Instruction Manual

Read instructions carefully before operating this device.

ΠThis device is not to be used for Human Life Support applications.

• To avoid possible electrical shock, do not operate this device if is wet or has had

liquids spilled onto it.

Ž Service or calibration procedures should only be performed by qualified

personnel familiar with the electrical hazards of line-powered devices.

CWE, Inc.

25 St.Paul’s Road

Ardmore PA 19003 U.S.A.

(610)642-7719 FAX (610)642-1532



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 2

STATEMENT OF WARRANTY

IF THIS INSTRUMENT FAILS WITHIN A PERIOD OF ONE YEAR FROM THE

DATE OF DELIVERY OR INSTALLATION, CWE, INC. WILL, AT ITS OPTION,

REPAIR OR REPLACE IT FREE OF CHARGE. THIS WARRANTY EXCLUDES

DAMAGE INCURRED THROUGH MISUSE OR ACCIDENT. CWE, INC. DOES

NOT ASSUME ANY LIABILITY FOR ANY CONSEQUENTIAL DAMAGES

RESULTING FROM THE USE OF THIS INSTRUMENT.

DEFECTIVE UNITS SHOULD BE RETURNED TO THE FACTORY ALONG

WITH A NOTE DESCRIBING THE NATURE OF THE FAULT. THIS

WARRANTY IS APPLICABLE TO THE ORIGINAL PURCHASER OF THE

INSTRUMENT ONLY, AND IS NOT TRANSFERABLE.

FACTORY SERVICE

Out of warranty or damaged instruments may be returned to the factory freight prepaid for service at prevailing rates. Upon request, a written or verbal quotation for such service will be issued after examination of the unit but prior to commencing repairs or service. Address requests for service or technical information to:

CWE, Incorporated

Technical Support

25 St.Paul's Road

Ardmore, PA 19003 U.S.A.

(610)642-7719

LIFE SUPPORT POLICY

Instruments manufactured by CWE, Incorporated are not authorized for use as critical components in human life support devices or systems. "Life support devices or systems", as used herein, are devices or systems whose failure to perform, whether through misuse, failure, or proper operation, can reasonably be expected to result in significant injury to the operator or subject persons.



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 3

1.0 INTRODUCTION

The SAR-830 series are ventilators for use with small animals up to about 1.5kg in body weight. These ventilators operate using the flow-time principle; a constant airflow is gated into the animal for a set time, thus producing a known tidal volume. This approach permits great flexibility in ventilation, since respiratory rate (RR), inspiratory time (T

I

), and airflow are independently set, and can all be adjusted while the ventilator is running. Model SAR-830/P includes end-inspiratory pressure control, permitting pressure-cycled ventilation in addition to the standard volume-cycled ventilation. Models with an “A” suffix contain a built-in air pump; otherwise a source of compressed air or other gas (3-

20psi) is required for operation. All SAR-830 models are compatible with anesthesia and oxygen. Halothane and Isoflurane



vaporizers are available as an option.

A full set of controls and readouts is provided. Respiratory rate is set and monitored using a digital readout. Inspiratory time and pressure (SAR-830/P models) are set using calibrated 10-turn dials. Inspiratory airflow is set using a front-panel flowmeter/regulator. All models have a built-in digital interface for controlling the ventilator from an external computer.

The SAR-830 can serve as a master controller for ventilating up to four additional animals. This is accomplished using external valve assemblies (CTP-VA series) which plug into a rear-panel expansion connector. Flowmeter manifolds are available for individually adjusting the inspiratory airflow to each animal using a single air source. This feature also permits the SAR-830 to be used with animals up to dog-size by selecting the appropriate external valve assembly.

SAR-830/P Ventilator

Figure 1: Model SAR-830/P Front Panel



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 4

2.0 VENTILATOR CONNECTIONS AND SETUP

Setting up the SAR-830 is straightforward. Of the seven tubing ports on the front panel (see Figure 1), only three are required for basic ventilator operation: the ‘

I

’ and ‘

E

’

CANNULA

ports, and the

FLOW IN

port. The remaining ports have special functions described later.

A suitable source of compressed air or breathing gas is connected to the

FLOW IN

port. If your model has a built-in air pump (‘A’ suffix), connect the

PUMP OUT

port to the

FLOW IN

port with a short length of flexible tubing. In this case, the air pump is drawing room air in through the

PUMP IN

port.

NOTE: If the built-in air pump is being used, do not apply a pressure to the

PUMP IN port. A collapsible bag with a gas

mixture can, however, be connected to this port.

The ‘

I

’ and ‘

E

’

CANNULA

ports are connected to a ‘

Y

’ connector using the supplied tubing. The distal end of this ‘

Y

’ connects directly to the endotracheal tube. Note that the length of this tubing has no effect on ventilatory dead space.

On pressure-cycled models (‘P’ suffix), a tube should connect the distal ‘

Y

’ connector to the

PRESSURE

port on the front panel. This port is used to monitor airway pressure.

Be sure that the

LINE VOLTAGE SELECTOR

switch (rear panel) is set correctly. Plug the line cord into the receptacle on the rear panel, and plug the other end into a grounded power receptacle.

When the

POWER

switch is turned on, the digital rate meter should be lit, indicating that the unit is receiving power.

2.1 SIMPLE SETUP USING PRESSURE MODE (SAR-830/P)

In

PRESSURE

mode, the ventilator will deliver inspiratory flow to the animal until the desired end-inspiratory pressure (as set on the

PRES SET

dial) is reached. When this pressure is reached, inspiratory flow is terminated, and the ventilator begins expiration.

Using this feature, you can quickly set up the ventilator without having to worry about the details of tidal volume setting. The procedure is described below:

1. Set the

RESPIRATORY RATE

to 50-60 (rat) or 90-100 bpm (mouse).

2. Set the

PRES SET

dial to (typically) 12cmH

2

O by dialing in 2.400

(remember that each turn of the 10-turn dial is 5cmH

2

O).

3. Switch the

VOLUME

/

PRES

switch to

PRES

to select pressure mode.

4. Reduce inspiratory flow so the flowmeter shows minimal flow (knob clockwise). Gradually increase flow (knob counterclockwise) until the

INSP

light is on for about ½ of the time (i.e., 50% inspiration).

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2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 5

5. If the

ERR

light blinks, then increase flow, since it is taking too long for inflation to occur with the set respiratory rate.

6. The ventilator will now automatically deliver just enough volume to inflate the lungs to the set pressure on each breath.

2.2 SETTING TIDAL VOLUME (all models)

Two adjustments are required to set any desired tidal volume (VT):

INSPIRATORY FLOW RATE

, and

INSPIRATORY TIME

(T

I

). The Tidal Volume

Tables in the Appendix provide a lookup guide for making these adjustments, or the values can be easily calculated. Some simple considerations will aid in understanding the process. For example, at a respiratory rate of 60 br/min, 1.0 second is available for the entire respiratory cycle. If we choose a 50% inspiratory/expiratory ratio, then 0.5 second is available for inspiration (T

I

). Once T

I

is decided upon, the

INSPIRATORY FLOW

rate is set to deliver the desired volume in the alotted time. The Tidal Volume Tables enable looking up these values, or they can be calculated using simple equations derived as follows:

Basic equations:

VT = Flow X T

I

(volume = flow X time)

T

I

= (1 / RR) / 2 (TI = reciprocal of resp rate, divided by 2)

(assumes 50% inspiration)

Flow = VT / TI (flow = volume divided by time)

Derived equations:

Since T

I

is in seconds, and the flow rate is set in ml/minute, the following will automatically give the flow rate that should be set on the flowmeter:

Flow (ml/min) = (60 X VT) / T

I

If a 50% inspiration/expiration ratio is assumed, determining insp flow further simplifies to the following:

Flow (ml/min) = 2 X VT X RR (2 X tidal volume X resp rate)

Where VT is in ml and RR is in breaths/minute.

This scheme provides extraordinary flexibility over the mechanics and timing of respiration. Once set up for a given VT, it is a simple matter to increase or decrease volume by changing the flow rate, or by increasing or decreasing T

I

. The only constraint is that T

I

not exceed the available time as determined by the

RATE

setting. If T

I

attempts to overlap the next breath, the

ERR

light will blink as a warning that either T

I

or

RESP RATE

should be reduced.



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 6

3.0 OPERATING CONTROLS AND READOUTS

3.1 RATE KNOB AND METER

This knob adjusts the respiratory rate. The actual rate is displayed on the digital rate meter. The range of this control is approximately 5 - 190 breaths/minute. The knob itself is uncalibrated.

3.2 INSPIRATORY TIME (T

I

) KNOB

This ten-turn dial sets the duration of inspiration from zero to five seconds.

Each turn of the dial thus represents ½ second, or 500mS.

NOTE: Faster or slower rates can be achieved using the

DATA

INTERFACE

control inputs.

NOTE: This control takes precedence over the

RATE

setting. Be careful not to set T

I

to a time greater than 1/rate, or the indicated rate will be erroneous. If this condition exists, the

ERROR

light will blink.

3.3 HOLD SWITCH

When switched to

HOLD

, the ventilator is put into a constant expiration mode. To resume normal ventilation, switch to the

NORM

position.

3.4 MANUAL INSPIRATION PUSHBUTTON

Pressing this pushbutton causes inspiration to occur, regardless of the state of the ventilator. Inspiration persists as long as the pushbutton is depressed. This function is useful for generating a sigh, or temporary hyperinflation.

3.5 SYNC OUT JACK (rear panel)

This BNC jack provides a TTL-compatible logic signal corresponding to the current phase of ventilation. Inspiration is logic LOW and expiration is logic HIGH. This signal is also available on pin 20 of the

DATA INTERFACE

(rear panel).

3.6 RATE OUT JACK (rear panel)

This BNC jack provides an analog voltage directly proportional to the respiratory rate. The scale factor is 10mV/breath/minute. This signal is also available on pin 14 of the data interface (rear panel).



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 7

3.7 FLOWMETER

The rotameter-type flowmeter on the front panel is used to set and monitor the

INSPIRATORY FLOW RATE

. Flow is measured from the center of the float ball. The knob at the bottom adjusts the flow. The standard range of 1.0 liter/minute is useful for most rodent-sized animals. Other ranges are available for larger or smaller animals.

3.8 EXTERNAL VALVE JACK (rear panel)

This 4-pin jack is used to connect an

EXTERNAL VALVE ASSEMBLY

to the ventilator for ventilating additional animals. Any of the CTP-VA series valves may be used, enabling the SAR-830 to ventilate multiple animals, or larger animals than can be accommodated using the SAR-830 internal valves. Up to four CTP-VA series assemblies can be connected in parallel for multiple animal ventilation setups.

3.9 VOLUME/PRESSURE SWITCH (SAR-830/P models only)

This switch selects whether the ventilator is operating in

VOLUME

or

PRESSURE

mode. In

VOLUME

mode, the normal tidal volume controls are in effect. In

PRESSURE MODE

, each inspiration will continue until the set endinspiratory pressure has been reached.

3.10 PRESSURE SET DIAL (SAR-830/P models only)

This ten-turn dial sets the end-inspiratory pressure when the ventilator is operated in

PRESSURE

mode. The range of the control is 0 - 50cmH

2

O, or

5cmH

2

O per turn of the dial.

3.11 ANALOG PRESSURE OUT (SAR-830/P models only)

This BNC jack provides an analog voltage corresponding to the airway pressure. The scale factor is 50mV/cmH

2

O. This signal is also available on pin 15 of the

DATA INTERFACE

(rear panel).



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 8

3.12 DATA INTERFACE (rear panel)

This DB-25 connector provides access to a number of monitoring outputs and control inputs. Using these inputs, it is possible to control the ventilator from an external device such as a computer. All the logic inputs are TTL-compatible. The output signals have the same properties as described elsewhere in this manual. The correct mating connector is a

DB-25 male connector.

Standard SAR-830

DATA INTERFACE

connections:

Pin 1 Ground

Pin 14 Analog Rate Output

Pin 15 Analog Pressure Output

Pin 16 Inspiratory Pulse, 100

µ

S pulse at start of inspiration

Pin 17 Expiratory Pulse, 100

µ

S pulse at start of expiration

Pin 18 HOLD Input (NORM=HIGH, HOLD=LOW)

Pin 19 MANUAL Input (NORM=HIGH, MAN INSPIRATION=LOW)

Pin 20 SYNC OUT (EXP=HIGH, INSP=LOW)

SAR-830 DATA PORT

SERIAL PORT

(optional)

GND

RX

TX

GND

1

2

14

15

3

16

4

5

17

18

6

7

19

20

8

9

21

22

10

23

11

12

24

13

25

ANALOG RATE OUT

ANALOG PRESSURE OUT

I PULSE

E PULSE

HOLD

MANUAL

SYNC OUT

EXP INSP

EXTERNAL TRIGGER

(optional)

Required connector is

DB25P male plug



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 9

4.0 PORT CONNECTIONS

4.1 PUMP IN

This is the inlet port for the internal air pump (‘A’ suffix models only).

Normally, room air will be drawn in through this port. Other gasses can be used, but pressure sources should not be directly connected here. If gas mixtures are being used, use a flexible gas collection bag as a collapsible reservoir.

4.2 PUMP OUT

This is the outlet port for the internal air pump (‘A’ suffix models only). To use the internal air pump as the ventilator pressure source, connect this port to the adjacent

FLOW IN

port.

4.3 FLOW IN

This is the main pressure inlet for the ventilator. The compressed air (or other gas) introduced here is the source of inspiratory airflow. This pressure should be within the range 3-20psi. The output of most anesthesia machines can be connected to this port.

4.4 CANNULA ‘I’ AND ‘E’

These ports connect to the animal’s tracheal tube through flexible tubing, and a distal ‘

Y

’ connector. The ‘

I

’ port provides airflow during inspiration.

The

‘

E

’ port accepts passive expiratory airflow during expiration. Since airflow is unidirectional through the tubing connected to these ports, the tubing length does not contribute to dead space. In practice, the tubing lengths should be kept as short as practicable to minimize flow resistance and the compressible volume of the system.

4.5 EXPIRED AIR

This port can be used to collect or analyze expired air. If desired, Positive

End-Expiratory Pressure (PEEP) can be introduced by placing a tube connected to this port under a suitable depth of water.



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 10

4.6 INSPIRATORY VENT

This is where excess inspiratory airflow goes during expiration. During ventilator operation, a constant inspiratory airflow is established. This flow is gated either into the animal through the ‘

I

’ port, or out the

INSP VENT

port. If you are using Halothane or other anesthetic gasses, it may be necessary to collect or scrub the gas coming out this port.

4.7 PRESSURE (SAR-830/P models only)

This female Luer-lok



connection provides the inlet to the internal airway pressure transducer. This should be connected to a tap close to the animal’s tracheal tube. Check this tubing periodically to be sure condensed moisture or other fluids have not entered it. Any blockages will prevent proper operation of pressure-cycled ventilation.

5.0 PRESSURE TRANSDUCER CALIBRATION

The solid-state pressure transducer installed in the SAR-830/P models provides exceptional reliability and stability. To insure correct ventilator operation, the transducer’s calibration should be checked at least every six months.

CAUTION! Do not apply pressures than 10psi to the

PRESSURE

port.

Permanent damage to the transducer will result.

CAUTION! Do not allow water or other fluids to enter the

PRESSURE

port. If condensation is a problem, consider installing a moisture trap in the tubing leading to the transducer. Moisture in the transducer will cause zero offsets to occur, and will affect the accuracy of the transducer.

Calibration is performed as follows. The

TRANSDUCER ZERO

and

SPAN

trimpots are located on the rear panel of the ventilator.

ΠAllow the ventilator to warm up for at least 10 minutes before proceeding.

• Connect a manometer to the

PRESSURE

port. Connect a voltmeter to the

ANALOG

PRESSURE OUT

jack on the rear panel.

Ž With the manometer open to atmosphere (zero pressure), adjust the

TRANSDUCER ZERO

trimpot until the observed reading is 0.000V + .005V.



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 11

• Apply a constant pressure (say 20 cmH

2

O) to the transducer. Adjust the

TRANSDUCER SPAN

trimpot, if necessary, until the meter reading is correct. The scale factor is 50mV/cmH

2

O.

• Repeat steps 3 and 4 above, if necessary, until the readings are correct for both zero and the calibration pressure.

6.0 OPTIONS

Although the four basic configurations of the SAR-830 series meet most small animal ventilation needs, it is possible to customize the ventilator for special purposes. The most common optional configurations are listed below.

6.1 OPTION 041: Mouse-size components

This option provides special miniature internal components, a 100cc/min flowmeter, and a special reduced-volume external tubing set. This has been specially designed and field-tested for ventilating mice, neonatal rats, and other very small animals with tidal volumes in the 0.1cc - 1.0cc range.

6.2 ANESTHESIA SETUPS

CWE, Inc. can provide complete anesthesia setups for small animal use.

A simple system comprises an SAR-830 series ventilator, a Floutec



or

Isotec



vaporizer, and an external flowmeter. The simplest configuration involves connecting the

OUTPUT

of the anesthesia vaporizer to the

FLOW IN

port of the ventilator. For small animals, the SAR-830 internal airpump can be used as the vaporizer pressure source. A preferred method uses a rubber compliance bag (breathing bag) as a reservoir from which the ventilator draws its gas. This places minimal stress on the vaporizer, and allows the ventilator to draw in gas as required. A diagram is included here illustrating the various configurations.



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 12

7.0 EXPANDING THE SAR-830 SYSTEM

One of the most powerful features of the SAR-830 series is its expandability. By simply plugging in an additional valve assembly, an additional animal can be ventilated. Although the SAR-830 is primarily a rodent ventilator, this expansion feature allows much larger animals to be ventilated by adding the appropriate

EXTERNAL VALVE ASSEMBLY

. For each additional animal, you need a valve assembly, a flowmeter/regulator, and an air source. The following table shows which valve assemblies and flowmeters to use for various animals:

Valve Assembly

CTP-VA-1

CTP-VA-1

CTP-VA-3

CTP-VA-4

Flowmeter

EFM-1-100

EFM-1-1

EFM-1-2.5

EFM-1-20

Animal

Mouse

Rat, Guinea pig

Cat, Rabbit

Dog, Goat

SAR-830 VENTILATOR

VALVES

EXTERNAL VALVE ASSEMBLY

I

CANNULA

E FLOW IN

TRACHEAL

TUBE

AIR PUMP

FLOWMETER

Figure 2: Expanding the SAR-830 with an

EXTERNAL VALVE ASSEMBLY

When adding more than one

EXTERNAL VALVE ASSEMBLY

, an electrical cable adapter is required (Part No. MVA-4). This part provides four expansion jacks for adding the valve assemblies. With multiple animal setups, a

FLOWMETER

MANIFOLD

(Part No. EFM-4-x) is useful. With this manifold, one air source can be used for all the animals being ventilated.

Note that each additional valve assembly becomes another ventilator. Any such additional ventilator stations will have identical timing to the host SAR-830, but the tidal volume of each can be set independently by adjusting the individual inspiratory airflows.



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 13

8.0 ORDERING INFORMATION

PART N o

MODEL DESCRIPTION

12-01000 SAR-830 Small Animal Ventilator (without air pump), 115/230V operation

12-01100 SAR-830/A

12-02000 SAR-830/P

12-02100 SAR-830/AP

12-04000 CTP-VA-1

12-05000 CTP-VA-3

12-06000 CTP-VA-4

12-10010 MVA-4

12-10020 EFM-1

12-10021 EFM-4

12-10030 OPTION 020

12-10033 OPTION 024

12-10040 OPTION 031

12-10041 OPTION 032

12-10043 OPTION 0311

12-01020 OPTION 041

Small Animal Ventilator (with internal air pump), 115/230V operation

Small Animal Ventilator, Volume and Pressure cycled (without air pump), 115/230V operation

Small Animal Ventilator, Volume/ Pressure cycled (with internal pump), 115/230V operation

Solenoid Valve Assembly, mouse to Guinea pig size (same as SAR internal)

Solenoid Valve Assembly, cat to small dog size

Solenoid Valve Assembly, dog to goat size

Multi-valve electrical adapter for adding up to 4 external valve assemblies

Flowmeter/regulator with stand, specify range: 100ml, 1, 2.5, 5, 10, or 20 l/min

Flowmeter/regulator manifold w/ 4 flowmeters, with stand, specify range

External Air Pump, 0-1.5l/min range

External Air Pump, 0-25l/min range

Digital Mass Flowmeter, 0-1 l/min

Digital Mass Flowmeter, 0-10 l/min

Flow regulating needle valve for OPTION 03 digital mass flowmeters

SAR-830 special smaller internal valves for body weight 10g-100g

11-10000 CAPSTAR-100 End-tidal CO

2

Analyzer, complete with accessory pack, 115/230V operation

End-tidal CO

2

Analyzer for mice, complete with accessory pack 15-10000 MicroCapstar

13-12000 Halothane Kit Vaporizer, Halothane 0.5 - 5.0% with flowmeter on stand

13-13000 Isoflurane Kit

13-10110 1 liter bag

13-10120 3 liter bag

Vaporizer, Isoflurane 0.5 - 5.0% with flowmeter on stand

Rubber rebreathing bag, 1 liter, with tube fittings

Rubber rebreathing bag, 3 liter, with tube fittings



2005 CWE, Inc. All Rights Reserved

1000

700

500

300

200

100

70

50

30

20

10

7

5

3

2

1

1

10

7

5

4

3

2

SAR-830 series Small Animal Ventilator

Instruction Manual p. 14

APPENDIX 1: TIDAL VOLUME VS. BODY WEIGHT CHARTS

Tidal Volume Chart

Breaths per minute

40

50

60

70

90

100

1

0.7

0.5

0.4

0.3

0.2

0.1

10

40

50

60

70

90

100

20 30 40 50 70

100

Body Weight (g)

200

Tidal Volume Chart

300 400 500 700

1000

2

Breaths per minute

10

15

20

25

30

40

100

3

4

5

6

7 8 9

10

Body Weight (kg)

20



2005 CWE, Inc. All Rights Reserved

30 40 50

SAR-830 series Small Animal Ventilator

Instruction Manual p. 15

APPENDIX 2: TIDAL VOLUME TABLES

Flow Rate (cc/min)

I Time Typ

(sec) Rate 100 200 300 400 500 600 700 800 900 1000

2.4

2.5

2.6

2.7

2.8

2.9

3.0

3.1

1.6

1.7

1.8

1.9

2.0

2.1

2.2

2.3

0.8

0.9

1.0

1.1

1.2

1.3

1.4

1.5

0.1

0.2

0.3

0.4

0.5

0.6

0.7

4.0

4.1

4.2

4.3

4.4

4.5

4.6

4.7

3.2

3.3

3.4

3.5

3.6

3.7

3.8

3.9

4.8

4.9

5.0

7

7

7

6

7

7

7

7

8

8

8

8

9

9

9

9

6

6

6

300

0.2 0.3 0.5 0.7 0.8 1.0 1.2 1.3 1.5 1.7

150

0.3 0.7 1.0 1.3 1.7 2.0 2.3 2.7 3.0 3.3

100

0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0

75

0.7 1.3 2.0 2.7 3.3 4.0 4.7 5.3 6.0 6.7

60

0.8 1.7 2.5 3.3 4.2 5.0 5.8 6.7 7.5 8.3

50

1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0 9.0 10.0

43

1.2 2.3 3.5 4.7 5.8 7.0 8.2 9.3 10.5 11.7

38

1.3 2.7 4.0 5.3 6.7 8.0 9.3 10.7 12.0 13.3

33

1.5 3.0 4.5 6.0 7.5 9.0 10.5 12.0 13.5 15.0

30

1.7 3.3 5.0 6.7 8.3 10.0 11.7 13.3 15.0 16.7

27

1.8 3.7 5.5 7.3 9.2 11.0 12.8 14.7 16.5 18.3

25

2.0 4.0 6.0 8.0 10.0 12.0 14.0 16.0 18.0 20.0

23

2.2 4.3 6.5 8.7 10.8 13.0 15.2 17.3 19.5 21.7

21

2.3 4.7 7.0 9.3 11.7 14.0 16.3 18.7 21.0 23.3

20

2.5 5.0 7.5 10.0 12.5 15.0 17.5 20.0 22.5 25.0

19

2.7 5.3 8.0 10.7 13.3 16.0 18.7 21.3 24.0 26.7

18

2.8 5.7 8.5 11.3 14.2 17.0 19.8 22.7 25.5 28.3

17

3.0 6.0 9.0 12.0 15.0 18.0 21.0 24.0 27.0 30.0

16

3.2 6.3 9.5 12.7 15.8 19.0 22.2 25.3 28.5 31.7

15

3.3 6.7 10.0 13.3 16.7 20.0 23.3 26.7 30.0 33.3

14

3.5 7.0 10.5 14.0 17.5 21.0 24.5 28.0 31.5 35.0

14

3.7 7.3 11.0 14.7 18.3 22.0 25.7 29.3 33.0 36.7

13

3.8 7.7 11.5 15.3 19.2 23.0 26.8 30.7 34.5 38.3

12

4.0 8.0 12.0 16.0 20.0 24.0 28.0 32.0 36.0 40.0

12

4.2 8.3 12.5 16.7 20.8 25.0 29.2 33.3 37.5 41.7

12

4.3 8.7 13.0 17.3 21.7 26.0 30.3 34.7 39.0 43.3

11

4.5 9.0 13.5 18.0 22.5 27.0 31.5 36.0 40.5 45.0

11

4.7 9.3 14.0 18.7 23.3 28.0 32.7 37.3 42.0 46.7

10

4.8 9.7 14.5 19.3 24.2 29.0 33.8 38.7 43.5 48.3

10

5.0 10.0 15.0 20.0 25.0 30.0 35.0 40.0 45.0 50.0

10

5.2 10.3 15.5 20.7 25.8 31.0 36.2 41.3 46.5 51.7

5.3 10.7 16.0 21.3 26.7 32.0 37.3 42.7 48.0 53.3

5.5 11.0 16.5 22.0 27.5 33.0 38.5 44.0 49.5 55.0

5.7 11.3 17.0 22.7 28.3 34.0 39.7 45.3 51.0 56.7

5.8 11.7 17.5 23.3 29.2 35.0 40.8 46.7 52.5 58.3

6.0 12.0 18.0 24.0 30.0 36.0 42.0 48.0 54.0 60.0

6.2 12.3 18.5 24.7 30.8 37.0 43.2 49.3 55.5 61.7

6.3 12.7 19.0 25.3 31.7 38.0 44.3 50.7 57.0 63.3

6.5 13.0 19.5 26.0 32.5 39.0 45.5 52.0 58.5 65.0

6.7 13.3 20.0 26.7 33.3 40.0 46.7 53.3 60.0 66.7

6.8 13.7 20.5 27.3 34.2 41.0 47.8 54.7 61.5 68.3

7.0 14.0 21.0 28.0 35.0 42.0 49.0 56.0 63.0 70.0

7.2 14.3 21.5 28.7 35.8 43.0 50.2 57.3 64.5 71.7

7.3 14.7 22.0 29.3 36.7 44.0 51.3 58.7 66.0 73.3

7.5 15.0 22.5 30.0 37.5 45.0 52.5 60.0 67.5 75.0

7.7 15.3 23.0 30.7 38.3 46.0 53.7 61.3 69.0 76.7

7.8 15.7 23.5 31.3 39.2 47.0 54.8 62.7 70.5 78.3

8.0 16.0 24.0 32.0 40.0 48.0 56.0 64.0 72.0 80.0

8.2 16.3 24.5 32.7 40.8 49.0 57.2 65.3 73.5 81.7

8.3 16.7 25.0 33.3 41.7 50.0 58.3 66.7 75.0 83.3



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 16

APPENDIX 2, cont’d: TIDAL VOLUME TABLES

Flow Rate (cc/min)

Time Typ

(sec) Rate 200 400 600 800 1000 1200 1400 1600 1800 2000

5

5

5

4

4

4

4

4

4

4

4

7

7

7

7

6

6

6

6

5

5

5

4

3

3

3

3

3

3

3

3

17

15

14

13

12

11

10

9

9

8

8

150

75

50

38

30

25

21

19

6.2

6.4

6.6

6.8

7.0

7.2

7.4

7.6

7.8

8.0

8.2

4.0

4.2

4.4

4.6

4.8

5.0

5.2

5.4

5.6

5.8

6.0

8.4

8.6

8.8

9.0

9.2

9.4

9.6

9.8

10.0

1.8

2.0

2.2

2.4

2.6

2.8

3.0

3.2

3.4

3.6

3.8

0.2

0.4

0.6

0.8

1.0

1.2

1.4

1.6

0.7

1.3

2.0

2.7

3.3

4.0

1.3

2.7

4.0

5.3

2.0

4.0

6.0

8.0

2.7

5.3

8.0

10.7

3.3

6.7

10.0

13.3

4.0

8.0

12.0

16.0

4.7

9.3

14.0

18.7

5.3

10.7

16.0

21.3

6.0

12.0

18.0

24.0

6.7

13.3

20.0

26.7

6.7 10.0 13.3 16.7 20.0 23.3 26.7 30.0 33.3

8.0 12.0 16.0 20.0 24.0 28.0 32.0 36.0 40.0

4.7 9.3 14.0 18.7 23.3 28.0 32.7 37.3 42.0 46.7

5.3 10.7 16.0 21.3 26.7 32.0 37.3 42.7 48.0 53.3

6.0 12.0 18.0 24.0 30.0 36.0 42.0 48.0 54.0 60.0

6.7 13.3 20.0 26.7 33.3 40.0 46.7 53.3 60.0 66.7

7.3 14.7 22.0 29.3 36.7 44.0 51.3 58.7 66.0 73.3

8.0 16.0 24.0 32.0 40.0 48.0 56.0 64.0 72.0 80.0

8.7 17.3 26.0 34.7 43.3 52.0 60.7 69.3 78.0 86.7

9.3 18.7 28.0 37.3 46.7 56.0 65.3 74.7 84.0 93.3

10.0 20.0 30.0 40.0 50.0 60.0 70.0 80.0 90.0 100.0

10.7 21.3 32.0 42.7 53.3 64.0 74.7 85.3 96.0 106.7

11.3 22.7 34.0 45.3 56.7 68.0 79.3 90.7 102.0 113.3

12.0 24.0 36.0 48.0 60.0 72.0 84.0 96.0 108.0 120.0

12.7 25.3 38.0 50.7 63.3 76.0 88.7 101.3 114.0 126.7

13.3 26.7 40.0 53.3 66.7 80.0 93.3 106.7 120.0 133.3

14.0 28.0 42.0 56.0 70.0 84.0 98.0 112.0 126.0 140.0

14.7 29.3 44.0 58.7 73.3 88.0 102.7 117.3 132.0 146.7

15.3 30.7 46.0 61.3 76.7 92.0 107.3 122.7 138.0 153.3

16.0 32.0 48.0 64.0 80.0 96.0 112.0 128.0 144.0 160.0

16.7 33.3 50.0 66.7 83.3 100.0 116.7 133.3 150.0 166.7

17.3 34.7 52.0 69.3 86.7 104.0 121.3 138.7 156.0 173.3

18.0 36.0 54.0 72.0 90.0 108.0 126.0 144.0 162.0 180.0

18.7 37.3 56.0 74.7 93.3 112.0 130.7 149.3 168.0 186.7

19.3 38.7 58.0 77.3 96.7 116.0 135.3 154.7 174.0 193.3

20.0 40.0 60.0 80.0 100.0 120.0 140.0 160.0 180.0 200.0

20.7 41.3 62.0 82.7 103.3 124.0 144.7 165.3 186.0 206.7

21.3 42.7 64.0 85.3 106.7 128.0 149.3 170.7 192.0 213.3

22.0 44.0 66.0 88.0 110.0 132.0 154.0 176.0 198.0 220.0

22.7 45.3 68.0 90.7 113.3 136.0 158.7 181.3 204.0 226.7

23.3 46.7 70.0 93.3 116.7 140.0 163.3 186.7 210.0 233.3

24.0 48.0 72.0 96.0 120.0 144.0 168.0 192.0 216.0 240.0

24.7 49.3 74.0 98.7 123.3 148.0 172.7 197.3 222.0 246.7

25.3 50.7 76.0 101.3 126.7 152.0 177.3 202.7 228.0 253.3

26.0 52.0 78.0 104.0 130.0 156.0 182.0 208.0 234.0 260.0

26.7 53.3 80.0 106.7 133.3 160.0 186.7 213.3 240.0 266.7

27.3 54.7 82.0 109.3 136.7 164.0 191.3 218.7 246.0 273.3

28.0 56.0 84.0 112.0 140.0 168.0 196.0 224.0 252.0 280.0

28.7 57.3 86.0 114.7 143.3 172.0 200.7 229.3 258.0 286.7

29.3 58.7 88.0 117.3 146.7 176.0 205.3 234.7 264.0 293.3

30.0 60.0 90.0 120.0 150.0 180.0 210.0 240.0 270.0 300.0

30.7 61.3 92.0 122.7 153.3 184.0 214.7 245.3 276.0 306.7

31.3 62.7 94.0 125.3 156.7 188.0 219.3 250.7 282.0 313.3

32.0 64.0 96.0 128.0 160.0 192.0 224.0 256.0 288.0 320.0

32.7 65.3 98.0 130.7 163.3 196.0 228.7 261.3 294.0 326.7

33.3 66.7 100.0 133.3 166.7 200.0 233.3 266.7 300.0 333.3



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 17

APPENDIX 3: TYPICAL VENTILATOR SETTINGS FOR RODENTS

Body

Weight

(g)

30

Tidal

Volume

(ml)

0.22

Resp

Rate

(br/min)

90

Insp

Flow

(ml/min)

40

Insp

Time

(s)

0.33

Dial

Setting

(turns)

0.67

50

0.40 75 60 0.40 0.80

100

0.90 60 110 0.50 1.00

200

1.70 50 170 0.60 1.20

300

2.30 50 230 0.60 1.20

500

4.00 40 320 0.75 1.50

Note: Settings above are suggested guidelines. You will probably need to adjust the settings for your particular animal, depending on its condition, anesthesia, or other factors.



2005 CWE, Inc. All Rights Reserved

SAR-830 series Small Animal Ventilator

Instruction Manual p. 18

Absorber Cannister

CWE, Inc. 3/30/05

for SAR-830 series ventilators using rubber compliance bag



2005 CWE, Inc. All Rights Reserved

Notes: 1. Adjust flow through vaporizer to keep rubber compliance bag supplied with gas.