81-0089RK-01

81-0089RK-01
MATERIAL SAFETY DATA SHEET
Prepared to U.S. OSHA, CMA, ANSI and Canadian WHMIS Standards
1. PRODUCT IDENTIFICATION
CHEMICAL NAME; CLASS: NON-FLAMMABLE GAS MIXTURE
Containing One or More of the Following Components in a Nitrogen Balance Gas:
n-Hexane; 0-0.48%; n-Pentane, 0-0.75%; Carbon Monoxide, 0.0005-1.0%; Propane, 0-1.1%; Oxygen,
0-23.5%
SYNONYMS: Not Applicable
Document Number: 50010
CHEMICAL FAMILY NAME: Not Applicable
FORMULA: Not Applicable
Note: The Material Safety Data Sheet is for this gas mixture supplied in cylinders with 33 cubic feet (935 liters) or less gas capacity (DOT - 39
cylinders). This MSDS has been developed for various gas mixtures with the composition of components within the ranges listed in Section 2
(Composition and Information on Ingredients). Refer to the product label for information on the actual composition of the product.
PRODUCT USE:
U.S. SUPPLIER/MANUFACTURER'S NAME:
ADDRESS:
Calibration of Monitoring and Research Equipment
CALGAZ
821 Chesapeake Drive
Cambridge, MD 21613
1-410-228-6400 (8 a.m. to 5 p.m. U.S. EST)
1-713-868-0440
1-800-231-1366
BUSINESS PHONE:
General MSDS Information:
Fax on Demand:
EMERGENCY PHONE:
Chemtrec: United States/Canada/Puerto Rico:
Chemtrec International:
1-800-424-9300 [24-hours]
1-703-527-3887 [24-hours]
2. COMPOSITION and INFORMATION ON INGREDIENTS
CHEMICAL NAME
n-Hexane
n-Pentane
CAS #
110-54-3
109-66-0
mole %
0-0.48%
0-0.75%
EXPOSURE LIMITS IN AIR
ACGIH-TLV
TWA
STEL
ppm
ppm
50
NE
(skin)
600
NE
OSHA-PEL
PEL
STEL
ppm
ppm
500
NE
50
(Vacated
1989
PEL)
NIOSH
IDLH
ppm
1100
(Based
on 10%
of LEL)
1000
1500
(based
on 10%
of LEL)
600
(Vacated
1989
PEL)
750
(Vacated
1989
PEL)
OTHER
ppm
NIOSH REL:
TWA = 500
DFG MAKs:
TWA = 50 (skin)
PEAK = 8 MAK, 15, min.,
average value
DFG MAK Pregnancy Risk
Classification: C
NIOSH RELs:
TWA = 120
STEL = 610 (ceiling) 15
minutes
DFG MAKs:
TWA = 1000
PEAK = PEAK = 2 MAK 60
min., momentary value
NIOSH RELs:
TWA = 35
STEL = 200 ceiling
DFG MAKs:
TWA = 30
PEAK = 2 MAK, 15 min.,
average value, 1 hr interval
DFG MAK Pregnancy Risk
Classification: B
NIOSH REL: TWA =
1000
DFG MAKs:
TWA = 1000 PEAK =
2 MAK 60 min.,
momentary value
•
•
Carbon Monoxide
630-08-0
0.00051.0%
25
NE
50
35
(Vacated
1989
PEL)
200
(ceiling)
(Vacated
1989
PEL)
1200
•
Propane
74-98-6
Oxygen
7782-44-7
Nitrogen
7727-37-9
0-1.1%
0.001523.5%
Balance
2500
NE
1000
NE
2100
(based
on 10%
of LEL)
•
There are no specific exposure limits for Oxygen. Oxygen levels should be maintained
above 19.5%.
There are no specific exposure limits for Nitrogen. Nitrogen is a simple asphyxiant (SA).
Oxygen levels should be maintained above 19.5%.
NE = Not Established.
See Section 16 for Definitions of Terms Used.
NOTE (1): ALL WHMIS required information is included in appropriate sections based on the ANSI Z400.1-1998 format. This product has been classified in
accordance with the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
3. HAZARD IDENTIFICATION
EMERGENCY OVERVIEW: This product is a colorless gas which is either odorless, or which has a faint, solvent-like odor, if the solvent components (n-Pentane
and n-Hexane) are present. The Carbon Monoxide component of this gas mixture is a chemical asphyxiant and can produce significant, adverse health effects at
relatively low concentrations. Over-exposure to Carbon Monoxide can cause nausea, dizziness, headaches, and collapse. Components of this product (Propane,
n-Pentane, and n-Hexane) can cause anesthetic or peripheral neuropathy effects. Additionally, releases of this product may produce oxygen-deficient atmospheres
(especially in small confined spaces or other poorly-ventilated environments); individuals in such atmospheres may be asphyxiated.
SYMPTOMS OF OVER-EXPOSURE BY ROUTE OF EXPOSURE: The most significant route of over-exposure for this product is by inhalation.
INHALATION: Due to the small size of an individual cylinder of this product, no unusual health effects from over-exposure to the product are
anticipated under routine circumstances of use. Inhalation over-exposures to atmospheres containing more than the Threshold Limit Value of
Carbon Monoxide (25 ppm) can result in serious health consequences. Carbon Monoxide is classified as a chemical asphyxiant, producing a toxic
action by combining with the hemoglobin of the blood and replacing the available oxygen. Through this replacement, the body is deprived of the
required oxygen, and asphyxiation occurs.
NON-FLAMMABLE GAS MIXTURE MSDS - 50010
PAGE 1 OF 6
EFFECTIVE DATE: January 24, 2014
3. HAZARD IDENTIFICATION (continued)
Since the affinity of carbon monoxide for hemoglobin is about 200-300 times that of
HAZARDOUS MATERIAL IDENTIFICATION SYSTEM
oxygen, only a small amount of Carbon Monoxide will cause a toxic reaction to occur.
Carbon Monoxide exposures in excess of 50 ppm will produce symptoms of
poisoning if breathed for a sufficiently long time. INHALATION (continued): If this
HEALTH HAZARD
(BLUE)
product is released in a small, poorly ventilated area (i.e. an enclosed or confined
2
space), symptoms which may develop include the following:
CARBON MONOXIDE
CONCENTRATION OBSERVED EFFECT
All exposure levels:
Over-exposure to Carbon Monoxide can be indicated by the
FLAMMABILITY HAZARD ( RE D) 0
lips and fingernails turning bright red.
200 ppm:
Slight symptoms (i.e. headache) after several hours of
exposure.
400 ppm:
Headache and discomfort experienced within 2-3 hours
0
PHYSICAL HAZARD
(YELLOW)
of exposure.
1,000 -2000 ppm:
Within 30 minutes, slight palpitations of the heart
occurs. Within 1.5 hours, there is a tendency to
stagger.
PROTECTIVE EQUIPMENT
200-2500 ppm:
Within 2 hours, there is mental confusion, headaches,
and nausea. Unconsciousness within 30 minutes.
EYES
RESPIRATORY
HANDS
BODY
> 2500 ppm:
Potential for collapse and death before warning symptoms.
Another hazard associated with this product is the potential for anesthetic and
See Section 8
peripheral neuropathy effects after inhalation over-exposures to the n-Pentane and nHexane components of this product. Specific human over-exposure data are
available for n-Pentane and n-Hexane, as follows:
For Routine Industrial Use and Handling Applications
n-PENTANE
CONCENTRATION OF
OBSERVED EFFECT
Brief (10 minute) up to 5,000 ppm:
No symptoms.
Higher than 5,000 ppm:
Exhilaration, dizziness and headache can occur.
Long term:
Can cause chronic neurological disorder causing damage to the nerves in the hands and feet
(peripheral neuropathy).
n-HEXANE
CONCENTRATION
OBSERVED EFFECT
Brief (10 minute) at 1,500 ppm:
Irritation of the respiratory tract, nausea and headache.
5000 ppm:
Dizziness and drowsiness can occur.
Long term at 500 ppm:
Can affect the nerves in the arms and legs. Effects include numbing or tingling sensations in the
fingers and toes, tiredness, muscle weakness, cramps and spasms in the leg, difficulty in
holding objects or walking, abdominal pains, loss of appetite, weight loss. More serious
exposures can cause damage to the nerves in the hands and feet (peripheral neuropathy).
Eyes and Vision:
Abnormal color perception and pigment changes in the eyes have been reported among
industrial workers exposed to 423-1280 ppm for 5 years or more.
Blood Cells:
Mild forms of anemia have also been associated with exposure to hexane. These are of temporary
nature.
Additionally, if mixtures of this product contain less than 19.5% Oxygen and are released in a small, poorly ventilated area (i.e. an enclosed or
confined space), an oxygen-deficient environment may occur. Individuals breathing such an atmosphere may experience symptoms which include
headaches, ringing in ears, dizziness, drowsiness, unconsciousness, nausea, vomiting, and depression of all the senses. Under some
circumstances of over-exposure, death may occur. The following effects associated with various levels of oxygen are as follows:
OXYGEN
CONCENTRATION
OBSERVED EFFECT
12-16% Oxygen:
Breathing and pulse rate increased, muscular coordination slightly disturbed.
10-14% Oxygen:
Emotional upset, abnormal fatigue, disturbed respiration.
6-10% Oxygen:
Nausea, vomiting, collapse, or loss of consciousness.
Below 6%:
Convulsive movements, possible respiratory collapse, and death.
HEALTH EFFECTS OR RISKS FROM EXPOSURE: An Explanation in Lay Terms. Over-exposure to this gas mixture may cause the following
health effects:
ACUTE: Due to the small size of the individual cylinder of this product, no unusual health effects from exposure to the product are anticipated
under routine circumstances of use. However, Carbon Monoxide (a component of this gas mixture) is toxic to humans. Symptoms of Carbon
Monoxide poisoning can develop gradually, or can arise suddenly, depending on the concentration and duration of exposure. Lips and fingernails
will turn bright red, which is a significant sign of Carbon Monoxide over-exposure. Other symptoms of over-exposure to Carbon Monoxide can
include respiratory difficulty, headaches, shortness of breath, wheezing, headache, blurred vision, memory loss, dizziness, indigestion, nausea,
unconsciousness, and death. Inhalation over-exposures to other components of this gas mixture (Propane, n-Pentane, and n-Hexane) can cause
anesthetic effects and motor neuropathy (i.e. pain and tingling in feet and hands).
Another significant hazard associated with this gas mixture when it contains less than 19.5% oxygen is the potential for exposure to oxygendeficient atmospheres. Symptoms of oxygen deficiency include respiratory difficulty, ringing in ears, headaches, shortness of breath, wheezing,
headache, dizziness, indigestion, nausea, unconsciousness, and death. The skin of a victim of over-exposure may have a blue color.
CHRONIC: Abnormal color perception and pigment changes in the eyes have been reported among persons exposed to 420 -1300 ppm of nHexane for five years. Additionally, long-term exposure to low levels of n-Hexane or n-Pentane can affect the nerves in the arms and legs. Effects
include numbing or tingling sensation, tiredness, cramps, spasms in legs, difficulty holding objects or walking, loss of appetite and weight loss.
Pentane isomers, such as n-Pentane, and Propane can cause sensitization of the heart to epinephrine. Chronic exposure to oxygen-deficient
atmospheres (below 18% oxygen in air) may effect the heart and nervous system. Clinical studies indicate that there is a relationship between
exposure to Carbon Monoxide in specific occupations (i.e. fire-fighters, foundry workers) and an increased incidence of cardiovascular problems.
Carbon Monoxide is a reproductive toxin. Refer to Section 11 (Toxicological Information) of this MSDS for further information.
TARGET ORGANS: ACUTE: Respiratory system, blood system. CHRONIC: Heart, cardiovascular system, central nervous system, reproductive
system.
4. FIRST-AID MEASURES
RESCUERS SHOULD NOT ATTEMPT TO RETRIEVE VICTIMS OF OVER-EXPOSURE TO THIS PRODUCT WITHOUT
ADEQUATE PERSONAL PROTECTIVE EQUIPMENT. At a minimum, Self-Contained Breathing Apparatus and FireRetardant Personal Protective equipment should be worn. Adequate fire protection must be provided during rescue
situations. Victim(s) must be taken for medical attention. Rescuers should be taken for medical attention, if necessary. Take copy of label and
MSDS to physician or other health professional with victim(s).
No unusual health effects are anticipated after exposure to this product, due to the small cylinder size. If any adverse symptom develops after overexposure to this product, remove victim(s) to fresh air, as quickly as possible. Only Trained personnel should administer supplemental oxygen
and/or cardio-pulmonary resuscitation, if necessary. Only trained personnel should administer supplemental oxygen.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: Pre-existing respiratory conditions may be aggravated by over-exposure to this
product. The Carbon Monoxide component of this gas mixture can aggravate some diseases of the cardiovascular system, such as coronary artery
disease and angina pectoris. Because of the presence of n-Hexane or n-Pentane in this product, central nervous system conditions, eye
disorders, or skin problems may be aggravated by over-exposure to this product.
RECOMMENDATIONS TO PHYSICIANS: Treat symptoms and reduce over-exposure. Provide oxygen. Hyperbaric oxygen is the most efficient
antidote to Carbon Monoxide poisoning, the optimum range being 2-2.5 atm. A special mask, or, preferably, a compression chamber to utilize
oxygen at these pressures is required. Avoid administering stimulant drugs.
NON-FLAMMABLE GAS MIXTURE MSDS - 50010
PAGE 2 OF 6
EFFECTIVE DATE: January 24, 2014
5. FIRE-FIGHTING MEASURES
FLASH POINT: Not applicable.
AUTOIGNITION TEMPERATURE: Not applicable.
FLAMMABLE LIMITS (in air by volume, %):
Lower (LEL): Not applicable.
Upper (UEL): Not applicable.
FIRE EXTINGUISHING MATERIALS: Non-flammable gas mixture. Use extinguishing
media appropriate for surrounding fire.
UNUSUAL FIRE AND EXPLOSION HAZARDS: This gas mixture is not flammable;
however, containers, when involved in fire, may rupture or burst in the heat of the fire.
Explosion Sensitivity to Mechanical Impact: Not Sensitive.
Explosion Sensitivity to Static Discharge: Not Sensitive.
NFPA RATING
FLAMMABILITY
0
0
2
HEALTH
SPECIAL FIRE-FIGHTING PROCEDURES: Structural firefighters must wear SelfContained Breathing Apparatus and full protective equipment.
REACTIVITY
OTHER
6. ACCIDENTAL RELEASE MEASURES
LEAK RESPONSE: Due to the small size and content of the cylinder, an accidental release of this product presents significantly less risk of an
oxygen deficient environment and other safety hazards than a similar release from a larger cylinder. However, as with any chemical release,
extreme caution must be used during emergency response procedures. In the event of a release in which the atmosphere is unknown, and in
which other chemicals are potentially involved, evacuate immediate area. Such releases should be responded to by trained personnel using preplanned procedures. Proper protective equipment should be used. In case of a leak, clear the affected area, protect people, and respond with
trained personnel.
For emergency disposal, secure the cylinder and slowly discharge the gas to the atmosphere in a well-ventilated area or outdoors. Allow the gas
mixture to dissipate. If necessary, monitor the surrounding area (and the original area of the release) for Oxygen and Carbon Monoxide. Carbon
Monoxide level must be below exposure level listed in Section 2 (Composition and Information on Ingredients) and Oxygen levels must be above
19.5% before non-emergency personnel are allowed to re-enter area.
If leaking incidentally from the cylinder, contact your supplier.
7. HANDLING and USE
WORK PRACTICES AND HYGIENE PRACTICES: Be aware of any signs of dizziness or fatigue; exposures to fatal concentrations of this product
could occur without any significant warning symptoms, due to oxygen deficiency. Do not attempt to repair, adjust, or in any other way modify
cylinders containing Carbon Monoxide. If there is a malfunction or another type of operational problem, contact nearest distributor immediately.
STORAGE AND HANDLING PRACTICES: Cylinders should be firmly secured to prevent falling or being knocked-over. Cylinders must be
protected from the environment, and preferably kept at room temperature (approximately 21 C, 70 F). Cylinders should be stored in dry, wellventilated areas, away from sources of heat, ignition, and direct sunlight. Protect cylinders against physical damage. Full and empty cylinders
should be segregated. Use a first-in, first-out inventory system to prevent full containers from being stored for long periods of time. These
cylinders are not refillable. WARNING! Do not refill DOT 39 cylinders. To do so may cause personal injury or property damage.
SPECIAL PRECAUTIONS FOR HANDLING GAS CYLINDERS: WARNING! Compressed gases can present significant safety hazards. During
cylinder use, use equipment designed for these specific cylinders. Ensure all lines and equipment are rated for proper service pressure.
PROTECTIVE PRACTICES DURING MAINTENANCE OF CONTAMINATED EQUIPMENT: Follow practices indicated in Section 6 (Accidental
Release Measures). Make certain that application equipment is locked and tagged-out safely. Always use product in areas where adequate
ventilation is provided.
°
°
8. EXPOSURE CONTROLS - PERSONAL PROTECTION
VENTILATION AND ENGINEERING CONTROLS: No special ventilation systems or engineering controls are needed under normal
circumstances of use. As with all chemicals, use this product in well-ventilated areas. If this product is used in a poorly-ventilated area, install
automatic monitoring equipment to detect the levels of components and oxygen.
RESPIRATORY PROTECTION: No special respiratory protection is required under normal circumstances of use. Use supplied air respiratory
protection if Oxygen levels are below 19.5%, or unknown, during emergency response to a release of this product. If respiratory protection is
needed, use only protection authorized in the U.S. Federal OSHA Standard (29 CFR 1910.134), applicable U.S. State regulations, or the Canadian
CSA Standard Z94.4-93 and applicable standards of Canadian Provinces. Oxygen levels below 19.16.33% are considered IDLH by OSHA. In
such atmospheres, use of a full-facepiece pressure/demand SCBA or a full facepiece, supplied air respirator with auxiliary self-contained air
supply is required under OSHA’s Respiratory Protection Standard (1910.134-1998). In the event that exposure limits may be exceeded for
Carbon Monoxide, the following NIOSH respiratory protection equipment guidelines should be consulted.
CARBON MONOXIDE
CONCENTRATION
RESPIRATORY PROTECTION
Up to 350 ppm:
Any Supplied-Air Respirator (SAR).
Up to 875 ppm:
Any SAR operated in a continuous-flow mode.
Up to 1200 ppm:
Any Air-Purifying, Full-Facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister
providing protection against Carbon Monoxide, or any Self-Contained Breathing Apparatus(SCBA) with a full
facepiece, or any SAR with a full facepiece.
Emergency or Planned Entry into Unknown Concentrations or IDLH Conditions: Any SCBA that has a full facepiece and is operated in a
pressure-demand or other positive-pressure mode, or any SAR that has a full facepiece and is operated in a
pressure-demand or other positive-pressure mode in combination with an auxiliary SCBA operated in pressuredemand or other positive-pressure mode.
Escape:
Any Air-Purifying, Full-Facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister
providing protection against Carbon Monoxide, or any appropriate escape-type, SCBA.
EYE PROTECTION: Safety glasses. If necessary, refer to U.S. OSHA 29 CFR 1910.133 or appropriate Canadian Standards.
HAND PROTECTION: No special protection is needed under normal circumstances of use. If necessary, refer to U.S. OSHA 29 CFR
1910.138 or appropriate Standards of Canada.
BODY PROTECTION: No special protection is needed under normal circumstances of use. If a hazard of injury to the feet exists due to falling
objects, rolling objects, where objects may pierce the soles of the feet or where employee’s feet may be exposed to electrical hazards, use foot
protection, as described in U.S. OSHA 29 CFR 1910.136.
9. PHYSICAL and CHEMICAL PROPERTIES
The following physical property values are for the main component, Nitrogen:
GAS DENSITY @ 32°F (0°C) and 1 atm: .072 lbs/ ft3 (1.153 kg/m3)
BOILING POINT: -320.4°F (-195.8°C)
FREEZING/MELTING POINT @ 10 psig -210°C (-345.8°F)
SPECIFIC GRAVITY (air = 1) @ 70°F (21.1°C): 0.906
pH: Not applicable.
SOLUBILITY IN WATER vol/vol @ 32°F (0 C) and 1 atm: 0.023
MOLECULAR WEIGHT: 28.01
EVAPORATION RATE (nBuAc = 1): Not applicable.
EXPANSION RATIO: Not applicable.
ODOR THRESHOLD: Not applicable. Odorless.
SPECIFIC VOLUME (ft3/lb): 13.8
VAPOR PRESSURE @ 70°F (21 .1°C) psig: Not applicable.
COEFFICIENT WATER/OIL DISTRIBUTION: Not applicable.
The following values are for the gas mixture:
APPEARANCE, ODOR AND COLOR: This product is a colorless gas which is either odorless, or which has a faint, solvent-like odor.
HOW TO DETECT THIS SUBSTANCE (warning properties): There are no unusual warning properties associated with a release of this
product. In terms of leak detection, fittings and joints can be painted with a soap solution to detect leaks, which will be indicated by a bubble
formation
°
NON-FLAMMABLE GAS MIXTURE MSDS - 50010
PAGE 3 OF 6
EFFECTIVE DATE: January 24, 2014
10. STABILITY and REACTIVITY
STABILITY: Stable under conditions of normal temperature and pressure.
DECOMPOSITION PRODUCTS: The thermal decomposition products of the Propane, n-Hexane, and n-Pentane components include carbon
oxides. The other components of this gas mixture do not decompose, per se, but can react with other compounds in the heat of a fire.
MATERIALS WITH WHICH SUBSTANCE IS INCOMPATIBLE: Titanium will burn in Nitrogen (the main component of this product). Lithium
reacts slowly with Nitrogen at ambient temperatures. The Propane, n-Pentane, n-Hexane components of this gas mixture are also incompatible
with strong oxidizers (i.e. chlorine, bromine pentafluoride, oxygen, oxygen difluoride, and nitrogen trifluoride). Carbon Monoxide is mildly
corrosive to nickel and iron (especially at high temperatures and pressures).
HAZARDOUS POLYMERIZATION: Will not occur.
CONDITIONS TO AVOID: Contact with incompatible materials. Cylinders exposed to high temperatures or direct flame can rupture or burst.
11. TOXICOLOGICAL INFORMATION
TOXICITY DATA: The following toxicology data are available for the components of this gas mixture that are in 1% or greater concentration:
CARBON MONOXIDE:
nucleated red blood cells, other changes
specified effects, pulse rate increase, without
LC50 (Inhalation-Rat) 1807 ppm/4 hours
LC50 (Inhalation-Mouse) 2444 ppm/4 hours
LC50 (Inhalation-Guinea Pig) 5718 ppm/4 hours
LC50 (Inhalation-wild bird species) 1334 ppm
LCLo (Inhalation-Human) 4 mg/m 3/12 hours:
Behavioral: coma; Vascular: BP lowering not
characterized in autonomic section; Blood:
methemoglobinemia-carboxyhemoglobin
LCLo (Inhalation-Man) 4000 ppm/30 minutes
LCLo (Inhalation-Human) 5000 ppm/5 minutes
LCLo (Inhalation-Dog) 4000 ppm/46 minutes
LCLo (Inhalation-Rabbit) 4000 ppm
LCLo (Inhalation-Mammal-species unspecified)
5000 ppm/5 minutes
TCLo (Inhalation-Human) 600 mg/m 3 /10
minutes: Behavioral: headache
TCLo (Inhalation-Man) 650 ppm/45 minutes:
Blood:
methemoglobinemiacarboxyhemoglobin; Behavioral: changes in
psychophysiological tests
TCLo (Inhalation-Rat) 1800 ppm/1 hour/14
days-intermittent: Cardiac: other changes
TCLo (Inhalation-Rat) 30 mg/m3/8 hours/10
weeks-intermittent: Brain and Coverings: other
degenerative changes; Behavioral :muscle
contraction or spasticity
CARBON MONOXIDE(continued):
TCLo (Inhalation-Rat) 96 ppm/24 hours/90
days-continuous: Blood: pigmented or
TCLo (Inhalation-Rat) 75 ppm/24 hours: female
0-20 day(s) after conception: Reproductive:
Specific
Developmental
Abnormalities:
immune and reticuloendothelial system
TCLo (Inhalation-Mouse) 65 ppm/24 hours:
female
7-18
day(s)
after conception:
Reproductive: Effects on Newborn:
hours: female 6-15 day(s) after conception:
Reproductive: Fertility: post-implantation
mortality (e.g. dead and/or resorbed behavioral
T C L o ( In h al ati o n - Mo u s e) 25 0 ppm /7
implants per total number of implants); Specific
Developmental Abnormalities: musculoskeletal
system
TCLo (Inhalation-Mouse) 125 ppm/24 hours:
female 7-18 day(s) after conception:
Reproductive: Effects on Embryo or Fetus:
fetotoxicity (except death, e.g., stunted fetus)
TCLo (Inhalation-Mouse) 8 pph/1 hour: female 8
day(s) after conception: Reproductive: Fertility: litter
size (e.g. #
fetuses per litter; measured before birth);
Effects on Embryo or Fetus: fetotoxicity (except
death, e.g., stunted fetus), fetal death
TCLo (Inhalation-Mouse) 8 pph/1 hour:
female 8 day(s) after conception:
Reproductive: Specific Developmental
Abnormalities: Central Nervous System
TCLo (Inhalation-Rat) 250 ppm/5 hours/20
days-intermittent: Blood :pigmented or
nucleated red blood cells, changes in other
cell c ount (uns peci fi ed), c hanges in
erythrocyte (RBC) count
TDLo (Subcutaneous-Rat) 5983 mg/kg/18
weeks-intermittent: Blood: changes in serum
composition (e.g. TP, bilirubin, cholesterol)
TCLo (Inhalation-Mouse) 50 ppm/30 daysintermittent: Lungs, Thorax, or Respiration:
structural or functional change in trachea or
bronchi
TCLo (Inhalation-Monkey) 200 ppm/24
hours/90 days-continuous: Blood: pigmented
or nucleated red blood cells, other changes
3
TCLo (Inhalation-Rabbit) 200 mg/m /3 hours/13
weeks-intermittent: Brain and Coverings:
other degenerative changes; Cardiac: other
changes; Blood: hemorrhage
TCLo (Inhalation-Rabbit) 50 ppm/24 hours/8
weeks-continuous: Blood: changes in platelet
count
TCLo (Inhalation-Guinea Pig) 200
3
mg/m /5 hours/4 weeks-intermittent:
Endocrine: hyperglycemia
TCLo (Inhalation-Guinea Pig) 200 mg/m3/5
hours/30
weeks-continuous:
Cardiac:
ar r h yt hm i as (i nc l u di n g c ha n ge s i n
conduction), EKG changes not diagnostic of
TCLo (Inhalation-Rabbit) 180 ppm/24 hours:
female 1-30 day(s) after conception:
Reproductive: Effects on Newborn: stillbirth,
viability index (e.g., # alive at day 4 per # born
alive)
Micronucleus Test (Inhalation-Mouse)1 500
ppm/1 0 minutes
Sister Chromatid Exchange (InhalationMouse) 2500 ppm/1 0 minutes
NITROGEN:There are no specific toxicology
data for Nitrogen. Nitrogen is a simple
asphyxiant, which acts to displace oxygen
in the environment.
OXYGEN:The toxicity data for Oxygen are
related to exposures in a hyperbaric
environment and are not likely to occur in
industrial exposure situations.
PROPANE:
Skin Contact (Rabbit):
Several
formulations containing an isobutanepropane mixture have been tested for skin
irritation effects. All formulations contained
less than 13% propane. All of the
formulations containing propane caused only
mild irritation.
Skin Contact (Rabbit):
Several
formulations containing an isobutane propane mixture have been tested for skin
irritation effects. All formulations contained
fall in BP
TCLo (Inhalation-Guinea Pig) 200 ppm/24
hours/90 days-continuous: Blood: pigmented
or nucleated red blood cells, other changes
TCLo (Inhalation-Rat) 75 ppm/24 hours:
female 0-20 day(s) after conception:
Reproductive: Maternal Effects: other effects;
Effects on Newborn: behavioral
TCLo (Inhalation-Rat) 150 ppm/24 hours:
female 1-22 day(s) after conception:
Reproductive:
Specific
Developmental
Abnormalities: cardiovascular (circulatory)
system
TCLo (Inhalation-Rat) 150 ppm/24 hours:
female 1-22 day(s) after conception:
Reproductive: Effects on Newborn: growth
statistics (e.g.%, reduced weight gain),
behavioral
3
TCLo (Inhalation-Rat) 1 mg/m /24 hours:
female 72 day(s) pre-mating: Reproductive:
Maternal Effects: menstrual cycle changes or
disorders, parturition; Fertility: female fertility
index (e.g. # females pregnant per # sperm
positive females; # females pregnant per #
females mated)
TCLo (Inhalation-Rat) 150 ppm/24 hours:
fem al e 0 -20 day(s ) aft er c onc ept i on:
Reproductive: Effects on Newborn: behavioral
less than 13% propane.
All of the
formulations containing propane caused only
mild irritation.
Effects on Short-Term Inhalation:
Guinea-pigs breathing 5.5% propane by
volume developed tremors after 5 minutes.
Nausea, retching, and stupefaction were
observed when animals were exposed for
30-120 minutes. All the animals survived a
two-hour exposure and had no significant
tissue damage. A gas concentration of 89%
did not cause anesthesia, but depressed the
blood pressure of cats. Inhalation of 10
percent propane by mice and 15% by dogs
c aus ed we ak c ardi ac s ens i t i z at i on,
Presumably, all of these effects are reversible
when exposure ceases. In primates, 10%
propane caused some change in heart
function. At 20% there was aggravation of
these symptoms and respiratory depression.
Effects of Long-Term Inhalation: No
toxicity or abnormalities were observed when
monkeys were exposed to approximately 750
ppm for 90 days. Similar results were obtained
when monkeys were exposed to an aerosol
spray containing 65% propane and isobutane
SUSPECTED CANCER AGENT: The components of this gas mixture are not found on the following lists: FEDERAL OSHA Z LIST, NTP,
CAL/OSHA, and IARC; therefore, they are not considered to be, nor suspected to be, cancer-causing agents by these agencies.
IRRITANCY OF PRODUCT: Contact with rapidly expanding gases can be irritating to exposed skin and eyes.
SENSITIZATION OF PRODUCT: The components of this gas mixture are not known to be skin or respiratory sensitizers. Pentane isomers (i.e. nPentane) and Propane can cause cardiac sensitization to epinephrine.
REPRODUCTIVE TOXICITY INFORMATION: Listed below is information concerning the effects of this gas mixture on the human reproductive
system.
Mutagenicity: The components of this gas mixture are not reported to cause mutagenic effects in humans.
Embryotoxicity: This gas mixture contains components that may cause embryotoxic effects in humans; however, due to the small total amount of
the components, embryotoxic effects are not expected to occur.
Teratogenicity: This gas mixture is not expected to cause teratogenic effects in humans due to the small cylinder size and small total amount
of
all components. The Carbon Monoxide component of this gas mixture which exists up to 1%, can cause teratogenic effects in humans.
Severe exposure to Carbon Monoxide during pregnancy has caused adverse effects and the death of the fetus. In general, maternal
symptoms are an indicator of the potential risk to the fetus since Carbon Monoxide is toxic to the mother before it is toxic to the fetus.
Reproductive Toxicity: The components of this gas mixture are not reported to cause adverse reproductive effects in humans.
A mutagen is a chemical which causes permanent changes to genetic material (DNA) such that the changes will propagate through generation
lines. An embryotoxin is a chemical which causes damage to a developing embryo (i.e. within the first eight weeks of pregnancy in humans), but
the damage does not propagate across generational lines. A teratogen is a chemical which causes damage to a developing fetus, but the damage
does not propagate across generational lines. A reproductive toxin is any substance which interferes in any way with the reproductive process.
BIOLOGICAL EXPOSURE INDICES (BEIs): Biological Exposure Indices (BEIs) have been determined for the Carbon Monoxide and Hexane
components, as follows:
CHEMICAL DETERMINANT
CARBON MONOXIDE
 Carboxyhemoglobin in blood
 Carbon monoxide in end-exhaled air
n-HEXANE
 n-Hexane in end-exhaled air
Notice of Intended Change:
 2,5-Hexanedione in urine
NON-FLAMMABLE GAS MIXTURE MSDS - 50010
SAMPLING TIME
BEI
 End of shift
 End of shift
 3.5% of hemoglobin
 20 ppm
 End of shift
 5 mg/g creatinine
 End of shift at end of workweek
(currently is “Endo of Shift”)
PAGE 4 OF 6
 0.4 mg/L
EFFECTIVE DATE: January 24, 2014
12. ECOLOGICAL INFORMATION
ENVIRONMENTAL STABILITY: The gas will be dissipated rapidly in well-ventilated areas.
EFFECT OF MATERIAL ON PLANTS or ANIMALS: No evidence is currently available on the effects of this gas mixture on plant and animal life.
The Carbon Monoxide component of this gas mixture can be deadly to exposed animal life, producing symptoms similar to those experienced by
humans. Carbon Monoxide may also be harmful to plant life.
EFFECT OF CHEMICAL ON AQUATIC LIFE: No evidence is currently available on this product’s effects on aquatic life. The presence of more
than a trace of the Carbon Monoxide component of this product is a hazard to fish.
13. DISPOSAL CONSIDERATIONS
PREPARING WASTES FOR DISPOSAL PREPARING WASTES FOR DISPOSAL: Waste disposal must be in accordance with appropriate U.S.
Federal, State, and local regulations and those of Canada and its Provinces. Cylinders with undesired residual product may be safely vented
outdoors with the proper regulator. For further information, refer to Section 16 (Other Information).
14.
TRANSPORTATION INFORMATION
THIS GAS MIXTURE IS HAZARDOUS AS DEFINED BY 49 CFR 172.101 BY THE U.S. DEPARTMENT OF TRANSPORTATION.
PROPER SHIPPING NAME:Compressed gases, n.o.s. (*Oxygen, Nitrogen)*or the gas component with the next highest concentration next to
Nitrogen.
HAZARD CLASS NUMBER and DESCRIPTION:
2.2 (Non-Flammable Gas)
UN IDENTIFICATION NUMBER:
UN 1956
PACKING GROUP:
Not applicable.
DOT LABEL(S) REQUIRED:
Class 2.2 (Non-Flammable Gas)
NORTH AMERICAN EMERGENCY RESPONSE GUIDEBOOK NUMBER (2000): 126
MARINE POLLUTANT: The components of this gas mixture are not classified by the DOT as Marine Pollutants (as defined by 49 CFR 172.101,
Appendix B).
SPECIAL SHIPPING INFORMATION: Cylinders should be transported in a secure position, in a well-ventilated vehicle. The transportation of
compressed gas cylinders in automobiles or in closed-body vehicles can present serious safety hazards. If transporting these cylinders in
vehicles, ensure these cylinders are not exposed to extremely high temperatures (as may occur in an enclosed vehicle on a hot day).
Additionally, the vehicle should be well-ventilated during transportation.
Note: DOT 39 Cylinders ship in a strong outer carton (outer package). Pertinent shipping information goes on the outside of the outer package.
DOT 39 Cylinders do not have transportation information on the cylinder itself.
TRANSPORT CANADA TRANSPORTATION OF DANGEROUS GOODS REGULATIONS: This gas mixture is considered as Dangerous Goods,
per regulations of Transport Canada.
PROPER SHIPPING NAME: Compressed gases, n.o.s. (*Oxygen, Nitrogen)*or the gas component with the next highest concentration next to
Nitrogen.
HAZARD CLASS NUMBER and DESCRIPTION:
2.2 (Non-Flammable Gas)
UN IDENTIFICATION NUMBER:
UN 1956
PACKING GROUP:
Not Applicable
HAZARD LABEL:
Class 2.2 (Non-Flammable Gas)
SPECIAL PROVISIONS:
None
EXPLOSIVE LIMIT AND LIMITED QUANTITY INDEX:
0.12
ERAP INDEX:
None
PASSENGER CARRYING SHIP INDEX:
None
PASSENGER CARRYING ROAD VEHICLE OR PASSENGER CARRYING RAILWAY VEHICLE INDEX: 75
NORTH AMERICAN EMERGENCY RESPONSE GUIDEBOOK NUMBER (2000): 126
NOTE: Shipment of compressed gas cylinders via Public Passenger Road Vehicle is a violation of Canadian law (Transport Canada
Transportation of Dangerous Goods Act, 1992)
15. REGULATORY INFORMATION
ADDITIONAL U.S. REGULATIONS:
U.S. SARA REPORTING REQUIREMENTS: The components of this gas mixture are subject to the reporting requirements of Sections 302, 304,
and 313 of Title III of the Superfund Amendments and Reauthorization Act, as follows:
CHEMICAL NAME
SARA 302
SARA 304
SARA 313
(40 CFR 355, Appendix A)
(40 CFR Table 302.4)
(40 CFR 372.65)
n-Hexane
NO
NO
YES
U.S. SARA THRESHOLD PLANNING QUANTITY: There are no specific Threshold Planning Quantities for the components of this gas mixture.
The default Federal MSDS submission and inventory requirement filing threshold of 10,000 lb (4,540 kg) may apply, per 40 CFR 370.20.
U.S. TSCA INVENTORY STATUS: The components of this gas mixture are listed on the TSCA Inventory.
U.S. CERCLA REPORTABLE QUANTITIES (RQ): N-Hexane = 5000 lb (2270 kg)
U.S. STATE REGULATORY INFORMATION: The components of this gas mixture are covered under the following specific State regulations:
Alaska - Designated Toxic and Hazardous
Substances: Carbon Monoxide, Propane, nPentane, n-Hexane.
California - Permissible Exposure Limits for
C h em ic al C o n t am i n a nt s: C a r b o n
Monoxide, Nitrogen, Propane, n-Pentane, nHexane.
Florida - Substance List: Oxygen, Carbon
Monoxide, n-Pentane, n-Hexane.
Illinois - Toxic Substance List: Carbon
Monoxide, Propane, n-Pentane, n-Hexane.
Kansas - Section 302/313 List: No.
Massachusetts - Substance List: Oxygen,
Carbon Monoxide, Propane, n-Pentane, nHexane.
Michigan - Critical Materials Register: No.
Minnesota - List of Hazardous Substances:
Carbon Monoxide, Propane, n-Pentane, nHexane.
Missouri - Employer Information/Toxic
Substance List t: n-Pentane, n-Hexane,
Propane.
New Jersey - Right to Know Hazardous
Substance List: Oxygen, Carbon Monoxide,
Nitrogen, Propane, n-Pentane, n-Hexane
North Dakota - List of Hazardous Chemicals,
Reportable Quantities: No.
Pennsylvania - Hazardous Substance List:
Oxygen, Carbon Monoxide, Nitrogen,
Propane, n-Pentane, n-Hexane.
Rhode Island - Hazardous Substance List:
Oxygen,
Carbon
Monoxide,
Nitrogen,
Propane, n-Pentane, n-Hexane.
Texas - Hazardous Substance List: nPentane, n-Hexane, Propane.
West Virginia - Hazardous Substance List:
n-Pentane, n-Hexane, Propane.
Wisconsin - Toxic and Hazardous
Substances: n-Pentane, n-Hexane, Propane
CALIFORNIA SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT (PROPOSITION 65): Carbon Monoxide is on the California
Proposition 65 lists. WARNING: This gas mixture contains a chemical known to the State of California to cause birth defects or other reproductive
harm.
OTHER U.S. FEDERAL REGULATIONS:
 Carbon Monoxide, Propane, n-Pentane and n-Hexane are subject to the reporting requirements of CFR 29 1910.1000.
 Propane and n-Pentane are subject to the reporting requirements of Section 112(r) of the Clean Air Act. The Threshold Quantity for each of
these gases is 10,000 pounds and so this mixture will not be affected by the regulation.

This gas mixture does not contain any Class I or Class II ozone depleting chemicals (40 CFR part 82).

Nitrogen, Oxygen and n-Hexane are not listed Regulated Substances, per 40 CFR, Part 68, of the Risk Management for Chemical
Releases. Carbon Monoxide, Propane and n-Pentane are listed under this regulation in Table 3, as Regulated Substances
(Flammable), in quantities of 10,000 lbs (4,553 kg) or greater, and so this mixture will not be affected by the regulation
ADDITIONAL CANADIAN REGULATIONS:
CANADIAN DSL/NDSL INVENTORY STATUS: The components of this gas mixture are on the DSL Inventory.
CANADIAN ENVIRONMENTAL PROTECTION ACT (CEPA) PRIORITIES SUBSTANCES LISTS: The components of this gas mixture are not on
the CEPA Priorities Substances Lists.
OTHER CANADIAN REGULATIONS: This gas mixture is categorized as a Controlled Product, Hazard Classes A and D2A, as per the Controlled
Product
NON-FLAMMABLE GAS MIXTURE MSDS - 50010
PAGE 5 OF 6
EFFECTIVE DATE: January 24, 2014
16. OTHER INFORMATION
INFORMATION ABOUT DOT-39 NRC (Non-Refillable Cylinder) PRODUCTS
DOT 39 cylinders ship as hazardous materials when full. Once the cylinders are relieved of pressure (empty) they are not cons idered
hazardous material or waste. Residual gas in this type of cylinder is not an issue because toxic gas mixtures are prohibited. Calibration gas
mixtures typically packaged in these cylinders are Nonflammable n.o.s., UN 1956. A small percentage of calibration ga ses packaged in DOT
39 cylinders are flammable or oxidizing gas mixtures.
For disposal of used DOT-39 cylinders, it is acceptable to place them in a landfill if local laws permit. Their disposal is no different than that
employed with other DOT containers such as spray paint cans, household aerosols, or disposable cylinders of propane (for camping, torch
etc.). When feasible, we recommended recycling for scrap metal content. CALGAZ will do this for any customer that wishes to r eturn
cylinders to us prepaid. All that is required is a phone call to make arrangements so we may anticipate arrival. Scrapping cylinders involves
some preparation before the metal dealer may accept them. We perform this operation as a service to valued customers who want to
participate.
MIXTURES: When two or more gases or liquefied gases are mixed, their hazardous properties may combine to create additional, unexpected
hazards. Obtain and evaluate the safety information for each component before you produce the mixture. Consult an Industrial Hygienist or
other trained person when you make your safety evaluation of the end product. Remember, gases and liquids have propert ies which can
cause serious injury or death.
Further information about the handling of compressed gases can be found in the following pamphlets published by: Compressed G as
Association Inc. (CGA), 1725 Jefferson Davis Highway, Suite 1004, Arlington, VA 22202-4102. Telephone: (703) 412-0900.
P-1
AV-1
“Safe Handling of Compressed Gases in Containers”
“Safe Handling and Storage of Compressed Gases”
“Handbook of Compressed Gases”
This Material Safety Data Sheet is offered pursuant to OSHA’s Hazard Communication Standard, 29 CFR, 1910.1200. Other government regulations must be
reviewed for applicability to this product. To the best of CALGAZ knowledge, the information contained herein is reliable and accurate as of this date; however,
accuracy, suitability or completeness are not guaranteed and no warranties of any type, either express or implied, are provid ed. The information contained
herein relates only to this specific product. If this product is combined with other materials, all component properties must be considered. Data may be changed
from time to time. Be sure to consult the latest edition.
NON-FLAMMABLE GAS MIXTURE MSDS - 50010
PAGE 6 OF 6
EFFECTIVE DATE: January 24, 2014
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