User Guide: DuoSpray Ion Source for TripleTOF Systems Operator Guide

Ion Source Maintenance

CAUTION: Potential System Damage: Use only the recommended cleaning method to avoid damaging the equipment.

Required Materials

• 1/4 inch open-ended wrench

• 9/64 inch hex key (L-shaped key supplied)

• 5 mm hex key

• 2.5 mm hex key

• Phillips screwdriver

• Flat-bladed screwdriver

• MS-grade methanol

• HPLC-grade deionized water

• Safety glasses

• Breathing mask and filter

• Powder-free gloves (neoprene is recommended)

• Lab coat

Clean the Probes

WARNING! Hot Surface Hazard: Let the ion source cool for at least 30 minutes before starting any maintenance procedures. Surfaces of the ion source and the vacuum interface components become hot during operation.

Flush the ion source periodically, regardless of the type of compounds sampled. Do this by setting up a method in the software specifically for performing a flushing operation.

1. Switch to a mobile phase that is 1:1 water:acetonitrile or 1:1 water:methanol.

2. Adjust the position of the probes so that they are as far from the orifice as possible.

3. In the software do the following.

a. Set Temperature (TEM) between 500 and 600.

b. Set Ion Source Gas (GS1) and Ion Source Gas 2 (GS2) to at least 40.

c. Set Curtain Gas (CUR) to the highest setting possible without loss of signal.

Operator Guide

RUO-IDV-05-0783-A

DuoSpray ™ Ion Source

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