EASY-nLC Series Xcalibur Data System 2.1 or Later User Guide

EASY-nLC Series Xcalibur Data System 2.1 or Later User Guide

1

Installing the EASY-nLC Control Software

This chapter describes how to install the EASY-nLC virtual instrument (VI) control software from the LC Devices DVD. It also describes how to ensure communication between the data system computer and the EASY-nLC instrument.

Contents

Checking the System Prerequisites

Removing a Previous Version of the Instrument Control Software

Installing the Current Version of the Instrument Control Software

Excluding the EASY-nLC from the VirusScan Enterprise

Checking the System Prerequisites

The LC/MS system consists of the EASY-nLC instrument, a Thermo Scientific mass spectrometer, and a data system computer.

Before installing the EASY-nLC VI control software, do the following:

• Install compatible versions of the Thermo Foundation platform and the Xcalibur data system (or equivalent Thermo Scientific data system).

• Ensure that you have administrator rights to install the EASY-nLC VI control software for the Xcalibur application.

• Remove any earlier version of the EASY-nLC VI control software from the data system computer (see

“Removing a Previous Version of the Instrument Control Software” on page 2

).

Thermo Scientific EASY-nLC Series User Guide for the Xcalibur Data System

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Installing the EASY-nLC Control Software

Removing a Previous Version of the Instrument Control Software

Before or after installing the EASY-nLC VI control software, do the following:

• Connect the EASY-nLC instrument to the data system computer through an Ethernet connection (see

“Connecting the EASY-nLC Instrument to the Data System Computer” on page 7

).

• Connect the EASY-nLC instrument to the Thermo Scientific MS detector with a contact closure cable.

The data system synchronizes the run timing between the LC system and the mass spectrometer through the cable. For information about connecting the contact closure cable, refer to the EASY-nLC Series Getting Started Guide.

• Check the laboratory local area network (LAN) port for Internet access to the remote support server. For remote diagnostics, the laboratory must have a LAN port with

Internet access.

The network firewall must allow outgoing Transmission Control Protocol/Internet

Protocol (TCP/IP) traffic from the EASY-nLC instrument to the remote support server at

IP address 195.41.108.93, port 22.

After installing the EASY-nLC VI control software, exclude the software from the virus scanner as described in

“Excluding the EASY-nLC from the VirusScan Enterprise” on page 5

.

Removing a Previous Version of the Instrument Control Software

To remove a previously installed version of the EASY-nLC Xcalibur VI

1. Depending on the Windows operating system, do one of the following:

• For Windows 7, choose Control Panel > Uninstall a Program.

The list of installed programs appears (see

Figure 1

).

• For Windows XP, choose Start > Settings > Control Panel > Add or Remove

Programs.

2

EASY-nLC Series User Guide for the Xcalibur Data System Thermo Scientific

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Installing the EASY-nLC Control Software

Removing a Previous Version of the Instrument Control Software

Figure 1.

Uninstall window for the Windows 7 operating system

Thermo Scientific

2. In the list of installed programs, locate Thermo LC Devices Thermo EASY-nLC

Xcalibur VI.

3. Depending on the operating system, do one of the following:

• For Windows 7, double-click Thermo LC Devices Thermo EASY-nLC Xcalibur VI or click Uninstall. Wait for the program to be removed from the list.

• For Windows XP, click Remove (see Figure 2 ). Wait for the program to be removed

from the list.

Figure 2.

Add or Remove Programs window for the Windows XP operating system

EASY-nLC Series User Guide for the Xcalibur Data System

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1

Installing the EASY-nLC Control Software

Installing the Current Version of the Instrument Control Software

Installing the Current Version of the Instrument Control Software

To install the EASY-nLC Virtual Instrument software

1. Check the installed versions of the Foundation platform and the Xcalibur data system and make sure that these versions are compatible with the LC Devices version that you are

installing (see “System Requirements” on page vii ).

2. Close all running programs before starting the installation.

3. If applicable, remove the previously installed version of the EASY-nLC VI software

(see

“Removing a Previous Version of the Instrument Control Software” on page 2 ).

4. Load the LC Devices DVD into the data system computer, and follow the instructions in the Thermo LC Devices InstallShield Wizard.

5. On the Select Features page of the wizard, select the Thermo check box on the left, and

then select the Thermo EASY-nLC Xcalibur check box on the right (see Figure 3

).

Figure 3.

Select Features page of the Thermo LC Devices InstallShield Wizard

6. When the installation finishes, restart the data system computer.

The installation is complete when you log back in.

4

EASY-nLC Series User Guide for the Xcalibur Data System Thermo Scientific

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Installing the EASY-nLC Control Software

Excluding the EASY-nLC from the VirusScan Enterprise

Excluding the EASY-nLC from the VirusScan Enterprise

The McAfee™ VirusScan™ Enterprise software blocks the Thermo EASY-nLC software when the data system computer uses the Windows 7 operating system.

IMPORTANT For the Windows 7 operating system, you must exclude the EASY-nLC

VI software from the McAfee blocking list. For the Windows XP operating system, exclude the EASY-nLC VI software from the McAfee blocking list only if the EASY-nLC instrument is experiencing communication problems.

To exclude the EASY-nLC software from the VirusScan Enterprise 8.7.0i software

1. Log in to the data system computer as an administrator.

2. Open the McAfee VirusScan Console application as follows: a. Do one of the following:

• On the Windows 7 taskbar, right-click the McAfee icon, , and choose

Manage Features > VirusScan Enterprise.

–or–

• From the Windows 7 desktop, choose Start > All Programs > McAfee >

VirusScan Console.

3. In the Task column, right-click Access Protection and choose Properties from the shortcut menu.

The Access Protection Properties dialog box appears.

4. To open the Rules dialog box, do the following: a. Under Categories, choose Anti-virus Standard Protection.

b. Under Rules, select Prevent IRC Communication.

c.

Click Edit.

The Rules Details dialog box opens.

5. Modify these settings:

• In the Processes to Include box, delete the asterisk.

Note When the Processes to Include box contains only a single asterisk, the virus scanner prevents IRC communication for all processes.

• In the Processes to Exclude box, type Thermo*.

Note When the Processes to Exclude box contains the text Thermo*, the Access

Protection service for Internet Relay Chat (IRC) communication processes ignores processes that begin with Thermo.

Thermo Scientific EASY-nLC Series User Guide for the Xcalibur Data System

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Installing the EASY-nLC Control Software

Excluding the EASY-nLC from the VirusScan Enterprise

6. Click OK to close the Rules Details dialog box.

7. Click OK to close the Access Protection Properties dialog box and accept the new settings.

8. Close the VirusScan Console application.

6

EASY-nLC Series User Guide for the Xcalibur Data System Thermo Scientific

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