 DSP and a DRV592 Power Amplifier
SPRA873
Isolation Amps Hike Accuracy and Reliability
SBOA064
Make a –10V to +10V Adjustable Precision Voltage Source
SBOA052
±200V Difference Amplifier with Common-Mode Voltage Monitor
SBOA005
AC Coupling Instrumentation and Difference Amplifiers
SBOA003
Extending the Common-Mode Range of Difference Amplifiers
SBOA008
Level Shifting Signals with Differential Amplifiers
SBOA038
Photodiode Monitoring with Op Amps
SBOA035
Single-Supply Operation of Isolation Amplifiers
SBOA004
Precision IA Swings Rail-to-Rail on Single 5V Supply
SBOA033
Pressure Transducer to ADC Application
SLOA056
Buffer Op Amp to ADC Circuit Collection
SLOA098
Amplifiers and Bits: An Introduction to Selecting Amplifiers for Data Converters
SLOA035B
Diode-Connected FET Protects Op Amps
SBOA058
Signal Conditioning Piezoelectric Sensors
SLOA033A
Diode-Based Temperature Measurement
SBOA019
Single-Supply, Low-Power Measurements of Bridge Networks
SBOA018
Thermistor Temperature Transducer to ADC Application
SLOA052
Signal Conditioning Wheatstone Resistive Bridge Sensors
SLOA034
Low-Power Signal Conditioning for a Pressure Sensor
SLAA034
Interfacing the MSP430 and TMP100 Temperature Sensor
SLAA151
Data Converters
Configuring I2S to Generate BCLK from Codec Devices & WCLK from McBSP Port
SLAA413
Interfacing the ADS8361 to the TMS320F2812 DSP
SLAA167
Interfacing the TLC2552 and TLV2542 to the MSP430F149
SLAA168
MSC1210 In-Application Flash Programming
SBAA087
Pressure Transducer to ADC Application
SLOA056
Measuring Temperature with the ADS1216, ADS1217, or ADS1218
SBAA073
SPI-Based Data Acquisition/Monitor Using the TLC2551 Serial ADC
SLAA108A
Implementing a Direct Thermocouple Interface with MSP430x4xx and ADS1240
SLAA125A
Using the ADS7846 Touch-Screen Controller with the Intel SA-1110 StrongArm Processor
SBAA070
Complete Temp Data Acquisition System from a Single +5V Supply
SBAA050
Interfacing the ADS1210 with an 8xC51 Microcontroller
SBAA010
Programming Tricks for Higher Conversion Speeds Utilizing Delta Sigma Converters
SBAA005
Retrieving Data from the DDC112
SBAA026
Selecting an ADC
SBAA004
Synchronization of External Analog Multiplexers with the
SBAA013
The DDC112’s Test Mode
SBAA025
Understanding the DDC112’s Continuous and Non-Continuous Modes
SBAA024
Thermistor Temperature Transducer to ADC Application
SLOA052
Diagnostic, Patient Monitoring and Therapy Applications Guide
68
Texas Instruments 2010
Resources
➔ TI Design Tools (Continued)
Title
Lit Number
Low-Power Signal Conditioning for a Pressure Sensor
SLAA034
Data Converters (Continued)
Signal Acquisition and Conditioning with Low Supply Voltages
SLAA018
An Optical Amplifier Pump Laser Reference Design Based on the AMC7820
SBAA072
Processors/Microcontrollers
Programming a Flash-Based MSP430 Using the JTAG Interface
SLAA149
Mixing C and Assembler with the MSP430
SLAA140
Implementing an Ultra-Low-Power Keypad Interface with the MSP430
SLAA139
Heart Rate Monitor and EKG Monitor Using the MSP430FG439
SLAA280
A Single-Chip Pulsoximeter Design Using the MSP430
SLAA274
MSP430 Interface to CC1100/2500 Code Library
SLAS325
Choosing an Ultra-Low-Power MCU
SLAA207
ECG, Pulse Oximeter, Digital Stethoscope Development Kits based on C5505 Processor
SPRT523
MSP430 USB Connectivity Using TUSB3410
SLAA276A
MSP430 Flash Memory Characteristics
SLAA334
Wave Digital Filtering Using the MSP430
SLAA331
Implementing a Real-Time Clock on the MSP430
SLAA076A
Interface
CAN
A System Evaluation of CAN Transceivers
SLLA109
Introduction to the Controller Area Network
SLOA101
Using CAN Arbitration for Electrical Layer Testing
SLLA123
RS-485
Interface Circuits for TIA/EIA-485 (RS-485)
SLLA036B
422 and 485 Standards Overview and System Configurations
SLLA070C
RS-485 for E-Meter Applications
SLLA112
TIA/EIA-485 and M-LVDS, Power and Speed Comparison
SLLA106
USB
VIDs, PIDs and Firmware: Design Decisions When Using TI USB Device Controllers
SLLA154
USB/Serial Applications Using TUSB3410/5052 and the VCP Software
SLLA170
CardBus
PCI1520 Implementation Guide
SCPA033
LVDS
LVDS Design Notes
SLLA014A
Reducing EMI with LVDS
SLLA030C
Performance of LVDS Over Cables
SLLA053B
M-LVDS
Introduction to M-LVDS
SLLA108
M-LVDS Speed Versus Distance
SLLA119
Serdes
Gigabit Transmission Across Cables
SLLA091
Power Controllers
DC Brush Motor Control using the TPIC2101
SLIT110
Power Management
Technical Review of Low Dropout Voltage Regulator Operation and Performance
SLVA072
ESR, Stability, and the LDO Regulator
SLVA115
Extending the Input Voltage Range of an LDO Regulator
SLVA119
High Current LDO Linear Regulators (UCCx81-ADJ, UCCx82-ADJ, UCCx83-ADJ, UCCx85-ADJ)
SLUA256
PowerPAD™ Thermally Enhanced Package
SLMA002
Diagnostic, Patient Monitoring and Therapy Applications Guide
69
Texas Instruments 2010
TI’s Medical guides feature technical and product
information for a variety of medical applications no
matter your need.
• Consumer Medical Applications Guide
• Medical Imaging Applications Guide
• Medical Instruments Applications Guide
To download these product
selection guides, please visit
www.ti.com/medicalguides
TI Worldwide Technical Support
Asia
Internet
TI Semiconductor Product Information Center Home Page
support.ti.com
TI E2ETM Community Home Page
e2e.ti.com
Product Information Centers
Americas
Brazil
Mexico
Phone
Phone
Phone
Fax
Internet/Email
+1(972) 644-5580
0800-891-2616
0800-670-7544
+1(972) 927-6377
support.ti.com/sc/pic/americas.htm
Europe, Middle East, and Africa
Phone
European Free Call
00800-ASK-TEXAS
(00800 275 83927)
International
+49 (0) 8161 80 2121
Russian Support
+7 (4) 95 98 10 701
Note: The European Free Call (Toll Free) number is not active in all c­ ountries.
If you have technical difficulty calling the free call number, please use the
­international number above.
Fax
+(49) (0) 8161 80 2045
Internet
support.ti.com/sc/pic/euro.htm
Japan
Phone
Fax
Internet/Email
Domestic
International
Domestic
International
Domestic
0120-92-3326
+81-3-3344-5317
0120-81-0036
support.ti.com/sc/pic/japan.htm
www.tij.co.jp/pic
Phone
International
+91-80-41381665
Domestic
Toll-Free Number
Australia
1-800-999-084
China
800-820-8682
Hong Kong
800-96-5941
India
1-800-425-7888
Indonesia
001-803-8861-1006
Korea
080-551-2804
Malaysia
1-800-80-3973
New Zealand
0800-446-934
Philippines
1-800-765-7404
Singapore
800-886-1028
Taiwan
0800-006800
Thailand
001-800-886-0010
Fax
+886-2-2378-6808
[email protected]
[email protected]
Internet
support.ti.com/sc/pic/asia.htm
Important Notice: The products and services of Texas Instruments
Incorporated and its subsidiaries described herein are sold subject to TI’s
standard terms and conditions of sale. Customers are advised to obtain
the most current and complete information about TI products and services
before placing orders. TI assumes no liability for applications assistance,
customer’s applications or product designs, software performance, or
infringement of patents. The publication of information regarding any
other company’s products or services does not constitute TI’s approval,
warranty or endorsement thereof.
B121709
The platform bar, E2E Community, C28x, C55x, C674x, C2000, C64x+, DaVinci, Delfino, DLP Discovery,
eXpressDSP, Impedance Track, Microamplifier, MSP430, OMAP, Piccolo, PowerPAD, Sitara, SmartReflex,
Tag-it, TMS320,TMS320C28x, TMS320C5000, TMS320C55x, TMS320C64x+,and Z-Stack are
trademarks of Texas Instruments and Stellaris is a registered trademark of Texas Instruments. The
Bluetooth word mark and logos are owned by Bluetooth SIG, Inc., and any use of such marks by Texas
Instruments is under license. ZigBee is a registered trademark of the ZigBee alliance. All other marks are
the property of their respective owners
© 2010 Texas Instruments Incorporated.
SLYB147A
IMPORTANT NOTICE
Texas Instruments Incorporated and its subsidiaries (TI) reserve the right to make corrections, modifications, enhancements, improvements,
and other changes to its products and services at any time and to discontinue any product or service without notice. Customers should
obtain the latest relevant information before placing orders and should verify that such information is current and complete. All products are
sold subject to TI’s terms and conditions of sale supplied at the time of order acknowledgment.
TI warrants performance of its hardware products to the specifications applicable at the time of sale in accordance with TI’s standard
warranty. Testing and other quality control techniques are used to the extent TI deems necessary to support this warranty. Except where
mandated by government requirements, testing of all parameters of each product is not necessarily performed.
TI assumes no liability for applications assistance or customer product design. Customers are responsible for their products and
applications using TI components. To minimize the risks associated with customer products and applications, customers should provide
adequate design and operating safeguards.
TI does not warrant or represent that any license, either express or implied, is granted under any TI patent right, copyright, mask work right,
or other TI intellectual property right relating to any combination, machine, or process in which TI products or services are used. Information
published by TI regarding third-party products or services does not constitute a license from TI to use such products or services or a
warranty or endorsement thereof. Use of such information may require a license from a third party under the patents or other intellectual
property of the third party, or a license from TI under the patents or other intellectual property of TI.
Reproduction of TI information in TI data books or data sheets is permissible only if reproduction is without alteration and is accompanied
by all associated warranties, conditions, limitations, and notices. Reproduction of this information with alteration is an unfair and deceptive
business practice. TI is not responsible or liable for such altered documentation. Information of third parties may be subject to additional
restrictions.
Resale of TI products or services with statements different from or beyond the parameters stated by TI for that product or service voids all
express and any implied warranties for the associated TI product or service and is an unfair and deceptive business practice. TI is not
responsible or liable for any such statements.
TI products are not authorized for use in safety-critical applications (such as life support) where a failure of the TI product would reasonably
be expected to cause severe personal injury or death, unless officers of the parties have executed an agreement specifically governing
such use. Buyers represent that they have all necessary expertise in the safety and regulatory ramifications of their applications, and
acknowledge and agree that they are solely responsible for all legal, regulatory and safety-related requirements concerning their products
and any use of TI products in such safety-critical applications, notwithstanding any applications-related information or support that may be
provided by TI. Further, Buyers must fully indemnify TI and its representatives against any damages arising out of the use of TI products in
such safety-critical applications.
TI products are neither designed nor intended for use in military/aerospace applications or environments unless the TI products are
specifically designated by TI as military-grade or "enhanced plastic." Only products designated by TI as military-grade meet military
specifications. Buyers acknowledge and agree that any such use of TI products which TI has not designated as military-grade is solely at
the Buyer's risk, and that they are solely responsible for compliance with all legal and regulatory requirements in connection with such use.
TI products are neither designed nor intended for use in automotive applications or environments unless the specific TI products are
designated by TI as compliant with ISO/TS 16949 requirements. Buyers acknowledge and agree that, if they use any non-designated
products in automotive applications, TI will not be responsible for any failure to meet such requirements.
Following are URLs where you can obtain information on other Texas Instruments products and application solutions:
Products
Applications
Amplifiers
amplifier.ti.com
Audio
www.ti.com/audio
Data Converters
dataconverter.ti.com
Automotive
www.ti.com/automotive
DLP® Products
www.dlp.com
Communications and
Telecom
www.ti.com/communications
DSP
dsp.ti.com
Computers and
Peripherals
www.ti.com/computers
Clocks and Timers
www.ti.com/clocks
Consumer Electronics
www.ti.com/consumer-apps
Interface
interface.ti.com
Energy
www.ti.com/energy
Logic
logic.ti.com
Industrial
www.ti.com/industrial
Power Mgmt
power.ti.com
Medical
www.ti.com/medical
Microcontrollers
microcontroller.ti.com
Security
www.ti.com/security
RFID
www.ti-rfid.com
Space, Avionics &
Defense
www.ti.com/space-avionics-defense
RF/IF and ZigBee® Solutions www.ti.com/lprf
Video and Imaging
www.ti.com/video
Wireless
www.ti.com/wireless-apps
Mailing Address: Texas Instruments, Post Office Box 655303, Dallas, Texas 75265
Copyright © 2010, Texas Instruments Incorporated
Was this manual useful for you? yes no
Thank you for your participation!

* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project

Download PDF

advertisement